CN104946453A - Preparation and use method of health drug wheat koji - Google Patents

Preparation and use method of health drug wheat koji Download PDF

Info

Publication number
CN104946453A
CN104946453A CN201510290999.2A CN201510290999A CN104946453A CN 104946453 A CN104946453 A CN 104946453A CN 201510290999 A CN201510290999 A CN 201510290999A CN 104946453 A CN104946453 A CN 104946453A
Authority
CN
China
Prior art keywords
wheat
wheat koji
parts
bent
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201510290999.2A
Other languages
Chinese (zh)
Other versions
CN104946453B (en
Inventor
周宝龙
肖玉祥
周浦益
王�华
吴东平
张建国
朱政羌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHAANXI QINYANG CHANGSHENG WINERY CO Ltd
Original Assignee
SHAANXI QINYANG CHANGSHENG WINERY CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHAANXI QINYANG CHANGSHENG WINERY CO Ltd filed Critical SHAANXI QINYANG CHANGSHENG WINERY CO Ltd
Priority to CN201510290999.2A priority Critical patent/CN104946453B/en
Publication of CN104946453A publication Critical patent/CN104946453A/en
Application granted granted Critical
Publication of CN104946453B publication Critical patent/CN104946453B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/02Preparation of other alcoholic beverages by fermentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12JVINEGAR; PREPARATION OR PURIFICATION THEREOF
    • C12J1/00Vinegar; Preparation or purification thereof

Abstract

The invention relates to a preparation method of a health drug wheat koji, and belongs to the technical field of brewage fermentation. The method is characterized in that 1100-1200 parts of wheat, 10-15 parts of unprepared hawthorn fruit, 20-25 parts of Polygonatum sibiricum, 10-12 parts of dry lotus leaf, 11-12 parts of chrysanthemum, 15-20 parts of wolfberry fruit, 6-8 parts of cape jasmine , 5-7 parts of peach seed, 5-6 parts of Radix Puerariae, 5-6 parts of cassia seed, 5-7 parts of licorice root, 5-10 parts of a mother starter and a proper amount of water are mixed and cultured to prepare a drug wheat mother starter, the average saccharification power of the drug wheat koji is 1235.06U/g and is 38% higher than that of wheat koji free from traditional Chinese medicinal materials (blank control), and the average general flavone content of the drug wheat koji reaches 164.5mg/100g; and the general flavone content of yellow rice wine brewed by using the drug wheat koji reaches 112.78mg/100ml, and is 1.48 times that of blank control yellow rice wine. The drug wheat koji produced in the invention is rich in flavonoid compounds which are blood fat reducing active components, can comprehensively adjust the functions of the human cardiovascular system, and has clear drug effect and action mechanism.

