CN104964858B - A kind of closed tissue dewatering system and its control method - Google Patents
A kind of closed tissue dewatering system and its control method Download PDFInfo
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- CN104964858B CN104964858B CN201510267306.8A CN201510267306A CN104964858B CN 104964858 B CN104964858 B CN 104964858B CN 201510267306 A CN201510267306 A CN 201510267306A CN 104964858 B CN104964858 B CN 104964858B
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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Abstract
The invention discloses a kind of closed tissue dewatering system and its control method,In the system,Treatment fluid gateway is connected by valve with paraffin container and reagent container,Closed tissue dewatering system also includes the first triple valve,Second triple valve,3rd triple valve and the 4th triple valve,The first port of 3rd triple valve and the first port of the 4th triple valve are connected with gas inlet-outlet,The second port of 4th triple valve is connected with air intake and gas outlet respectively,The second port of 3rd triple valve is connected with gas outlet,Entrance of the first port and public port of second triple valve respectively with air intake and air pump is connected,Outlet of the second port and public port of first triple valve respectively with gas outlet and air pump is connected,The first port of first triple valve,The second port of second triple valve,The public port of 3rd triple valve and the public port of the 4th triple valve are interconnected.The system dependable performance, dehydrating effect can be improved.
Description
【Technical field】
The present invention relates to a kind of closed tissue dewatering system and its control method.
【Background technology】
Tissue processor, which realizes, need to be fixed to censorship tissue specimen, be dehydrated, be transparent, waxdip processing, be to make stone
The crucial pre-treatment step of block sections.
Tissue processor is the working condition by controlling flow element with programmable electronic circuit, allows reagent
(formalin, alcohol, dimethylbenzene and paraffin etc.) can be consolidated to the tissue in tissue treatment cylinder in a certain order
The pathological analysis pre-treatments such as fixed, dehydration, transparent and waxdip, and can according to advance setting, control process process when
Between, temperature and pressure etc..Existing tissue processor is divided into two classes, and one kind is open type, and several are equipped with into different examinations
The reagent tank of agent circumferentially arranges or arranged in a straight line, then immerses in reagent tank tissue specimen successively with mechanical arm and is located
Reason；It is another kind of be by tissue treatment cylinder it is built-in attention pressure or negative pressure, the liquid in reagent bottle is pumped into or discharged successively
Fill and handled in the tissue treatment cylinder of tissue specimen.First kind dewaterer is gradually washed in a pan because capacity is small, security is low
Eliminate；Second class dewaterer capacity is big, and the system of complete machine is Seal Design, and degree of safety is high, and its design is widely recognized
Together.But because the second class dewaterer needs to meet following design：
(1) system needs long-term work in the operating mode of higher malleation and negative pressure；
(2) system needs to be heated and be incubated for a long time；
(3) reagent that system is flowed through includes formalin, alcohol, dimethylbenzene and other chemical reagent；
(4) liquid that system is flowed through also includes paraffin；
(5) system tissue block to be dealt with can be immersed in reagent, and reagent is also needed to from original passage after the completion of processing
Drain back into reagent bottle；
In view of the above feature of dewaterer, dewaterer can typically have following some reliabilities and safety issue：
(1) long-term positive/negative-pressure work makes system easily leak；
(2) aging and failure easily occur for long-term heating and insulation, the device part of system；
(3) corrosive reagent is flowed through for a long time, and system device part easily occurs aging corrosion and failed, while also easily leads
Reagent leakage is caused to damage environment and personnel；
(4) paraffin can solidify in low temperature, easily block flowed through passage；
(5) tissue handled by can deposit fat and fragment of tissue in reagent, and fluid component is easily blocked after accumulation
And pipeline；
(6) liquid that fluid system design system is soaked can not fully flow and organize fully contact, therefore be difficult
The concentration of reagent is maintained in processing procedure, tissue is fully dehydrated；
(7) dewaterer system can not accomplish to be fully sealed, and non-faulting leakage occurs in some cases in gas.
【The content of the invention】
For overcome the deficiencies in the prior art, the invention provides a kind of closed tissue dewatering system and control method,
So that dewatering system work is relatively reliable.
A kind of closed tissue dewatering system, including tissue treatment cylinder, paraffin container, reagent container and air pump, described group
Knitting processing cylinder includes being located at the tissue treatment cylinder lower end and the treatment fluid gateway of upper end and gas inlet-outlet, the place respectively
Reason liquid gateway is connected by valve with the paraffin container and reagent container, and the closed tissue dewatering system also includes first
Triple valve, the second triple valve, the 3rd triple valve and the 4th triple valve, the first port and the 4th triple valve of the 3rd triple valve
First port be connected with the gas inlet-outlet, the second port of the 4th triple valve respectively with air intake and gas outlet
Connection, the second port of the 3rd triple valve are connected with gas outlet, the first port and public port of second triple valve
The entrance with air intake and air pump is connected respectively, the second port and public port of first triple valve respectively with gas outlet and
Air pump outlet connection, the first port of first triple valve, the second port of the second triple valve, the 3rd triple valve it is public
The public port of port and the 4th triple valve is interconnected.
In one embodiment, in addition to condenser and first filter, the second port of first triple valve, the 3rd
The second port of triple valve connects the entrance of the condenser with the second port of the 4th triple valve, and the outlet of the condenser leads to
The first filter is crossed to be connected with gas outlet.
In one embodiment, the paraffin container includes paraffin gateway and paraffin tank atmosphere exports, the reagent
Container includes reagent gateway and reagent container gas vent, and the paraffin gateway and reagent gateway pass through valve and the place
The connection of liquid gateway is managed, the paraffin tank atmosphere outlet and reagent container gas vent are connected with the entrance of the condenser.
In one embodiment, the air intake includes the first air intake and the second air intake, the 4th triple valve
Second port is connected by the first check valve and the first air cleaner with the first air intake, the first end of second triple valve
Mouth is connected by the second air cleaner with the second air intake.
In one embodiment, in addition to liquid pump, the 5th triple valve, the first liquid valve, the second liquid valve, valve assembly and reagent
Valve, the tissue treatment cylinder also include the processing cylinder port positioned at the upper end of the tissue treatment cylinder, and the valve assembly includes
The public port of valve assembly first, the public port of valve assembly second and valve assembly reagent port, the treatment fluid gateway
It is connected by the first liquid valve with the public port of valve assembly first, the public port of the 5th triple valve passes through institute
State liquid pump and the second liquid valve and combine the connection of the public port of valve member second, the first port and second of the 5th triple valve with described
Entrance of the port respectively with the processing cylinder port and the condenser is connected, and the valve assembly reagent port passes through the examination
Agent valve is connected with the reagent container.
