CN104857424A - Medicine for treating thick blood lipid and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating thick blood lipid and a preparation method thereof. An appropriate quantity of rhizoma alismatis, radix curcuma, radix bupleuri, honeysuckle, panax notoginseng, codonopsis pilosula, seabuckthorn, lumbricus, glossy privet fruit, trogopterus dung, radix polygonati officinalis, prepared fleeceflower roots, rhizoma sparganii, lotus leaves and the like can be selected to be combined, famous and precious herbs are absent among the selected ingredients, costs are low, the medicine efficacy is good, the effects of the combined herbs include synergistic effect, functions of clearing heat, cooling blood, dispersing blood stasis, invigorating blood circulation and promoting the circulation of qi can be achieved, thick blood lipid is effectively cured, and the ideal effect of treating both symptoms and root causes can be achieved. A processing method of the medicine is relatively simple, and the processed medicine is convenient to take and carry about.

Description

A kind of medicine for the treatment of thick blood fat and preparation method thereof

Technical field

The present invention relates to medical art, specifically a kind of medicine for the treatment of thick blood fat and preparation method thereof.

Background technology

Thick blood fat refers to the triglyceride existed in the middle of blood, the impurity such as cholesterol are higher, its principal pathogenetic mechanism is that Sheng crossed by conscience fire, stagnation of QI due to depression of the liver, its clinical manifestation is hyperlipidemia, QI and blood is not smooth, symptom is mainly and shows the following aspects: general symptom shows as more: dizzy, spiritlessness and weakness, insomnia forgetfulness, numb limbs and tense tendons, breast is vexed, cardiopalmus etc., there will be time more serious and have a dizzy spell, headache, breast is vexed, breathe hard, nervous, chest pain, weak, distortion of commissure, mute, the symptoms such as numb limbs and tense tendons, finally coronary heart disease can be caused, the multiple serious disease such as apoplexy.

Current Western medicine lipid lowerers mainly contains two large classes, to reduce T-CHOL and low density lipoprotein, LDL for main first-elected Statins, comprises lovastatin, simvastatin, pravastatin etc.Reducing triglyceride is main person with the special class of shellfish for representative, as fenofibrate, lifibrate, ciprofibrate and clofibrate etc.

The blood fat reducing mechanism of Western medicine: by blocking lipogenesis, or reduce fat the object of the blood fat reducing reached.

Research finds, Western medicine blood fat reducing has the side effect of the following aspects: blood creatine phosphokinase (CPK) content 1, can be made obviously to raise, there is the myolysis of muscular soreness or muscle weakness phenomenon, myolysis is a kind of very serious myopathy, the muscular tissue of patient is damaged, and discharges a large amount of Myoglobin.2, Myoglobin excretes through kidney, makes urine become Umber, under serious conditions, acute renal failure can be caused even dead.3, blood fat reducing Western medicine is mainly regulated by liver the shunting of blood fat and adjustment, blindly takes blood fat reducing Western medicine over a long time, can increase the weight of burden of liver, make fat generation aggravation in hepatocyte, liver enlargement, blood glutamate pyruvate transaminase raises, and some patients also can occur jaundice.4, can only take stopgap measures and can not effect a permanent cure, Western medicine blood fat reducing is inreal solves human body production hyperliposis, utilize the real cause of disease that fat is not enough, some patient is caused to take medicine all the life, stand hardship that is nauseating, the huge side effect murder by poisoning such as abdominal distention, diarrhoea and liver function injury all the life, bring huge economic loss and stress to this type of condition subject.

Summary of the invention

The technical problem to be solved in the present invention is to provide a kind of medicine for the treatment of thick blood fat and preparation method thereof, the Rhizoma Alismatis that this medicament selection is appropriate; Rhizoma Curcumae Longae; Radix Bupleuri; Flos Lonicerae; Radix Notoginseng; Radix Codonopsis; Fructus Hippophae; Pheretima; Fructus Ligustri Lucidi; Oletum Trogopterori; Rhizoma Polygonati Odorati; Radix Polygoni Multiflori Preparata; Rhizoma Sparganii; Folium Nelumbinis etc. carry out combination and compatibility, and selected component is without famous and precious medicine, and cost is low, good drug efficacy, and make the effect after compatibility of drugs produce synergism, there is heat clearing away, removing heat from blood, dissipating blood stasis, invigorate blood circulation, circulation of qi promoting, effective treatment thick blood fat, can reach the ideal effect for the treatment of both the principal and secondary aspects of a disease.

