CN104922468A - Heat-from-throat-clearing and yin-nourishing composition and preparation method thereof - Google Patents
Heat-from-throat-clearing and yin-nourishing composition and preparation method thereof Download PDFInfo
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- CN104922468A CN104922468A CN201510278074.6A CN201510278074A CN104922468A CN 104922468 A CN104922468 A CN 104922468A CN 201510278074 A CN201510278074 A CN 201510278074A CN 104922468 A CN104922468 A CN 104922468A
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Abstract
The invention relates to a heat-from-throat-clearing and yin-nourishing composition and a preparation method thereof. The composition comprises dendrobium officinale, a radix astragali extract, herba houttuyniae, platycodon grandiflorum, licorice and menthol. The heat-from-throat-clearing and yin-nourishing composition has the advantages that the obtained composition is safe and reliable to take, and has obvious functions of clearing heat from throat and nourishing yin.
Description
Technical field
The present invention relates to a kind of compositions, be specifically related to a kind of composition and method of making the same of moistening and cleaning throat yin nourishing.
Background technology
Day by day severe along with people's living environment, the crowd suffering from throat class disease is more and more higher, such as chronic pharyngitis.
Pharyngitis is under pharyngeal mucosa, mucosa and adenoid diffuse inflammation, often with other upper respiratory disease, is a kind of disease of pharynx very common in crowd.Concrete symptom is: pharyngeal discomfort, has foreign body sensation, irritative cough, drying, swells, blocks, pruritus etc.At present, the Therapeutic Method for pharyngitis has operative treatment, Microendoscopic radiofrequency ablation therapy and Drug therapy.Wherein operative treatment, Microendoscopic radiofrequency ablation therapy has good curative effect to early stage patient, but its treatment cost is expensive, is easily accepted by patient.Although the product kind for the treatment of pharyngitis is in addition many, mostly expensive and poor effect.Some medicines, dosage is large, but also can bring many side effect.
Summary of the invention
The object of this invention is to provide a kind of compositions of moistening and cleaning throat yin nourishing.
Another object of the present invention is to provide the preparation method of said composition.
The technical solution used in the present invention is a kind of compositions of moistening and cleaning throat yin nourishing, and said composition comprises Herba Dendrobii, Radix Astragali extract, Herba Houttuyniae, Radix Platycodonis, Radix Glycyrrhizae and Mentholum.
As preferably, said composition is made up of the component of following parts by weight: Herba Dendrobii 20 ~ 40 parts, Radix Astragali extract 5 ~ 15 parts, Herba Houttuyniae 15 ~ 55 parts, Radix Platycodonis 10 ~ 20 parts, 10 ~ 20 parts, Radix Glycyrrhizae and Mentholum 1 ~ 10 part.
As preferably, said composition is made up of the component of following parts by weight: Herba Dendrobii 30 parts, Radix Astragali extract 10 parts, Herba Houttuyniae 25 parts, Radix Platycodonis 14 parts, 14 parts, Radix Glycyrrhizae and Mentholum 7 parts.
As preferably, described Herba Dendrobii is dendrobium candidum ultrafine powder.
As preferably, described Radix Astragali extract is raw material by the Radix Astragali, through water extraction, concentrated, dry, obtained.
As preferably, described compositions also comprises one or more products that acceptable adjuvant is made on food.
Described on food acceptable adjuvant be selected from one or more the mixture in Fruit powder, edible essence, sweeting agent, acidic flavoring agent, filler, lubricant, antiseptic, suspending agent, food coloring, diluent, emulsifying agent, disintegrating agent or plasticizer.
As preferably, Fruit powder is a kind of or both the above mixture in orange powder, orange powder, Fructus Citri Limoniae powder, cherry powder, apple powder or coconut palm powder.But those skilled in the art think that feasible Fruit powder is all within protection scope of the present invention, and Fruit powder kind is not limited thereto, and the present invention does not limit at this.