In one embodiment, in addition to liquid pump, the 5th triple valve, the 6th triple valve, the 7th triple valve, valve assembly and
Reagent valve, the valve assembly include valve assembly public port and valve assembly reagent port, the treatment fluid gateway point
First port not with the valve assembly public port and the 5th triple valve is connected, and the gas inlet-outlet is respectively with described
The first port of six triple valves connects with the first port of the 7th triple valve, the public port of the 6th triple valve and the second end
Mouthful it is connected respectively with the entrance of the liquid pump and the public port of the 5th triple valve, the public port of the 7th triple valve and the
Two-port netwerk is connected with the outlet of the liquid pump and the entrance of the condenser respectively, the second port of the 5th triple valve and institute
The entrance connection of condenser is stated, the valve assembly reagent port is connected by the reagent valve with the reagent container.
In one embodiment, negative pressure relief valve is provided between the second port of the 4th triple valve and air intake,
Malleation relief valve is provided between the second port of 4th triple valve and gas outlet.
In one embodiment, in addition to pressure sensor, the pressure sensor are used to detect the gas inlet-outlet
Air pressure, when the air pressure exceedes setting air pressure threshold value, the public port of the 4th triple valve is alternately and the described 4th 3
First port and the second port conducting of port valve.
Present invention also offers a kind of control method of described closed tissue dewatering system, it is characterized in that, including it is negative
Establishment step and malleation establishment step are pressed,
The negative pressure establishment step comprises the following steps：
The first port of the 4th triple valve is set to be connected with public port, the first port of the 3rd triple valve and public port connect
Lead to, the second port of the second triple valve connects with public port, the second port of the first triple valve connects with public port；
Start the air pump；
The malleation establishment step comprises the following steps：
The first port of the 4th triple valve is set to be connected with public port, the first port of the 3rd triple valve and public port connect
Lead to, the first port of the second triple valve connects with public port, the first port of the first triple valve connects with public port；
Start the air pump.
In one embodiment, also comprise the following steps：
When the air pressure of the gas inlet-outlet reach setting pressure after, make the 4th triple valve public port alternately with
First port and second port conducting.
Present invention also offers a kind of control method of described closed tissue dewatering system, it is characterized in that, described
In the case that air pump can not make the tissue treatment cylinder odd test agent, the control method comprises the following steps：
The public port of the 4th triple valve is set to be connected with first port, the public port of the 3rd triple valve and second port connect
The logical, public port of the 5th triple valve connects with first port, opens the reagent valve and the second liquid valve, closes first liquid
Valve；
Start the liquid pump.
Present invention also offers the control method of described closed tissue dewatering system, it is characterized in that, in addition to reagent
Circulation step：
Make public port and the first port conducting of the 5th triple valve, open the first liquid valve and the second liquid valve, close
The reagent valve；
Start the liquid pump, make the reagent in the tissue treatment cylinder public by the first liquid valve, valve assembly first successively
Port, the public port of valve assembly second, the second liquid valve, liquid pump, the public port and first port of the 5th triple valve altogether, from institute
Processing cylinder port is stated to be discharged into the tissue treatment cylinder.
Present invention also offers the control method of described closed tissue dewatering system, it is characterized in that, the described 4th 3
Be provided with negative pressure relief valve between the second port and air intake of port valve, the second port and gas outlet of the 4th triple valve it
Between be provided with malleation relief valve；
In the case where the air pump can not make the tissue treatment cylinder odd test agent, the control method includes following step
Suddenly：
The public port of the 3rd triple valve is set to be connected with first port, the public port and first end of the 6th triple valve
Mouth connects, the public port of the 4th triple valve connects with second port, the public port of the 5th triple valve connects with second port,
The public port of 7th triple valve connects with second port, the public port of the 4th triple valve connects with second port；
Open the reagent valve and liquid pump.
Present invention also offers the control method of described closed tissue dewatering system, it is characterized in that, the described 4th 3
Be provided with negative pressure relief valve between the second port and air intake of port valve, the second port and gas outlet of the 4th triple valve it
Between be provided with malleation relief valve；
In the case where the air pump can not make the tissue treatment cylinder row reagent, the control method includes following step
Suddenly：
The public port of the 3rd triple valve is set to be connected with first port, the public port and first end of the 7th triple valve
Mouth connects, the public port of the 5th triple valve connects with second port, the public port of the 6th triple valve connects with second port,
The public port of 4th triple valve connects with second port；
Open the reagent valve and liquid pump.
Present invention also offers the control method of described closed tissue dewatering system, it is characterized in that, the described 4th 3
Be provided with negative pressure relief valve between the second port and air intake of port valve, the second port and gas outlet of the 4th triple valve it
Between be provided with malleation relief valve；
The control method also includes reagent circulation step：
The public port of the 5th triple valve is set to be connected with first port, the public port of the 6th triple valve and second port connect
It is logical, the public port of the 7th triple valve connects with first port, the public port of the 3rd triple valve connects with second port, the 4th
The public port of triple valve connects with second port, closes the reagent valve；
Start the liquid pump, make the reagent in the tissue treatment cylinder successively by the 5th triple valve, the 6th triple valve, liquid
Pump, the 7th triple valve, it is discharged into from the gas inlet-outlet in the tissue treatment cylinder.
The beneficial effects of the invention are as follows：
By using four air pump, the first triple valve to the 4th triple valve triple valves so that take out, arrange the sheet of reagent (paraffin)
System architecture is relatively simple, and dependable performance.
By pressure sensor and relief valve, the stabilization of positive/negative-pressure when controlling drawing liquid, while the prison for passing through pressure sensor
Control is acted on, it is ensured that system over-pressed will not be revealed；
Standby power system (using the agent of liquid pump odd test or the associated components of row's reagent) is designed, (is utilized in main power system
The associated components of reagent (paraffin) are taken out, arranged to air pump) failure when, can by standby power system maintain machine normal work, carry
High system reliability；
By paraffin and reagent passage separate design, reduce the probability of blocking and blocking, pass through the insulation of reagent passage
System, allow reagent passage by heating routing restoration can be made unimpeded when blocking；
By designing removable filter device, the risk that fragment of tissue blocks is reduced；
The circulation reagent function that standby power system is realized is designed, improves the uniformity of reagent and being sufficiently mixed for dehydration,
Improve dehydrating effect.