For solving the problems of the technologies described above, a kind of medicine for the treatment of thick blood fat of the present invention, the component of this medicine is counted by weight: Rhizoma Alismatis 8 ~ 11 parts; 6 ~ 8 parts, Rhizoma Curcumae Longae; Radix Bupleuri 4 ~ 6 parts; Flos Lonicerae 4 ~ 6 parts; Radix Notoginseng 5 ~ 10 parts; Radix Codonopsis 8 ~ 10 parts; Fructus Hippophae 5 ~ 7 parts; Pheretima 6 ~ 8 parts; Fructus Ligustri Lucidi 8-11 part; Oletum Trogopterori 6 ~ 7 parts; Rhizoma Polygonati Odorati 8 ~ 10 parts; Radix Polygoni Multiflori Preparata 8 ~ 13 parts; Rhizoma Sparganii 7 ~ 8 parts; 5 ~ 7 parts, Folium Nelumbinis.

As the further improvement to the technical program, the component of this medicine is counted by weight: the component of this medicine is counted by weight: Rhizoma Alismatis 9 parts; 7 parts, Rhizoma Curcumae Longae; Radix Bupleuri 5 parts; Flos Lonicerae 5 parts; Radix Notoginseng 8 parts; Radix Codonopsis 9 parts; Fructus Hippophae 6 parts; Pheretima 7 parts; Fructus Ligustri Lucidi 10 parts; Oletum Trogopterori 7 parts; Rhizoma Polygonati Odorati 9 parts; Radix Polygoni Multiflori Preparata 10 parts; Rhizoma Sparganii 8 parts; 6 parts, Folium Nelumbinis.

As the further improvement to the technical program, the component of this medicine is counted by weight: the component of this medicine is counted by weight: Rhizoma Alismatis 11 parts; 8 parts, Rhizoma Curcumae Longae; Radix Bupleuri 4 parts; Flos Lonicerae 4 parts; Radix Notoginseng 10 parts; Radix Codonopsis 10 parts; Fructus Hippophae 5 parts; Pheretima 8 parts; Fructus Ligustri Lucidi 11 parts; Oletum Trogopterori 6 parts; Rhizoma Polygonati Odorati 8 parts; Radix Polygoni Multiflori Preparata 13 parts; Rhizoma Sparganii 7 parts; 7 parts, Folium Nelumbinis.

Technical scheme of the present invention, the composite pharmacological action of medicine is as follows:

Rhizoma Alismatis, sweet, cold.Return kidney, urinary bladder channel; Diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, expectorant is dizzy by the emperor himself, the puckery pain of pyretic stranguria; Hyperlipidemia.

Select Rhizoma Alismatis, active ingredient triterpenoid compound contained by it, the absorption of exogenous cholesterol and triacylglycerol can be suppressed, accelerate the hydrolysis of triacylglycerol, promote the removing of arterial wall normal cholesterol and be transported to liver metabolism and excretion, there are obvious cholesterol reducing, anti thrombotic action and study of anti-atherogenic effect, therefore blood fat, blood pressure can be reduced; Diuresis, clearing away damp-heat.

Rhizoma Curcumae Longae, pungent, bitter, temperature.Return spleen, Liver Channel.Removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.Twinge for the breast side of body, amenorrhea, addiction abdominal mass, rheumatism shoulder arm pain, tumbling and swelling.

The effect of total plasma cholesterol and B-lipoprotein, falls in the curcumol that Rhizoma Curcumae Longae contains, curcumin and volatilization wet goods, and can reduce liver cholesterol; Rhizoma Curcumae Longae can also increase fibrinous lytic activity, has antithrombotic effect, has significant therapeutic effect to hyperlipidemia.Curcumin, volatile oil, turmerone and zingiberene, Borneolum Syntheticum and sesquiterpenoid etc., have choleretic effect, promotes gallbladder contraction, increases generation and the secretion of bile.In bile, most important composition cholate has the effect of the absorption and digestion promoting fat.Curcumin has a significant effect to platelet aggregation and blood viscosity, and platelet aggregation can be made to weaken, and plasma viscosity and whole blood viscosity reduce, and increase cardiac muscle nutritional blood flow.

Radix Bupleuri, bitter, be slightly cold.Return liver, gallbladder meridian.Reconciling superficies and interior, soothing the liver, yang invigorating.Cholesterol reducing effect can be had.

Flos Lonicerae, sweet, cold.Return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.Enteral cholesterol absorption can be reduced, reduce cholesterol level in blood plasma.

Radix Notoginseng, sweet, micro-hardship, temperature.Return liver, stomach warp.Can stop blooding by dissipating blood stasis, subduing swelling and relieving pain.For spitting of blood, spit blood, have blood in stool, metrorrhagia, breast ventral spine pain, tumbling and swelling.

