CN104996783A - Preparation method of immune-type Chinese herbal medicine fermented feed - Google Patents
Preparation method of immune-type Chinese herbal medicine fermented feed Download PDFInfo
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- CN104996783A CN104996783A CN201510365655.3A CN201510365655A CN104996783A CN 104996783 A CN104996783 A CN 104996783A CN 201510365655 A CN201510365655 A CN 201510365655A CN 104996783 A CN104996783 A CN 104996783A
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Abstract
The present invention belongs to the technical field of feed and microbial fermentation, and particularly relates to a preparation method of an immune-type Chinese herbal medicine fermented feed. Astragalus membranaceus powder, haw powder, eucommia ulmoides leaf powder, tomato pulp, glucose, yeast extract and water are mixed and blended into a thick seriflux, and the seriflux is heated, soaked, sterilized, and cooled, and inoculated with bacillus licheniformis, aspergillus niger and bacillus coagulans, fermented, and then mixed in proportion with corn flour, soybean meal, puffed soybean flour, whey powder, plasma protein powder, sucrose and premix, fermented, and dried to obtain the immune-type Chinese herbal medicine fermented feed. The feed is rich in active small peptides, astragalus membranaceus polysaccharides, eucommia ulmoides chlorogenic acid, tomatine, maslinic acid and lactic acid, and has the characteristics that the feed is high in nutrition, easy in digestion, good in palatability, low in anti-nutritional factor contents, and strong in immunity promoting effects, etc. At the same time, the feed can increase feed intake, significantly enhance feed digestibility, eliminate anti-nutritional factors in feed, and reduce diarrhea of sucking piglets.
Description
Technical field
The invention belongs to feed and technical field of microbial fermentation, be specifically related to a kind of preparation method of immunologic pattern Chinese herbal medicine fermented feed.
Background technology
Pig-breeding big country of China.Within 2011, China live pig delivers 6.46 hundred million for sale, sow livestock on hand 4,800 ten thousand, and pork output reaches 5,053 ten thousand tons, needs nearly 2.0 hundred million tons of pig feed actual year.With regard to domestic current pig-breeding present situation, it is one of the biggest problem that disease takes place frequently, and often causes huge economic loss." support overweight anti-, anti-overweighting is controlled " has become the common recognition of aquaculture, how is allocated by feed nutrition and improves immunity of livestock and receive much attention in recent years, become rapidly hot research problem.
Research shows: medium-height grass the effective elements of the medicine is polysaccharide, saponins, alkaloid, organic acid, volatile oil, and these active ingredients can induce the quantity of body immune factor, strengthen immunocyte and cytophagous function, thus reach the effect improving immunity, and low toxic and side effect, noresidue, to person poultry safety.But the plant cell wall of Chinese herbal medicine is made up of cellulose, pectin and lignin etc., be not easy by animal and bird intestines microorganism or digestive ferment digestion of degrading, active ingredient many being difficult in cell is caused to discharge, but the plant cell wall of Chinese herbal medicine is made up of cellulose, pectin and lignin etc., be not easy by animal and bird intestines microorganism or digestive ferment digestion of degrading, cause active ingredient many being difficult in cell to discharge, its practical application effect is unsatisfactory.When current Chinese herbal medicine uses as feed addictive, addition all more than 2%, even have up to 5% ~ 10%, and the effective component just accounting for a wherein very little part worked.In order to improve the effect of Chinese herbal medicine, people are that the organic solvent such as utilize boiling, alcohol extracting or ether to carry is to improve the utilization rate of Chinese herbal medicine always for a long time.But these conventional method ubiquity recovery rates are low, cost is high, uneasy congruent unfavorable factor.And the current processing of pine needle meal is only pulverize.
