CN104840485A - Active carbon suppository for treating cervical erosion, and preparation method thereof - Google Patents
Active carbon suppository for treating cervical erosion, and preparation method thereof Download PDFInfo
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- CN104840485A CN104840485A CN201510196839.1A CN201510196839A CN104840485A CN 104840485 A CN104840485 A CN 104840485A CN 201510196839 A CN201510196839 A CN 201510196839A CN 104840485 A CN104840485 A CN 104840485A
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Abstract
The invention relates to an active carbon suppository for treating cervical erosion, and a preparation method thereof. The suppository is composed of a suppository particle and a medical absorbent gauze wrapped outside the suppository particle; the suppository particle is composed of a medicinal active carbon fiber (ACF), carbomer, sodium carboxymethyl cellulose, mixed fatty glyceride, gelatin, glycerin and purified water, and is used for treating colpitis and other gynecological inflammations. The active carbon suppository can adsorb various pathogenic bacteria and viruses into fiber holes to change the survival environment of the bacteria and the viruses in order to make the bacteria and the viruses dead, so anti-inflammation, pain relieving, haemostasis, deodorizing and disinfection effects are reached, the cell growth is promoted, the tissue regeneration is accelerated, the normal internal environment is not destroyed, the growth of lactic acid bacillus is not influenced, the bacteria do not have drug resistance, and the suppository has the advantages of stable antibacterial stability, wide antibacterial spectrum, use convenience, comfortableness, no pollution, definite therapeutic effect, good patient compliance, and clinic mass application.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of active carbon suppository for the treatment of cervical erosion and preparation method thereof.
Background technology
Vaginitis is the inflammation of vaginal mucosa, is the common disease of Out-patient Clinic of Department of Gynecology.Normal healthy women, due to anatomy and biochemical characteristics, the intrusion of vagina to pathogen has nature defense function, and when the natural defense function of vagina is destroyed, then pathogen is easy to invade, and causes colpitis.At present according to the incomplete statistics of World Health Organization (WHO), in women, various gynaecopathia sickness rate is more than 65%, China's interrelated data investigation display, and women of child-bearing age's gynaecopathia sickness rate is more than 70%, and women almost 100% suffers from different vaginosiss in life.Colpitic main clinical manifestation is leucorrhoea grow in quantity, vulvovaginal pruritus, pudendum redness, abnormal flavour etc., and Therapeutic Method is the vagina antibiotic of being correlated with or Chinese medicine suppository, to suppress the pathogenic bacterium of vagina; But in suppression or while killing vaginal pathogenic, also will affect the lactobacillus of vagina, the Tiny ecosystem of interference vagina, result causes vagina Effects on local immunological functions to decline, and vaginitis is easy to recurrence or protracted course of disease; And abnormal leucorrhea can not be reduced very soon, eliminate the red and swollen pruritus of pudendum that abnormal volume leucorrhea brings.Vaginitis severe patient even have impact on normal work and life, improves the sickness rate of gynecological tumor disease, and traditional antibiotics antibacterial, very strong drug resistance can be produced after long-time use, thus cause gynaecopathia recurrent exerbation, obstinate.
Summary of the invention
The object of the invention is for the deficiencies in the prior art, a kind of active carbon suppository for the treatment of cervical erosion and preparation method thereof is provided, this medicine is that one can anti-bacteria rapidly, safely in use simultaneously, effectively, have no side effect and not easily produce drug resistance, the more acceptant product of patient, has and all can cure and the feature of instant effect cervical erosion I, II, III degree.
The active carbon suppository that the present invention treats cervical erosion is made up of NACF ACF, carbomer, sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose, mixed fatty glycerides, gelatin, glycerol, purified water.It is fast that active carbon in the active carbon suppository for the treatment of cervical erosion has adsorption rate, absorption affinity is strong, the feature that adsorbance is large, at the thickening power of carbomer, the bonding of sodium carboxymethyl cellulose and filming function, under the figuration effect of mixing-in fat acid glycerol, formed with the ratio of clinical required NACF bore dia, by various malignant bacteria, viruses adsorption is in fiber holes, change its living environment, make it dead, thus reach antiinflammatory, pain relieving, hemostasis, deodorization, sterilizing, Promote cell's growth accelerates tissue regeneration, the effect of cure diseases, and antibacterial can not be made to produce drug resistance.Therapeutic Method is simple, determined curative effect, and patient compliance is good, in clinical extensive application.