【Brief description of the drawings】
Fig. 1 is the closed tissue dewatering system of the embodiment of the present invention 1；
Fig. 2 is the closed tissue dewatering system of the embodiment of the present invention 2；
Fig. 3 is the closed tissue dewatering system of the embodiment of the present invention 3；
Fig. 4 is the closed tissue dewatering system of the embodiment of the present invention 4；
Fig. 5 is the closed tissue dewatering system of the embodiment of the present invention 5.
【Embodiment】
The preferred embodiment to invention is described in further detail below.
Embodiment 1
As shown in figure 1, a kind of closed tissue dewatering system of embodiment, including tissue treatment cylinder, paraffin container, reagent
Container, air pump P, the first triple valve V1, the second triple valve V2, the 3rd triple valve V3, the 4th triple valve V4, the first check valve CV1,
Second check valve CV2, pressure sensor PS, the first air cleaner cnd1, the second air cleaner cnd2, negative pressure switch
NPS, normal pressure switch PPS, condenser, (activated carbon) filter, valve assembly, rotary valve, reagent valve (V5, V6, V7, V8V9,
V10、V11、V12、V13、V14、V15、V16)。
Tissue treatment cylinder includes positioned at the tissue treatment cylinder lower end and the treatment fluid gateway of upper end and gas going out respectively
Entrance, tissue treatment cylinder are furnished with liquid level sensor LS, sealing ring, heating plate, temperature sensor and filter FL.At tissue
It can be square, cylinder etc. to manage cylinder shape；The liquid level sensor is assemblied in casing wall different height, can detect different height
The liquid level of degree；The liquid level sensor can be resistance-type, condenser type, float-type or photo-electric；The sealing ring is assemblied in
On tissue treatment cylinder cylinder cap, the cavity of cylinder can be handled after close the cover with seal tissue；The sealing ring can be fluorubber,
PTFE or metal material；The heating plate is pasted in tissue treatment cylinder outer wall, and tissue treatment cylinder is heated；The temperature
Sensor can be fitted in tissue treatment cylinder outer wall, inwall, heating plate outer wall, inwall or by Screw assembly in tissue treatment
The inside of cylinder；The temperature sensor can be resistance-type, condenser type or infrared temperature detection；The filter FL can be torn open
Unload, filter membrane can make quick-replaceable type.
Paraffin container is furnished with paraffin case, heating plate and temperature sensor, and the heating plate is pasted in paraffin box outer wall, to wax
Case is heated；The temperature sensor can be fitted in the outer wall of paraffin container, inwall, heating plate outer wall, inwall etc.；It is described
Paraffin cylinder is placed in paraffin case, is designed with handle and cylinder cap, can conveniently be extracted and be prevented paraffin from splashing；The paraffin cylinder
Material can be the good material of the heat conductivilitys such as stainless steel, aluminium alloy.
The public port for the treatment of fluid gateway and rotary valve connects, each branch port of rotary valve respectively with each paraffin
The paraffin gateway connection of container, the paraffin gas outlet of paraffin container are connected with the entrance of condenser.Treatment fluid gateway
It is connected with the public port VCP of valve assembly, each branch port (valve assembly reagent port) of valve assembly passes through respectively
Corresponding reagent valve is connected with the reagent gateway of each reagent container, for example, a branch port VOP passes through the 5th reagent valve
V5 is connected with one of fixating reagent (such as 30% formalin etc.) container, the reagent gateway of reagent container and condenser
Entrance connection.Dehydrated reagent can use ethanol, such as the ethanol of 80%, 85%, 90% and 100% concentration, and transparent agent can
To use 100% hexichol first, cleaning reagent can use clear water, 100% ethanol or 100% hexichol first.
The first port NC (normally closed port) and the 4th triple valve V4 first port NC of the 3rd triple valve V3 is (normally closed
Port) it is connected with the gas inlet-outlet, second port NO (normally opened port) one side of the 4th triple valve V4 is successively
It is connected by the first check valve CV1 and the first air cleaner cnd1 with the first air intake, it is single on the other hand passes sequentially through second
Being connected to the entrance of valve CV2 and condenser, the outlet of condenser is connected by (activated carbon) filter with gas outlet, and the described 3rd
Triple valve V3 second port NO (normally opened port) is connected with the entrance of condenser, the first port NC of the second triple valve V2
(normally closed port) is connected by the second air cleaner cnd2 with the second air intake, the first triple valve V1 first port NC,
Two triple valve V2 second port NO (normally opened port), the 3rd triple valve V3 public port C and the 4th triple valve V4's is public
Port C is interconnected (such as can be interconnected using four-way connection), the second triple valve V2 public port C's and air pump P
The outlet of entrance A connections, the public port C of the first triple valve V1 and air pump connects, second port NO (normally opened port) with
The entrance connection of condenser.
To detect the air pressure at the gas inlet-outlet of tissue treatment cylinder, pressure sensor PS can be set pressure sensor PS
Put in B points.
Negative-pressure detection device NPS is used for the air pressure for detecting air pump P entrances A, if air pump P entrances A negative pressure exceedes negative pressure
Threshold value, then system control air pump P stop operating.Malleation detection means PPS is used for the air pressure for detecting air pump P outlets, if air pump P
The malleation of entrance exceedes malleation threshold value, then system control air pump P stops operating.
The flow of the odd test agent of the present embodiment 1 is as follows (by taking fixating reagent corresponding to reagent valve V5 as an example)：Tissue treatment cylinder
Cylinder cap close and lock, reagent valve V5 be powered open (remaining reagent valve is not turned on, rotary valve also without connection paraffin hold
Device), the 3rd triple valve V3 and the 4th triple valve V4 energizations make respective public port C and normally closed port NC turn on (first respectively
Triple valve V1 and the second triple valve V2 are not powered, and normally opened port NO connects with public port C), and booster air pump P, at tissue
Gas in reason cylinder passes through the 3rd triple valve V3's and the 4th triple valve V4 respectively under the swabbing action of pump from gas inlet-outlet
NC mouths flow out into after the second triple valve V2 NO mouths from the second triple valve V2 C mouths, and flow through inside air pump P, then from the
One triple valve V1 NO mouths outflow, row is into ambient atmosphere after the condensation of condenser and filter filtering.In this process,
Tissue treatment cylinder interior gradually forms negative pressure, the pressure in pressure monitor sensor tissue treatment cylinder, the pressure needed for reach
Afterwards, power on/off the 4th triple valve V4, which is repeated, to be made the 4th triple valve V4 C-terminal (alternating) turns on NO mouths or NC mouths in turn,
When C mouths and NO mouths turn on, extraneous gas flows into air-channel system by the first air cleaner cnd1 and check valve CV1, in
The unnecessary negative pressure established with air pump, can stablize pressure within the specific limits, liquid is sucked into group under a steady pressure
Knit in processing cylinder and immersion treatment is carried out to the tissue that the inside is placed.
