CN104983983A - Traditional Chinese medicine composition for treating gynecological disease and preparation thereof - Google Patents
Traditional Chinese medicine composition for treating gynecological disease and preparation thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating gynecological disease and a preparation thereof. The traditional Chinese medicine composition is technically characterized by combining a suppository and powder, wherein the suppository is prepared from rheum officinale, sanguisorba officinalis, daemonorops draco and borneol, and the powder is prepared from broom cypress fruits, common cnidium fruits, radix sophorae flavescentis and golden cypress. The traditional Chinese medicine composition and the preparation thereof have the effects of clearing away heat and toxic materials, cooling blood to relieve pain, promoting blood circulation to remove blood stasis, expelling decay to promote fresh blood production, dispelling the wind to eliminate dampness, and killing parasites to relieve itching. The traditional Chinese medicine composition is clinically used for treating cervical erosion, cervical cyst, bacterial vaginitis, colpitis mycotica, trichomonas vaginitis, mycoplasma and chlamydia vaginitis, advanced menorrhea caused by damp-heat type menorrhea, gonorrhoea uncleanness and face black spots caused by gynaecopathia, and has the remarkable effect.
Description
Technical field
The invention belongs to tcm field, relate to a kind of Chinese medicine composition and preparation thereof of inside and outside combined therapy gynaecopathia.
Background technology
Gynecological inflammation is the common disease of women, mainly refer to the inflammation (vulvitis, vaginitis, cervicitis, metritis, pelvic inflammatory disease, adnexitis, sexually transmitted disease (STD) etc.) of female sex organ, usually there is different acute and chronic inflammations in the genitals of women, in the inflammation being subject to occurring after the invasion and attack of various pathogenic bacterium are infected.Pathogen is mainly staphylococcus, streptococcus, escherichia coli and anaerobe, is secondly gonorrhea diplococcus, tubercule bacillus, has infusorian and rice bar in protozoon.In particular cases caused by chemical substance and lonizing radiation
Inflammation is treated not in time, except inflammation may be caused mutually to spread with except cross infection in each physiological site, can bring many complication, all can produce harmful effect to immunologic function, metabolism and hormonal system, even cause the malignant change at some position.If pregnant female, intrauterine infection, birth canal infection etc. can be caused to affect neonate, cause the serious consequences such as miscarriage, premature labor, congenital development deformity, mental retardation.The Drug therapy of present gynecological inflammation is mainly antibiotic medication, is easy to produce drug resistance.And normal flora in chemicals has been used of a specified duration destruction vagina uterine, form vicious cycle, inflammation easily recurs.Sterilization is cured the disease and has just been become sterilization to cause a disease, and the chemicals harm that normally sterilizing power is stronger is also larger.In addition, current use sharp optical, electrical such as to iron at traditional destructive therapy, not only effectively can not treat cervical disease, also cervix uteri can be damaged, cause cervical tissue fibrosis, make cervical surface " cicatrix is innumerable " and " uneven ", affect normal sexuality, in birth process, occur that cervix uteri is had difficult labour even afterwards.
Chinese medicine derives from natural product, after traditional Chinese medical science skill and technique is concocted, obtains better result of use, and have balance, the combination of homogeneous, natural, organic composition, natural owing to following the example of, toxic and side effects is smaller.Meanwhile, the traditional Chinese medical science has preparation administration history remote, and the policy of internal and external application is particular about in the treatment for disease, takes into account the exterior and the interior, reaches synchronous administration, the result synchronously taken effect.The invention provides a kind of Chinese medicinal composition preparation of internal and external application, according to gynopathic feature, use suppository and powder to carry out combination medicine-feeding treatment respectively, reach the object for the treatment of gynaecopathia.
Technology contents
The object of this invention is to provide a kind of Chinese medicine composition and preparation thereof for the treatment of gynaecopathia, it has effect of heat-clearing and toxic substances removing, cooling blood and relieving pain, blood circulation promoting and blood stasis dispelling, putrefaction removing and tissue regeneration promoting, expelling wind and removing dampness, killing parasites for relieving itching, and clinical cervical erosion, cervical cyst, bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, mycoplasma and chlamydia vaginitis, preceeded menorrhea caused by damp-heat type menstruation, the gonorrhea of being used for the treatment of is clean and because of the facial black speck etc. caused by gynaecopathia.Also can be used for women's day healthcare.
