CN104958577A - Traditional Chinese medicine composition for treating facial paralysis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating facial paralysis and preparation method thereof Download PDF

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Publication number
CN104958577A
CN104958577A CN201510475732.0A CN201510475732A CN104958577A CN 104958577 A CN104958577 A CN 104958577A CN 201510475732 A CN201510475732 A CN 201510475732A CN 104958577 A CN104958577 A CN 104958577A
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rhizoma
chinese medicine
medicine composition
facial paralysis
borneolum syntheticum
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向美润
向国强
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Abstract

The invention discloses a traditional Chinese medicine composition for treating facial paralysis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the raw materials of giant typhonium rhizome, white silkworm, scorpion, Szechuan lovage rhizome, tall gastrodia tuber, jackinthepulpit tuber, centipede, Chinese angelica and borneol by the steps of drying and then grinding the raw materials into fine powder according to different characteristics of the raw materials, and dissolving the borneol by using white spirit; and uniformly mixing the dissolved borneol with the fine powder, and performing shaping, drying and sterilization to prepare pills. The traditional Chinese medicine composition for treating the facial paralysis, disclosed by the invention, is easily-available in raw materials, simple in preparation process, and convenient to take, does not have toxic or side effects, takes effect quickly, can position indications, and is low in manufacturing cost.

Description

Chinese medicine composition of a kind of facial paralysis and preparation method thereof
Technical field
The invention belongs to tcm field, relate to Chinese medicine composition of a kind of facial paralysis and preparation method thereof.
Background technology
Facial paralysis is many by positive QI-insufficiency, and venation is hollow, weakened defensive QI, and ailment said due to cold or exposure is taken advantage of a weak point in opponent's defence into apoplex involving the channels and collaterals, causes QI and blood numbness to hinder, facial shaoyang meridians network, and Yangming Channel muscle loses in moistening foster, so that muscle vertical delaying does not receive and send out primary disease.The cause of disease is the formations such as wind and cold damp-phlegm void.Pathogenesis is positive QI-insufficiency, and venation is hollow.Weakened defensive QI wind-cold damp pathogen is taken advantage of a weak point in opponent's defence and is invaded, and cause stagnation of QI-blood numbness to hinder, facial passages through which vital energy circulates loses in needing hair care to be facial paralysis.According to the etiology and pathogenesis of facial paralysis, Therapeutic Principle is: dispelling pathogenic wind and eliminating phlegm, dispelling cold by warming the meridian, dredge the meridian passage, dehumidifying relieving convulsion, invigorating QI and blood.
In prior art, denomination of invention is a kind of Chinese invention patent of Chinese medicine of facial paralysis, Shen publication number is CN101773585A, it is by the Radix Angelicae Dahuricae, Bombyx Batryticatus, Rhizoma Arisaematis, Fructus Arctii, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Flos Carthami, Radix Glycyrrhizae Preparata, Fructus Cannabis, Lignum Sappan, Scorpio, Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, the Radix Linderae, Radix Paeoniae Rubra, Retinervus Luffae Fructus 16 herbal medicine forms, its compatibility complex structure, lack unity and coherence, Fructus Arctii heat-clearing and toxic substances removing, Fructus Cannabis loosening bowel to relieve constipation, crow Chinese herbaceous peony regulating QI to relieve pain, the etiology and pathogenesis of these medicines and facial paralysis is inconsistent, and full side's expelling wind to relieve convulsion medicine is few, drug effect is not strong, activating blood and removing stasis drug is laid particular stress on.
Denomination of invention is a kind of Chinese invention patent of Chinese medicine composition of facial paralysis, publication number is CN103223006A, it is made up of Bombyx Batryticatus, Semen Sinapis, Scolopendra, Radix Glycyrrhizae 4 herbal medicine, be only applicable to the facial paralysis caused by wind-phlegm mild, and the deficiency and coldness cause of disease of facial paralysis has no Drug therapy, compatibility is simple, and the etiology and pathogenesis for facial paralysis is incomplete.