Row's Reagent protocol of the present embodiment 1 is as follows (by taking fixating reagent corresponding to reagent valve V5 as an example)：Tissue treatment cylinder
Cylinder cap is closed and locked, and reagent valve V5 is powered, and (remaining reagent valve is not turned on opening, and rotary valve also holds without connection paraffin
Device), the first triple valve V1, the second triple valve V2, the 3rd triple valve V3, the 4th triple valve V4 energizations make respective common port C mouths
Turned on normal-closed end NC mouths, booster air pump P, extraneous gas is entered the second triple valve V2 NC by the second air cleaner cnd2
After mouthful, flow through inside air pump P, then pass through the 3rd triple valve V3 and the 4th triple valve V4 NC from the first triple valve V1 NC mouths
Mouth enters the inside of tissue treatment cylinder, and in this process, tissue treatment cylinder interior gradually forms malleation, pressure monitor sensor tissue
The pressure in cylinder is handled, after required pressure is reached, power on/off, which is repeated, to the 4th triple valve V4 makes the 4th triple valve V4
C-terminal turned in turn with NO mouths or NC mouths, when C mouths and NO mouths turn on, unnecessary malleation is flowed out by check valve CV2, is passed through
Row vents the unnecessary malleation of air pump P foundation into ambient atmosphere after condenser condensation and filter filtering, can be steady by pressure
Determine within the specific limits, the reagent that liquid is discharged into corresponding to reagent valve V5 out of tissue treatment cylinder under a steady pressure holds
In device, the gas flowed into reagent container flows into condenser by reagent container gas vent, by common conduit, by condensation
Row is into ambient atmosphere after device condensation and filter filtering.
The flow for taking out paraffin (by taking paraffin container corresponding to paraffin 1 as an example) of the present embodiment 1 is as follows：The cylinder of tissue treatment cylinder
Cover and lock, rotation valve passage rotates to the position (reagent valve V5 to V16 is turned off) of paraffin 1, is rotated corresponding to paraffin 1
Valve inlet and rotation valve outlet UNICOM.Then, it is identical with the flow of the odd test agent of the present embodiment 1, make negative in tissue treatment cylinder
Pressure reaches stable pressure, and paraffin is sucked into the tissue placed in tissue treatment cylinder to the inside and soaked under a steady pressure
Bubble processing.
The flow of row's paraffin (by taking paraffin container corresponding to paraffin 1 as an example) of the present embodiment 1 is as follows：The cylinder of tissue treatment cylinder
Cover and lock, rotation valve passage rotates to the position (reagent valve V5 to V16 is turned off) of paraffin 1, is rotated corresponding to paraffin 1
Valve inlet and rotation valve outlet UNICOM.Then, it is identical with the flow of row's reagent of the present embodiment 1, make in tissue treatment cylinder just
Pressure reaches stable pressure, and paraffin is discharged into out of tissue treatment cylinder in the wax cylinder corresponding to paraffin 1 under a steady pressure,
Flow into wax cylinder gas by paraffin tank atmosphere export, by common conduit flow into condenser, by condenser condensation and
Row is into ambient atmosphere after filter filtering.
The malleation Establishing process of the present embodiment 1 is as follows：The cylinder cap of tissue treatment cylinder closes and locked, then, with this implementation
The flow for establishing malleation of row's reagent of example 1 is identical, tissue treatment cylinder interior is gradually formed malleation, pressure sensor PS monitoring
Pressure in tissue treatment cylinder, after required pressure is reached, air pump P is stopped, the first triple valve V1, the second triple valve
V2, the 3rd triple valve V3, the 4th triple valve V4 power-off, respective NC mouths disconnect with C mouths, and the pressure in tissue treatment cylinder is by the 3rd
Triple valve V3 and the 4th triple valve V4 closings keep barotropic state.
The negative pressure Establishing process of the present embodiment 1 is as follows：Tissue treatment cylinder cylinder cap closes and locked, then, with the present embodiment 1
Odd test agent the flow for establishing negative pressure it is identical, tissue treatment cylinder interior is gradually formed negative pressure, pressure sensor PS monitoring groups
The pressure in processing cylinder is knitted, after required pressure is reached, air pump P is stopped, and the 3rd triple valve V3, the 4th triple valve V4 break
Electricity, NC mouths and the C mouths of valve disconnect, and the pressure in tissue treatment cylinder keeps negative by the 3rd triple valve V3 and the 4th triple valve V4 closings
Pressure condition.
The pressure release flow of the present embodiment 1 is as follows：In the case that tissue treatment cylinder inner sealing has malleation, the 4th triple valve V4 leads to
Electric C mouths and NC mouths conducting, the 3rd triple valve V3, which is closed, makes C mouths be turned on NO mouths, and the gas in cylinder passes through the 4th triple valve V4's
NC mouths, the 3rd triple valve V3 NO mouths enter condenser, and row arrives ambient atmosphere after condenser condensation and filter filtering
In, after the malleation in cylinder is excreted and atmospheric pressure keeps balancing；In the case that tissue treatment cylinder inner sealing has negative pressure, the four or three
Port valve V4, which is powered, turns on C mouths and NC mouths, and the 3rd triple valve V3, which is closed, makes C mouths be turned on NO mouths, and extraneous gas is by filter
The 3rd triple valve V3 NO mouths are flowed through with condenser, the 4th triple valve V4 NC mouths enter in tissue treatment cylinder, the negative pressure in cylinder
After being neutralized and atmospheric pressure keeps balancing.
