CN104815127A - Externally applied preparation for treating lymphnoditis and preparation method thereof - Google Patents

Externally applied preparation for treating lymphnoditis and preparation method thereof Download PDF

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CN104815127A
CN104815127A CN201510239317.5A CN201510239317A CN104815127A CN 104815127 A CN104815127 A CN 104815127A CN 201510239317 A CN201510239317 A CN 201510239317A CN 104815127 A CN104815127 A CN 104815127A
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herba
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folium
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范道锋
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Abstract

The invention discloses an externally applied preparation for treating lymphnoditis. The externally applied preparation is prepared from the following main raw materials in parts by weight: 12-16 parts of dandelion, 8-12 parts of radix ampelopsis, 9-13 parts of Crotalaria ferruginea Grah, 11-15 parts of bamboo iris, 12-17 parts of radix bupleuri, 10-14 parts of Erigeron annuus, 8-12 parts of trichosanthes palmate, 10-13 parts of leaf of Chinese Hibiscus, 14-18 parts of angelica, 11-16 parts of Lepidogrammitis drymoglossoides Ching, 8-14 parts of Indigofera tinctoria, 10-14 parts of Dracocephalum heterophyllum and 9-12 parts of purslane. The externally applied preparation is applied to the surface affected part to reach the subcutaneous tissue through the skin permeation; the partial blood circulation is promoted, the swell and inflammation effects are reached and the therapeutical effect on lymphnoditis is good.

Description

The externally dressing for the treatment of lymphadenitis and method for making
Technical field
The present invention relates to traditional Chinese medicine field, especially relate to a kind of externally dressing and method for making for the treatment of lymphadenitis.
Background technology
Lymphadenitis is the nonspecific inflammation that the Acute and chronic inflammation in drain region belonging to lymph node involves caused by lymph node, and the infection of stomach wall as above in upper limb, mammary gland, thoracic wall, back and umbilicus causes armpit lymphadenitis; , pars inguinalis lymphadenitis can be there is in the infection of the following stomach wall of lower limb, umbilicus, perineum and buttocks; Head, face, oral cavity, cervical region and shoulder infect, under causing jaw and the lymphadenitis of cervical region.According to onset emergency, course of disease length, lymphadenitis can be divided into acute and chronic lymphadenitis.Acute lymphadenitis is often secondary to other pyogenic infection disease, the rapid enlargement of lymph node, tenderness.If patient's resistance is comparatively strong, can without General Symptoms, do not need treatment can spontaneous recovery yet.Comparatively severe one local red and swollen heat pain, very with symptoms such as fear of cold heating, headaches, by anti-inflammation treatment timely, redness can disappear, but sometimes because inflammation causes hamartoplasia, can leave over a little scleroma.If inflammation fails to control in time, be diffused into lymph node and adhesion mutually, severe patient can form abscess.As treated not in time, septicemia can be caused.Chronic lymphadenitis: regional glandular enlargement, at first in common site, as: under jaw, under chin, lymphoglandulae cervicales profundae superiores enlargement, tenderness, circumference be clear, movable without adhesion.The state of an illness continues development, and when lymph node inflammation involves surrounding tissue, lymph node palpation inertia, the pain increased, is further development of adenogenous cellulitis.Chronic lymphadenitis has relieving distension history repeatedly, 2-3 lymph node, matter medium hardness, movable, tenderness.
The traditional Chinese medical science is thought, lymphadenitis belongs to " carbuncle " category, many by the heresy experiencing the six climate exopathogens such as wind heat noxious dampness, or have internal organs accumulated heat, multiple through golden sword wound or the infection poison heresy that excoriates, or throw off restraint food cream nest savoury, inside there is damp and hot fire-toxin, cause QI and blood to be filled between skin and flesh by malicious heresy, then refine liquid and become expectorant, expectorant poison is cloudy mutually, lumps and swells.If pathogenic wind toxic phlegm-fire is attacked, then send out as " cervical carbuncle ", if the cohesion of liver stomach accumulated heat, then send out as " carbuncle of the axilla ", if the unrestrained heat bet of liver and gall, then send out as " acute inguinal pyogenic lymphadenitis ".Lymphadenitis is secondary to other pyogenic infection focuses, is that the lymph node invading affiliated area along lymphatic vessel by suppurative bacterium causes, often there will be the symptom of lymphadenectasis.In daily life, often have people after catching a cold or other infects, after cervical region, ear, there is as glass bead size tuberosity in oxter or groin place, and locally red and swollen tenderness, hard by it, lymphadenitis that Here it is.If the state of an illness continues development, when lymph node inflammation involves surrounding tissue, cause that the pain increased, be further development of adenogenous cellulitis; If inflammation fails to control in time, be diffused into lymph node and adhesion mutually, finally form abscess, severe patient also can cause septicemia.