In recent years, fermentation technique and zymolysis technique start to be widely used in Chinese herbal medicine extraction industry.Select appropriate enzyme and fermented bacterium and technique, not only can more leniently decompose plant cell wall tissue, accelerate release active ingredient in cell, and the impurity removing and affect liquid preparation can be decomposed as starch, protein, pectin etc., promote the low liposoluble ingredient of some polarity to be converted into glucosides class soluble in water and be conducive to extraction.Therefore, utilizing fermentable or enzymolysis to transform the Chinese medicines such as pine needle meal to improve drug effect, is also a kind of well thinking.Application cellulase and some enzymes such as protease, pectase not only can destroy plant cell wall, are conducive to the extraction of active ingredient, and the material such as protein, pectin can be carried out enzymolysis, impel Chinese herbal medicine better to utilize.
The Radix Astragali: taste is sweet, gas tepor, nontoxic, special tonifying Qi, be the panacea of tonifying Qi, obviously can strengthen immunologic function, improve body hypoxia-bearing and stress ability, promote body metabolism.
Hawthorn: containing multivitamin, tartaric acid, citric acid, crataegolic acid, malic acid etc., also containing the mineral matter such as brass class, lactone, carbohydrate, protein, fat and calcium, phosphorus, iron.Flavonoids contained by hawthorn and the substance such as vitamin C, carrotene block and reduce the generation of free radical, can strengthen the immunity of body, have anti-aging, anticancer effect.Meanwhile, hawthorn can promote the digestion of fat food, promotes newborn piglet gastric juice and endogenous enzymes secretion, cures mainly newborn piglet eating accumulation.
Folium cortex eucommiae: mildly bitter flavor, is rich in bark of eucommia chlorogenic acid, obviously can strengthen immunologic function.Mouse gavaging folium cortex eucommiae water decoction-alcohol sedimentation liquid 10g (crude drug)/kg, be used in conjunction 10 days, can 2 be suppressed, delayed allergy caused by 4-dinitrofluorobenzene (DNCB), and the T cell percentage that can resist caused by heavy dose of hydrocortisone reduces, tumor-bearing mice peripheral blood T cells percentage can be made to increase, and peritoneal macrophage phagocytic function strengthens, to the regulating action of cellular immunity display two-phase.Folium cortex eucommiae water decoction 12g/kg gavages, and engulfs erythrocytic function and has a significant effect, phagocytic activity is increased to mouse macrophage under hydrocortisone effect, shows that the bark of eucommia has the effect of enhanced machine body immunity function.
Tomato: be rich in the multiple element such as tomatin, vitamin A, C, B1, B2 and carrotene and calcium, phosphorus, potassium, magnesium, iron, zinc, copper and iodine, also containing protein, carbohydrate, organic acid, cellulose.Lycopene is the wholefood composition that the oxidation resistance that finds at occurring in nature is at present the strongest, and its oxidation resistance is 32 times of bata-carotene, 100 times of vitamin E especially.Scientific research is verified, and it can scavenging free radicals, has anti-ageing, Tumor suppression, strengthens body immunity, reduces the multiple efficacies such as angiocardiopathy and pre-anti-cancer.Therefore, the various health products on market are always in very great demand, and its effect strengthening body immunity enjoys people to pay close attention to especially.The organic acid such as malic acid, citric acid contained by tomato, can impel gastric secretion, to digestion that is fatty and protein.Increase acid concentration, adjustment gastrointestinal function, helps the rehabilitation of gastrointestinal disease.
Summary of the invention
For the technical problem existed in prior art, the object of the present invention is to provide the features such as a kind of nutrition is high, easy to digest, good palatability, ANFs content are low, Promote immunity function is strong.Can feed intake be improved simultaneously, significantly improve feed digestibility, and ANFs in feed can be eliminated, reduce the feed of the features such as newborn grice diarrhoea, be i.e. the preparation method of immunologic pattern Chinese herbal medicine fermented feed.
