CN104922574A - Xin'an capsule and preparation method thereof - Google Patents

Abstract

The invention discloses a xin'an capsule and a preparation method thereof. The xin'an capsule mainly comprises the following raw materials: 1500-1800 parts of hawthorn leaves, absolute ethyl alcohol which accounts for 50%-70% of the total weight of the hawthorn leaves, and the like.

Description

A kind of Xinan Capsule and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Xinan Capsule and preparation method thereof.

Background technology

Research auxiliary function for lowering blood pressure food object is not be to reduce patients' blood merely, and emphasis is to improve hypertension symptom, promotes the recovery of the heart, brain, kidney, blood vessel pathological change.Modern medicine study proves, doctor trained in Western medicine depressor and traditional Chinese medical science depressor respectively have its pluses and minuses.Western medicine the unresolved pathological factor causing blood pressure to raise, the rising once drug withdrawal blood pressure will rebound very soon, makes patient take medicine all the life; Though the antihypertensive effect of Chinese medicine is not as Western medicine, by its adjustment to internal organs function, improve the pathological factor that causes blood pressure to raise and reach the effect of control blood pressure rising.And the traditional Chinese medical science thinks that Diet cures more than the doctors, the ideal chose of the hyperpietic especially of the medicine with medicine-food two-purpose.Research shows, antihypertensive function food functional component mainly contains flavone (rutin etc.), saponin, unsaturated fatty acid, crude polysaccharides, oligosaccharides, vitamin, potassium magnesium selenium and other trace elements.

At present, market has the health food of kind more than 60 " aided blood pressure-lowering " function, product mostly and the function such as auxiliary antilipemic, improving water flood, antioxidation, auxiliary hyperglycemic arrange in pairs or groups, most aided blood pressure-lowering material also has the function of blood fat reducing.Dosage form, be that the capsule of raw material, tea-drinking, extract electuary are the most common with Chinese herbal medicine.

The development of Chinese medicine, needs innovation, particularly modern society, dietary structure, operating pressure, and living environment contacts more chemical material, the body constitution of people and morbid state, there is change in various degree, the formula of Chinese medicine prescription and Chinese patent medicine, be not exclusively applicable to modern.Indiscriminately imitate ancient prescription simply, indiscriminately imitate Chinese medicine theory, research and production medicine, be not exclusively suitable for the New Times.So according to the modern symptom of modern, studied raising, perfect, be only the development of Chinese medicine.The such as prescription drug of Chinese medicine tonification class, in ancient times, the means of production, ideology are relatively backward, and living standard is quite poor, people's major part is in dreadful conditions of life, and body constitution is weak, and the life-span is short, take tonification medicine, may be very effective, side effect is also obvious not; And modern, living condition improves, and body constitution is also different, indiscriminately imitates traditional tonic to eat, a lot of with regard to problem, connects common mild medicine, eat just got angry less than several days, scorching, produce serious side effects, cannot adhere to eating at all.Like this to treatment and the medical production itself of patient, it is all a kind of waste.Through finding the most of formulating of tradition, the space can improving raising is very big, produces the curative effect of modern and healthy if do not improve to improve according to former side, and the newfound function of Chinese medicine, the scientific utilization of chemical composition, and the development to motherland's medical science are all disadvantageous.The problem that the present invention relates to also is the same, and the Chinese patent medicine that tradition is similar not exclusively adapts to the pathology needs of modern, so improve and research similar drug, significant.

So the problem of several aspects utilizing the active ingredient of Folium Crataegi extract and treatment heart disease to consider, carries out science component, a good medicine will be succeeded in developing.