In the present invention, medicine pharmacologically active used is as follows:
Active carbon is based on the material containing charcoal, there is good characterization of adsorption, its appearance luster is black, it contains a large amount of fiber holes, there is huge specific surface area, can effectively remove colourity, stink, most organic pollutants and some inorganic matter in secondary effluent can be removed, comprise the heavy metal that some is poisonous.
Carbomer, under very low consumption, (conventional amount used 0.25-0.5%) just can produce efficient thickening power, thus prepare that the emulsion of very wide range of viscosities and various flows degeneration, cream are white, gel and preparation capable of permeating skin.
Sodium carboxymethyl cellulose is used as pharmaceutical carrier in medical industry, as binding agent and the film former of suppository.
Mixed fatty glycerides is excipient.As suppository base, be a kind of carrier of suppository, that is adjuvant is that one is had many uses, the non-ionic surface active agent that output is larger.
Glycerol, be a kind of colourless or micro-yellow transparent thick liquid, nontoxic, odorless, non-corrosiveness, have stronger hygroscopicity, can generate multiple esters, can form polyglycerol under certain condition with mineral acid and organic acid reaction.
Gelatin is the mixtures of polypeptides of a kind of hot water soluble, and gelatin is medically being usually used in plasma expander and hemorrhage.
Activated carbon adsorption bolt of the present invention is well-designed according to female pathology structure, adopt built-in suppository type, be placed in the product that intravaginal is used for the treatment of colpitis, be mainly used in the inflammation such as treatment VVC, nonspecific vaginitis, bacterial vaginosis.
The invention has the beneficial effects as follows: the activated carbon adsorption bolt for the treatment of cervical erosion has the effect of antibacterial, antiinflammatory, hemostasis, removing abnormal flavour, do not destroy the normal environment of vagina, do not affect the growth of lactobacillus, have no drug resistance, antibacterial stable, has a broad antifungal spectrum, compliance that is easy to use, comfortable, pollution-free, patient is good.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is further described, but protection scope of the present invention be not limited thereto, every do not deviate from the present invention design change or equivalent replacement be all included in protection scope of the present invention.
The activated carbon adsorption bolt for the treatment of cervical erosion is made up of bolt grain and the medical absorbent cotton/gauze be wrapped in outside bolt grain.Bolt grain is made up of pharmaceutical grade activated carbon fiber ACF, carbomer, sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose, mixed fatty glycerides, gelatin, glycerol, purified water, for in vaginitis and other gynecological inflammations, mainly utilize the adsorptivity of activated carbon to reduce the concentration of antibacterial, reach therapeutic effect.
Formula and the consumption of active carbon suppository of the present invention are as follows:
The manufacturing process of active carbon suppository of the present invention is: the carbomer getting recipe quantity, and water intaking 100g, adds nanometer silver solution, carbomer is added in continuous stirring, mix homogeneously, adds and hankers adding mixed fatty glycerides, then adds triethylamine adjusting viscosity, sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose are mixed homogeneously with active carbon, add above-mentioned mixed solution, stir into dough, mould is injected in pressurization, freezing maintenance shape, takes out.Heat 4 hours at 80 DEG C, then 115 DEG C of heating 1 hour.Finally wrap up gauze, the two aluminum composite membrane bag sealing of dress, ethane via epoxyethane sterilization, mounted box.
Claims (4)
1. active carbon suppository for the treatment of cervical erosion and preparation method thereof, is characterized in that, this suppository is made up of bolt grain and the medical absorbent cotton/gauze be wrapped in outside bolt grain; Bolt grain is made up of pharmaceutical grade activated carbon fiber ACF, carbomer, sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose, mixed fatty glycerides, gelatin, glycerol, purified water, is used for the treatment of vaginitis and other gynecological inflammations.
2. a kind of active carbon suppository for the treatment of cervical erosion according to claim 1 and preparation method thereof, it is characterized in that, containing active carbon in bolt grain, having a large amount of fiber holes, huge specific surface area, adsorbable various malignant bacteria, virus, absorption affinity is strong, adsorbance is large.