Description

A kind of health care medicinal wheat koji makes and using method
Technical field
The present invention relates to a kind of health care medicinal wheat koji to make and using method, belong to and brewage fermentation technical field.
Background technology
Song is saccharifying agent, the starter of brewageing diet product, is divided into little song (yeast for brewing rice wine), wheat koji and red colouring agent for food, also used as a Chinese medicine from raw material, is divided into again dosing song and bent two kinds of not dosing.Medicine song has long history, adds the effect that Chinese medicinal materials mainly contains two aspects in yeast-making technology, and one is the fragrance and the trophic function that improve wine, two be promote microorganism fertility metabolism and domestication (Zhou Henggang koji is used as medicine [J], brewing science and technology, 1999,04:5-6).
Research shows, Chinese medicinal materials contains the biologically active substances such as flavonoid compound, alkaloid, polysaccharide, volatile oil, tannin, organic acid, these biologically active substances have sterilization, antibacterial, conditioner body immunity function and metabolism, improve the effect of human health level.Flavonoid compound (flavonoid) is also known as flavonoids, BIOFLAVONOLDS; it is the element of the first species distributed more widely in vegitabilia; there is the effect of the functions such as anti-oxidant, anti-inflammatory, anti-allergic and raising immunity of organisms and control chronic degenerative diseases; a large amount of cell culture studies and results of animal all show; some flavonoid substances also have stronger antimicrobial, chelated metal ions, protection DNA, suppress the effects such as low-density lipoprotein (LDL) oxidation and growth of tumour cell.Its physiologically active of flavonoid compound is various, and reducing blood-fat realizes mainly through antioxygenation, and in On behalf of plant, hawthorn is parts of generic medicinal plants, and main is main flavonoid organic acid containing Quercetin 3-galactoside, obviously can reduce mice serum TC and raise HDL-TC.The production method of traditional drugs song is similar to the production of conventional brew Daqu and little song, microbe-derived in medicine song propagates in inoculation or original bent powder naturally, produces conversion to a certain degree and the healthy food material of the quasi-tradition Chinese medicinal materials made or medicine-food two-purpose by the spontaneous fermentation of microorganism to the primary characteristic of starter-making materials.Along with the development of modern fermentation technique and bio-science technology, fundamental research and the application and development thereof of middle traditional Chinese medicines song will develop rapidly, and medicinal bent class becomes an important branch of China's Chinese Traditional Medicine and field of health care food just gradually.
With medicine-food two-purpose be at present the Chinese medicinal materials medicine of raw material bent mostly adopt Chinese medicinal materials to be added in starter-making materials obtain, its shortcoming does not have quantitative analysis comparative study, and cause the effective ingredient of Chinese medicinal materials to run off in a large number, drug effect is not good.The present invention relates to a kind of health care medicinal wheat koji to make and using method, there is with interpolation in wheat yeast making process the dietotherapeutic Chinese medicinal materials of hypolipemic function, the quasi-tradition Chinese medicine made by the spontaneous fermentation of microorganism or the healthy food material of medicine-food two-purpose, and the diet product that the taste using this medicine song to manufacture is abundant.Bent for medicine traditional to wheat koji technology of preparing and China concept combines by the present invention, and preparation at present has the medicine wheat koji of antilipemic healthy functional active components and using method at home and abroad have not been reported.
Summary of the invention
For above technology Problems existing, the invention provides a kind of health care medicinal wheat koji and make and using method.
The present invention solves the problems of the technologies described above adopted technical scheme:
By research koji and herbal pharmacology, chemical composition, carry out the screening of active drug, to draw up out the formula of medicine of lipid-reducing function composition, there is with interpolation in wheat yeast making process the dietotherapeutic Chinese medicinal materials of hypolipemic function, to improving saccharogenic power and the physical and chemical index of medicine wheat koji, make the reducing blood-fat effective active composition containing Chinese medicinal materials in the medicine wheat koji finally made and the diet product using this medicine song to manufacture simultaneously, make medicine song and leavened prod thereof have certain nourishing function.A kind of health care medicinal wheat koji makes and using method, and wherein said raw material number, except specified otherwise, is parts by weight, is made up of following raw material:
Wheat 1100-1200, Fructus Crataegi 10-15, sealwort 20-25, dried waterlily leaf 10-12, chrysanthemum 11-12, wolfberry fruit 15-20, cape jasmine 6-8, peach kernel 5-7, root of kudzu vine 5-6, Semen Cassiae 5-6, Radix Glycyrrhizae 5-7, plant bent 5-10, water is appropriate.
In this Chinese medicine formula, Fructus Crataegi, taste acid is sweet, slightly warm in nature, return taste Liver Channel, the traditional Chinese medical science is used for promoting digestion and removing indigestion, promoting blood circulation to remove blood stasis, containing pycnogenols, take Quercetin as the flavonoid compound of representative, triterpene compound and organic acid, there is cardiac stimulant, increase coronary blood flow, improve the effects such as blood circulation;
Sealwort, can be nourishing Yin and moistening lung, tonifying spleen benefit stomach, containing functional components such as sealwort saponin, flavonoid compound and polygonatum polysaccharides, has protection cardiovascular and cerebrovascular, reduces blood fat, reduces blood sugar, enhancing body immunologic function;
Lotus leaf, there is effect of clearing away summer heat, sending up the lucid YANG, cooling blood for hemostasis, be mainly used in hot summer weather polydipsia, diarrhea due to summer heat and dampness, blood-head tells nosebleed, the diseases such as uterine bleeding of having blood in stool, mainly containing alkaloid, flavones, volatilization wet goods composition, wherein the biological activity of flavones and alkaloid compound is higher, has regulating lipid and reducing weight, antioxidant and anti-aging, bacteriostatic action;
Chrysanthemum, dispelling wind, heat-clearing, improving eyesight, removing toxic substances, controls headache, dizzy, hot eyes, ambition dysphoria with smothery sensation, furunculosis, pyogenic infections.Containing VITAMIN B4, choline, stachydrine and chrysanthemum glucoside, flavonoid functional component, there is hypotensive effect to hyperpietic;
Matrimony vine, taste is sweet, property is flat, containing multiple nutritional components such as matrimony vine protein-polysaccharide, vitamins C, phosphorus, iron, has nourishing YIN and supplementing blood, the effects such as replenishing vital essence to improve eyesight;
Cape jasmine, there is effects such as protecting liver, cholagogic, step-down, calmness, hemostasis, detumescence, containing flavonoid gardenin, pectin, tannin, crocin, crocetin, PEARLITOL 25C, nonacosane, β-sitosterol, the another glucoside containing the smelly formaldehyde structure of multiple tool ring: gardenoside, geniposide pool element-1-glycoside, lattice Tegosept P-1-β-D-gentiobioside and mountain Cape jasmine in a small amount, be usually used in the diseases such as treatment icterohepatitis, sprain and contusion, hypertension, diabetes at tcm clinical practice;
Peach kernel, sweet flat, the bitter of property, enters lung, liver, large intestine channel, has promoting blood circulation to remove blood stasis, effect of relaxing bowel effect.For through closing, dysmenorrhoea , wei lump in the abdomen lump in the abdomen, injury from falling down, the dry constipation of intestines.The main component of peach kernel, containing compounds such as Vitamin B17, sterol, flavonoid, phenolic acids, proves that it has the pharmacological actions such as anticoagulation, antithrombotic, prevention hepatic fibrosis and strengthening immunity;
The root of kudzu vine, taste is sweet, pungent, and property is put down, flavonoid compound is planted containing soybean (soya bean) glucoside, daidzein, puerarin etc. more than 10, and containing daucosterol, amino acid, coumarins etc., cure the wound cold, warm headache Xiang Qiang, and dysphoria with smothery sensation is quenched one's thirst, have loose bowels, dysentery, ecchymosis is not saturating, hypertension, stenocardia, deaf;
Semen Cassiae, Semen Cassiae taste is sweet, bitter, salty, cold nature, is apt to, into liver, kidney, large intestine channel, have the effect of clearing liver and improving vision, relaxing bowel.Main component is that anthraquinone component accounts for 1%.Semen Cassiae has better reducing blood-fat, hypotensive, anti-oxidant, anti-ageing curative effect of waiting for a long time.Modern pharmacology research shows, Semen Cassiae suppresses the effect of serum cholesterol rising and atherosclerotic plaque, and lipid-lowering effect is remarkable;
Radix Glycyrrhizae, by effect of its tonifying Qi benefit spleen and middle emergency, coordinating the actions of various ingredients in a prescription, main in Radix Glycyrrhizae have and have anti-inflammatory action containing material compositions such as Potenlini, Liquiritin and flavones, use the fragrance simultaneously increasing fermented wine in distiller's yeast, improves denseness and the color and luster of wine.
A kind of health care medicinal wheat koji of the present invention makes and using method, and each raw material drug matching is scientific and reasonable, and dosage is applicable to, and effective constituent can be discharged in goods by each Chinese medicinal materials.
