CN104825944B - A kind of medicine for treating blood-head psoriasis pustulosa - Google Patents
A kind of medicine for treating blood-head psoriasis pustulosa Download PDFInfo
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Abstract
The invention discloses a kind of medicine for being used to treat blood-head psoriasis pustulosa, its bulk drug composition is：20 30 grams of radix rehmanniae recen, 20 30 grams of gypsum, 10 15 grams of Asian puccoon, 69 grams of radix glycyrrhizae, 10 15 grams of the radix paeoniae rubrathe, 69 grams of the wind-weed, windproof 69 grams, 10 15 grams of the root bark of shaggy-fruited dittany, 10 15 grams of the red sage root, 69 grams of zaocys dhumnade, 10 15 grams of folium isatidis, 10 15 grams of Radix Isatidis, 69 grams of moutan bark, 69 grams of Rhizoma Sparganii, 10 15 grams of radix scrophulariae, 10 grams of smilax, 12 grams of the root of bidentate achyranthes, 15 grams of honeysuckle, 15 grams of the capsule of weeping forsythia.Present invention has the advantages that treatment blood-head psoriasis pustulosa, quick, cure rate is high, and Small side effects, recurrence rate is low, and has no adverse reaction.It is currently a kind of newtype drug for treating blood-head psoriasis pustulosa.
Description
Technical field
The present invention relates to a kind of Chinese medicine compound prescription, more particularly to a kind of medicine for treating blood-head psoriasis pustulosa.
Background technology
Psoriasis is called psoriasis, and the traditional Chinese medical science is referred to as " white arrange ", refers to occur the drying of multilayer silvery white in erythema repeatedly
The chronic recurrent inflammatory dermatoses of the scales of skin that peel off, ancient medicine writings also have referred to as psoriasis, snake lice, white shell sore.Blood-head psoriasis pustulosa
Clinically to quickly grow, fash is scarlet, layer by layer the scales of skin that peel off, acute pruritus, and the scales of skin that peel off is stripped off, sieve-like blutpunkte is classical symptom.Disease
Journey is grown, easily recurrence.This disease is a kind of disease of multifactorial inheritance, and immune-mediated is its main mechanism, and risk factor is complicated more
Sample, it is relevant with bacteriovirus infection, inherent cause, stress and immunologic function disorder.This sick incidence of disease is higher, is easy to multiple
Hair, the course of disease is longer, is more especially to invade person between twenty and fifty, the health and spirit harm to patient are very big.This disease of western medical treatment with
Based on antineoplastic, corticosteroid, vitamin A acid, immunodepressant etc., side effect is big, and easily forms drug resistance and dependence
Property.Facts have proved psoriasis is the advantage disease of the traditional Chinese medical science, and diagnosis and treatment obtains preferable therapeutic effect.We pass through more than two decades
Continuous exploration, dialectical this disease for the treatment of have accumulated abundant clinical experience, and present invention treatment blood-head psoriasis pustulosa has cure rate
Height, Small side effects, advantage uneasy to recur, and drug resistance is not produced, it is the important development direction for treating psoriasis now.
The content of the invention
Present invention solves the technical problem that it is to provide a kind of medicine for treating blood-head psoriasis pustulosa.The drug therapy blood-heat type
Psoriasis is not only quick, and cure rate is high, and Small side effects, recurrence rate is low, has no adverse reaction；But also do not produce drug resistance.
The technical scheme is that:A kind of medicine for treating blood-head psoriasis pustulosa, it is characterized in that, its bulk drug composition
For：It is 20-30 grams of radix rehmanniae recen, 20-30 grams of gypsum, 10-15 grams of Asian puccoon, 6-9 grams of radix glycyrrhizae, 10-15 grams of the radix paeoniae rubrathe, 6-9 grams of the wind-weed, anti-
It is 6-9 grams of wind, 10-15 grams of the root bark of shaggy-fruited dittany, 10-15 grams of the red sage root, 6-9 grams of zaocys dhumnade, 10-15 grams of folium isatidis, 10-15 grams of Radix Isatidis, male
6-9 grams of the root bark of tree peony, 6-9 grams of Rhizoma Sparganii, 10-15 grams of radix scrophulariae, 10 grams of smilax, 12 grams of the root of bidentate achyranthes, 15 grams of honeysuckle, 15 grams of the capsule of weeping forsythia；
The medicine of the treatment blood-head psoriasis pustulosa is made as decoction；
The decoction decoction of medicine of the treatment blood-head psoriasis pustulosa is：Decoct first with 800-1000 milliliters of cold water, will be upper
State the radix rehmanniae recen prepared, Asian puccoon, radix glycyrrhizae, the radix paeoniae rubrathe, the wind-weed, the windproof, root bark of shaggy-fruited dittany, the red sage root, zaocys dhumnade, folium isatidis, Radix Isatidis, tree peony
Skin, Rhizoma Sparganii, radix scrophulariae, smilax, the root of bidentate achyranthes, honeysuckle, the capsule of weeping forsythia soak 30 points to 60 minutes；Simultaneously with 100-150 milliliters of cold water,
The above-mentioned gypsum prepared is soaked 30 points to 60 minutes；Gypsum is decocted first after 10-15 minutes with remaining medicine with decocting, and is cooked by slow fire
30 minutes, filter out concoction；Two decoct addition cold water or boiling water 500-800 milliliters, and slow fire decocts 20-25 minutes, filters out concoction twice again
Mix even.