Summary of the invention

For above-mentioned deficiency of the prior art, the object of the invention is to provide a kind of Xinan Capsule and preparation method thereof

A kind of Xinan Capsule, described capsule raw material weight component proportion is as follows: Folium Crataegi 1500-1800 part, and dehydrated alcohol is the 50%-70% of haw heaf total weight, silkworm compound amino acid, 30 ~ 50 parts, Radix Achyranthis Bidentatae: 40 ~ 80 parts, Radix Glycyrrhizae Preparata: 50 ~ 80 parts, Rhizoma Curculiginis: 40 ~ 90 parts, Herba Cistanches: 30 ~ 100 parts, Rhizoma Panacis Japonici: 40 ~ 70 parts, Fructus Schisandrae Chinensis: 9 ~ 15 parts, Cornu Cervi Pantotrichum: 10 ~ 20 parts, Pyritum: 9 ~ 24 parts, Fructus Hordei Germinatus 100-150 part, Flos Chrysanthemi Indici 50-100 part, Fructus Gardeniae 100-150 part, Semen Cassiae 150-200 part, Radix Scutellariae 120-160 part, Fructus Lycii 80-120 part, Folium Kaki 140-180 part, Radix Puerariae 150-200 part, Spica Prunellae 50-100 part, Ganoderma 100-150 part, Radix Notoginseng 90-130 part, Radix Bupleuri 100-150 part, Folium Apocyni Veneti 140-180 part, Stigma Maydis 50-100 part, Radix Platycodonis 120-160 part, Folium Nelumbinis 100-150 part, Radix Polygoni Multiflori 100-200 part, Fructus Alpiniae Oxyphyllae 100-200 part, Cortex Moutan 100-200 part, Semen Nelumbinis 100-200 part.

Preferably, described capsule raw material weight component proportion is as follows: Folium Crataegi 1500 parts, and dehydrated alcohol is 50% of haw heaf total weight, silkworm compound amino acid, 30 parts, Radix Achyranthis Bidentatae: 40 parts; Radix Glycyrrhizae Preparata: 50 parts; Rhizoma Curculiginis: 40 parts; Herba Cistanches: 30 parts; Rhizoma Panacis Japonici: 40 parts; Fructus Schisandrae Chinensis: 9 parts; Cornu Cervi Pantotrichum: 10 parts; Pyritum: 9 parts; Fructus Hordei Germinatus 100 parts, Flos Chrysanthemi Indici 50 parts, Fructus Gardeniae 100 parts, Semen Cassiae 150 parts, Radix Scutellariae 120 parts, Fructus Lycii 80 parts, Folium Kaki 140 parts, Radix Puerariae 150 parts, Spica Prunellae 50 parts, Ganoderma 100 parts, Radix Notoginseng 90 parts, Radix Bupleuri 100 parts, Folium Apocyni Veneti 140 parts, Stigma Maydis 50 parts, Radix Platycodonis 120 parts, 100 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 100 parts, Fructus Alpiniae Oxyphyllae 100 parts, Cortex Moutan 100 parts, 100 parts, Semen Nelumbinis.

Preferably, described capsule raw material weight component proportion is as follows: Folium Crataegi 1800 parts, and dehydrated alcohol is 70% of haw heaf total weight, silkworm compound amino acid 50 parts, Radix Achyranthis Bidentatae 80 parts; Radix Glycyrrhizae Preparata 80 parts; Rhizoma Curculiginis 90 parts; Herba Cistanches 100 parts; Rhizoma Panacis Japonici 70 parts; Fructus Schisandrae Chinensis 15 parts; 20 parts, Cornu Cervi Pantotrichum; Pyritum 24 parts; Fructus Hordei Germinatus 150 parts, Flos Chrysanthemi Indici 100 parts, Fructus Gardeniae 150 parts, Semen Cassiae 200 parts, Radix Scutellariae 160 parts, Fructus Lycii 120 parts, Folium Kaki 180 parts, Radix Puerariae 200 parts, Spica Prunellae 100 parts, Ganoderma 150 parts, Radix Notoginseng 130 parts, Radix Bupleuri 150 parts, Folium Apocyni Veneti 180 parts, Stigma Maydis 100 parts, Radix Platycodonis 160 parts, 150 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 200 parts, Fructus Alpiniae Oxyphyllae 200 parts, Cortex Moutan 200 parts, 200 parts, Semen Nelumbinis.