As preferably, edible essence is a kind of or both the above mixture in flavoring orange essence, orange essence, Fructus Citri Limoniae essence, cherry essence, Mentholum, apple essence or coconut palm essence.But those skilled in the art think that feasible edible essence is all within protection scope of the present invention, and edible essence kind is not limited thereto, and the present invention does not limit at this.
In order to increase the mouthfeel of compositions, sweeting agent also can be added to increase sugariness.As preferably, sweeting agent is a kind of or both the above mixture in sucralose, acesulfame potassium, aspartame or mogroside.But those skilled in the art think that feasible sweeting agent is all within protection scope of the present invention, and sweeting agent kind is not limited thereto, and the present invention does not limit at this.
As preferably, acidic flavoring agent is a kind of or both the above mixture in citric acid, malic acid, lactic acid or citric acid.But those skilled in the art think that feasible acidic flavoring agent is all within protection scope of the present invention, and acidic flavoring agent kind is not limited thereto, and the present invention does not limit at this.
Filler refers to the weight and volume increasing tablet, is beneficial to the adjuvant of tabletting.Filler as tablet requires that mobility, compressibility are good, and adhesion is strong, has larger saturation to medicine.As preferably, filler is a kind of or both the above mixture in fructose, sugar alcohols, sucrose, starch, pregelatinized Starch, microcrystalline Cellulose or dextrin.But those skilled in the art think that feasible disintegrating agent is all within protection scope of the present invention, and filler kind is not limited thereto, and the present invention does not limit at this.
Lubricant refers to the adjuvant that can reduce frictional force between tablet and die wall, makes tabletting difficulty to prevent frictional force large, and when can make tabletting, pressure distribution is even, and makes the even density of tablet, can also improve the outward appearance of tablet, makes tablet surface light, smooth.As preferably, lubricant is a kind of or both the above mixture in Pulvis Talci, magnesium stearate, silicon dioxide or stearic acid.But those skilled in the art think that feasible lubricant is all within protection scope of the present invention, and lubricant kind is not limited thereto, and the present invention does not limit at this.
As preferably, antiseptic is a kind of or both the above mixture in sodium benzoate, Potassium Benzoate, sorbic acid methyl ester, ethylparaben or P-hydroxybenzoic acid phenyl ester.But those skilled in the art think that feasible antiseptic is all within protection scope of the present invention, and antiseptic kind is not limited thereto, and the present invention does not limit at this.
As preferably, suspending agent is a kind of or both the above mixture in sodium carboxymethyl cellulose, sodium alginate or Cera Flava.But those skilled in the art think that feasible suspending agent is all within protection scope of the present invention, and suspending agent kind is not limited thereto, and the present invention does not limit at this.
As preferably, food coloring is a kind of or both the above mixture in caramel color, Gardenia Yellow, curcumin or chlorophyll.But those skilled in the art think that feasible food coloring is all within protection scope of the present invention, and food coloring kind is not limited thereto, and the present invention does not limit at this.
As preferably, diluent a kind of or both above mixture that to be edible vegetable oil, propylene glycol or molecular weight be in the Polyethylene Glycol of 400 ~ 6000.But those skilled in the art think that feasible diluent is all within protection scope of the present invention, and diluent kind is not limited thereto, and the present invention does not limit at this.
As preferably, emulsifying agent is S-40, sodium stearoyl lactate/calcium, diacetyl tartarate monoglyceride, sucrose fatty acid ester, molecular weight be 400 ~ 6000 Polyethylene Glycol or distillation monoglyceride in a kind of or both above mixture.But those skilled in the art think that feasible emulsifying agent is all within protection scope of the present invention, and emulsifier is not limited thereto, and the present invention does not limit at this.