Instructions of taking：The Chinese herbs decoction mixed will be decocted, the morning and evening point, 2 warms were for oral administration, medicine-feeding one, treatment in ten days one on the one
Journey, take 2 courses for the treatment of.Added and subtracted according to the state of an illness with card.Diet avoids pungent stimulation during medication, and taboo excites sex therapy, avoids scratching
And hot water is scalded；Control the emotion as far as possible, ensure sufficient sleep.
First, the effect of each material medicine and mechanism
Forward position means of the invention by using modern scientific research, studied so that differential diagnosis in tcm is theoretical with reference to herbal pharmacology,
Both the dialectical system of principle-method-recipe-medicines of the traditional Chinese medical science had strictly been deferred to, had been emphasized again based on the etiology and pathology of doctor trained in Western medicine, with reference to Chinese medicine validation
Study point, according to herbal pharmacology, drug effect and pharmacokinetics basis further investigated Chinese traditional treatment rule.Inventor thinks:Blood-head
The main reason for being the morbidity of this disease, inernal injuries caused by seven emotions, internal heat is interior to contain, incoordination between the spleen and the stomach, functional activity of QI being not smooth, strongly fragrant longization heat.Affection of exogenous wind-heat it
Evil visitor and skin, then skin breakouts, the bits scratched rise failure of skin and muscle to be nourished.The morbidity of psoriasis and heredity, infection, the obstacle of metabolism, exempt from
Epidemic disease dysfunction, dysendocrinism etc. are relevant, and it is special that silver bits skin lesion forms the pathology that epidermis paraplasm and scytitis coexist
Sign.Therefore the present invention establishes clearing heat and cooling blood, clearing heat and detoxicating, clearing heat-fire primary treatments, takes into account other pathological factors.This
Inventing the Chinese medicine selected being capable of clearing heat and cooling blood, removing toxic substances purging intense heat；Dispelling wind and arresting itching；It is promoting blood circulation and removing blood stasis；Build up health, adjust immunity.
Radix rehmanniae recen：It is sweet, bitter, cold.The thoughts of returning home, liver and kidney channel.Effect：Clearing heat and cooling blood, nourishing Yin and promoting production of body fluid, ease constipation.
Gypsum：Pungent, sweet, Great Cold.Attach to the lung and stomach meridians.Effect：Clearing heat-fire, relieving restlessness are quenched the thirst.
Asian puccoon：It is sweet, cold.Effect：Cooling and activating blood, promoting eruption of detoxifying.
Radix glycyrrhizae：It is sweet, flat.The thoughts of returning home, lung, spleen, stomach.Effect：
The radix paeoniae rubrathe：Hardship, it is slightly cold.Return liver warp.Effect：Clearing heat and cooling blood, stasis-dispelling and pain-killing.
The wind-weed：It is bitter, sweet, cold.Return lung, stomach, kidney channel.Effect：Clearing heat-fire, nourishing Yin and moistening dryness.
It is windproof：Pungent, sweet, tepor.Return bladder, liver, the spleen channel.Effect：Expel pathogenic wind from the body surface, victory is wet, analgesic, spasmolysis.
The root bark of shaggy-fruited dittany：It is bitter, cold.Effect：It is clearing heat and detoxicating, dispel pathogenic wind and remove dampness, it is antipruritic.
The red sage root：Hardship, it is slightly cold.The thoughts of returning home, pericardium, Liver Channel.Effect：Invigorate blood circulation, stasis-dispelling and pain-killing, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle.
Zaocys dhumnade：It is sweet, flat.Effect：Wind dispelling dredging collateral, arresting convulsion stop convulsion.
Folium isatidis：Bitter, Great Cold.The thoughts of returning home, lung, stomach.Effect：It is clearing heat and detoxicating, blood cooling and ecchymoses removing, reducing pharyngeal swelling.
Radix Isatidis：It is bitter, cold.The thoughts of returning home, stomach.Effect：It is clearing heat and detoxicating, cool blood, relieving sore-throat.
