CN104940380A - Composition containing miracle fruit powder and application thereof serving as medicine or health care product - Google Patents
Composition containing miracle fruit powder and application thereof serving as medicine or health care product Download PDFInfo
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- CN104940380A CN104940380A CN201510343188.4A CN201510343188A CN104940380A CN 104940380 A CN104940380 A CN 104940380A CN 201510343188 A CN201510343188 A CN 201510343188A CN 104940380 A CN104940380 A CN 104940380A
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- powder
- synsepalum duleificum
- extract powder
- medicine
- cyclocarya paliurus
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Abstract
The invention relates to the technical field of Chinese medicine compounds and particularly discloses a composition containing miracle fruit powder and application thereof serving as a medicine or a health care product. The composition comprises the following components: miracle fruit freeze-dried powder, royal jelly freeze-dried powder, lychee seed extract powder and cyclocarya paliurus extract powder. The composition has very good effects of decreasing blood sugar and blood fat and protecting liver and can serve as the health care product or the medicine.
Description
Technical field
the present invention relates to Chinese medicine compound technical field, be specifically related to a kind of compositions and the work thereof that contain Synsepalum duleificum powder
For the application of medicine or health product.
Background technology
Synsepalum duleificum, its Classification system is Synsepalum dulcificum Daniell, is typical tropical evergreen shrubs,
Original producton location in West Africa, Ghana, the Congo one is with.The sixties in 20th century, when Premier Zhou Enlai accesses to West Africa,
Republic of Ghana gives premier Zhou using Synsepalum duleificum as state's gift.After this, Synsepalum duleificum starts to cultivate in China.
Synsepalum duleificum is rounded, long 2 centimetres, wide 1.2 centimetres, fruit ruby time ripe, pulp white succulence,
Seed one piece of olive shape, dark brown.In Synsepalum duleificum, sarcocarp contains abundant glucoprotein, vitamin C, citric acid, succinic acid, oxalic acid etc., its magical part is containing a kind of spoiled protease (also known as On Miraculin), eat in Synsepalum duleificum half an hour, then other acid fruits are eaten, can think that these sour water fruits are no longer tart flavour, and become sweet taste, therefore named Synsepalum duleificum.
Current Synsepalum duleificum is mainly sold with fresh fruit or fruit juice form, also Synsepalum duleificum is not developed to medicine or health product.Therefore, Synsepalum duleificum is developed to the larger value that medicine or health product can give play to Synsepalum duleificum, has great importance.
Summary of the invention
Technical problem to be solved by this invention is, in order to overcome the underexploitation of Synsepalum duleificum in medicine and healthcare field in prior art, provides a kind of compositions containing Synsepalum duleificum powder.
Above-mentioned technical problem to be solved by this invention is achieved by the following technical programs:
A compositions containing Synsepalum duleificum powder, comprises following component: Synsepalum duleificum lyophilized powder, Lac regis apis lyophilized powder, Semen Litchi extract powder and Cyclocarya paliurus Iljinskaja powder.
The present invention is in order to develop medicine and the health purpose of Synsepalum duleificum further, and mainly for commonly encountered diseases such as hypertension, hyperlipidemia, hepatic disease, inventor, according to theory of Chinese medical science, gropes allotment through meticulous research, provides above-mentioned Chinese medicine composition.Described compositions has excellent blood sugar lowering, blood fat reducing, hepatoprotective, antialcoholism action, has the effect such as the kidney invigorating or spleen invigorating in addition.
Preferably, described compositions, comprises the component of following weight portion:
Synsepalum duleificum lyophilized powder 1 ~ 3 part; Lac regis apis lyophilized powder 1 ~ 3 part; 1 ~ 3 part, Semen Litchi extract powder; Cyclocarya paliurus Iljinskaja extract powder 1 ~ 3 part.
Further preferably, described compositions, comprises the component of following weight portion:
Synsepalum duleificum lyophilized powder 1 ~ 3 part; Lac regis apis lyophilized powder 1 ~ 3 part; 1 part, Semen Litchi extract powder; Cyclocarya paliurus Iljinskaja extract powder 1 part.
