CN104857073A - Sinkiang-arnebia-root-containing skin-care traditional Chinese medicine composition, sinkiang-arnebia-root-containing skin-care cream and preparation method of sinkiang-arnebia-root-containing skin-care traditional Chinese medicine composition and sinkiang-arnebia-root-containing skin-care cream - Google Patents
Sinkiang-arnebia-root-containing skin-care traditional Chinese medicine composition, sinkiang-arnebia-root-containing skin-care cream and preparation method of sinkiang-arnebia-root-containing skin-care traditional Chinese medicine composition and sinkiang-arnebia-root-containing skin-care cream Download PDFInfo
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Abstract
The invention relates to sinkiang-arnebia-root-containing skin-care traditional Chinese medicine composition and a preparation method thereof. Effective components of the sinkiang-arnebia-root-containing skin-care traditional Chinese medicine composition are prepared from raw materials in parts by weight as follows: 30-70 parts of sinkiang arnebia roots, 15-45 parts of boswellia serrate, 5-15 parts of liquorice and 1-10 parts of rosemary leaves. The preparation method is characterized in that a method of stir-frying traditional Chinese medicines with honey is adopted, dissolution of effective substances is promoted, the effective preservation life of extracts is prolonged, besides, meadowfoam seed oil is taken as a solvent and performs a synergistic anti-oxidation function along with the rosemary leaves added to the meadowfoam seed oil. The invention further provides sinkiang-arnebia-root-containing skin-care cream. The sinkiang-arnebia-root-containing skin-care cream is mainly prepared from raw materials as follows: the traditional Chinese medicine composition, maize germ oil, beewax, cocoa seed butter, natural tocopherol, avocado oil, lavender essential oil, mango seed butter, lanolin and prinsepia utilis royle oil. The sinkiang-arnebia-root-containing skin-care cream is environment-friendly and safe and can effectively promote self-healing of the skin of infants and improve the skin barrier function.
Description
Technical field
The present invention relates to cosmetics and medical art, be specifically related to a kind of infant Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions and Radix Arnebiae (Radix Lithospermi) cold cream and preparation method thereof.
Background technology
Skin is the maximum organ of human body, mainly carries protection health, perspire, feels cold and hot and the function such as pressure.Skin covers whole body, and it to make in body various tissue and organ from the invasion and attack of physical property, mechanicalness, chemical and pathogenic microorganism.For infant, skin is not yet reached maturity, and lacks the lipid keeping skin integrity, and barrier function is fragile, and self-repairing capability is weak, easily allows the material bringing out inflammation infiltrate skin inside, makes skin immune system abnormal response, thus pathological changes occurs.Such as infant easily sends out eczema, red and swollen by easy pruritus after mosquito bite and the main cause of the common skin problem such as not disappear lastingly is exactly rise therefrom.Therefore, can effectively promote skin self-regeneration, the skin-care products for infant promoting skin barrier function has the very large market demand.
Although but the current product kind on the market for infant problem skin is many, quality is very different, effect is difficult to ensure, and has certain side effect.As: patent CN201410216490.9 discloses a kind of multiple-effect Oleum Camelliae zicao soft plaster.This multiple-effect Oleum Camelliae zicao soft plaster is made up of the raw material of following weight portion: Radix Arnebiae (Radix Lithospermi) 15-25 part, mentha leave 2-4 part, Radix Notoginseng 8-12 part, Olibanum quintessence oil 3-5 part, orange oil 4-5 part, Semen Tritici aestivi germ oil 4-5 part, Oleum Camelliae 20-30 part, shea butter 10-20 part, vaseline 40-50 part, Cera Flava 10-20 part, allantoin 10-15 part, milk 60-80 part, Mel 40-50 part and deionized water 200-250 part.The step of its preparation method is as follows: Olibanum quintessence oil, orange oil, Semen Tritici aestivi germ oil mix homogeneously are made mixed essential oil by proportioning by (1); (2) pulverize Radix Arnebiae (Radix Lithospermi) for coarse powder, add alcohol reflux 1-3h, filter, filtrate is recycled to without alcohol taste, obtains alcohol-extracted extract; (3) mentha leave, Radix Notoginseng decoct with water twice, first time 1-2 hour, and second time 0.5-1.5 hour, merges twice Aqueous extracts, filters, and are the clear paste of 1.20-1.24 to density when filtrate is concentrated into 80 DEG C; (4) by allantoin, milk, Mel and deionized water and stirring mix homogeneously; (5) Oleum Camelliae, shea butter, vaseline are fused into ointment base with Cera Flava mixing post-heating, temperature is 70-80 DEG C; (6) mixed by the product of step (1) to (4), dispersed with stirring is even, adds in ointment base, stirs, be cooled to after after room temperature and get product.But there is following problem in above-mentioned multiple-effect Oleum Camelliae zicao soft plaster: one, from formulation composition, this multiple-effect Oleum Camelliae zicao soft plaster is oil water two phase system, it is a kind of cold cream, but only use the very weak Cera Flava of emulsifying capacity to make emulsifying agent, and do not add antiseptic, obtained product stability is poor, and shelf life is not long; Two, for impaired skin, wound can be stimulated after smearing moisture skin care item to bring pain, be unfavorable for the self-regeneration of skin.Patent CN93111471.3 discloses a kind of WEIFU GAO, this WEIFU GAO adds fluocinonide, fluocinonide is a kind of potent glucocorticoid external preparation, long-term or large-area applications, atrophoderma, telangiectasis, folliculitis, increase can be caused problems such as the susceptibilitys infected, be applied to face and acne sample dermatitis, Perioral Dermatitis etc. can occur, occasionally can cause contact dermatitis.Also add permeation enhancers dimethyl sulfoxide in this WEIFU GAO in addition, dimethyl sulfoxide stimulates eyes, respiratory system and skin, is that " cosmetics health specification " forbids raw material.
Summary of the invention
Based on this, be necessary for product in prior art unstable, side effect is obvious, and the problem of poor effect, provides one Radix Arnebiae (Radix Lithospermi) skin-protection product safely and effectively, effectively can promote the self-regeneration of infant skin, promotes skin barrier function.
The concrete technical scheme solved the problems of the technologies described above is as follows:
A kind of Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 30-70 part, boswellia serrata 15-45 part, Radix Glycyrrhizae 5-15 part, leaf of Herba Rosmarini Officinalis 1-10 part.
Wherein in an embodiment, the effective ingredient of described Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 60 parts, boswellia serrata 25 parts, 10 parts, Radix Glycyrrhizae, leaf of Herba Rosmarini Officinalis 5 parts.
Present invention also offers a kind of Radix Arnebiae (Radix Lithospermi) cold cream, the raw material primarily of following percetage by weight is prepared from:
Wherein in some embodiments, described Radix Arnebiae (Radix Lithospermi) cold cream is prepared from primarily of the raw material of following percetage by weight:
Raw material of the present invention is described below:
Radix Arnebiae extract, extracts obtained from Radix Arnebiae (Radix Lithospermi).Radix Arnebiae (Radix Lithospermi) is Boraginaceae herbaceos perennial, sweet in the mouth, salty, cold, GUIXIN, Liver Channel; Function clearing away heat and cooling blood, invigorates blood circulation, malicious rash, all on the books in Shennong's Herbal and Compendium of Material Medica.Clinical practice is contained in epidemic febrile disease heat in blood poison, and macule purple is black, measles without adequate eruption; Skin infection, eczema, burn due to hot liquid or fire.
Boswellia serrata extract, extracts obtained from boswellia serrata.Boswellia serrata is the one of Olibanum, and traditionally, it is used to arthritis, antiinflammatory, and antidiarrheal prevents dysentery, diuresis, and diaphoresis is brought down a fever, and treatment peptic ulcer, stimulates the menstrual flow.Modern study shows that the boswellic acid contained in Olibanum can suppress the synthesis of leukotriene, has antiinflammatory action.
Radix Glycyrrhizae extract, extracts obtained from licorice.Radix Glycyrrhizae property is flat, taste is sweet, and be the Chinese medicine of QI invigorating strengthening the spleen simply, QI invigorating, strengthening the spleen, also have the function of heat-clearing and toxic substances removing, diuresis promoting.Radix Glycyrrhizae energy emergency, can also play the mediation effect to all medicines.
Rosemary leaf extract, extract to obtain from plant rosemary leaf, it is a kind of generally acknowledged Natural antioxidant, principle active component is diterpene phenols, flavonoid and a small amount of triterpenoid compound, safety non-toxic, resistance to 190 DEG C of high temperature, antioxidant effect is higher than Butylated hydroxyanisole (BHA) and 2, the synthesis such as 6-di-tert-butyl-4-methy phenol (BHT) antioxidant, mainly as oil antioxidant, for in fried food, rich oil food and each quasi-grease, prevent Oxidation of Fat and Oils from going bad.
Fructus Maydis oil, one of 16 kinds of edible oil and fat of FAO (Food and Agriculture Organization of the United Nation) and World Health Organization's food standard safety accreditation, fatty acid composition more than 80% is unsaturated fatty acid, wherein linoleic acid content reach 60%, linolenic acid content 1%, oleic acid content about 30%, also containing nutritional labelings such as vitamin E, vitamin A, lecithin, plant sterol, beta-carotene, gamma oryzanols, be described as " liquid golden ".
Cera Flava, the solid state wax of Chinese Mel secretion, is loaded in Shennong's Herbal as drug use head, records it and cure mainly dysentery pus and blood, invigorating middle warmer, Radix Dipsaci wound gold wound, and QI invigorating is not hungry, always resistance to.Compendium of Material Medica records that it cures mainly dysentery pus and blood, burn and scald injures various sore.2005 version " Chinese Pharmacopoeia " include its astringent therapy, sore, granulation promoting, pain relieving; Outer for ulcer being unable to heal, ecthyma is rotten to the corn, wound, burn.
Cocoa seed fat, a kind of vegetable stearin extracted from cocoa seed, forms primarily of 98% sweet three esters, 1% free fatty, 0.3% DAG, 0.2% monoglyceride, 150mg/kg ~ 250mg/kg tocopherol and 0.05% ~ 0.13% phospholipid.Cocoa seed fat is hard and frangible below 27 DEG C, starts fusing when temperature crosses very narrow interval (27 DEG C ~ 33 DEG C), when temperature reaches 35 DEG C, and basic fine melt.
Natural tocopherol, also known as natural Vitamin E, extracts usually from vegetable oil, soybean oil, Semen Tritici aestivi germ oil, golden yellow or faint yellow sticky oil thing, mainly comprises four kinds only containing tocopherol and the corresponding tocotrienol composition thereof of dextrorotation optical isomer.There is remarkable antioxygenic property, the generation of human free radical can be suppressed, delay skin aging.
Butyrospermum parkii fruit fatty oil, also known as shea butter, solid grease, its feature is that the indices secreting oils and fats with human sebaceous is the most close, contains abundant non-saponified composition, very easily in absorption of human body, can not only season cracking be prevented, can also recover further and keep the natural elasticity of skin.Modern study shows that it has similar structure to the fatty acid in skin, the unsaturated double-bond existed in molecule makes it have asymmetric space structure, when fatty acid molecule inserts the lipid bilayer hydrophobic structure of horny layer lipoid, due to the cis-structure of its unsaturated hydrophobic chain, bilayer is reversed, form the fine mobility passage being easy to permeate, effectively affect the ordered arrangement of Stratum corneum lipids structure, thus promote the percutaneous absorbtion of medicine.
Herba Lysimachiae foenum-graeci quintessence oil, extract again through arranging obtained quintessence oil from the inflorescence that lavandula angustifolia is opening, its main component is linalool (37.60%), linalyl acetate (35.79%), 4-terpineol (4.51%), acetic acid lavandula angustifolia esters (4.11%) etc., type of compounds is based on acetas, alcohol, olefin(e) compound.Research shows, Herba Lysimachiae foenum-graeci quintessence oil has the pharmacological actions such as convulsion, calmness, function of gallbladder promoting, wind dispelling, anthelmintic.
Fructus Mangifera Indicae seed fat, solid grease, derives from Fructus Mangifera Indicae kernel, by saturated fatty acid glyceride, monoolein, diolein and glycerol three unsaturated acid ester form, also containing a small amount of sitosterol.Fructus Mangifera Indicae seed fat is a kind of skin protection oils and fats of pure natural, good with the human body skin compatibility, can keep the moisture of skin, skin nutrition.
Lanoline, it is the one secretion oils and fats be attached on Pilus Caprae seu Ovis, for soft paste that is faint yellow or brown color, the ester that main component is sterols, the fatty acid of aliphatic alcohols and triterpene alcohols and about equivalent generates, account for 95%, also containing free alcohol 4%, and there are a small amount of free fatty and hydrocarbons.For principal agent can be made in ointment to be absorbed by mucosa and skin rapidly, there is adhesive force, stable in properties, and can absorb water, not easily become sour.
Princepia utilis oil, all on the books in the ancient books and records such as " the southern regions of the Yunnan Province book on Chinese herbal medicine ", " cosmopolitian plant stack room ".Princepia utilis has heat clearing away, detoxify, invigorate blood circulation, the effect such as help digestion, and kernel is rich in abundant Princepia utilis oil.Princepia utilis oil is a kind of skin protection oils and fats of pure natural, with human body lipid closely, easily absorbed by human body skin, the moisture of skin, nutrition and elasticity can be kept, make the dry and comfortable lubrication of skin.
Present invention also offers the preparation method of described Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions, comprise the following steps:
1) pick: remove in Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis go mouldy, damage by worms, sick scar part, removal of inclusions;
2) pulverize: by Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis mixing, pulverize, screening, obtained mixed-powder;
3) processed with honey: mixed-powder is immersed in Mel, then dry obtained processed with honey powder;
4) lixiviate: be immersed in white Limnanthes Alba Seed Oil by processed with honey powder, constantly stir, obtains lixiviate mixture;
5) ultrasonic extraction: heated by lixiviate mixture, by ultrasonic Treatment, stirs, obtains extraction mixture;
6) filter: mixture will be extracted and filter, and be cooled to room temperature, and obtain Chinese medicine composition.
Wherein in some embodiments, the preparation method of described Chinese medicine composition comprises the following steps:
1) pick: remove in Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis go mouldy, damage by worms, sick scar part, removal of inclusions;
2) pulverize: Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis mixing, coarse crushing is less than 20mm to granularity, then is crushed to pulverulence further, carry out sieving and the powder retaining below 20 orders for following process, obtained mixed-powder;
3) processed with honey: mixed-powder is immersed in 3-5 hour (Mel of the mixed-powder 2kg of 1kg) in Mel, then dries obtained processed with honey powder;
4) lixiviate: be immersed in by processed with honey powder (the white Limnanthes Alba Seed Oil of the processed with honey powder 10-20kg of 1kg) in white Limnanthes Alba Seed Oil, constantly stir in immersion process, soaks 8-12 hour, obtains lixiviate mixture;
5) ultrasonic extraction: lixiviate mixture is heated to 55-65 DEG C, open frequency is the ultrasonic Treatment 5-10 minute of 20kHz, then stirs 1-2 hour, obtains extraction mixture;
6) filter: extraction mixture filtering accuracy 200 object filter material is filtered, is cooled to room temperature, obtain Chinese medicine composition.
Described step 3) adopt the way of Chinese medicine processed with honey, with soaking in Mel Radix Arnebiae (Radix Lithospermi), boswellia serrata and Radix Glycyrrhizae, enhance the dissolving of working substance in Radix Arnebiae (Radix Lithospermi), boswellia serrata and Radix Glycyrrhizae, thus improve the extraction quantity of working substance; Mel can also play antiseptical effect, promotes the shelf life of extract.
Described step 4) preferred white Limnanthes Alba Seed Oil is as solvent; white Limnanthes Alba Seed Oil contains the long-chain fatty acid with antioxidation of more than 95%; collaborative antioxidation can be played with the leaf of Herba Rosmarini Officinalis added wherein; farthest protect the activity of effective ingredient in Radix Arnebiae (Radix Lithospermi), boswellia serrata and Radix Glycyrrhizae, avoid oxidation.
The preparation method of the Chinese medicine composition in described Radix Arnebiae (Radix Lithospermi) cold cream, whole extraction process has the feature of extraction conditions gentleness, environmental protection, and product itself, not by pollutions such as solvents, also can not produce pollution by environment to external world.
Present invention also offers the preparation method of described Radix Arnebiae (Radix Lithospermi) cold cream, described Radix Arnebiae (Radix Lithospermi) cold cream can by the preparation of conventional production technology, and wherein in some embodiments, its preparation method comprises the following steps:
1) Chinese medicine composition is prepared by the method for the invention;
2) described Fructus Maydis oil, Cera Flava, cocoa seed fat, Butyrospermum parkii fruit fatty oil, Fructus Mangifera Indicae seed fat, lanoline are added agitated kettle, heating, stirring and dissolving, obtains lysate;
3) by lysate lower the temperature, add tocopherol, step 1) described Chinese medicine composition, Herba Lysimachiae foenum-graeci quintessence oil, Princepia utilis oil, stir, cooling, obtain described Radix Arnebiae (Radix Lithospermi) cold cream.
Wherein in some embodiments, the preparation method of described Radix Arnebiae (Radix Lithospermi) cold cream comprises the following steps:
1) Chinese medicine composition is prepared by the method for the invention;
2) above-mentioned Fructus Maydis oil, Cera Flava, cocoa seed fat, Butyrospermum parkii fruit fatty oil, Fructus Mangifera Indicae seed fat, lanoline are added in agitated kettle be warming up to 70-80 DEG C, stirring and dissolving, obtain lysate;
3) lysate is cooled to 50 DEG C, adds tocopherol, Chinese medicine composition, Herba Lysimachiae foenum-graeci quintessence oil, Princepia utilis oil, stir, be cooled to 20-30 DEG C, obtain finished product.
The present invention is raw materials used all by commercially available acquisition, and as preferably, described Fructus Maydis oil, Princepia utilis oil are prepared from by milling process.
Compared with prior art, the present invention has following beneficial effect:
1, the Chinese medicine composition that four kinds of Chinese crude drugs are prepared from is contained in Radix Arnebiae (Radix Lithospermi) cold cream provided by the invention, in Radix Arnebiae (Radix Lithospermi) cold cream, four kinds of Chinese crude drugs are arranged in pairs or groups according to special ratios, the multiple efficacies composition be rich in is in harmonious proportion mutually, collaborative, make Radix Arnebiae (Radix Lithospermi) cold cream effectively can promote the self-regeneration of infant skin, promote infant skin barrier function, prevention or therapeutical effect are played to the pruritus of infant common skin problem as eczema and mosquito bite and insect bite cause.
2, all raw materials that Radix Arnebiae (Radix Lithospermi) cold cream provided by the invention adopts all are originated natural, environmental protection, and formula is all oil system, and do not add antiseptic and antibiotic, gentleness does not stimulate, and meet the trend trend of skin-care products for infant development.The present invention, by liquid fat and the ingenious collocation of solid grease, makes the melting point of product close to body temperature, spreads upon on skin and can melt drawout rapidly, have good use sense.
3, the preferred Radix Arnebiae (Radix Lithospermi) cold cream of the present invention contains Radix Arnebiae extract, boswellia serrata extract, Radix Glycyrrhizae extract, Cera Flava, natural tocopherol, Princepia utilis oil, Semen Maydis oil, Fructus Mangifera Indicae seed fat, arrange in pairs or groups according to special ratios, the multiple efficacies composition be rich in is in harmonious proportion mutually, collaborative, make Radix Arnebiae (Radix Lithospermi) cold cream promote infant skin barrier function further and promote the effect of infant skin self-repairing capability.The lanoline contained in the preferred Radix Arnebiae (Radix Lithospermi) cold cream of the present invention, Butyrospermum parkii fruit fatty oil and Herba Lysimachiae foenum-graeci quintessence oil, there is good short penetrating power, the effective ingredient in product can be made to reach deep skin tissue through epidermis quickly, also can be the nutrient that skin provides sufficient, enhance metabolism, make product effect better.
Through repetition test, component proportion of the present invention can reach maximum product efficacy.Experiment proves: Radix Arnebiae (Radix Lithospermi) cold cream provided by the present invention can stimulate the expression of basic fibroblast growth factor (bFGF), cell division and propagation are accelerated, thus acceleration wound healing, continuous use has obvious therapeutic effect to eczema in 7 days, and in the use procedure of product prepared by the present invention, do not find toxic and side effects and zest.
Detailed description of the invention
Below with reference to specific embodiment, the invention will be further described, for the technological parameter do not indicated especially or condition, can refer to routine techniques and carry out.
Embodiment 1
Experiment 1, a kind of Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions, its effective ingredient is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 70 parts, boswellia serrata 15 parts, 5 parts, Radix Glycyrrhizae, leaf of Herba Rosmarini Officinalis 10 parts.
The preparation method of this Chinese medicine composition comprises the following steps:
1) take each medical material component: Radix Arnebiae (Radix Lithospermi) 70g, boswellia serrata 15g, Radix Glycyrrhizae 5g, leaf of Herba Rosmarini Officinalis 10g, medical material amounts to 100g;
2) pick: remove in Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis go mouldy, damage by worms, sick scar part, removal of inclusions;
3) pulverize: Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis mixing, coarse crushing is less than 20mm to granularity, then is crushed to pulverulence further, carry out sieving and the powder retaining below 20 orders for following process, obtained mixed-powder;
4) processed with honey: mixed-powder to be immersed in 200g Mel 3 hours, then to dry obtained processed with honey powder;
5) lixiviate: be immersed in by processed with honey powder in the white Limnanthes Alba Seed Oil of 1500g, constantly stir in immersion process, soaks 12 hours, obtains lixiviate mixture;
6) ultrasonic extraction: lixiviate mixture is heated to 55 DEG C, open frequency is the ultrasonic Treatment 8 minutes of 20kHz, then stirs 1.5 hours, obtains extraction mixture;
7) filter: extraction mixture filtering accuracy 200 object filter material is filtered, is cooled to room temperature, obtains described Chinese medicine composition.
Experiment 2, a kind of Radix Arnebiae (Radix Lithospermi) cold cream, raw material primarily of following percetage by weight is prepared from: Chinese medicine composition 5% described in experiment 1, Fructus Maydis oil 45%, Cera Flava 5.9%, cocoa seed fat 20%, natural tocopherol 0.1%, Butyrospermum parkii fruit fatty oil 5%, Herba Lysimachiae foenum-graeci quintessence oil 3%, Fructus Mangifera Indicae seed fat 10%, lanoline 1%, Princepia utilis oil 5%.
The preparation method of this Radix Arnebiae (Radix Lithospermi) cold cream comprises the following steps:
1) percent takes following raw material by weight: Chinese medicine composition 5%, Fructus Maydis oil 45%, Cera Flava 5.9%, cocoa seed fat 20%, natural tocopherol 0.1%, Butyrospermum parkii fruit fatty oil 5%, Herba Lysimachiae foenum-graeci quintessence oil 3%, Fructus Mangifera Indicae seed fat 10%, lanoline 1%, Princepia utilis oil 5% described in experiment 1.
2) above-mentioned Fructus Maydis oil, Cera Flava, cocoa seed fat, Butyrospermum parkii fruit fatty oil, Fructus Mangifera Indicae seed fat, lanoline are added in agitated kettle be warming up to 75 DEG C, stirring and dissolving, obtain lysate;
3) lysate is cooled to 50 DEG C, adds above-mentioned tocopherol, Chinese medicine composition, Herba Lysimachiae foenum-graeci quintessence oil, Princepia utilis oil, stir, be cooled to 30 DEG C, obtain finished product.
Embodiment 2
Experiment 1, a kind of Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions, its effective ingredient is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 50 parts, boswellia serrata 35 parts, 14 parts, Radix Glycyrrhizae, leaf of Herba Rosmarini Officinalis 1 part.
The preparation method of this Chinese medicine composition comprises the following steps:
1) take each medical material component: Radix Arnebiae (Radix Lithospermi) 50g, boswellia serrata 35g, Radix Glycyrrhizae 14g, leaf of Herba Rosmarini Officinalis 1g, medical material amounts to 100g;
2) pick: remove in Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis go mouldy, damage by worms, sick scar part, removal of inclusions;
3) pulverize: Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis mixing, coarse crushing is less than 20mm to granularity, then is crushed to pulverulence further, carry out sieving and the powder retaining below 20 orders for following process, obtained mixed-powder;
4) processed with honey: mixed-powder to be immersed in 200g Mel 5 hours, then to dry obtained processed with honey powder;
5) lixiviate: be immersed in by processed with honey powder in the white Limnanthes Alba Seed Oil of 1000g, constantly stir in immersion process, soaks 8 hours, obtains lixiviate mixture;
6) ultrasonic extraction: lixiviate mixture is heated to 60 DEG C, open frequency is the ultrasonic Treatment 5 minutes of 20kHz, then stirs 1 hour, obtains extraction mixture;
7) filter: extraction mixture filtering accuracy 200 object filter material is filtered, is cooled to room temperature, obtains described Chinese medicine composition.
Experiment 2, a kind of Radix Arnebiae (Radix Lithospermi) cold cream, raw material primarily of following percetage by weight is prepared from: Chinese medicine composition 20% described in experiment 1, Fructus Maydis oil 6%, Cera Flava 20%, cocoa seed fat 6%, natural tocopherol 10%, Butyrospermum parkii fruit fatty oil 7%, Herba Lysimachiae foenum-graeci quintessence oil 10%, Fructus Mangifera Indicae seed fat 1%, lanoline 5%, Princepia utilis oil 15%.
The preparation method of this Radix Arnebiae (Radix Lithospermi) cold cream comprises the following steps:
1) percent takes following raw material by weight: Chinese medicine composition 20%, Fructus Maydis oil 6%, Cera Flava 20%, cocoa seed fat 6%, natural tocopherol 10%, Butyrospermum parkii fruit fatty oil 7%, Herba Lysimachiae foenum-graeci quintessence oil 10%, Fructus Mangifera Indicae seed fat 1%, lanoline 5%, Princepia utilis oil 15% described in experiment 1.
Step 2) and 3) with embodiment 1.
Embodiment 3
Experiment 1, a kind of Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions, its effective ingredient is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 30 parts, boswellia serrata 45 parts, 15 parts, Radix Glycyrrhizae, leaf of Herba Rosmarini Officinalis 10 parts.
The preparation method of this Chinese medicine composition comprises the following steps:
1) take each medical material component: Radix Arnebiae (Radix Lithospermi) 30g, boswellia serrata 45g, Radix Glycyrrhizae 15g, leaf of Herba Rosmarini Officinalis 10g, medical material amounts to 100g;
2) pick: remove in Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis go mouldy, damage by worms, sick scar part, removal of inclusions;
3) pulverize: Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis mixing, coarse crushing is less than 20mm to granularity, then is crushed to pulverulence further, carry out sieving and the powder retaining below 20 orders for following process, obtained mixed-powder;
4) processed with honey: mixed-powder to be immersed in 200g Mel 4 hours, then to dry obtained processed with honey powder;
5) lixiviate: be immersed in by processed with honey powder in the white Limnanthes Alba Seed Oil of 2000g, constantly stir in immersion process, soaks 12 hours, obtains lixiviate mixture;
6) ultrasonic extraction: lixiviate mixture is heated to 65 DEG C, open frequency is the ultrasonic Treatment 10 minutes of 20kHz, then stirs 2 hours, obtains extraction mixture;
7) filter: extraction mixture filtering accuracy 200 object filter material is filtered, is cooled to room temperature, obtains described Chinese medicine composition.
Experiment 2, a kind of Radix Arnebiae (Radix Lithospermi) cold cream, raw material primarily of following percetage by weight is prepared from: Chinese medicine composition 15% described in experiment 1, Fructus Maydis oil 5%, Cera Flava 5%, cocoa seed fat 5%, natural tocopherol 2.5%, Butyrospermum parkii fruit fatty oil 20%, Herba Lysimachiae foenum-graeci quintessence oil 1%, Fructus Mangifera Indicae seed fat 1%, lanoline 0.5%, Princepia utilis oil 45%.
The preparation method of this Radix Arnebiae (Radix Lithospermi) cold cream comprises the following steps:
1) percent takes following raw material by weight: Chinese medicine composition 15% described in experiment 1, Fructus Maydis oil 5%, Cera Flava 5%, cocoa seed fat 5%, natural tocopherol 2.5%, Butyrospermum parkii fruit fatty oil 20%, Herba Lysimachiae foenum-graeci quintessence oil 1%, Fructus Mangifera Indicae seed fat 1%, lanoline 0.5%, Princepia utilis oil 45%.
Step 2) and 3) with embodiment 1.
Embodiment 4
Experiment 1, a kind of Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions, its effective ingredient is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 60 parts, boswellia serrata 25 parts, 10 parts, Radix Glycyrrhizae, leaf of Herba Rosmarini Officinalis 5 parts.
The preparation method of this Chinese medicine composition comprises the following steps:
1) take each medical material component: Radix Arnebiae (Radix Lithospermi) 60g, boswellia serrata 25g, Radix Glycyrrhizae 10g, leaf of Herba Rosmarini Officinalis 5g, medical material amounts to 100g;
2) pick: remove in Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis go mouldy, damage by worms, sick scar part, removal of inclusions;
3) pulverize: Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis mixing, coarse crushing is less than 20mm to granularity, then is crushed to pulverulence further, carry out sieving and the powder retaining below 20 orders for following process, obtained mixed-powder;
4) processed with honey: mixed-powder to be immersed in 200g Mel 5 hours, then to dry obtained processed with honey powder;
5) lixiviate: be immersed in by processed with honey powder in the white Limnanthes Alba Seed Oil of 1200g, constantly stir in immersion process, soaks 9 hours, obtains lixiviate mixture;
6) ultrasonic extraction: lixiviate mixture is heated to 60 DEG C, open frequency is the ultrasonic Treatment 7 minutes of 20kHz, then stirs 1.5 hours, obtains extraction mixture;
7) filter: extraction mixture filtering accuracy 200 object filter material is filtered, is cooled to room temperature, obtains described Chinese medicine composition.
Experiment 2, a kind of Radix Arnebiae (Radix Lithospermi) cold cream, raw material primarily of following percetage by weight is prepared from: Chinese medicine composition 15% described in experiment 1, Fructus Maydis oil 20%, Cera Flava 12%, cocoa seed fat 11%, natural tocopherol 5%, Butyrospermum parkii fruit fatty oil 10%, Herba Lysimachiae foenum-graeci quintessence oil 5%, Fructus Mangifera Indicae seed fat 5%, lanoline 2%, Princepia utilis oil 15%.
The preparation method of this Radix Arnebiae (Radix Lithospermi) cold cream comprises the following steps:
1) percent takes following raw material by weight: Chinese medicine composition 15% described in experiment 1, Fructus Maydis oil 20%, Cera Flava 12%, cocoa seed fat 11%, natural tocopherol 5%, Butyrospermum parkii fruit fatty oil 10%, Herba Lysimachiae foenum-graeci quintessence oil 5%, Fructus Mangifera Indicae seed fat 5%, lanoline 2%, Princepia utilis oil 15%.
Step 2) and 3) with embodiment 1.
Embodiment 5
Experiment 1, a kind of Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions, its effective ingredient is with embodiment 4.
The preparation method of this Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions comprises the following steps:
1) take each medical material component: Radix Arnebiae (Radix Lithospermi) 60g, boswellia serrata 25g, Radix Glycyrrhizae 10g, leaf of Herba Rosmarini Officinalis 5g, medical material amounts to 100g;
2) pick: remove in Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis go mouldy, damage by worms, sick scar part, removal of inclusions;
3) pulverize: Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis mixing, coarse crushing is less than 20mm to granularity, then is crushed to pulverulence further, carry out sieving and the powder retaining below 20 orders for following process, obtained mixed-powder;
4) lixiviate: be immersed in by mixed-powder in 1200g white mineral oil, constantly stir in immersion process, soaks 9 hours, obtains lixiviate mixture;
5) ultrasonic extraction: lixiviate mixture is heated to 60 DEG C, open frequency is the ultrasonic Treatment 7 minutes of 20kHz, then stirs 1.5 hours, obtains extraction mixture;
6) filter: extraction mixture filtering accuracy 200 object filter material is filtered, is cooled to room temperature, obtains described Chinese medicine composition.
Experiment 2, a kind of Radix Arnebiae (Radix Lithospermi) cold cream, raw material primarily of following percetage by weight is prepared from: Chinese medicine composition 15% described in experiment 1, Fructus Maydis oil 5%, Cera Flava 5%, cocoa seed fat 5%, natural tocopherol 2.5%, Butyrospermum parkii fruit fatty oil 20%, Herba Lysimachiae foenum-graeci quintessence oil 1%, Fructus Mangifera Indicae seed fat 1%, lanoline 0.5%, Princepia utilis oil 45%.
The preparation method of this Radix Arnebiae (Radix Lithospermi) cold cream comprises the following steps:
1) percent takes following raw material by weight: Chinese medicine composition 15% described in experiment 1, Fructus Maydis oil 5%, Cera Flava 5%, cocoa seed fat 5%, natural tocopherol 2.5%, Butyrospermum parkii fruit fatty oil 20%, Herba Lysimachiae foenum-graeci quintessence oil 1%, Fructus Mangifera Indicae seed fat 1%, lanoline 0.5%, Princepia utilis oil 45%.
Step 2) and 3) with embodiment 1.
Embodiment 6
Detection results on probation is carried out to Radix Arnebiae (Radix Lithospermi) cold cream of the present invention, with the Radix Arnebiae (Radix Lithospermi) cold cream prepared by embodiment 1-5 for experimental group 1-5; Can successfully manage the zicao soft plaster of the various skin problem of infant for matched group 1 with a commercially available declaring, its effective ingredient is prepared from by following raw material: olive oil, Cera Flava, cocoa butter, Semen Tritici aestivi germ oil, Oleum Helianthi, Oleum lavandula angustifolia, Radix Arnebiae extract, tocopherol, soybean oil, canola oil, Semen Maydis oil; Preparing a cold cream not adding Chinese medicine composition is matched group 2.
Its effective ingredient of matched group 2 cold cream is prepared from by the raw material of following weight parts: Fructus Maydis oil 30 parts, 12 parts, Cera Flava, 11 parts, cocoa seed fat, natural tocopherol 5 parts, Butyrospermum parkii fruit fatty oil 10 parts, Herba Lysimachiae foenum-graeci quintessence oil 5 parts, 5 parts, Fructus Mangifera Indicae seed fat, lanoline 2 parts, Princepia utilis oil 20 parts.
The preparation method of matched group 2 cold cream comprises the following steps:
1) following raw material is taken: Fructus Maydis oil 30 parts, 12 parts, Cera Flava, 11 parts, cocoa seed fat, natural tocopherol 5 parts, Butyrospermum parkii fruit fatty oil 10 parts, Herba Lysimachiae foenum-graeci quintessence oil 5 parts, 5 parts, Fructus Mangifera Indicae seed fat, lanoline 2 parts, Princepia utilis oil 20 parts.
2) above-mentioned Fructus Maydis oil, Cera Flava, cocoa seed fat, Butyrospermum parkii fruit fatty oil, Fructus Mangifera Indicae seed fat, lanoline are added in agitated kettle be warming up to 70 DEG C, stirring and dissolving, obtain lysate;
3) lysate is cooled to 50 DEG C, adds tocopherol, Herba Lysimachiae foenum-graeci quintessence oil, Princepia utilis oil, stir, be cooled to 20 DEG C, obtain finished product.
Experiment 1: this experiment determines experimental group 1 ~ 5, the fiducial value (see table 1) of matched group 1 ~ 2 wound repair different times Wound healing rate, the expression value (see table 2) of repair in trauma different times bFGF according to the method for interim " arnebia root oils promotes rabbit wound repair and basic fibroblast growth factor expression " of volume the 1st in [Journal of Chinese Integrative Medicine] January the 4th in 2006.
The fiducial value of table 1 wound repair different times Wound healing rate
| 3 days | 7 days | 14 days | 21 days | |
| Experimental group 1 | 0.17 | 0.35 | 0.32 | 0.27 |
| Experimental group 2 | 0.18 | 0.37 | 0.30 | 0.28 |
| Experimental group 3 | 0.18 | 0.38 | 0.32 | 0.27 |
| Experimental group 4 | 0.20 | 0.41 | 0.35 | 0.31 |
| Experimental group 5 | 0.15 | 0.30 | 0.28 | 0.21 |
| Matched group 1 | 0.10 | 0.28 | 0.25 | 0.16 |
| Matched group 2 | 0.08 | 0.10 | 0.07 | 0.05 |
The expression value of table 2 repair in trauma different times bFGF
| 3 days | 7 days | 14 days | 21 days | |
| Experimental group 1 | 0.6 | 1.4 | 1.1 | 0.3 |
| Experimental group 2 | 0.5 | 1.6 | 1.2 | 0.6 |
| Experimental group 3 | 0.5 | 1.5 | 1.3 | 0.7 |
| Experimental group 4 | 0.7 | 1.8 | 1.5 | 0.9 |
| Experimental group 5 | 0.4 | 0.9 | 0.5 | 0.1 |
| Matched group 1 | 0.3 | 0.7 | 0.3 | 0.1 |
| Matched group 2 | 0.1 | 0.4 | 0.1 | 0.05 |
As shown in Table 1, compare with matched group, the Radix Arnebiae (Radix Lithospermi) cold cream Wound healing rate prepared by embodiment 1 ~ 5 obviously wants high; Radix Arnebiae (Radix Lithospermi) cold cream prepared by embodiment 1 ~ 4 compares with embodiment 5, and the Radix Arnebiae (Radix Lithospermi) skin protection high effect prepared by embodiment 5 is slightly poor, illustrates that the Chinese medicine composition effect that the preferred preparation method of the present invention is extracted is better.
As shown in Table 2, compare with matched group, the expression of the Radix Arnebiae (Radix Lithospermi) cold cream wound tissue bFGF prepared by embodiment 1 ~ 5 all wants high in each period; Radix Arnebiae (Radix Lithospermi) cold cream prepared by embodiment 1 ~ 4 compares with embodiment 5, and the Radix Arnebiae (Radix Lithospermi) skin protection high effect prepared by embodiment 5 is slightly poor, illustrates that the Chinese medicine composition effect that the preferred preparation method of the present invention is extracted is better.
This experimental result shows, the Radix Arnebiae (Radix Lithospermi) cold cream prepared by the embodiment of the present invention 1 ~ 5 can stimulate bFGF to express, and cell division and propagation is accelerated, thus accelerates wound healing.
Experiment 2: infant eczema treatment test
Tested object: the infant suffering from eczema in age 0.5-5 year.Each test group is 25 examples.
Method of testing: the unguentum 3-5 gram that the Radix Arnebiae (Radix Lithospermi) cold cream prepared by every day Example 1 ~ 5, matched group 1 ~ 2 provide is applied to the position of eczema, and repaste once before sleep in the evening, 7 days is a course for the treatment of.
Testing standard: 1. fully recover: eczema disappears; 2. effective: eczema alleviates to a little; 3. effective: eczema alleviates; 4. invalid: eczema is not played a role.
Treatment test effect is in table 3.
Table 3 infant eczema treatment test effect
| Recovery from illness | Effective | Effectively | Invalid | Total effective rate | |
| Experimental group 1 | 16 | 3 | 0 | 6 | 76％ |
| Experimental group 2 | 20 | 0 | 1 | 4 | 84％ |
| Experimental group 3 | 17 | 2 | 2 | 4 | 84％ |
| Experimental group 4 | 21 | 1 | 1 | 2 | 92％ |
| Experimental group 5 | 10 | 5 | 3 | 7 | 72％ |
| Matched group 1 | 2 | 5 | 10 | 8 | 68％ |
| Matched group 2 | 0 | 0 | 8 | 17 | 32％ |
As seen from Table 3, compare with matched group, the Radix Arnebiae (Radix Lithospermi) cold cream prepared by embodiment 1 ~ 5 uses 7 days, and the effect eliminating eczema is relatively obvious; Radix Arnebiae (Radix Lithospermi) cold cream prepared by embodiment 1 ~ 4 compares with embodiment 5, and the Radix Arnebiae (Radix Lithospermi) Radix Arnebiae (Radix Lithospermi) skin protection high effect prepared by embodiment 5 is slightly poor, illustrates that the Chinese medicine composition effect that the preferred preparation technology of the present invention extracts is better.In product test process of the present invention, do not find toxic and side effects, do not find zest.
Embodiment 7
Radix Arnebiae (Radix Lithospermi) cold cream prepared by embodiment 1 ~ 5 is put into respectively 40 DEG C, the environment of room temperature and-15 DEG C, carry out stability test, every 1 week controlled observation 1 time, Continuous Observation 1 month, concrete test result is in table 4.Criterion of acceptability is the abnormal conditions that product does not occur that layering, abnormal flavour, variable color etc. have significant change.
Table 4 stability test record
As shown in Table 4, the Radix Arnebiae (Radix Lithospermi) cold cream prepared by the present invention has good stability.
The above is only preferred embodiment of the present invention, not any restriction is done to the present invention, each technical characteristic of the above embodiment can combine arbitrarily, for making description succinct, the all possible combination of each technical characteristic in above-described embodiment is not all described, but, as long as the combination of these technical characteristics does not exist contradiction, be all considered to be the scope that this description is recorded.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be construed as limiting the scope of the patent.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (10)
1. a Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions, is characterized in that, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 30-70 part, boswellia serrata 15-45 part, Radix Glycyrrhizae 5-15 part, leaf of Herba Rosmarini Officinalis 1-10 part.
2. Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions according to claim 1, it is characterized in that, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 50-60 part, boswellia serrata 25-35 part, Radix Glycyrrhizae 10-15 part, leaf of Herba Rosmarini Officinalis 3-7 part.
3. Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions according to claim 2, is characterized in that, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight parts: Radix Arnebiae (Radix Lithospermi) 60 parts, boswellia serrata 25 parts, 10 parts, Radix Glycyrrhizae, leaf of Herba Rosmarini Officinalis 5 parts.
4. a Radix Arnebiae (Radix Lithospermi) cold cream, is characterized in that, the raw material primarily of following percetage by weight is prepared from:
5. Radix Arnebiae (Radix Lithospermi) cold cream according to claim 4, is characterized in that, the raw material primarily of following percetage by weight is prepared from:
6. Radix Arnebiae (Radix Lithospermi) cold cream according to claim 5, is characterized in that, the raw material primarily of following percetage by weight is prepared from:
7. a preparation method for the Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions described in any one of claim 1-3, is characterized in that, comprise the following steps:
1) pulverize: by Radix Arnebiae (Radix Lithospermi), boswellia serrata, licorice and leaf of Herba Rosmarini Officinalis mixing, pulverize, screening, obtained mixed-powder;
2) processed with honey: mixed-powder is immersed in Mel, then dry obtained processed with honey powder;
3) lixiviate: be immersed in white Limnanthes Alba Seed Oil by processed with honey powder, constantly stir, obtains lixiviate mixture;
4) ultrasonic extraction: heated by lixiviate mixture, by ultrasonic Treatment, stirs, obtains extraction mixture;
5) filter: mixture will be extracted and filter, and be cooled to room temperature, and obtain Chinese medicine composition.
8. the preparation method of Radix Arnebiae (Radix Lithospermi) Skin-care Chinese medicine compositions according to claim 7, is characterized in that, described step 2) in the weight of Mel be the twice of mixed-powder, soak time is 3-5 hour; Described step 3) in the weight of white Limnanthes Alba Seed Oil be the 10-20 of processed with honey powder doubly, soak time is 8-12 hour; Described step 4) in heating-up temperature be 55-65 DEG C, hyperacoustic frequency is 20kHz, and sonication treatment time is 5-10 minute, and mixing time is 1-2 hour.
9. a preparation method for Radix Arnebiae (Radix Lithospermi) cold cream described in any one of claim 4-6, is characterized in that, comprise the following steps:
1) Chinese medicine composition is prepared by method described in any one of claim 7-8;
2) described Fructus Maydis oil, Cera Flava, cocoa seed fat, Butyrospermum parkii fruit fatty oil, Fructus Mangifera Indicae seed fat, lanoline are added agitated kettle, heating, stirring and dissolving, obtains lysate;
3) by lysate lower the temperature, add tocopherol, step 1) described Chinese medicine composition, Herba Lysimachiae foenum-graeci quintessence oil, Princepia utilis oil, stir, cooling, obtain described Radix Arnebiae (Radix Lithospermi) cold cream.
10. the preparation method of Radix Arnebiae (Radix Lithospermi) cold cream according to claim 9, is characterized in that, described step 2) heating-up temperature be 70-80 DEG C; Described step 3) cooling temperature be 45-55 DEG C, chilling temperature is 20-30 DEG C, and described Fructus Maydis oil, Princepia utilis oil are prepared from by milling process.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2591056A1 (en) * | 2016-06-08 | 2016-11-24 | Darong HU ZHOU | Regenerating cosmetic composition (Machine-translation by Google Translate, not legally binding) |
| CN106265346A (en) * | 2016-09-20 | 2017-01-04 | 无比滴（广东）药业有限公司 | A kind of both effectiveness external preparation containing Radix Arnebiae (Radix Lithospermi) extract |
| CN108175738A (en) * | 2018-02-02 | 2018-06-19 | 瑞昌市瑞美化妆品有限公司 | Makeup cosmetic |
| CN108379126A (en) * | 2018-04-26 | 2018-08-10 | 广东岭南职业技术学院 | A kind of fat of Oromaius norvaehollandeae cold cream and preparation method thereof |
| CN111529567A (en) * | 2020-05-12 | 2020-08-14 | 杜世芳 | Traditional Chinese medicine for treating eczema |
| CN113952257A (en) * | 2021-11-23 | 2022-01-21 | 天津和治友德科技发展有限公司 | Active matter combination with multiple effects and application thereof |
| CN114224809A (en) * | 2022-02-18 | 2022-03-25 | 广东蕾琪化妆品有限公司 | Repairing composition, lipstick and preparation method thereof |
| CN115475118A (en) * | 2021-06-16 | 2022-12-16 | 广州悦荟化妆品有限公司 | Cleansing gel with low irritation and skin barrier repairing function and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1226816A (en) * | 1996-08-02 | 1999-08-25 | 普拉姆开米制品股份有限公司 | Oil-in-water emulsion for use on human skin for cleansing, preserving or improving skin condition |
| CN102864045A (en) * | 2012-09-27 | 2013-01-09 | 皖南医学院 | Glittering transparent skincare nutritious soap and preparation method thereof |
-
2015
- 2015-05-21 CN CN201510266590.7A patent/CN104857073B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1226816A (en) * | 1996-08-02 | 1999-08-25 | 普拉姆开米制品股份有限公司 | Oil-in-water emulsion for use on human skin for cleansing, preserving or improving skin condition |
| CN102864045A (en) * | 2012-09-27 | 2013-01-09 | 皖南医学院 | Glittering transparent skincare nutritious soap and preparation method thereof |
Non-Patent Citations (9)
| Title |
|---|
| 侯莲英等: "中药消炎止痒油治疗婴幼儿湿疹的疗效观察", 《遵义医学院学报》 * |
| 冯居秦等主编: "《美容中药学》", 28 February 2015, 中国中医药出版社 * |
| 刘长华等: "甘草油联合湿疹软膏及护理干预在婴幼儿湿疹中的应用", 《吉林医学》 * |
| 彭怀仁主编: "《中药方剂大辞典 第三册》", 30 November 1994, 人民卫生出版社 * |
| 王建新主编: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
| 罗布曲珍: "紫草酥油膏在皮肤外科中的应用", 《西藏医药杂志》 * |
| 艾儒棣等主编: "《当代中医皮肤科临床家丛书》", 31 October 2014, 中国医药科技出版社 * |
| 裴宪武等: "紫草油剂促进兔创面修复及碱性成纤维细胞生长因子表达", 《中西医结合学报》 * |
| 赵静: "紫草油外涂治疗小儿渗出型湿疹46例疗效观察与护理", 《中国医学创新》 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2591056A1 (en) * | 2016-06-08 | 2016-11-24 | Darong HU ZHOU | Regenerating cosmetic composition (Machine-translation by Google Translate, not legally binding) |
| CN106265346A (en) * | 2016-09-20 | 2017-01-04 | 无比滴（广东）药业有限公司 | A kind of both effectiveness external preparation containing Radix Arnebiae (Radix Lithospermi) extract |
| CN108175738A (en) * | 2018-02-02 | 2018-06-19 | 瑞昌市瑞美化妆品有限公司 | Makeup cosmetic |
| CN108379126A (en) * | 2018-04-26 | 2018-08-10 | 广东岭南职业技术学院 | A kind of fat of Oromaius norvaehollandeae cold cream and preparation method thereof |
| CN111529567A (en) * | 2020-05-12 | 2020-08-14 | 杜世芳 | Traditional Chinese medicine for treating eczema |
| CN115475118A (en) * | 2021-06-16 | 2022-12-16 | 广州悦荟化妆品有限公司 | Cleansing gel with low irritation and skin barrier repairing function and preparation method thereof |
| CN113952257A (en) * | 2021-11-23 | 2022-01-21 | 天津和治友德科技发展有限公司 | Active matter combination with multiple effects and application thereof |
| CN114224809A (en) * | 2022-02-18 | 2022-03-25 | 广东蕾琪化妆品有限公司 | Repairing composition, lipstick and preparation method thereof |
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Address after: 219 1320D, five Zhongshan Road, Yuexiu District, Guangdong, Guangzhou, 510000 Patentee after: Guangzhou xiaobee Biotechnology Co., Ltd Address before: 219 1320D, five Zhongshan Road, Yuexiu District, Guangdong, Guangzhou, 510000 Patentee before: GUANGZHOU XIAOMIFENG BIOLOGICAL TECHNOLOGY Co.,Ltd. |