A kind of health care medicinal wheat koji makes and using method, and concrete implementation step is:
(1) pre-treatment of Chinese medicinal materials
The preparation of a, Chinese medicinal materials medicinal powder
With pulverizer, Chinese medicinal materials is pulverized, for subsequent use after crossing 60 ~ 70 mesh sieve;
Boiling of b, Chinese medicinal materials concoction
Hawthorn, sealwort, the root of kudzu vine, Radix Glycyrrhizae are thinly sliced, dried waterlily leaf is ground into 2 × 2cm size, peach kernel, cape jasmine, Semen Cassiae are rolled into flap, powder 1 ~ 2cm was flooded with chrysanthemum, wolfberry fruit mixing and water adding, then micro-infusion 30 ~ 40min that boils, filtration obtains concoction, uses clear water infusion medicine 3 times continuously, filtrate is mixed, filtrate parts by weight 200 ~ 300, save backup;
(2) wheat crushing
Wheat-flour is broken into plum blossom limb shape, the fine powder controlling below 30 orders accounts for the 5-10% of wheat materials;
(3) interpolation of Chinese medicinal materials
Above-mentioned pulverizing wheat is added kind of a song, middle drug filtrate or traditional Chinese medicine powder in proportion, and water is appropriate, and control the 38-40% that ingredient water weight accounts for total raw material, mix is even;
(4) song, trick layer culture is stepped on
By above-mentioned bent material Qu Mo, manually step on and make curved billet, put into room temperature 15-25 DEG C, mould cultivation 5-7d on the bent room of humidity 70 ~ 80%, use bent room to ventilate or turn over bent way, control product temperature is at 40-45 DEG C, turn over bent 1 time every 12h during this, when turning over song, exchange is carried out at upper and lower position and inside and outside position curved billet and cultivate, make in curved billet evenly mould; After upper mould end, enter and support the bent stage, curved billet is barricaded as the bent frame of spacing 3-5cm, bent room humid control, 50 ~ 60%, turns over bent 1 time every 5d during this, and turn over after bent 3 times, curved billet enters seasoning, can enter storage etc. after curved billet drying.This song can be used for the brew for food such as yellow rice wine, vinegar, soy sauce.
Tool of the present invention has the following advantages:
1, medicine wheat koji is compared with the wheat koji (blank) not adding Chinese medicinal materials, the average glycated power 1235.06U/g dry medium of medicine wheat koji, the average glycated power 895.2U/g dry medium of blank wheat koji, and medicine wheat koji saccharogenic power improves 38%; Medicine wheat koji average total acid 0.61g/100g dry medium, blank wheat koji average total acid 0.85g/100g dry medium, medicine wheat koji total acid reduces by 28.0%; Medicine wheat koji average total flavones 164.5mg/100g dry medium, blank wheat koji average total flavones 68.62mg/100g dry medium, medicine wheat koji general flavone content is blank wheat koji 2.40 times, and therefore, nutritive value and the quality of medicine wheat koji are more excellent;
2, medicine wheat koji of the present invention is used for the brew in yellow rice wine, vinegar, soy sauce brewing food, the Chinese medicinal materials activeconstituents in diet product can be improved, concoction wheat koji yellow rice wine is compared with the wheat koji wine (blank) not adding Chinese medicinal materials, its alcoholic strength is 18.5%vol, alcoholic strength improves 1.0%, and the yield of liquor improves 4.45%, and total acid reduces by 13.8%, amino-acid nitrogen is 1.5 times of blank yellow rice wine, and non-saccharide solid is 0.32 times of blank yellow rice wine; Medicine wheat koji yellow rice wine general flavone content reaches 112.78mg/100ml, is 1.48 times of blank yellow rice wine; Nutritive value and the quality of medicine wheat koji yellow rice wine are more excellent;
3, the medicine wheat koji prepared of the inventive method and yellow rice wine medicine fragrant gentle, fragrant, containing flavonoid compound, polysaccharide, alkaloid hypolipidemic activity composition, have protect liver, cholagogic, kidney tonifying, invigorating the spleen and benefiting QI, promoting blood circulation and removing blood stasis and help digestion, eliminating phlegm, Li Shui effect and comprehensive adjustment cardiovascular system of human body, Digestive tract and function of immune system, drug effect and mechanism of action clear and definite.
Embodiment
Below by embodiment, the present invention is specifically described; what be necessary to herein means out is that the present embodiment is only used to further illustrate the present invention; but can not limiting the scope of the invention be interpreted as, some nonessential improvement and adjustment can be made according to the content of the invention described above.
Embodiment 1 health care medicinal wheat koji is produced
Be made up of following raw material:
Wheat 1150, Fructus Crataegi 10, sealwort 20, dried waterlily leaf 10, chrysanthemum 11, wolfberry fruit 15, cape jasmine 6, peach kernel 5, the root of kudzu vine 5, Semen Cassiae 5, Radix Glycyrrhizae 5, plant bent 8, water is appropriate.
(1) pre-treatment of Chinese medicinal materials
The preparation of a, Chinese medicinal materials medicinal powder
With pulverizer, Chinese medicinal materials is pulverized, for subsequent use after crossing 60 mesh sieve;
Boiling of b, Chinese medicinal materials concoction
Hawthorn, sealwort, the root of kudzu vine, Radix Glycyrrhizae are thinly sliced, dried waterlily leaf is ground into 2 × 2cm, peach kernel, cape jasmine, Semen Cassiae are rolled into flap, flooded powder 1 ~ 2cm with chrysanthemum, wolfberry fruit mixing and water adding, then micro-infusion 40min that boils, and filtered and obtain concoction, continuous clear water infusion medicine 3 times, filtrate is mixed, filtrate parts by weight 260, for subsequent use;
(2) wheat crushing
Wheat-flour is broken into plum blossom limb shape, the fine powder below 30 orders accounts for 6% of wheat materials;
(3) interpolation of Chinese medicinal materials
Above-mentioned pulverizing wheat is added the sort of quyi, middle drug filtrate or traditional Chinese medicine powder in proportion, and water is appropriate, and control ingredient water weight and account for 40% of total raw material, mix is even;
(4) song, trick layer culture is stepped on
Above-mentioned song material is manually stepped on bent mould and makes curved billet, put into room temperature 15-25 DEG C, mould cultivation 6d on the bent room of humidity 70 ~ 80%, use bent room to ventilate or turn over bent way and control product temperature at 40-45 DEG C, bent 1 time is turned over every 12h during this, when turning over song, exchange is carried out at upper and lower position and inside and outside position curved billet to cultivate, make in curved billet evenly mould; After upper mould end, enter the foster bent stage, curved billet is barricaded as the bent frame of spacing 3-5cm, bent room humid control, 50 ~ 60%, turns over bent 1 time every 5d during this, and turn over after bent 3 times, curved billet enters seasoning, the obtained Chinese medicinal materials wheat koji etc. curved billet drying.
(5) the concoction wheat koji obtained and medicinal powder wheat koji are carried out saccharogenic power, total acid, moisture mensuration, measurement result is shown among table 1.
Table 1 concoction wheat koji, medicinal powder wheat koji and each physical and chemical index of blank wheat koji contrast
As can be seen from Table 1, the Chinese medicinal materials wheat koji obtained according to method provided by the invention with compared with the wheat koji (blank) not adding Chinese medicinal materials, use add Chinese medicinal materials mode more excellent; Concoction wheat koji is compared with medicinal powder wheat koji, and concoction wheat koji saccharogenic power, total flavones are higher than medicinal powder wheat koji, and acid is lower than medicinal powder wheat koji, therefore, when using method of the present invention to prepare medicine song, uses the mode of adding concoction more excellent.
Embodiment 2 concoction wheat koji and do not add wheat koji (blank) the brewageing for yellow rice wine of Chinese medicinal materials
Use the concoction wheat koji of embodiment 1 to manufacture yellow rice wine, use the wheat koji (blank) not adding Chinese medicinal materials to brewage yellow rice wine in contrast by identical technique simultaneously.Method steps comprises rice dipping, steamed rice, and fermentation forms, specific as follows:
(1) feed intake and ferment
Raw material steams: glutinous rice add water eluriate after soak at room temperature 24h, steam rice without the white heart, stand be chilled to 25-27 DEG C with;
Ferment yellow wine fermentation technology controlling and process routinely, fermentation batches parts by weight are composed as follows:
Glutinous rice 50, black rice 30, scented rice 20, active dry yeast 0.1, water 170, concoction wheat koji 12 or blank wheat koji 12
(2) yellow rice wine physical and chemical index detected result is in table 2
Table 2 concoction wheat koji yellow rice wine contrasts with each physical and chemical index of wheat koji (blank) yellow rice wine not adding Chinese medicinal materials
As can be seen from Table 2, the alcoholic strength of concoction wheat koji yellow rice wine, the yield of liquor, amino-acid nitrogen, non-saccharide solid, total flavones are higher than blank wheat koji 2 yellow rice wine, and acid, total reducing sugar is lower than blank wheat koji 2 yellow rice wine, namely the nutritive value of the bent yellow rice wine of medicine and quality more excellent, illustrates and uses the distiller's yeast of the medicine Qu Zuowei yellow rice wine brewage of the present invention's making to have obvious advantage.
The foregoing is only preferred embodiment of the present invention, all equalizations done according to the present patent application the scope of the claims change and modify, and all should belong to covering scope of the present invention.

