CN104815303A - Medicine for treating habitual nosebleed and preparation method thereof - Google Patents
Medicine for treating habitual nosebleed and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a medicine for treating habitual nosebleed and a preparation method thereof. The medicine comprises the following ingredients in parts by mass: 4-13 parts of fructus gardeniae, 4-13 parts of lalang grass rhizome, 10-20 parts of rhizoma zingiberis, 5-14 parts of pollen typhae carbonisatus, 3-8 parts of radix rehmanniae, 3-9 parts of radix angelicae, 7-15 parts of radix trichosanthis, 6-13 parts of radix bupleuri, 2-8 parts of tuber fleeceflower stem, 2-8 parts of cortex lycii radicis, 1-6 parts of dragon's bone, 1-6 parts of jujube, 1-5 parts of lalang grass rhizome and 0.5-3 parts of furnace soil. The medicine can quickly cure habitual nosebleed, has the functions of clearing heat and promoting fluid, cooling blood, clearing deficient heat, replenishing blood and the like, has a certain nerve soothing function, and is helpful to improve the sleep quality of people.
Description
Technical field
The invention belongs to the field of Chinese medicines, particularly relate to and a kind ofly treat medicament of habitual epistaxis and preparation method thereof.
Background technology
Habitual epistaxis with
nasal septumfront lower place is the most common, and minority can from nasal cavity rear portion.The former checks that can see local has vasodilation, mucosal ulcer or petechia, and the latter local may without any discovery.Also can be due to systemic disease secondary hemorrhage person, there is no protopathy sings and symptoms.
In general, the citizen suffering from flu are also the phenomenons that there will be epistaxis, this is because flu can make the resistance of nasal mucosa reduce, add the symptom of flu, such as have a stuffy nose, runny nose, patient can be made the to make action that some directly hurt nasal mucosa such as nose pus, such as firmly blowing one's nose, dig nostril etc., is the phenomenon than being easier to occur epistaxis like this.Also have and suffer from because itchy, runny nose, nasal obstruction, often can pick the nose, thus make nasal mucosa often injured and bleed.Have habitual epistaxis will arrive hospital to treat.
There is the medicine of some treatment epistaxis in the market, also fine to the curative effect of epistaxis, but the radical cure time is slow, the effect generally also not having clearing away heat and promoting production of body fluid, removing heat from blood, clearind deficient heat and enrich blood.Such as Chinese invention patent (the patent No. 201410162414.4, the applying date 2014/04/22) disclose a kind of Chinese medicine composition for the treatment of epistaxis, the one-tenth primarily of following weight parts is grouped into: 6g, Semen Benincasae 9g under glue pearl 9g, Flos Carthami 9g, Fructus Corni 10g, Cortex Moutan 10g, Radix Rehmanniae 20g, Rhizoma Dioscoreae 15g, river, Radix Notoginseng 6g, Radix Ophiopogonis 15g, Natrii Sulfas 9g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g.Chinese medicine formula disclosed in this patent of invention for the repeatability of epistaxis, when chronicity is bled more than, can be controlled timely and effectively, prove through Long-term clinical experiment, Chinese medicine composition of the present invention hemostasis in four days, radical cure in seven days, no longer recur, and without any side effects.
Summary of the invention
the technical problem solved:the healing time existed for existing treatment epistaxis medicine is slow, the shortcoming of the effect such as not there is clearing away heat and promoting production of body fluid, removing heat from blood, clearind deficient heat and enrich blood, the invention provides and a kind ofly treat medicament of habitual epistaxis and preparation method thereof, this medicament can the habitual epistaxis of rapid healing, and there is clearing away heat and promoting production of body fluid, removing heat from blood, clearind deficient heat, the function such as to enrich blood.
technical scheme:treat a medicament for habitual epistaxis, in mass parts containing following composition:
Fructus Gardeniae 4 ~ 13 parts,
Rhizoma Imperatae 4 ~ 13 parts,
Rhizoma Zingiberis 10 ~ 20 parts,
Pollen Typhae carbon 5 ~ 14 parts,
3 ~ 8 parts, the Radix Rehmanniae,
The Radix Angelicae Dahuricae 3 ~ 9 parts,
Radix Trichosanthis 7 ~ 15 parts,
Radix Bupleuri 6 ~ 13 parts,
Caulis Polygoni Multiflori 2 ~ 8 parts,
Cortex Lycii 2 ~ 8 parts,
Os Draconis 1 ~ 6 part,
1 ~ 6 part, Fructus Jujubae,
Rhizoma Imperatae 1 ~ 5 part,
Humus flava usta 0.5 ~ 3 part.
