CN104857196A - Traditional Chinese medicine preparation for treating epidural anesthesia nerve injuries - Google Patents

Traditional Chinese medicine preparation for treating epidural anesthesia nerve injuries Download PDF

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CN104857196A
CN104857196A CN201510315398.2A CN201510315398A CN104857196A CN 104857196 A CN104857196 A CN 104857196A CN 201510315398 A CN201510315398 A CN 201510315398A CN 104857196 A CN104857196 A CN 104857196A
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radix
chinese medicine
medicine preparation
epidural anesthesia
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杨明德
于燕
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating epidural anesthesia nerve injuries. The traditional Chinese medicine preparation is prepared from the following raw materials: morinda officinalis, rhizoma curculiginis, eclipta, glossy privet fruit, cissus hexangularis, achyranthes aspera, humata repens rhizome, oplopanax elatus nakai, radix clematidis and earthworm. According to the traditional Chinese medicine preparation for treating epidural anesthesia nerve injuries, the defect of shortage of a special traditional Chinese medicine preparation for treating epidural anesthesia nerve injuries in the prior art is overcome; the curative effect on the epidural anesthesia nerve injuries is satisfying; the pain of a patient is relieved; and the incidence rate of patient-hospital disputes is lowered. 30 cases of patients are treated by a traditional Chinese medicine preparation decoction for treating the epidural anesthesia nerve injuries disclosed by the invention; the pain relief situation of a treatment group after treatment for two weeks is obviously superior to that of a control group; and the difference has statistical significance (P is smaller than 0.01).

