CN104920884A - Anion feed additive for cows as well as preparation method and application of anion feed additive - Google Patents
Anion feed additive for cows as well as preparation method and application of anion feed additive Download PDFInfo
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- CN104920884A CN104920884A CN201510355430.XA CN201510355430A CN104920884A CN 104920884 A CN104920884 A CN 104920884A CN 201510355430 A CN201510355430 A CN 201510355430A CN 104920884 A CN104920884 A CN 104920884A
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Abstract
The invention discloses an anion feed additive for cows. The anion feed additive is prepared from the following raw materials in parts by weight: 18 parts of ammonium chloride, 20 parts of magnesium sulphate, 7 parts of magnesium chloride, 4 parts of calcium sulphate, 26 parts of bran, 17 parts of corn and 8 parts of starch. The invention further provides a preparation method and application of the anion feed additive. The anion feed additive for the cows as well as the preparation method and the application of the anion feed additive, which are disclosed by the invention, have the benefits that the PH value of urine and the contents of Ca2+, P3- and Mg2+ in serum of a multiparous cow can be effectively regulated, so that postpartum paralysis of the cow is prevented; the anion additive is added 2-3 weeks before parturition of the multiparous cow, so that the postpartum paralysis and secondary diseases of retained placenta, the postpartum paralysis, metritis and the like can be effectively prevented; hybridization of the cow is easy, and the conception rate during sexual period is high; besides lactation peak is early, the recovery of a womb is facilitated, and the reproductive property of the cow is improved; besides the price is lower than that of a conventional product on sell, so that medical cost and human resources are reduced, and the healthy development of dairy industry is facilitated.
Description
Technical field
The present invention relates to feed additive field, be specifically related to a kind of milk cow anion feed addictive and its preparation method and application.
Background technology
In recent years, China's dairy development speed is swift and violent, and postpartum paralysis incidence of disease in cattle farm is very high, causes huge economic loss to milk cow production.At present, the most frequently used way is for preventing postpartum paralysis in milk cow antenatal 2-3 week by adding anionic additive, and domestic what generally adopt is Ai Libao (Animate) anionic additive of import, although effect is rather good, expensive.There is postpartum paralysis, by supplementing a large amount of sugar-salt-water and calcium preparation treatment, proving effective though can get instant result, easily recurring, a large amount of manpower and financial resources need be spent, cause tremendous influence to production simultaneously.
Summary of the invention
Object of the present invention is exactly for above-mentioned defect of the prior art, provides a kind of milk cow anion feed addictive and its preparation method and application.
To achieve these goals, technical scheme provided by the invention is: a kind of milk cow anion feed addictive, is prepared by the following raw material according to parts by weight: ammonium chloride 18 parts, 20 parts, magnesium sulfate, 7 parts, magnesium chloride, 4 parts, calcium sulfate, 26 parts, wheat bran, corn 17 parts, starch 8 parts.
Second object of the present invention there is provided the preparation method of above-mentioned a kind of milk cow anion feed addictive, comprises the following steps:
1) after food-grade industrial chemicals ammonium chloride, magnesium sulfate, magnesium chloride and calcium sulfate being taken according to proportioning, add one by one with the order of calcium sulfate, magnesium chloride, ammonium chloride, magnesium sulfate and mix, obtaining food-grade chemical industry mixed material;
2), after cereals raw material wheat bran, corn and starch being taken according to proportioning, add one by one with the order of starch, corn, wheat bran and mix, obtaining cereals mixed material;
3) the food-grade chemical industry mixed material and the step 2 that step 1) are obtained) the cereals mixed material that obtains mixes, and can obtain milk cow anion feed addictive after granulation.
3rd object of the present invention there is provided the application of above-mentioned a kind of milk cow anion feed addictive in the feed for the preparation of prevention milk cow postpartum paralysis.