A kind of medicament for the treatment of habitual epistaxis described above, in mass parts containing following composition:
Fructus Gardeniae 6 ~ 11 parts,
Rhizoma Imperatae 7 ~ 12 parts,
Rhizoma Zingiberis 12 ~ 18 parts,
Pollen Typhae carbon 6 ~ 11 parts,
4 ~ 7 parts, the Radix Rehmanniae,
The Radix Angelicae Dahuricae 4 ~ 8 parts,
Radix Trichosanthis 9 ~ 14 parts,
Radix Bupleuri 7 ~ 11 parts,
Caulis Polygoni Multiflori 3 ~ 7 parts,
Cortex Lycii 3 ~ 7 parts,
Os Draconis 2 ~ 5 parts,
2 ~ 5 parts, Fructus Jujubae,
Rhizoma Imperatae 2 ~ 4 parts,
Humus flava usta 1 ~ 2.8 part.
A kind of medicament for the treatment of habitual epistaxis described above, in mass parts containing following composition:
Fructus Gardeniae 8 ~ 10 parts,
Rhizoma Imperatae 9 ~ 11 parts,
Rhizoma Zingiberis 14 ~ 16 parts,
Pollen Typhae carbon 8 ~ 10 parts,
5 ~ 6 parts, the Radix Rehmanniae,
The Radix Angelicae Dahuricae 5 ~ 7 parts,
Radix Trichosanthis 10 ~ 13 parts,
Radix Bupleuri 8 ~ 10 parts,
Caulis Polygoni Multiflori 4 ~ 6 parts,
Cortex Lycii 4 ~ 6 parts,
Os Draconis 3 ~ 4 parts,
3 ~ 4 parts, Fructus Jujubae,
Rhizoma Imperatae 2.5 ~ 3.5 parts,
Humus flava usta 1.3 ~ 2.2 parts.
A kind of medicament for the treatment of habitual epistaxis described above, in mass parts containing following composition:
Fructus Gardeniae 9 parts,
Rhizoma Imperatae 10 parts,
Rhizoma Zingiberis 15 parts,
Pollen Typhae carbon 9 parts,
5.5 parts, the Radix Rehmanniae,
The Radix Angelicae Dahuricae 6 parts,
Radix Trichosanthis 12 parts,
Radix Bupleuri 9 parts,
Caulis Polygoni Multiflori 5 parts,
Cortex Lycii 5 parts,
Os Draconis 3.5 parts,
3.5 parts, Fructus Jujubae,
Rhizoma Imperatae 3 parts,
Humus flava usta 1.8 parts.
A kind of preparation method for the treatment of the medicament of habitual epistaxis described above, the preparation process of the method is as follows:
The first step: decoct after Fructus Gardeniae, Rhizoma Imperatae, Rhizoma Zingiberis, Pollen Typhae carbon, the Radix Rehmanniae, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Bupleuri, Caulis Polygoni Multiflori, Cortex Lycii, Os Draconis, Fructus Jujubae, Rhizoma Imperatae, humus flava usta mixing, first time adds 6-8 times of water gaging, decocts 1-2h; Second time adds 6-8 times of water gaging, decocts 1-2h, merges twice decocting liquid, filtered by decocting liquid flame filter press;
Second step: add ethanol in filtrate after filtration, ethanol weight is 1-2 times of filtrate, filter after leaving standstill 16-20h, filtrate recycling ethanol, is then condensed into paste, then water is added, the weight of water is the 35-45% of first step Chinese crude drug gross mass, filters, filling-in and closing bottle by applying cap, sterilizing, obtains heat-clearing and toxic substances removing medicament.
