CN105012360A - Throat-clearing-and-nourishing lozenge - Google Patents
Throat-clearing-and-nourishing lozenge Download PDFInfo
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- CN105012360A CN105012360A CN201510410638.7A CN201510410638A CN105012360A CN 105012360 A CN105012360 A CN 105012360A CN 201510410638 A CN201510410638 A CN 201510410638A CN 105012360 A CN105012360 A CN 105012360A
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- kernel
- semen capparis
- clearing
- capparis
- semen
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- Medicinal Preparation (AREA)
Abstract
The invention discloses a throat-clearing-and-nourishing lozenge. The lozenge is composed of, by mass, 10-15% of Carpparis masaikai kernel extract, 5-15% of food adhesive, 57-77% of filler, 3-5% of menthol, 3-5% of borneol and 2-3% of distilled water. The throat-clearing-and-nourishing lozenge has effects of refreshing, preventing inflammation, nourishing liver, suppressing cough and improving oral humidity and can effectively relieve mouth parching and tongue scorching caused by smoking so as to achieve the objective of throat clearing and nourishing.
Description
Technical field
The present invention relates to a kind of buccal tablet for clearing and moistening throat, be specifically related to a kind of buccal tablet for clearing and moistening throat containing Semen Capparis kernel extract.
Background technology
Along with the raising of people's living standard and the development of global Tobacco Control campaign, cigarette consumption person more and more pays close attention to smoking and healthy problem.It is reported, smoking can cause death, and containing more than 7000 multiple compounds in tobacco smoke, wherein 69 kinds is known carcinogen.From different angles, thousands of scientific evidence confirms that smoking and second hand smoking are the important risk factor of the various diseases morbidities such as pulmonary carcinoma, chronic respiratory system diseases, coronary heart disease, apoplexy and death respectively.In addition, smoking can also cause xerostomia, dryness of the tongue and throat dry and astringent, and then may dental caries be caused, periodontal, fungal infection, the appearance of a series of diseases such as masticatory function obstacle.
Semen Capparis is used as medicine to remove the peel kernel, is heat-clearing and toxic substances removing, the common medicine of promoting the production of body fluid for nourishing the lung and clear larynx fire.That there is resolving heat and reducing pathogenic fire, promoting the production of body fluid to quench thirst and treatment laryngopharynx swelling and pain, ulcerative gingivitis aphtha, deficiency of body fluid, the important medicine source of dry mouth and tougue drugs with function " Ruan Shi shangqing pill ".Semen Capparis kernel is aid digestion in addition, the effects such as relieving alcoholic intoxication.In Yunnan Province, just there is the custom of chewing Semen Capparis kernel treatment oral inflammation from ancient times.Show according to correlational study, Semen Capparis kernel extracting solution can improve saliva of buccal cavity secretion significantly, improves oral cavity humidity, thus effectively reduces dental caries, periodontal, fungal infection, the generation of the diseases such as masticatory function obstacle.
Microwave radiation enzyme denaturing technology adopts ultra high frequency electrical field to carry out heat treated to material, and firing rate is fast, and material inner and outer temperatures gradient negative effect is little, and material surface and inside are heated simultaneously, thus the enzyme molecule making material surperficial and inner inactivation simultaneously; In addition, the Electromagnetic Environmental Effect of microwave radiation can also impel the passivation of enzyme molecular activity, has unique biological effect, thus improves local flavor and the quality of product.Compared to boiling water heating enzyme denaturing, supertension enzyme denaturing, the synchronous enzyme denaturing of Infrared Heating, the steam enzyme denaturing etc. of routine, microwave radiation enzyme denaturing can solve being difficult to existing for above-mentioned conventional enzyme inactivating method effectively makes the thorough passivation of enzyme, the heat time heating time long and internal batch enzyme denaturing shortcoming such as not thorough.