Denomination of invention is a kind of Chinese invention patent of Chinese medicine composition of facial paralysis, publication number is CN103223118A, and it is made up of Radix Puerariae, Ramulus Cinnamomi, Rhizoma Gastrodiae, Radix Scutellariae, the Radix Paeoniae Alba, Rhizoma Typhonii, Bombyx Batryticatus, Periostracum Cicadae, Lignum Sappan, Cortex erythrinae, Rhizoma Cyperi, Flos Carthami, Rhizoma Chuanxiong, Pheretima, Retinervus Luffae Fructus, Fructus Arctii, Herba Taraxaci, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae Preparata 19 herbal medicine.Effect is clearing away heat and expelling wind, the pain that disappears relieving convulsion, blood circulation promoting and blood stasis dispelling, resolving depression eliminating stagnation.Etiology and pathogenesis in face paralysis do not relate to heat, bitterly, knot, only have void, cold, wind, expectorant, damp disease because of, antipyretic in side, the pain that disappears medicine, eliminating stagnation medicine not necessarily has effect to facial paralysis, and cold-evil can not use bitter cold, heat clearing away class medicine.
Summary of the invention
In view of the foregoing defects the prior art has, according to the etiology and pathogenesis of facial paralysis, provide a kind of there is dispelling pathogenic wind and eliminating phlegm, dispelling cold by warming the meridian, dredge the meridian passage, dehumidifying relieving convulsion, effect of invigorating QI and blood and easy to use, instant effect, good effect, have no side effect, the Chinese patent medicine of facial paralysis.
For achieving the above object, the present invention adopts following technical scheme:
A Chinese medicine composition for facial paralysis, the medicament that it is mainly made up of the raw material of Chinese medicine of following weight proportioning:
Rhizoma Typhonii 1-25, Bombyx Batryticatus 5-20, Scorpio 1-20, Rhizoma Chuanxiong 1-20, Rhizoma Gastrodiae 5-15, Rhizoma Arisaematis 5-20, Scolopendra 5-15, Radix Angelicae Sinensis 5-15, Borneolum Syntheticum 0.1-3.
The weight proportion scope preparing preferred each raw material of Chinese medicine composition of the present invention for for:
Rhizoma Typhonii 5-15, Bombyx Batryticatus 7-18, Scorpio 2-16, Rhizoma Chuanxiong 3-15, Rhizoma Gastrodiae 6-11, Rhizoma Arisaematis 7-14, Scolopendra 6-13, Radix Angelicae Sinensis 8-12, Borneolum Syntheticum 0.5-2.
The weight proportion of each raw material of the best of Chinese medicine composition of the present invention is:
Rhizoma Typhonii 10, Bombyx Batryticatus 10, Scolopendra 10, Scorpio 10, Rhizoma Gastrodiae 10, Rhizoma Arisaematis 10, Rhizoma Chuanxiong 10, Radix Angelicae Sinensis 10, Borneolum Syntheticum 0.5.
Chinese medicine composition of the present invention can adopt the customary preparation methods of Chinese medicine to prepare.By the preferred production method that above-mentioned each raw material of Chinese medicine makes Chinese medicine composition of the present invention be:
First get Rhizoma Typhonii, Bombyx Batryticatus, Scorpio, Rhizoma Chuanxiong, Rhizoma Gastrodiae, Rhizoma Arisaematis, Scolopendra, Radix Angelicae Sinensis, dry porphyrize powder 80 mesh sieve mistake; Borneolum Syntheticum Chinese liquor is dissolved; By Borneolum Syntheticum dissolving liquid and above-mentioned institute porphyrize powder Homogeneous phase mixing, molding, the temperature of 40-60 is dried, obtained pill.
The alcohol content of described Chinese liquor is 50-70%, preferred alcohol content 52%.
