CN104998219A - Medicament for treating vital-qi deficiency and blood stasis (kidney deficiency) type mammary gland hyperplasia - Google Patents
Medicament for treating vital-qi deficiency and blood stasis (kidney deficiency) type mammary gland hyperplasia Download PDFInfo
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- CN104998219A CN104998219A CN201510546117.4A CN201510546117A CN104998219A CN 104998219 A CN104998219 A CN 104998219A CN 201510546117 A CN201510546117 A CN 201510546117A CN 104998219 A CN104998219 A CN 104998219A
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Abstract
The invention discloses a medicament for treating vital-qi deficiency and blood stasis (kidney deficiency) type mammary gland hyperplasia. The medicament is prepared from the following raw materials in parts by weight: 15 to 25 parts of radix rehmanniae preparata, 12 to 18 parts of Chinese angelica, 12 to 18 parts of white paeony root, 10 to 20 parts of nutgrass galingale rhizome, 6 to 10 parts of cuscuta chinensis, 6 to 10 parts of epimedium brevicornu maxim, 12 to 18 parts of curculigo orchioides, 6 to 10 parts of deer-horn glue, 10 to 20 parts of kelp, 10 to 20 parts of aiomatic turmeric root-tuber, 10 to 20 parts of semen vaccariae, 12 to 18 parts of dried tangerine peel and 12 to 18 parts of tuckahoe. According to the medicament for treating the vital-qi deficiency and blood stasis (kidney deficiency) type mammary gland hyperplasia, disclosed by the invention, the thirteen kinds of natural Chinese medicines are selected for scientifically matching; the formula is simple; all active pharmaceutical ingredients synergistically act to achieve the effects of regulating thoroughfare and conception vessels, softening hardness to dissipate stagnation and warming yang and invigorating kidney; the medicament is prepared by adopting a simple method, and has the advantages of quick response, no toxic or side effect, convenience in administration and low cost.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically one is used for the treatment of the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy.
Background technology
Cyclomastopathy is the common mastopathy of women.The glossology of primary disease is very chaotic, has another name called cyclomastopathy, mammary dysplasia, Fibrocystic disease etc.Once be called chronic cystic mastitis, in fact primary disease NIP sexually revises in the past, thus should not apply.The feature of primary disease is the hypertrophy of mammary gland constituent, and structure, quantity and tissue morphology show exception, therefore is called cystic hyperplasia or mammary dysplasia.The height of its morbidity, scope are extensively, the cycle is near, painful big, have had a strong impact on the working and learning of numerous women, have reduced the quality of life.
The traditional Chinese medical science is to cyclomastopathy dialectical point of four kinds of pattern of syndrome: caused by hepatic stagnation qi stagnation, blood stasis gather type, phlegm-damp internal resistance type, weakened body resistance blood stasis (suffering from a deficiency of the kidney) type four kinds of sick types.Wherein weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy shows as, and breast has lump, and premenstrual or menstrual period, pain increased the weight of, and alleviates or disappear after row, prolong after menstrual period are many, dysmenorrhoea is not acute, hypomenorrhea, and body is tired unable, soreness of waist cold extremities, few abdomen fear of cold, with the passing of time losing the person of controlling, can there is canceration in minority.
At present, formula and the various medicine of blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy that clinical treatment is weakened body resistance have a lot, but comparatively speaking, the cycle for the treatment of is partially long, takes effect not obvious, also there is sensory difference to a certain extent simultaneously.
Summary of the invention
The object of the invention is for people provide one to have Chong and Ren Meridians regulating, hard masses softening and resolving, the medicine of the weakened body resistance blood stasis for the treatment of (suffering from a deficiency of the kidney) the type cyclomastopathy of effect of temperature male wind-supplying kidney.