Further, above-mentioned application is described milk cow anion feed addictive is added to milk cow entirely to mix in daily ration, according to weight ratio anion feed addictive: complete mixed daily ration is 1:13, and addition is every cow head 0.45kg/ days.
A kind of milk cow anion feed addictive and its preparation method and application provided by the invention, its beneficial effect is: can effectively regulate Ca in milking cow urine pH value and serum
2+, P
3-with Mg
2+content, thus prevention milk cow postpartum paralysis.Postpartum paralysis and secondary disease retention of afterbirth, postpartum paralysis and hysteritis etc. can be effectively prevented after 2-3 week adding anionic additive before multiparity cow birth, and ox easily breeds, non-return rate is high, peak of lactation, early, facilitates the recovery in uterus, improves the reproductive performance of milk cow simultaneously, simultaneously, price, lower than existing commercially available prod, has been saved medical fee and has decreased manpower, having facilitated the sound development of milk industry.
Accompanying drawing explanation
Fig. 1 is the mean variation result of test ox urine ph values.
Fig. 2 is calcium ion mean variation result in test cow's serum.
Fig. 3 is magnesium ion mean variation result in test cow's serum.
Fig. 4 is phosphonium ion mean variation result in test cow's serum.
Detailed description of the invention
embodiment 1:
1, additive and preparation method:
A kind of milk cow anion feed addictive, is prepared by following raw material: ammonium chloride 18kg, magnesium sulfate 20kg, magnesium chloride 7kg, calcium sulfate 4kg, wheat bran 26kg, corn 17kg, starch 8kg.
Its preparation method, comprises the following steps:
1) after food-grade industrial chemicals ammonium chloride, magnesium sulfate, magnesium chloride and calcium sulfate being taken according to proportioning, add one by one with the order of calcium sulfate, magnesium chloride, ammonium chloride, magnesium sulfate and mix, obtaining food-grade chemical industry mixed material;
2), after cereals raw material wheat bran, corn and starch being taken according to proportioning, add one by one with the order of starch, corn, wheat bran and mix, obtaining cereals mixed material;
3) the food-grade chemical industry mixed material and the step 2 that step 1) are obtained) the cereals mixed material that obtains mixes, and can obtain milk cow anion feed addictive after granulation, particle is canescence, diameter is 5mm, length is the cylindric of 10mm.
2, additive campaign:
2.1 test ox palatability testings:
Directly anionic additive is sprinkling upon forage grass or milk cow TMR(mixed daily ration entirely) on, test ox searches for food bad, if anionic additive and TMR Homogeneous phase mixing are fed, does not affect ox and searches for food; In order to allow test Niu Shiying search for food, anionic additive first 3 days additions should from less to more, and within the 4th day, press 0.45kg/d to farrowing interval and add, test ox all can normally search for food.In process of feeding, test ox is had no adverse effects.
2.2 test ox urine detection tests:
During on-test to cow birth, every day to collect in anionic additive and Ai Libao (Animate) the 2-6 hour mode by artificial chamber pot of feeding and test ox urine 1 time every day, the not free restriction of control group, takes back use for laboratory PHS-3C type acidometer and detects its pH value by urine.Result shows, tests first 3 days, and 3 groups of test ox urine PH are all about 8.3, and 1,2 group started to decline at 4-5 days, and within the 6th day, drop to about 7.0, then PH is basically stable at 6.0-7.0, and the 3rd group of PH is stabilized in about 8.0 always.The mean variation of test ox urine ph values as shown in Figure 1.
2.3 test bovine blood examination and analysb:
Take a blood sample 1 time before the test, take a blood sample 1 time after feed anionic additive and Ai Libao (Animate) every 7 days, until childbirth, taking a blood sample 1 time within 12-24 hour postpartum, takes a blood sample 2 times in interval for 2 days again.Every afternoon jugular vein blood collection 10ml, slant setting overnight, separation of serum ,-4 DEG C of Cord blood, adopt azo arsenic III colorimetric method to the Ca in serum
2+, P
3-, Mg
2+etc. measuring.