The technical solution adopted in the present invention is:
A preparation method for immunologic pattern Chinese herbal medicine fermented feed, it is characterized in that, step is as follows:
1., with astragalus membranaceus powder, hawthorn powder, Eucommia Leaf Powder, strained tomatoes and glucose, yeast extract, water for raw material, be 100:(10 ~ 50 by astragalus membranaceus powder, hawthorn powder, Eucommia Leaf Powder, strained tomatoes with the weight ratio of glucose, yeast extract, water): (10 ~ 50): (50 ~ 100): (2 ~ 20): (2 ~ 20): (50 ~ 500) hybrid modulation becomes underflow liquid;
2. after, by underflow liquid being warming up to 95 ~ 105 DEG C of lasting sterilizing 2 ~ 4h, cooling;
3., when underflow liquid cools to 30 ~ 40 DEG C, access prebiotic strain liquid, fermentation 8 ~ 128h, obtained Chinese herbal medicine fermentation medium, described prebiotic strain liquid is mixed by bacillus licheniformis, aspergillus niger and condensation lactic acid bacillus;
4., in Chinese herbal medicine fermentation medium, cereal dregs of beans raw material is mixed into, fermentation 2 ~ 48h, obtained immunologic pattern Chinese herbal medicine fermented feed after drying, described cereal dregs of beans raw material is mixed by corn flour, bean cake powder, soy bean powder, whey powder, SDPP, sucrose and 4% premix.
Preferably, described step 1. in astragalus membranaceus powder, hawthorn powder, Eucommia Leaf Powder, strained tomatoes and glucose, yeast extract, water weight ratio be 100:(20 ~ 40): (20 ~ 40): (60 ~ 80): (8 ~ 16): (8 ~ 16): (200 ~ 300).
Further, described step 3. in underflow liquid, prebiotic strain liquid weight ratio be 100:(1 ~ 20), fermentation 48 ~ 96h.
Preferably, described step 3. in underflow liquid, prebiotic strain liquid weight ratio be 100:(3 ~ 8).
Further, the weight ratio of bacillus licheniformis in described prebiotic strain liquid, aspergillus niger and condensation lactic acid bacillus is 100:(0 ~ 100): (0 ~ 100).
Preferably, the weight ratio of bacillus licheniformis in described prebiotic strain liquid, aspergillus niger and condensation lactic acid bacillus is 100:(80 ~ 100): (40 ~ 80).
Further, described step 4. in cereal dregs of beans raw material, Chinese herbal medicine fermentation medium weight ratio be 100:(1 ~ 30).
Preferably, described step 4. in cereal dregs of beans raw material, Chinese herbal medicine fermentation medium weight ratio be 100:(10 ~ 20).
Further, the weight ratio of described step 4. corn flour in cereal dregs of beans raw material, bean cake powder, soy bean powder, whey powder, SDPP, sucrose and premix is 100:(10 ~ 40): (5 ~ 40): (0 ~ 20): (0 ~ 10): (0 ~ 10): (0 ~ 10).
Preferably, the weight ratio of described step 4. corn flour in cereal dregs of beans raw material, bean cake powder, soy bean powder, whey powder, SDPP, sucrose and premix is 100:(15 ~ 30): (5 ~ 15): (8 ~ 15): (2 ~ 5): (2 ~ 5): (2 ~ 5).
The feed for piglet prepared by preparation method of the present invention, is rich in active small peptide, astragalus polyose, bark of eucommia chlorogenic acid, tomatin, crataegolic acid and lactic acid, has the features such as nutrition is high, easy to digest, good palatability, ANFs content are low, Promote immunity function is strong.Can feed intake be improved simultaneously, significantly improve feed digestibility, and ANFs in feed can be eliminated, reduce newborn grice diarrhoea.
Detailed description of the invention
Below with reference to embodiment, the present invention is described in detail.
embodiment 1
By 50kg astragalus membranaceus powder, 20kg hawthorn powder, 20kg Eucommia Leaf Powder, after 50kg strained tomatoes (fresh wet basis) mixes, add 250kg water again, be modulated into underflow liquid, lower the temperature after being warming up to 95 DEG C of sterilizing 4h, 2.0kg bacillus licheniformis is added when temperature drops to 35 DEG C, 1.5kg aspergillus niger and 1.0kg condensation lactic acid bacillus, after fermentation 36h, be mixed into 600kg corn flour, 200kg swelling soya dreg powder, 100kg12% albumen whey powder, 30kg SDPP, 30kg sucrose and 40kg4% premix, ferment after 48h again, immunologic pattern Chinese herbal medicine fermented feed is made in drying.
