CN105004864B - 用于肾损伤和肾衰竭的诊断及预后方法和组合物 - Google Patents

用于肾损伤和肾衰竭的诊断及预后方法和组合物 Download PDF

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Publication number
CN105004864B
CN105004864B CN201510401130.0A CN201510401130A CN105004864B CN 105004864 B CN105004864 B CN 105004864B CN 201510401130 A CN201510401130 A CN 201510401130A CN 105004864 B CN105004864 B CN 105004864B
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subject
concentration
measure concentration
threshold value
possibility
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CN105004864A (zh
Inventor
J·安德贝里
J·格雷
P·麦克弗森
K·中村
J·P·坎普夫
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Astute Medical Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • G01N2333/7452Thrombomodulin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81Protease inhibitors
    • G01N2333/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201510401130.0A 2009-09-18 2010-09-17 用于肾损伤和肾衰竭的诊断及预后方法和组合物 Expired - Fee Related CN105004864B (zh)

Applications Claiming Priority (7)

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US24399509P 2009-09-18 2009-09-18
US24400009P 2009-09-18 2009-09-18
US61/243,995 2009-09-18
US61/244,000 2009-09-18
US25463609P 2009-10-23 2009-10-23
US61/254,636 2009-10-23
CN201080043037.2A CN102576012B (zh) 2009-09-18 2010-09-17 用于肾损伤和肾衰竭的诊断及预后方法和组合物

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CN105004864A CN105004864A (zh) 2015-10-28
CN105004864B true CN105004864B (zh) 2017-11-03

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CN201080043037.2A Expired - Fee Related CN102576012B (zh) 2009-09-18 2010-09-17 用于肾损伤和肾衰竭的诊断及预后方法和组合物

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US (2) US20130045494A1 (enExample)
EP (2) EP2470904A4 (enExample)
JP (3) JP2013513086A (enExample)
CN (2) CN105004864B (enExample)
AU (2) AU2010295512B2 (enExample)
CA (1) CA2773905A1 (enExample)
EA (1) EA201290106A1 (enExample)
MX (1) MX2012003168A (enExample)
NZ (2) NZ598741A (enExample)
WO (1) WO2011035097A1 (enExample)

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ES2721907T3 (es) * 2011-08-26 2019-08-06 Astute Medical Inc Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal
JP6532460B2 (ja) * 2013-07-26 2019-06-19 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 患者モニタリングシステムに関する臨床規則及び規定のコンピュータ化及び視覚化
GB201501597D0 (en) * 2015-01-30 2015-03-18 Randox Lab Ltd Thrombomodulin
CN108271422A (zh) 2015-06-25 2018-07-10 株式会社国际电气通信基础技术研究所 基于器官间串扰系统的预测装置及预测程序
WO2017130985A1 (ja) * 2016-01-29 2017-08-03 株式会社国際電気通信基礎技術研究所 腎機能の評価装置、腎疾患の合併症の発症の予測装置、およびリン摂取量推定装置
JP6432962B2 (ja) 2016-03-29 2018-12-05 株式会社国際電気通信基礎技術研究所 腎機能低下、慢性腎疾患及び腎不全からなる群から選択される少なくとも一種の疾患を予防、又は治療するための有効成分の候補物質のスクリーニング方法
JP6332780B2 (ja) 2016-03-29 2018-05-30 株式会社国際電気通信基礎技術研究所 医薬組成物又は食品組成物、及び有効成分の体内での効果の評価方法

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Also Published As

Publication number Publication date
CN105004864A (zh) 2015-10-28
EP2470904A1 (en) 2012-07-04
US20190250170A1 (en) 2019-08-15
JP2013513086A (ja) 2013-04-18
CN102576012B (zh) 2015-07-15
CN102576012A (zh) 2012-07-11
JP6403712B2 (ja) 2018-10-10
EA201290106A1 (ru) 2012-12-28
JP2015129764A (ja) 2015-07-16
EP2470904A4 (en) 2013-05-01
AU2015200953A1 (en) 2015-03-12
HK1212774A1 (zh) 2016-06-17
NZ612673A (en) 2014-10-31
HK1167889A1 (zh) 2012-12-14
US20130045494A1 (en) 2013-02-21
JP2016176953A (ja) 2016-10-06
MX2012003168A (es) 2012-05-08
CA2773905A1 (en) 2011-03-24
AU2010295512B2 (en) 2014-12-18
AU2010295512A1 (en) 2012-04-05
WO2011035097A1 (en) 2011-03-24
EP3299821A1 (en) 2018-03-28
NZ598741A (en) 2013-07-26

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