In the first step described above, first time adds 7 times of water gagings, decocts 1.5h; Second time adds 7 times of water gagings, decocts 1.5h.
In second step described above, ethanol weight is 1.5 times of filtrate, filters after leaving standstill 18h.
In second step described above, the weight of water is 40% of first step Chinese crude drug gross mass.
beneficial effect:provided by the inventionly a kind ofly treat medicament of habitual epistaxis and preparation method thereof, this medicament can the habitual epistaxis of rapid healing, the function such as there is clearing away heat and promoting production of body fluid, removing heat from blood, clearind deficient heat, enrich blood, and there is certain sedative action, contribute to the sleep quality improving people.
Detailed description of the invention
embodiment 1
Treat a medicament for habitual epistaxis, to it is characterized in that in mass parts containing following composition: Fructus Gardeniae 4 parts, Rhizoma Imperatae 4 parts, Rhizoma Zingiberis 10 parts, Pollen Typhae carbon 5 parts, 3 parts, the Radix Rehmanniae, the Radix Angelicae Dahuricae 3 parts, Radix Trichosanthis 7 parts, Radix Bupleuri 6 parts, Caulis Polygoni Multiflori 2 parts, Cortex Lycii 2 parts, Os Draconis 1 part, 1 part, Fructus Jujubae, Rhizoma Imperatae 1 part, humus flava usta 0.5 part.
Treat a preparation method for the medicament of habitual epistaxis, the preparation process of the method is as follows:
The first step: decoct after Fructus Gardeniae, Rhizoma Imperatae, Rhizoma Zingiberis, Pollen Typhae carbon, the Radix Rehmanniae, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Bupleuri, Caulis Polygoni Multiflori, Cortex Lycii, Os Draconis, Fructus Jujubae, Rhizoma Imperatae, humus flava usta mixing, first time adds 6 times of water gagings, decocts 1h; Second time adds 6 times of water gagings, decocts 1h, merges twice decocting liquid, filtered by decocting liquid flame filter press;
Second step: add ethanol in filtrate after filtration, ethanol weight is 1 times of filtrate, filters, filtrate recycling ethanol after leaving standstill 16h, then be condensed into paste, then add water, the weight of water is 35% of first step Chinese crude drug gross mass, filters, filling-in and closing bottle by applying cap, sterilizing, obtains heat-clearing and toxic substances removing medicament.
embodiment 2
Treat a medicament for habitual epistaxis, to it is characterized in that in mass parts containing following composition: Fructus Gardeniae 13 parts, Rhizoma Imperatae 13 parts, Rhizoma Zingiberis 20 parts, Pollen Typhae carbon 14 parts, 8 parts, the Radix Rehmanniae, the Radix Angelicae Dahuricae 9 parts, Radix Trichosanthis 15 parts, Radix Bupleuri 13 parts, Caulis Polygoni Multiflori 8 parts, Cortex Lycii 8 parts, Os Draconis 6 parts, 6 parts, Fructus Jujubae, Rhizoma Imperatae 5 parts, humus flava usta 3 parts.
Treat a preparation method for the medicament of habitual epistaxis, the preparation process of the method is as follows:
The first step: decoct after Fructus Gardeniae, Rhizoma Imperatae, Rhizoma Zingiberis, Pollen Typhae carbon, the Radix Rehmanniae, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Bupleuri, Caulis Polygoni Multiflori, Cortex Lycii, Os Draconis, Fructus Jujubae, Rhizoma Imperatae, humus flava usta mixing, first time adds 8 times of water gagings, decocts 2h; Second time adds 8 times of water gagings, decocts 2h, merges twice decocting liquid, filtered by decocting liquid flame filter press;
Second step: add ethanol in filtrate after filtration, ethanol weight is 2 times of filtrate, filters, filtrate recycling ethanol after leaving standstill 20h, then be condensed into paste, then add water, the weight of water is 45% of first step Chinese crude drug gross mass, filters, filling-in and closing bottle by applying cap, sterilizing, obtains heat-clearing and toxic substances removing medicament.
embodiment 3
Treat a medicament for habitual epistaxis, to it is characterized in that in mass parts containing following composition: Fructus Gardeniae 6 parts, Rhizoma Imperatae 7 parts, Rhizoma Zingiberis 12 parts, Pollen Typhae carbon 6 parts, 4 parts, the Radix Rehmanniae, the Radix Angelicae Dahuricae 4 parts, Radix Trichosanthis 9 parts, Radix Bupleuri 7 parts, Caulis Polygoni Multiflori 3 parts, Cortex Lycii 3 parts, Os Draconis 2 parts, 2 parts, Fructus Jujubae, Rhizoma Imperatae 2 parts, humus flava usta 1 part.