Preferably, described capsule raw material weight component proportion is as follows: Folium Crataegi 1500 parts, and dehydrated alcohol is 70% of haw heaf total weight, silkworm compound amino acid 45 parts, Radix Achyranthis Bidentatae 56 parts; Radix Glycyrrhizae Preparata 65 parts; Rhizoma Curculiginis 70 parts; Herba Cistanches 45 parts; Rhizoma Panacis Japonici 55 parts; Fructus Schisandrae Chinensis 13 parts; 15 parts, Cornu Cervi Pantotrichum; Pyritum 20 parts; Fructus Hordei Germinatus 130 parts, Flos Chrysanthemi Indici 58 parts, Fructus Gardeniae 118 parts, Semen Cassiae 168 parts, Radix Scutellariae 156 parts, Fructus Lycii 88 parts, Folium Kaki 168 parts, Radix Puerariae 188 parts, Spica Prunellae 88 parts, Ganoderma 116 parts, Radix Notoginseng 120 parts, Radix Bupleuri 130 parts, Folium Apocyni Veneti 150 parts, Stigma Maydis 80 parts, Radix Platycodonis 158 parts, 120 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 180 parts, Fructus Alpiniae Oxyphyllae 180 parts, Cortex Moutan 150 parts, 160 parts, Semen Nelumbinis.

The preparation method of described Xinan Capsule, the step of described method comprises:

According to raw material components proportioning raw materials weighing, be pulverized and mixed by solid material evenly, add dehydrated alcohol, reflux, extract, filter, reclaim ethanol, be condensed into cream, ovendry power is broken into fine powder, measures content, makes granule, dry, encapsulated, to obtain final product.

beneficial effect:

expansion coronary vasodilator, improves blood supply of cardiac muscle amount, reduces blood fat.Be used for the treatment of coronary heart disease, angina pectoris, chest distress and palpitation symptoms, hypertension etc.

Detailed description of the invention

embodiment 1

Described capsule raw material weight component proportion is as follows: Folium Crataegi 1500 parts, and dehydrated alcohol is 50% of haw heaf total weight, silkworm compound amino acid, 30 parts, Radix Achyranthis Bidentatae: 40 parts; Radix Glycyrrhizae Preparata: 50 parts; Rhizoma Curculiginis: 40 parts; Herba Cistanches: 30 parts; Rhizoma Panacis Japonici: 40 parts; Fructus Schisandrae Chinensis: 9 parts; Cornu Cervi Pantotrichum: 10 parts; Pyritum: 9 parts; Fructus Hordei Germinatus 100 parts, Flos Chrysanthemi Indici 50 parts, Fructus Gardeniae 100 parts, Semen Cassiae 150 parts, Radix Scutellariae 120 parts, Fructus Lycii 80 parts, Folium Kaki 140 parts, Radix Puerariae 150 parts, Spica Prunellae 50 parts, Ganoderma 100 parts, Radix Notoginseng 90 parts, Radix Bupleuri 100 parts, Folium Apocyni Veneti 140 parts, Stigma Maydis 50 parts, Radix Platycodonis 120 parts, 100 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 100 parts, Fructus Alpiniae Oxyphyllae 100 parts, Cortex Moutan 100 parts, 100 parts, Semen Nelumbinis.

embodiment 2

Described capsule raw material weight component proportion is as follows: Folium Crataegi 1800 parts, and dehydrated alcohol is 70% of haw heaf total weight, silkworm compound amino acid 50 parts, Radix Achyranthis Bidentatae 80 parts; Radix Glycyrrhizae Preparata 80 parts; Rhizoma Curculiginis 90 parts; Herba Cistanches 100 parts; Rhizoma Panacis Japonici 70 parts; Fructus Schisandrae Chinensis 15 parts; 20 parts, Cornu Cervi Pantotrichum; Pyritum 24 parts; Fructus Hordei Germinatus 150 parts, Flos Chrysanthemi Indici 100 parts, Fructus Gardeniae 150 parts, Semen Cassiae 200 parts, Radix Scutellariae 160 parts, Fructus Lycii 120 parts, Folium Kaki 180 parts, Radix Puerariae 200 parts, Spica Prunellae 100 parts, Ganoderma 150 parts, Radix Notoginseng 130 parts, Radix Bupleuri 150 parts, Folium Apocyni Veneti 180 parts, Stigma Maydis 100 parts, Radix Platycodonis 160 parts, 150 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 200 parts, Fructus Alpiniae Oxyphyllae 200 parts, Cortex Moutan 200 parts, 200 parts, Semen Nelumbinis.

