CN104507553A - Testing and drying device for testing the function of dialysers - Google Patents

Testing and drying device for testing the function of dialysers Download PDF

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Publication number
CN104507553A
CN104507553A CN201480002012.6A CN201480002012A CN104507553A CN 104507553 A CN104507553 A CN 104507553A CN 201480002012 A CN201480002012 A CN 201480002012A CN 104507553 A CN104507553 A CN 104507553A
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CN
China
Prior art keywords
interface
air
dislysate
adapter cover
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201480002012.6A
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Chinese (zh)
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CN104507553B (en
Inventor
汤姆·鲍尔
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Alpha Plans Limited-Liability Co
Alpha Plan GmbH
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Alpha Plans Limited-Liability Co
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Publication of CN104507553A publication Critical patent/CN104507553A/en
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Publication of CN104507553B publication Critical patent/CN104507553B/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24Dialysis ; Membrane extraction
    • B01D61/30Accessories; Auxiliary operation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D65/00Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/10Testing of membranes or membrane apparatus; Detecting or repairing leaks
    • B01D65/102Detection of leaks in membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D65/00Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/10Testing of membranes or membrane apparatus; Detecting or repairing leaks
    • B01D65/104Detection of leaks in membrane apparatus or modules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D67/00Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081After-treatment of organic or inorganic membranes
    • B01D67/0095Drying
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B9/00Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2313/00Details relating to membrane modules or apparatus
    • B01D2313/13Specific connectors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2313/00Details relating to membrane modules or apparatus
    • B01D2313/21Specific headers, end caps
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D63/00Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02Hollow fibre modules

Abstract

The invention relates to testing and drying devices for testing the function of dialysers, having a device which produces an air flow, at least one media source and at least one conveying device. These are notable particularly both for simple testing and for reliable and simple drying of the dialysers after testing thereof. For this purpose, these have a first adapter cap and a second adapter cap, each with a connector for a sealing connection to the dialyser, the diameter of the connectors of the adapter caps being greater than the diameters of the connectors of blood caps. The connector of the first adapter cap is a connector for an air inlet, a media inlet and a media outlet, in each case via a valve. The connector of the second adapter cap is a connector for an air outlet, a media inlet and a media outlet, in each case via a valve. Each of the dialysate connectors is a dialysate connector for an air inlet or an air outlet via at least one valve. In addition, actuation devices for the valves are coupled to a control device.

