CN104940047B - A kind of cosmetic composition of replenishing water and preserving moisture and preparation method thereof - Google Patents
A kind of cosmetic composition of replenishing water and preserving moisture and preparation method thereof Download PDFInfo
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- CN104940047B CN104940047B CN201510359139.XA CN201510359139A CN104940047B CN 104940047 B CN104940047 B CN 104940047B CN 201510359139 A CN201510359139 A CN 201510359139A CN 104940047 B CN104940047 B CN 104940047B
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 57
- 239000002537 cosmetic Substances 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 102000010637 Aquaporins Human genes 0.000 claims abstract description 8
- 108010063290 Aquaporins Proteins 0.000 claims abstract description 8
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 8
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 7
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 7
- 239000012071 phase Substances 0.000 claims description 9
- 239000002671 adjuvant Substances 0.000 claims description 8
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims description 4
- 239000008346 aqueous phase Substances 0.000 claims description 3
- 239000003755 preservative agent Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 2
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 2
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 2
- 150000001413 amino acids Chemical class 0.000 claims description 2
- 229960003237 betaine Drugs 0.000 claims description 2
- 239000004202 carbamide Substances 0.000 claims description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- 229960003080 taurine Drugs 0.000 claims description 2
- 229940074410 trehalose Drugs 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 16
- 239000000047 product Substances 0.000 abstract description 15
- 230000003020 moisturizing effect Effects 0.000 abstract description 10
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 abstract description 6
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 abstract description 5
- 239000013589 supplement Substances 0.000 abstract description 5
- 230000004888 barrier function Effects 0.000 abstract description 4
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 2
- 230000009471 action Effects 0.000 abstract description 2
- 208000026935 allergic disease Diseases 0.000 abstract description 2
- 230000007815 allergy Effects 0.000 abstract description 2
- 230000000295 complement effect Effects 0.000 abstract description 2
- 230000005945 translocation Effects 0.000 abstract description 2
- 230000000052 comparative effect Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 239000010410 layer Substances 0.000 description 4
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 3
- 108091006146 Channels Proteins 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000009847 Cucumis melo var cantalupensis Nutrition 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 239000000232 Lipid Bilayer Substances 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000000476 body water Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000013098 chemical test method Methods 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 238000013031 physical testing Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention discloses a kind of cosmetic composition of replenishing water and preserving moisture and preparation method thereof, said composition uses the replenishing water and preserving moisture component of following mass percent：Macromolecular Sodium Hyaluronate 0.02~0.10%, Alps glacial water 1.00~4.00%, antierythrite 1.00~4.00%, aquaporin 1.00~3.00%.Diaphragm is formed with macromolecular Sodium Hyaluronate in the present invention, plays the effect of barrier action；After Alps glacial water and antierythrite reach target area, continuously keep the skin wet；Aquaporin plays translocation, improves moisturizing effect；Three steps form front and rear complementation, the effect to supplement and complement each other, more effectively play replenishing water and preserving moisture effect.Phenomena such as product of the present invention will not produce allergy to user, stimulate, it is safe to use；This product has significant effect on the effect of replenishing water and preserving moisture.
Description
【Technical field】
The present invention relates to a kind of cosmetic composition of replenishing water and preserving moisture and preparation method thereof, belong to cosmetic technical field.
【Background technology】
Replenishing water and preserving moisture is exactly effectively to be kept the skin wet for skin, and it is to act directly on skin that it, which acts on embodiment, or from week
Collarette border absorbs moisture, and moist effect is supported to make skin reach water.
The generation of scaly dry skin：People obtains the various required metabolism reactions of oxygen progress human body by breathing, at this
During can consume moisture in human body；Lack moisture in air, trigger the loss of skin moisture；This two can be by drinking water
To supplement.With the hyperplasia at age, the ratio that cell carries moisture is fewer and fewer, and it is in drying regime to cause skin, and this need to pass through
Daily skin nursing keeps the skin wet.
