CN104027700A - Traditional Chinese medicine composition for treating chronic prostatitis and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating chronic prostatitis and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method of the composition. The composition comprises the following components in parts by weight: 2-20 parts of rhizoma dioscoreae hypoglaucae, 2-20 parts of rhizoma acori graminei, 2-40 parts of pumpkin seed, 2-20 parts of ardisia japonica, 2-40 parts of semen coicis, 2-20 parts of dandelion, 2-40 parts of fructus alpiniae oxyphyllae, 2-20 parts of flatstem milkvetch seed, 2-20 parts of the fruit of Chinese wolfberry, 2-20 parts of spina gleditsiae, 2-20 parts of the seed of Chinese dodder, 2-40 parts of lindera aggregate and 2-40 parts of semen plantaginis. The composition can be prepared into powder or tea bags in dosage form. The preparation method comprises the following steps: crushing, baking, disinfecting and sterilizing the raw material medicines, thereby preparing the powder or the tea bags. The clinical tests show that the traditional Chinese medicine composition disclosed by the invention has the effects of tonifying deficiency, breaking stagnation to generate fresh, invigorating the kidney, strengthening Yang and the like, can improve the immunity of the organism and improve the state of prostatic fluid, is beneficial for fertilization, is rapid and stable to take the curative effect into play, is free of toxic or side effect and is a traditional Chinese healthcare medicine for treating chronic prostatitis.
Description
Technical field
The invention belongs to tcm field, be specifically related to a kind of Chinese medicine composition for the treatment of chronic prostatitis and preparation method thereof.
Background technology
Chronic prostatitis is andrology's common clinical disease, can affect the activity of sperm and cause male infertility.The etiology and pathology of at present relevant this disease is illustrated not yet completely, still feels thorny in treatment.Chronic prostatitis (precious jade " stream essence " by name, precious jade language is gaih baengc, mx maaih saengh yungz), precious jade doctor thinks " damp and hot poison is evil " obstruction " water channel ", cause " water channel " to regulate the hinge mistake degree of kidney and bladder, prostate and testis etc., the root of QI and blood is obstructed, and life can not be changed in the source of QI and blood, therefore cause " gas of ternary " can not be synchronous, and bring out smart plug, weakness of QI, abundant expectoration, mutually fiery high Sheng, oligospermia, the stagnation of QI etc., treatment take removing summer-heat poison evil, unclog the channel as main.For prescription, CHUANTAI, Ardisia japonica, Semen Cucurbitae, Rhizoma Acori Graminei, Spina Gleditsiae etc. are principal agent, coordinate Semen Coicis, Herba Taraxaci, Fructus Alpiniae Oxyphyllae, Semen Astragali Complanati, Fructus Lycii, Semen Cuscutae, Radix Linderae, Semen Plantaginis to form, and in side, have tonifying the kidney to consolidate the essence, the product of clearing away heat-damp and promoting diuresis, adopting both clearing heat method and tonification method, mends and does not stay heresy, does not just hinder clearly.Wherein CHUANTAI is controlled wetly, and Semen Cucurbitae is astringent or styptic treatment for spontaneous sweating; Ardisia japonica dampness removing, the pain relieving of the Fructus Gleditsia transfixation stasis of blood, drink simultaneously add let out clearly damp and hot, eliminate phlegm for resuscitation, the product of eliminating blood stasis to promote regeneration of blood, invigorating the spleen and replenishing QI, embody the clear meaning developing simultaneously of mending.Herba Taraxaci has the effect of antiinflammatory dampness removing, detoxicating, killing bacteria, inducing diuresis for treating stranguria syndrome.Research discovery, this prescription is better than norfloxacin or two matched groups of QIANLIEKANG to the clinical efficacy of chronic nonbacterial prostatitis.With the Antibiotic Susceptivity Test that this prescription carries out, show, this prescription has stronger antibacterial effect, and bacterial prostatitis is also had to directly antibacterial or bacteriostasis.This prescription has good result aspect the abnormal immune reaction that improves prostate fluid zinc, adjustment prostate part.It should be noted that the prostatitic antibiotic of many treatments all has impact in various degree to spermatogenesis and sperm function, prostatitis is accompanied to sterile person, this medicine treatment can improve prostatitis symptom, does not injure again sperm quality, thereby is conducive to become pregnant.