Chinese medicine composition and the preparation thereof of order treatment gynaecopathia of the present invention are made up of following two parts compositions and corresponding preparation thereof:
Compositions 1: Radix Et Rhizoma Rhei, Radix Sanguisorbae, Sanguis Draxonis, Borneolum Syntheticum.For the preparation of suppository.
Compositions 2: the Fructus Kochiae, Fructus Cnidii, Radix Sophorae Flavescentis, Cortex Phellodendri.For the preparation of powder.
Weight proportion and the corresponding preparation universal method thereof of the order treatment Chinese medicine composition of gynaecopathia of the present invention and the combination of Chinese medicine selected by preparation thereof are as follows:
Compositions 1: Radix Et Rhizoma Rhei 20-30 part, Radix Sanguisorbae 30-35 part, Sanguis Draxonis 18-25 part, Borneolum Syntheticum 2-3 part.For the preparation of suppository.
Suppository preparation method is as follows:
A the Radix Et Rhizoma Rhei of described weight proportion, Radix Sanguisorbae, Sanguis Draxonis are placed in frying pan by (), decoct with water 2 times, first time adds 8-10 times amount clear water, decocts 1-2 hour, cooling, filtering medicinal liquid, medicinal residues add 6-8 times amount clear water, decoct 1-2 hour, cooling, filter, merge twice medicinal liquid, concentrating under reduced pressure medicinal liquid to relative density is the clear paste of 1.2-1.35 (60-70 DEG C).
B (), by the lyophilizing of gained clear paste, adds Borneolum Syntheticum, pulverize, mix homogeneously.
C gained dried cream powder and appropriate suppository base mix by (), moulding, cooling, obtained suppository.
In suppository preparation method of the present invention, the preferred semi-synthetic fatty acid glyceride of suppository base or Polyethylene Glycol series.Suppository specification is general is 5 grams/, can carry out specification as required and zoom in or out during preparation, but each composition medicine constant rate.
Use in suppository of the present invention, has effect of heat-clearing and toxic substances removing, cooling blood and relieving pain, blood circulation promoting and blood stasis dispelling, putrefaction removing and tissue regeneration promoting.
Compositions 2: Fructus Kochiae 15-20 part, Fructus Cnidii 22-30 part, Radix Sophorae Flavescentis 8-16 part, Cortex Phellodendri 30-35 part.For the preparation of powder.
Powder preparation method is as follows: by the Chinese medicine composition co-grinding of described weight proportion, crosses 100 mesh sieves, packs after using ultraviolet disinfection.
Powder external of the present invention, has effect of heat-clearing and toxic substances removing, expelling wind and removing dampness, killing parasites for relieving itching.Coordinate suppository to use, avoid infection and spread and because of the scratching damage caused by pruritus, improve therapeutic effect.
Chinese medicine composition and the preparation for treating using method thereof of order treatment gynaecopathia of the present invention are as follows: inserted by suppository around cervix uteri, then powder is sprayed onto cervix uteri place and intravaginal, every 2-3 day is changed once.
The Chinese medicine composition of order treatment gynaecopathia of the present invention and more than 20 years of preparation clinical practice thereof, cure rate more than 95%, reliable for effect, heal the sick more than 10 ten thousand people.
Chinese medicine composition and the preparation tool thereof of order treatment gynaecopathia of the present invention have the following advantages: (a) therapeutic modality is advanced, and therapeutic administratp dosage form combination is reasonable, meets the compliance of clinical treatment, improves effect of targeted therapy.It is slow that conventional oral administration mode has absorption, and toxicity is large, the feature of weak curative effect, oral administration is subject to the impact of gastric acid PH, liver and intestinal enzyme, bioavailability is low, and reaching suitable blood drug level often needs heavy dose of administration, thus causes Drug resistance, toxicity and untoward reaction.The treatment of single topica often can't resolve the problem of Comprehensive Treatment, and cervical disease is not only Single-issue after all, and relates to the combinatorial problem of uterus, vagina, single therapy cervix uteri and do not treat vagina and must cause secondary and repeatedly infect and recur.The present invention adopts the therapeutic modality of inside and outside combination, can targeted therapy cervical disease, also can treat colpitis, and improve the comfort level in therapeutic process, reduce side reaction.B the Chinese medicine selected by Chinese medicine composition of () order of the present invention treatment gynaecopathia is all have good safety and the significant medical material of pharmacologically active.Suppository has effect of heat-clearing and toxic substances removing, cooling blood and relieving pain, blood circulation promoting and blood stasis dispelling, putrefaction removing and tissue regeneration promoting.Powder has effect of heat-clearing and toxic substances removing, expelling wind and removing dampness, killing parasites for relieving itching.