Atomizing freeze drying, as a kind of dry technology of novelty, has obvious advantage compared to traditional spraying dry and Freeze Drying Technique.Atomizing freeze drying by high pressure, solution is become very little drop through nozzle ejection, atomization and enters rapidly in the spray tank that cryogen (liquid nitrogen, liquid carbon dioxide) is housed.Due to the existence of cryogen in spray tank, a low temperature environment will be defined in spray tank, because the rate of heat transfer in this low temperature environment is very high, droplet be solidified instantaneously, form the powder freezed.Finally by sublimation principle, vacuum lyophilization is carried out to the above-mentioned powder freezed and namely obtains end product.
Summary of the invention
The object of the present invention is to provide a kind of buccal tablet for clearing and moistening throat, this buccal tablet effectively can alleviate the dry mouth and tougue and laryngopharynx swelling and pain symptom that smoking causes, thus is conducive to improving oral health.Buccal tablet of the present invention comprises Semen Capparis kernel extract, food adhesive, filler, Mentholum and Borneolum Syntheticum; The content of described Semen Capparis kernel extract account for buccal tablet gross mass 10% ~ 15%, food adhesive account for buccal tablet gross mass 5% ~ 15%, filler account for buccal tablet gross mass 57% ~ 77%, Mentholum account for buccal tablet gross mass 3% ~ 5%, Borneolum Syntheticum account for buccal tablet gross mass 3% ~ 5%, distilled water 2% ~ 3%.
Described food adhesive is microcrystalline Cellulose.
Described filler is maltodextrin.
The preparation method of described Semen Capparis kernel extract is as follows:
(1) get fresh mature Semen Capparis fruit, obtain Semen Capparis kernel after peelling off shell and mesochite, Semen Capparis kernel is placed in refrigerator, regulate temperature to be 4 DEG C of preservations, for subsequent use; Take out Semen Capparis kernel to pulverize, obtaining fineness after sieving is 80 ~ 120 object Semen Capparis kernel powder;
(2) step (1) Semen Capparis kernel powder is laid on bottom microwave oven special box, makes Semen Capparis kernel powder thickness be 4-6mm, the sealing of microwave oven special box is placed in Microwave Extraction Apparatus and carries out microwave radiation processing; Wherein, the microwave radiation processing time is 60 ~ 70 seconds, and microwave irradiation power is 10 ~ 15 watts/gram;
(3) the Semen Capparis kernel powder after step (2) microwave radiation enzyme denaturing is taken out, be placed in ice-water bath and be cooled to room temperature, namely obtain the Semen Capparis kernel powder after microwave radiation enzyme denaturing;
(4) 60 DEG C ~ 70 DEG C hot water constant temperatures of its quality 3 ~ 4 times of the Semen Capparis kernel powder after step (3) microwave radiation enzyme denaturing are soaked 3 ~ 4h, extracting solution 120 object screen filtrations, collect filtrate, filtering residue squeezer squeezes, squeeze the juice and to merge with filtrate, then use filter press or rotary drum filter to carry out fine straining, obtain fine straining liquid;
(5) fine straining liquid is carried out vacuum concentration, make concentrated after volume be condensate precursor long-pending 1/3 ~ 1/2, vacuum is 0.01 ~ 0.03MPa, and temperature is 60 ~ 70 DEG C;
(6) by the method for pressure atomization step (5) concentrated solution directly sprayed into and be equipped with in the spray tank of cryogen; Wherein, the atomizing pressure of pressure atomization is 6 MPa, and the concentrated solution containing Semen Capparis kernel extract is directly frozen into small solid particles in spray tank;
(7) small solid particles of gained of step (6) being sprayed, freezed carries out vacuum lyophilization, vacuum drying vacuum 10 Pa, first
-40 DEG C of dryings 4 hours, then in 12 hours temperature from
-40 DEG C rise to 25 DEG C, and namely last 25 DEG C of dryings obtain Semen Capparis kernel extract for 4 hours.