Select Radix Notoginseng, it have invigorating blood circulation, stop blooding, enrich blood, antithrombotic function.Radix Notoginseng total arasaponins is increased significantly the total saponins of leukocytic effect contained by Radix Notoginseng and has good myocardium protecting action; can heart tonifying and blood vessel dilating; strengthen coronary artery blood flow; reduce arterial pressure; the formation of atheromatous plaque and short its can be prevented to disappear, improve blood viscosity, reduce blood fat and serum cholesterol; especially the content of triglyceride can be reduced significantly; reduce cardiovascular and cerebrovascular vessel thrombosis, to thick blood fat and arteriosclerosis, coronary heart disease, hypertension, diabetes and other diseases, there is good effect.

Radix Codonopsis is sweet, flat.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.

Select Radix Codonopsis, it has invigorating middle warmer, QI invigorating, and the effect of promoting the production of body fluid, has excitation to nervous system, and energy enhancing body resistance, expansion peripheral vessels reduces blood pressure, and strengthens hemopoietic function, regulates blood pressure, resists myocardial ischemia and anticoagulant.

Fructus Hippophae, sour, puckery, warm.Eliminating phlegm and stopping cough, relieving dyspepsia, promoting blood circulation to remove blood stasis.For cough with copious phlegm, dyspepsia, abdominal pain due to retention of food, falls and flutters congestive edema, blood stasis amenorrhea.

Select Fructus Hippophae, can promoting blood circulation to remove blood stasis be played in the present invention, have the effect of falling and subtracting plasma cholesterol, reducing cholesterol level in blood vessel wall, can anti-curing hyperlipemia and atherosclerosis.

Pheretima is salty, cold.Return liver, spleen, urinary bladder channel.Heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.

Select Pheretima, it can coordinate with other drug component and plays thrombus, vessel softening, reduction blood viscosity, regulates effect of blood pressure blood fat.Fresh and the old thrombosis of fibrinolysin contained by Pheretima, activator of plasminogen and collagenase solubilized, active earthworm protein can reduce erythrocyte and leukocytic adhesion, thus reduces blood viscosity; In addition, Pheretima can also improve systemic microcirculation, allows the blood capillary of sclerosis recover elasticity.

Fructus Ligustri Lucidi, sweet, bitter, cold.Return liver, kidney channel.Nourishing the liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.

Select Fructus Ligustri Lucidi, serum ornitrol and content of triglyceride can be reduced, and make aorta Lipid Plaque and Atherosclerotic Vessels: Changes Observed during Coronary form abatement, obviously reduce the total cholesterol of serum, lipid peroxide, the total cholesterol content of arterial wall, reduce atherosclerotic incidence rate.

Oletum Trogopterori, salty, sweet, temperature, return Liver Channel, nontoxic.Invigorate blood circulation, language, pain relieving, for breast the side of body, chamber ventral spine pain, dysmenorrhea, amenorrhea, puerperal blood stasis pain, tumbling and swelling, snake bite and insect sting.

Select Oletum Trogopterori, it can make blood flow volume increase, and vascular resistance reduces, and has dredging blood vessel, effect of eliminating stasis to stop pain.

Rhizoma Polygonati Odorati, sweet, be slightly cold.Attach to the lung and stomach meridians.Nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.For lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.

Select Rhizoma Polygonati Odorati, its sweet in the mouth, greasiness, soft and moist edible, be longer than yin nourishing, mend and oiliness, cold not dry, have the merit of " tonification the five internal organs, nourish QI and blood, flat benefit and moistening, and hold concurrently except wind heat ", the triglyceride in human body, cholesterolemia and B-lipoprotein can be made to decline.

Radix Polygoni Multiflori Preparata, bitter, sweet, puckery, temperature, return liver, the heart, kidney channel.Invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening.For blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body is empty; Hyperlipidemia.

Select Radix Polygoni Multiflori Preparata, it has the effects such as invigorating the liver and kidney, benefiting essence-blood, bone and muscle strengthening, the turbid blood fat reducing of change in the present invention, can expand the coronary artery of heart, blood fat reducing, promote erythrocytic generation, have good treatment and preventive effect to coronary heart disease, hyperlipidemia etc.Radix Polygoni Multiflori Preparata can promote the wriggling of intestinal, reduces lipid in the intestinal time of staying, reduces the absorption at intestinal of triacylglycerol and cholesterol.

Rhizoma Sparganii is pungent, bitter, flat.Return liver, spleen channel.Removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving, lump in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.

Select Rhizoma Sparganii, its in the present invention can anticoagulant, the effect that extends thrombus formation time, shorten thrombosis length and weight reduction, also have the trend extending prothrombin time and part Thrombokinase, reduce whole blood viscosity.