Moutan bark：It is bitter, pungent, be slightly cold.The thoughts of returning home, liver and kidney channel.Effect：Clearing heat and cooling blood, promoting blood circulation to remove blood stasis.
Rhizoma Sparganii：It is bitter, flat.Effect：Dissipating blood stasis with potent drugs, promoting qi circulation and relieving pain.
Radix scrophulariae：It is bitter, sweet, salty, cold.Return lung, stomach, kidney channel.Effect：Clearing heat and cooling blood, nourishing Yin and falling fire, detoxicating and resolving a mass, ease constipation.
Smilax：It is sweet, light, flat.Effect：Removing toxic substances, dehumidifying, sharp joint.
The root of bidentate achyranthes：It is bitter, sour, flat.Return liver and kidney channel.Effect：Dispelling stasis of blood and stimulating the menstrual flow, filling liver kidney, strengthening the bones and muscles, ensuring proper downward flow of the blood, diuresis is led to
Leaching.
Honeysuckle:It is sweet, cold.Return lung, stomach, large intestine channel.Effect：It is clearing heat and detoxicating, dispelling wind and heat from the body.
The capsule of weeping forsythia：Hardship, it is slightly cold.Return lung, the heart, gallbladder channel.Effect：It is clearing heat and detoxicating, dispelling wind and heat from the body, carbuncle that disappears dissipating bind, diuresis.
As described above, the principle pathological mechanism of blood-head psoriasis pustulosa is accumulate in blood-head, dryness-transformation life wind, failure of skin and muscle to be nourished forms.
Above-mentioned radix rehmanniae recen clearing heat and cooling blood selected by the present invention, nourishing Yin and promoting production of body fluid, kidney tonifying water is Kidney-Yin；Radix scrophulariae clearing heat and cooling blood enriching yin, kidney tonifying gas, solve spot
Poison, it is altogether monarch drug in a prescription with the mutual reinforcement between of radix rehmanniae recen clearing heat and cooling blood ecchymose removing to use.Gypsum clearing heat-fire, convergence myogenic, solve skin heat；Know
Female clearing heat-fire, nourishing Yin and moistening dryness, the two mutual reinforcement between strengthen the effect of clearing heat and cooling blood to use.Folium isatidis is clearing heat and detoxicating, blood cooling and ecchymoses removing, controls
Wind-heat macula；Radix Isatidis is clearing heat and detoxicating, cool blood, can solve all malicious malignant sores.Moutan bark, radix paeoniae rubrathe clearing heat and cooling blood dissipate the stasis of blood, it in energy promoting circulation of blood
It is stagnant；Asian puccoon removing pattogenic heat from the blood and toxic material from the body promoting eruption, controls macula；Above-mentioned all medicines share, clearing heat and cooling blood, stagnation resolvation spot is dissipated, is altogether ministerial drug, closed with monarch drug in a prescription
With further enhancing the work(of the clearing heat and cooling blood ecchymose removing of monarch drug in a prescription, and row is clearing heat and detoxicating, dissipates the effect of stagnation resolvation spot.It is windproof to deliver scattered wind,
It is antipruritic, dissipate fleshy exterior ailment said due to cold or exposure；Zaocys dhumnade dispelling wind and removing obstruction in the meridians, main all urticarias, munbness；Root bark of shaggy-fruited dittany heat-clearing dispelling wind and arresting itching；Three closes
With treatment and disease pruritus.The red sage root is promoting blood circulation and removing blood stasis, and cool blood to disappear carbuncle, myogenic is put on flesh；Rhizoma Sparganii blood-breaking disperse accumulations, it is hard to control caking sore, hard
What person cut；Papillary is promoting blood circulation and removing blood stasis, the power of dissipating bind ecchymose removing more very.Above-mentioned all medicines are directed to and disease antipruritic, the dissolving stasis that plays scattered wind
The work(of ecchymose removing, it is altogether adjutant.Help above-mentioned ministerial drug to further enhance clearing heat and cooling blood altogether, dissipate the effect of stagnation resolvation spot.Radix glycyrrhizae is clearing heat and detoxicating, energy
Coordinating the drug actions of a prescription, the strong of medicine is relaxed, mitigate toxic side effect, to make medicine.
Honeysuckle, the capsule of weeping forsythia are added in the present invention, because of equal thoughts of returning home lung, function is clearing heat and detoxicating, dispelling wind and heat from the body, to fever caused by exogenous pathogenic factors,
No matter it is evil defend, gas, or battalion, blood is suitable, helps that radix rehmanniae recen, radix scrophulariae row are clearing heat and detoxicating, dissipate the effect of stagnation resolvation spot altogether.Smilax profit
Wet removing toxic substances can sharp joint, root of bidentate achyranthes Stasis through, strengthening the bones and muscles, the work of the present invention can be strengthened by adding two medicines and the red sage root, Rhizoma Sparganii compatibility
The work(of blood and dissolving stasis, dredging collateral.