Compared with prior art, major advantage is as follows in the present invention:
1, contain Semen Capparis kernel extract in buccal tablet of the present invention, can effectively improve salivation amount, improve oral cavity humidity, refrigerant sense can be brought again, improve oral health.Meanwhile, in Semen Capparis kernel extract powder, be also rich in sweet protein, be mainly used as the food additive such as food processing, beverage, chewing gum, confection, milk product, health product.The feature of sweet protein is that sugariness is high, and heat is minimum, pure taste, safety non-toxic, non-carcinogenesis, the aminoacid containing needed by human, and edible more also can not causing urinates the disease such as disease, obesity, hypertension, coronary heart disease, is desirable sweeting agent.Semen Capparis kernel is used for chewing food in addition, then drinks cold water or warm water, namely produces giving off a strong fragrance taste, makes eater joyful, for up to half an hour.
2, contain microcrystalline Cellulose in buccal tablet of the present invention, microcrystalline Cellulose is a kind of important dietary cellulose and desirable food supplement, mainly makes diluent and binding agent herein, also has certain lubrication and disintegration.
3, maltodextrin is contained in buccal tablet of the present invention, maltodextrin is as main filler, and meanwhile, maltodextrin contains a large amount of polysaccharides, in addition also containing calcium, ferrum etc. to the useful trace element of human body and mineral, and the substance metabolism of human normal can be promoted.
4, buccal tablet of the present invention is also containing a small amount of Mentholum and Borneolum Syntheticum, and Mentholum can be used as aromatic and flavoring agent, can produce refrigerant sense to alleviate discomfort and pain for mucosa; Borneolum Syntheticum has effect that is antibacterial, antiinflammatory, swells and ache for sore throat aphtha, skin infection, and not holding back etc. after bursting has certain drug effect.
5, contain Semen Capparis kernel extract in buccal tablet of the present invention, described Semen Capparis kernel extract adopts novel preparation technology to obtain, and the novel preparation technology of described Semen Capparis kernel extract relates to microwave radiation enzyme denaturing, atomizing freeze drying.
6, microwave radiation enzyme denaturing efficiency of the present invention is high, can extend the Semen Capparis kernel storage life.In addition, microwave radiation enzyme denaturing can also keep the biological activity of Semen Capparis kernel, nutritional labeling and exterior quality better.
7, atomizing freeze drying of the present invention carries out under low temperature, oxygen free condition, farthest can reduce the destruction of biological activity and nutritional labeling in Semen Capparis kernel, can obtain the Semen Capparis kernel extract powder of stay in grade.
Detailed description of the invention
Below by embodiment, the present invention is described in further detail, but scope is not limited to described content.
Embodiment 1: this buccal tablet for clearing and moistening throat constituent and mass percent are: Semen Capparis kernel extract 10%, microcrystalline Cellulose 15%, maltodextrin 67%, Mentholum 3%, Borneolum Syntheticum 3%, distilled water 2%.
The manufacture method of described Semen Capparis kernel extract is as follows:
1, get fresh mature Semen Capparis fruit, obtain Semen Capparis kernel after peelling off shell and mesochite, Semen Capparis kernel is placed in refrigerator, regulate temperature to be 4 DEG C of preservations, for subsequent use;
2, take out Semen Capparis kernel, by pulverizing, obtaining fineness after sieving is 80 object Semen Capparis kernel powder;
3, step 2 gained Semen Capparis kernel fine powder is layered on bottom microwave oven special box, makes Semen Capparis kernel powder thickness remain on 5 millimeter, the sealing of microwave oven special box is placed in Microwave Extraction Apparatus and carries out microwave radiation processing; Wherein, the microwave radiation processing time is set as 70 seconds, and microwave irradiation power is set as 10 watts/gram;
4, the Semen Capparis kernel powder after step 3 microwave radiation enzyme denaturing is taken out, be placed in ice-water bath and be cooled to room temperature, namely obtain the Semen Capparis kernel powder after microwave radiation enzyme denaturing;
5, by gained Semen Capparis kernel powder after step 4 microwave radiation enzyme denaturing with 70 DEG C of hot water of its quality 4 times and keep water temperature soak 4h, extracting solution 120 object screen filtrations, collect filtrate, filtering residue squeezer squeezes, squeeze the juice and to mix with filtrate, then use filter press or rotary drum filter to carry out fine straining, obtain fine straining liquid;