Most preferably, described compositions, comprises the component of following weight portion:
Synsepalum duleificum lyophilized powder 1 part; Lac regis apis lyophilized powder 1 part; 1 part, Semen Litchi extract powder; Cyclocarya paliurus Iljinskaja extract powder 1 part.
Preferably, described Semen Litchi extract powder refers to Semen Litchi water extraction, the powder then obtained after lyophilization.
Preferably, described Cyclocarya paliurus Iljinskaja extract powder refers to Cyclocarya paliurus Iljinskaja water extraction, the powder then obtained after lyophilization.
Preferably, described compositions makes capsule by after described component mixing or be pressed into tablet.
Above-mentioned composition is as the application of the medicine or health product with blood sugar lowering or effect for reducing blood fat.
Above-mentioned composition is as the application of the medicine or health product with the kidney invigorating or function of invigorating spleen.
Above-mentioned composition is as the application of the medicine or health product with hepatoprotective or antialcoholism action.
beneficial effect: (1)the present invention for key component, provides a kind of compositions with medical treatment and health purpose completely newly with Synsepalum duleificum lyophilized powder; (2) compositions of the present invention has the effects such as good blood sugar lowering, blood fat reducing, hepatoprotective, can as health product or drug use.
Detailed description of the invention
Explain the present invention further below in conjunction with specific embodiment, but embodiment does not limit in any form to the present invention.
Embodiment 1
By Synsepalum duleificum lyophilized powder 1kg; Lac regis apis lyophilized powder 1kg; Semen Litchi extract powder 1kg; Cyclocarya paliurus Iljinskaja extract powder 1kg mix homogeneously must contain the compositions of Synsepalum duleificum powder.Again the compositions containing Synsepalum duleificum powder is pressed into through tablet machine the tablet that weight is the every sheet of 0.5g.
Described Semen Litchi extract powder is by after Semen Litchi water heating and refluxing extraction, then the freeze-dried powder will obtained after extracting solution lyophilization.Described Cyclocarya paliurus Iljinskaja extract powder is by after Cyclocarya paliurus Iljinskaja water heating and refluxing extraction, then the freeze-dried powder will obtained after extracting solution lyophilization.
Embodiment 2
By Synsepalum duleificum lyophilized powder 3kg; Lac regis apis lyophilized powder 1kg; Semen Litchi extract powder 1kg; Cyclocarya paliurus Iljinskaja extract powder 1kg mix homogeneously must contain the compositions of Synsepalum duleificum powder.Again the compositions containing Synsepalum duleificum powder is pressed into through tablet machine the tablet that weight is the every sheet of 0.5g.
Described Semen Litchi extract powder is by after Semen Litchi water heating and refluxing extraction, then the freeze-dried powder will obtained after extracting solution lyophilization.Described Cyclocarya paliurus Iljinskaja extract powder is by after Cyclocarya paliurus Iljinskaja water heating and refluxing extraction, then the freeze-dried powder will obtained after extracting solution lyophilization.
Embodiment 3
By Synsepalum duleificum lyophilized powder 3kg; Lac regis apis lyophilized powder 3kg; Semen Litchi extract powder 1kg; Cyclocarya paliurus Iljinskaja extract powder 1kg mix homogeneously must contain the compositions of Synsepalum duleificum powder.Again the compositions containing Synsepalum duleificum powder is incapsulated in shell the capsule making every heavy 0.5g.
Described Semen Litchi extract powder is by after Semen Litchi water heating and refluxing extraction, then the freeze-dried powder will obtained after extracting solution lyophilization.Described Cyclocarya paliurus Iljinskaja extract powder is by after Cyclocarya paliurus Iljinskaja water heating and refluxing extraction, then the freeze-dried powder will obtained after extracting solution lyophilization.