Human body skin top layer (cuticula) moisture accounts for 15-30%, and it is in dry crude, skin that the loss of moisture, which can make skin,
Skin is dull, more spots, aging are accelerated；In addition to drinking water, another approach is supplemented in skin the supplement of body water by moisturizer
Moisture.
Increasing research shows that diaphragm is the essential step for reducing water loss；Because external condition makes skin water
Divide volatilization to be lost in, cause moisture to reduce, therefore the approach that can efficiently reduce moisture evaporation is effective external diaphragm
Layer.It is effectively protected film layer：1st, grease type, 2, the high molecular polymer of network structure.
【The content of the invention】
The invention aims to overcome the spontaneous effect weak point of existing cosmetics moisturizing composition, there is provided a kind of quick,
Efficient replenishing water and preserving moisture cosmetic composition.
It is a further object of the present invention to provide a kind of preparation method of above-mentioned composition.
The present invention to achieve the above object, using following technical scheme：
A kind of cosmetic composition of replenishing water and preserving moisture, it is characterised in that using the replenishing water and preserving moisture group of following mass percent
Point：
The molecular weight of macromolecular Sodium Hyaluronate in the present invention is 1800000~2200000.Aquaporin in the present invention
Albumen, consisting of：Water, urea, yeast amino acid class, trehalose, taurine, glycine betaine, opening positive chemical science and technology by Guangzhou has
Limit company produces, model：AC Dermal Moisture Complex.
The present invention is from macromolecular Sodium Hyaluronate as first of barrier；Macromolecular Sodium Hyaluronate (molecular weight ranges
000) 1800 000~2200 can form one layer of ventilative film in skin surface, effectively block the loss of moisture, can be
Automatically adjusted in varying environment, maintain moisture of skin to keep moistening, clearly for skin in 25-30% all the time.
The key of moisturizing is：Moisturizing source -- Alps glacial water.Alps is European maximum mountainous villas
Center.Each drop glacial water breeds hundreds of millions of years on stratum, Minerals And Rocks filtering in more than 50 years is undergone, with fixed flow velocity and constant temperature
Degree is constantly gushed out, and mineral content ratio is especially suitable for human body requirements, is the water that a suitable skin is drunk；To human metabolism,
Cell procreation plays the role of positive, can open skin water circulation channel, microelement-supplementing, allow skin enjoying pure pure and fresh ring
While border, carry back and obtain water replenishment by skin.
Another moisturizing source -- antierythrite (new natural moisture preserving agent).It is naturally occurring in marine alga, mushroom, muskmelon, grape
In fermented foodstuff.
The effective step of replenishing water and preserving moisture：Pipeline.Effective pipeline, moisturizing material can be made preferably to penetrate cuticula
Barrier, go directly target area；All cells containing unique across memebrane protein, referred to as aquaporin, they
Shuttle transport moisture between the lipid bilayer for being difficult to permeate.
The present composition is compounded by water phase components and adjuvant component with replenishing water and preserving moisture component.
Water phase components in the present invention are made up of following mass percent component：
Adjuvant component in the present invention is one or two kinds of in essence and preservative.
The composition of each component in each phase is that the percentage using cosmetic composition total amount of the present invention as radix contains above
Amount, water consumption surplus therein are the percent of totals for instigating replenishing water and preserving moisture component, water phase components and adjuvant component for absolutely.
A kind of preparation method of the cosmetic composition of above-mentioned replenishing water and preserving moisture, it is characterised in that comprise the following steps：
A, water phase components are added in aqueous phase pot, is heated to 83 ± 2 DEG C, is incubated at 80~85 DEG C, stirring and dissolving is uniform；
When b, being cooled to 30~45 DEG C, replenishing water and preserving moisture component and adjuvant component are added, is stirred.
The present invention has the advantage that relative to prior art：
The macromolecular Sodium Hyaluronate used in the present invention, it is complemented at the same of skin effectively absorbing outside moisture
When, the protective layer of network structure can be formed, the volatilization of moisture of skin is effectively blocked, there is double effect；Alps glacial water,
From natural glacial water, skin water circulation channel can be opened, microelement-supplementing, allows skin enjoying pure pure and fresh environment
While, carry back and obtain water replenishment by skin；Antierythrite, natural moisturizing material, gentle safety；Aquaporin egg
In vain, it can effectively carry moisturizing material and act on moisturizing region, efficiently play the function of moisturizing material.