Folium Nelumbinis is bitter, flat.Return liver, spleen, stomach warp.Clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood, metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding.For multiple hemorrhage and puerperal blood faints.Folium Nelumbinis, and enter liver more and divide, flat heat, dries, and with row clearing heat in QI system, enters liver also with green grass or young crops.The taste of right bitterness, real with removing pathogen in the heart liver clearing heat in the lung solid water, therefore can blood stasis removing, protect essence, except absurd heat, flat QI and blood also.

Select Folium Nelumbinis, it has clearing away heart-fire, suppressing the hyperactive liver fire, purgation of spleen excess is fiery, fall lung-fire and heat clearing away is reposed, antihypertensive diuretic, hold back liquid hidroschesis, the controlling nocturnal emission with astringent drugs that stops blooding, change and turbidly go the effects such as greasy, liver nourishing lung moistening, contained aromatic compound can effective dissolved fat, prevents fat from stagnating; The expansible blood vessel of Folium Nelumbinis, clearing away summer-heat; Triglyceride and cholesterol level in blood pressure lowering, reduction serum, adjusting blood lipid, and the antihypertensive diuretic of Folium Nelumbinis can reduce the side effect that drug administration is produced; Folium Nelumbinis can make intestinal form a skim, stops lipid to enter small intestinal mucosa cell, reduces the absorption of lipid.

The said medicine of the technical program, according to treatment by Chinese herbs principle, in conjunction with clinical experience for many years, selected multiple prepared from traditional Chinese medicines forms, and can regulate human liver, spleen, stomach, spleen, the heart, kidney energy internal organs comprehensively, Yin Yang balancing reaches heat clearing away, removing heat from blood, dissipating blood stasis, invigorates blood circulation, circulation of qi promoting, effectively can reduce blood pressure and cholesterol, softening blood vessel dilating, increase blood flow, enhancing body resistance, thus effectively treat thick blood fat, reach the ideal effect for the treatment of both the principal and secondary aspects of a disease.

Treat a medicine for thick blood fat, its preparation process comprises following steps:

(1) after Rhizoma Alismatis, Radix Bupleuri cleaning, stir-fry 2-4 time separately in 80 ~ 90 DEG C of hot pots, by yellow wine spray Rhizoma Alismatis sheet, radix bupleuri tablet in the process that stir-fries, the amount ratio of Rhizoma Alismatis and yellow wine is 18: 1; The amount ratio of Radix Bupleuri and yellow wine is 10: 1; By Rhizoma Alismatis, Radix Bupleuri fried dry, grind as powder respectively after spray;

(2) Oletum Trogopterori, cleaning, except sandstone impurity, is heated in 70-75 DEG C of hot pot, spray yellow wine, and Oletum Trogopterori and yellow wine amount ratio are 7: 1, sprays rear fried dry, grinds as powder;

(3) Rhizoma Sparganii section, mixes thoroughly with vinegar, runs through, and puts in pot to fry to complexion changed dark, takes out, cools.Rhizoma Sparganii and vinegar amount ratio are 40: 1;

(4) Rhizoma Curcumae Longae, Flos Lonicerae, Radix Notoginseng, Radix Codonopsis, Fructus Hippophae, Pheretima, Fructus Ligustri Lucidi, Rhizoma Polygonati Odorati, Radix Polygoni Multiflori Preparata, Folium Nelumbinis, separately screen cleaning, pulverize, at 50 ~ 60 DEG C dry, grind separately as powder;

(5) above-mentioned powder mix homogeneously, crosses 100 mesh sieves; Incapsulate by 0.5 gram/or 1 gram of/amount.

The processing and concocting method of this medicine is relatively simple, and the medicine after processing carries, taking convenience.

Rhizoma Alismatis in herbal component described in the technical program, Oletum Trogopterori, through cleaning, being removed impurity, through roasting, effectively can reduce the toxicity of this medicine; Roast in process and spray yellow wine, the active ingredient in medicine can be allowed to retain, simultaneously, various trace elements contained in yellow wine and medicine fuse, enhance medicine heat clearing away, removing heat from blood, dissipating blood stasis, invigorate blood circulation, the effect of circulation of qi promoting, medicine is reduced blood pressure and cholesterol, softening blood vessel dilating, increase blood flow, the effect of enhancing body resistance is stronger.Other components of this medicine, through cleaning and oven dry, can remove the impurity contained by medicine, reduce the impact on the medicine property of medicine.

The technical program compared with prior art, has following beneficial effect:

(1) compared with other Chinese medicines of the prior art, this technology have employed distinct combined traditional Chinese medicine completely, and it is simple that selected component has component, and not containing famous and precious medicine, material easily obtains and low price, and thus cost is low.