6, step 5 fine straining liquid is carried out vacuum concentration, make concentrated after volume be about condensate precursor long-pending 1/3 ~ 1/2, vacuum is 0.01 ~ 0.03MPa, and temperature is 60 ~ 70 DEG C;
7, directly spray in the spray tank that cryogen (liquid nitrogen) is housed with the concentrated solution that step 6 to be concentrated gained by the method for pressure atomization, wherein, the atomizing pressure of pressure atomization is 6 MPa.Concentrated solution containing Semen Capparis extract is directly frozen into small solid particles in spray tank;
8, the small solid particles of gained of step 7 being sprayed, freeze all is transferred in vacuum freeze drier and is carried out vacuum lyophilization, vacuum drying vacuum 10 Pa, first
-40 DEG C of dryings 4 hours, then in 12 hours temperature from
-40 DEG C rise to 25 DEG C, and namely last 25 DEG C of dryings obtain Semen Capparis kernel extract for 4 hours;
the manufacture method of described buccal tablet for clearing and moistening throat:
1, get described Mentholum, Borneolum Syntheticum by pulverizing, obtaining fineness after sieving is 80 object Mentholums, borneol powder;
2, described Semen Capparis kernel extract, microcrystalline Cellulose, maltodextrin, Mentholum, Borneolum Syntheticum, distilled water are poured in mixer, abundant mix homogeneously;
3, the material tablet machine mixed is carried out tabletting by 1g/ sheet, obtain buccal tablet for clearing and moistening throat of the present invention.
Embodiment 2: this buccal tablet for clearing and moistening throat constituent and mass percent are: Semen Arecae kernel extract 12%, microcrystalline Cellulose 10%, maltodextrin 68%, horsemint brain 4%, Borneolum Syntheticum 4%, distilled water 2%.
The manufacture method of Semen Capparis kernel extract powder in described buccal tablet for clearing and moistening throat:
1, get fresh mature Semen Capparis fruit, obtain Semen Capparis kernel after peelling off shell and mesochite, Semen Capparis kernel is placed in refrigerator, regulate temperature to be 4 DEG C of preservations, for subsequent use;
2, take out Semen Capparis kernel, by pulverizing, obtaining fineness after sieving is 100 object Semen Capparis kernel powder;
3, step 2 gained Semen Capparis kernel fine powder is layered on bottom microwave oven special box, Semen Capparis kernel powder thickness is made to remain on 5 millimeter, the sealing of microwave oven special box is placed in Microwave Extraction Apparatus and carries out microwave radiation processing, wherein, the microwave radiation processing time is set as 65 seconds, and microwave irradiation power is set as 12 watts/gram;
4, the Semen Capparis kernel powder after step 3 microwave radiation enzyme denaturing is taken out, be placed in ice-water bath and be cooled to room temperature, namely obtain the Semen Capparis kernel powder after microwave radiation enzyme denaturing;
5, by gained Semen Capparis kernel powder after step 4 microwave radiation enzyme denaturing with 65 DEG C of hot water of its quality 3.5 times and keep water temperature soak 3.5h, extracting solution 120 object screen filtrations, collect filtrate, filtering residue squeezer squeezes, squeeze the juice and to mix with filtrate, then use filter press or rotary drum filter to carry out fine straining, obtain filtrate.
6, step 5 fine straining gained filtrate is carried out vacuum concentration, make the volume after concentrating be about before concentrating 1/3 ~ 1/2, vacuum is 0.01 ~ 0.03MPa, and temperature is 60 ~ 70 DEG C;
7, directly spray in the spray tank that cryogen (liquid carbon dioxide) is housed with the concentrated solution that step 6 to be concentrated gained by the method for pressure atomization, wherein, the atomizing pressure of pressure atomization is 6 MPa, and the concentrated solution containing Semen Capparis extract is directly frozen into small solid particles in spray tank;
8, the small solid particles of gained of step 7 being sprayed, freeze all is transferred in vacuum freeze drier and is carried out vacuum lyophilization, vacuum drying vacuum 10 Pa, first
-40 DEG C of dryings 4 hours, then in 12 hours temperature from
-40 DEG C rise to 25 DEG C, and namely last 25 DEG C of dryings obtain Semen Capparis kernel extract for 4 hours;
the manufacture method of described buccal tablet for clearing and moistening throat:
1, get described Mentholum, Borneolum Syntheticum by pulverizing, obtaining fineness after sieving is 100 object Mentholums, borneol powder.
