CN104873901A - Lavage fluid for bacterial vaginitis - Google Patents

Lavage fluid for bacterial vaginitis Download PDF

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Publication number
CN104873901A
CN104873901A CN201510300724.2A CN201510300724A CN104873901A CN 104873901 A CN104873901 A CN 104873901A CN 201510300724 A CN201510300724 A CN 201510300724A CN 104873901 A CN104873901 A CN 104873901A
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parts
herba
irrigating solution
bacterial vaginitis
weight portion
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邵风萍
马超
窦金玲
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The invention provides a lavage fluid for bacterial vaginitis, and by adopting the technical scheme, an obvious treatment effect is achieved through selection of traditional Chinese medicine and quantitative optimal design. Litsea cubeba has the effects of regulating qi, removing stasis, detoxifying and reducing swelling and is used as a main component, so as to achieve an obvious inhibiting effect on various pathogenic microorganisms; nervilia fordii has the effecct of clearing toxicity, and the bacteriostatic effect can be further increased by adding a reasonable amount of nervilia fordii in a formula; bittersweet is the whole herb, has the bitterly cold flavor, is in lung, liver and spleen channels and is favorable for alleviating the development of inflammation; in addition, rhizoma arisaematis has the effects of dispelling wind and relieving convulsion. According to the lavage fluid, the treatment effect and the treatment speed of the lavage fluid on the bacterial vaginitis can be obviously increased by adding a reasonable amount of corydalis amabilis, semen litchi, turmeric, epimedium and fenugreek on the basis of the components, and additionally, the complication probability of the upper genital tract infection can be reduced.

Description

A kind of irrigating solution for bacterial vaginitis
Technical field
The present invention relates to gynecological's Prevention of Infectious Diseases technical field, be specifically related to a kind of irrigating solution for bacterial vaginitis.
Background technology
Bacterial vaginitis (BV) is the mixed infection of a kind of per vaginam Gartner bacterium and some anaerobic bacterias, and cause intravaginal microecological balance to be lacked of proper care, the vaginal secretions caused increases, and leucorrhea has fish bad smell and the scorching hot syndrome of pruritus vulvae.Haemophilus vaginitis, Corynebacterium vaginitis, anaerobic bacteria vaginosis inflammation, Gardnerella Vaginalis Vaginitis etc. can be divided into.Primary disease also passability contagion, in the crowd of sexual relationship confusion, sickness rate is higher.Secretions plate coating checking can find a large amount of pyocyte, finds pathogenic bacterium.
In prior art, general treatment and Drug therapy are divided into the treatment of bacterial vaginitis.Wherein general treatment is mainly through keeping pudendum cleaning, drying, avoids scratching, and avoids pungent food in diet simultaneously.And Drug therapy is divided into medicine for external use and oral medicine two kinds, wherein medicine for external use with metronidazole suppository for representative, its clear curative effect but also exist in some sufferer and use inconvenience and the ill symptoms such as anaphylaxis; And oral medicine mainly comprises metronidazole and the large class of broad ectrum antibiotic two, wherein metronidazole application is the most general, but be therefore limit it to a certain extent to use because adverse reaction rate is higher equally, and have to be hoisted in curative effect with the antibiotic that methylpartricin, thiamphenicol etc. are representative, and along with the phenomenon of medicine and hygiene fields abuse of antibiotics day by day serious, therefore should suitably reduce antibiotic dependence equally in the treatment of bacterial vaginitis.
In addition, researcher in prior art, is had to attempt by natural drug seeking breakthrough, and the technological deficiency that the natural drug of prior art is slow to the treatment ubiquity onset of bacterial vaginitis, uncertain therapeutic efficacy is cut.If therefore can develop, a kind of curative effect is given prominence to, the natural drug for bacterial vaginitis of onset speed, then can expand patient's scope, can promote therapeutic effect again simultaneously.
Summary of the invention
The present invention is intended to the technological deficiency for prior art, provides a kind of irrigating solution for bacterial vaginitis, to solve the technical problem that in prior art, bacterial vaginitis medicine curative effect is poor.
Another technical problem that the present invention solves is the onset speed of the sky medicine of a warm nature thing promoted for bacterial vaginitis treatment.