All medicines share, can clearing heat and cooling blood；Dispelling wind and arresting itching；Eliminating blood stasis and removing ecchymoses；Nourishing Yin and moistening dryness；So as to treat both principal and secondary aspect of disease, actual situation is simultaneously adjusted.
This disease is treated, enables the heat removing summer-heat in blood, the malicious stasis of blood in blood is able to row and dissipated, and dispels ailment said due to cold or exposure, blood cooling and ecchymoses removing, hot clear spot is disappeared and itch
Only.The present invention controls for etiological analysis and differentiation opinion, consolidates and radically reforms, it is uneasy to recur to consolidate disease.
2nd, the medicine modern pharmacology pharmacodynamic action of above-mentioned treatment blood-head psoriasis pustulosa shows in the following areas：
Antipyretic, analgesia：Gypsum, the wind-weed, radix rehmanniae recen, radix scrophulariae, moutan bark, folium isatidis, the radix paeoniae rubrathe, the black tip in the present invention
Snake, Rhizoma Sparganii etc. have a clearing heat and cooling blood respectively, heat in releasing, remove endotoxin, analgesic effect.
Antibacterial, anti-inflammatory：The present invention is from radix rehmanniae recen, the wind-weed, moutan bark, folium isatidis, Radix Isatidis, the root bark of shaggy-fruited dittany, radix glycyrrhizae, gold and silver
The medicines such as flower, there is obvious antibacterial, antivirus action, to the infection of the upper respiratory tract, tonsillitis, parotitis, spore exanthema virus, disease
Pathogenic microorganism has obvious therapeutic action, thus has obvious antiinflammatory action.
Enhancing is immune, antiallergic action, antiallergy：The present invention from gypsum, radix rehmanniae recen, windproof, moutan bark, Asian puccoon,
Radix scrophulariae, folium isatidis, Radix Isatidis, red sage root etc. can strengthen the immunity of body, have body and protect itself from other materials
The characteristic of infringement.In psoriatic lesion, epidermis and intradermal are with the presence of the excessive T cell activated.Asian puccoon is also to granulation group
The propagation knitted has facilitation, hence it is evident that accelerates the healing of wound, a small amount of use can slow down the keratinization of skin.
Cortex hormone of aadrenaline acts on：Radix glycyrrhizae in the present invention has adrenocortical hormones fuction, and radix rehmanniae recen can be prevented
Only Adrenal cortex atrophy, promote the synthesis of cortex hormone of aadrenaline.
Improve microcirculation：Silver bits skin lesion forms the pathological characters of epidermis paraplasm, according to pharmacological research and largely faces
Bed practice have shown that, activating blood and removing stasis drug-red sage root, Rhizoma Sparganii in the present invention can improve hemorheological property, improve microcirculation, remove
Ecchymosis at skin lesion, so as to promote the reparation of skin injury.
3rd, observation of curative effect method of the present invention
1.1st, research process of the present invention, all from Dermatology Outpatient Department outpatients, blood-head psoriasis pustulosa is diagnosed as, is examined
Disconnected standard according to《Surgery of Chinese Medicine》.Clinical manifestation continuously emerges for fash, quickly grows, some drop-wise are presented more, and color is scarlet,
The scales of skin that peel off increases, acute pruritus, and that grabs has sieve-like blutpunkte；With mouth parched and tongue scorched, have sore throat, dysphoria, be hard and dry, urine
Huang Chi；Red tongue body moss thin yellow, wiry and rolling pulse or number, 56 are screened altogether.Exclusion standard：Serious cardiovascular, liver kidney and endocrine etc. are
System disease；Inscribed systematic treating received and included the patient of hormone, immunodepressant and retinoid medicine within 4 weeks before treatment；Its
His class psoriasis pustulosa；Pregnant and lactant women.It is randomly divided into two groups.Treatment group 28, man 12, female 16；Age 19~
It is 58 years old, average 32.5 years old；The course of disease 7~30 days, it is average 14 days.Control group 28, man 15, female 13；At 21~54 years old age, put down
Equal 29.5 years old；The course of disease 7~30 days, it is average 20 days.Not statistically significant (the P of comparing difference such as two groups of ages, sex, the course of disease, state of an illness
>0.05), there is comparativity.
1.2nd, treatment method：Sooner or later point 2 warms take decoction of the present invention orally for treatment group, and one one；Control group：Use Xiaoyin
Capsule Chinese medicines quasi-word Z200001 10；Shaanxi Mo Mei get pharmaceutical Co. Ltds produce) 5~7,3 times a day.Two groups are treated 2
The course for the treatment of, ten days courses for the treatment of.Withdraw other drugs during medication, avoid eating the product of the pungent fatness, sweet, thick and oily of seafood.