The malleation monitoring alarm flow of the present embodiment 1 is as follows：Occur to block in fluid system and cause air pump P work discharges
In the case that gas can not be drained, air pump P exit can quickly form very high malleation, be arranged on air pump exit just
Pressure switch PPS feeds back to one signal of system after detecting the abnormal pressure, and system lets out the work for stopping air pump P and startup
Press flow.
The negative pressure monitoring alarm flow of the embodiment 1 is as follows：Occur to enter when blocking causes air pump P to work in fluid system
In the case that mouth can not suck gas, very high negative pressure can be quickly formed at air pump P entrance A, is arranged on air pump P porch
Negative pressure switch NPS is detected one signal of system is fed back to after the abnormal pressure, system is by the work for stopping air pump P and opens
Dynamic pressure release flow.
Embodiment 2
As shown in Fig. 2 the difference of the closed tissue dewatering system and the system of embodiment 1 of the present embodiment is：Utilize
Rotary valve selection connection tissue treatment cylinder and each reagent container or paraffin container, rotary valve have a public port, and
Multiple branch ports, each branch port connect a reagent container or paraffin container, and some branch is gated when rotary valve rotates
Behind port, corresponding container connects with tissue treatment cylinder.
The difference of the flow of the odd test agent of the present embodiment 2 and the flow of the odd test agent of embodiment 1 is：Embodiment 1 passes through
Valve assembly gates reagent container and tissue treatment cylinder, and reagent valve control reagent container corresponding to utilizing and valve assembly are led
It is logical, and the present embodiment 2 gates tissue treatment cylinder and corresponding reagent container by rotary valve, then, use is same as Example 1
Method make liquid be sucked under a steady pressure in tissue treatment cylinder to carry out immersion treatment to the tissue that the inside is placed.
Equally, row's Reagent protocol of the present embodiment 2, take out paraffin flow, row's paraffin flow, malleation Establishing process, negative pressure and build
Vertical flow, pressure release flow and malleation monitoring alarm flow are substantially the same manner as Example 1, will not be repeated here.
Embodiment 3
As shown in figure 3, closed tissue dewatering system of the closed tissue dewatering system of the present embodiment 3 in embodiment 1
A negative pressure relief valve DV1 and malleation relief valve DV2 are further increased, negative pressure relief valve DV1 is arranged on check valve CV1 and
Between the NO ends of four triple valves, malleation relief valve DV2 is arranged between the NO ends of check valve CV2 and the 4th triple valve.
Make during odd test agent or paraffin tissue treatment cylinder establish negative pressure process it is as follows：
3rd triple valve V3, which is powered, makes public port C and normally closed port NC turn on (the first triple valve V1, the second triple valve V2
It is not powered with the 4th triple valve V4, respective normally opened port NO connects with public port C), and booster air pump P, tissue treatment
Gas in cylinder enters the second triple valve V2 under the swabbing action of pump from gas inlet-outlet by the 3rd triple valve V3 NC mouths
NO mouths after, flowed out from the second triple valve V2 C mouths, and flow through inside air pump P, then from the first triple valve V1 NO mouth streams
Go out, row is into ambient atmosphere after the condensation of condenser and filter filtering.It is gradual in this process, tissue treatment cylinder interior
Negative pressure is formed, after the pressure formed in tissue treatment cylinder pressure set in advance more than negative pressure relief valve DV1, negative pressure relief valve
DV1 and check valve CV1 are automatically opened up, and extraneous gas passes through the first air cleaner cnd1, check valve CV1 and negative pressure relief valve
DV1 flows into air-channel system, neutralizes the unnecessary negative pressure that air pump is established, and pressure is stablized negative pressure relief valve DV1's within the specific limits
Setting value.
Row reagent or paraffin during make tissue treatment cylinder establish malleation process it is as follows：
First triple valve V1, the second triple valve V2 and the 3rd triple valve V3 are powered and make respective common port C mouths and normal-closed end
NC mouths are turned on, and the 4th triple valve V4 is remained turned-off, and C mouths is connected with NO mouths, booster air pump P, extraneous gas is by the second air
After filter c nd2 enters the second triple valve V2 NC mouths, flow through inside air pump P, then pass through from the first triple valve V1 NC mouths
3rd triple valve V3 NC mouths enter the inside of tissue treatment cylinder, and in this process, tissue treatment cylinder interior gradually forms malleation, when
After the pressure formed in tissue treatment cylinder exceedes malleation relief valve DV2 pressure set in advance, malleation relief valve DV2 and check valve
CV2 is automatically opened up, and unnecessary malleation is flowed out by malleation relief valve DV2 and check valve CV2, by condensing container condensation and mistake
Row vents the unnecessary malleation of air pump P foundation, pressure is stablized within the specific limits lets out in malleation into ambient atmosphere after filter filtering
Pressure valve DV2 setting value.
Embodiment 4
As shown in figure 4, closed tissue dewatering system of the closed tissue dewatering system of the present embodiment 4 in embodiment 3
Further increase：5th triple valve V17, the first liquid valve V18, the second liquid valve V19, liquid pump P1, valve assembly have two phases
Intercommunicated public port：The public port of valve assembly first, the public port of valve assembly second, tissue treatment cylinder also have position
Processing cylinder port in the upper end of tissue treatment cylinder.The treatment fluid gateway passes through the first liquid valve V18 and the valve group
The public port of component first connects, and the public port C of the 5th triple valve V17 passes through the liquid pump P1 and the second liquid valve V19
The connection of the public port of valve member second, first port NC and second port the NO difference of the 5th triple valve V17 are combined with described
It is connected with the entrance of the processing cylinder port and the condenser.
When tissue treatment cylinder can not be made to establish negative pressure and odd test agent by air pump P, following manner can be utilized to realize and taken out
Reagent (by taking reagent container corresponding to reagent valve V5 as an example)：
Tissue treatment cylinder cylinder cap closes and locked, the 4th triple valve V4, the 5th triple valve V17 be powered make respective C mouths and
NC mouths are turned on, and reagent valve V5, the second liquid valve V19, which are powered, to be opened, and is closed the first liquid valve V18, reagent valve V6 to V16, is started liquid pump
P1, the reagent corresponding to reagent valve V5 in reagent container are extracted out, by group under liquid pump P1 swabbing action out of reagent container
Close valve member second public port and flow into the second liquid valve V19, liquid flows through liquid pump P1, the 5th triple valve V17 from the second liquid valve V19
Behind NC ends, it is discharged into from the processing cylinder port at the top of tissue treatment cylinder in tissue treatment cylinder, liquid pump P1 continuous firings are liquid continuous
Tissue treatment cylinder is pumped into out of reagent container, at the same time, the gas inlet-outlet of unnecessary gas from tissue treatment cylinder is led in cylinder
The NO mouths for crossing the 4th triple valve V4 NC mouths into the 3rd triple valve V3 flow into condensing container, by condensing container condensation and mistake
Row is into ambient atmosphere after filter filtering.