The technical problem again that the present invention solves is utilizing medicine to carry out avoiding untoward reaction in the process of bacterial vaginitis treatment.
For realizing above technical purpose, the present invention by the following technical solutions:
A kind of irrigating solution for bacterial vaginitis, comprise the composition of following weight portion: Fructus Litseae 5 ~ 7 parts, Folium Nerviliae fordii 3 ~ 5 parts, Herba Solani Lyrati 3 ~ 5 parts, Rhizoma Corydalis Decumbentis 2 ~ 3 parts, Herba Epimedii 2 ~ 4 parts, Rhizoma Arisaematis 5 ~ 7 parts, Semen Litchi 2 ~ 3 parts, Herba Houttuyniae 1 ~ 2 part, Semen Trigonellae 1 ~ 2 part, 1 ~ 2 part, Rhizoma Curcumae Longae, 30 parts, water.
Preferably, the Herba Abri of 1 ~ 2 weight portion is also comprised.
Preferably, the Herba Pogostemonis of 1 ~ 2 weight portion is also comprised.
Preferably, the caraway seeds of 1 ~ 2 weight portion is also comprised.
Preferably, the Aloe of 1 ~ 2 weight portion is also comprised.
Preferably, described irrigating solution is grouped into by the one-tenth of following weight portion: Fructus Litseae 6 parts, Folium Nerviliae fordii 4 parts, Herba Solani Lyrati 4 parts, Rhizoma Corydalis Decumbentis 2.5 parts, Herba Epimedii 3 parts, Rhizoma Arisaematis 6 parts, Semen Litchi 2.5 parts, Herba Houttuyniae 1.5 parts, Semen Trigonellae 1.5 parts, 1.5 parts, Rhizoma Curcumae Longae, 30 parts, water.
Preferably, described irrigating solution is grouped into by the one-tenth of following weight portion: Fructus Litseae 5.5 parts, Folium Nerviliae fordii 3.5 parts, Herba Solani Lyrati 3.5 parts, Rhizoma Corydalis Decumbentis 2.2 parts, Herba Epimedii 2.7 parts, Rhizoma Arisaematis 5.6 parts, Semen Litchi 2.3 parts, Herba Houttuyniae 1.2 parts, Semen Trigonellae 1.2 parts, 1.2 parts, Rhizoma Curcumae Longae, Herba Abri 1.5 parts, Herba Pogostemonis 1.5 parts, caraway seeds 1.5 parts, Aloe 1.5 parts, 30 parts, water.
Irrigating solution for bacterial vaginitis of the present invention, mentioned component and formula is utilized to be mixed to get, can be such as be mixed to get mixed liquor after formula components being pulverized, also can be, by after each composition squeezing juice, juice is mixed to get mixed liquor by formula.The using method of irrigating solution of the present invention is, by injection device, irrigating solution is delivered to intravaginal, irrigating solution is filled and keeps 5 ~ 10min in intravaginal, then changes position and irrigating solution is flowed out naturally, then with clean water pudendum.
In above technical scheme, by Chinese medicine selection, quantitative optimal design, obtain the irrigating solution of the present invention for bacterial vaginitis.Wherein Fructus Litseae composition refers to the blade of Fructus Litseae, there is effect of eliminating stagnation of regulating the flow of vital energy, removing toxic substances and promoting subsidence of swelling, significant inhibitory action can be played to microorganisms such as haemophilus vaginitis, Corynebacterium vaginitis, anaerobic bacteria vaginosis inflammation, Gartner bacterium using it as main component; Folium Nerviliae fordii possesses pestilence effect clearly equally, and the Folium Nerviliae fordii adding reasonable amount in formula can promote antibacterial curative effect further; Herba Solani Lyrati composition refers to its herb, nature and flavor bitter cold, returns lung, liver, spleen channel, contributes to the development of amelioration of inflammation; In addition, Rhizoma Arisaematis has the effect of expellingging wind and relieving convulsion.And Rhizoma Corydalis Decumbentis, Semen Litchi and Rhizoma Curcumae Longae are originally used for invigorating blood circulation active, promoting the circulation of QI to relieve pain, Herba Epimedii, Semen Trigonellae are originally used for warming the kidney to activate YANG, dispersing cold for relieving pain, the discovery that the present invention is surprised, to significantly can promote irrigating solution after mentioned component rational proportion to the therapeutic effect of bacterial vaginitis and treatment speed, the probability of concurrent upper reproductive tract infection can be reduced simultaneously.