The category of gynaecopathia many in Gynecology of Chinese Medicine " leukorrheal diseases ".Its pathogeny is that impact is appointed, is with two arteries and veins, so that dai channel is failed to keep an appointment, and conception vessel is not disease admittedly because damp is for suffering from.The generation of damp or because of insufficiency of the spleen mistake fortune, water-damp not being transformed; Or lose solid because suffering from a deficiency of the kidney, envelope hides mistake department; Or because of health preserving careless, experience external damp.Treatment need with removing toxic substances, damp eliminating, heat clearing away, removing heat from blood, analgesic therapy, granulation promoting for sequence.The present composition selects the medical material with this type of effect, and defines more effective therapeutic combination on the basis considering compatible combination and dosage.
Selected by the present invention, medical material pharmacological effect is as follows:
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return spleen, stomach, large intestine, liver, pericardium channel.Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Be common to conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.Concoct: removing impurity, clean, run through, cut sheet or block, dry.
Radix Sanguisorbae: bitter in the mouth, acid, puckery, cold nature.Return liver, large intestine channel.Cooling blood for hemostasis, removing toxic substances sore.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.Concoct: removing impurity; Non-section person, cleans, removes residual stem, run through, cut sheet, dry.
Sanguis Draxonis: sweet in the mouth, salty, property is put down.GUIXIN, Liver Channel.Removing blood stasis and relieving pain, hemostasia and promoting granulation.Lose for falling to flutter, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury.Concoct: removing impurity, breaks into particle or pulverization.
Borneolum Syntheticum: acrid in the mouth, hardship, cold nature.GUIXIN, spleen, lung meridian.To have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
The Fructus Kochiae: acrid in the mouth, hardship, cold in nature.Return kidney, urinary bladder channel.Clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.
Fructus Cnidii: acrid in the mouth, hardship, warm in nature; Slightly poisonous.Return kidney channel.Warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus; Trichomonal vaginitis.
Radix Sophorae Flavescentis: bitter in the mouth, cold in nature.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.Concoct: removing retained root head, size separately, is cleaned, be dipped to about sixty percent thoroughly time, run through, cut sheet, dry.
Cortex Phellodendri: bitter in the mouth, cold in nature.Return kidney, urinary bladder channel.Heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.Concoct: removing impurity, spray clear water, runs through, shredding, dry.
The Chinese medicine composition of order treatment gynaecopathia of the present invention, selected Chinese crude drug is not that simple effect adds up, that there is sufficient pharmacology's compatibility basis and actual clinical medication experience, form the clinical proved recipe with definite effect, active compound has heat-clearing and toxic substances removing, cooling blood and relieving pain, blood circulation promoting and blood stasis dispelling, putrefaction removing and tissue regeneration promoting, expelling wind and removing dampness, killing parasites for relieving itching effect, the property of medicine sets off mutually, mutually merges.
Clinical efficacy
1. sample information
Sample case is the female patient of accepting for medical treatment for many years.Age reckling 17 years old, the oldest person 55 years old.Patient is the gynaecopathia suffered from various degree.Wherein part is recurrent intractable gynaecopathia patient.
2. Therapeutic Method
Select the present invention to treat the Chinese medicinal composition preparation of gynaecopathia, inserted by suppository around cervix uteri, then powder is sprayed onto cervix uteri place and intravaginal, every 2-3 day is changed once.It is for 3 times a course for the treatment of.
3. therapeutic outcome
Clinical practice two more than ten years, treatment patient more than 10 ten thousand example, generally through 3 ~ 5 course of therapy, effective percentage more than 95%.