1.3rd, criterion of therapeutical effect：Commented according to international psoriatic lesion area severity index (PASI) standards of grading
Valency curative effect.Recovery from illness：PASI integrations decline >=90%, and skin lesion is all disappeared or only remains a small number of drop infringements, and itch disappears；It is aobvious
Effect：Decline 60%~89%, skin lesion regression more than 60%, occasionally there is itch；Effectively：Decline 25% one 59%, skin lesion disappears 30%
More than, still there is itch；It is invalid：Integration declines<25%, skin lesion disappears less than 30% or without improvement, hence it is evident that itch, it is difficult to endure.
Recovery from illness, effective, effectively total calculating is efficient.Follow-up observation is carried out to recovery from illness patient and effective patient, as PASI is accumulated after 6 months
Rising 50% when relatively stopping treatment being divided to be judged to recur.
2.1 treatment results are as follows：
The pretherapy and post-treatment PASI scorings of 1 two groups of patients of table are compared
2 two groups of patient outcomes of table compare
| Group | Recovery from illness | It is effective | Effectively | It is invalid | Efficient % |
| Treatment group | 8 | 14 | 3 | 3 | 89.3 |
| Control group | 2 | 7 | 9 | 10 | 64.3 |
Two groups of data compare to be examined using x2, P<0.05 is that difference is statistically significant.
Follow-up half a year recurrence after 3 two groups of patient's treatments of table
2.2nd, adverse reaction and safety detection：Treatment group has 2 loose stools occur, and 4 slight upper abdomens occurs in control group
Discomfort, do not influence further to treat, pretherapy and post-treatment blood, routine urinalysis, the detection of hepatic and renal function are showed no obvious abnormalities.
It can be seen that from the data of above table and take traditional Chinese herbal decoction treatment blood-head psoriasis pustulosa provided by the invention, have
Xiao Shuai ﹙ recoveries from illness plus effective it is substantially better than control group added with Xiao ﹚；Two groups of adverse reaction rates and performance no significant difference；Fully recover, be effective
Patient's half a year recurrence rate is significantly lower than control group.
4th, medical record is illustrated；
1, patient Jiang, man, 56 years old, in more than 30 years of history of psoriasis, once repeated multiple times treatment, easily recurred after healing, recently
For seance before 13 months, patient's addiction is pungent.Patient plays red skin immediately without obvious inducement whole skin itch before first quarter moon
Rash, there is the white scales of skin that peel off, do not treat outside, to examine.Have a medical check-up：The general rubescent color spot papule of entire patient, soybean grain are big to flap
Small, the thin white scales of skin that peel off of overlying, Ovshinsky sign is positive, has isomorphic response, pencil hair, scratch is obvious, there is scab.Red tongue body, moss thin yellow, arteries and veins
String is slided.Patient's private prosecution gargalesthesia weight, mood is irritable, dysphoria.PASI scorings 15.47, blood urine routine and hepatic and renal function check nothing
It is abnormal.Prescription：It is 20 grams of radix rehmanniae recen, 30 grams of gypsum, 12 grams of Asian puccoon, 6 grams of radix glycyrrhizae, 10 grams of the radix paeoniae rubrathe, 9 grams of the wind-weed, windproof 6 grams, white
15 grams of fresh hide, 15 grams of the red sage root, 6 grams of zaocys dhumnade, 10 grams of folium isatidis, 15 grams of Radix Isatidis, 6 grams of moutan bark, 9 grams of Rhizoma Sparganii, 12 grams of radix scrophulariae,
10 grams of smilax, 15 grams of the capsule of weeping forsythia.Decoct first with 800-1000 milliliters of cold water by the radix rehmanniae recen prepared, Asian puccoon, radix glycyrrhizae, the radix paeoniae rubrathe,
The wind-weed, the windproof, root bark of shaggy-fruited dittany, the red sage root, zaocys dhumnade, folium isatidis, Radix Isatidis, moutan bark, Rhizoma Sparganii, radix scrophulariae, smilax, capsule of weeping forsythia immersion 30
Divide to 60 minutes；The gypsum prepared is soaked 30 points to 60 minutes with 100-150 milliliters of cold water simultaneously；Gypsum is decocted first
It is cooked by slow fire 30 minutes with decocting with remaining medicine after 10-15 minutes, filters out concoction；Two decoct addition cold water or boiling water 500-800 millis
Rise, slow fire again decoct 20-25 minutes, filter out twice concoction mix it is even.The Chinese herbs decoction mixed will be decocted, point 2 warms are for oral administration sooner or later.