The technical scheme realizing the object of the invention is:
One is used for the treatment of the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, and the raw material primarily of following weight parts proportioning is made:
Radix Rehmanniae Preparata 15-25 part, Radix Angelicae Sinensis 12-18 part, Radix Paeoniae Alba 12-18 part, Rhizoma Cyperi 10-20 part, Semen Cuscutae 6-10 part, Herba Epimedii 6-10 part, Rhizoma Curculiginis 12-18 part, Colla cornus cervi 6-10 part, Thallus Laminariae (Thallus Eckloniae) 10-20 part, Radix Curcumae 10-20 part, SEMEN VACCARIAE 10-20 part, Pericarpium Citri Reticulatae 12-18 part, Poria 12-18 part.
One is used for the treatment of the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, and optimum weight part proportioning of each raw material is:
Radix Rehmanniae Preparata 20 parts, Radix Angelicae Sinensis 15 parts, the Radix Paeoniae Alba 15 parts, Rhizoma Cyperi 15 parts, Semen Cuscutae 8 parts, Herba Epimedii 8 parts, Rhizoma Curculiginis 15 parts, Colla cornus cervi 8 parts, Thallus Laminariae (Thallus Eckloniae) 15 parts, Radix Curcumae 15 parts, SEMEN VACCARIAE 15 parts, Pericarpium Citri Reticulatae 15 parts, 15 parts, Poria.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 35-40min, merges decoction liquor, filter and remove residue, it is the extractum of 1.10-1.30 that filtrate is concentrated into relative density at 60-65 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
In the present invention, pharmacology, effect of each crude drug are as follows:
Radix Rehmanniae Preparata: be the tuber of scrophulariaceae rehmannia glutinosa plant (formal name used at school: Rehmannia glutinosa), have another name called Radix Rehmanniae Preparata or throw oneself on the ground, forming through Processing methods.Usually with wine, Fructus Amomi, Pericarpium Citri Reticulatae for adjuvant is through repeatedly steaming solarization, to inside and outside darkish complexion glossy, quality softness is sticky.Section use, or parch to black is used.Cure mainly: blood tiger is sallow; Dizzy cardiopalmus; Menoxenia; Collapse more than; Hepatic and renal YIN deficiency; Hectic fever night sweat; Seminal emission sexual impotence; Infertility; Soreness of the waist and knees; Hiccough and deaf; The head is dim-sighted; Early whitening of beard and hair; Quench one's thirst; Constipation; To suffer from a deficiency of the kidney dyspnea with rapid and short breath.
Radix Angelicae Sinensis: formal name used at school Angelica sinensis, cures mainly all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
The Radix Paeoniae Alba: cool in nature, bitter in the mouth acid, is slightly cold, and has the effects such as easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receipts antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.
Rhizoma Cyperi: there is resolving depression of regulating the flow of vital energy; Menstruction regulating and pain relieving; Antiabortive effect.Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Semen Cuscutae: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.Suffer from a deficiency of the kidney rush down for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen; Externally treating leucoderma.
Herba Epimedii: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Rhizoma Curculiginis: the kidney warming sun, strengthening bone and muscle.Control sexual impotence cold sperm, urinary incontinence, metrorrhagia, trusted subordinate's cold type of pain, cold arthralgia of loins and legs, carbuncle, scrofula, yang deficiency cold diarrhea.
Colla cornus cervi: temperature compensation Liver and kidney, beneficial intensive culture blood.For sexual impotence spermatorrhea, the acid of waist knee joint is cold, and asthenia is won thin, and metrostaxis, hematuria of having blood in stool, carbuncle of yin nature swells and ache.
Thallus Laminariae (Thallus Eckloniae): the merit having hard masses softening and resolving, detumescencing diuresis, relaxing the bowels with lubricant drugs expectorant, bronchitis, pulmonary tuberculosis swollen for goiter, lymphonodi cervicales, cough and senile cataract etc., also try out in Therapeutic cancer clinically.
Radix Curcumae: the use with regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire.The how raw use of the general disease of Radix Curcumae, waking up the patient from unconsciousness by dissipating phlegm Yi Fanshui fries.