This implementation can also realize reagent circulation, and flow is as follows：It is hydraulically full in tissue treatment cylinder to carry out tissue immersion
In the case of, tissue treatment cylinder cylinder cap closes and locked, and closes rotary valve and reagent valve V5 to V16, the 5th triple valve V17 are powered
Turn on C mouths and NC mouths, the first liquid valve V18, the second liquid valve V19, which are powered, to be opened, and liquid pump P1 starts, and liquid is from tissue treatment cylinder bottom
Portion flows into the second liquid valve V19 after the public passage that the first liquid valve V18 enters valve assembly, and liquid flows from the second liquid valve V19
Through liquid pump P1, the 5th triple valve V17 NC ends after, be discharged into tissue treatment cylinder from the processing cylinder port at the top of tissue treatment cylinder
Interior, liquid pump P1 continuous firings, the liquid in tissue treatment cylinder will continue to flow out from the bottom of tissue treatment cylinder, and top flows into, real
The circulation stirring of existing reagent, makes reagent uniform concentration distribution during tissue is handled, improves the effect of tissue treatment.
Embodiment 5
As shown in figure 5, closed tissue dewatering system of the closed tissue dewatering system of the present embodiment 5 in embodiment 3
Further increase：Liquid pump P1, the 5th triple valve V17, the 6th triple valve V18 and the 7th triple valve V19, the treatment fluid come in and go out
First port NC of the mouth respectively with the valve assembly public port and the 5th triple valve V17 is connected, the gas inlet-outlet point
First port NC not with the first port NC and the 7th triple valve V19 of the 6th triple valve V18 is connected, the 6th threeway
Valve V18 public port C and second port NO respectively with the entrance of the liquid pump P1 and the 5th triple valve V17 public port C
Connection, public port C and second port the NO outlet with the liquid pump P1 and the condensation respectively of the 7th triple valve V19
The entrance connection of device, the second port NO of the 5th triple valve V17 are connected with the entrance of the condenser.
In the case where air pump P can not realize odd test agent, odd test agent can be carried out in the following way (with V5 pairs of reagent valve
Exemplified by the reagent answered)：Tissue treatment cylinder cylinder cap closes and locked, and reagent valve V5, which is powered, opens (reagent valve V6 to V16 holdings pass
Close), the 3rd triple valve V3, the 6th triple valve V18 are powered makes the respective conducting of C mouths and NC mouths (the 4th triple valve V4, the 5th respectively
Triple valve V17 and the 7th triple valve V19 are remained turned-off, and respective C mouths is connected with NO mouths respectively), liquid pump P1 starts, at tissue
The gas in cylinder is managed under liquid pump P1 swabbing action by being flowed through after the 6th triple valve V18 NC mouths inside liquid pump P1, then
Flow out, arranged after condenser condensation and filter filtering into ambient atmosphere, herein mistake from the 7th triple valve V19 NO mouths
Journey, tissue treatment cylinder interior gradually form negative pressure, when the pressure formed in tissue treatment cylinder is set in advance more than negative pressure relief valve DV1
After fixed pressure, negative pressure relief valve DV1 and check valve CV1 are automatically opened up, extraneous gas by the first air cleaner cnd1,
Check valve CV1 and negative pressure relief valve DV1 flows into air-channel system, neutralizes the unnecessary negative pressure that air pump is established, pressure is within the specific limits
The stable setting value in negative pressure relief valve DV1, liquid are sucked into tissue treatment cylinder and the inside are placed under a steady pressure
Tissue carry out immersion treatment.
Row's Reagent protocol of the present embodiment 5 can be as follows：Tissue treatment cylinder cylinder cap closes and locked, and reagent valve V5 is powered and beaten
Open, the 3rd triple valve V3, the 7th triple valve V19, which are powered, turns on C mouths and NC mouths, the 5th triple valve V17 and the 6th triple valve V18
Closing makes respective C mouths be connected with NO mouths, starts liquid pump P1, and extraneous gas passes through the 5th triple valve by filter and condenser
After V17 NO and C mouths, then after NO and C mouths by the 6th triple valve V18, then pass through inside liquid pump P1, then from the seven or three
Port valve V19 NC mouths enter the inside of tissue treatment cylinder, and in this process, tissue treatment cylinder interior gradually forms malleation, works as tissue
After the pressure formed in processing cylinder exceedes malleation relief valve DV2 pressure set in advance, malleation relief valve DV2 and check valve CV2
Automatically open up, unnecessary malleation is flowed out by malleation relief valve DV2 and check valve CV2, by condenser condensation and filter
Row vents the unnecessary malleation of air pump foundation into ambient atmosphere after filtering, and pressure is stablized in malleation relief valve within the specific limits
DV2 setting value, liquid are discharged into the reagent container corresponding to reagent valve V5 out of tissue treatment cylinder under a steady pressure
Interior, the gas flowed into reagent container flows into condenser by common conduit, after condenser condensation and filter filtering
It is discharged in ambient atmosphere.
The flow of the reagent circulation of the present embodiment 5 is as follows：The hydraulically full situation for carrying out tissue immersion in tissue treatment cylinder
Under, tissue treatment cylinder cylinder cap closes and locked, and the 5th triple valve V17, the 7th triple valve V19, which are powered, makes respective C mouths and NC mouths
Conducting, the 3rd triple valve V3 and the 4th triple valve V4 are closed, and respective C mouths is connected with NO mouths, reagent valve V5 to V16, rotation
Valve is closed, and liquid pump P1 starts, and liquid passes through the 5th triple valve V17 NC and C mouths from tissue treatment cylinder bottom portion, then by the six or three
Port valve V18 NO and C mouths, flow through by the 7th triple valve V19 C mouths and NC mouths after liquid pump P1, from the top of tissue treatment cylinder
It is discharged into tissue treatment cylinder, liquid pump P1 continuous firings, the liquid in tissue treatment cylinder will continue to flow from the bottom of tissue treatment cylinder
Go out, top flows into, and realizes the circulation stirring of reagent, makes reagent uniform concentration distribution during tissue is handled, and improves at tissue
The effect of reason.