Compatibility principle of the present invention: Head And Face Foot yangming Channel arteries and veins holds choma lip under the arm, and meridian of Foot-TAI YANG arteries and veins arises from shame in order, stores expectorant turbid in Yangming Channel, in wind during the sun is outer, wind-phlegm hinders in women's head-ornaments meridians, cold main spasm, then unfavorable through then, and muscles loses supports, therefore need not and delay; Naivete part, QI and blood still can be run, relatively anxious, and slow person is anxious person traction, therefore facial hemiparalysis.Control suitable dispelling pathogenic wind and eliminating phlegm, dispelling cold by warming the meridian, dredge the meridian passage, dehumidifying relieving convulsion, invigorating QI and blood.Rhizoma Typhonii, pungent, loose, dispelling pathogenic wind and eliminating phlegm in side, dispelling cold by warming the meridian, is also longer than the wind for the treatment of women's head-ornaments; Bombyx Batryticatus, Scorpio all can be expellingged wind and relieving convulsion, and wherein Bombyx Batryticatus has resolve phlegm effect concurrently, and Scorpio is good at dredging collateral, and three medicines share, and the efficacy of a drug is specially imitated significantly, for wind-phlegm hinders in women's head-ornaments, and meridians and establishing, the QIANZHENGSAN of original name " Young man Tibetan side "; Scolopendra joins Scorpio, dispelling pathogenic wind and eliminating phlegm, and the effect of stimulating the menstrual flow is strong, and original name is Zhijing San, and four medicines are monarch; Rhizoma Gastrodiae, Rhizoma Arisaematis dispelling pathogenic wind and eliminating phlegm are minister, Chinese angelica blood supplementing nourishing blood and promoting blood circulation, and Rhizoma Chuanxiong is invigorated blood circulation, and priming goes directly disease institute, and Borneolum Syntheticum causing resuscitation with aromatic drugs, it is adjuvant.
Pharmacology analysis of the present invention, Rhizoma Typhonii is containing multiple alkaloid, and wherein with aconitine, mesaconitine, hypaconitine is main, and raw with having expelling wind to relieve convulsion, effect of dispelling cold by warming the meridian, has analgesia, antiinflammatory, cold resistance, the pharmacological action such as make sensory nerve end slightly excited; Bombyx Batryticatus is containing the composition such as protein, fat, and contained protein has the pharmacological action of cortex in stimulation of renal, has dispelling pathogenic wind and eliminating phlegm, determines effect of convulsion; Scorpio contains charybdotoxin, for the toxic protein of the elements such as a kind of carbon containing, hydrogen, oxygen, chlorine, sulfur and Serpentis and toxin Nervous toxicity similar, and containing trimethylammonium, taurine, palmitic acid, stearic acid, cholesterol, incubates the composition such as phospholipid, ammonium salt, have significantly lasting convulsion spasmolytic, the pharmacological action such as relieve dizziness, high fever, infantile convulsions, epilepsy, etc.; Scolopendra contains the two kind noxious substances similar to Venenum apis and H-subst and dissolved blood protein matter, and containing tyrosine, the compositions such as leucine, formic acid, fatty oil, cholesterol, has that spasmolytic relieves dizziness, high fever, infantile convulsions, epilepsy, etc., detoxifies, the pharmacological action such as antibacterial; Rhizoma Gastrodiae containing gastrodine, gastrodin, succinic acid, Palmic acid, the compositions such as polysaccharide, have suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., relieving convulsion, analgesia, the pharmacological action such as antiinflammatory; Rhizoma Arisaematis containing Saponin, benzoic acid, the compositions such as phlegmatic temperament and volume starch, eliminate the phlegm, spasmolytic, the pharmacological action such as analgesia; Rhizoma Chuanxiong is containing the composition such as ligustrazine and ferulic acid.Have blood vessel dilating, reduce tremulous pulse and crown arteries and veins resistance, the pharmacological actions such as antithrombus formation spasmolytic, ligustrazine, by brain barrier, improves brain intensive amount, has blood-activating and qi-promoting, effect of wind-expelling pain-stopping; Radix Angelicae Sinensis is containing compositions such as acid Wei, nicotinic acid, uracil, polysaccharide, and having enriches blood invigorates blood circulation, effect of loosening bowel to relieve constipation, has anticoagulant, antithrombotic, hemopoietic and anti-anemia pharmacological action, also has antiinflammatory, resisting fatigue, the effect of anti-hypoxia.Borneolum Syntheticum causing resuscitation with aromatic drugs, priming enters network.
The present invention be the cause of disease according to facial paralysis (wind and cold, wet, expectorant, void) pathogenesis (muscle BI-syndrome involved the blood vessels hinders, muscles lose moisten foster) and design.Compatibility science, primary and secondary is clear, and classical prescription adds experience and combines, and is used for the treatment of facial paralysis.There is dispelling pathogenic wind and eliminating phlegm, dispelling cold by warming the meridian, dehumidifying relieving convulsion, effect of invigorating QI and blood.Through taking in the examination of the thousands of routine patient of hospital clinical, effective percentage 100%, cure rate 97%.Its raw materials is easy to get, and preparation technology is simple, and taking convenience, has no side effect, instant effect, and indication is located, low cost of manufacture.