The Main Function of disintegrating agent is to eliminate because binding agent or the adhesion that forms tablet by pressurizeing make the rapid disintegrate of tablet, makes tablet can play drug effect rapidly.As preferably, disintegrating agent is a kind of or both the above mixture in dried starch, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, crospolyvinylpyrrolidone or sodium carboxymethyl cellulose.But those skilled in the art think that feasible disintegrating agent is all within protection scope of the present invention, and filler kind is not limited thereto, and the present invention does not limit at this.
As preferably, plasticizer is a kind of or both the above mixture in glycerol, sodium carboxymethyl cellulose, sorbitol or oleamide sodium sulfonate.But those skilled in the art think that feasible plasticizer is all within protection scope of the present invention, and plasticizer kind is not limited thereto, and the present invention does not limit at this.
As preferably, the dosage form of described compositions is selected from the one in tablet, granule, pill, capsule, powder or liquid preparation.
The present invention also provides a kind of preparation method of described compositions, comprises the following steps: by formula proportion, by all components mixing in described compositions, to obtain final product.
The present invention also provides the application of a kind of described compositions in the health product of moistening and cleaning throat.
Beneficial effect of the present invention is: recipe design is reasonable, and compatibility is rigorous, and edible safety is reliable, and resulting composition has the function of significant moistening and cleaning throat and YIN nourishing.
Detailed description of the invention
For making those skilled in the art understand production technology of the present invention and technique effect in detail, introduce application of the present invention and technique effect further with concrete production instance below.
Embodiment 1
By weight, take dendrobium candidum ultrafine powder 30 parts, Radix Astragali extract 10 parts, Herba Houttuyniae powder 25 parts, balloonflower powder 14 parts, Radix Glycyrrhizae powder 14 parts and Mentholum 7 parts, mixing, obtains electuary.
Embodiment 2
By weight, take dendrobium candidum ultrafine powder 40 parts, Radix Astragali extract 5 parts, Herba Houttuyniae powder 15 parts, balloonflower powder 20 parts, Radix Glycyrrhizae powder 10 parts and Mentholum 1 part, add appropriate magnesium stearate and starch, mixing, tabletting, obtains tablet.
Embodiment 3
By weight, take dendrobium candidum ultrafine powder 20 parts, Radix Astragali extract 15 parts, Herba Houttuyniae powder 55 parts, balloonflower powder 10 parts, Radix Glycyrrhizae powder 20 parts and Mentholum 10 parts, add suitable amount of sucrose, mixing, granulate, obtain granule.
Embodiment 4
By weight, take dendrobium candidum ultrafine powder 25 parts, Radix Astragali extract 12 parts, Herba Houttuyniae powder 20 parts, balloonflower powder 18 parts, Radix Glycyrrhizae powder 14 parts and Mentholum 2 parts, add proper honey, mixing, pill, obtains pill.
Embodiment 5
By weight, take dendrobium candidum ultrafine powder 35 parts, Radix Astragali extract 8 parts, Herba Houttuyniae powder 50 parts, balloonflower powder 14 parts, Radix Glycyrrhizae powder 12 parts and Mentholum 6 parts, decoct with water, filter, fill, obtains oral liquid.
For verifying technique effect of the present invention, the following test of special do:
Function of moistening and cleaning throat effect
120 routine chronic pharyngitis crowds are divided into test-meal group and negative control group at random.Matched group takes placebo and test group takes this product, every day 3 times, and each 1 bag, takes 15 days continuously.Result of the test is in table 1.
Table 1
As can be seen from the above table, after test group takes 15 days continuously, pharyngeal symptom, somatic feature score obviously reduce, and have statistical significance with matched group comparing difference.Product of the present invention has function of moistening and cleaning throat.
Edible product of the present invention also has the effect improving deficiency of YIN symptom, has substantially all making moderate progress of night sweat symptom in such as above-mentioned test-meal crowd.
Finally it should be noted that, above embodiment is the unrestricted technical scheme of the present invention in order to explanation only, although with reference to above-described embodiment to invention has been detailed description, those skilled in the art are to be understood that, still can modify to the present invention or equivalent replacement, and not departing from any modification or partial replacement of the spirit and scope of the present invention, it all should be encompassed in right of the present invention.
