CN104856176A - 一种治疗黄褐斑的饮料 - Google Patents
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Abstract
本发明所以饮料领域，公开了一种治疗黄褐斑的饮料，由下述重量份的中药提取制备而成：长青草15份、绿豆升麻12份、荷莲豆草18份、肥皂荚12份、芭蕉头20份，能治疗黄褐斑。
Description
技术领域
本发明涉及一种饮料，尤其涉及一种治疗黄褐斑的饮料。
背景技术
黄褐斑是一种令中青年妇女烦恼的色素增生性皮肤病。它的主要表现是面部皮肤出现大小不等、形状不一的色素斑，颜色多为淡褐色、黄褐色，也有咖啡色或淡黑色。一般是对称地分布在眼周围附近、额部、颧颊部、鼻旁和口唇周围，边界清楚，表面皮肤光滑，不痛不痒，没有皮屑。目前治疗产品黄褐斑的效果都不太好，因此急需一种治疗黄褐斑的中药。
发明内容
发明目的：本发明的目的在于提供一种治疗黄褐斑的饮料及其制备方法。
技术方案：
一种治疗黄褐斑的饮料，由下述重量份的中药提取制备而成：长青草15份、绿豆升麻12份、荷莲豆草18份、肥皂荚12份、芭蕉头20份。
所述治疗黄褐斑的饮料，制备方法：取上述中药，加水煎煮2次，每次加药材重量10倍量的水，每次煎煮2小时，合并煎液，浓缩到摄氏65度时相对密度为1.1，加乙醇至醇浓度为65％，静止48小时，过滤，浓缩到摄氏65度时相对密度为1.2，加水，灭菌，制成饮料。
所述治疗黄褐斑的饮料在制备治疗黄褐斑饮料中的应用。
长青草为黄杨科粉蕊黄杨属植物顶蕊三角咪Pachysandra terminalis Sieb.et Zucc.，以全草入药。全年可采，洗净切段，晒干。祛风止咳，舒筋活络，调经止带。用于慢性气管炎，风湿性关节炎，小腿转筋，白带，闭经，精神病烦燥不安。
绿豆升麻为毛茛科类叶升麻属植物类叶升麻Actaea asiatica Hara，以根状茎及全草入药。秋季采集，分别晒干。清肺止咳，清热解毒。用于感冒头痛，百日咳。外用治犬咬伤。本发明采用全草入药。
荷莲豆草为荷莲豆草属植物荷莲豆草Drymaria diandra Blume[D.cordata auct.non(L.)Willd.]的全草。夏秋采，洗净鲜用或晒干。清热解毒，利尿通便，活血消肿，退翳。用于急性肝炎，胃痛，疟疾，翼状胬肉，腹水，便秘；外用治骨折，疮痈，蛇咬伤。
肥皂荚，拉丁名为Gymnocladus chinensis Baill，是一种落叶乔木，无刺，高达5-12米；树皮灰褐色且有白色皮孔，二回偶数羽状复叶，无托叶，叶轴有槽，被面有短柔毛，几乎无叶柄。花杂性，为白色或带紫色，有长梗，向下垂。荚果长圆形，扁平或膨胀，无毛，有种子2-4颗，种子近球形而稍扁，黑色，平滑无毛。一般8月间结果。分布于江苏、浙江、江西、安徽、福建、湖北、湖南、广东、广西、四川等省区。生于海拔150-1500米山坡、山腰、杂木林中，果含有胰皂素，可洗涤丝绸，亦可入药。种子油可作油漆等工业用油，祛风除湿，活血消肿。用于风湿疼痛，跌打损伤，疔疮肿毒。本发明以果实入药。
芭蕉头为芭蕉科芭蕉属植物芭蕉Musa basjoo Sieb et Zucc.，以根、茎和花入药。根及茎四季可采，洗净鲜用或晒干；夏秋采花蕾，多鲜用。清热解毒，利尿消肿，凉血，止痛。用于感冒咳嗽，头痛，高血压病，胃痛，腹痛，肝炎，痢疾，崩漏，胎动不安，尿路感染，水肿；外用治中耳炎，创伤出血，痈疖肿毒。本发明以根入药。
有益效果：本发明长青草、绿豆升麻调经止带、清热解毒为君药，荷莲豆草、肥皂荚活血消肿为臣药，芭蕉头清热解毒为佐使药，全方治疗黄褐斑，效果良好。
具体实施方式
实施例1：取长青草15g、绿豆升麻12g、荷莲豆草18g、肥皂荚12g、芭蕉头20，加水煎煮2次，每次加药材重量10倍量的水，每次煎煮2小时，合并煎液，浓缩到摄氏65度时相对密度为1.1，加乙醇至醇浓度为65％，静止48小时，过滤，浓缩到摄氏65度时相对密度为1.2，加水，灭菌，制成饮料，每瓶200ml。
实施例2：本发明治疗黄褐斑的临床资料
临床药物：按上述实施例1制备本发明饮料，口服，一次200ml，一日3次。
临床观察50例患者，参照《中药新药临床研究指导原则》，纳入标准：1.年龄在18岁-60岁之间，女性。2.无感染、对本药不过敏、无精神异常者。符合黄褐斑的诊断标准(中国中西医结合学会皮肤性病专业委员会色素病学组黄褐斑的临床诊断与疗效标准(2003年修订稿))。3.排除其他皮肤病和过敏性疾病：对本药无刺激、不过敏者。治疗前未用过同类药品者，且无正在进行其他同类药物试验者。4.符合黄褐斑的诊断标准和纳入标准的知情志愿患者；完成知情同意及相关告知者。
排除标准：1.不符合黄褐斑的诊断和纳入标准；不符合黄褐斑的纳入标准；2.有合并感染、对本药过敏、精神异常。3.根据研究者判断，具有降低入组可能性或使入组复杂化的其他病史，如工作环境经常变动，容易造成失访的情况；或正在参加其他药物临床研究的受试者。
治疗方法：服用本发明饮料一月。嘱患者治疗期间保持心情舒畅，避免过分忧虑和过劳，并尽量避免日光照射，少食酱油、酱菜、烟、酒、咖啡等含色素的食物，忌食辛辣食物。
疗效观察：疗效标准参照《中药新药临床研究指导原则》。基本治愈：①肉眼视色斑面积消退大于90％，颜色基本消失，1米距离肉眼看不见明显的斑点。②评分法计算治疗后下降指数≥0.8。显效：①肉眼视色斑面积消退大于60％，颜色明显变淡。②评分法计算治疗后下降指数≥0.5。好转：①肉眼视色斑面积消退大于30％，颜色变淡。②评分法计算治疗后下降指数≥0.3。无效：①肉眼视色斑面积消退小于30％，颜色变化不明显。②评分法计算治疗后下降指数≥0。
计算公式(尼莫地平法)：[(治疗前积分-治疗后积分)/治疗前积分]×100％。
治疗结果：50例均于1个疗程结束后立即进行复查。结果：治愈8例，显效13例，有效25例，无效4例，总有效率92％。
Claims (3)
1.一种治疗黄褐斑的饮料，其特征在于，由下述重量份的中药提取制备而成：长青草15份、绿豆升麻12份、荷莲豆草18份、肥皂荚12份、芭蕉头20份。
2.如权利要求1所述治疗黄褐斑的饮料，其特征在于，制备方法：取上述中药，加水煎煮2次，每次加药材重量10倍量的水，每次煎煮2小时，合并煎液，浓缩到摄氏65度时相对密度为1.1，加乙醇至醇浓度为65％，静止48小时，过滤，浓缩到摄氏65度时相对密度为1.2，加水，灭菌，制成饮料。
3.如权利要求1所述治疗黄褐斑的饮料在治疗黄褐斑饮料中的应用。
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| CN108041368A (zh) * | 2017-11-20 | 2018-05-18 | 宁国平衡健康管理有限公司 | 一种改善黄褐斑的宣木瓜饮料 |
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| 尤玉如: "《乳品与饮料工艺学》", 31 March 2014, 中国轻工业出版社 * |
| 钟宏量: "自拟祛斑饮治疗黄褐斑疗效观察", 《广西中医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108041368A (zh) * | 2017-11-20 | 2018-05-18 | 宁国平衡健康管理有限公司 | 一种改善黄褐斑的宣木瓜饮料 |
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