Description

For carrying out detection and the drying device of Function detection to dialyzer
Technical field
The present invention relates to a kind of detection and drying device for carrying out Function detection to dialyzer, its device with the flowing of generation air, at least one medium source and at least one conveying device.
Background technology
Be well known that, the manufacture process of Hollow fiber dialyzer starts to be introduced in dialyzer housing by fibre bundle.In fibrous encapsulation process subsequently, fiber end is closed, filled by pouring agent to avoid doughnut.In a subsequent step, cast cover is installed.In order to the block making the outer end of pouring agent arrival dialyzer housing, washing-round (umsp ü len) fiber end also forms homogeneous there, dialyzer housing rotates around its central point.After the hardening, peel off cast cover, and utilize multiple cutting process to pour into a mould means shortens, until the doughnut exposed can be seen.After pair cross-section carries out visual examination, in both sides, blood cover (Blutkappen) is installed.In testing process subsequently, check in fibre bundle whether there is defective fiber.For this reason, fill dialyzer with water, and carry out pressure detecting.Be placed in follow-up dry run by the dialyzer detected.Usually, dry run is the microwave drying with heated air drying subsequently.
Equipment for desciccator diaphragm module is known by document DE 298 02 402 U1.At this, by this equipment realize by microwave to liquid carry out non-conducting heating and by flowing dry gas derive moisture.
Known a kind of for the method and apparatus by microwave energy desciccator diaphragm module by document DE 103 33 639 B3, particularly dialyzer, it is with at least two fluidic interface, wherein, at least one film module puts into micro-wave oven by feeding device, fluidic interface is connected on scavenge system by coupling arrangement, then while percolation is carried out in the scavenging by scavenge system, on certain duration, make it be placed in microwave energy, then make itself and scavenge system again be separated and it be taken out from micro-wave oven.Meanwhile, by the known a kind of equipment for implementing the method for the document.
Utilize these solutions, during implemented dry run, do not get rid of film module be heated excessively, this may cause film module to damage.
After follow-up pressure detecting and visual examination, dialyzer is encapsulated.
Summary of the invention
Task of the present invention described is in claim 1: can detect simply and dry dialyzer.
This task is solved by the feature described in claim 1.
For carrying out the detection of Function detection and drying device to dialyzer with producing the device of air flowing, at least one medium source and at least one conveying device, this detection and drying device feature be especially not only the simple detection of dialyzer but also be after it is detected reliably and simply dry.
For this reason, this detection and drying device have the first adapter cover and the second adapter cover, and they are respectively with the interface for being tightly connected with dialyzer, and wherein, the interface diameter of adapter cover is greater than the interface diameter of blood cover.The interface of this first adapter cover is the interface exported for carrying out air input, medium input and medium respectively by valve.The interface of this second adapter cover is the interface exported for carrying out air output, medium input and medium respectively by valve.Wherein each dislysate interface is for carrying out air input by least one valve or carried out the dislysate interface of air output by least one valve in air input.In addition, the manipulation device of valve is connected on control device.
Carry out Function detection in order to the mode detected with wet density and carry out air oxygen detrition, advantageously, using adapter cover to replace blood cover.
The usual already installed blood of dialyzer covers in adaptive scope the free diameter such as with about 4mm.But the effective diameter of all doughnuts is obviously on it.By using the adapter cover with the free diameter of such as about 10mm, more cold air and/or hot-air can be made to flow through dialyzer.Therefore, relative to the effective diameter of the air interface of blood side, coefficient can be 3.0 to 3.5.
At this advantageously, being increased in when not increasing pressure at expulsion when air exports of volume flow is carried out.
Another advantage is, dislysate interface is isolated with follow-up air dried known heating using microwave relatively.But therefore the steam be present in dialysis fluid chamber be difficult to volatilization.Drying time is relatively long.And apparatus according to the invention be characterized in that, by dislysate interface, dialysis fluid chamber equally can by air, particularly hot-air percolation.Hence improve drying effect.
For known conventional wet Density Detection, cyclically apply cool-drying air in blood side, and to be inputted by medium in dialysis fluid side and forever apply transmembrane pressure (Transmembrandruck).And also can realize by device according to the present invention, carry out continuous percolation in blood side and dialysis fluid side with dry air just enough.But, device according to the present invention can certainly be utilized will to be inputted transmembrane pressure and the air stream of dialysis fluid side, the air stream cyclic switching of blood side of applying by medium.This can realize simply by the manipulation device connected with control device of control device and valve.At this, manipulation device is in known manner for opening and closing the input and output of corresponding air or medium.
Therefore, in order to optimizing process, change known dialyzer as follows and be manufactured on technical order, that is, after cutting and visual examination subsequently, carry out the Function detection by water and back to back air oxygen detrition at once.Until dry run completes just install blood cover.
As control device, can use with the known data handling system of such as known microcontroller form.
Therefore, during manufacture, after cutting and visual examination, testing process is performed.Then in same equipment, drying is carried out to the dialyzer by test at once.For this drying, only use hot-air.Blood cover is installed in ensuing process steps.After follow-up pressure detecting and visual examination, dialyzer is encapsulated.
The favourable design of the present invention provides in claim 2-11.
Improvement project according to claim 2, wherein each dislysate interface is the dislysate interface exported for carrying out air input, air output, medium input and medium respectively by valve.