3. a kind of active carbon suppository for the treatment of cervical erosion according to claim 1 and preparation method thereof, is characterized in that, bolt grain formula of the present invention and consumption as shown in the table:
4. a kind of active carbon suppository for the treatment of cervical erosion according to claim 1 and preparation method thereof, it is characterized in that, manufacturing process of the present invention is: get the carbomer of recipe quantity, water, nanometer silver solution, continuous stirring also adds carbomer, mix homogeneously, mixed fatty glycerides is added after heating, add triethylamine adjusting viscosity again, sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose are mixed homogeneously with active carbon, add above-mentioned mixed solution, stir into dough, mould is injected in pressurization, freezing maintenance shape, takes out; Heat 4 hours at 80 DEG C, then 115 DEG C of heating 1 hour; Finally wrap up gauze, the two aluminum composite membrane bag sealing of dress, ethane via epoxyethane sterilization, mounted box.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510196839.1A CN104840485A (en) | 2015-04-23 | 2015-04-23 | Active carbon suppository for treating cervical erosion, and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510196839.1A CN104840485A (en) | 2015-04-23 | 2015-04-23 | Active carbon suppository for treating cervical erosion, and preparation method thereof |
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| CN104840485A true CN104840485A (en) | 2015-08-19 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510196839.1A Pending CN104840485A (en) | 2015-04-23 | 2015-04-23 | Active carbon suppository for treating cervical erosion, and preparation method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105342983A (en) * | 2015-12-18 | 2016-02-24 | 安徽省微赢生物科技有限公司 | Activated carbon adsorption suppository and preparation method thereof |
| CN105362292A (en) * | 2015-12-18 | 2016-03-02 | 安徽省微赢生物科技有限公司 | Medicine composition for treating cervical erosion |
| CN105434334A (en) * | 2015-12-18 | 2016-03-30 | 上海韬鸿化工科技有限公司 | Active carbon suppository used for treating cervical erosion, and preparation method thereof |
| CN105497064A (en) * | 2015-12-18 | 2016-04-20 | 安徽省微赢生物科技有限公司 | Activated carbon suppository for treating cervical erosion and preparation method of activated carbon suppository |
| CN105520957A (en) * | 2015-12-18 | 2016-04-27 | 上海韬鸿化工科技有限公司 | Medicine composition for treating cervical erosion |
| CN105560163A (en) * | 2015-12-18 | 2016-05-11 | 上海韬鸿化工科技有限公司 | Activated carbon adsorption plug and preparation method thereof |
| CN105727428A (en) * | 2016-04-13 | 2016-07-06 | 邓育德 | Gauze coated tablet for treating gynecological inflammation and preparation method of gauze coated tablet |
-
2015
- 2015-04-23 CN CN201510196839.1A patent/CN104840485A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105342983A (en) * | 2015-12-18 | 2016-02-24 | 安徽省微赢生物科技有限公司 | Activated carbon adsorption suppository and preparation method thereof |
| CN105362292A (en) * | 2015-12-18 | 2016-03-02 | 安徽省微赢生物科技有限公司 | Medicine composition for treating cervical erosion |
| CN105434334A (en) * | 2015-12-18 | 2016-03-30 | 上海韬鸿化工科技有限公司 | Active carbon suppository used for treating cervical erosion, and preparation method thereof |
| CN105497064A (en) * | 2015-12-18 | 2016-04-20 | 安徽省微赢生物科技有限公司 | Activated carbon suppository for treating cervical erosion and preparation method of activated carbon suppository |
| CN105520957A (en) * | 2015-12-18 | 2016-04-27 | 上海韬鸿化工科技有限公司 | Medicine composition for treating cervical erosion |
| CN105560163A (en) * | 2015-12-18 | 2016-05-11 | 上海韬鸿化工科技有限公司 | Activated carbon adsorption plug and preparation method thereof |
| CN105520957B (en) * | 2015-12-18 | 2018-08-03 | 上海韬鸿化工科技有限公司 | A kind of pharmaceutical composition for treating cervical erosion |
| CN105727428A (en) * | 2016-04-13 | 2016-07-06 | 邓育德 | Gauze coated tablet for treating gynecological inflammation and preparation method of gauze coated tablet |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150819 |
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| WD01 | Invention patent application deemed withdrawn after publication |