2, described Semen Capparis kernel extract, microcrystalline Cellulose, maltodextrin, Mentholum, Borneolum Syntheticum, distilled water are poured in mixer, abundant mix homogeneously;
3, the material tablet machine mixed is carried out tabletting by 1g/ sheet, obtain buccal tablet for clearing and moistening throat of the present invention.
Embodiment 3: this buccal tablet for clearing and moistening throat constituent and percentage by weight are: Semen Capparis kernel extract 15%, microcrystalline Cellulose 5%, maltodextrin 67%, Mentholum 5%, Borneolum Syntheticum 5%, distilled water 3%.
The manufacture method of Semen Capparis kernel extract powder in described buccal tablet for clearing and moistening throat:
1, get fresh mature Semen Capparis fruit, obtain Semen Capparis kernel after peelling off shell and mesochite, Semen Capparis kernel is placed in refrigerator, regulate temperature to be 4 DEG C of preservations, for subsequent use;
2, take out Semen Capparis kernel, by pulverizing, obtaining fineness after sieving is 120 object Semen Capparis kernel powder;
3, step 2 gained Semen Capparis kernel fine powder is layered on bottom microwave oven special box, Semen Capparis kernel powder thickness is made to remain on 5 millimeter, the sealing of microwave oven special box is placed in Microwave Extraction Apparatus and carries out microwave radiation processing, wherein, the microwave radiation processing time is set as 60 seconds, and microwave irradiation power is set as 15 watts/gram;
4, the Semen Capparis kernel powder after step 3 microwave radiation enzyme denaturing is taken out, be placed in ice-water bath and be cooled to room temperature, namely obtain the Semen Capparis kernel powder after microwave radiation enzyme denaturing;
5, by gained Semen Capparis kernel powder after step 4 microwave radiation enzyme denaturing with 60 DEG C of hot water of its quality 3 times and keep water temperature soak 3h, extracting solution 120 object screen filtrations, collect filtrate, filtering residue squeezer squeezes, squeeze the juice and to mix with filtrate, then use filter press or rotary drum filter to carry out fine straining, obtain fine straining liquid;
6, step 5 fine straining liquid is carried out vacuum concentration, make the volume after concentrating be about before concentrating 1/3 ~ 1/2, vacuum is 0.01 ~ 0.03MPa, and temperature is 60 ~ 70 DEG C;
7, directly spray in the spray tank that cryogen (liquid nitrogen) is housed with the concentrated solution that above-mentioned steps 6 to be concentrated gained by the method for pressure atomization, wherein, the atomizing pressure of pressure atomization is 6 MPa, and the concentrated solution containing Semen Capparis extract is directly frozen into small solid particles in spray tank;
8, the small solid particles of gained of step 7 being sprayed, freeze all is transferred in vacuum freeze drier and is carried out vacuum lyophilization, vacuum drying vacuum 10 Pa, first
-40 DEG C of dryings 4 hours, then in 12 hours temperature from
-40 DEG C rise to 25 DEG C, and namely last 25 DEG C of dryings obtain Semen Capparis kernel extract for 4 hours;
the manufacture method of described buccal tablet for clearing and moistening throat:
1, get described Mentholum, Borneolum Syntheticum by pulverizing, obtaining fineness after sieving is 120 object Mentholums, borneol powder;
2, described Semen Capparis kernel extract, microcrystalline Cellulose, maltodextrin, Mentholum, Borneolum Syntheticum, distilled water are poured in mixer, abundant mix homogeneously;
3, the material tablet machine mixed is carried out tabletting by 1g/ sheet, obtain buccal tablet for clearing and moistening throat of the present invention.
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from spirit of the present invention and principle, substitute, combine, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.