Thus, to detect and drying device has the first adapter cover and the second adapter cover, they are respectively with the interface for being tightly connected with dialyzer, and wherein, the interface diameter of adapter cover is greater than the interface diameter of blood cover.The interface of the first adapter cover is the interface exported for carrying out air input, medium input and medium respectively by valve.The interface of the second adapter cover is the interface exported for carrying out air output, medium input and medium respectively by valve.Wherein each dislysate interface is the dislysate interface exported for carrying out air input, air output, medium input and medium respectively by valve.In addition, the manipulation device of valve is connected on control device.
Improvement project according to claim 3, this device has the support for fixing dialyzer in the mode that can get loose.In addition, at least one adapter cover is connected on the driver of orthoscopic effect, to make adapter cover be connected with fixing dialyzer hermetically, or can get loose from this dialyzer.Thus, detection and drying are automatically carried out.Further, can connect on the apparatus for laying dialyzer to be detected and/or detecting and the hand-control device of the dialyzer of drying for taking out.Advantageously, hand-control device is connected with control device.Thus, can fully automatically carry out detecting and drying.
Improvement project according to claim 4, control device for detecting dialyzer 1 is connected to the manipulation device of valve as follows, namely, wherein at least one interface of adapter cover and/or at least one dislysate interface are the interfaces for air input or medium input, at least one other interface of adapter cover and/or at least one dislysate interface are for the interface that air exports or medium exports, and close other valves.
Improvement project according to claim 5, control device for dry dialyzer is connected to the manipulation device of valve as follows, namely, the interface of the first adapter cover is the interface for air input, the interface of the second adapter cover is the interface exported for air, at least one dislysate interface is the dislysate interface for air input, and at least one dislysate interface is the dislysate interface exported for air, and closes other valves.
Improvement project according to claim 6, advantageously, the device producing air flowing is the device producing hot-air.
Further, improvement project according to claim 7, advantageously, the device producing hot-air is the compressor with follow-up air heat.This compressor can be known pump, air blast or screw compressor.
Improvement project according to claim 8, medium source is media Containers.
Improvement project according to claim 9, medium is water.
Improvement project according to claim 10, in order to monitor aridity, temperature sensor and/or humidity sensor are connected to the circuit exported for air, thus can know the temperature and/or humidity that flow out air.Aridity can be monitored simply thus.
Improvement project according to claim 11, the temperature sensor of circuit exported for air and/or humidity sensor are connected with control device.Thus, automatic detection and the drying of dialyzer is obtained.
Accompanying drawing explanation
Schematically illustrate embodiments of the invention in the accompanying drawings, and further illustrate hereinafter.Wherein:
Fig. 1 illustrates detection and drying device for carrying out Function detection to dialyzer; And
Fig. 2 illustrate with adapter cover dialyzer and band valvular interface.
Detailed description of the invention
Detection and drying device for carrying out Function detection to dialyzer mainly comprise: produce the device 2 of air flowing, medium source 3, conveying device 4, support for dialyzer, adapter cover 5, driver 6, valve 7 and control device with adapter cover 5.
Fig. 1 shows a kind of detection and drying device for carrying out Function detection to dialyzer 1 with schematic diagram.
In the simplest embodiment, medium source 3 is the containers 3 with medium.In FIG, control device valve 7 not being shown and being attached thereto.Valve 7 can be seen by the diagram of Fig. 2.
Fig. 2 shows with the dialyzer 1 of adapter cover 5 and the interface with valve 7 with schematic diagram.
Top is applicable to every other seven valves thereunder illustrated 7 for the Reference numeral 7 of the valve 7 at dialyzer interface 8 place.
In detection and drying device, dialyzer 1 is connected with the first adapter cover 5a and the second adapter cover 5b, and they are respectively with the interface for being tightly connected with dialyzer 1, and wherein, the interface diameter of adapter cover 5 is greater than the interface diameter of blood cover.
The interface of the first adapter cover 5a is for carrying out the interface that air input 9, medium input 10 and medium export 11 respectively by valve 7.
The interface of the second adapter cover 5b is for carrying out the interface that air output 12, medium input 10 and medium export 11 respectively by valve 7.
Wherein each dislysate interface is for carrying out air input by least one valve 7 or carried out the dislysate interface of air output by least one valve 7 in air input 12.
Wherein each dislysate interface 8 also can be for carrying out the dislysate interface 8 that air input 9, air output 12, medium input 10 and medium export 11 respectively by valve 7.
The manipulation device of valve 7 is connected on unshowned control device.
This device has support, and it is for fixing dialyzer 1 in the mode that can get loose.This support can be stationary positioned second adapter cover 5b simultaneously.First adapter cover 5a is connected on the driver 6 of orthoscopic effect, thus the first adapter cover is moved vertically.
Thus, the first adapter cover 5a can be connected with fixing dialyzer 1 hermetically, or can again get loose from this dialyzer.Driver 6 ensure that being tightly connected between dialyzer 1 and adapter cover 5 at the same time.
In order to detect dialyzer 1, control device is connected on the manipulation device of valve 7 as follows, that is,
Wherein at least one interface of-adapter cover 5 and/or at least one dislysate interface 8 are the interfaces for air input 9 or medium input 10,
At least one other interface of-adapter cover 5 and/or at least one dislysate interface 8 are the interfaces exporting 12 or medium output 11 for air, and wherein, other each valves 7 are closed.
In order to dry dialyzer 1, control device is connected on the manipulation device of valve 7 as follows, that is,
The interface of the-the first adapter cover 5a is the interface for air input 9,
The interface of the-the second adapter cover 5b is the interface for air output 12,
-at least one dislysate interface 8 is the dislysate interfaces 8 for air input 9,
-at least one dislysate interface 8 is the dislysate interfaces 8 for air output 12,
Wherein, other each valves 7 are closed.
The device 2 producing air flowing is the devices 2 producing hot-air, such as, be have the screw compressor 2 being carried out follow-up air heat by known electric heater.
Conveying device 4 is known suction pump for medium and/or compression pump 4.
In order to monitor aridity, temperature sensor and/or humidity sensor can be connected to the circuit for air output 12, thus can know temperature and/or the humidity of the air of outflow.The temperature sensor and/or the humidity sensor that export the circuit of 12 for air are connected with this control device.