Treat a preparation method for the medicament of habitual epistaxis, the preparation process of the method is as follows:
The first step: decoct after Fructus Gardeniae, Rhizoma Imperatae, Rhizoma Zingiberis, Pollen Typhae carbon, the Radix Rehmanniae, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Bupleuri, Caulis Polygoni Multiflori, Cortex Lycii, Os Draconis, Fructus Jujubae, Rhizoma Imperatae, humus flava usta mixing, first time adds 6 times of water gagings, decocts 1h; Second time adds 6 times of water gagings, decocts 1h, merges twice decocting liquid, filtered by decocting liquid flame filter press;
Second step: add ethanol in filtrate after filtration, ethanol weight is 1 times of filtrate, filters, filtrate recycling ethanol after leaving standstill 16h, then be condensed into paste, then add water, the weight of water is 35% of first step Chinese crude drug gross mass, filters, filling-in and closing bottle by applying cap, sterilizing, obtains heat-clearing and toxic substances removing medicament.
embodiment 4
Treat a medicament for habitual epistaxis, to it is characterized in that in mass parts containing following composition: Fructus Gardeniae 10 parts, Rhizoma Imperatae 11 parts, Rhizoma Zingiberis 16 parts, Pollen Typhae carbon 10 parts, 6 parts, the Radix Rehmanniae, the Radix Angelicae Dahuricae 7 parts, Radix Trichosanthis 13 parts, Radix Bupleuri 10 parts, Caulis Polygoni Multiflori 6 parts, Cortex Lycii 6 parts, Os Draconis 4 parts, 4 parts, Fructus Jujubae, Rhizoma Imperatae 3.5 parts, humus flava usta 2.2 parts.
Treat a preparation method for the medicament of habitual epistaxis, the preparation process of the method is as follows:
The first step: decoct after Fructus Gardeniae, Rhizoma Imperatae, Rhizoma Zingiberis, Pollen Typhae carbon, the Radix Rehmanniae, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Bupleuri, Caulis Polygoni Multiflori, Cortex Lycii, Os Draconis, Fructus Jujubae, Rhizoma Imperatae, humus flava usta mixing, first time adds 8 times of water gagings, decocts 2h; Second time adds 8 times of water gagings, decocts 2h, merges twice decocting liquid, filtered by decocting liquid flame filter press;
Second step: add ethanol in filtrate after filtration, ethanol weight is 2 times of filtrate, filters, filtrate recycling ethanol after leaving standstill 20h, then be condensed into paste, then add water, the weight of water is 45% of first step Chinese crude drug gross mass, filters, filling-in and closing bottle by applying cap, sterilizing, obtains heat-clearing and toxic substances removing medicament.
embodiment 5
Treat a medicament for habitual epistaxis, to it is characterized in that in mass parts containing following composition: Fructus Gardeniae 9 parts, Rhizoma Imperatae 10 parts, Rhizoma Zingiberis 15 parts, Pollen Typhae carbon 9 parts, 5.5 parts, the Radix Rehmanniae, the Radix Angelicae Dahuricae 6 parts, Radix Trichosanthis 12 parts, Radix Bupleuri 9 parts, Caulis Polygoni Multiflori 5 parts, Cortex Lycii 5 parts, Os Draconis 3.5 parts, 3.5 parts, Fructus Jujubae, Rhizoma Imperatae 3 parts, humus flava usta 1.8 parts.