(2) active ingredient of Radix Polygoni Multiflori Preparata of the present invention and other component combineds effect can make human body reduce the absorption of cholesterol, thus suppress the absorption of exogenous lipid; Rhizoma Alismatis, active ingredient triterpenoid compound contained by it, the absorption of exogenous cholesterol and triacylglycerol can be suppressed, accelerate the hydrolysis of triacylglycerol, promote the removing of arterial wall normal cholesterol and be transported to liver metabolism and excretion, there are obvious cholesterol reducing, anti thrombotic action and study of anti-atherogenic effect, therefore blood fat, blood pressure can be reduced; Diuresis, clearing away damp-heat; Pheretima, it can coordinate with other drug component and plays thrombus, vessel softening, reduction blood viscosity, regulates effect of blood pressure blood fat.Fresh and the old thrombosis of fibrinolysin contained by Pheretima, activator of plasminogen and collagenase solubilized, active earthworm protein can reduce erythrocyte and leukocytic adhesion, thus reduces blood viscosity; In addition, Pheretima can also improve systemic microcirculation, allows the blood capillary of sclerosis recover elasticity.

After the selected Chinese medicinal material compatibility of the technical program, heat clearing away, removing heat from blood, dissipating blood stasis that pharmaceutical compositions has can be given full play to, invigorate blood circulation, circulation of qi promoting effect, promote lipid transfer and excretion, adjustment lipid metabolism by the absorption, the effect that reduce lipid, effectively treat thick blood fat comprehensively.

This programme clinical application effect is good, and its therapeutic effect situation is as follows:

1, clinical case situation: we, in the clinical practice of Donga County institute of traditional Chinese medicine, in a year of statistics in January, 2014-December, treat thick blood fat patient 353 people altogether; Mean age 56; Wherein, medical history is case 246 people of 1-3, the medical history case of more than 3 years 107 people.

2, efficacy assessment standard:

(1) cure, clinical symptom disappearance, and to cure in latter 1 year non-recidivist for curing.

(2) effective, the state of an illness is clearly better, and dizziness, headache, the symptom such as unable alleviate or disappear, and cholesterol, triglyceride reduce.

(3) invalid, after treatment, symptom is unchanged.

3, Therapeutic Method: medical history is case 246 people of 1-3, takes 3 courses for the treatment of of this prescription, 2 months 1 courses for the treatment of, 6 totally months; The medical history case of more than 3 years 107 people, treats 4-6 the course for the treatment of of the course for the treatment of.Treatment consumption: adult every day three times, 1 gram every, each 1 ~ 3.

4, therapeutic outcome: cure 293 people's (clinical symptom disappearance, and to cure in latter 1 year non-recidivist for curing), effective case 46 people (state of an illness is clearly better), Ineffective Cases 14 people (after treatment, symptom is unchanged), cure rate is 83%, and effective percentage is 96%.

Detailed description of the invention

Embodiment 1

Treat a medicine for thick blood fat, the component of this medicine is counted by weight: Rhizoma Alismatis 9 parts; 7 parts, Rhizoma Curcumae Longae; Radix Bupleuri 5 parts; Flos Lonicerae 5 parts; Radix Notoginseng 8 parts; Radix Codonopsis 9 parts; Fructus Hippophae 6 parts; Pheretima 7 parts; Fructus Ligustri Lucidi 10 parts; Oletum Trogopterori 7 parts; Rhizoma Polygonati Odorati 9 parts; Radix Polygoni Multiflori Preparata 10 parts; Rhizoma Sparganii 8 parts; 6 parts, Folium Nelumbinis.

Embodiment 2

Treat a medicine for thick blood fat, the component of this medicine is counted by weight: Rhizoma Alismatis 11 parts; 8 parts, Rhizoma Curcumae Longae; Radix Bupleuri 4 parts; Flos Lonicerae 4 parts; Radix Notoginseng 10 parts; Radix Codonopsis 10 parts; Fructus Hippophae 5 parts; Pheretima 8 parts; Fructus Ligustri Lucidi 11 parts; Oletum Trogopterori 6 parts; Rhizoma Polygonati Odorati 8 parts; Radix Polygoni Multiflori Preparata 13 parts; Rhizoma Sparganii 7 parts; 7 parts, Folium Nelumbinis.

Treat a medicine for thick blood fat, its preparation process comprises following steps:

(1) after Rhizoma Alismatis, Radix Bupleuri cleaning, stir-fry 2-4 time separately in 80 ~ 90 DEG C of hot pots, by yellow wine spray Rhizoma Alismatis sheet, radix bupleuri tablet in the process that stir-fries, the amount ratio of Rhizoma Alismatis and yellow wine is 18: 1; The amount ratio of Radix Bupleuri and yellow wine is 10: 1; By Rhizoma Alismatis, Radix Bupleuri fried dry, grind as powder respectively after spray;

(2) Oletum Trogopterori, cleaning, except sandstone impurity, is heated in 70-75 DEG C of hot pot, spray yellow wine, and Oletum Trogopterori and yellow wine amount ratio are 7: 1, sprays rear fried dry, grinds as powder;