Above content is to combine specific preferred embodiment further description made for the present invention, it is impossible to is assert
The specific implementation of the present invention is confined to these explanations.For general technical staff of the technical field of the invention,
On the premise of not departing from present inventive concept, some simple deduction or replace can also be made, should all be considered as belonging to the present invention by
The scope of patent protection that the claims submitted determine.
Claims (13)
1. a kind of closed tissue dewatering system, including tissue treatment cylinder, paraffin container, reagent container and air pump, the tissue
Processing cylinder includes being located at the tissue treatment cylinder lower end and the treatment fluid gateway of upper end and gas inlet-outlet, the processing respectively
Liquid gateway is connected by valve with the paraffin container and reagent container, it is characterized in that：The closed tissue dewatering system is also
Including the first triple valve, the second triple valve, the 3rd triple valve and the 4th triple valve, the first port of the 3rd triple valve and
The first port of four triple valves is connected with the gas inlet-outlet, the second port of the 4th triple valve respectively with air intake
Connected with gas outlet, the second port of the 3rd triple valve is connected with gas outlet, the first port of second triple valve and
Entrance of the public port respectively with air intake and air pump is connected, the second port and public port of first triple valve respectively with
Gas outlet connects with the outlet of air pump, the first port of first triple valve, the second port of the second triple valve, the 3rd threeway
The public port of the public port of valve and the 4th triple valve is interconnected；
Also include condenser and first filter, the second port of first triple valve, the second port of the 3rd triple valve and
The second port of 4th triple valve connects the entrance of the condenser, the outlet of the condenser by the first filter with
Gas outlet connects；
Also include liquid pump, the 5th triple valve, the first liquid valve, the second liquid valve, valve assembly and reagent valve, the tissue treatment cylinder is also
Including the processing cylinder port positioned at the upper end of the tissue treatment cylinder, the valve assembly includes the common port of valve assembly first
Mouthful, the public port of valve assembly second and valve assembly reagent port, the treatment fluid gateway by the first liquid valve with
The public port of valve assembly first connection, the public port of the 5th triple valve by the liquid pump and the second liquid valve with
The combination valve member second public port connection, the first port and second port of the 5th triple valve respectively with the processing
Cylinder port connects with the entrance of the condenser, and the valve assembly reagent port passes through the reagent valve and the reagent container
Connection.
2. closed tissue dewatering system as claimed in claim 1, it is characterized in that, the paraffin container includes paraffin gateway
Exported with paraffin tank atmosphere, the reagent container includes reagent gateway and reagent container gas vent, and the paraffin comes in and goes out
Mouth and reagent gateway are connected by valve with the treatment fluid gateway, the paraffin tank atmosphere outlet and reagent container gas
Outlet is connected with the entrance of the condenser.
3. closed tissue dewatering system as claimed in claim 1, it is characterized in that, the air intake include the first air intake and
Second air intake, the second port of the 4th triple valve pass through the first check valve and the first air cleaner and the first air intake
Connection, the first port of second triple valve are connected by the second air cleaner with the second air intake.
4. closed tissue dewatering system as claimed in claim 1, it is characterized in that, the second port of the 4th triple valve with
Negative pressure relief valve is provided between air intake, malleation pressure release is provided between the second port of the 4th triple valve and gas outlet
Valve.
5. closed tissue dewatering system as claimed in claim 1, it is characterized in that, in addition to pressure sensor, the pressure
Sensor is used for the air pressure for detecting the gas inlet-outlet, when the air pressure exceedes setting air pressure threshold value, the 4th threeway
The public port of valve alternately turns on the first port and second port of the 4th triple valve.
6. a kind of control method of closed tissue dewatering system as claimed in claim 1, it is characterized in that, including negative pressure foundation
Step and malleation establishment step,
The negative pressure establishment step comprises the following steps：
The first port of the 4th triple valve is connected with public port, the first port of the 3rd triple valve connects with public port,
The second port of second triple valve connects with public port, the second port of the first triple valve connects with public port；
Start the air pump；
The malleation establishment step comprises the following steps：
The first port of the 4th triple valve is connected with public port, the first port of the 3rd triple valve connects with public port,
The first port of second triple valve connects with public port, the first port of the first triple valve connects with public port；
Start the air pump.
7. the control method of closed tissue dewatering system as claimed in claim 6, it is characterized in that, also comprise the following steps：
After the air pressure of the gas inlet-outlet reaches setting pressure, make the public port alternating and first of the 4th triple valve
Port and second port conducting.
8. a kind of control method of closed tissue dewatering system as claimed in claim 1, it is characterized in that, the air pump without
In the case that method makes the tissue treatment cylinder odd test agent, the control method comprises the following steps：
The public port of the 4th triple valve is connected with first port, the public port of the 3rd triple valve connects with second port,
The public port of 5th triple valve connects with first port, opens the reagent valve and the second liquid valve, closes the first liquid valve；
Start the liquid pump.
9. a kind of control method of closed tissue dewatering system as claimed in claim 1, it is characterized in that, in addition to reagent follows
Ring step：
The public port and first port for making the 5th triple valve turn on, unlatching the first liquid valve and the second liquid valve, described in closing
Reagent valve；
Start the liquid pump, make the reagent in the tissue treatment cylinder successively by the first liquid valve, the common port of valve assembly first
Mouth, the public port of valve assembly second, the second liquid valve, liquid pump, the public port and first port of the 5th triple valve, from described
Reason cylinder port is discharged into the tissue treatment cylinder.