Treat a preparation method for the medicament of habitual epistaxis, the preparation process of the method is as follows:
The first step: decoct after Fructus Gardeniae, Rhizoma Imperatae, Rhizoma Zingiberis, Pollen Typhae carbon, the Radix Rehmanniae, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Bupleuri, Caulis Polygoni Multiflori, Cortex Lycii, Os Draconis, Fructus Jujubae, Rhizoma Imperatae, humus flava usta mixing, first time adds 7 times of water gagings, decocts 1.5h; Second time adds 7 times of water gagings, decocts 1.5h, merges twice decocting liquid, filtered by decocting liquid flame filter press;
Second step: add ethanol in filtrate after filtration, ethanol weight is 1.5 times of filtrate, filters, filtrate recycling ethanol after leaving standstill 18h, then be condensed into paste, then add water, the weight of water is 40% of first step Chinese crude drug gross mass, filters, filling-in and closing bottle by applying cap, sterilizing, obtains heat-clearing and toxic substances removing medicament.
comparative example 1
Invention patent mandate notification number is the patent formulation of CN103893563A: 6g, Semen Benincasae 9g under glue pearl 9g, Flos Carthami 9g, Fructus Corni 10g, Cortex Moutan 10g, Radix Rehmanniae 20g, Rhizoma Dioscoreae 15g, river, Radix Notoginseng 6g, Radix Ophiopogonis 15g, Natrii Sulfas 9g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g.
Suffer from patient 60 people of habitual epistaxis, be equally divided into 6 groups, take respectively embodiment 1-5 and comparative example 1 medicament, every day 2 times, each 100mL, after taking 5 days, the therapeutic effect data of patient are as follows:
Claims (8)
1. treat a medicament for habitual epistaxis, to it is characterized in that in mass parts containing following composition:
Fructus Gardeniae 4 ~ 13 parts,
Rhizoma Imperatae 4 ~ 13 parts,
Rhizoma Zingiberis 10 ~ 20 parts,
Pollen Typhae carbon 5 ~ 14 parts,
3 ~ 8 parts, the Radix Rehmanniae,
The Radix Angelicae Dahuricae 3 ~ 9 parts,
Radix Trichosanthis 7 ~ 15 parts,
Radix Bupleuri 6 ~ 13 parts,
Caulis Polygoni Multiflori 2 ~ 8 parts,
Cortex Lycii 2 ~ 8 parts,
Os Draconis 1 ~ 6 part,
1 ~ 6 part, Fructus Jujubae,
Rhizoma Imperatae 1 ~ 5 part,
Humus flava usta 0.5 ~ 3 part.
2. a kind of medicament for the treatment of habitual epistaxis according to claim 1, to is characterized in that in mass parts containing following composition:
Fructus Gardeniae 6 ~ 11 parts,
Rhizoma Imperatae 7 ~ 12 parts,
Rhizoma Zingiberis 12 ~ 18 parts,
Pollen Typhae carbon 6 ~ 11 parts,
4 ~ 7 parts, the Radix Rehmanniae,
The Radix Angelicae Dahuricae 4 ~ 8 parts,
Radix Trichosanthis 9 ~ 14 parts,
Radix Bupleuri 7 ~ 11 parts,
Caulis Polygoni Multiflori 3 ~ 7 parts,
Cortex Lycii 3 ~ 7 parts,
Os Draconis 2 ~ 5 parts,
2 ~ 5 parts, Fructus Jujubae,
Rhizoma Imperatae 2 ~ 4 parts,
Humus flava usta 1 ~ 2.8 part.
3. a kind of medicament for the treatment of habitual epistaxis according to claim 1, to is characterized in that in mass parts containing following composition:
Fructus Gardeniae 8 ~ 10 parts,
Rhizoma Imperatae 9 ~ 11 parts,
Rhizoma Zingiberis 14 ~ 16 parts,
Pollen Typhae carbon 8 ~ 10 parts,
5 ~ 6 parts, the Radix Rehmanniae,
The Radix Angelicae Dahuricae 5 ~ 7 parts,
Radix Trichosanthis 10 ~ 13 parts,
Radix Bupleuri 8 ~ 10 parts,
Caulis Polygoni Multiflori 4 ~ 6 parts,
Cortex Lycii 4 ~ 6 parts,
Os Draconis 3 ~ 4 parts,
3 ~ 4 parts, Fructus Jujubae,
Rhizoma Imperatae 2.5 ~ 3.5 parts,
Humus flava usta 1.3 ~ 2.2 parts.