One one, and 10 are a course for the treatment of, and after taking two courses for the treatment of, entire patient's fash disappears substantially, and only both legs is dispersed at 5 and omited
Point drop-wise higher than surface is damaged, and no scales of skin that peel off, gargalesthesia disappears, and affected part is left crineous color and sunk.PASI scorings 1.92, check blood urine
Routine and liver function kidney function are without exception.Follow-up half a year is without recurrence.
2, patient pays so-and-so, and man, whole body plays red rash after being caught a cold before 36 years old, 6 days, and color is red, itch, does not control outside
Treat, to examine.Have a medical check-up：Entire patient distributes red point drop-wise fash, needle point to soybean grain size, the thin white scales of skin that peel off of overlying, Ovshinsky sign
The positive, based on trunk, there is scratching trace.Congestion of throat, swelling and pain.PASI scorings 14.93, blood routine：Leucocyte 9600, it is neutral
Leucocyte 72%, routine urinalysis and hepatic and renal function are without exception.Prescription：25 grams of radix rehmanniae recen, 25 grams of gypsum, 10 grams of Asian puccoon, radix glycyrrhizae 9
Gram, 12 grams of the radix paeoniae rubrathe, 6 grams of the wind-weed, windproof 9 grams, 12 grams of the root bark of shaggy-fruited dittany, 12 grams of the red sage root, 9 grams of zaocys dhumnade, 12 grams of folium isatidis, Radix Isatidis 10
Gram, 6 grams of moutan bark, 6 grams of Rhizoma Sparganii, 15 grams of radix scrophulariae.Decoct first with 800-1000 milliliters of cold water by the radix rehmanniae recen prepared, Asian puccoon,
Radix glycyrrhizae, the radix paeoniae rubrathe, the wind-weed, the windproof, root bark of shaggy-fruited dittany, the red sage root, zaocys dhumnade, folium isatidis, Radix Isatidis, moutan bark, Rhizoma Sparganii, radix scrophulariae soak 30 points
To 60 minutes；The gypsum prepared is soaked 30 points to 60 minutes with 100-150 milliliters of cold water simultaneously；Gypsum is decocted first 10-
It is cooked by slow fire 30 minutes with decocting with remaining medicine after 15 minutes, filters out concoction；Two decoct addition cold water or boiling water 500-800 milliliters, text
Fire again decoct 20-25 minutes, filter out twice concoction mix it is even.The Chinese herbs decoction mixed will be decocted, point 2 warms are for oral administration sooner or later.One day
One, 10 are a course for the treatment of, and after taking 10 days, patient's fash fading 95%, gargalesthesia is disappeared, and abscess of throat takes a turn for the better, and PASI is commented
Divide 1.85, check blood routine：Leucocyte 6400, neutrocyte 56%.Routine urinalysis and hepatic and renal function are without exception.Follow-up half a year without
Recurrence.
3, patient's fourth so-and-so, female, 19 years old, there is red rash without obvious inducement both legs before more than 20 days, there is white furfur,
Itch, there is sieve-like blutpunkte after scratching.His father has psoriasis medical history.Do not treat outside, to examine.Have a medical check-up：Patient's both legs dissipates
Rubescent color spot papule, the thin white scales of skin that peel off of overlying is positive in hat shape, scales of skin that peel off consolidation, Ovshinsky sign, scratch, there is scab.Blood urine routine and liver
Kidney function test is without exception.PASI comments 12.46.Prescription：30 grams of radix rehmanniae recen, 20 grams of gypsum, 15 grams of Asian puccoon, 6 grams of radix glycyrrhizae, the radix paeoniae rubrathe
15 grams, 6 grams of the wind-weed, windproof 9 grams, 10 grams of the root bark of shaggy-fruited dittany, 10 grams of the red sage root, 9 grams of zaocys dhumnade, 15 grams of folium isatidis, 12 grams of Radix Isatidis, tree peony
9 grams of skin, 9 grams of Rhizoma Sparganii, 10 grams of radix scrophulariae, 10 grams of smilax, 12 grams of the root of bidentate achyranthes, 15 grams of honeysuckle, 15 grams of the capsule of weeping forsythia.Decoct first with cold water
800-1000 milliliters by the radix rehmanniae recen prepared, Asian puccoon, radix glycyrrhizae, the radix paeoniae rubrathe, the wind-weed, the windproof, root bark of shaggy-fruited dittany, the red sage root, zaocys dhumnade, big
Leafiness, Radix Isatidis, moutan bark, Rhizoma Sparganii, radix scrophulariae, smilax, the root of bidentate achyranthes, honeysuckle, the capsule of weeping forsythia soak 30 points to 60 minutes；Simultaneously with cold
The gypsum prepared is soaked 30 points to 60 minutes by 100-150 milliliters of water；Gypsum is decocted first after 10-15 minutes and remaining medicine
Thing is cooked by slow fire 30 minutes with decocting, filters out concoction；Two decoct addition cold water or boiling water 500-800 milliliters, and slow fire decocts 20-25 minutes again,
Filter out twice concoction mix it is even.The Chinese herbs decoction mixed will be decocted, point 2 warms are for oral administration sooner or later.One one, and 10 are a treatment
Journey, after taking 2 courses for the treatment of, the basic fading of patient's fash, leave point drop-wise at 6 and damage, gargalesthesia disappears, PASI scorings 1.87, multiple
Have a blood test routine urinalysis and hepatic and renal function it is without exception, follow-up half a year is without recurrence.