10. a kind of closed tissue dewatering system, including tissue treatment cylinder, paraffin container, reagent container and air pump, the tissue
Processing cylinder includes being located at the tissue treatment cylinder lower end and the treatment fluid gateway of upper end and gas inlet-outlet, the processing respectively
Liquid gateway is connected by valve with the paraffin container and reagent container, it is characterized in that：The closed tissue dewatering system is also
Including the first triple valve, the second triple valve, the 3rd triple valve and the 4th triple valve, the first port of the 3rd triple valve and
The first port of four triple valves is connected with the gas inlet-outlet, the second port of the 4th triple valve respectively with air intake
Connected with gas outlet, the second port of the 3rd triple valve is connected with gas outlet, the first port of second triple valve and
Entrance of the public port respectively with air intake and air pump is connected, the second port and public port of first triple valve respectively with
Gas outlet connects with the outlet of air pump, the first port of first triple valve, the second port of the second triple valve, the 3rd threeway
The public port of the public port of valve and the 4th triple valve is interconnected；
Also include condenser and first filter, the second port of first triple valve, the second port of the 3rd triple valve and
The second port of 4th triple valve connects the entrance of the condenser, the outlet of the condenser by the first filter with
Gas outlet connects；
Also include liquid pump, the 5th triple valve, the 6th triple valve, the 7th triple valve, valve assembly and reagent valve, the valve assembly
Including valve assembly public port and valve assembly reagent port, the treatment fluid gateway is public with the valve assembly respectively
Port connects with the first port of the 5th triple valve, the gas inlet-outlet respectively with the first port of the 6th triple valve and
The first port connection of 7th triple valve, the public port and second port of the 6th triple valve enter with the liquid pump respectively
Mouthful connected with the public port of the 5th triple valve, the public port and second port of the 7th triple valve respectively with the liquid pump
Outlet connected with the entrance of the condenser, the second port of the 5th triple valve is connected with the entrance of the condenser,
The valve assembly reagent port is connected by the reagent valve with the reagent container.
11. a kind of control method of closed tissue dewatering system as claimed in claim 10, it is characterized in that, the described 4th 3
Be provided with negative pressure relief valve between the second port and air intake of port valve, the second port and gas outlet of the 4th triple valve it
Between be provided with malleation relief valve；
In the case where the air pump can not make the tissue treatment cylinder odd test agent, the control method comprises the following steps：
The public port of the 3rd triple valve is set to be connected with first port, the public port of the 6th triple valve and first port connect
It is logical, the public port of the 4th triple valve connects with second port, the public port of the 5th triple valve connects with second port, the 7th
The public port of triple valve connects with second port, the public port of the 4th triple valve connects with second port；
Open the reagent valve and liquid pump.
12. a kind of control method of closed tissue dewatering system as claimed in claim 10, it is characterized in that, the described 4th 3
Be provided with negative pressure relief valve between the second port and air intake of port valve, the second port and gas outlet of the 4th triple valve it
Between be provided with malleation relief valve；
In the case where the air pump can not make the tissue treatment cylinder row reagent, the control method comprises the following steps：
The public port of the 3rd triple valve is set to be connected with first port, the public port of the 7th triple valve and first port connect
It is logical, the public port of the 5th triple valve connects with second port, the public port of the 6th triple valve connects with second port, the 4th
The public port of triple valve connects with second port；
Open the reagent valve and liquid pump.
13. a kind of control method of closed tissue dewatering system as claimed in claim 10, it is characterized in that, the described 4th 3
Be provided with negative pressure relief valve between the second port and air intake of port valve, the second port and gas outlet of the 4th triple valve it
Between be provided with malleation relief valve；
The control method also includes reagent circulation step：
The public port of the 5th triple valve is connected with first port, the public port of the 6th triple valve connects with second port,
The public port of 7th triple valve connects with first port, the public port of the 3rd triple valve connects with second port, the four or three
The public port of port valve connects with second port, closes the reagent valve；
Start the liquid pump, make reagent in the tissue treatment cylinder successively by the 5th triple valve, the 6th triple valve, liquid pump,
7th triple valve, it is discharged into from the gas inlet-outlet in the tissue treatment cylinder.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510267306.8A CN104964858B (en) | 2015-05-22 | 2015-05-22 | A kind of closed tissue dewatering system and its control method |
| PCT/CN2015/084230 WO2016187937A1 (en) | 2015-05-22 | 2015-07-16 | Closed type tissue dehydration system and control method therefor |
| HK15111957.1A HK1211086A1 (en) | 2015-05-22 | 2015-12-03 | A closed typed tissue dehydration system and controlling method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510267306.8A CN104964858B (en) | 2015-05-22 | 2015-05-22 | A kind of closed tissue dewatering system and its control method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104964858A CN104964858A (en) | 2015-10-07 |
| CN104964858B true CN104964858B (en) | 2018-03-30 |
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ID=54218908
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510267306.8A Active CN104964858B (en) | 2015-05-22 | 2015-05-22 | A kind of closed tissue dewatering system and its control method |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN104964858B (en) |
| HK (1) | HK1211086A1 (en) |
| WO (1) | WO2016187937A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106872245A (en) * | 2017-04-07 | 2017-06-20 | 金华市益迪医疗设备有限公司 | A kind of biological tissue dehydrator for being provided with emission-control equipment |
| CN107024372A (en) * | 2017-04-18 | 2017-08-08 | 金华市益迪医疗设备有限公司 | The biological tissue dehydrator of automatic detection can be carried out to conveying decoction system leak |
| CN110108533B (en) * | 2019-05-24 | 2023-10-24 | 常州派斯杰医疗设备有限公司 | Tissue dehydrator |
| JP2023544241A (en) * | 2020-08-10 | 2023-10-23 | ライカ ビオズュステムス ヌスロッホ ゲーエムベーハー | Xylene-free tissue processing device and method for processing tissue |
| CN112834297B (en) * | 2020-12-09 | 2022-11-04 | 山东骏腾医疗科技有限公司 | Liquid path system of rapid pathological multi-cylinder tissue dehydrator |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1605243B1 (en) * | 2004-06-07 | 2008-12-03 | Milestone S.r.l. | Method and apparatus for microwave assisted tissue processing |
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2015
- 2015-05-22 CN CN201510267306.8A patent/CN104964858B/en active Active
- 2015-07-16 WO PCT/CN2015/084230 patent/WO2016187937A1/en active Application Filing
- 2015-12-03 HK HK15111957.1A patent/HK1211086A1/en unknown
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3892197A (en) * | 1974-04-22 | 1975-07-01 | Thomas D Kinney | Light microscopy processing apparatus |
| US7850913B2 (en) * | 2006-01-06 | 2010-12-14 | Sakura Seiki Co., Ltd. | Method of paraffin-penetration treatment for tissue preparation and apparatus for the treatment |
| CN201803880U (en) * | 2010-03-11 | 2011-04-20 | 湖北泰维科技实业有限公司 | Fully-automatic and totally-closed tissue dehydrator |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2016187937A1 (en) | 2016-12-01 |
| HK1211086A1 (en) | 2016-05-13 |
| CN104964858A (en) | 2015-10-07 |
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