embodiment 3

Described capsule raw material weight component proportion is as follows: Folium Crataegi 1500 parts, and dehydrated alcohol is 70% of haw heaf total weight, silkworm compound amino acid 45 parts, Radix Achyranthis Bidentatae 56 parts; Radix Glycyrrhizae Preparata 65 parts; Rhizoma Curculiginis 70 parts; Herba Cistanches 45 parts; Rhizoma Panacis Japonici 55 parts; Fructus Schisandrae Chinensis 13 parts; 15 parts, Cornu Cervi Pantotrichum; Pyritum 20 parts; Fructus Hordei Germinatus 130 parts, Flos Chrysanthemi Indici 58 parts, Fructus Gardeniae 118 parts, Semen Cassiae 168 parts, Radix Scutellariae 156 parts, Fructus Lycii 88 parts, Folium Kaki 168 parts, Radix Puerariae 188 parts, Spica Prunellae 88 parts, Ganoderma 116 parts, Radix Notoginseng 120 parts, Radix Bupleuri 130 parts, Folium Apocyni Veneti 150 parts, Stigma Maydis 80 parts, Radix Platycodonis 158 parts, 120 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 180 parts, Fructus Alpiniae Oxyphyllae 180 parts, Cortex Moutan 150 parts, 160 parts, Semen Nelumbinis.

Last it is noted that obviously, above-described embodiment is only for example of the present invention is clearly described, and the restriction not to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without the need to also giving all embodiments.And thus the apparent change of amplifying out or variation be still among protection scope of the present invention.

Claims (5)

1. an Xinan Capsule, is characterized in that, described capsule raw material weight component proportion is as follows: Folium Crataegi 1500-1800 part, and dehydrated alcohol is the 50%-70% of haw heaf total weight, silkworm compound amino acid, 30 ~ 50 parts, Radix Achyranthis Bidentatae: 40 ~ 80 parts, Radix Glycyrrhizae Preparata: 50 ~ 80 parts, Rhizoma Curculiginis: 40 ~ 90 parts, Herba Cistanches: 30 ~ 100 parts, Rhizoma Panacis Japonici: 40 ~ 70 parts, Fructus Schisandrae Chinensis: 9 ~ 15 parts, Cornu Cervi Pantotrichum: 10 ~ 20 parts, Pyritum: 9 ~ 24 parts, Fructus Hordei Germinatus 100-150 part, Flos Chrysanthemi Indici 50-100 part, Fructus Gardeniae 100-150 part, Semen Cassiae 150-200 part, Radix Scutellariae 120-160 part, Fructus Lycii 80-120 part, Folium Kaki 140-180 part, Radix Puerariae 150-200 part, Spica Prunellae 50-100 part, Ganoderma 100-150 part, Radix Notoginseng 90-130 part, Radix Bupleuri 100-150 part, Folium Apocyni Veneti 140-180 part, Stigma Maydis 50-100 part, Radix Platycodonis 120-160 part, Folium Nelumbinis 100-150 part, Radix Polygoni Multiflori 100-200 part, Fructus Alpiniae Oxyphyllae 100-200 part, Cortex Moutan 100-200 part, Semen Nelumbinis 100-200 part.