In the method for existing Chinese traditional treatment lymphadenitis, publication number CN 103479980 A(application number 201310431398.X) patent discloses a kind of plaster for the treatment of acute lymphadenitis, the weight proportion of its each raw material components is: Hirudo 10-14, Herba Andrographis 13-17, Radix Aconiti 10-14, Centranthera grandiflora Benth 6-10, Cortex Cinnamomi 13-17, Semen Coicis 6-10, Flos Rosae Chinensis 4-8, Myrrha 4-8, Herba Asari 1-5, Herba Verbenae 4-8, Rhizoma Zingiberis 6-10, Turpinia arguta Seem 10-14, Moschus 1-5, Asplenium normale Don 6-10, LUBIANHUANG 13-17.Publication number CN 103463523 A(application number 201310367490.4) the one that patent discloses treat heat toxin exuberance type oxter acute suppurative lymphadenitis Chinese medicine, extracting honeysuckle 9 grams, Fructus Forsythiae 6 grams, Herba Violae 3 grams, Herba Taraxaci 6 grams, Folium Isatidis 12 grams, Radix Isatidis 12 grams, Herba Patriniae 9 grams, Herba Houttuyniae 3 grams, Caulis Sargentodoxae 6 grams, Rhizoma Belamcandae 9 grams, Lasiosphaera Seu Calvatia 6 grams, Calyx Seu Fructus Physalis 6 grams, Radix Sophorae Tonkinensis 3 grams, Fructus Canarii 6 grams, Radix Ampelopsis 6 grams, Radix Rhapontici 9 grams, Rhizoma Osmundae 0.5 gram, Rhizoma Smilacis Glabrae 6 grams, Rhizoma Paridis 0.5 gram, Rhizoma Bistortae 0.5 gram, Herba Portulacae 6 grams, Herba Lobeliae Chinensis 3 grams, Herba Potentillae Discoloris 6 grams, Herba Andrographis 6 grams, Radix Berberidis 9 grams, Herba Saxifragae 1 gram, Retinervus Luffae Fructus 3 grams, Radix seu Herba Spiranthis Lanceae 6 grams, Radix Scutellariae 9 grams, Rhizoma Coptidis 6 grams, Cortex Phellodendri 9 grams, Cortex Moutan 6 grams and 9 grams, Radix Glycyrrhizae, above 33 taste Chinese medicines are put into 1800 ml waters, soak 30 minutes, then fried 30 minutes of slow fire, filter and remove residue is boiled medicine liquid 390 milliliters altogether, fried medicinal liquid is the Chinese medicine for the treatment of heat toxin exuberance type oxter acute suppurative lymphadenitis.Publication number CN 103638182 A(application number 201310615773.6) patent discloses a kind of Chinese medicine for outer use for the treatment of acute lymphadenitis, be made up of the raw material of Chinese medicine of following parts by weight: Mirabilitum crystallina 5 parts, Herba Duchesneae Indicae 4 parts, Herba Andrographis 2 parts, Herba veronicastri villosuli 3 parts, Borneolum Syntheticum 1 part.
At present, conventional therapy lymphadenitis is mainly based on doctor trained in Western medicine, and western medical treatment generally adopts antibiotic etc, and the course for the treatment of is long, and side effect is large, and easily the symptoms such as irritated occur, long-term taking can cause lesions of liver and kidney.How indefinite the curative effect of existing Chinese medicine is.