Claims (5)
1. a buccal tablet for clearing and moistening throat, is characterized in that: constituent and mass percent are Semen Capparis kernel extract 10% ~ 15%, food adhesive 5% ~ 15%, filler 57% ~ 77%, Mentholum 3% ~ 5%, Borneolum Syntheticum 3% ~ 5%, distilled water 2% ~ 3%.
2. buccal tablet for clearing and moistening throat according to claim 1, is characterized in that: food adhesive is microcrystalline Cellulose.
3. buccal tablet for clearing and moistening throat according to claim 1 and 2, is characterized in that: filler is maltodextrin.
4. buccal tablet for clearing and moistening throat according to claim 3, is characterized in that the preparation method of Semen Capparis kernel extract is as follows:
(1) get fresh mature Semen Capparis fruit, obtain Semen Capparis kernel after peelling off shell and mesochite, pulverize, obtaining fineness after sieving is 80 ~ 120 object Semen Capparis kernel powder;
(2) step (1) Semen Capparis kernel powder is laid in the powder bed of thickness 4-6mm, is placed in Microwave Extraction Apparatus and carries out microwave radiation processing; Wherein, the microwave radiation processing time is 60 ~ 70 seconds, and microwave irradiation power is 10 ~ 15 watts/gram;
(3) the Semen Capparis kernel powder after step (2) microwave radiation enzyme denaturing is taken out, be cooled to room temperature, namely obtain the Semen Capparis kernel powder after microwave radiation enzyme denaturing;
(4) 60 DEG C ~ 70 DEG C hot water constant temperatures of its quality 3 ~ 4 times of the Semen Capparis kernel powder after step (3) microwave radiation enzyme denaturing are soaked 3 ~ 4h, filter, collect filtrate, filtering residue squeezer squeezes, squeeze the juice and to merge with filtrate, then use filter press or rotary drum filter to carry out fine straining, obtain fine straining liquid;
(5) fine straining liquid is carried out vacuum concentration, make concentrated after volume be condensate precursor long-pending 1/3 ~ 1/2, vacuum is 0.01 ~ 0.03MPa, and temperature is 60 ~ 70 DEG C;
(6) by the method for pressure atomization step (5) concentrated solution directly sprayed into and be equipped with in the spray tank of cryogen; Wherein, the atomizing pressure of pressure atomization is 6 MPa, and the concentrated solution containing Semen Capparis kernel extract is directly frozen into small solid particles in spray tank;
(7) small solid particles of gained of step (6) being sprayed, freezed carries out vacuum lyophilization, vacuum drying vacuum 10 Pa, first
-40 DEG C of dryings 4 hours, then in 12 hours temperature from
-40 DEG C rise to 25 DEG C, and namely last 25 DEG C of dryings obtain Semen Capparis kernel extract for 4 hours.
5. buccal tablet for clearing and moistening throat according to claim 3, is characterized in that: cryogen is the one in liquid nitrogen, liquid carbon dioxide.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107467571A (en) * | 2017-08-23 | 2017-12-15 | 湖南胖哥食品有限责任公司 | Betel nut additive and preparation method thereof and betel nut product and preparation method thereof |
| CN109349633A (en) * | 2018-11-16 | 2019-02-19 | 云南瀚博生物科技开发有限公司 | A kind of functional food and preparation method thereof for alleviating cigarette throat discomfort |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101773560B (en) * | 2010-01-27 | 2011-07-27 | 昆明中药厂有限公司 | Method for testing quality of Nguyen supernatant pills |
| CN103463498B (en) * | 2013-09-25 | 2015-04-15 | 倪承香 | Traditional Chinese medicine preparation for treating sphagitis |
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2015
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107467571A (en) * | 2017-08-23 | 2017-12-15 | 湖南胖哥食品有限责任公司 | Betel nut additive and preparation method thereof and betel nut product and preparation method thereof |
| CN107467571B (en) * | 2017-08-23 | 2021-04-02 | 湖南胖哥食品有限责任公司 | Areca nut additive and preparation method thereof, and areca nut product and preparation method thereof |
| CN109349633A (en) * | 2018-11-16 | 2019-02-19 | 云南瀚博生物科技开发有限公司 | A kind of functional food and preparation method thereof for alleviating cigarette throat discomfort |
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