Claims (3)

1. the present invention relates to a kind of health care medicinal wheat koji to make and using method, belong to and brewage fermentation technical field, its feature comprises the following steps:
(1) starter-making materials is made up of following parts by weight:
Wheat 1100-1200, Fructus Crataegi 10-15, sealwort 20-25, dried waterlily leaf 10-12, chrysanthemum 11-12, wolfberry fruit 15-20, cape jasmine 6-8, peach kernel 5-7, root of kudzu vine 5-6, Semen Cassiae 5-6, Radix Glycyrrhizae 5-7, plant bent 5-10, water is appropriate;
(2) pre-treatment of Chinese medicinal materials
The preparation of a, Chinese medicinal materials medicinal powder
With pulverizer, Chinese medicinal materials is pulverized, for subsequent use after crossing 60 ~ 70 mesh sieve;
Boiling of b, Chinese medicinal materials concoction
Hawthorn, sealwort, the root of kudzu vine, Radix Glycyrrhizae are thinly sliced, dried waterlily leaf is ground into 2 × 2cm, peach kernel, cape jasmine, Semen Cassiae are rolled into flap, flooded powder 1 ~ 2cm with chrysanthemum, wolfberry fruit mixing and water adding, then micro-infusion 30 ~ 40min that boils, and filtered and obtain concoction, continuous clear water infusion medicine 3 times, filtrate mixed, filtrate parts by weight 200 ~ 300, save backup;
(3) wheat crushing
Wheat grinding is pressed into plum blossom limb shape, the fine powder controlling below 30 orders accounts for the 5-10% of wheat materials;
(4) interpolation of Chinese medicinal materials
Above-mentioned pulverizing wheat is added the sort of quyi, middle drug filtrate or Chinese medicine powder in proportion, and water is appropriate, and control the 38-40% that ingredient water weight accounts for total raw material, mix is even;
(5) song, trick layer culture is stepped on
By above-mentioned bent material Qu Mo in step (4), manually step on and make curved billet, put into room temperature 15-25 DEG C, mould cultivation 5-7d on the bent room of humidity 70 ~ 80%, use bent room to ventilate or turn over bent way, control product temperature is at 40-45 DEG C, turn over bent 1 time every 12h during this, when turning over song, exchange is carried out at upper and lower position and inside and outside position curved billet and cultivate, make in curved billet evenly mould; After upper mould end, enter and support the bent stage, curved billet is barricaded as the bent frame of spacing 3-5cm, bent room humid control, 50 ~ 60%, turns over bent 1 time every 5d during this, and turn over after bent 3 times, curved billet enters seasoning, etc. can enter storage after curved billet drying;
(6) use of medicine wheat koji in wine brewing, vinegar, soy sauce making processes.
2. a kind of health care medicinal wheat koji according to claim 1 makes and using method, it is characterized in that the average glycated power 1235.06U/g dry medium of medicine wheat koji, the average glycated power of medicine wheat koji improves 38% with not adding compared with Chinese medicinal materials wheat koji (blank); The average general flavone content of medicine wheat koji reaches 164.5mg/100g dry medium.
3. a kind of health care medicinal wheat koji according to claim 1 makes and using method, it is characterized in that: in step (6), yellow wine fermentation raw material is made up of following parts by weight: glutinous rice 50, black rice 30, scented rice 20, active dry yeast 0.1, water 170, medicine wheat koji 12; Medicine wheat koji yellow rice wine general flavone content reaches 112.78mg/100ml, is 1.48 times of blank yellow rice wine.
CN201510290999.2A 2015-05-25 2015-05-25 A kind of production method of health care medicinal wheat koji Active CN104946453B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510290999.2A CN104946453B (en) 2015-05-25 2015-05-25 A kind of production method of health care medicinal wheat koji