2.3.1 test calcium ion in cow's serum to detect:
Test group interpolation anionic additive after, Ca
2+mean value rises to some extent, and control group does not change substantially; Give a birth the same day, test group is down to 1.96 mmol/l, and control group is down to 1.78 mmol/l, and it is large that control group reduces amplitude; In the 4th day postpartum, test group rises to 2.08 mmol/l, and control group is upgraded to 1.94 mmol/l, and it is very fast that anionic group rises.In test cow's serum, calcium ion mean variation as shown in Figure 2.
2.3.2 test magnesium ion in cow's serum to detect:
Childbirth before and after test group and control group serum in Mg
2+the change of mean value is not obvious.In test cow's serum, magnesium ion mean variation as shown in Figure 3.
2.3.3 test phosphonium ion in cow's serum to detect:
Test group interpolation anionic additive after, P in serum
3-content comparatively control group rises to some extent; Give a birth the same day, two groups all obviously drop to about 2.4 mmol/l, but the 4th day postpartum, test group rises to 1.54 mmol/l, and control group only rises to 1.35 mmol/l, until the 7th day postpartum, and control group
p3-content and test group close.In test cow's serum, phosphonium ion mean variation as shown in Figure 4.
2.4. the clinical expanding test of ox is tested:
Select the milk cow 100 of the identical requirement of rearing conditions, be divided into 2 groups, often organize 50.1 group is test group, and every day adds anionic additive 0.45kg mixed feeding in milk cow TMR, and divide and feed for 2 times, 2 groups is control group, does not add any additive, complete mixed daily ration of only feeding.Result shows, test group 50 cow head, only have postpartum 1 cow head unknown cause generation hysterorrhexis and eliminate outside, all the other milk cows all do not fall ill, and the incidence of disease is 2%, and control group 50 cow head has 8 hairs raw retention of afterbirth postpartum, 1 the first-born clothing does not drain, 2 postpartum paralysises, and the incidence of disease is 22%.Two groups of test ox output of milk difference are not obvious.Add anion prevent disease situation as shown in table 1.
Table 1
。
By repeatedly groping processing conditions and clinical testing, and show with Animate contrast test, palatability and good stability, price is moderate, is applicable to domestic milk cow production.Prevention puerperal fever and subacute low blood calcium require that blood PH is reduced to the state of non-metabolic alkalosis.Owing to having close relevant (Davidson etc., 1995 between blood PH and urine PH; Gaynor etc., 1989; Jardon, 1995).Therefore, measure urine PH to become a kind of and very effectively whether serve due effect to the anionic additive in daily ration with deciding animal.After interpolation anionic additive and Animate, two groups of test ox urine PH maintain about 6.5 substantially, and un-added control group ox urine maintains about 8.0 always, illustrates that anionic additive serves due effect.After test ox TMR adds anionic additive, Ca in postpartum blood
2+with P
3-the comparatively control group recovered is fast, and Mg
2+change not obvious.Thus demonstrate, slight metabolic acidosis can prevent low blood calcium in postpartum.P
3-obviously, so after anionic additive of feeding, in bone, employing of calcium may be the main cause improving blood calcium concentration in change; Due to Ca in renal tubule
2+and Mg
2+reuptake mechanism identical (Samily etc., 1960), therefore Ca
2+concentration raising can suppress Mg
2+reuptake, anionic additive contains Mg in addition
2+, therefore Mg
2+change not obvious.The balance of blood calcium is a kind of absorption of complexity, output and recirculation mechanism (Goff etc., 1991).The intestinal absorption of calcium, the employing of skeletal calcium deposition to be preserved with the calcium of kidney mainly by hormone 1-25-(OH)2-D3 [1,25(OH) 2D3] and parathormone (PTH) control.Clinical expanding test, adding anionic additive through milking cow can effectively prevent the postpartum diseases such as retention of afterbirth, postpartum paralysis and hysteritis.Show according to cattle farm feedack, the test ox of adding anionic additive group easily breeds, and non-return rate is high, peak of lactation, early simultaneously, this is because after adding anionic additive, decrease retention of afterbirth, promote the recovery in uterus, improve the reproductive performance of milk cow.Though it is little on milk production of cow impact to add anionic additive, effectively prevents the disease such as postpartum paralysis and retention of afterbirth, considerably reduce manpower and medical expenses, facilitate the development of raising dairy cattle industry.