The definite cause of disease of chronic prostatitis it be unclear that, therefore western medical treatment adopts fluoroquinolones extensive pedigree antibiotics clinically, these medicines have the fat-soluble and lower protein binding power of the straight warp of very little molecule, height, thereby easily permeate prostata tissue performance curative effect.By 191 routine clinical observation result, show herein, behind the side of taking this medicine, prostatic fluid situation is obviously improved, this medicine group is better than quinolione group (P < 0.05) to the clinical efficacy of non-bacterial chronic prostatitis, and for bacillary chronic prostatitis, this medicine group and quinolione group curative effect zero difference (P > 0.05).This illustrates that this prescription has certain curative effect at antibiosis, and can significantly improve prostatitic symptom, its possible mechanism of action is, Spina Gleditsiae in this prescription, CHUANTAI, Semen Cucurbitae, Herba Taraxaci etc. have the Abnormal Blood Rheology of correcting prostate part, improve microcirculation, eliminate edema, promote glandular secretion, the effects such as state of muscle group dysfunction at the bottom of alleviation basin.The object of the present invention is to provide a kind of Chinese medicine composition and method of making the same for the treatment of chronic prostatitis, can improve male prostate liquid status within a short period of time, improve pregnancy rate.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of male prostatitis.This pharmaceutical composition adopt there is eliminating inflammation and expelling toxin, tonify deficiency replenishing essence, dampness removing eliminating stagnation, removing blood stasis to promote tissue regeneration, moisturize pain relieving, the medicinal herb components of the effect such as tonifying YIN promotes the production of body fluid, kidney invigorating and YANG supporting, promoting blood circulation to restore menstrual flow, the deficiencies in the prior art have been overcome, can improve male prostatitis state within a short period of time, improve pregnancy rate.
1. the present invention is achieved through the following technical solutions:
Its raw material, in weight portion, comprises CHUANTAI 2-20 part, Rhizoma Acori Graminei 2-20 part, Semen Cucurbitae 2-40 part, Ardisia japonica 2-20 part, Semen Coicis 2-40 part, Herba Taraxaci 2-20 part, Fructus Alpiniae Oxyphyllae 2-40 part, Semen Astragali Complanati 2-20 part, Fructus Lycii 2-20 part, Spina Gleditsiae 2-20 part, Semen Cuscutae 2-20 part, Radix Linderae 2-40 part, Semen Plantaginis 2-40 part.
The effect of the included raw material of Chinese medicine composition of the present invention:
CHUANTAI: have another name called Hypoglaucous Collett Yam Rhizome, bitter in the mouth, property is flat, enters Liver Channel, stomach warp, urinary bladder channel.Effect dampness removing removes turbid, wind expelling stagnation removing, for stranguria marked by chyluria, nebulousurine, leukorrhagia, rheumatic arthralgia, articular instability, lumbocrural pain.Clinically for treating the principal agent of male chronic prostatitis.
Semen Cucurbitae: sweet in the mouth, property is flat.The effect that has anthelmintic, detumescence.Be used for clinically male chronic prostatitis.
Rhizoma Acori Graminei: acrid in the mouth, hardship, warm in nature, GUIXIN, stomach warp.The effect that has regulate the flow of vital energy, invigorate blood circulation, fall apart wind, the eliminating phlegm that dries, has one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.
Spina Gleditsiae: acrid in the mouth, warm in nature.The effect that has detumescence poison holding, evacuation of pus, parasite killing.
Herba Taraxaci: sweet in the mouth, micro-hardship, cold in nature.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Multiplexly clinically treat urinary system infection.
Ardisia japonica: acrid in the mouth, property is flat.Have relieving cough and resolving phlegm, the effect of dispel the wind removing toxic substances, promoting blood circulation and stopping pain.Also for acute nephritis, urinary tract infection.
Semen Coicis: cool in nature, sweet in the mouth, light.Spleen invigorating eliminating dampness by diuresis, can be used for treating stranguria with turbid discharge, dysuria etc.Can enhancing immunity and antiinflammatory action, enhance metabolism.Semen Coicis can promote the metabolism of body inner blood and moisture, has the effects such as diuresis, antiinflammatory.
Radix Linderae: acrid in the mouth, warm in nature, enter spleen, lung, kidney, urinary bladder channel.Pleasant, dissipating depression of QI, cold expelling, pain relieving.Be good at and control frequent micturition.
Semen Astragali Complanati: sweet in the mouth, warm in nature, return liver, kidney channel.Temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, improving eyesight.For lumbago due to renal deficiency, seminal emission premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizzy blurred vision.