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510290999.2A CN104946453B (en) 2015-05-25 2015-05-25 A kind of production method of health care medicinal wheat koji

Publications (2)

Publication Number Publication Date
CN104946453A true CN104946453A (en) 2015-09-30
CN104946453B CN104946453B (en) 2018-06-08

Family

ID=54161525

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510290999.2A Active CN104946453B (en) 2015-05-25 2015-05-25 A kind of production method of health care medicinal wheat koji

Country Status (1)

Country Link
CN (1) CN104946453B (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105505726A (en) * 2015-12-28 2016-04-20 贵州赤水黔老翁晒醋有限公司 Method for preparing vinegar koji from Chinese herbs and vinegar koji
CN106107905A (en) * 2016-07-04 2016-11-16 王芳 A kind of Fructus Tsaoko local flavor Semen Cajani soy sauce
CN106434261A (en) * 2016-11-16 2017-02-22 吕赵勇 Preparation technology of wheat koji
CN106591085A (en) * 2016-11-16 2017-04-26 吕赵勇 Production process of grain and persimmon vinegar
CN106929276A (en) * 2017-04-13 2017-07-07 施岳峰 A kind of multiplex health care distiller's yeast and preparation method thereof
CN107418822A (en) * 2017-09-14 2017-12-01 立爱生物科技(上海)有限公司 A kind of black polished glutinous rice health liquor and preparation method thereof
CN107904128A (en) * 2017-12-07 2018-04-13 四川大学 A kind of method by adding koji-making Chinese medicine making vinegar
CN108048283A (en) * 2018-01-30 2018-05-18 林州红旗渠酒业有限责任公司 A kind of yeast for improving terpene compound content in yeast aromatic Chinese spirit
CN108277130A (en) * 2018-03-30 2018-07-13 彭阳县虎狮酒业有限公司 The preparation method of distiller's yeast and the production method of yellow rice wine

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101323824A (en) * 2007-06-12 2008-12-17 陕西秦洋长生酒业有限公司 Medical wheat yellow wine yeast and making method thereof
CN101497853A (en) * 2009-02-27 2009-08-05 李家民 Daqu medicament preparation for improving seasoned flavor brewing solid-state white spirit
CN101623038A (en) * 2008-07-08 2010-01-13 刘泳宏 Natural five-color fat-reducing dietic medicinal tea beverage and preparation method
CN102698039A (en) * 2012-06-13 2012-10-03 福州万丰和生物科技有限公司 Pine needle tea beverage
CN103479927A (en) * 2012-06-13 2014-01-01 张淯河 Traditional healthcare medicine for weight reduction and healthcare

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101323824A (en) * 2007-06-12 2008-12-17 陕西秦洋长生酒业有限公司 Medical wheat yellow wine yeast and making method thereof
CN101623038A (en) * 2008-07-08 2010-01-13 刘泳宏 Natural five-color fat-reducing dietic medicinal tea beverage and preparation method
CN101497853A (en) * 2009-02-27 2009-08-05 李家民 Daqu medicament preparation for improving seasoned flavor brewing solid-state white spirit
CN102698039A (en) * 2012-06-13 2012-10-03 福州万丰和生物科技有限公司 Pine needle tea beverage
CN103479927A (en) * 2012-06-13 2014-01-01 张淯河 Traditional healthcare medicine for weight reduction and healthcare