Embodiment 4 blood sugar lowering is tested
Get male and female half and half mice 60, 6 groups are divided at random by body weight, often organize 10, be respectively blank group (10ml/kg water), model control group (10ml/kg water), Synsepalum duleificum lyophilized powder group (only administration Synsepalum duleificum lyophilized powder), compositions group (compositions containing Synsepalum duleificum powder that embodiment 1 ~ 3 prepares) is according to following table administration, in 7 days every day gastric infusion once, gavage volume is 10ml/kg, fasting 5 hours before last administration, last administration is after 2 hours, except blank group, all the other are the equal lumbar injection glucose 2g/kg of group respectively, respectively at after injectable dextrose monohydrate 0.5, 1 and 2 hour, by sacrifice of animal, get blood, blood glucose is surveyed with glucose oxidase method.Result of the test is in table 1.
As can be seen from upper table data, the compositions containing Synsepalum duleificum powder that embodiment 1 ~ 3 prepares has significant hypoglycemic activity, and blood glucose can be made after injected in mice glucose in 1h substantially to recover normal.Its blood sugar decreasing effect is also obviously better than Synsepalum duleificum lyophilized powder.
Embodiment 5 lipid-lowering test
Get rat 60, male and female half and half, be divided into chow diet group (feeding normal diet), high lipid food group, Synsepalum duleificum lyophilized powder group (only administration Synsepalum duleificum lyophilized powder), compositions group (compositions containing Synsepalum duleificum powder that embodiment 1 ~ 3 prepares), often organize is 12, weigh, tail venous blood sampling, measures serum lipid concentrations.The compositions containing Synsepalum duleificum powder that Synsepalum duleificum lyophilized powder group and composition component do not prepare with 2g Synsepalum duleificum lyophilized powder or embodiment 1 ~ 3 mixes with 1kg high lipid food, feeds each group of rat, freely drinks water, weigh 1 time every 10d by group.Successive administration is after 40 days, and put to death animal, abdominal vein gets blood, measures blood fat and hemorheology index.On automatic clinical chemistry analyzer, serum total cholesterol (TC), triglyceride (TG), HDL-C (HDL-C) and low-density lipoprotein cholesterol (LDL-C) content is measured with enzyme process, Precipitation Determination.Lipid-lowering test the results are shown in Table 2.
As can be seen from upper table data, the compositions containing Synsepalum duleificum powder that embodiment 1 ~ 3 prepares has significant effect for reducing blood fat, significantly can reduce the content of T-CHOL (TC), triglyceride (TG), HDL-C (HDL-C) and low-density lipoprotein cholesterol (LDL-C) in the mouse blood of feeding high lipid food; And its effect for reducing blood fat is better than Synsepalum duleificum lyophilized powder.
Embodiment 6 hepatoprotective and experiment of relieving the effect of alcohol
Get Kun Ming mice 60, male and female dual-purpose, body weight 18 ~ 20g, be divided into 5 groups at random, often organize 12, if 4 groups of administration groups, the matched group of (compositions containing Synsepalum duleificum powder that administration group uses embodiment 1 ~ 3 to prepare and Synsepalum duleificum lyophilized powder group) and 1 group of not administration.To wine (53 degree of Chinese liquor) 0.4ml/ only, matched group is to 30min before wine, and gavage feedwater 0.4ml, each administration group is to 30min before wine, and gastric infusion, dosage is 0.1g/kg for each group of gavage.Give 30min clock after drinking, get malonaldehyde (MDA) content in blood measuring blood alcohol concentration, ethanol dehydrogenase (ADH) active regulating liver-QI, the results are shown in Table 3.
Can find out through upper table data, the blood alcohol concentration in administration group mouse blood obviously reduces than the blood alcohol concentration in matched group.Illustrate that the compositions containing Synsepalum duleificum powder of the present invention has good antialcoholism action.ADH on the other hand in administration group mouse blood is active in matched group, and MDA content is also starkly lower than matched group.Illustrate that the compositions containing Synsepalum duleificum powder of the present invention can increase the activity of ADH and reduce the effect of MDA content.Illustrate that the compositions containing Synsepalum duleificum powder of the present invention has good hepatoprotective effect.Show by contrasting with the experimental data of individually dosed Synsepalum duleificum lyophilized powder group, the hepatoprotective effect of the compositions containing Synsepalum duleificum powder of the present invention will due to Synsepalum duleificum lyophilized powder.