Claims (11)

1. one kind for carrying out detection and the drying device of Function detection to dialyzer (1), device (2), at least one medium source (3) and at least one conveying device (4) that described detection and drying device flow with generation air, it is characterized in that
-described detection and drying device have the first adapter cover (5a) and the second adapter cover (5b), described first adapter cover and described second adapter cover are respectively with the interface for being tightly connected with described dialyzer (1), wherein, the interface diameter of described adapter cover (5) is greater than the interface diameter of blood cover
The interface of-described first adapter cover (5a) is the interface exporting (11) for carrying out air input (9), medium input (10) and medium respectively by valve (7),
The interface of-described second adapter cover (5b) is the interface exporting (11) for carrying out air output (12), medium input (10) and medium respectively by valve (7),
Each dislysate interface in-dislysate interface (8) is for carrying out air input (9) by least one valve (7) or carried out the dislysate interface (8) of air output (12) by least one valve (7) in air input (12)
The manipulation device of-described valve (7) is connected on control device.
2. detection according to claim 1 and drying device, it is characterized in that, each dislysate interface in described dislysate interface (8) is for the dislysate interface (8) carrying out air input (9) respectively by valve (7), air exports (12), medium inputs (10) and medium output (11).
3. detection according to claim 1 and drying device, it is characterized in that, described device has the support for fixing described dialyzer (1) in the mode that can get loose, and, at least one adapter cover (5) is connected on the driver (6) of orthoscopic effect, thus described adapter cover (5) can be connected with described fixing dialyzer (1) hermetically, or can get loose from described dialyzer.
4. detection according to claim 1 and drying device, it is characterized in that, in order to detect described dialyzer (1), described control device is connected on the manipulation device of described valve (7) as follows, namely, at least one interface in the interface of described adapter cover (5) and/or at least one dislysate interface (8) are the interfaces for air input (9) or medium input (10), at least one other interface of described adapter cover (5) and/or at least one dislysate interface (8) are the interfaces exporting (12) or medium output (11) for air, and close other valves (7).
5. detection according to claim 1 and drying device, is characterized in that, in order to the described dialyzer of drying (1), described control device is connected on the manipulation device of described valve (7) as follows,
The interface of-described first adapter cover (5a) is the interface for air input (9),
The interface of-described second adapter cover (5b) is the interface exporting (12) for air,
-at least one dislysate interface (8) is the dislysate interface (8) for air input (9),
-at least one dislysate interface (8) is the dislysate interface (8) exporting (12) for air, and
-close other valves (7).
6. detection according to claim 1 and drying device, is characterized in that, the device (2) of described generation air flowing is the device (2) producing hot-air.
7. detection according to claim 6 and drying device, is characterized in that, the device (2) of described generation hot-air is the compressor (2) with follow-up air heat.
8. detection according to claim 1 and drying device, is characterized in that, described medium source (3) is media Containers (3).
9. detection according to claim 1 and drying device, is characterized in that, described medium is water.
10. detection according to claim 1 and drying device, it is characterized in that, in order to monitor aridity, temperature sensor and/or humidity sensor are connected to the circuit exporting (12) for air, thus can know the temperature and/or humidity that flow out air.
11. detection according to claim 10 and drying devices, is characterized in that, temperature sensor and/or the humidity sensor of the described circuit for air output (12) are connected with described control device.
CN201480002012.6A 2013-02-25 2014-02-25 Detection and drying device for carrying out Function detection to dialyzer Active CN104507553B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102013203082.7 2013-02-25
DE102013203082.7A DE102013203082B4 (en) 2013-02-25 2013-02-25 Testing and drying device for functional testing of dialyzers
PCT/EP2014/053607 WO2014128306A1 (en) 2013-02-25 2014-02-25 Testing and drying device for testing the function of dialysers

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CN104507553A true CN104507553A (en) 2015-04-08
CN104507553B CN104507553B (en) 2017-06-09

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DE (1) DE102013203082B4 (en)
WO (1) WO2014128306A1 (en)

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DE102013203082A1 (en) 2014-08-28
CN104507553B (en) 2017-06-09
WO2014128306A1 (en) 2014-08-28

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