SEMEN VACCARIAE: there is promoting the circulation of blood and stimulate the menstrual flow, expedite the emergence of stimulating milk secretion, effect of detumescence sore.Control women's amenorrhea, galactostasis, difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.
Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach.Abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool.Phlegm-damp stops up the cough and asthma of lung.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Poria: formal name used at school: Poria cocos (Schw.) Wolf, another name: Fu Tu, Poria, Fu Ling, Fu Ling, volt Tu, pine fat, Poria, Fu rabbit, loose potato, Masson Pine potato, Song Ling.Mild in medicine property and, dampness removing and do not hinder healthy energy.Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, have loose bowels, pass out semen, stranguria with turbid discharge, palpitation with fear, the disease such as forgetful.
13 kinds of natural Chinese medicine scientific compatibility chosen by the medicine that the present invention is used for the treatment of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, formula is simple, each crude drug synergism plays the effect of Chong and Ren Meridians regulating, hard masses softening and resolving, temperature male wind-supplying kidney, instant effect, have no side effect, and its preparation method is simple, taking convenience, cost is low.
Detailed description of the invention
Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.
Embodiment 1
One is used for the treatment of the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, and the proportioning of crude drug is:
Radix Rehmanniae Preparata 15kg, Radix Angelicae Sinensis 12kg, Radix Paeoniae Alba 12kg, Rhizoma Cyperi 10kg, Semen Cuscutae 6kg, Herba Epimedii 6kg, Rhizoma Curculiginis 12kg, Colla cornus cervi 6kg, Thallus Laminariae (Thallus Eckloniae) 10kg, Radix Curcumae 10kg, SEMEN VACCARIAE 10kg, Pericarpium Citri Reticulatae 12kg, Poria 12kg.
Preparation method is as follows: be placed in container by the mixing of above-mentioned raw materials medicine, then add the soak by water 3 times of material quantity weight 10 times, decoct 35min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.10 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make tablet, every sheet 0.2g.
Embodiment 2
One is used for the treatment of the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, and the proportioning of crude drug is:
Radix Rehmanniae Preparata 20kg, Radix Angelicae Sinensis 15kg, Radix Paeoniae Alba 15kg, Rhizoma Cyperi 15kg, Semen Cuscutae 8kg, Herba Epimedii 8kg, Rhizoma Curculiginis 15kg, Colla cornus cervi 8kg, Thallus Laminariae (Thallus Eckloniae) 15kg, Radix Curcumae 15kg, SEMEN VACCARIAE 15kg, Pericarpium Citri Reticulatae 15kg, Poria 15kg.
Preparation method is as follows: be placed in container by the mixing of above-mentioned raw materials medicine, then add the soak by water 3 times of material quantity weight 15 times, decoct 35min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make tablet, every sheet 0.3g.
Embodiment 3
One is used for the treatment of the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, and the proportioning of crude drug is:
Radix Rehmanniae Preparata 20kg, Radix Angelicae Sinensis 15kg, Radix Paeoniae Alba 15kg, Rhizoma Cyperi 15kg, Semen Cuscutae 8kg, Herba Epimedii 8kg, Rhizoma Curculiginis 15kg, Colla cornus cervi 8kg, Thallus Laminariae (Thallus Eckloniae) 15kg, Radix Curcumae 15kg, SEMEN VACCARIAE 15kg, Pericarpium Citri Reticulatae 15kg, Poria 15kg.
Preparation method is as follows: be placed in container by the mixing of above-mentioned raw materials medicine, then add the soak by water 3 times of material quantity weight 15 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 65 DEG C, add adjuvant, make pill, every 0.3g.
