CN105012708A - Dendrobium candidum Wall.ex Lindl. aerosol - Google Patents
Dendrobium candidum Wall.ex Lindl. aerosol Download PDFInfo
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- CN105012708A CN105012708A CN201510385290.0A CN201510385290A CN105012708A CN 105012708 A CN105012708 A CN 105012708A CN 201510385290 A CN201510385290 A CN 201510385290A CN 105012708 A CN105012708 A CN 105012708A
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- herba dendrobii
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- rhizoma chuanxiong
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Abstract
The present invention relates to the field of medical aerosol for stopping bleeding and relieving pain. A Dendrobium candidum Wall.ex Lindl. aerosol comprises the following raw materials by weight: 70-110 parts of Dendrobium candidum Wall.ex Lindl., 20 to 30 parts of pseudo-ginseng, 15-40 parts of ageratum, 10-30 parts of Ligusticum wallichii, 8-15 parts of propolis, 15-30 parts of glycerol, 7-15 parts of borneol, 2-10 parts of essential oil, 10-15 parts of diethyl phthalate and 120-250 parts of above 90% ethanol. The aerosol has the advantages of portability, rapid onset and definite therapeutic effect and can be used for stopping bleeding, relieving pain and swelling; and the invention also provides a preparation method of the aerosol.
Description
Technical field
The present invention relates to medical hemostatic pain relieving aerosol sectors, the hemostasis and pain-relieving aerosol particularly containing Herba Dendrobii.
Background technology
Aerosol drug can directly arrive site of action or absorption site, there are fairly obvious quick-acting roles and positioning effects, and drug pack is in airtight container, clean and aseptic condition can be kept, decrease the contaminated chance of medicine, and the medicine stopping rear remnants also not easily causes environmental pollution.In addition, because container is opaque, lucifuge, does not directly contact with moisture with the oxygen in air, therefore is conducive to the stability improving medicine.Easy to use, one presses, all-ages, contributes to the medication compliance improving patient, is particularly useful for OTC medicine.Systemic administration can reduce medicine to gastrointestinal zest, and can avoid the first pass effect of liver.Medicinal aerosols etc. are equipped with quantitative valve, therefore dosage is accurate.
Herba Dendrobii (Dendrobium candidum Wall.ex Lindl) is the orchid family Dendrobium Sw, is one of rare Chinese medicine of recording in the Pharmacopoeia of the People's Republic of China, has nourishing YIN and clearing away heat, effect of the stomach reinforcing that promotes the production of body fluid, nourishing the lung to arrest cough.Modern pharmacological research shows that it has and improves immunity of organisms, antitumor and prevent and treat the functions such as cataract.Pharmacology and plant chemical ingredient analysis show that bioactive substance main in Herba Dendrobii is polysaccharide compound, and content is higher.Herba Dendrobii application diversification can be made by Herba Dendrobii being made aerosol, more effectively applying Herba Dendrobii.
Summary of the invention
Goal of the invention of the present invention is: for above-mentioned technical problem, provides a kind of Herba Dendrobii aerosol, specifically provides a kind of Herba Dendrobii aerosol with hemostasis, reducing swelling and alleviating pain.
Technical solution of the present invention is: a kind of Herba Dendrobii aerosol, comprise following parts by weight raw material and method is made, Herba Dendrobii 70-110 part, Radix Notoginseng 20-30 part, Radix agastaches 15-40 part, Rhizoma Chuanxiong 10-30 part, propolis 8-15 part, glycerol 15-30 part, Borneolum Syntheticum 7-15 part, quintessence oil 2-10 part, diethyl phthalate 10-15 part and more than 90% ethanol 120-250 part; And carry out according to following production stage,
Grinding, grinds respectively by Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong, crosses 80-120 mesh sieve;
Extract, tank is put into the Herba Dendrobii after grinding, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong granule, adds more than 90% ethanol 1-10 times liquid, extract 1-4 hour, leave standstill 24 hours, vacuum drawn supernatant;
Configuration, after the extracting solution of Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong and propolis, glycerol, Borneolum Syntheticum, quintessence oil, diethyl phthalate are proportionally configured mix homogeneously, for subsequent use;
Subpackage, be distributed into by the medicinal liquid prepared in clean aluminium pot, sealing, tank freon or butane obtain final products.
