CN105106580A - Medicine for treating osteoporosis - Google Patents
Medicine for treating osteoporosis Download PDFInfo
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- CN105106580A CN105106580A CN201510653920.8A CN201510653920A CN105106580A CN 105106580 A CN105106580 A CN 105106580A CN 201510653920 A CN201510653920 A CN 201510653920A CN 105106580 A CN105106580 A CN 105106580A
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Abstract
The invention discloses medicine for treating osteoporosis. The medicine is prepared from the following raw materials in parts by weight: 3-8 parts of rhizoma cibotii, 5-10 parts of rhizoma curculiginis, 10-15 parts of radix morindae officinalis, 10-15 parts of rhizoma anemarrhenae, 5-10 parts of cortex phellodendri, 3-8 parts of rhizoma drynariae, 5-10 parts of fructus psoraleae, 10-15 parts of radix dipsaci, 5-10 parts of caulis spatholobi, 8-12 parts of herba epimedii, 5-8 parts of mastic, 5-8 parts of myrrh, 10-15 parts of burdock, 10-15 parts of ligusticum wallichii and 10-15 parts of angelica sinensis. According to the medicine for treating osteoporosis, 15 natural traditional Chinese medicines are selected and scientifically combined, the formula is simple, the raw medicinal materials cooperate to achieve the efficacies of nourishing kidney and spleen, enriching blood and benefiting qi, the medicine takes effect quickly, treats both symptoms and root causes, and is free of toxic and side effects, the preparation method is simple, the medicine is convenient to take, the cost is low, and the effective rate reaches 93% or above.
Description
Technical field
The present invention relates to Chinese medicine, specifically a kind of medicine being used for the treatment of osteoporosis.
Background technology
Osteoporosis (osteoporosis) is a kind of systemic osteopathia, it is characterized in that bone amount declines and the fine structure of bone destroys, the fragility showing as bone increases, and the danger of thus fracturing greatly increases, even also easily fracture in slight wound or atraumatic situation.Osteoporosis is a kind of multifactor caused chronic disease.Before fracture occurs, usually without Special Clinical Manifestation.This sick women, more than male, is common in postmenopausal women and old people.According to statistics, the whole world has suffers from osteoporosis more than 300,000,000 people, and its sickness rate has leapt to various common disease prostatitis, the world, is acknowledged as in the world that sickness rate is the highest, mortality rate is the highest, consume one of maximum disease.With China's aged tendency of population process, osteoporosis has become one of the most serious problem of harm China population publilc health.
Osteoporosis is the name of disease of western medicine, and its main manifestations is osteodynia, height shortens, bow-backed deformity, fracture etc.Although not this name of disease in the ancient books and records of Chinese medicine, but show similar discussion, belong to the category such as " atrophic debility of bones ", " rheumatism involving the bone ", " bone is withered ", " bone exhaustion ", " asthenia ".About the pathogen and pathology of tcm of osteoporosis, each doctor has oneself discussion.Viewpoint more consistent is at present: the generation of osteoporosis and kidney,liver,spleen etc. have relation, and wherein deficiency of the kidney is main, and the liver failing to maintain the normal flow of QI is crucial, and insufficiency of the spleen is auxiliary.
Present is main mainly with western medicine, but side effect is comparatively large, and easily recurs, and can not effect a radical cure, cause certain burden to patient's economy and physiology.And the therapeutic efficiency of some current Chinese medicines is also not satisfactory, treatment cycle is long, and curative effect is not remarkable.
Summary of the invention
The object of this invention is to provide the medicine being used for the treatment of osteoporosis that a kind of good effect, cost are low, have no side effect.