Detailed description of the invention
Below in conjunction with detailed description of the invention, summary of the invention of the present invention is described in further detail.Should understand, embodiments of the invention only unrestricted the present invention for illustration of the present invention, when not departing from the technology of the present invention thought, according to ordinary skill knowledge and customary means, the various replacement made and change, all should comprise within the scope of the invention.
(1) embodiment
Raw material (kilogram) is taken by following proportioning:
1. Rhizoma Typhonii 5, Bombyx Batryticatus 18, Scorpio 2, Rhizoma Chuanxiong 15, Rhizoma Gastrodiae 6, Rhizoma Arisaematis 14, Scolopendra 6, Radix Angelicae Sinensis 12, Borneolum Syntheticum 0.5.
2. Rhizoma Typhonii 15, Bombyx Batryticatus 7, Scorpio 16, Rhizoma Chuanxiong 3, Rhizoma Gastrodiae 11, Rhizoma Arisaematis 7, Scolopendra 13, Radix Angelicae Sinensis 8, Borneolum Syntheticum 2.
3. Rhizoma Typhonii 10, Bombyx Batryticatus 10, Scorpio 10, Rhizoma Chuanxiong 10, Rhizoma Gastrodiae 10, Rhizoma Arisaematis 10, Scolopendra 10, Radix Angelicae Sinensis 10, Borneolum Syntheticum 0.5.
4. Rhizoma Typhonii 25, Bombyx Batryticatus 20, Scorpio 1, Rhizoma Chuanxiong 1, Rhizoma Gastrodiae 5, Rhizoma Arisaematis 20, Scolopendra 15, Radix Angelicae Sinensis 5, Borneolum Syntheticum 3.
5. Rhizoma Typhonii 1, Bombyx Batryticatus 5, Scorpio 20, Rhizoma Chuanxiong 20, Rhizoma Gastrodiae 15, Rhizoma Arisaematis 5, Scolopendra 5, Radix Angelicae Sinensis 15, Borneolum Syntheticum 0.1.
6. Rhizoma Typhonii 3, Bombyx Batryticatus 5, Scorpio 5, Rhizoma Chuanxiong 6, Rhizoma Gastrodiae 5, Rhizoma Arisaematis 8, Scolopendra 5, Radix Angelicae Sinensis 8, Borneolum Syntheticum 0.1.
7. Rhizoma Typhonii 20, Bombyx Batryticatus 18, Scorpio 18, Rhizoma Chuanxiong 15, Rhizoma Gastrodiae 12, Rhizoma Arisaematis 15, Scolopendra 15, Radix Angelicae Sinensis 12, Borneolum Syntheticum 1.
Production method is as follows: first get Rhizoma Typhonii, Bombyx Batryticatus, Scorpio, Rhizoma Chuanxiong, Rhizoma Gastrodiae, Rhizoma Arisaematis, Scolopendra and Radix Angelicae Sinensis, dries porphyrize powder, 80 mesh sieve mistakes; The Chinese liquor (preferred alcohol content is 52%) of Borneolum Syntheticum alcohol content 50-70% is dissolved; By Borneolum Syntheticum dissolving liquid and above-mentioned institute porphyrize powder Homogeneous phase mixing, molding, dries by the temperature of 40-60 degree, packaging, sealing, obtained pill.
(2) model case
Case 1, Lee, man, 63 years old, morning, WA felt suddenly left side facial numbness, weak, mouth is to the right askew, and can not close, eye face can not close, be diagnosed as facial paralysis through certain Grade A hospital, give symptomatic treatment 7 days, have no improvement, going to a doctor in here of coming for 8th day, according to symptom, sign, is diagnosed as facial paralysis, the Chinese patent medicine of oral a kind of facial paralysis of the present invention, after one week, symptom is clearly better, recovery from illness in 3 weeks.
Case 2, for certain, female, 45 years old, facial paralysis one month, gave the treatments such as acupuncture-moxibustion physical therapy through certain hospital's acupuncture-moxibustion department of physiotherapy, 2 weeks, has no improvement, and going to a doctor in here of coming for the 3rd week, is facial paralysis according to the state of an illness, symptom, diagnostic sign.The Chinese patent medicine of oral a kind of facial paralysis of the present invention, after after one week, symptom is clearly better, and fully recovers after January.