Therefore the present invention be a very promising prevention milk cow postpartum paralysis anion feed addictive.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. a milk cow anion feed addictive, is characterized in that, is to be prepared by the following raw material according to parts by weight: ammonium chloride 18 parts, 20 parts, magnesium sulfate, 7 parts, magnesium chloride, 4 parts, calcium sulfate, 26 parts, wheat bran, corn 17 parts, starch 8 parts.
2. a kind of milk cow preparation method of anion feed addictive according to claim 1, is characterized in that, comprise the following steps:
1) after food-grade industrial chemicals ammonium chloride, magnesium sulfate, magnesium chloride and calcium sulfate being taken according to proportioning, add one by one with the order of calcium sulfate, magnesium chloride, ammonium chloride, magnesium sulfate and mix, obtaining food-grade chemical industry mixed material;
2), after cereals raw material wheat bran, corn and starch being taken according to proportioning, add one by one with the order of starch, corn, wheat bran and mix, obtaining cereals mixed material;
3) the food-grade chemical industry mixed material and the step 2 that step 1) are obtained) the cereals mixed material that obtains mixes, and can obtain milk cow anion feed addictive after granulation.
3. a kind of milk cow as claimed in claim 1 application of anion feed addictive in the feed for the preparation of prevention milk cow postpartum paralysis.
4. application according to claim 3, is characterized in that, is described milk cow anion feed addictive to be added to milk cow entirely to mix in daily ration, according to weight ratio anion feed addictive: complete mixed daily ration is 1:13, and addition is every cow head 0.45kg/ days.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111528356A (en) * | 2020-05-20 | 2020-08-14 | 北京福乐维生物科技有限公司 | Preparation method of anion salt with good palatability for dairy cow perinatal period |
Citations (4)
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| CN101044886A (en) * | 2007-02-16 | 2007-10-03 | 新疆农垦科学院 | Premixed feed used specially for milk cow before perinatal period and its producing method |
| CN102150756A (en) * | 2010-12-13 | 2011-08-17 | 刘福元 | Health-care premix for pre-perinatal high-yield milk cows |
| CN103918916A (en) * | 2014-04-21 | 2014-07-16 | 吉林农业大学 | Feed additive for dairy cows at earlier perinatal stage |
| CN104413277A (en) * | 2013-08-29 | 2015-03-18 | 傅中伦 | Special feed for pregnant sows and production method of special feed |
-
2015
- 2015-06-25 CN CN201510355430.XA patent/CN104920884A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101044886A (en) * | 2007-02-16 | 2007-10-03 | 新疆农垦科学院 | Premixed feed used specially for milk cow before perinatal period and its producing method |
| CN102150756A (en) * | 2010-12-13 | 2011-08-17 | 刘福元 | Health-care premix for pre-perinatal high-yield milk cows |
| CN104413277A (en) * | 2013-08-29 | 2015-03-18 | 傅中伦 | Special feed for pregnant sows and production method of special feed |
| CN103918916A (en) * | 2014-04-21 | 2014-07-16 | 吉林农业大学 | Feed additive for dairy cows at earlier perinatal stage |
Non-Patent Citations (1)
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111528356A (en) * | 2020-05-20 | 2020-08-14 | 北京福乐维生物科技有限公司 | Preparation method of anion salt with good palatability for dairy cow perinatal period |
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Application publication date: 20150923 |