The technical scheme realizing the object of the invention is:
Be used for the treatment of a medicine for osteoporosis, be made up of the raw material of following weight parts proportioning:
Rhizoma Cibotii 3-8 part, Rhizoma Curculiginis 5-10 part, Radix Morindae Officinalis 10-15 part, Rhizoma Anemarrhenae 10-15 part, Cortex Phellodendri 5-10 part, Rhizoma Drynariae 3-8 part, Fructus Psoraleae 5-10 part, Radix Dipsaci 10-15 part, Caulis Spatholobi 5-10 part, Herba Epimedii 8-12 part, Olibanum 5-8 part, Myrrha 5-8 part, Fructus Arctii 10-15 part, Rhizoma Chuanxiong 10-15 part, Radix Angelicae Sinensis 10-15 part.
The above-mentioned medicine being used for the treatment of osteoporosis, optimum weight part proportioning of each raw material is:
Rhizoma Cibotii 6 parts, Rhizoma Curculiginis 8 parts, Radix Morindae Officinalis 12 parts, the Rhizoma Anemarrhenae 12 parts, Cortex Phellodendri 8 parts, Rhizoma Drynariae 6 parts, Fructus Psoraleae 8 parts, Radix Dipsaci 12 parts, Caulis Spatholobi 8 parts, Herba Epimedii 10 parts, Olibanum 6 parts, Myrrha 6 parts, Fructus Arctii 12 parts, Rhizoma Chuanxiong 12 parts, Radix Angelicae Sinensis 12 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 40-45min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.40 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
In the present invention, pharmacology, effect of each crude drug are as follows:
Rhizoma Cibotii: wind-damp dispelling, invigorating the liver and kidney, strong waist knee joint.For rheumatic arthralgia, soreness of the waist and knees, weakness of the lower extremities.
Rhizoma Curculiginis: the kidney warming sun is strong; Dispel cold-damp.Main sexual impotence cold sperm; Urinary incontinence; Coldness and pain in the epigastrium; Soreness of waist and knee joint; Muscles and bones is weak; Lower limb contracture; Climacteric syndrome.
Radix Morindae Officinalis: there is kidney-replenishing, bone and muscle strengthening, effect of wind-damp dispelling.Be usually used in for impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.
The Rhizoma Anemarrhenae: property bitter cold, has nourishing YIN to lower pathogenic fire, moisturizes laxation, the effect of sharp defecation.Gunpowder under genus heat clearing away, cures mainly: epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst.
Cortex Phellodendri: have heat clearing and damp drying, pathogenic fire purging removes steams, effect of detoxification sore treatment.For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Rhizoma Drynariae: the kidney invigorating bone strengthening, continues and hinders pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.
Fructus Psoraleae: kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, lumbago due to renal deficiency, frequent micturition, bed-wetting, kidney leaks, warming spleen and stopping diarrha, helping inspiration to relieve asthma.Cure mainly impotence due to deficiency of the kidney, soreness of the waist and knees cold type of pain, emission due to deficiency of the kidney, the enuresis, frequent micturition etc.
Radix Dipsaci: the effect having invigorating the liver and kidney, bone and muscle strengthening, continuous injured, only metrorrhagia, can be used for the disease for the treatment of soreness of the waist and knees, rheumatic arthralgia, metrorrhagia, vaginal bleeding during pregnancy, injury from falling down.Wherein prepared RADIX DIPSACI with yellow rice wine is used for rheumatic arthralgia, injury from falling down, and prepared RADIX DIPSACI with salt solution is used for soreness of the waist and knees.
Caulis Spatholobi: there is blood circulation promoting and enriching, menstruction regulating and pain relieving, effect of relaxing muscles and tendons and activating QI and blood in the collateral.For menoxenia, dysmenorrhea, amenorrhea, rheumatic arthralgia, paralysis and numbness, blood deficiency and yellow complexion.
Herba Epimedii: cure mainly impotence and premature ejaculation, pain in the low back and legs, numb limbs and tense tendons, hemiplegia, neurasthenia, forgetful, tinnitus, dizzy disease such as grade.Herba Epimedii is Chinese conventional Chinese medicine.
Olibanum: blood-activating and qi-promoting pain relieving, detumescence and promoting granulation.For obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, lump in the abdomen is suffered from abdominal pain, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection.