This combination mechanism is that macromolecular Sodium Hyaluronate forms diaphragm, plays the effect of barrier action；Alps ice
After Chuan Shui and antierythrite reach target area, continuously keep the skin wet；Aquaporin plays translocation, improves and mends
Water effect；Three steps form front and rear complementation, the effect to supplement and complement each other, more effectively play replenishing water and preserving moisture effect.
Phenomena such as product of the present invention will not produce allergy to user, stimulate, it is safe to use；This product is in replenishing water and preserving moisture
There is significant effect in effect.
【Embodiment】
With reference to specific embodiment, the present invention will be further described：
Embodiment 1-3 and comparative example 1-3 mass percent proportioning is as shown in table 1：
Table 1：
Embodiment 1-3 is identical with comparative example 1-3 preparation method, comprises the following steps：
A, water phase components are added in aqueous phase pot, is heated to 83 ± 2 DEG C, is incubated at 80~85 DEG C, stirring and dissolving is uniform；
When b, being cooled to 30~45 DEG C, replenishing water and preserving moisture component and adjuvant component are added, is stirred.
Embodiment 1-3 and comparative example 1-3 replenishing water and preserving moisture cosmetic composition does physical and chemical testing, and its test is as follows：
1. outward appearance：Clear viscous liquids
2.pH values：5.0-7.0
3. heat-resistant stability investigates (48 DEG C × 24h):It is qualified
4. cold-resistant study on the stability (- 15 DEG C × 24h):It is qualified
The effect of in order to prove this product, tests below is carried out：
First, security test：
200 voluntary testers are chosen, to do control test on the inside of left and right arm, apply present invention production every time on the inside of left hand
Product 0.5g, right hand inner side apply blank base-material 0.5g, twice daily, and record the dermoreaction phenomenon after 24h, 72h.
As a result show：After applying product 24h, 72h of the present invention, have no rubefaction or the allergic phenomenas such as erythema, explanation occur
Product replenishing water and preserving moisture modularization cosmetic of the present invention is safe, without any bad phenomenon.
2nd, efficacy test：
Experimental method：
Group one (100 people) the common cosmetics of in the market, 3 times a day, it is used continuously 1 month；
Group two (100 people) product of the embodiment of the present invention 1,3 times a day, it is used continuously 1 month；
Group three (100 people) product of the embodiment of the present invention 2,3 times a day, it is used continuously 1 month；
Group four (100 people) product of the embodiment of the present invention 3,3 times a day, it is used continuously 1 month；
Group five (100 people) product of comparative example 1 of the present invention, 3 times a day, it is used continuously 1 month；
Group six (100 people) product of comparative example 2 of the present invention, 3 times a day, it is used continuously 1 month；
Group seven (100 people) product of comparative example 3 of the present invention, 3 times a day, it is used continuously 1 month.
Experimental result is as shown in table 2：
Table 2：
| Project | The obvious neatly of skin | Skin slightly improves | Skin is without improvement |
| Group one | 0 | 5 | 95 |
| Group two | 90 | 10 | 0 |
| Group three | 95 | 5 | 0 |
| Group four | 97 | 3 | 0 |
| Group five | 75 | 25 | 0 |
| Group six | 72 | 28 | 0 |
| Group seven | 77 | 23 | 0 |
As can be seen from Table 2, product of the present invention has good replenishing water and preserving moisture ability, can effectively supplement moisture needed for skin；
The significant effect compared with general cosmetics, the present invention is by Alps and antierythrite, aquaporin compounding than wherein
The replenishing water and preserving moisture effect of any two kinds of compoundings is good.
Claims (5)
1. a kind of cosmetic composition of replenishing water and preserving moisture, it is characterised in that using the replenishing water and preserving moisture component of following mass percent：
The molecular weight of the macromolecular Sodium Hyaluronate is 1800000~2200000；
Described aquaporin, consisting of：Water, urea, yeast amino acid class, trehalose, taurine, glycine betaine.