Summary of the invention
An object of the present invention is to provide a kind of externally dressing for the treatment of lymphadenitis, adopt Chinese crude drug comparatively common in the localities as raw material, there is the effect of dissipating phlegm and resolving masses, heat-clearing and toxic substances removing, soothing the liver eliminating stagnation, clearing away heat-damp and promoting diuresis, promoting blood circulation and detumescence, have good curative effect to lymphadenitis.Another object is just to provide the preparation method of above-mentioned externally dressing.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The externally dressing for the treatment of lymphadenitis, takes off the primary raw material stating weight proportion and is prepared from: Herba Taraxaci 12-16 part; Radix Ampelopsis 8-12 part; Herba Crotalariae Ferrugineae 9-13 part; Rhizoma Tupistrae Wattii 11-15 part; Radix Bupleuri 12-17 part; Herba Erigerontis Annui 10-14 part; Radix Stephaniae Cepharanthae 8-12 part; Folium Hibisci Rosae-Sinensis 10-13 part; Radix Angelicae Sinensis 14-18 part; Lepidogrammitis drymoglossoides (Bak.) Ching 11-16 part; Folium et Caulis Indigoferae Tinctoriae 8-14 part; Spend very sweet 10-14 part in vain; Herba Portulacae 9-12 part.
The externally dressing for the treatment of lymphadenitis, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Herba Taraxaci 13-15 part; Radix Ampelopsis 9-11 part; Herba Crotalariae Ferrugineae 10-12 part; Rhizoma Tupistrae Wattii 12-14 part; Radix Bupleuri 14-16 part; Herba Erigerontis Annui 11-13 part; Radix Stephaniae Cepharanthae 9-11 part; Folium Hibisci Rosae-Sinensis 11-12 part; Radix Angelicae Sinensis 15-17 part; Lepidogrammitis drymoglossoides (Bak.) Ching 12-15 part; Folium et Caulis Indigoferae Tinctoriae 10-12 part; Spend very sweet 11-13 part in vain; Herba Portulacae 10-11 part.
The externally dressing for the treatment of lymphadenitis, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Herba Taraxaci 14 parts; Radix Ampelopsis 10 parts; Herba Crotalariae Ferrugineae 11 parts; Rhizoma Tupistrae Wattii 13 parts; Radix Bupleuri 15 parts; Herba Erigerontis Annui 12 parts; Radix Stephaniae Cepharanthae 10 parts; Folium Hibisci Rosae-Sinensis 11.5 parts; Radix Angelicae Sinensis 16 parts; Lepidogrammitis drymoglossoides (Bak.) Ching 13 parts; Folium et Caulis Indigoferae Tinctoriae 11 parts; Spend very sweet 12 parts in vain; Herba Portulacae 10.5 parts.
The preparation method of above-mentioned externally dressing, step is as follows:
(1) Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae are smashed, be placed in crock, add white vinegar, stir evenly, sealing, put shady and cool place 10-15 days, dry, pulverize, cross 110-130 mesh sieve;
(2) fresh Herba Portulacae is smashed to pieces, be squeezed into juice;
(3) by Herba Taraxaci, Lepidogrammitis drymoglossoides (Bak.) Ching with spend very sweet oven dry in vain, grind as smalls, cross 100-140 mesh sieve;
(4) by Radix Bupleuri and Chinese angelica slicing, be placed in marmite, decoct with water 40-50 minute, add Herba Crotalariae Ferrugineae, Herba Erigerontis Annui, Folium Hibisci Rosae-Sinensis and Folium et Caulis Indigoferae Tinctoriae, continue decoction twice, each decoction 30-40 minute, merging filtrate, being condensed into relative density is 1.10-1.20(25 DEG C) thick paste;
(5) join in step (4) gained thick paste by step (2) gains, mix homogeneously, add step (1) and step (3) gained powder, mixing, makes externally dressing.
The preparation method of above-mentioned externally dressing, preferred scheme is: the consumption of the preferred white vinegar of step (1) is the 40%-50% of Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae gross mass, the consumption being more preferably white vinegar be Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae gross mass 45%.
The preparation method of above-mentioned externally dressing, preferred scheme is: step (1) is preferred crosses 116-124 mesh sieve, is more preferably 120 mesh sieves.
The preparation method of above-mentioned externally dressing, preferred scheme is: step (3) is preferred crosses 110-130 mesh sieve, is more preferably 120 mesh sieves.
The preparation method of above-mentioned externally dressing, preferred scheme is: step (4) preferably decocts with water 43-47 minute, is more preferably and decocts with water 45 minutes.
The preparation method of above-mentioned externally dressing, preferred scheme is: step (4) is preferably each decocts 33-37 minute, is more preferably each decoction 35 minutes.
The preparation method of above-mentioned externally dressing, preferred scheme is: it is 1.13-1.17(25 DEG C that step (4) is preferably condensed into relative density) thick paste, being more preferably and being condensed into relative density is 1.15(25 DEG C) thick paste.
using method: for making the present invention reach optimum therapeuticing effect, this externally dressing, by affected part wiped clean, is applied to affected part by the ethanol with 80%, and every day is coated with 2-3 time, within 3 days, is a course for the treatment of.
The pharmacological effect of each crude drug is respectively:
Herba Taraxaci: bitter in the mouth, sweet, cold in nature.Return liver, stomach warp.For feverfew Herba Taraxaci, alkali ground Herba Taraxaci or the dry herb belonging to several plants together.Containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin.There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, enterodynia, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Radix Ampelopsis: bitter in the mouth, cold nature.GUIXIN, stomach warp.For the dried root of vitaceae Radix Ampelopsis.Quintessence oil heat-clearing and toxic substances removing, effect of eliminating carbuncle eliminating stagnation.For carbuncle carbuncle on the back, furuncle, scrofula, burn due to hot liquid or fire.
Herba Crotalariae Ferrugineae: bitter in the mouth, micro-acid, property is put down.Return lung, liver, kidney channel.For the false ground of pulse family Crotalaria plant is blue or the root of bar leaf Herba crotalariae mucronatae or herb.Have nourishing the liver and kidney, cough-relieving is breathed heavily, effect of dampness removing, for tinnitus, deaf, the vertigo, seminal emission, menorrhagia, leucorrhea, chronic cough expectorant blood, asthma, nephritis, dysuria, tonsillitis, parotitis, furuncle swelling toxin.
Rhizoma Tupistrae Wattii: acrid in the mouth, micro-hardship, cold in nature.For the rhizome of Liliaceae Tupistra plant Tupistra wattii.Containing Tupistra wattii glycoside unit A, neolliogenin D.There is heat-clearing and toxic substances removing, removing heat from blood, effect of dissipating blood stasis.For cold anemopyretic, cough pharyngalgia, acute mastitis, conjunctival congestion, traumatic injury, stomachache is spitted blood, traumatic hemorrhage.
Radix Bupleuri: bitter in the mouth, cold nature.Return liver, gallbladder meridian.For the dry root of umbelliferae bupleurum or Radix Bupeuri Scorzonerfolii..There is reconciling superficies and interior, soothing the liver, effect of yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.
Herba Erigerontis Annui: sweet in the mouth, hardship, cool in nature.Return stomach, large intestine channel.For the herb of feverfew Herba Erigerontis Annui.Containing pyromeconic acid, Quercetin, the intoxicated sour glycoside of apigenin-7-glucose, apigenin.Have heat-clearing and toxic substances removing, help digestion antidiarrheal, effect of malaria.For acute gastroenteritis, dyspepsia, enteritis, diarrhea, infectious hepatitis, lymphadenitis, hematuria, malaria; Gingivitis is controlled in external, venom.
Radix Stephaniae Cepharanthae: bitter in the mouth, pungent, cool in nature.Attach to the lung and stomach meridians.For the tuber of Menispermaceae stephania plant Radix Stephaniae Cepharanthae.Containing alkaloid 1.79-1.88%.Root contains Radix Stephaniae Cepharanthae alkali, isosinomenine cycleanine, berbamine, homoaromoline, gold thread silks Testudinis amine, cepharanoline, mufangchine, sinomenine, quinine, papaverine, codeine, morphine, berberine.There is heat-clearing and toxic substances removing, wind-expelling pain-stopping, effect of cooling blood for hemostasis.For laryngopharynx swelling and pain, pyretic toxicity carbuncle, rheumatic arthralgia, stomachache, dysentery, spits blood, epistaxis, traumatic hemorrhage.