Description

A kind of Chinese medicine preparation for the treatment of epidural anesthesia nerve injury
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, particularly a kind of Chinese medicine preparation for the treatment of epidural anesthesia nerve injury.
Background technology
Epidural anesthesia is the main anesthesia method that midriff is performed the operation with lower portion, and nerve injury is the major complications of epidural anesthesia.The root pain of postoperative appearance not only increases the misery of patient, extends the hospital stays, too increases the expense of patient simultaneously, sometimes even produce conflict between doctors and patients.The main processing mode of epidural anesthesia nerve injury applies adrenocortical hormone in art, lacks successive treatment measure.The present inventor, by clinical practice for many years, develops a kind of Chinese medicine preparation for the treatment of epidural anesthesia nerve injury, satisfactory effect.
Summary of the invention
The deficiency that the object of the invention is to overcome prior art puts forward, and namely provides one to treat epidural anesthesia nerve injury Chinese medicine preparation.
In order to realize foregoing invention object, the invention provides following technical scheme:
Treat a Chinese medicine preparation for epidural anesthesia nerve injury, be made up of the crude drug of following mass ratio: Radix Morindae Officinalis 9 ~ 15 parts, Rhizoma Curculiginis 9 ~ 15 parts, Herba Ecliptae 8 ~ 12 parts, Fructus Ligustri Lucidi 8 ~ 12 parts, Radix Cissi hexangularis 20 ~ 30 parts, Radix Achyranthis 10 ~ 20 parts, red hair Serpentis 30 ~ 50 parts, Radix Oplopanacis Elati 6 ~ 12 parts, Radix Clematidis 3 ~ 9 parts, Pheretima 3 ~ 9 parts.
The pharmacological action of raw material of Chinese medicine medicine of the present invention is as follows:
Radix Morindae Officinalis: pungent, sweet, tepor, returns kidney, Liver Channel.Reinforcing the kidney and supporting YANG, expelling wind and removing dampness.Cure mainly that insufficiency of kidney-YANG sexual impotence, cold womb are infertile, frequent micturition, rheumatism lumbocrural pain and soreness of the waist and knees of suffering from a deficiency of the kidney unable.
Rhizoma Curculiginis: pungent, hot, poisonous, returns kidney, Liver Channel.Warming the kidney to invigorate YANG, dispelling cold and dehumidification.Cure mainly insufficiency of kidney-YANG, the sexual impotence cold sperm of decline of the fire from the gate of life, frequent micturition; Chills and pain of the waist and kness, muscles and bones flaccidity is soft unable.
Herba Ecliptae: sweet, sour, cold, returns liver, kidney channel.Nourishing the liver and kidney, cooling blood for hemostasis.Cure mainly syndrome of yin deficiency of liver and kidney, the card of losing blood of YinXuXueRe.
Fructus Ligustri Lucidi: sweet, bitter, cool, returns liver, kidney channel.Nourishing the liver and kidney, crow must improving eyesight.Cure mainly syndrome of yin deficiency of liver and kidney.
Radix Cissi hexangularis: micro-hardship, cool.Dispelling, collateral-activating, removing blood stasis and activating blood flow.Cure mainly rheumatic arthritis, lumbar muscle strain, traumatic injury.
Radix Achyranthis: sweet, micro-hardship, micro-acid, cold, returns liver, spleen channel.Blood circulation promoting and blood stasis dispelling, eliminating fire and detoxication, inducing diuresis for treating stranguria syndrome.Cure mainly amenorrhea, traumatic injury, rheumatic arthritis, dysentery, diphtheria, laryngopharynx swelling and pain, carbuncle sore, stranguria, edema.
Red hair Serpentis: sweet, light, flat.Promoting blood circulation to remove blood stasis, clearing away heat-damp and promoting diuresis.Cure mainly rheumatic arthralgia, lumbar muscle strain, leucorrhea, spit blood, have blood in stool, urinary tract infection, traumatic injury, sore swollen toxin.
Radix Oplopanacis Elati: sweet, flat.Invigorating the spleen and replenishing QI, nourishing YIN and moistening the lung, reducing swelling and alleviating pain.Cure mainly insufficiency of the spleen lack of appetite weak, have loose bowels, proctoptosis, pulmonary tuberculosis hemoptysis, hectic fever, night sweat, spontaneous perspiration, the enuresis, hypogalactia in puerperal, carbuncle furuncle.
Radix Clematidis: pungent, salty, warm, returns urinary bladder channel.Eradicates rheumatism, removing obstruction in the collateral to relieve pain, the bone that disappears is choked.Cure mainly rheumatism arthromyodynia, bone is choked with sobs larynx.
Pheretima: salty, cold, returns liver, spleen, urinary bladder channel.Heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.Cure mainly high hot infantile convulsion, demented; Blood stagnancy due to deficiency of QI, hemiplegia; Arthromyodynia; Dysuria, urine retention is obstructed.
Epidural anesthesia nerve injury belongs to the categories such as the traditional Chinese medical science " arthromyodynia ".The traditional Chinese medical science thinks governor vessel governor whole body YANG pulse, is the sea of yang channels.Epidural anesthesia damage governor vessel, yang-energy is injured, unablely agitates QI-blood circulation, therefore produces series of symptoms.Control suitable warming the kidney to invigorate YANG, activating qi and collateral.The present invention adopts Radix Morindae Officinalis, Rhizoma Curculiginis warming the kidney to invigorate YANG; Herba Ecliptae, Fructus Ligustri Lucidi nourishing the liver and kidney, with treating YANG within YIN; Radix Cissi hexangularis, Radix Achyranthis, red hair Serpentis blood circulation promoting and blood stasis dispelling; Radix Oplopanacis Elati invigorating the spleen and replenishing QI, makes the capable then blood of gas; Radix Clematidis Eradicates rheumatism, removing obstruction in the collateral to relieve pain, its current 12 warps, descending with priming; Pheretima is calmed the frightened, dredging collateral.All medicines share, and hit pathogenesis.
Preferably, the Chinese medicine preparation of described treatment epidural anesthesia nerve injury is made up of the crude drug of following mass ratio: Radix Morindae Officinalis 11 ~ 13 parts, Rhizoma Curculiginis 11 ~ 13 parts, Herba Ecliptae 9 ~ 11 parts, Fructus Ligustri Lucidi 9 ~ 11 parts, Radix Cissi hexangularis 23 ~ 27 parts, Radix Achyranthis 13 ~ 17 parts, red hair Serpentis 35 ~ 45 parts, Radix Oplopanacis Elati 8 ~ 10 parts, Radix Clematidis 5 ~ 7 parts, Pheretima 5 ~ 7 parts.
Preferred further, the Chinese medicine preparation of described treatment epidural anesthesia nerve injury is made up of the crude drug of following mass ratio: Radix Morindae Officinalis 12 parts, Rhizoma Curculiginis 12 parts, Herba Ecliptae 10 parts, Fructus Ligustri Lucidi 10 parts, Radix Cissi hexangularis 25 parts, Radix Achyranthis 15 parts, red hair Serpentis 40 parts, Radix Oplopanacis Elati 9 parts, Radix Clematidis 6 parts, Pheretima 6 parts.
The Chinese medicine preparation of described treatment epidural anesthesia nerve injury can adopt existing Chinese medicine preparation technology to be prepared into any conventional oral preparations, such as can decocting be adopted to obtain water decoction said components, by other existing Chinese medicine preparation technology, the Chinese medicine preparation of described treatment epidural anesthesia nerve injury can also be prepared into tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
compared with prior art, beneficial effect of the present invention
The Chinese medicine preparation for the treatment of epidural anesthesia provided by the invention nerve injury, overcome the deficiency without treatment epidural anesthesia nerve injury Chinese medicine special preparation in prior art, treatment epidural anesthesia nerve injury satisfactory effect, alleviates patient suffering, and reduces doctor-patient dispute incidence rate.
treat a Chinese medicine preparation for epidural anesthesia nerve injury, clinical efficacy is summed up
1 physical data
60 routine patients are divided into matched group and treatment group at random, often organize 30 examples.Include man 11 example in matched group, female 19 example, 7 ~ 80 years old age, average (47.8 ± 13.0) year; Include man 10 example in treatment group, female 20 example, 8 ~ 81 years old age, average (48.0 ± 12.5) year.Two groups of patient's physical data no significant difference (P > 0.05), have comparability.
2 diagnostic criterias
Reference literature standard (accounts for big building, FT-207. the clinical observation of peripheral nerve injury after Neurotropin In Treatment intravertebral anesthesia. Chinese pain medicine magazine, 2009,14:329-331.): patients during epidural anesthesia exists the corresponding abnormal sensory such as skin lamellar numbness, pain of the Substance P relevant with puncture, twitch in certain position of side limb adynamia, lower limb, homonymy vola pain person is all considered as nerve injury occurs.
3 Therapeutic Method
Two groups of patients all apply the treatment such as adrenocortical hormone, Neurotrophic drugs, and treatment group is oral Chinese medicine preparation water decoction provided by the invention simultaneously, composed as follows:
Radix Morindae Officinalis 12 grams, Rhizoma Curculiginis 12 grams, Herba Ecliptae 10 grams, Fructus Ligustri Lucidi 10 grams, Radix Cissi hexangularis 25 grams, Radix Achyranthis 15 grams, red hair Serpentis 40 grams, Radix Oplopanacis Elati 9 grams, Radix Clematidis 6 grams, Pheretima 6 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
4 therapeutic outcomes
4.1 observation index: adopt Visual Analogue Scale measurement (visual analogue scale, VAS) to assess the pain degree of patient, 0 point indicates without pain, 10 points represent insufferable severe pain.
4.2 results: as in the attached table, treatment group pain relief situation is obviously better than matched group to two groups of patient treatments, 2 weeks rear pain relief situations, and difference has statistical significance (P<0.01).
Subordinate list two groups of patient pain are alleviated situation and are compared
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.
Embodiment 1
A kind of Chinese medicine preparation for the treatment of epidural anesthesia nerve injury, by Radix Morindae Officinalis 15 grams, Rhizoma Curculiginis 15 grams, Herba Ecliptae 12 grams, Fructus Ligustri Lucidi 12 grams, Radix Cissi hexangularis 30 grams, Radix Achyranthis 20 grams, red hair Serpentis 50 grams, Radix Oplopanacis Elati 12 grams, Radix Clematidis 9 grams, Pheretima 9 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 2
A kind of Chinese medicine preparation for the treatment of epidural anesthesia nerve injury, by Radix Morindae Officinalis 13 grams, Rhizoma Curculiginis 13 grams, Herba Ecliptae 11 grams, Fructus Ligustri Lucidi 11 grams, Radix Cissi hexangularis 27 grams, Radix Achyranthis 17 grams, red hair Serpentis 45 grams, Radix Oplopanacis Elati 10 grams, Radix Clematidis 7 grams, Pheretima 7 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 3
A kind of Chinese medicine preparation for the treatment of epidural anesthesia nerve injury, by Radix Morindae Officinalis 12 grams, Rhizoma Curculiginis 12 grams, Herba Ecliptae 10 grams, Fructus Ligustri Lucidi 10 grams, Radix Cissi hexangularis 25 grams, Radix Achyranthis 15 grams, red hair Serpentis 40 grams, Radix Oplopanacis Elati 9 grams, Radix Clematidis 6 grams, Pheretima 6 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 4
A kind of Chinese medicine preparation for the treatment of epidural anesthesia nerve injury, by Radix Morindae Officinalis 11 grams, Rhizoma Curculiginis 11 grams, Herba Ecliptae 9 grams, Fructus Ligustri Lucidi 9 grams, Radix Cissi hexangularis 23 grams, Radix Achyranthis 13 grams, red hair Serpentis 35 grams, Radix Oplopanacis Elati 8 grams, Radix Clematidis 5 grams, Pheretima 5 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 5
A kind of Chinese medicine preparation for the treatment of epidural anesthesia nerve injury, by Radix Morindae Officinalis 9 grams, Rhizoma Curculiginis 9 grams, Herba Ecliptae 8 grams, Fructus Ligustri Lucidi 8 grams, Radix Cissi hexangularis 20 grams, Radix Achyranthis 10 grams, red hair Serpentis 30 grams, Radix Oplopanacis Elati 6 grams, Radix Clematidis 3 grams, Pheretima 3 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.

Claims (4)

1. treat a Chinese medicine preparation for epidural anesthesia nerve injury, it is characterized in that being made up of the crude drug of following mass ratio:
Radix Morindae Officinalis 9 ~ 15 parts, Rhizoma Curculiginis 9 ~ 15 parts, Herba Ecliptae 8 ~ 12 parts, Fructus Ligustri Lucidi 8 ~ 12 parts, Radix Cissi hexangularis 20 ~ 30 parts, Radix Achyranthis 10 ~ 20 parts, red hair Serpentis 30 ~ 50 parts, Radix Oplopanacis Elati 6 ~ 12 parts, Radix Clematidis 3 ~ 9 parts, Pheretima 3 ~ 9 parts.
2. the Chinese medicine preparation for the treatment of epidural anesthesia as claimed in claim 1 nerve injury, is characterized in that being made up of the crude drug of following mass ratio:
Radix Morindae Officinalis 11 ~ 13 parts, Rhizoma Curculiginis 11 ~ 13 parts, Herba Ecliptae 9 ~ 11 parts, Fructus Ligustri Lucidi 9 ~ 11 parts, Radix Cissi hexangularis 23 ~ 27 parts, Radix Achyranthis 13 ~ 17 parts, red hair Serpentis 35 ~ 45 parts, Radix Oplopanacis Elati 8 ~ 10 parts, Radix Clematidis 5 ~ 7 parts, Pheretima 5 ~ 7 parts.
3. the Chinese medicine preparation for the treatment of epidural anesthesia as claimed in claim 1 nerve injury, is characterized in that being made up of the crude drug of following mass ratio:
Radix Morindae Officinalis 12 parts, Rhizoma Curculiginis 12 parts, Herba Ecliptae 10 parts, Fructus Ligustri Lucidi 10 parts, Radix Cissi hexangularis 25 parts, Radix Achyranthis 15 parts, red hair Serpentis 40 parts, Radix Oplopanacis Elati 9 parts, Radix Clematidis 6 parts, Pheretima 6 parts.
4. treat the preparation method of the Chinese medicine preparation of epidural anesthesia nerve injury as claimed in claim 1, it is characterized in that the Chinese medicinal components of described mass ratio to be prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
CN201510315398.2A 2015-06-11 2015-06-11 Traditional Chinese medicine preparation for treating epidural anesthesia nerve injuries Pending CN104857196A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102973708A (en) * 2011-09-06 2013-03-20 江中药业股份有限公司 Anti-aging traditional Chinese medicine composition and preparation method thereof
CN104740213A (en) * 2015-04-23 2015-07-01 张思彦 Traditional Chinese medicine for treating epidural anesthesia nerve injury

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102973708A (en) * 2011-09-06 2013-03-20 江中药业股份有限公司 Anti-aging traditional Chinese medicine composition and preparation method thereof
CN104740213A (en) * 2015-04-23 2015-07-01 张思彦 Traditional Chinese medicine for treating epidural anesthesia nerve injury

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Application publication date: 20150826