Claims (9)
1. a compositions for moistening and cleaning throat yin nourishing, is characterized in that, said composition comprises Herba Dendrobii, Radix Astragali extract, Herba Houttuyniae, Radix Platycodonis, Radix Glycyrrhizae and Mentholum.
2. the compositions of a kind of moistening and cleaning throat yin nourishing according to claim 1, it is characterized in that, said composition is made up of the component of following parts by weight: Herba Dendrobii 20 ~ 40 parts, Radix Astragali extract 5 ~ 15 parts, Herba Houttuyniae 15 ~ 55 parts, Radix Platycodonis 10 ~ 20 parts, 10 ~ 20 parts, Radix Glycyrrhizae and Mentholum 1 ~ 10 part.
3. the compositions of a kind of moistening and cleaning throat yin nourishing according to claim 2, is characterized in that, said composition is made up of the component of following parts by weight: Herba Dendrobii 30 parts, Radix Astragali extract 10 parts, Herba Houttuyniae 25 parts, Radix Platycodonis 14 parts, 14 parts, Radix Glycyrrhizae and Mentholum 7 parts.
4. the compositions of a kind of moistening and cleaning throat yin nourishing according to claim 1, is characterized in that, described Herba Dendrobii is dendrobium candidum ultrafine powder.
5. the compositions of a kind of moistening and cleaning throat yin nourishing according to claim 1, is characterized in that, described Radix Astragali extract is raw material by the Radix Astragali, through water extraction, concentrated, dry, obtained.
6. the compositions of a kind of moistening and cleaning throat yin nourishing according to any one of claim 1-5, is characterized in that: described compositions also comprises one or more products that acceptable adjuvant is made on food.
7. the compositions of a kind of moistening and cleaning throat yin nourishing according to claim 6, is characterized in that, the dosage form of described compositions is selected from the one in tablet, granule, pill, capsule, powder or liquid preparation.
8. based on a preparation method for compositions described in claim 7, it is characterized in that, comprise the following steps: by formula proportion, by all components mixing in described compositions, to obtain final product.
9. the application of compositions in the health product of moistening and cleaning throat according to any one of claim 1-8.
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| CN201510278074.6A CN104922468A (en) | 2015-05-28 | 2015-05-28 | Heat-from-throat-clearing and yin-nourishing composition and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107095968A (en) * | 2017-04-24 | 2017-08-29 | 许昌学院 | A kind of anti-haze effervescent tablet of relieving sore-throat clearing lung-heat and preparation method thereof |
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| CN101549012A (en) * | 2008-04-01 | 2009-10-07 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine composition for treating throat diseases and preparation method thereof |
| CN101549016A (en) * | 2008-04-01 | 2009-10-07 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine composition for treating acute and chronic pharyngitis and preparation method thereof |
| CN103127396A (en) * | 2013-03-19 | 2013-06-05 | 云南云尚生物技术有限公司 | Preparation with laryngopharynx clearing and moistening effects and preparation method of preparation |
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2015
- 2015-05-28 CN CN201510278074.6A patent/CN104922468A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101549012A (en) * | 2008-04-01 | 2009-10-07 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine composition for treating throat diseases and preparation method thereof |
| CN101549016A (en) * | 2008-04-01 | 2009-10-07 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine composition for treating acute and chronic pharyngitis and preparation method thereof |
| CN103127396A (en) * | 2013-03-19 | 2013-06-05 | 云南云尚生物技术有限公司 | Preparation with laryngopharynx clearing and moistening effects and preparation method of preparation |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107095968A (en) * | 2017-04-24 | 2017-08-29 | 许昌学院 | A kind of anti-haze effervescent tablet of relieving sore-throat clearing lung-heat and preparation method thereof |
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Application publication date: 20150923 |
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