(3) Rhizoma Sparganii section, mixes thoroughly with vinegar, runs through, and puts in pot to fry to complexion changed dark, takes out, cools.Rhizoma Sparganii and vinegar amount ratio are 40: 1;

(4) Rhizoma Curcumae Longae, Flos Lonicerae, Radix Notoginseng, Radix Codonopsis, Fructus Hippophae, Pheretima, Fructus Ligustri Lucidi, Rhizoma Polygonati Odorati, Radix Polygoni Multiflori Preparata, Folium Nelumbinis, separately screen cleaning, pulverize, at 50 ~ 60 DEG C dry, grind separately as powder;

(5) above-mentioned powder mix homogeneously, crosses 100 mesh sieves; Incapsulate by 0.5 gram/or 1 gram of/amount.

The said medicine of the technical program, be according to treatment by Chinese herbs principle, in conjunction with clinical experience for many years, selected multiple prepared from traditional Chinese medicines forms, active ingredient and other component combineds effect of Radix Polygoni Multiflori Preparata of the present invention can make human body reduce the absorption of cholesterol, thus suppress the absorption of exogenous lipid; Rhizoma Alismatis, active ingredient triterpenoid compound contained by it, the absorption of exogenous cholesterol and triacylglycerol can be suppressed, accelerate the hydrolysis of triacylglycerol, promote the removing of arterial wall normal cholesterol and be transported to liver metabolism and excretion, there are obvious cholesterol reducing, anti thrombotic action and study of anti-atherogenic effect, therefore blood fat, blood pressure can be reduced; Diuresis, clearing away damp-heat; Pheretima, it can coordinate with other drug component and plays thrombus, vessel softening, reduction blood viscosity, regulates effect of blood pressure blood fat.Fresh and the old thrombosis of fibrinolysin contained by Pheretima, activator of plasminogen and collagenase solubilized, active earthworm protein can reduce erythrocyte and leukocytic adhesion, thus reduces blood viscosity; In addition, Pheretima can also improve systemic microcirculation, allows the blood capillary of sclerosis recover elasticity.And with under other drug mating reaction, human liver, spleen, stomach, spleen, the heart, kidney energy internal organs can be regulated comprehensively, Yin Yang balancing reaches heat clearing away, removing heat from blood, dissipating blood stasis, invigorates blood circulation, circulation of qi promoting, can effectively reduce blood pressure and cholesterol, softening blood vessel dilating, increase blood flow, enhancing body resistance, thus effectively treat thick blood fat, reach the ideal effect for the treatment of both the principal and secondary aspects of a disease.

The scheme of this medicine specific embodiment 1, is applied to clinical, and the model case for the treatment of is as follows:

1, king so-and-so, man, 61 years old, Donga County, Shandong Province king sea villager, suffers from thick blood fat sick 1 year.Take simvastatin day 1, visit aspirin day 1.Cholesterol 5.76, has headache, dizziness, takes thick blood fat capsule of the present invention, every day three times, 1 gram every, each 2.After 2 months course for the treatment of, rear headache, dizziness disappear.Cholesterol drops to 4.52, and after taking two drug withdrawals course for the treatment of, result of laboratory test is within normal range.

2, Zhang, man, 54 years old, sick 2 years of Liao Cheng city of Shandong Province bridge town resident, trouble thick blood fat, now took simvastatin day 2.Visit aspirin day 1, rush blood vessel 1 year 2 ~ 3 times.Cholesterol 6.41, triglyceride 2.79, takes thick blood fat capsule of the present invention, every day three times, 1 gram every, each 2.After 4 months, take Western medicine and respectively subtract half.Cholesterol drops to 5.32, and triglyceride drops to 1.58.Take thick blood fat capsule of the present invention 6 months, Western medicine, rush blood vessel and no longer use.Cholesterol drops to 4.92, and triglyceride drops to 1.47, and after drug withdrawal, 6 months results of laboratory test are normal.

3, Liu so-and-so, female 57 years old, Donga County, Shandong Province Liu cheats villager, suffers from thick blood fat sick 2 years, takes simvastatin day 2.Triglyceride 6.03, takes thick blood fat capsule of the present invention, every day three times, 1 gram every, each 2.After 4 months, Western medicine is stopped using, and triglyceride drops to 2.24, and take thick blood fat capsule of the present invention 6 months, triglyceride drops to 1.72, checks normal after drug withdrawal.