2. the cosmetic composition of a kind of replenishing water and preserving moisture according to claim 1, it is characterised in that the composition is by water
Phase component and adjuvant component compound with replenishing water and preserving moisture component.
A kind of 3. cosmetic composition of replenishing water and preserving moisture according to claim 2, it is characterised in that described water phase components
It is made up of following mass percent component：
A kind of 4. cosmetic composition of replenishing water and preserving moisture according to claim 2, it is characterised in that described adjuvant component
For one or two in essence and preservative.
A kind of 5. preparation method of the cosmetic composition of replenishing water and preserving moisture any one of claim 2-4, it is characterised in that
Comprise the following steps：
A, water phase components are added in aqueous phase pot, is heated to 83 ± 2 DEG C, is incubated at 80~85 DEG C, stirring and dissolving is uniform；
When b, being cooled to 30~45 DEG C, replenishing water and preserving moisture component and adjuvant component are added, is stirred.
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105342943B (en) * | 2015-12-16 | 2018-12-25 | 广州市中通生化制品有限公司 | A kind of condensation and preparation method thereof containing Chinese herbal medicine extract |
| CN107375049A (en) * | 2017-07-27 | 2017-11-24 | 朱思文 | One primary yeast repairs essence lotion |
| CN108371645A (en) * | 2018-03-30 | 2018-08-07 | 广州科盈化妆品有限公司 | A kind of moisture retention water and preparation method thereof containing glacial water |
| CN108324641A (en) * | 2018-03-30 | 2018-07-27 | 广东巴松那生物科技有限公司 | A kind of composition and preparation method thereof for hormone surface skin reparation containing cryptomeria bud extract |
| CN108670893B (en) * | 2018-07-27 | 2019-05-28 | 乳源南岭好山好水化妆品有限公司 | Amino acid cleansing cream composition and preparation method thereof |
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|---|---|---|---|---|
| CN103315934A (en) * | 2013-06-21 | 2013-09-25 | 深圳市金因生物技术有限公司 | Composition for promoting opening of skin aquaporin and preparation method thereof |
| CN104042464A (en) * | 2014-05-31 | 2014-09-17 | 青岛博泓海洋生物技术有限公司 | Whitening skin-care essence liquid |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP3513873B2 (en) * | 1999-01-26 | 2004-03-31 | 株式会社コーセー | External preparation for skin |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103315934A (en) * | 2013-06-21 | 2013-09-25 | 深圳市金因生物技术有限公司 | Composition for promoting opening of skin aquaporin and preparation method thereof |
| CN104042464A (en) * | 2014-05-31 | 2014-09-17 | 青岛博泓海洋生物技术有限公司 | Whitening skin-care essence liquid |
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| 水动能因子——水通道蛋白;佚名;《http://www.cosdna.com/chs/supplier/水通道蛋白.html》;20150202;第1页 * |
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Denomination of invention: The invention relates to a moisturizing cosmetic composition and a preparation method thereof Effective date of registration: 20210927 Granted publication date: 20171201 Pledgee: Shanghai Pudong Development Bank Limited by Share Ltd. Guangzhou branch Pledgor: GUANGZHOU BESE CLEAN COSMETICS MANUFACTURER Co.,Ltd. Registration number: Y2021440000306 |
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| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
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Date of cancellation: 20220930 Granted publication date: 20171201 Pledgee: Shanghai Pudong Development Bank Limited by Share Ltd. Guangzhou branch Pledgor: GUANGZHOU BESE CLEAN COSMETICS MANUFACTURER Co.,Ltd. Registration number: Y2021440000306 |
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| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A cosmetic composition for moisturizing and moisturizing and its preparation method Effective date of registration: 20221012 Granted publication date: 20171201 Pledgee: Shanghai Pudong Development Bank Limited by Share Ltd. Guangzhou branch Pledgor: GUANGZHOU BESE CLEAN COSMETICS MANUFACTURER Co.,Ltd. Registration number: Y2022440000267 |