In optimal technical scheme, find in irrigating solution, add the probability that the compositions such as Herba Abri, Herba Pogostemonis, caraway seeds, Aloe can reduce the concurrent pelvic inflammatory disease of bacterial vaginitis.In the application in TCM of prior art, Herba Abri is mainly used in heat-clearing and toxic substances removing, dispersing the depressed liver-QI for alleviating pain, Herba Pogostemonis eliminating turbid pathogen with aromatics, delivers expelling summer-heat, and Aloe, caraway seeds use mainly as food or flavoring agent.That is, interpolation mentioned component can reduce effect of the concurrent upper reproductive tract infection probability of bacterial vaginitis is beyond thought.
In sum, formula components of the present invention is reasonable, and curative effect is outstanding and onset is very fast, and clinical experiment finds that the patients recovery rate of this irrigating solution of external is very fast, and complication probability is lower simultaneously.In addition, cost of the present invention is lower, is easy to realize, and has outstanding promotion prospect.
Detailed description of the invention
Below will be described in detail the specific embodiment of the present invention.In order to avoid too much unnecessary details, in the examples below to belonging to known structure or function will not be described in detail.Apart from outside definition, technology used in following examples and scientific terminology have the identical meanings generally understood with those skilled in the art of the invention.
Embodiment 1
For an irrigating solution for bacterial vaginitis, be grouped into by the one-tenth of following weight portion: Fructus Litseae 5 parts, Folium Nerviliae fordii 3 parts, Herba Solani Lyrati 3 parts, Rhizoma Corydalis Decumbentis 2 parts, Herba Epimedii 2 parts, Rhizoma Arisaematis 5 parts, Semen Litchi 2 parts, Herba Houttuyniae 1 part, Semen Trigonellae 1 part, 1 part, Rhizoma Curcumae Longae, 30 parts, water.
Embodiment 2
For an irrigating solution for bacterial vaginitis, be grouped into by the one-tenth of following weight portion: Fructus Litseae 7 parts, Folium Nerviliae fordii 5 parts, Herba Solani Lyrati 5 parts, Rhizoma Corydalis Decumbentis 3 parts, Herba Epimedii 4 parts, Rhizoma Arisaematis 7 parts, Semen Litchi 3 parts, Herba Houttuyniae 2 parts, Semen Trigonellae 2 parts, 2 parts, Rhizoma Curcumae Longae, 30 parts, water.
Embodiment 3
For an irrigating solution for bacterial vaginitis, be grouped into by the one-tenth of following weight portion: Fructus Litseae 6 parts, Folium Nerviliae fordii 4 parts, Herba Solani Lyrati 4 parts, Rhizoma Corydalis Decumbentis 2.5 parts, Herba Epimedii 3 parts, Rhizoma Arisaematis 6 parts, Semen Litchi 2.5 parts, Herba Houttuyniae 1.5 parts, Semen Trigonellae 1.5 parts, 1.5 parts, Rhizoma Curcumae Longae, 30 parts, water.
Embodiment 4
For an irrigating solution for bacterial vaginitis, be grouped into by the one-tenth of following weight portion: Fructus Litseae 5.5 parts, Folium Nerviliae fordii 4.5 parts, Herba Solani Lyrati 4.5 parts, Rhizoma Corydalis Decumbentis 2.3 parts, Herba Epimedii 3.3 parts, Rhizoma Arisaematis 5.8 parts, Semen Litchi 2.1 parts, Herba Houttuyniae 1.4 parts, Semen Trigonellae 1.9 parts, 1.3 parts, Rhizoma Curcumae Longae, Herba Abri 1.7 parts, 30 parts, water.
Embodiment 5
For an irrigating solution for bacterial vaginitis, be grouped into by the one-tenth of following weight portion: Fructus Litseae 6.5 parts, Folium Nerviliae fordii 3.5 parts, Herba Solani Lyrati 3.5 parts, Rhizoma Corydalis Decumbentis 2.9 parts, Herba Epimedii 2.3 parts, Rhizoma Arisaematis 6.3 parts, Semen Litchi 2.8 parts, Herba Houttuyniae 1.7 parts, Semen Trigonellae 1.2 parts, 1.4 parts, Rhizoma Curcumae Longae, Herba Pogostemonis 1.5 parts, Aloe 1 part, 30 parts, water.
Embodiment 6
For an irrigating solution for bacterial vaginitis, be grouped into by the one-tenth of following weight portion: Fructus Litseae 5.5 parts, Folium Nerviliae fordii 4.5 parts, Herba Solani Lyrati 4.5 parts, Rhizoma Corydalis Decumbentis 2.3 parts, Herba Epimedii 3.3 parts, Rhizoma Arisaematis 5.8 parts, Semen Litchi 2.1 parts, Herba Houttuyniae 1.4 parts, Semen Trigonellae 1.9 parts, 1.3 parts, Rhizoma Curcumae Longae, Herba Abri 2 parts, caraway seeds 1.4 parts, Aloe 2 parts, 30 parts, water.
Embodiment 7
For an irrigating solution for bacterial vaginitis, be grouped into by the one-tenth of following weight portion: Fructus Litseae 6.5 parts, Folium Nerviliae fordii 3.5 parts, Herba Solani Lyrati 3.5 parts, Rhizoma Corydalis Decumbentis 2.9 parts, Herba Epimedii 2.3 parts, Rhizoma Arisaematis 6.3 parts, Semen Litchi 2.8 parts, Herba Houttuyniae 1.7 parts, Semen Trigonellae 1.2 parts, 1.4 parts, Rhizoma Curcumae Longae, caraway seeds 1 part, 30 parts, water.
Embodiment 8
For an irrigating solution for bacterial vaginitis, be grouped into by the one-tenth of following weight portion: Fructus Litseae 5.5 parts, Folium Nerviliae fordii 3.5 parts, Herba Solani Lyrati 3.5 parts, Rhizoma Corydalis Decumbentis 2.2 parts, Herba Epimedii 2.7 parts, Rhizoma Arisaematis 5.6 parts, Semen Litchi 2.3 parts, Herba Houttuyniae 1.2 parts, Semen Trigonellae 1.2 parts, 1.2 parts, Rhizoma Curcumae Longae, Herba Abri 1.5 parts, Herba Pogostemonis 1.5 parts, caraway seeds 1.5 parts, Aloe 1.5 parts, 30 parts, water.
Embodiment 9
The present embodiment is for investigating the irrigating solution of above embodiment 1 ~ 8 to bacterial vaginitis patient outcomes.
Specific experiment method is: the irrigating solution selecting above embodiment 1 ~ 8, and simultaneously using metronidazole, methylpartricin, thiamphenicol, ampicillin four kinds of medicines as experiment contrast, often kind of medicine is respectively to 30 bacterial vaginitis patient administration.Wherein the application method of irrigating solution is: by injection device, irrigating solution is delivered to intravaginal, irrigating solution is filled and keeps 5 ~ 10min in intravaginal, then changes position and irrigating solution is flowed out naturally, then with clean water pudendum; The application method of other four kinds of control drug is for oral administration, concrete consumption Consult drug operation instructions, and investigate and cure the average time consumed, concurrent pelvic inflammatory disease probability and untoward reaction situation, experimental result is as follows:
Table 1 respectively organizes medicine to bacterial vaginitis patient outcomes experimental result
Cure spent time Concurrent pelvic inflammatory disease probability Untoward reaction probability
Embodiment 1 medicine 9 days 0 0
Embodiment 2 medicine 10 days 0 0
Embodiment 3 medicine 11 days 3.3% 0
Embodiment 4 medicine 9 days 6.6% 0
Embodiment 5 medicine 9 days 0 0
Embodiment 6 medicine 9 days 0 0
Embodiment 7 medicine 9 days 3.3% 0
Embodiment 8 medicine 8 days 0 0
Metronidazole 14 days 10% 6.6%
Methylpartricin 15 days 13.3% 0
Thiamphenicol 25 days 26.6% 0
Ampicillin 22 days 23.3% 3.3%
As shown in table 1, irrigating solution prepared by the present invention, to bacterial vaginitis determined curative effect, rapid-action, significantly can reduce the probability of the concurrent pelvic inflammatory disease of bacterial vaginitis simultaneously, and meanwhile, irrigating solution of the present invention is without skin irritation or the untoward reaction such as irritated.What above experimental result was strong demonstrates tank washing liquid of the present invention to the therapeutic effect of bacterial vaginitis.
Above embodiments of the invention have been described in detail, but described content is only preferred embodiment of the present invention, not in order to limit the present invention.All make in application range of the present invention any amendment, equivalent to replace and improvement etc., all should be included within protection scope of the present invention.

Claims (7)

1. the irrigating solution for bacterial vaginitis, it is characterized in that the composition comprising following weight portion: Fructus Litseae 5 ~ 7 parts, Folium Nerviliae fordii 3 ~ 5 parts, Herba Solani Lyrati 3 ~ 5 parts, Rhizoma Corydalis Decumbentis 2 ~ 3 parts, Herba Epimedii 2 ~ 4 parts, Rhizoma Arisaematis 5 ~ 7 parts, Semen Litchi 2 ~ 3 parts, Herba Houttuyniae 1 ~ 2 part, Semen Trigonellae 1 ~ 2 part, 1 ~ 2 part, Rhizoma Curcumae Longae, 30 parts, water.
2. irrigating solution according to claim 1, characterized by further comprising the Herba Abri of 1 ~ 2 weight portion.
3. irrigating solution according to claim 1, characterized by further comprising the Herba Pogostemonis of 1 ~ 2 weight portion.
4. irrigating solution according to claim 1, characterized by further comprising the caraway seeds of 1 ~ 2 weight portion.
5. irrigating solution according to claim 1, characterized by further comprising the Aloe of 1 ~ 2 weight portion.
6. irrigating solution according to claim 1, is characterized in that being grouped into by the one-tenth of following weight portion: Fructus Litseae 6 parts, Folium Nerviliae fordii 4 parts, Herba Solani Lyrati 4 parts, Rhizoma Corydalis Decumbentis 2.5 parts, Herba Epimedii 3 parts, Rhizoma Arisaematis 6 parts, Semen Litchi 2.5 parts, Herba Houttuyniae 1.5 parts, Semen Trigonellae 1.5 parts, 1.5 parts, Rhizoma Curcumae Longae, 30 parts, water.
7. irrigating solution according to claim 1, is characterized in that being grouped into by the one-tenth of following weight portion: Fructus Litseae 5.5 parts, Folium Nerviliae fordii 3.5 parts, Herba Solani Lyrati 3.5 parts, Rhizoma Corydalis Decumbentis 2.2 parts, Herba Epimedii 2.7 parts, Rhizoma Arisaematis 5.6 parts, Semen Litchi 2.3 parts, Herba Houttuyniae 1.2 parts, Semen Trigonellae 1.2 parts, 1.2 parts, Rhizoma Curcumae Longae, Herba Abri 1.5 parts, Herba Pogostemonis 1.5 parts, caraway seeds 1.5 parts, Aloe 1.5 parts, 30 parts, water.
CN201510300724.2A 2015-06-05 2015-06-05 Lavage fluid for bacterial vaginitis Pending CN104873901A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169272A (en) * 2015-09-30 2015-12-23 史立凤 Traditional Chinese medicine composition for scarflet fever treatment

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1191746A (en) * 1998-03-05 1998-09-02 韩殿卫 Inflammation curing Chinese medicine
CN101648003A (en) * 2008-08-13 2010-02-17 北京和润创新医药科技发展有限公司 Medicinal composition for treating gynecological inflammation and application thereof
CN104173549A (en) * 2014-08-22 2014-12-03 从江神瑶保健品有限公司 Medicated bath powder for treating gynecologic inflammation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1191746A (en) * 1998-03-05 1998-09-02 韩殿卫 Inflammation curing Chinese medicine
CN101648003A (en) * 2008-08-13 2010-02-17 北京和润创新医药科技发展有限公司 Medicinal composition for treating gynecological inflammation and application thereof
CN104173549A (en) * 2014-08-22 2014-12-03 从江神瑶保健品有限公司 Medicated bath powder for treating gynecologic inflammation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169272A (en) * 2015-09-30 2015-12-23 史立凤 Traditional Chinese medicine composition for scarflet fever treatment

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