Preferably, comprise following parts by weight raw material and method is made, Herba Dendrobii 80-100 part, Radix Notoginseng 25-27 part, Radix agastaches 20-30 part, Rhizoma Chuanxiong 15-25 part, propolis 10-12 part, glycerol 15-20 part, Borneolum Syntheticum 10-12 part, quintessence oil 5-8 part, diethyl phthalate 11-13 part and more than 90% ethanol 150-200 part.
Preferably, comprise following parts by weight raw material and method is made, Herba Dendrobii 100 parts, Radix Notoginseng 25 parts, Radix agastaches 25 parts, Rhizoma Chuanxiong 20 parts, propolis 10 parts, glycerol 20 parts, Borneolum Syntheticum 12 parts, quintessence oil 8 parts, diethyl phthalate 12 parts and more than 90% ethanol 200 parts.
In above-mentioned formula, Herba Dendrobii has enhancing human body immunity power function.Herba Dendrobii can promote the phagocytic function of animal macrophage, and strengthen the activity of the lymphocytic propagation of T and differentiation and NK cell, to specific cellular immunity and humoral immune function, all improve effect.
Radix agastaches has antifungic action, cures mainly dispelling summer-heat from superficies of the body; Removing dampness to restore normal function of the stomach.Catch a cold for the summertime; Cold and heat are had a headache; Breast gastral cavity painful abdominal mass is vexed; Vomiting is had loose bowels; Vomiting during pregnancy; Nasal sinusitis; Hands; Tinea pedis.
Radix Notoginseng has dissipating blood stasis hemostasis, subduing swelling and relieving pain effect; Cure mainly spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Rhizoma Chuanxiong cures mainly activating QI to alleviate the depression, and method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Beneficial effect of the present invention is:
The invention provides a kind of easy to carry, onset rapidly, determined curative effect, for spraying reagent of stopping blooding, ease pain, subsiding a swelling and preparation method thereof.The present invention is evident in efficacy, and at reinforcement blood circulation, blood circulation promoting and blood stasis dispelling, removing toxic substances and promoting subsidence of swelling, removing the necrotic tissue and promoting granulation, skin moistening pain relieving, activate the regeneration capacity of when injected organism tissue.
Detailed description of the invention
The invention discloses a kind of Herba Dendrobii aerosol, comprise following parts by weight raw material to make, Herba Dendrobii 70-110 part, Radix Notoginseng 20-30 part, Radix agastaches 15-40 part, Rhizoma Chuanxiong 10-30 part, propolis 8-15 part, glycerol 15-30 part, Borneolum Syntheticum 7-15 part, quintessence oil 2-10 part, diethyl phthalate 10-15 part and more than 90% ethanol 120-250 part.
Below in conjunction with embodiment, the present invention is described in detail.
Embodiment 1, comprise following parts by weight raw material and method is made, Herba Dendrobii 110 parts, Radix Notoginseng 25 parts, Radix agastaches 20 parts, Rhizoma Chuanxiong 15 parts, propolis 10 parts, glycerol 15 parts, Borneolum Syntheticum 10 parts, quintessence oil 5 parts, diethyl phthalate 11 parts and more than 90% ethanol 250 parts.And carry out according to following production stage,
Grinding, grinds respectively by Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong, crosses 80 mesh sieves;
Extract, tank is put into the Herba Dendrobii after grinding, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong granule, adds more than 90% ethanol, 10 times of liquid, extract 4 hours, leave standstill 24 hours, vacuum drawn supernatant;
Configuration, after the extracting solution of Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong and propolis, glycerol, Borneolum Syntheticum, quintessence oil, diethyl phthalate are proportionally configured mix homogeneously, for subsequent use;
Subpackage, be distributed into by the medicinal liquid prepared in clean aluminium pot, sealing, tank butane obtains final products.
