CN104840521A - Pharmaceutical composition for treating rhinitis - Google Patents
Pharmaceutical composition for treating rhinitis Download PDFInfo
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- CN104840521A CN104840521A CN201510298670.0A CN201510298670A CN104840521A CN 104840521 A CN104840521 A CN 104840521A CN 201510298670 A CN201510298670 A CN 201510298670A CN 104840521 A CN104840521 A CN 104840521A
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Abstract
The invention discloses a pharmaceutical composition for treating rhinitis. According to the parts by weight, the raw material components are as follows: 30-40 parts of agastache rugosus, 45-65 parts of small centipeda herb, 15-30 parts of ossa draconis, 15-30 parts of radix angelicae, 20-40 parts of magnolia flower, 4-6 parts of borneol, 0.09-0.12 part of chlortrimeton and 30-50 parts of cocklebur fruit. The traditional Chinese medicine raw materials mentioned above are matched reasonably, and the given composition proportion enables the raw materials to play a very good synergistic effect and have effects of dredging orifices, dissipating wet, dispelling the wind, diminishing swelling and clearing the nasal passage; and the traditional Chinese medicine raw materials after being combined together have an outstanding effect in the aspect of treating rhinitis.
Description
Technical field:
The present invention relates to Chinese medicine and western medicine field, specifically a kind of pharmaceutical composition for the treatment of rhinitis.
Background technology:
Rhinitis (containing sinusitis, allergic rhinitis) is the nasal membrane infectious disease caused by a kind of heresy invasion because of lung, spleen, suffer from a deficiency of the kidney weak, wind and cold or wind heat.Clinical be cardinal symptom with ictal nasal obstruction, rhinocnesmus, sneeze, watery nasal discharge headache and dizzy, hypomnesis and concha nasalis enlargement a kind of commonly encountered diseases, frequently-occurring disease.At present, the medicine and the method that market are used for the treatment of rhinitis are a lot, but there is certain limitation in varying degrees.
Summary of the invention:
The present invention is directed to above existing issue and provide a kind of pharmaceutical composition for the treatment of rhinitis, this pharmaceutical composition medicine take natural Chinese medicines as main developing, determined curative effect and having no side effect, and has significant effect to treatment rhinitis.
To achieve these goals, present invention employs following technical scheme:
Treat a pharmaceutical composition for rhinitis, by weight, raw material components is as follows: Herba Pogostemonis 30-40 part, Herba Centipedae 45-65 part, Os Draconis 15-30 part, Radix Angelicae Dahuricae 15-30 part, Flos Magnoliae 20-40 part, Borneolum Syntheticum 4-6 part, chlorphenamine 0.09-0.12 part, Fructus Xanthii 30-50 part.
Preferably, by weight, raw material components is as follows: Herba Pogostemonis 30 parts, Herba Centipedae 50 parts, Os Draconis 20 parts, the Radix Angelicae Dahuricae 20 parts, Flos Magnoliae 30 parts, Borneolum Syntheticum 5 parts, chlorphenamine 0.1 part, Fructus Xanthii 40 parts.
In the middle of pharmaceutical composition of the present invention, the pharmacology analysis of each crude drug is as follows:
Herba Pogostemonis: pungent, tepor.Return spleen, stomach, lung meridian.Eliminating turbid pathogen with aromatics, and middle preventing or arresting vomiting, deliver expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is vomitted, heat-damp in summer exterior syndrome, hygropyrexia from the beginning of, heating asthenia, uncomfortable in chestly do not relax, cold-damp closes summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.Herba Pogostemonis has sterilizing function, and sucking a leaf can antihalitosis, keeps off infection, and can be used as antiseptic.
Herba Centipedae: be the herb of Compositae annual herb phytobezoar Herba Coriandri.Acrid in the mouth, warm in nature.Have sensible wet dissipation, detumescence of dispeling the wind, stuffy nose relieving profit key, the merit of improving eyesight removing nebula.
Os Draconis: there is following effect: 1. astringing intestine to stop diarrhea only profit: sliding for asthenia of the large intestine, chronic diarrhea is more than, proctoptosis.2. QI invigorating arresting sweating: not solid for heart deficiency of kidney-QI, the floating inducing vomiting sweating of empty sun, the symptom of common vexed cardiopalmus and heating.3. granulation promoting close skin ulcer: for umbilical sore, acute appendicitis, interior infantile malnutrition and incised wound hemorrhage, do not close up for a long time.4. subduing hyperactive YANG to ease mental disorders: more floating for liver-yang, mania and irritation delirium, dreaminess is had a sleepless night, and cardiopalmus is moved cautious, coma, and infantile convulsion is twitched.5. hold back blood hemostasis: for hematemesis and epistaxis, hemorrhage in ear, hematuria, wound hemorrhage, bleeding not during menses etc.Controlling nocturnal emission with astringent drugs is only lost: for nocturnal emission of working with one's mind, sleep and namely let out essence.
The Radix Angelicae Dahuricae: dispel the wind, dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Flos Magnoliae: have another name called flos magnoliae, Flos Jasmini Nudiflori is the alabastrum of Magnoliaceae defoliation bush plant Flos Magnoliae.Acrid in the mouth warm in nature, returns lung, stomach footpath.Because its pungent loose temperature is led to, fragrance is walked to alter, up women's head-ornaments, and kind clearing the nasal passage, because controlling nasosinusitis headache key medicine.
Borneolum Syntheticum: have another name called sheet brain, Fructus Citri tangerinae sheet, Borneolum Syntheticum, MEIHUA BINGPIAN, Dipterocarpus pilosus, Flos Mume brain, Borneolum Syntheticum brain, Mei Bing etc., for translucent like the crystalline solid of Flos Mume lobe bulk, lamellar.Borneolum Syntheticum is resin and the volatile oil of Spore density Borneolum Syntheticum.Have many effects and effect, can be used for treatment excess syndrome of stroke coma, conjunctival congestion and swelling pain, sore throat aphtha, skin infection swell and ache.
Chlorphenamine: can treatment of allergic rhinitis, the nasal congestion caused allergic rhinitis and upper respiratory tract infection is effective, can be used for flu or sinusitis; Mucocutaneous allergy; All effective to urticaria, pollinosis, vasomotor rhinitis, and skin pruritus caused by insect bite and edema can be alleviated; Also can be used for controlling drug eruption and contact dermatitis, but must stop using or avoid simultaneously to contact sensitizing drugs.
Fructus Xanthii: there is dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, antipruritic effect.Can be used for treatment lumbago and skelalgia, allergic rhinitis, chronic rhinitis, malaria, parotitis, ulcer of the lower limb etc.
Said medicine combination makes each efficacy of drugs produce synergism, all medicines and use in side, play sensible wet dissipation altogether, detumescence of dispeling the wind, stuffy nose relieving profit key effect, jointly reach and treat the object of rhinitis.
The invention has the beneficial effects as follows:
Above-mentioned various raw material of Chinese medicine carries out reasonably combined by the present invention, and the composition proportion provided makes each raw material serve good synergism, there is sensible wet dissipation, detumescence of dispeling the wind, stuffy nose relieving profit key effect, combine Be very effective in treatment rhinitis.Compared with prior art, the present invention more optimizes, and has no adverse reaction, and safety is very high; The property of medicine relaxes, and without the need to for oral administration, can not cause drug dependence, can long-term relieved use.
Detailed description of the invention:
Below in conjunction with embodiment, the present invention is described in detail, but do not form limiting the scope of the invention.
Embodiment 1:
Treat a pharmaceutical composition for rhinitis, by weight, raw material components is as follows: Herba Pogostemonis 30 parts, Herba Centipedae 50 parts, Os Draconis 20 parts, the Radix Angelicae Dahuricae 20 parts, Flos Magnoliae 30 parts, Borneolum Syntheticum 5 parts, chlorphenamine 0.1 part, Fructus Xanthii 40 parts.
The preparation method of the pharmaceutical composition of described treatment rhinitis: above-mentioned each raw material medicaments in part by weight taken, mixing, grinds to the powder altogether, crosses 120 mesh sieves, and bottling sealing is for subsequent use, to obtain final product.
The using method of this pharmaceutical composition is: first clean nasal cavity with the boric acid powder that concentration after dilution is 3% during use, then dip in pharmaceutical composition powder of the present invention with sterilized cotton ball, be applied to nasal cavity affected part, every day 2-3 time.
Embodiment 2:
Treat a pharmaceutical composition for rhinitis, by weight, raw material components is as follows: Herba Pogostemonis 30 parts, Herba Centipedae 45 parts, Os Draconis 15 parts, the Radix Angelicae Dahuricae 15 parts, Flos Magnoliae 20 parts, Borneolum Syntheticum 4 parts, chlorphenamine 0.09 part, Fructus Xanthii 30 parts.
Its preparation method and using method are with embodiment 1.
Embodiment 3:
Treat a pharmaceutical composition for rhinitis, by weight, raw material components is as follows: Herba Pogostemonis 40 parts, Herba Centipedae 65 parts, Os Draconis 30 parts, the Radix Angelicae Dahuricae 30 parts, Flos Magnoliae 40 parts, Borneolum Syntheticum 6 parts, chlorphenamine 0.12 part, Fructus Xanthii 50 parts.
Its preparation method and using method are with embodiment 1.
Embodiment 4:
Treat a pharmaceutical composition for rhinitis, by weight, raw material components is as follows: Herba Pogostemonis 35 parts, Herba Centipedae 60 parts, Os Draconis 25 parts, the Radix Angelicae Dahuricae 25 parts, Flos Magnoliae 30 parts, Borneolum Syntheticum 5 parts, chlorphenamine 0.11 part, Fructus Xanthii 38 parts.
Its preparation method and using method are with embodiment 1.
Embodiment 5:
Treat a pharmaceutical composition for rhinitis, by weight, raw material components is as follows: Herba Pogostemonis 32 parts, Herba Centipedae 58 parts, Os Draconis 26 parts, the Radix Angelicae Dahuricae 22 parts, Flos Magnoliae 33 parts, Borneolum Syntheticum 5 parts, chlorphenamine 0.09 part, Fructus Xanthii 42 parts.
Its preparation method and using method are with embodiment 1.
Curative effect is investigated
1. diagnosis basis
Diagnostic criteria with reference to rhinitis in " Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine issues:
There are more than 2 (containing 2) in the symptoms such as clinical symptoms sneeze, clear water sample tears, nasal obstruction, rhinocnesmus, every day Symptoms last or be accumulated at more than 1 hour.Can with the eye symptom such as ophthalmic pruritus, conjunctival congestion.The common nasal mucosa of sign is pale, edema, nasal cavity watery secretion.Skin prick test is positive, and/or Specificity IgE is positive, feasible nasal provocation test if desired.
2. ordinary circumstance
For checking therapeutic effect of the present invention, choosing 150 routine rhinitis persons and giving above-described embodiment obtained medicine composite for curing.Wherein male 93 example, women 57 example, age 16-70 year, 42 years old mean age.Course of disease 0.5-25, average 10 years.
3. curative effect determinate standard
(1) clinical symptoms, sign disappear or substantially disappear for curing;
(2) clinical symptoms, sign are obviously improved or are made moderate progress as effectively;
(3) clinical symptoms, sign are all not improved or increase the weight of as invalid.
4. result
150 routine rhinitis persons cure 90 examples, cure rate 60% after using pharmaceutical composition 2-5 of the present invention course for the treatment of; Effective 51 examples, effective percentage 34%; No effect 9, inefficiency 6%.Total effective rate is 94%.
5. side effect
Do not find any toxic and side effects.
Model case:
Lee, man, 43 years old.Patient suffers from more than 20 years of sinusitis, often rhinocnesmus, snivel, sneeze.The unexpected exacerbation of symptoms of in JIUYUE, 2014, sneeze is paid no attention to disconnected continuously, and nasal obstruction also increases the weight of, and need mouth breathing, falling asleep evening, it is awake also to suppress, impact life and rest, cisco unity malfunction.Various Therapeutic Method through 3 months are attempted, and curative effect is still not good enough.Patient suffers untold misery.Give medicine composite for curing of the present invention, after treating 1 course for the treatment of, patient's sneeze number of times obviously reduces, and nasal obstruction alleviates, and evening, sleep was no longer suppressed awake, can have a rest well.1 course for the treatment of of continual cure, patient's symptom of having a stuffy nose is alleviated substantially, and sneeze obviously alleviates, and only beats several sneeze when returning in room from open air.2 courses for the treatment of of continual cure again, patient's nasal obstruction, sneeze, symptom complete incidence graph, snivel disappears substantially, can normally work and have a rest, and obtains recovery from illness.Follow up a case by regular visits to and have no recurrence in 2 years.
Huang, female, 18 years old.Suffer from allergic rhinitis 3 years, nasal obstruction rhinocnesmus, sneeze, drops tears, rhinorrhea, dizzy feeling of fullness in the head, and morbidity in spring of being everlasting, hyposmia, has obvious pollen hypersensitivity symptom.Since patient idiopathy, anemophobia is afraid of cold, listlessness, hypomnesis, poor sleep.Through treatments such as Chinese medicine, Western medicine and nasal cavity injections, bad during symptom fashion, have repeatedly more.Use 2 courses for the treatment of of pharmaceutical composition of the present invention, symptom is obviously improved, and continues 2 courses for the treatment of of use, transference cure.Follow up a case by regular visits to after 2 years without recurrence.
Claims (2)
1. treat a pharmaceutical composition for rhinitis, it is characterized in that, by weight, raw material components is as follows: Herba Pogostemonis 30-40 part, Herba Centipedae 45-65 part, Os Draconis 15-30 part, Radix Angelicae Dahuricae 15-30 part, Flos Magnoliae 20-40 part, Borneolum Syntheticum 4-6 part, chlorphenamine 0.09-0.12 part, Fructus Xanthii 30-50 part.
2. as claim 1 treats the pharmaceutical composition of rhinitis, it is characterized in that, by weight, raw material components is as follows: Herba Pogostemonis 30 parts, Herba Centipedae 50 parts, Os Draconis 20 parts, the Radix Angelicae Dahuricae 20 parts, Flos Magnoliae 30 parts, Borneolum Syntheticum 5 parts, chlorphenamine 0.1 part, Fructus Xanthii 40 parts.
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| CN201510298670.0A CN104840521A (en) | 2015-06-03 | 2015-06-03 | Pharmaceutical composition for treating rhinitis |
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| CN201510298670.0A CN104840521A (en) | 2015-06-03 | 2015-06-03 | Pharmaceutical composition for treating rhinitis |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168654A (en) * | 2015-09-21 | 2015-12-23 | 江志鑫 | Medicine composition for treating chronic simple rhinitis |
| CN108403863A (en) * | 2018-05-04 | 2018-08-17 | 杨伟东 | A kind of nose speed health preparation for treating rhinitis |
| CN110448674A (en) * | 2019-08-16 | 2019-11-15 | 河南壹哆康健康科技有限公司 | For treating concha hypertrophy, powder of nasal polyp and preparation method thereof |
| CN111297994A (en) * | 2020-02-27 | 2020-06-19 | 广东省惠州市中药厂有限公司 | Nose comforting tablet and preparation method and using method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101700280A (en) * | 2009-11-11 | 2010-05-05 | 丁常燕 | Traditional Chinese medicine for treating allergic rhinitis |
| CN102258574A (en) * | 2011-07-13 | 2011-11-30 | 山东省立医院 | Chinese medicinal preparation for treating allergic rhinitis |
-
2015
- 2015-06-03 CN CN201510298670.0A patent/CN104840521A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101700280A (en) * | 2009-11-11 | 2010-05-05 | 丁常燕 | Traditional Chinese medicine for treating allergic rhinitis |
| CN102258574A (en) * | 2011-07-13 | 2011-11-30 | 山东省立医院 | Chinese medicinal preparation for treating allergic rhinitis |
Non-Patent Citations (1)
| Title |
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| 徐三文等: "《新编中国五官科秘方全书》", 30 September 2004, 科学技术文献出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168654A (en) * | 2015-09-21 | 2015-12-23 | 江志鑫 | Medicine composition for treating chronic simple rhinitis |
| CN108403863A (en) * | 2018-05-04 | 2018-08-17 | 杨伟东 | A kind of nose speed health preparation for treating rhinitis |
| CN110448674A (en) * | 2019-08-16 | 2019-11-15 | 河南壹哆康健康科技有限公司 | For treating concha hypertrophy, powder of nasal polyp and preparation method thereof |
| CN111297994A (en) * | 2020-02-27 | 2020-06-19 | 广东省惠州市中药厂有限公司 | Nose comforting tablet and preparation method and using method thereof |
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Application publication date: 20150819 |
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