4, king so-and-so, female, 59 years old, Pingying County Flos Rosae Rugosae town, Shandong Province resident, suffered from thick blood fat sick 3 years, takes Western medicine all the year round, cholesterol 5.62, triglyceride 3.82.There is dizziness, numbness of hand, the symptom such as unable, take thick blood fat capsule of the present invention, every day three times, 1 gram every, each 3.4 months, cholesterol dropped to 5.13, triglyceride drops to 3.24, dizzyly waited transference cure.Take thick blood fat capsule of the present invention 6 months, Western medicine is stopped using, and cholesterol drops to 4.92, and triglyceride drops to 2.62.Take thick blood fat capsule of the present invention 8 months, cholesterol falls 4.74 triglyceride and drops to 1.63 drug withdrawals.Drug withdrawal cholesterol after 10 months, triglyceride result of laboratory test are normal.

5, grandson so-and-so, man, 66 years old, Chiping County, Liaocheng of Shandong Province Korea Spro collected the rural people, suffered from thick blood fat sick 10 years, took simvastatin day 2 all the year round.Visit aspirin day 1, rush blood vessel 1 year 3 to 4 times, cholesterol 6.20, triglyceride 6.80, occur unable, headache, dizziness, foot numbness of hand wood.Take thick blood fat capsule of the present invention, every day three times, 1 gram every, each 3.After the course for the treatment of, weak, headache, dizziness, disappear.Take thick blood fat capsule of the present invention two the cholesterol course for the treatment of and drop to 5.78, triglyceride drops to 3.67, and take thick blood fat capsule of the present invention four the foot numbness of hand wood course for the treatment of and disappear, cholesterol drops to 5.31, and triglyceride drops to 1.52.After taking thick blood fat capsule of the present invention, five courses for the treatment of stablize, and drug withdrawal 8 months results of laboratory test are in normally.

6, Lee so-and-so, female 52 years old, rural area, Niu Dian town, Donga County, the Shandong Province people, suffers from thick blood fat, hypertension 6 years, take polysaccharide sulfate day 1 all the year round, visit aspirin day 1, simvastatin day 1, nimodipine day 2, flunarizine day 1, clinical manifestation has the symptoms such as headache, unable, foot numbness of hand is wooden.Triglyceride 2.9, takes thick blood fat capsule of the present invention, every day three times, 1 gram every, each 3.After the course for the treatment of, Western medicine respectively reduces by half, and headache after taking two courses for the treatment of of thick blood fat capsule of the present invention, unable, foot numbness of hand wood disappear.Triglyceride drops to 2.2, and after taking three courses for the treatment of of thick blood fat capsule of the present invention, triglyceride drops to 1.42, and after taking five courses for the treatment of of thick blood fat capsule of the present invention, Western medicine is no longer used.Normal after taking six courses for the treatment of of thick blood fat capsule of the present invention, drug withdrawal is stablized half a year.

7, Lee so-and-so, female, land for growing field crops, Gaotang County, 62 years old Shandong Province community resident, suffers from that thick blood fat is sick, hypertension 7 years, takes simvastatin day 2 all the year round, visits aspirin day 1.Rush blood vessel every year 2 ~ 4 times.Result of laboratory test triglyceride 3.68, has dizziness, headache, the symptom such as unable, takes two courses for the treatment of of thick blood fat capsule of the present invention, four totally months, every day three times, 1 gram every, each 3.Dizzy wait transference cure, triglyceride drops to 2.10, and take two courses for the treatment of of thick blood fat capsule of the present invention, simvastatin is day 1, visits aspirin day 0.5, and triglyceride drops to 1.82.Take three courses for the treatment of of thick blood fat capsule of the present invention, triglyceride drops to 1.72.Do not taking Western medicine.Take four courses for the treatment of of thick blood fat capsule of the present invention, triglyceride is stablized.Take thick blood fat capsule of the present invention five drug withdrawals course for the treatment of.After August, triglyceride result of laboratory test is 1.43.

8, Liu so-and-so, man, 67 years old, rural area, Rhizoma Zingiberis Recens building, Donga County, the Shandong Province people, to suffer from thick blood fat sick, and hypertension 15 years, takes KADUOPULI day 2, simvastatin day 2, takes polysaccharide sulfate day 1, visits aspirin day 1.There is headache, unable, foot numbness of hand wood.Cholesterol 6.32, triglyceride 3.47, takes thick blood fat capsule of the present invention, every day three times, 1 gram every, each 3.Take headache after a course for the treatment of, weak, disappear.Take two rear foot numbness of hand wood disappearances course for the treatment of.Western medicine respectively reduces by half, and after taking four courses for the treatment of of thick blood fat capsule of the present invention, Western medicine is no longer used.Cholesterol drops to 3.90, and triglyceride drops to 0.80, and take stable disease after six courses for the treatment of of thick blood fat capsule of the present invention, drug withdrawal result of laboratory test is normal.