4. model case
(1), Zhang, 23 years old.Patient was in 2012 5 next boy of monthly output, because postpartum recuperating is improper, cause puerperal cervix uteri inflammation infection inflammation, in July, 2013, cervix uteri occurred rotten to the corn, unbearably, the dense thick blackout of leucorrhea, goes examination in hospital to be diagnosed as cervical hypertrophy to pain pruritus, III degree is rotten to the corn, congested, papillary, and surperficial purulent secretion contact bleeding is obvious.Colposcopy, cervical scraping smear, antibacterial culturing, after seven days, cervical biopsy, pathological diagnosis is CIN-II level.After implement conization for rotten to the corn focus, preoperative routine examination chemical examination, operation next day of being admitted to hospital, leaves hospital for three days, ten Tianhougong Palace neck wound surface massive hemorrhage further consultations.There is obvious recurrent infection on inspection, owing to just finishing operation, should not perform an operation again, go home to rest, the state of an illness worsens very soon, owing to cannot trust original hospital and doctor, come here to seek medical advice, confirm on inspection, not yet occur that large area infects, can also pass through Drug therapy, so arrangement and use suppository of the present invention and powder combination preparation are treated, the same day, pruritus stopped, after the course for the treatment of, hemorrhage disappearance, disappearance of swelling and ache after two courses for the treatment of, leucorrhea starts normally.Remove examination in hospital after five courses for the treatment of, it is normal that display wound has started healing, and cervix uteri shape size is normal.This case confirms that the present composition and formulation compositions have good restitution in treating after surgery.
(2), Liu so-and-so, 32 years old.Patient suffered from urethritis from 2010, rear merging pudendum pruritus repeatedly, fail to cure always, recently day by day serious, daily life walking very inconvenience, after using antibiotic therapy, the state of an illness fails to be controlled, still feel pudendum its itch unbearable, lie awake all night, urine twinge, come here to seek medical advice, after diagnosing for urinary tract infection merges colpitis, after giving a course for the treatment of of treatment through using suppository of the present invention and powder combination preparation, situation is eased, pudendum is itched and is bitterly slightly subtracted, urine is not bitterly, after rear continuation uses suppository of the present invention and powder combination preparation to give a course for the treatment of of treatment, thoroughly rehabilitation, recover normal.
(3), Zhang, 36 years old.Patient married in 2005,6 years unpregnancies, adhered to that after having eaten various Western medicine and hormone, cause menolipsis 2 years, duration is felt dizzy, and mental status extreme difference, conjugal relation was once collapsed with western medical treatment always.Sought medical advice in here afterwards, and leucorrhea thickness is confirmed as in diagnosis, many more than 1 year of amount, often with the soreness of waist and lower abdomen pendant pain, has nearly 1 month exacerbation of symptoms.Patient's private prosecution love life is over the past two years contraception never, and husband checks no abnormality seen, but not conceived yet so far.Nearest sexual life has sexual anhedonia, has courageous and upright secretions time after sexual intercourse.I advises that she first removes examination in hospital, and check result confirms as cervix uteri hyperemia, the place's mucosal erosion of cervix uteri mouth, rotten to the corn face cerise, and coverage rate reaches 1/2, and the distribution of visible petechia, rotten to the corn tissue particles shape changes.For typical chronic cervicitis, moderate and severe cervical, infertility.In conjunction with on the basis of check result, I allocates Chinese medicine, treats with the suppository of invention and powder, after three treatment courses for the treatment of, recover menstrual period normal gradually, measure medium, color is scarlet, and leucorrhea amount is few, abnormal smells from the patient is normal, and check the rotten to the corn face of cervical mucosa after five courses for the treatment of and disappear, cervix uteri is as before smooth.In pregnancy in November, 2013.