Embodiment 4
One is used for the treatment of the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, and the proportioning of crude drug is:
Radix Rehmanniae Preparata 25kg, Radix Angelicae Sinensis 18kg, Radix Paeoniae Alba 18kg, Rhizoma Cyperi 20kg, Semen Cuscutae 10kg, Herba Epimedii 10kg, Rhizoma Curculiginis 18kg, Colla cornus cervi 10kg, Thallus Laminariae (Thallus Eckloniae) 20kg, Radix Curcumae 20kg, SEMEN VACCARIAE 20kg, Pericarpium Citri Reticulatae 18kg, Poria 18kg.
Preparation method is as follows: be placed in container by the mixing of above-mentioned raw materials medicine, then add the soak by water 3 times of material quantity weight 20 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 65 DEG C, add adjuvant, make pill, every 0.4g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 160 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 25-45 year, be divided into 4 groups at random, often organize 40 example, be respectively experimental group 1-4 group.
Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 3 times, and each 5 slices/for oral administration, within one week, be a course for the treatment of, the course for the treatment of is 2 weeks.Wherein effective 150 examples, effective 153 examples, cure 149 examples, invalid 7 examples, cure rate 93%, effective percentage 96%.
Claims (3)
1. be used for the treatment of a medicine for weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, it is characterized in that: be made up of the raw material of following weight parts proportioning:
Radix Rehmanniae Preparata 15-25 part, Radix Angelicae Sinensis 12-18 part, Radix Paeoniae Alba 12-18 part, Rhizoma Cyperi 10-20 part, Semen Cuscutae 6-10 part, Herba Epimedii 6-10 part, Rhizoma Curculiginis 12-18 part, Colla cornus cervi 6-10 part, Thallus Laminariae (Thallus Eckloniae) 10-20 part, Radix Curcumae 10-20 part, SEMEN VACCARIAE 10-20 part, Pericarpium Citri Reticulatae 12-18 part, Poria 12-18 part.
2. one according to claim 1 is used for the treatment of the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, it is characterized in that: optimum weight part proportioning of each raw material is:
Radix Rehmanniae Preparata 20 parts, Radix Angelicae Sinensis 15 parts, the Radix Paeoniae Alba 15 parts, Rhizoma Cyperi 15 parts, Semen Cuscutae 8 parts, Herba Epimedii 8 parts, Rhizoma Curculiginis 15 parts, Colla cornus cervi 8 parts, Thallus Laminariae (Thallus Eckloniae) 15 parts, Radix Curcumae 15 parts, SEMEN VACCARIAE 15 parts, Pericarpium Citri Reticulatae 15 parts, 15 parts, Poria.
3. one according to claim 1 is used for the medicine of weakened body resistance blood stasis (suffering from a deficiency of the kidney) type cyclomastopathy, it is characterized in that: preparation method is as follows: take each crude drug by weight ratio, add mixing and be placed in container, then add material quantity weight 10-20 soak by water doubly 3 times, decoct 35-40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.10-1.30 that filtrate is concentrated into relative density at 60-65 DEG C, adds adjuvant, make corresponding dosage form, to obtain final product.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177794A (en) * | 2016-08-29 | 2016-12-07 | 黄佩丽 | For treating the medicine of blood stasis type cyclomastopathy |
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| JP2010180154A (en) * | 2009-02-05 | 2010-08-19 | Fancl Corp | Estrogen substitute composition |
| CN104547394A (en) * | 2014-12-22 | 2015-04-29 | 江西中医药大学 | Traditional Chinese medicine composition for treating hyperplasia of mammary glands |
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2015
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010180154A (en) * | 2009-02-05 | 2010-08-19 | Fancl Corp | Estrogen substitute composition |
| CN104547394A (en) * | 2014-12-22 | 2015-04-29 | 江西中医药大学 | Traditional Chinese medicine composition for treating hyperplasia of mammary glands |
Non-Patent Citations (2)
| Title |
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| 惠彩莲等: "辨证施治治疗乳腺增生症60例", 《延边大学学报》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177794A (en) * | 2016-08-29 | 2016-12-07 | 黄佩丽 | For treating the medicine of blood stasis type cyclomastopathy |
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Application publication date: 20151028 |