Case 3, Cai, man, 68 years old, because of Hemorrhagic strokes, rescues through certain hospital, after symptomatic treatment first quarter moon, stable disease, but leave sequela, disease sees that right side eye can not close, and facial hemiparalysis, facial muscular strength is III level, is diagnosed as the facial paralysis of apoplexy future trouble disease.The Chinese patent medicine of oral a kind of facial paralysis of the present invention, after 2 weeks, symptom is clearly better, and within 6 weeks, cures completely.

Claims (7)

1. a Chinese medicine composition for facial paralysis, is characterized in that: the medicament that it is mainly made up of the raw material of Chinese medicine of following weight proportioning:
Rhizoma Typhonii 1-25, Bombyx Batryticatus 5-20, Scorpio 1-20, Rhizoma Chuanxiong 1-20, Rhizoma Gastrodiae 5-15, Rhizoma Arisaematis 5-20, Scolopendra 5-15, Radix Angelicae Sinensis 5-15, Borneolum Syntheticum 0.1-3.
2. the Chinese medicine composition of a kind of facial paralysis as claimed in claim 1, is characterized in that: wherein the weight proportion of each raw material is:
Rhizoma Typhonii 5-15, Bombyx Batryticatus 7-18, Scorpio 2-16, Rhizoma Chuanxiong 3-15, Rhizoma Gastrodiae 6-11, Rhizoma Arisaematis 7-14, Scolopendra 6-13, Radix Angelicae Sinensis 8-12, Borneolum Syntheticum 0.5-2.
3. the Chinese medicine composition of a kind of facial paralysis as claimed in claim 1, is characterized in that; Wherein the weight proportion of each raw material is:
Rhizoma Typhonii 10, Bombyx Batryticatus 10, Scolopendra 10, Scorpio 10, Rhizoma Gastrodiae 10, Rhizoma Arisaematis 10, Rhizoma Chuanxiong 10, Radix Angelicae Sinensis 10, Borneolum Syntheticum 0.5.
4. the Chinese medicine composition of a kind of facial paralysis as described in claim 1 or 2 or 3, is characterized in that: described medicament is pill.
5. the preparation method of the Chinese medicine composition of facial paralysis described in claim 1 or 2 or 3 or 4, is specially: first get Rhizoma Typhonii, Bombyx Batryticatus, Scorpio, Rhizoma Chuanxiong, Rhizoma Gastrodiae, Rhizoma Arisaematis, Scolopendra, Radix Angelicae Sinensis, dries porphyrize powder, 80 mesh sieve mistakes; Borneolum Syntheticum Chinese liquor is dissolved; By Borneolum Syntheticum dissolving liquid and above-mentioned institute porphyrize powder Homogeneous phase mixing, molding, the temperature of 40-60 is dried, obtained pill.
6. the preparation method of the Chinese medicine composition of facial paralysis as claimed in claim 5, is characterized in that: the alcohol content of described Chinese liquor is 50-70%.
7. the preparation method of the Chinese medicine composition of facial paralysis as claimed in claim 6, is characterized in that: the alcohol content of described Chinese liquor is 52%.
CN201510475732.0A 2015-08-06 2015-08-06 Traditional Chinese medicine composition for treating facial paralysis and preparation method thereof Pending CN104958577A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101045117A (en) * 2006-03-30 2007-10-03 赵云志 Traditional Chinese medicine cream for treating facial paralysis
CN102670998A (en) * 2012-05-08 2012-09-19 成都绿迪科技有限公司 Traditional Chinese medicine for treating facial paralysis
CN103520543A (en) * 2013-10-19 2014-01-22 张振杰 Traditional Chinese medicinal composition for treating facioplegia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101045117A (en) * 2006-03-30 2007-10-03 赵云志 Traditional Chinese medicine cream for treating facial paralysis
CN102670998A (en) * 2012-05-08 2012-09-19 成都绿迪科技有限公司 Traditional Chinese medicine for treating facial paralysis
CN103520543A (en) * 2013-10-19 2014-01-22 张振杰 Traditional Chinese medicinal composition for treating facioplegia

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
付志强 等: "中西医结合治疗贝尔氏面瘫疗效观察", 《实用中西医结合临床》 *

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Application publication date: 20151007