The medicine of the technical program, according to treatment by Chinese herbs principle, in conjunction with clinical experience for many years, selected multiple prepared from traditional Chinese medicines forms, and human liver can be regulated comprehensively, spleen, stomach, spleen, the heart, kidney energy internal organs, Yin Yang balancing reaches heat clearing away, removing heat from blood, dissipating blood stasis, invigorate blood circulation, circulation of qi promoting, can effectively reduce blood pressure and cholesterol, softening blood vessel dilating, increase blood flow, enhancing body resistance, thus effectively treat thick blood fat, reach the ideal effect for the treatment of both the principal and secondary aspects of a disease, there is good drug efficacy, toxic and side effects is low, effective treatment thick blood fat, reach the ideal effect for the treatment of both the principal and secondary aspects of a disease.

Claims (4)

1. treat a medicine for thick blood fat, it is characterized in that, the component of this medicine is counted by weight: Rhizoma Alismatis 8 ~ 11 parts; 6 ~ 8 parts, Rhizoma Curcumae Longae; Radix Bupleuri 4 ~ 6 parts; Flos Lonicerae 4 ~ 6 parts; Radix Notoginseng 5 ~ 10 parts; Radix Codonopsis 8 ~ 10 parts; Fructus Hippophae 5 ~ 7 parts; Pheretima 6 ~ 8 parts; Fructus Ligustri Lucidi 8-11 part; Oletum Trogopterori 6 ~ 7 parts; Rhizoma Polygonati Odorati 8 ~ 10 parts; Radix Polygoni Multiflori Preparata 8 ~ 13 parts; Rhizoma Sparganii 7 ~ 8 parts; 5 ~ 7 parts, Folium Nelumbinis.

2. a kind of medicine for the treatment of thick blood fat according to claim 1, is characterized in that: the component of this medicine is counted by weight: Rhizoma Alismatis 9 parts; 7 parts, Rhizoma Curcumae Longae; Radix Bupleuri 5 parts; Flos Lonicerae 5 parts; Radix Notoginseng 8 parts; Radix Codonopsis 9 parts; Fructus Hippophae 6 parts; Pheretima 7 parts; Fructus Ligustri Lucidi 10 parts; Oletum Trogopterori 7 parts; Rhizoma Polygonati Odorati 9 parts; Radix Polygoni Multiflori Preparata 10 parts; Rhizoma Sparganii 8 parts; 6 parts, Folium Nelumbinis.

3. a kind of medicine for the treatment of thick blood fat according to claim 1, is characterized in that: the component of this medicine is counted by weight: Rhizoma Alismatis 11 parts; 8 parts, Rhizoma Curcumae Longae; Radix Bupleuri 4 parts; Flos Lonicerae 4 parts; Radix Notoginseng 10 parts; Radix Codonopsis 10 parts; Fructus Hippophae 5 parts; Pheretima 8 parts; Fructus Ligustri Lucidi 11 parts; Oletum Trogopterori 6 parts; Rhizoma Polygonati Odorati 8 parts; Radix Polygoni Multiflori Preparata 13 parts; Rhizoma Sparganii 7 parts; 7 parts, Folium Nelumbinis.

4. a kind of medicine for the treatment of thick blood fat according to claim 1-3 any one claim, is characterized in that preparation process comprises following steps:

(1) after Rhizoma Alismatis, Radix Bupleuri cleaning, stir-fry 2-4 time separately in 80 ~ 90 DEG C of hot pots, by yellow wine spray Rhizoma Alismatis sheet, radix bupleuri tablet in the process that stir-fries, the amount ratio of Rhizoma Alismatis and yellow wine is 18: 1; The amount ratio of Radix Bupleuri and yellow wine is 10: 1; By Rhizoma Alismatis, Radix Bupleuri fried dry, grind as powder respectively after spray;

(2) Oletum Trogopterori, cleaning, except sandstone impurity, is heated in 70-75 DEG C of hot pot, spray yellow wine, and Oletum Trogopterori and yellow wine amount ratio are 7: 1, sprays rear fried dry, grinds as powder;

(3) Rhizoma Sparganii section, mixes thoroughly with vinegar, runs through, and puts in pot to fry to complexion changed dark, takes out, cools.Rhizoma Sparganii and vinegar amount ratio are 40: 1;

(4) Rhizoma Curcumae Longae, Flos Lonicerae, Radix Notoginseng, Radix Codonopsis, Fructus Hippophae, Pheretima, Fructus Ligustri Lucidi, Rhizoma Polygonati Odorati, Radix Polygoni Multiflori Preparata, Folium Nelumbinis, separately screen cleaning, pulverize, at 50 ~ 60 DEG C dry, grind separately as powder;

(5) above-mentioned powder mix homogeneously, crosses 100 mesh sieves; Incapsulate according to quantity.