Myrrha: there is dissipating blood stasis analgesic therapy, effect of detumescence and promoting granulation.Be usually used in obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation ， mass in the abdomen is suffered from abdominal pain, rheumatic arthralgia, traumatic injury, the treatment of the diseases such as carbuncle skin infection.
Fructus Arctii: there is treatment diabetes, hypertension, hyperlipidemia, the effect such as anticancer.Can blood sugar lowering, blood pressure lowering, blood fat, Cure for insomnia, improve the effects such as body immunity.
Rhizoma Chuanxiong: activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Angelicae Sinensis: having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.Be usually used in blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
The present invention treats the medicine of osteoporosis, and choose 15 kinds of natural Chinese medicine scientific compatibility, formula is simple, each crude drug synergism plays the effect of kidney and spleen invigorating, blood yiqi, instant effect, treating both the principal and secondary aspects of a disease, have no side effect, and its preparation method is simple, taking convenience, cost is low.
Detailed description of the invention
Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.
Embodiment 1
Be used for the treatment of a medicine for osteoporosis, be made up of the raw material of following weight parts proportioning:
Rhizoma Cibotii 3kg, Rhizoma Curculiginis 5kg, Radix Morindae Officinalis 10kg, Rhizoma Anemarrhenae 10kg, Cortex Phellodendri 5kg, Rhizoma Drynariae 3kg, Fructus Psoraleae 5kg, Radix Dipsaci 10kg, Caulis Spatholobi 5kg, Herba Epimedii 8kg, Olibanum 5kg, Myrrha 5kg, Fructus Arctii 10kg, Rhizoma Chuanxiong 10kg, Radix Angelicae Sinensis 10kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 10 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 50 DEG C, add adjuvant, make tablet, every sheet 0.1g.
Embodiment 2
Be used for the treatment of a medicine for osteoporosis, be made up of the raw material of following weight parts proportioning:
Rhizoma Cibotii 6kg, Rhizoma Curculiginis 8kg, Radix Morindae Officinalis 12kg, Rhizoma Anemarrhenae 12kg, Cortex Phellodendri 8kg, Rhizoma Drynariae 6kg, Fructus Psoraleae 8kg, Radix Dipsaci 12kg, Caulis Spatholobi 8kg, Herba Epimedii 10kg, Olibanum 6kg, Myrrha 6kg, Fructus Arctii 12kg, Rhizoma Chuanxiong 12kg, Radix Angelicae Sinensis 12kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 15 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 52 DEG C, add adjuvant, make tablet, every sheet 0.2g.
Embodiment 3
Be used for the treatment of a medicine for osteoporosis, be made up of the raw material of following weight parts proportioning:
Rhizoma Cibotii 8kg, Rhizoma Curculiginis 10kg, Radix Morindae Officinalis 15kg, Rhizoma Anemarrhenae 15kg, Cortex Phellodendri 10kg, Rhizoma Drynariae 8kg, Fructus Psoraleae 10kg, Radix Dipsaci 15kg, Caulis Spatholobi 10kg, Herba Epimedii 12kg, Olibanum 8kg, Myrrha 8kg, Fructus Arctii 15kg, Rhizoma Chuanxiong 15kg, Radix Angelicae Sinensis 15kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 18 times, decoct 42min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 58 DEG C, add adjuvant, make pill, every 0.4g.
Embodiment 4
Be used for the treatment of a medicine for osteoporosis, be made up of the raw material of following weight parts proportioning:
Rhizoma Cibotii 8kg, Rhizoma Curculiginis 10kg, Radix Morindae Officinalis 15kg, Rhizoma Anemarrhenae 15kg, Cortex Phellodendri 10kg, Rhizoma Drynariae 8kg, Fructus Psoraleae 10kg, Radix Dipsaci 15kg, Caulis Spatholobi 10kg, Herba Epimedii 12kg, Olibanum 8kg, Myrrha 8kg, Fructus Arctii 15kg, Rhizoma Chuanxiong 15kg, Radix Angelicae Sinensis 15kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 20 times, decoct 45min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.40 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make pill, every 0.5g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 400 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 50-70 year, be divided into 4 groups at random, often group be 100 example, be respectively experimental group 1-4 group.
Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 3 times, each 3 slices/for oral administration, within 10 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.Wherein effective 370 examples, effective 372 examples, cure 358 examples, invalid 28 examples, cure rate 89.5%, effective percentage 93%.
Claims (3)
1. be used for the treatment of a medicine for osteoporosis, it is characterized in that: be made up of the raw material of following weight parts proportioning:
Rhizoma Cibotii 3-8 part, Rhizoma Curculiginis 5-10 part, Radix Morindae Officinalis 10-15 part, Rhizoma Anemarrhenae 10-15 part, Cortex Phellodendri 5-10 part, Rhizoma Drynariae 3-8 part, Fructus Psoraleae 5-10 part, Radix Dipsaci 10-15 part, Caulis Spatholobi 5-10 part, Herba Epimedii 8-12 part, Olibanum 5-8 part, Myrrha 5-8 part, Fructus Arctii 10-15 part, Rhizoma Chuanxiong 10-15 part, Radix Angelicae Sinensis 10-15 part.
2. a kind of medicine being used for the treatment of osteoporosis according to claim 1, is characterized in that: optimum weight part proportioning of each raw material is:
Rhizoma Cibotii 6 parts, Rhizoma Curculiginis 8 parts, Radix Morindae Officinalis 12 parts, the Rhizoma Anemarrhenae 12 parts, Cortex Phellodendri 8 parts, Rhizoma Drynariae 6 parts, Fructus Psoraleae 8 parts, Radix Dipsaci 12 parts, Caulis Spatholobi 8 parts, Herba Epimedii 10 parts, Olibanum 6 parts, Myrrha 6 parts, Fructus Arctii 12 parts, Rhizoma Chuanxiong 12 parts, Radix Angelicae Sinensis 12 parts.
3. a kind of medicine being used for the treatment of osteoporosis according to claim 1, is characterized in that:
Preparation method is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 40-45min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.40 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
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| CN201510653920.8A CN105106580A (en) | 2015-10-12 | 2015-10-12 | Medicine for treating osteoporosis |
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| CN201510653920.8A CN105106580A (en) | 2015-10-12 | 2015-10-12 | Medicine for treating osteoporosis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106109695A (en) * | 2016-09-07 | 2016-11-16 | 四川金堂海纳生物医药技术研究所 | One can effectively treat osteoporotic pill medicine and preparation method thereof |
| CN112717047A (en) * | 2021-03-09 | 2021-04-30 | 西安医学院第二附属医院 | Medicine for treating osteoporosis and treatment method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101700302A (en) * | 2009-11-16 | 2010-05-05 | 张晨 | Oral traditional Chinese medicine composition for treating osteoporosis |
| CN103566152A (en) * | 2013-10-10 | 2014-02-12 | 陈友望 | Osteoporosis-prevention herbal tea formula |
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2015
- 2015-10-12 CN CN201510653920.8A patent/CN105106580A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101700302A (en) * | 2009-11-16 | 2010-05-05 | 张晨 | Oral traditional Chinese medicine composition for treating osteoporosis |
| CN103566152A (en) * | 2013-10-10 | 2014-02-12 | 陈友望 | Osteoporosis-prevention herbal tea formula |
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| 卢心宇: "辨证治疗老年性骨质疏松症", 《福建中医学院学报》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106109695A (en) * | 2016-09-07 | 2016-11-16 | 四川金堂海纳生物医药技术研究所 | One can effectively treat osteoporotic pill medicine and preparation method thereof |
| CN112717047A (en) * | 2021-03-09 | 2021-04-30 | 西安医学院第二附属医院 | Medicine for treating osteoporosis and treatment method thereof |
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