4. a kind of medicament for the treatment of habitual epistaxis according to claim 1, to is characterized in that in mass parts containing following composition:
Fructus Gardeniae 9 parts,
Rhizoma Imperatae 10 parts,
Rhizoma Zingiberis 15 parts,
Pollen Typhae carbon 9 parts,
5.5 parts, the Radix Rehmanniae,
The Radix Angelicae Dahuricae 6 parts,
Radix Trichosanthis 12 parts,
Radix Bupleuri 9 parts,
Caulis Polygoni Multiflori 5 parts,
Cortex Lycii 5 parts,
Os Draconis 3.5 parts,
3.5 parts, Fructus Jujubae,
Rhizoma Imperatae 3 parts,
Humus flava usta 1.8 parts.
5. a kind of preparation method for the treatment of the medicament of habitual epistaxis as claimed in claim 1, is characterized in that the preparation process of the method is as follows:
The first step: decoct after Fructus Gardeniae, Rhizoma Imperatae, Rhizoma Zingiberis, Pollen Typhae carbon, the Radix Rehmanniae, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Bupleuri, Caulis Polygoni Multiflori, Cortex Lycii, Os Draconis, Fructus Jujubae, Rhizoma Imperatae, humus flava usta mixing, first time adds 6-8 times of water gaging, decocts 1-2h; Second time adds 6-8 times of water gaging, decocts 1-2h, merges twice decocting liquid, filtered by decocting liquid flame filter press;
Second step: add ethanol in filtrate after filtration, ethanol weight is 1-2 times of filtrate, filter after leaving standstill 16-20h, filtrate recycling ethanol, is then condensed into paste, then water is added, the weight of water is the 35-45% of first step Chinese crude drug gross mass, filters, filling-in and closing bottle by applying cap, sterilizing, obtains heat-clearing and toxic substances removing medicament.
6. a kind of preparation method for the treatment of the medicament of habitual epistaxis according to claim 5, is characterized in that: in the described first step, first time adds 7 times of water gagings, decocts 1.5h; Second time adds 7 times of water gagings, decocts 1.5h.
7. a kind of preparation method for the treatment of the medicament of habitual epistaxis according to claim 5, is characterized in that: in described second step, ethanol weight is 1.5 times of filtrate, filters after leaving standstill 18h.
8. a kind of preparation method for the treatment of the medicament of habitual epistaxis according to claim 5, is characterized in that: in described second step, the weight of water is 40% of first step Chinese crude drug gross mass.
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Citations (4)
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|---|---|---|---|---|
| CN1600344A (en) * | 2003-09-24 | 2005-03-30 | 周道林 | Nasal bleeding pellet |
| CN101766804A (en) * | 2010-04-20 | 2010-07-07 | 泰一和浦（北京）中医药研究院有限公司 | Chinese herbal composite for epistaxis treatment and preparation method thereof |
| CN101791382A (en) * | 2010-04-09 | 2010-08-04 | 郑济 | Chinese herbal medicine combination for treating nasal bleeding |
| CN104258122A (en) * | 2014-09-09 | 2015-01-07 | 杨建平 | Traditional Chinese medicine for treating nosebleed |
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2015
- 2015-04-15 CN CN201510175472.5A patent/CN104815303A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1600344A (en) * | 2003-09-24 | 2005-03-30 | 周道林 | Nasal bleeding pellet |
| CN101791382A (en) * | 2010-04-09 | 2010-08-04 | 郑济 | Chinese herbal medicine combination for treating nasal bleeding |
| CN101766804A (en) * | 2010-04-20 | 2010-07-07 | 泰一和浦（北京）中医药研究院有限公司 | Chinese herbal composite for epistaxis treatment and preparation method thereof |
| CN104258122A (en) * | 2014-09-09 | 2015-01-07 | 杨建平 | Traditional Chinese medicine for treating nosebleed |
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| 任雅丽: ""茅根止血汤治疗鼻出血57例"", 《陕西中医》 * |
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Application publication date: 20150805 |