2. Xinan Capsule according to claim 1, is characterized in that, described capsule raw material weight component proportion is as follows: Folium Crataegi 1500 parts, and dehydrated alcohol is 50% of haw heaf total weight, silkworm compound amino acid, 30 parts, Radix Achyranthis Bidentatae: 40 parts; Radix Glycyrrhizae Preparata: 50 parts; Rhizoma Curculiginis: 40 parts; Herba Cistanches: 30 parts; Rhizoma Panacis Japonici: 40 parts; Fructus Schisandrae Chinensis: 9 parts; Cornu Cervi Pantotrichum: 10 parts; Pyritum: 9 parts; Fructus Hordei Germinatus 100 parts, Flos Chrysanthemi Indici 50 parts, Fructus Gardeniae 100 parts, Semen Cassiae 150 parts, Radix Scutellariae 120 parts, Fructus Lycii 80 parts, Folium Kaki 140 parts, Radix Puerariae 150 parts, Spica Prunellae 50 parts, Ganoderma 100 parts, Radix Notoginseng 90 parts, Radix Bupleuri 100 parts, Folium Apocyni Veneti 140 parts, Stigma Maydis 50 parts, Radix Platycodonis 120 parts, 100 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 100 parts, Fructus Alpiniae Oxyphyllae 100 parts, Cortex Moutan 100 parts, 100 parts, Semen Nelumbinis.

3. Xinan Capsule according to claim 1, is characterized in that, described capsule raw material weight component proportion is as follows: Folium Crataegi 1800 parts, and dehydrated alcohol is 70% of haw heaf total weight, silkworm compound amino acid 50 parts, Radix Achyranthis Bidentatae 80 parts; Radix Glycyrrhizae Preparata 80 parts; Rhizoma Curculiginis 90 parts; Herba Cistanches 100 parts; Rhizoma Panacis Japonici 70 parts; Fructus Schisandrae Chinensis 15 parts; 20 parts, Cornu Cervi Pantotrichum; Pyritum 24 parts; Fructus Hordei Germinatus 150 parts, Flos Chrysanthemi Indici 100 parts, Fructus Gardeniae 150 parts, Semen Cassiae 200 parts, Radix Scutellariae 160 parts, Fructus Lycii 120 parts, Folium Kaki 180 parts, Radix Puerariae 200 parts, Spica Prunellae 100 parts, Ganoderma 150 parts, Radix Notoginseng 130 parts, Radix Bupleuri 150 parts, Folium Apocyni Veneti 180 parts, Stigma Maydis 100 parts, Radix Platycodonis 160 parts, 150 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 200 parts, Fructus Alpiniae Oxyphyllae 200 parts, Cortex Moutan 200 parts, 200 parts, Semen Nelumbinis.

4. Xinan Capsule according to claim 1, is characterized in that, described capsule raw material weight component proportion is as follows: Folium Crataegi 1500 parts, and dehydrated alcohol is 70% of haw heaf total weight, silkworm compound amino acid 45 parts, Radix Achyranthis Bidentatae 56 parts; Radix Glycyrrhizae Preparata 65 parts; Rhizoma Curculiginis 70 parts; Herba Cistanches 45 parts; Rhizoma Panacis Japonici 55 parts; Fructus Schisandrae Chinensis 13 parts; 15 parts, Cornu Cervi Pantotrichum; Pyritum 20 parts; Fructus Hordei Germinatus 130 parts, Flos Chrysanthemi Indici 58 parts, Fructus Gardeniae 118 parts, Semen Cassiae 168 parts, Radix Scutellariae 156 parts, Fructus Lycii 88 parts, Folium Kaki 168 parts, Radix Puerariae 188 parts, Spica Prunellae 88 parts, Ganoderma 116 parts, Radix Notoginseng 120 parts, Radix Bupleuri 130 parts, Folium Apocyni Veneti 150 parts, Stigma Maydis 80 parts, Radix Platycodonis 158 parts, 120 parts, Folium Nelumbinis, the Radix Polygoni Multiflori 180 parts, Fructus Alpiniae Oxyphyllae 180 parts, Cortex Moutan 150 parts, 160 parts, Semen Nelumbinis.

5. the preparation method of Xinan Capsule described in claim 1-4 any one, is characterized in that, the step of described method comprises:

According to raw material components proportioning raw materials weighing, be pulverized and mixed by solid material evenly, add dehydrated alcohol, reflux, extract, filter, reclaim ethanol, be condensed into cream, ovendry power is broken into fine powder, measures content, makes granule, dry, encapsulated, to obtain final product.