Folium Hibisci Rosae-Sinensis: sweet in the mouth, property is put down.GUIXIN, Liver Channel.For the leaf of Malvaceae Hibiscus plant Hibiscus rosasinensis.Containing C16-C32 hydrocarbons, wherein C17, C23, C25, C31 hydrocarbons is main, C21-C30 high fatty alcohol, wherein based on C26, iso-C28, iso-C30, higher alcohol, C8-C28 fatty acid, wherein based on C8, C12, C14, C16, C18:2, sterculic acid, malvalic acid, Pu Fuzhou, cupreol, also containing the Hibiscus syriacus L. phlegmatic temperament-RL of tool anticomplementary activity.There is the diarrhea of heat type that disappears wet, effect of removing toxic substances.For leucorrhea, stranguria, furuncle swelling toxin, mumps, acute mastitis, lymphadenitis.
Radix Angelicae Sinensis: sweet in the mouth, pungent, micro-hardship, warm in nature.Return liver, the heart, spleen channel.For the dry root of umbelliferae angelica.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Lepidogrammitis drymoglossoides (Bak.) Ching: sweet in the mouth, micro-hardship, cool in nature.Return liver, stomach, urinary bladder channel.For the herb of Polypodiaceae dominoes Cyclosorus plant Drymoglossum Herba Drymoglossi.Containing flavone, alkaloid, sterol, aminoacid, sugar etc.There is heat-clearing and toxic substances removing, relieving stranguria by diuresis.Effect of removing heat from blood repercussive.For mumps, laryngopharynx swelling and pain, mass in the abdomen, tympanites, stranguria with turbid discharge, edema, spits blood, epistaxis, hematuria, furuncle carbuncle, scrofula, traumatic injury.
Folium et Caulis Indigoferae Tinctoriae: mildly bitter flavor, cold in nature.For the stem and leaf of pulse family magnolia Folium et Caulis Indigoferae Tinctoriae.Containing indigo glycoside, generate 3-hydroxyindole after hydrolysis, the oxidation of this composition generates indigo.There is heat-clearing and toxic substances removing, effect of cooling blood for hemostasis.For encephalitis B, parotitis, acute pharyngolaryngitis, lymphadenitis, conjunctival congestion, aphtha, carbuncle furuncle, erysipelas, scabies, worm venom, spits blood.
Spend in vain very sweet: bitter in the mouth, pungent, cold in nature.Return Liver Channel.For the herb of Labiatae dragonhead dracocephalum heterophyllum.Containing volatile oil 0.3%-0.5%, there are flavonoid, coumarin, lactone, phenols, organic acid through prerun, the reaction of reducing substances.There is purging liver-fire, the effect of eliminating stagnation of regulating the flow of vital energy.For headache, mist, jaundice, chest distress and palpitation symptoms, stomachache, tuberculous lymphadenitis, thyromegaly, oral ulcer.
Herba Portulacae: sour in the mouth, cold in nature.Return liver, large intestine channel.For the dry aerial parts of portulacaceous plant Herba Portulacae.There is heat-clearing and toxic substances removing, effect of cooling blood for hemostasis.For toxic-heat and blood stasis, carbuncle furuncle, eczema, erysipelas, snake bite and insect sting, has blood in stool, hemorrhoidal bleeding, metrostaxis.
Beneficial effect of the present invention is mainly reflected in:
1, externally dressing of the present invention is applied to body surface affected part, medicine reaches subcutaneous tissue by Cutaneous permeation, promotes local blood circulation, reaches the effect of detumescence antiinflammatory, has fabulous therapeutical effect to lymphadenitis.
2, after externally dressing break-through skin of the present invention and mucosa, enter body circulation through blood vessel or lymphatic vessel, systemic medication effect can be produced, reach the object of thoroughly treatment lymphadenitis.
3, externally dressing of the present invention is based on the principle of Chinese traditional treatment lymphadenitis, selects common medical material, cheap and easy to operate.
4, externally dressing of the present invention is by the local penetration of medicine, thus the effective ingredient of medicine is directly sent to lesions position, avoids the drug effect of oral medicine faint and cause larger side effect to health.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the externally dressing for the treatment of lymphadenitis, takes off and states primary raw material and be prepared from (getting 50g for every part): Herba Taraxaci 12 parts; Radix Ampelopsis 8 parts; Herba Crotalariae Ferrugineae 9 parts; Rhizoma Tupistrae Wattii 11 parts; Radix Bupleuri 12 parts; Herba Erigerontis Annui 10 parts; Radix Stephaniae Cepharanthae 8 parts; Folium Hibisci Rosae-Sinensis 10 parts; Radix Angelicae Sinensis 14 parts; Lepidogrammitis drymoglossoides (Bak.) Ching 11 parts; Folium et Caulis Indigoferae Tinctoriae 8 parts; Spend very sweet 10 parts in vain; Herba Portulacae 9 parts.