Semen Cuscutae: sweet in the mouth, warm in nature, return liver,kidney,spleen warp.Nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen, suffer from a deficiency of the kidney and rush down; Externally treating leucoderma.
Semen Plantaginis: sweet in the mouth, cold nature, returns liver, kidney, lung, small intestine meridian.Clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, and improving eyesight is eliminated the phlegm.For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.
Fructus Lycii: sweet in the mouth, warm in nature.There are nourishing kidney Psoralen marrow, nourishing the liver to improve visual acuity and the effect of dispeling the wind.It can yin nourishing, again can invigorating YANG, so clinical, be usually used in the thin disease such as soft of impotence and seminal emission, the waist knee joint of insufficiency of kidney-YANG, also, the liver-yang prosperous disease such as have a dizzy spell cold for kidney yin.
CHUANTAI, Herba Taraxaci eliminating inflammation and expelling toxin in side, Semen Cucurbitae can be prevented and treated prostatosis more effectively, and this 3 medicine is monarch drug; Fructus Alpiniae Oxyphyllae, Semen Astragali Complanati, Fructus Lycii, Semen Cuscutae, Semen Plantaginis, benefiting vital QI for tranquillizing, heat-clearing and toxic substances removing, tonify deficiency replenishing essence, strengthening the body resistance, resisting fatigue, enhancing body immunity, this 5 medicine is ministerial drug; Spina Gleditsiae hard masses softening and resolving, invigorate blood circulation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle; Radix Linderae, Ardisia japonica, Semen Coicis eliminating inflammation and expelling toxin, promoting blood circulation and stopping pain, diuresis, detumescence, this 4 medicine is adjuvant drug.
2. the preparation method of Chinese medicine composition of the present invention, it comprises the steps:
Take respectively by weight above-mentioned raw materials medical material, carried out coarse pulverization, cross 20 mesh sieves, be stirred to mix homogeneously, dry, sterilization and sterilization processing; Mixture after above-mentioned processing is carried out to moistureproof sealed packet and dress up powder or teabag.
3. the dosage form of Chinese medicine composition of the present invention, is characterized by: powder or teabag.
4. the present invention has following effect:
There is clear and definite eliminating inflammation and expelling toxin, tonify deficiency replenishing essence, dampness removing eliminating stagnation, removing blood stasis to promote tissue regeneration, moisturize pain relieving, the effect such as tonifying YIN promotes the production of body fluid, kidney invigorating and YANG supporting, promoting blood circulation to restore menstrual flow, can improve the immunity of body, obviously improve prostatic fluid state, and be conducive to become pregnant; Chinese medicine composition determined curative effect of the present invention, rapid, stable, has no side effect, and is a kind of Chinese medicine health care medicinal for the treatment of male chronic prostatitis.
The specific embodiment
Below by embodiment, the invention will be further described, but not as any restriction to protection domain of the present invention.
1. the composition of embodiment 1-3 and components by weight percent are in Table 1.
2. the EXPERIMENTAL DESIGN of embodiment 1-3 is:
1) be chosen in the Guangxi hospitals of ethnic minority medicine, Guangxi Zhuang hospital, medical chronic prostatitis case 191 examples of the People's Hospital, Chongzuo City, Guangxi andrology.Be divided at random two groups: these name traditional Chinese medicine composition for treating group 148 examples, quinolione group 43 examples.Before and after all case treatments, require respectively to check prostatic fluid routine and prostatic fluid antibacterial culturing (urine three agar diffusion methods).
2) criterion of therapeutical effect is:
Cure: prostatic fluid related index is all normal;
Effective: prostatic fluid related index is clearly better;
Invalid: before and after treatment, above index is unchanged.
3) statistical method: two groups of data relatively adopt t check, χ
2check, P < 0.05 has significant for difference.
3. embodiment 1-3 Chinese medicine composition preparation method:
Get the Chinese medicine composition respective amount of embodiment 1-3, mix, coarse pulverization, crosses 20 mesh sieves, is stirred to mix homogeneously, dries, sterilization and sterilization processing; Mixture after above-mentioned processing is carried out to moistureproof sealed packet and dress up powder or teabag.
4. the Therapeutic Method of embodiment 1-3 is:
Traditional Chinese medicine composition for treating group of the present invention is totally 148 examples, and Therapeutic Method is: embodiment 1 is powder, uses 60 grams of net weight at every turn, and one day three times, minute early, middle and late taking after mixing it with hot water.Embodiment 2 is teabag, uses 80 grams of net weight at every turn, and one day three times, minute early, middle and late decocting 30 minutes of directly using, pour out medicinal liquid, work as tea-drinking.Embodiment 3 is teabag, uses 100 grams at every turn, one day three times, minute early, middle and late directly with boiling water, soak 30 minutes, and pour out medicinal liquid, work as tea-drinking.15 days per courses for the treatment of of embodiment 1-3.