Present invention has the advantages that：The pharmacology of the present invention is treatment blood-head psoriasis pustulosa, has quick, cure rate
Height, Small side effects, the advantages such as recurrence rate is low, and have no adverse reaction；It is of the invention can clearing heat and cooling blood, dispelling wind and arresting itching, eliminating blood stasis and removing ecchymoses,
Nourishing Yin and moistening dryness, enables the heat removing summer-heat in blood, and the malicious stasis of blood in blood is able to row and dissipated, and the clear spot of heat, which disappears, itches only；And drug resistance is not produced, mesh
Before be treat blood-head psoriasis pustulosa a kind of newtype drug.
Embodiment
The specific embodiment of the invention is：
Embodiment 1,
A, 20 grams of radix rehmanniae recen, 30 grams of gypsum, 12 grams of Asian puccoon, 6 grams of radix glycyrrhizae, 10 grams of the radix paeoniae rubrathe, 9 grams of the wind-weed, windproof 6 are weighed
Gram, 15 grams of the root bark of shaggy-fruited dittany, 15 grams of the red sage root, 6 grams of zaocys dhumnade, 10 grams of folium isatidis, 15 grams of Radix Isatidis, 6 grams of moutan bark, 9 grams of Rhizoma Sparganii, radix scrophulariae
12 grams, 10 grams of smilax, 15 grams of the capsule of weeping forsythia；
B, first decoct with 800-1000 milliliters of radix rehmanniae recens for having prepared step A of cold water, Asian puccoon, radix glycyrrhizae, the radix paeoniae rubrathe, the wind-weed,
The windproof, root bark of shaggy-fruited dittany, the red sage root, zaocys dhumnade, folium isatidis, Radix Isatidis, moutan bark, Rhizoma Sparganii, radix scrophulariae, smilax, the capsule of weeping forsythia soak 30 points extremely
60 minutes；Simultaneously 30 points to 60 minutes are soaked with 100-150 milliliters of gypsums for having prepared step A of cold water；Gypsum is decocted first
It is cooked by slow fire 30 minutes with decocting with remaining medicine after 10-15 minutes, filters out concoction；Two decoct addition cold water or boiling water 500-800 millis
Rise, slow fire again decoct 20-25 minutes, filter out twice concoction mix it is even.The Chinese herbs decoction mixed will be decocted, point 2 warms are for oral administration sooner or later.
One one.
Embodiment 2
A, 25 grams of radix rehmanniae recen, 25 grams of gypsum, 10 grams of Asian puccoon, 9 grams of radix glycyrrhizae, 12 grams of the radix paeoniae rubrathe, 6 grams of the wind-weed, windproof 9 are weighed
Gram, 12 grams of the root bark of shaggy-fruited dittany, 12 grams of the red sage root, 9 grams of zaocys dhumnade, 12 grams of folium isatidis, 10 grams of Radix Isatidis, 6 grams of moutan bark, 6 grams of Rhizoma Sparganii, radix scrophulariae
15 grams standby；
B, first decoct with 800-1000 milliliters of radix rehmanniae recens for having prepared step A of cold water, Asian puccoon, radix glycyrrhizae, the radix paeoniae rubrathe, the wind-weed,
The windproof, root bark of shaggy-fruited dittany, the red sage root, zaocys dhumnade, folium isatidis, Radix Isatidis, moutan bark, Rhizoma Sparganii, radix scrophulariae soak 30 points to 60 minutes；While with
The gypsum that 100-150 milliliters of cold water has prepared step A soaks 30 points to 60 minutes；Gypsum be decocted first after 10-15 minutes with
Remaining medicine is cooked by slow fire 30 minutes with decocting, filters out concoction；Two decoct addition cold water or boiling water 500-800 milliliters, and slow fire decocts 20- again
25 minutes, filter out twice concoction mix it is even.The Chinese herbs decoction mixed will be decocted, point 2 warms are for oral administration sooner or later.One one.