(4) Wang, 28 years old.2010 years marry, prepare to want child, can half a year Wang belly also lose sound always.All the time, the leucorrhea of Wang is all abnormal, adularescent bean curd slag specimen sometimes, she does not also take notice of, thinks married women all like this, or relevant with menstrual cycle, just wash with water every night and wash, she also once suspected there is vaginitis herself, but she does not have the symptoms such as serious pruritus, dysurea, sexual anhedonia, so do not go examination in hospital to treat always yet.In order to want child, or to examination in hospital, checking and finding that uterus, adnexa, hormonal readiness are also normal, just having colpitis mycotica.Consider that Wang is in the standby pregnant stage, avoid medication, so thing preparation combined according to the invention as far as possible, adjustment principal agent proportioning, gentle administration, prepares suppository and powder uses, to suppress the growth of candidiasis, allow it loosen mood, feel at ease standby pregnant, after the course for the treatment of, check that mycete disappears, discontinue medication, using the sodium bicarbonate water washing vagina with 2% ~ 4% instead, every day 1 ~ 2 time, 2 weeks was 1 course for the treatment of.Dry pudendum to be wiped after flushing, keep xerosis vulae.Wang's pregnancy after 2 months, the whole pregnancy period is all very smooth, and gives birth to a healthy boy baby.
(5) Luo, 38 years old.Patient flows out red or white liquid from intravaginal from August, 2007, and as water from washing rice is watery, taste is extremely smelly, can not stop for a long time, visit Duo Jia hospital over 6 years all over, fail to cure, on July 20th, 2014 always, come here to seek medical advice, inquire on inspection, find that Luo notes health very much.Every day, except washing one's hands for several times, in order to ensure lower body part cleaning, also adhering to using every day acid gynaecologic cleaning disinfectant to clean pudendum, and using disinfection pad.I had never expected excessively to clean and destroy intravaginal sour environment on the contrary.Because intravaginal environment is faintly acid, have again many floras jointly to exist, the mutual restrictive function between flora can suppress certain Pseudomonas excessively increase and cause a disease, and this is the one nature system of defense of human body.Mutual restricting relation between the weakly acidic condition of vagina and Pseudomonas destroys by cleaning vagina undoubtedly, and the premunition of vagina epithelium is declined, and causes cervicitis.After confirming the patient's condition, I allows her stop using external-use lotion immediately, and use combination preparation suppository of the present invention and powder treatment instead, after adhering to 3 courses for the treatment of, intractable inflammation obtains medical treatment, and now thoroughly recovers, and leucorrhea amount is few, and abnormal smells from the patient is normal, and daily life recovers normal.
Specific embodiment
Embodiment one
(1) preparation of suppository
(a) composition prescription: Radix Et Rhizoma Rhei 200 grams, Radix Sanguisorbae 300 grams, Sanguis Draxonis 180 grams, Borneolum Syntheticum 20 grams.
(b) preparation method: the Radix Et Rhizoma Rhei of described weight proportion, Radix Sanguisorbae, Sanguis Draxonis are placed in frying pan, decoct with water 2 times, first time adds 600 grams of clear water, decocts 2 hours, cooling, filtering medicinal liquid, medicinal residues add 500 grams of clear water, decoct 1 hour, cooling, filter, merge twice medicinal liquid, concentrating under reduced pressure medicinal liquid to relative density is the clear paste of 1.2-1.35 (60-70 DEG C).By the lyophilizing of gained clear paste, add Borneolum Syntheticum, pulverize, mix homogeneously, weighs about 150 grams.By 100 grams of semi-synthetic fatty acid glyceride heat fused, add 150 grams of active component, fully mix well, moulding, cooling, obtained taper suppository.
(2) preparation of powder
(a) composition prescription: the Fructus Kochiae 150 grams, Fructus Cnidii 220 grams, Radix Sophorae Flavescentis 80 grams, Cortex Phellodendri 300 grams.
B () preparation method: by the Chinese medicine composition co-grinding of described weight proportion, crosses 100 mesh sieves, pack after using ultraviolet disinfection, gets powder delivery during use with health swab stick is sticky.
(3) usage: insert around cervix uteri by suppository during use, is then sprayed onto cervix uteri place and intravaginal by powder, and every 2-3 day is changed once.It is for 3 times a course for the treatment of.
Embodiment two
(1) preparation of suppository
(a) composition prescription: Radix Et Rhizoma Rhei 300 grams, Radix Sanguisorbae 350 grams, Sanguis Draxonis 250 grams, Borneolum Syntheticum 30 grams.