Embodiment 2, comprise following parts by weight raw material and method is made, Herba Dendrobii 100 parts, Radix Notoginseng 25 parts, Radix agastaches 25 parts, Rhizoma Chuanxiong 20 parts, propolis 10 parts, glycerol 20 parts, Borneolum Syntheticum 12 parts, quintessence oil 8 parts, diethyl phthalate 12 parts and more than 90% ethanol 200 parts.And carry out according to following production stage,
Grinding, grinds respectively by Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong, crosses 100 mesh sieves;
Extract, tank is put into the Herba Dendrobii after grinding, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong granule, adds more than 90% ethanol, 8 times of liquid, extract 4 hours, leave standstill 24 hours, vacuum drawn supernatant;
Configuration, after the extracting solution of Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong and propolis, glycerol, Borneolum Syntheticum, quintessence oil, diethyl phthalate are proportionally configured mix homogeneously, for subsequent use;
Subpackage, be distributed into by the medicinal liquid prepared in clean aluminium pot, sealing, tank butane obtains final products.
Embodiment 3, comprise following parts by weight raw material and method is made, Herba Dendrobii 80 parts, Radix Notoginseng 20 parts, Radix agastaches 15 parts, Rhizoma Chuanxiong 10 parts, propolis 8 parts, glycerol 15 parts, Borneolum Syntheticum 7 parts, quintessence oil 5 parts, diethyl phthalate 10 parts and more than 90% ethanol 150 parts.And carry out according to following production stage,
Grinding, grinds respectively by Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong, crosses 80 mesh sieves;
Extract, tank is put into the Herba Dendrobii after grinding, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong granule, adds more than 90% ethanol, 5 times of liquid, extract 3 hours, leave standstill 24 hours, vacuum drawn supernatant;
Configuration, after the extracting solution of Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong and propolis, glycerol, Borneolum Syntheticum, quintessence oil, diethyl phthalate are proportionally configured mix homogeneously, for subsequent use;
Subpackage, be distributed into by the medicinal liquid prepared in clean aluminium pot, sealing, tank freon obtains final products.
For verifying specific implementation effect of the present invention, provide concrete clinical case here, these cases adopt ointment to be make with the formula in embodiment 1.
Certain female, knee traumatic injury, soft tissue swelling, subcutaneous capillary breaks, oozing out, to treatment of wounds of hemorrhage and tissue fluid: after the cleaning of application normal saline, even application medicinal liquid of the present invention, after spraying, wound feels refrigerant, and congestion and swelling pain situation was obviously alleviated in 1-2 days, and redness lightens after 3-4 days.
Certain female, finger weighs wounded, and wound is red and swollen, subcutaneous capillary Rupture haemorrhag, to treatment of wounds: after the cleaning of application normal saline, even application medicinal liquid of the present invention, after spraying, wound feels refrigerant, wound bleeding alleviates disappearance, and within 1 day, the red and swollen situation of wound slows down, and subcutaneous hemorrhage situation disappears.
More than provide detailed description of the invention more of the present invention, it has treatment function and only exemplifies part case and illustrate as effective effect.Can find out that ointment of the present invention can accelerating wound healing process from above-mentioned case, alleviate and avoid bacteriological infection, the pain in agglutination, meet outer damaging the spleen and stomach and requirement is treated to the anti-inflammatory analgetics such as wound, conditioning blood circulation, healing acceleration etc.