Wherein, described premix is piglet vitamin premix.
embodiment 2
By 400kg astragalus membranaceus powder, 300kg hawthorn powder, 300kg Eucommia Leaf Powder, after 400kg strained tomatoes (fresh wet basis) mixes, add 4000kg water again, be modulated into underflow liquid, be warming up to 95 DEG C to soak and lower the temperature after sterilizing 4h, 25kg bacillus licheniformis is added when temperature drops to 35 DEG C, 20kg aspergillus niger and 10kg condensation lactic acid bacillus, after fermentation 36h, be mixed into 6500kg corn flour, 1500kg swelling soya dreg powder, 800kg12% albumen whey powder, 500kg SDPP, 300kg sucrose and 400kg4% premix, ferment after 48h again, immunologic pattern Chinese herbal medicine fermented feed is made in drying.
Wherein, described premix is piglet vitamin premix.
Above content is only citing made for the present invention and explanation; affiliated those skilled in the art make various amendment to described specific embodiment or supplement or adopt similar mode to substitute; only otherwise depart from the design of invention or surmount this scope as defined in the claims, protection scope of the present invention all should be belonged to.
Claims (10)
1. a preparation method for immunologic pattern Chinese herbal medicine fermented feed, is characterized in that, step is as follows:
1., with astragalus membranaceus powder, hawthorn powder, Eucommia Leaf Powder, strained tomatoes and glucose, yeast extract, water for making raw material, be 100:(10 ~ 50 by the weight ratio of astragalus membranaceus powder, hawthorn powder, Eucommia Leaf Powder, strained tomatoes and glucose, yeast extract, water): (10 ~ 50): (50 ~ 100): (2 ~ 20): (2 ~ 20): (50 ~ 500) mix and blend is modulated into underflow liquid;
2. after, by underflow liquid being warming up to 95 ~ 105 DEG C of lasting sterilizing 2 ~ 4h, cooling;
3., when underflow liquid cools to 30 ~ 40 DEG C, access prebiotic strain liquid, fermentation 8 ~ 128h, obtained Chinese herbal medicine fermentation medium, described prebiotic strain liquid is mixed by bacillus licheniformis, aspergillus niger and condensation lactic acid bacillus;
4., in Chinese herbal medicine fermentation medium, cereal dregs of beans raw material is mixed into, fermentation 2 ~ 48h, obtained immunologic pattern Chinese herbal medicine fermented feed after drying, described cereal dregs of beans raw material is mixed by corn flour, bean cake powder, soy bean powder, whey powder, SDPP, sucrose and 4% premix.
2. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 1, it is characterized in that, described step 1. in astragalus membranaceus powder, hawthorn powder, Eucommia Leaf Powder, strained tomatoes and glucose, yeast extract, water weight ratio be 100:(20 ~ 40): (20 ~ 40): (60 ~ 80): (8 ~ 16): (8 ~ 16): (200 ~ 300).
3. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 1, is characterized in that, described step 3. in underflow liquid, prebiotic strain liquid weight ratio be 100:(1 ~ 20), fermentation 48 ~ 96h.
4. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 3, is characterized in that, described step 3. in underflow liquid, prebiotic strain liquid weight ratio be 100:(3 ~ 8).
5. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 3 or 4, it is characterized in that, the weight ratio of bacillus licheniformis in described prebiotic strain liquid, aspergillus niger and condensation lactic acid bacillus is 100:(0 ~ 100): (0 ~ 100).
6. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 5, it is characterized in that, the weight ratio of bacillus licheniformis in described prebiotic strain liquid, aspergillus niger and condensation lactic acid bacillus is 100:(80 ~ 100): (40 ~ 80).
7. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 1, is characterized in that, described step 4. in cereal dregs of beans raw material, Chinese herbal medicine fermentation medium weight ratio be 100:(1 ~ 30).
8. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 7, is characterized in that, described step 4. in cereal dregs of beans raw material, Chinese herbal medicine fermentation medium weight ratio be 100:(10 ~ 20).
9. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 1, it is characterized in that, the weight ratio of described step 4. corn flour in cereal dregs of beans raw material, bean cake powder, soy bean powder, whey powder, SDPP, sucrose and 4% premix is 100:(10 ~ 40): (5 ~ 40): (0 ~ 20): (0 ~ 10): (0 ~ 10): (0 ~ 10).
10. the preparation method of a kind of immunologic pattern Chinese herbal medicine fermented feed according to claim 9, it is characterized in that, the weight ratio of described step 4. corn flour in cereal dregs of beans raw material, bean cake powder, soy bean powder, whey powder, SDPP, sucrose and 4% premix is 100:15 ~ 30:5 ~ 15:8 ~ 15:2 ~ 5:2 ~ 5:2 ~ 5.
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Cited By (7)
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| CN105341348A (en) * | 2015-12-03 | 2016-02-24 | 合肥五粮泰生物科技股份有限公司 | Preparation method of immune type Chinese herbal medicine fermented feed |
| CN105767518A (en) * | 2016-03-30 | 2016-07-20 | 南宁市百济生物工程有限公司 | Feed capable of improving animal meat quality and flavor as well as preparation method thereof |
| CN105941918A (en) * | 2016-05-26 | 2016-09-21 | 广东旺大集团股份有限公司 | Traditional herbal medicine fermenting type lactating sow feed and preparation method thereof |
| CN106074928A (en) * | 2016-07-04 | 2016-11-09 | 庞高统 | Sheep fermented feed Chinese medicine, sheep fermented feed and preparation method thereof |
| CN106071245A (en) * | 2016-07-04 | 2016-11-09 | 庞高统 | Pig fermented feed Chinese medicine, pig fermented feed and preparation method thereof |
| CN109430518A (en) * | 2018-10-25 | 2019-03-08 | 黑龙江惊哲森林农业科技开发有限责任公司 | A kind of novel straw biodynamic fermentation heap and preparation method thereof |
| CN109430519A (en) * | 2018-10-25 | 2019-03-08 | 黑龙江惊哲森林农业科技开发有限责任公司 | A kind of novel straw feed bio-fermented liquid and preparation method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105341348A (en) * | 2015-12-03 | 2016-02-24 | 合肥五粮泰生物科技股份有限公司 | Preparation method of immune type Chinese herbal medicine fermented feed |
| CN105767518A (en) * | 2016-03-30 | 2016-07-20 | 南宁市百济生物工程有限公司 | Feed capable of improving animal meat quality and flavor as well as preparation method thereof |
| CN105941918A (en) * | 2016-05-26 | 2016-09-21 | 广东旺大集团股份有限公司 | Traditional herbal medicine fermenting type lactating sow feed and preparation method thereof |
| CN106074928A (en) * | 2016-07-04 | 2016-11-09 | 庞高统 | Sheep fermented feed Chinese medicine, sheep fermented feed and preparation method thereof |
| CN106071245A (en) * | 2016-07-04 | 2016-11-09 | 庞高统 | Pig fermented feed Chinese medicine, pig fermented feed and preparation method thereof |
| CN109430518A (en) * | 2018-10-25 | 2019-03-08 | 黑龙江惊哲森林农业科技开发有限责任公司 | A kind of novel straw biodynamic fermentation heap and preparation method thereof |
| CN109430519A (en) * | 2018-10-25 | 2019-03-08 | 黑龙江惊哲森林农业科技开发有限责任公司 | A kind of novel straw feed bio-fermented liquid and preparation method thereof |
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Application publication date: 20151028 |