(b) preparation method: the Radix Et Rhizoma Rhei of described weight proportion, Radix Sanguisorbae, Sanguis Draxonis are placed in frying pan, decoct with water 2 times, first time adds 900 grams of clear water, decocts 2 hours, cooling, filtering medicinal liquid, medicinal residues add 700 grams of clear water, decoct 1 hour, cooling, filter, merge twice medicinal liquid, concentrating under reduced pressure medicinal liquid to relative density is the clear paste of 1.2-1.35 (60-70 DEG C).By the lyophilizing of gained clear paste, add Borneolum Syntheticum, pulverize, mix homogeneously, weighs about 180 grams.By 100 grams of Macrogol 4000 heat fused, add 180 grams of active component, fully mix well, moulding, cooling, obtained taper suppository.
(2) preparation of powder
(a) composition prescription: the Fructus Kochiae 200 grams, Fructus Cnidii 300 grams, Radix Sophorae Flavescentis 160 grams, Cortex Phellodendri 350 grams.
B () preparation method: by the Chinese medicine composition co-grinding of described weight proportion, crosses 100 mesh sieves, pack after using ultraviolet disinfection, gets powder delivery during use with health swab stick is sticky.
(3) usage: insert around cervix uteri by suppository during use, is then sprayed onto cervix uteri place and intravaginal by powder, and every 2-3 day is changed once.It is for 3 times a course for the treatment of.
Claims (4)
1. treat Chinese medicine composition and the preparation thereof of gynaecopathia, this Chinese medicine composition and corresponding dosage form as follows:
Compositions 1: Radix Et Rhizoma Rhei, Radix Sanguisorbae, Sanguis Draxonis, Borneolum Syntheticum.Dosage form is suppository.
Compositions 2: the Fructus Kochiae, Fructus Cnidii, Radix Sophorae Flavescentis, Cortex Phellodendri.Dosage form is powder.
2. treat Chinese medicine composition and the preparation thereof of gynaecopathia as claimed in claim 1, it is as follows that its each compositions commonly uses weight:
Compositions 1: Radix Et Rhizoma Rhei 20-30 part, Radix Sanguisorbae 30-35 part, Sanguis Draxonis 18-25 part, Borneolum Syntheticum 2-3 part.
Compositions 2: Fructus Kochiae 15-20 part, Fructus Cnidii 22-30 part, Radix Sophorae Flavescentis 8-16 part, Cortex Phellodendri 30-35 part.
3. as described in claim 1,2, treat Chinese medicine composition and the preparation thereof of gynaecopathia, its formulation preparation method is as follows:
(1) preparation of suppository: the Radix Et Rhizoma Rhei of described weight proportion, Radix Sanguisorbae, Sanguis Draxonis are placed in frying pan by (a), decoct with water 2 times, first time adds 8-10 times amount clear water, decocts 1-2 hour, cooling, filtering medicinal liquid, medicinal residues add 6-8 times amount clear water, decoct 1-2 hour, cooling, filter, merge twice medicinal liquid, concentrating under reduced pressure medicinal liquid to relative density is the clear paste of 1.2-1.35 (60-70 DEG C).B (), by the lyophilizing of gained clear paste, adds Borneolum Syntheticum, pulverize, mix homogeneously.C gained dried cream powder and appropriate suppository base mix by (), moulding, cooling, obtained suppository.
(2) preparation of powder: by the compositions co-grinding of described weight proportion, crosses 100 mesh sieves, packs after disinfection by ultraviolet light.
4. as described in claim 1,2,3, treat Chinese medicine composition and the preparation thereof of gynaecopathia, clean and because of the application in the facial black speck disease caused by gynaecopathia in treatment cervical erosion, cervical cyst, bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, mycoplasma and chlamydia vaginitis, the preceeded menorrhea caused by damp-heat type menstruation, gonorrhea.
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| CN110946895A (en) * | 2019-12-21 | 2020-04-03 | 郑远元 | Formula and preparation method of traditional Chinese medicine bacteriostatic foot bath liquid |
| CN113521146A (en) * | 2021-07-13 | 2021-10-22 | 西安浩然药业有限责任公司 | Formula and preparation method of liquid gynecological antibacterial agent |
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Application publication date: 20151021 |