Claims (10)
1. the compositions containing Synsepalum duleificum powder, is characterized in that, comprise following component: Synsepalum duleificum lyophilized powder, Lac regis apis lyophilized powder, Semen Litchi extract powder and Cyclocarya paliurus Iljinskaja extract powder.
2. compositions according to claim 1, is characterized in that, comprises the component of following weight portion:
Synsepalum duleificum lyophilized powder 1 ~ 3 part; Lac regis apis lyophilized powder 1 ~ 3 part; 1 ~ 3 part, Semen Litchi extract powder; Cyclocarya paliurus Iljinskaja extract powder 1 ~ 3 part.
3. compositions according to claim 1, is characterized in that, comprises the component of following weight portion:
Synsepalum duleificum lyophilized powder 1 ~ 3 part; Lac regis apis lyophilized powder 1 ~ 3 part; 1 part, Semen Litchi extract powder; Cyclocarya paliurus Iljinskaja extract powder 1 part.
4. compositions according to claim 1, is characterized in that, comprises the component of following weight portion:
Synsepalum duleificum lyophilized powder 1 part; Lac regis apis lyophilized powder 1 part; 1 part, Semen Litchi extract powder; Cyclocarya paliurus Iljinskaja extract powder 1 part.
5. the compositions described in any one of claim 1 ~ 4, is characterized in that, described Semen Litchi extract powder refers to Semen Litchi water extraction, the powder then obtained after lyophilization.
6. the compositions described in any one of claim 1 ~ 4, is characterized in that, described Cyclocarya paliurus Iljinskaja extract powder refers to Cyclocarya paliurus Iljinskaja water extraction, the powder then obtained after lyophilization.
7. the compositions described in any one of claim 1 ~ 4, is characterized in that, makes capsule or is pressed into tablet further by after described component mixing.
8. the compositions described in any one of claim 1 ~ 4 is as the application of the medicine or health product with blood sugar lowering or effect for reducing blood fat.
9. the compositions described in any one of claim 1 ~ 4 is as the application of the medicine or health product with the kidney invigorating or function of invigorating spleen.
10. the compositions described in any one of claim 1 ~ 4 is as the application of the medicine or health product with hepatoprotective or antialcoholism action.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510343188.4A CN104940380A (en) | 2015-06-19 | 2015-06-19 | Composition containing miracle fruit powder and application thereof serving as medicine or health care product |
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| CN201510343188.4A CN104940380A (en) | 2015-06-19 | 2015-06-19 | Composition containing miracle fruit powder and application thereof serving as medicine or health care product |
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| CN104940380A true CN104940380A (en) | 2015-09-30 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105995825A (en) * | 2016-06-24 | 2016-10-12 | 安徽省丰康农业科技有限公司 | Oral royal jelly preparation capable of enhancing immunity and preparation method of oral royal jelly preparation |
| CN106173776A (en) * | 2016-07-15 | 2016-12-07 | 佛山市朗达信息科技有限公司 | A kind of nourishing medicinal granule of enhancing immunity and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104116071A (en) * | 2014-05-29 | 2014-10-29 | 武汉思维特食品有限公司 | Royal jelly, litchi chinensis seed and grifola frondosa microcapsule and preparation method thereof |
-
2015
- 2015-06-19 CN CN201510343188.4A patent/CN104940380A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104116071A (en) * | 2014-05-29 | 2014-10-29 | 武汉思维特食品有限公司 | Royal jelly, litchi chinensis seed and grifola frondosa microcapsule and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 《健康大讲堂》编委会: "《汉方青草药养生圣经》", 31 January 2013 * |
| 文燕等，: "《神奇的青钱柳与糖尿病》", 28 February 2015 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105995825A (en) * | 2016-06-24 | 2016-10-12 | 安徽省丰康农业科技有限公司 | Oral royal jelly preparation capable of enhancing immunity and preparation method of oral royal jelly preparation |
| CN106173776A (en) * | 2016-07-15 | 2016-12-07 | 佛山市朗达信息科技有限公司 | A kind of nourishing medicinal granule of enhancing immunity and preparation method thereof |
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Application publication date: 20150930 |