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李大和: "《白酒酿造培训教程》", 30 September 2013 *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105505726A (en) * 2015-12-28 2016-04-20 贵州赤水黔老翁晒醋有限公司 Method for preparing vinegar koji from Chinese herbs and vinegar koji
CN105505726B (en) * 2015-12-28 2018-04-06 贵州赤水黔老翁晒醋有限公司 It is a kind of to make the bent method of vinegar and vinegar song with Chinese herbal medicine
CN106107905A (en) * 2016-07-04 2016-11-16 王芳 A kind of Fructus Tsaoko local flavor Semen Cajani soy sauce
CN106434261A (en) * 2016-11-16 2017-02-22 吕赵勇 Preparation technology of wheat koji
CN106591085A (en) * 2016-11-16 2017-04-26 吕赵勇 Production process of grain and persimmon vinegar
CN106929276A (en) * 2017-04-13 2017-07-07 施岳峰 A kind of multiplex health care distiller's yeast and preparation method thereof
CN107418822A (en) * 2017-09-14 2017-12-01 立爱生物科技(上海)有限公司 A kind of black polished glutinous rice health liquor and preparation method thereof
CN107904128A (en) * 2017-12-07 2018-04-13 四川大学 A kind of method by adding koji-making Chinese medicine making vinegar
CN107904128B (en) * 2017-12-07 2020-11-06 四川大学 Method for brewing vinegar by adding yeast-making Chinese medicinal materials
CN108048283A (en) * 2018-01-30 2018-05-18 林州红旗渠酒业有限责任公司 A kind of yeast for improving terpene compound content in yeast aromatic Chinese spirit
CN108277130A (en) * 2018-03-30 2018-07-13 彭阳县虎狮酒业有限公司 The preparation method of distiller's yeast and the production method of yellow rice wine

Also Published As

Publication number Publication date
CN104946453B (en) 2018-06-08

Similar Documents

Publication Publication Date Title
CN104946453A (en) Preparation and use method of health drug wheat koji
CN101974385B (en) Rice wine yeast and preparation method thereof
CN102344876B (en) Nine-medicine Shengzi red fruit wine and preparation method thereof
CN102380051B (en) Medicinal steamed bread for treating diabetes
CN103740566B (en) Rosa roxbunghii medicinal liquor and preparation method thereof
CN111840363B (en) Natto-assisted hypoglycemic health-care composition and preparation method and application thereof
CN103652160A (en) Dendrobe and jasmine tea and preparation method thereof
CN104906361A (en) Hypolipidemic yellow rice wine and making method thereof
CN105077232A (en) Dendrobium officinale and fructus lycii capsule and preparation method thereof
CN105053955A (en) Blood-glucose-reducing sweetening agent without lingering bitterness
CN110343589A (en) A kind of glutinous rice health preserving wine and its brewage process adding traditional Chinese medicine ingredients
CN104054872A (en) Herbal tea and preparation method thereof
CN106720685A (en) A kind of blue or green money willow instant tea and preparation method thereof
CN104587429B (en) A kind of Rhizoma Zingiberis Recens honey concocts Radix Panacis Quinquefolii preparation and preparation method
CN103404640B (en) Liver and stomach nourishing tea and preparation method thereof
CN104958564A (en) Dendrobium candidum oral liquid and preparing method thereof
CN105901213A (en) Making method of pomegranate tea product
CN104013844A (en) Formula and preparation method of traditional Chinese medicinal preparation capable of promoting hair growth
CN109810824A (en) A kind of dandelion wheat yellow wine yeast and preparation process
CN108865639B (en) A kind of brewing method of pseudo-ginseng monascus vinegar
CN110804518A (en) Preparation method of jasmine flower wine
CN108339060A (en) A kind of hypoglycemic anti-aging stem of noble dendrobium medicinal liquor and preparation method thereof
CN102265956B (en) Ginseng honey tea
CN108902731A (en) A kind of strengthening spleen and nourishing stomach promotes children's intelligence development and the noodles of body growth and preparation method thereof
KR102501508B1 (en) Process for Beverages or Liquors Using Extracts of Herbal Plants

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant