CN104853746B - 用于治疗红斑痤疮的组合物 - Google Patents

用于治疗红斑痤疮的组合物 Download PDF

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Publication number
CN104853746B
CN104853746B CN201280077293.2A CN201280077293A CN104853746B CN 104853746 B CN104853746 B CN 104853746B CN 201280077293 A CN201280077293 A CN 201280077293A CN 104853746 B CN104853746 B CN 104853746B
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China
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composition
alcohol
weight
oil
group
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CN201280077293.2A
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Chinese (zh)
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CN104853746A (zh
Inventor
哈南·塞尔特库克
奥弗·托莱达诺
哈伊姆·巴尔-西曼托夫
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Sol Gel Technologies Ltd
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Sol Gel Technologies Ltd
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Priority to CN201810145665.XA priority Critical patent/CN108159425A/zh
Publication of CN104853746A publication Critical patent/CN104853746A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/327Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201280077293.2A 2012-11-27 2012-11-27 用于治疗红斑痤疮的组合物 Active CN104853746B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810145665.XA CN108159425A (zh) 2012-11-27 2012-11-27 用于治疗红斑痤疮的组合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IL2012/050479 WO2014083557A1 (en) 2012-11-27 2012-11-27 Compositions for the treatment of rosacea

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201810145665.XA Division CN108159425A (zh) 2012-11-27 2012-11-27 用于治疗红斑痤疮的组合物

Publications (2)

Publication Number Publication Date
CN104853746A CN104853746A (zh) 2015-08-19
CN104853746B true CN104853746B (zh) 2018-02-23

Family

ID=47428789

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201280077293.2A Active CN104853746B (zh) 2012-11-27 2012-11-27 用于治疗红斑痤疮的组合物
CN201810145665.XA Pending CN108159425A (zh) 2012-11-27 2012-11-27 用于治疗红斑痤疮的组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201810145665.XA Pending CN108159425A (zh) 2012-11-27 2012-11-27 用于治疗红斑痤疮的组合物

Country Status (7)

Country Link
EP (1) EP2925296B1 (https=)
JP (1) JP6423355B2 (https=)
CN (2) CN104853746B (https=)
CA (2) CA2889199C (https=)
ES (1) ES2861431T3 (https=)
MX (1) MX376183B (https=)
WO (1) WO2014083557A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017068673A1 (ja) * 2015-10-21 2017-04-27 マルホ株式会社 皮膚用の医薬組成物
AU2017229125B2 (en) 2016-03-08 2021-07-29 Living Proof, Inc. Long lasting cosmetic compositions
EP3651756B1 (en) * 2017-07-12 2025-09-03 Sol-Gel Technologies Ltd. Compositions comprising encapsulated tretinoin
EP3681921A2 (en) 2017-09-13 2020-07-22 Living Proof, Inc. Color protectant compositions
AU2018333932B2 (en) 2017-09-13 2024-05-02 Living Proof, Inc. Long lasting cosmetic compositions
CN111356501A (zh) 2017-11-20 2020-06-30 生活实验公司 实现持久化妆品性能的属性
BR112020021902B1 (pt) 2018-04-27 2024-02-20 Living Proof, Inc Composições cosméticas de poliuretano-ureia para tratamento capilar, método de preservação da ondulação no cabelo humano e os usos de poliuretano-ureia
EP3586849A1 (en) * 2018-06-29 2020-01-01 Aprofol AG Folate preparations
JP6811213B2 (ja) * 2018-07-03 2021-01-13 ソル − ゲル テクノロジーズ リミテッド 酒さの治療のための組成物
US20200261395A1 (en) 2019-02-19 2020-08-20 Sol-Gel Technologies Ltd. Method for treatment of rosacea

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008093346A2 (en) * 2007-02-01 2008-08-07 Sol-Gel Technologies Ltd. Compositions for topical application comprising a peroxide and retinoid
CN101605537A (zh) * 2006-11-28 2009-12-16 盖尔德马研究及发展公司 含有过氧化苯甲酰、至少一种萘甲酸的衍生物和至少一种聚氨酯聚合物类型的化合物或其衍生物的组合物及其用途
WO2012037000A1 (en) * 2010-09-15 2012-03-22 Norac, Pharma Benzoyl peroxide composition, methods of making same, and pharmaceutical or cosmetic formulations comprising same, and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1335693A2 (en) * 2000-04-21 2003-08-20 Sol-Gel Technologies Ltd. Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
GB0301577D0 (en) * 2003-01-23 2003-02-26 Edko Pazarlama Tanitim Ltd Sti Topical pharmaceutical and/or cosmetic dispense systems
FR2886850B1 (fr) 2005-06-10 2007-10-05 Galderma Sa Composition a base d'une avermectine et de peroxyde de benzoyle notamment pour le traitement de la rosacee
WO2008057411A1 (en) * 2006-11-02 2008-05-15 Stiefel Laboratories, Inc. Kits containing benzoyl peroxide pads and another acne-treating composition, and formulations and methods of use therefor
FR2910320B1 (fr) * 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
AU2008211554B2 (en) * 2007-02-01 2013-12-19 Sol-Gel Technologies Ltd. Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
KR101538187B1 (ko) * 2007-11-30 2015-07-22 갈데르마 리써어치 앤드 디벨로프먼트 하나 이상의 나프토산 유도체, 과산화 벤조일 및 하나 이상의 필름-형성제를 함유하는 조성물
CA2723029C (en) * 2008-06-05 2016-07-19 Dow Pharmaceutical Sciences, Inc. Topical pharmaceutical formulations containing a low concentration of benzoyl peroxide in suspension in water and a water-miscible organic solvent
CN102112219A (zh) * 2008-07-31 2011-06-29 溶胶凝胶技术公司 包含有效成分和金属氧化物壳的微胶囊,其制备方法及其用途
MX2011005010A (es) * 2009-01-05 2011-05-30 Sol Gel Technologies Ltd Composiciones topicas que contienen agentes activos recubiertos.
JP5784619B2 (ja) * 2009-10-21 2015-09-24 ドウ ファーマシューティカル サイエンシーズ、インク. 過酸化ベンゾイルを含む粉末を湿潤させるための方法
BR112012012023A2 (pt) * 2009-12-31 2016-05-17 Sol Gel Technologies Ltd processo para preparar microcápsulas, microcápsulas, composição, método para tratar uma condição superficial em um indivíduo, e, uso das microcápsulas

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101605537A (zh) * 2006-11-28 2009-12-16 盖尔德马研究及发展公司 含有过氧化苯甲酰、至少一种萘甲酸的衍生物和至少一种聚氨酯聚合物类型的化合物或其衍生物的组合物及其用途
WO2008093346A2 (en) * 2007-02-01 2008-08-07 Sol-Gel Technologies Ltd. Compositions for topical application comprising a peroxide and retinoid
WO2012037000A1 (en) * 2010-09-15 2012-03-22 Norac, Pharma Benzoyl peroxide composition, methods of making same, and pharmaceutical or cosmetic formulations comprising same, and uses thereof

Also Published As

Publication number Publication date
JP6423355B2 (ja) 2018-11-14
MX2015005515A (es) 2015-07-17
EP2925296A1 (en) 2015-10-07
CA2889199C (en) 2020-05-19
WO2014083557A1 (en) 2014-06-05
JP2016501205A (ja) 2016-01-18
MX376183B (es) 2025-03-07
EP2925296B1 (en) 2021-01-06
CN104853746A (zh) 2015-08-19
CA3051403A1 (en) 2014-06-05
CN108159425A (zh) 2018-06-15
CA3051403C (en) 2021-07-20
ES2861431T3 (es) 2021-10-06
CA2889199A1 (en) 2014-06-05

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