Embodiment 3
A, 30 grams of radix rehmanniae recen, 20 grams of gypsum, 15 grams of Asian puccoon, 6 grams of radix glycyrrhizae, 15 grams of the radix paeoniae rubrathe, 6 grams of the wind-weed, windproof 9 are weighed
Gram, 10 grams of the root bark of shaggy-fruited dittany, 10 grams of the red sage root, 9 grams of zaocys dhumnade, 15 grams of folium isatidis, 12 grams of Radix Isatidis, 9 grams of moutan bark, 9 grams of Rhizoma Sparganii, radix scrophulariae
10 grams, 10 grams of smilax, 12 grams of the root of bidentate achyranthes, 15 grams of honeysuckle, 15 grams of the capsule of weeping forsythia it is standby；
B, first decoct with 800-1000 milliliters of radix rehmanniae recens for having prepared step A of cold water, Asian puccoon, radix glycyrrhizae, the radix paeoniae rubrathe, the wind-weed,
The windproof, root bark of shaggy-fruited dittany, the red sage root, zaocys dhumnade, folium isatidis, Radix Isatidis, moutan bark, Rhizoma Sparganii, radix scrophulariae, smilax, the root of bidentate achyranthes, honeysuckle, company
Stick up 30 points to 60 minutes of immersion；Simultaneously 30 points to 60 points are soaked with 100-150 milliliters of gypsums for having prepared step A of cold water
Clock；Gypsum is decocted first after 10-15 minutes with remaining medicine with decocting, and is cooked by slow fire 30 minutes, filters out concoction；Two decoct addition cold water or open
Water 500-800 milliliters, slow fire again decoct 20-25 minutes, filter out twice concoction mix it is even.The Chinese herbs decoction mixed will be decocted, divides 2 sooner or later
Secondary warm is for oral administration.One one.
Claims (1)
1. a kind of medicine for treating blood-head psoriasis pustulosa, it is characterized in that, its bulk drug composition is：20-30 grams of radix rehmanniae recen, gypsum
20-30 grams, 10-15 grams of Asian puccoon, 6-9 grams of radix glycyrrhizae, 10-15 grams of the radix paeoniae rubrathe, 6-9 grams of the wind-weed, windproof 6-9 grams, 10-15 grams of the root bark of shaggy-fruited dittany,
It is 10-15 grams of the red sage root, 6-9 grams of zaocys dhumnade, 10-15 grams of folium isatidis, 10-15 grams of Radix Isatidis, 6-9 grams of moutan bark, 6-9 grams of Rhizoma Sparganii, profound
10-15 grams of ginseng, 10 grams of smilax, 12 grams of the root of bidentate achyranthes, 15 grams of honeysuckle, 15 grams of the capsule of weeping forsythia；
The medicine of the treatment blood-head psoriasis pustulosa is made as decoction；
The decoction decoction of medicine of the treatment blood-head psoriasis pustulosa is：Decoct with 800-1000 milliliters of cold water, match somebody with somebody above-mentioned first
Good radix rehmanniae recen, Asian puccoon, radix glycyrrhizae, the radix paeoniae rubrathe, the wind-weed, the windproof, root bark of shaggy-fruited dittany, the red sage root, zaocys dhumnade, folium isatidis, Radix Isatidis, moutan bark,
Rhizoma Sparganii, radix scrophulariae, smilax, the root of bidentate achyranthes, honeysuckle, the capsule of weeping forsythia soak 30 points to 60 minutes；, will be upper simultaneously with 100-150 milliliters of cold water
State the gypsum prepared and soak 30 points to 60 minutes；Gypsum is decocted first after 10-15 minutes with remaining medicine with decocting, and is cooked by slow fire 30 points
Clock, filter out concoction；Two decoct and add cold water or boiling water 500-800 milliliters, and slow fire decocts 20-25 minutes again, filter out twice concoction mix it is even.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510204216.4A CN104825944B (en) | 2015-04-24 | 2015-04-24 | A kind of medicine for treating blood-head psoriasis pustulosa |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510204216.4A CN104825944B (en) | 2015-04-24 | 2015-04-24 | A kind of medicine for treating blood-head psoriasis pustulosa |
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| CN104825944B true CN104825944B (en) | 2018-03-06 |
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| CN105031012A (en) * | 2015-08-19 | 2015-11-11 | 胥丹 | Traditional Chinese medicine composition for treating psoriasis |
| CN108175838B (en) * | 2018-03-26 | 2021-03-16 | 王吉坤 | Fuming and washing medicine for treating blood-heat type psoriasis |
| CN108186863A (en) * | 2018-03-28 | 2018-06-22 | 商丘市康都皮肤病研究院 | A kind of Chinese medicine for treating psoriasis |
| CN114796139A (en) * | 2022-04-28 | 2022-07-29 | 阿克曼皮肤医院投资有限公司 | Traditional Chinese medicine pill for treating blood-heat psoriasis vulgaris |
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