Contrast quinolione treatment group 43 examples: adopt Sparfloxacin in treating, each 200mg, once a day; It within 15 days, is a course for the treatment of.
Drug withdrawal was observed the indexs such as prostatic fluid after 3 days.Viewing duration bans use of any other medicine, does not also adopt other non-drug therapy methods.
5. the result of implementation of embodiment of the present invention 1-3 is in Table 2.
Table 1: Chinese medicine composition composition of the present invention and components by weight percent
Table 2: the present invention is to bacillary and non-bacterial chronic prostatitis Comparison of therapeutic
| Process | Bacillary effective percentage | P value | Non-bacterial effective percentage | P value | Untoward reaction |
| Contrast (quinolione group) | 70.00％(14/20) | ? | 69.57％(16/23) | ? | Have |
| Embodiment 1 | 60.00％(15/25) | ＞0.05 | 89.66％(26/29) | ＜0.05 | Nothing |
| Embodiment 2 | 60.87％(14/23) | ＞0.05 | 88.46％(23/26) | ＜0.05 | Nothing |
| Embodiment 3 | 60.00％(12/20) | ＞0.05 | 88.00％(22/25) | ＜0.05 | Nothing |
Note: respectively organize above case load for carry out the complete case load of reality of urine antibacterial culturing with urine three agar diffusion methods.
Claims (4)
1. a Chinese medicine composition for the treatment of chronic prostatitis, it is characterized in that: in weight portion, comprise CHUANTAI 2-20 part, Rhizoma Acori Graminei 2-20 part, Semen Cucurbitae 2-40 part, Ardisia japonica 2-20 part, Semen Coicis 2-40 part, Herba Taraxaci 2-20 part, Fructus Alpiniae Oxyphyllae 2-40 part, Semen Astragali Complanati 2-20 part, Fructus Lycii 2-20 part, Spina Gleditsiae 2-20 part, Semen Cuscutae 2-20 part, Radix Linderae 2-40 part, Semen Plantaginis 2-40 part.
2. a dosage form for the Chinese medicine composition for the treatment of chronic prostatitis as claimed in claim 1, is characterized in that: its dosage form is powder or teabag.
3. a preparation method for the Chinese medicine composition for the treatment of chronic prostatitis as claimed in claim 1, is characterized in that: the raw medicinal material of Chinese medicine composition is carried out to coarse pulverization, cross 20 mesh sieves, be stirred to mix homogeneously, dry, sterilization and sterilization processing; Mixture after above-mentioned processing is carried out to moistureproof sealed packet and dress up powder or teabag.
4. a Chinese medicine composition for treatment chronic prostatitis as claimed in claim 1, is characterized in that: have the immunity of organisms of raising, improve prostatic fluid state, reach the effect for the treatment of chronic prostatitis.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106474410A (en) * | 2016-12-28 | 2017-03-08 | 陕西红顶名医堂药业有限公司 | For treating Chinese medicine composition of chronic prostatitiss and preparation method thereof |
| CN113679776A (en) * | 2021-09-14 | 2021-11-23 | 北京居正堂健康科技有限责任公司 | Composition for treating prostatitis and preparation method and preparation thereof |
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| CN103599477A (en) * | 2013-11-14 | 2014-02-26 | 济川药业集团股份有限公司 | Traditional Chinese medicinal composition for treating humid heat stagnation type chronic prostatitis |
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Patent Citations (2)
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| CN102145146A (en) * | 2007-09-13 | 2011-08-10 | 北京亚东生物制药有限公司 | Method for detecting medicinal composition for treating urinary system diseases |
| CN103599477A (en) * | 2013-11-14 | 2014-02-26 | 济川药业集团股份有限公司 | Traditional Chinese medicinal composition for treating humid heat stagnation type chronic prostatitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106474410A (en) * | 2016-12-28 | 2017-03-08 | 陕西红顶名医堂药业有限公司 | For treating Chinese medicine composition of chronic prostatitiss and preparation method thereof |
| CN113679776A (en) * | 2021-09-14 | 2021-11-23 | 北京居正堂健康科技有限责任公司 | Composition for treating prostatitis and preparation method and preparation thereof |
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Application publication date: 20140910 |