Claims (3)
1. a Herba Dendrobii aerosol, it is characterized in that: comprise following parts by weight raw material and method is made, Herba Dendrobii 70-110 part, Radix Notoginseng 20-30 part, Radix agastaches 15-40 part, Rhizoma Chuanxiong 10-30 part, propolis 8-15 part, glycerol 15-30 part, Borneolum Syntheticum 7-15 part, quintessence oil 2-10 part, diethyl phthalate 10-15 part and more than 90% ethanol 120-250 part; And carry out according to following production stage,
Grinding, grinds respectively by Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong, crosses 80-120 mesh sieve;
Extract, tank is put into the Herba Dendrobii after grinding, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong granule, adds more than 90% ethanol 1-10 times liquid, extract 1-4 hour, leave standstill 24 hours, vacuum drawn supernatant;
Configuration, after the extracting solution of Herba Dendrobii, Radix Notoginseng, Radix agastaches and Rhizoma Chuanxiong and propolis, glycerol, Borneolum Syntheticum, quintessence oil, diethyl phthalate are proportionally configured mix homogeneously, for subsequent use;
Subpackage, be distributed into by the medicinal liquid prepared in clean aluminium pot, sealing, tank freon or butane obtain final products.
2. a kind of Herba Dendrobii aerosol according to claim 1, it is characterized in that: comprise following parts by weight raw material and method is made, Herba Dendrobii 80-100 part, Radix Notoginseng 25-27 part, Radix agastaches 20-30 part, Rhizoma Chuanxiong 15-25 part, propolis 10-12 part, glycerol 15-20 part, Borneolum Syntheticum 10-12 part, quintessence oil 5-8 part, diethyl phthalate 11-13 part and more than 90% ethanol 150-200 part.
3. a kind of Herba Dendrobii aerosol according to claim 1, it is characterized in that: comprise following parts by weight raw material and method is made, Herba Dendrobii 100 parts, Radix Notoginseng 25 parts, Radix agastaches 25 parts, Rhizoma Chuanxiong 20 parts, propolis 10 parts, glycerol 20 parts, Borneolum Syntheticum 12 parts, quintessence oil 8 parts, diethyl phthalate 12 parts and more than 90% ethanol 200 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510385290.0A CN105012708A (en) | 2015-06-30 | 2015-06-30 | Dendrobium candidum Wall.ex Lindl. aerosol |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510385290.0A CN105012708A (en) | 2015-06-30 | 2015-06-30 | Dendrobium candidum Wall.ex Lindl. aerosol |
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| CN105012708A true CN105012708A (en) | 2015-11-04 |
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| CN201510385290.0A Pending CN105012708A (en) | 2015-06-30 | 2015-06-30 | Dendrobium candidum Wall.ex Lindl. aerosol |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1153057A (en) * | 1996-05-17 | 1997-07-02 | 云南白药实业股份有限公司 | Yunnan Baiyao aerosol and preparing method thereof |
| CN101264198A (en) * | 2008-04-30 | 2008-09-17 | 通化力神保健品有限公司 | Jinguhuo spraying agent and preparation thereof |
| CN103099967A (en) * | 2013-02-05 | 2013-05-15 | 云南农业大学 | Dendrobe aqueous extract and application thereof |
| CN103961559A (en) * | 2014-04-29 | 2014-08-06 | 广西健宝石斛有限责任公司 | Styptic powder with dendrobium officinale |
| CN103977268A (en) * | 2014-04-28 | 2014-08-13 | 广西健宝石斛有限责任公司 | External injury-healing ointment |
-
2015
- 2015-06-30 CN CN201510385290.0A patent/CN105012708A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1153057A (en) * | 1996-05-17 | 1997-07-02 | 云南白药实业股份有限公司 | Yunnan Baiyao aerosol and preparing method thereof |
| CN101264198A (en) * | 2008-04-30 | 2008-09-17 | 通化力神保健品有限公司 | Jinguhuo spraying agent and preparation thereof |
| CN103099967A (en) * | 2013-02-05 | 2013-05-15 | 云南农业大学 | Dendrobe aqueous extract and application thereof |
| CN103977268A (en) * | 2014-04-28 | 2014-08-13 | 广西健宝石斛有限责任公司 | External injury-healing ointment |
| CN103961559A (en) * | 2014-04-29 | 2014-08-06 | 广西健宝石斛有限责任公司 | Styptic powder with dendrobium officinale |
Non-Patent Citations (1)
| Title |
|---|
| 王春兰等: "石斛小菇的药理活性研究", 《微生物学通报》 * |
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Application publication date: 20151104 |