The externally dressing preparation process for the treatment of lymphadenitis is as follows:
(1) Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae are smashed, be placed in crock, add white vinegar, stir evenly, sealing, put shady and cool place 10 days, dry, pulverize, cross 110 mesh sieves;
(2) fresh Herba Portulacae is smashed to pieces, be squeezed into juice;
(3) by Herba Taraxaci, Lepidogrammitis drymoglossoides (Bak.) Ching with spend very sweet oven dry in vain, grind as smalls, cross 100 mesh sieves;
(4) by Radix Bupleuri and Chinese angelica slicing, be placed in marmite, decoct with water 40 minutes, add Herba Crotalariae Ferrugineae, Herba Erigerontis Annui, Folium Hibisci Rosae-Sinensis and Folium et Caulis Indigoferae Tinctoriae, continue decoction twice, each to decoct 30 minutes, merging filtrate, being condensed into relative density is 1.10(25 DEG C) thick paste;
(5) join in step (4) gained thick paste by step (2) gains, mix homogeneously, add step (1) and step (3) gained powder, mixing, makes externally dressing.
Using method: this externally dressing, by affected part wiped clean, is applied to affected part by the ethanol with 80%, every day is coated with 2-3 time, within 3 days, is a course for the treatment of.
embodiment 2the externally dressing for the treatment of lymphadenitis, takes off and states primary raw material and be prepared from (getting 20g for every part): Herba Taraxaci 16 parts; Radix Ampelopsis 12 parts; Herba Crotalariae Ferrugineae 13 parts; Rhizoma Tupistrae Wattii 15 parts; Radix Bupleuri 17 parts; Herba Erigerontis Annui 14 parts; Radix Stephaniae Cepharanthae 12 parts; Folium Hibisci Rosae-Sinensis 13 parts; Radix Angelicae Sinensis 18 parts; Lepidogrammitis drymoglossoides (Bak.) Ching 16 parts; Folium et Caulis Indigoferae Tinctoriae 14 parts; Spend very sweet 14 parts in vain; Herba Portulacae 12 parts.
The externally dressing preparation process for the treatment of lymphadenitis is as follows:
(1) Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae are smashed, be placed in crock, add white vinegar, stir evenly, sealing, put shady and cool place 15 days, dry, pulverize, cross 130 mesh sieves;
(2) fresh Herba Portulacae is smashed to pieces, be squeezed into juice;
(3) by Herba Taraxaci, Lepidogrammitis drymoglossoides (Bak.) Ching with spend very sweet oven dry in vain, grind as smalls, cross 140 mesh sieves;
(4) by Radix Bupleuri and Chinese angelica slicing, be placed in marmite, decoct with water 50 minutes, add Herba Crotalariae Ferrugineae, Herba Erigerontis Annui, Folium Hibisci Rosae-Sinensis and Folium et Caulis Indigoferae Tinctoriae, continue decoction twice, each to decoct 40 minutes, merging filtrate, being condensed into relative density is 1.20(25 DEG C) thick paste;
(5) join in step (4) gained thick paste by step (2) gains, mix homogeneously, add step (1) and step (3) gained powder, mixing, makes externally dressing.
Using method: this externally dressing, by affected part wiped clean, is applied to affected part by the ethanol with 80%, every day is coated with 2-3 time, within 3 days, is a course for the treatment of.
model case oneland XX, man, 12 years old, people from Heze city of Shandong province.Before 1 wheat harvesting period, find cervical lymph node enlargement, both sides about have 2-4, about Semen arachidis hypogaeae size, and heating, appears in companion's pain then, and most high fever 39 DEG C, burns after oral antipyretic and move back, but repeatedly generate heat, and drop 3 days is without being clearly better.So remove examination in hospital, routine blood test: WBC:13.2X10 9/ L, HB:123G/L, be diagnosed as lymphadenitis.Treat, heating is eased, but lymphadenectasis is without alleviation.
Use the present invention to treat the externally dressing of lymphadenitis, after 2 courses for the treatment of of the drug of topical application, cervical pain is eased, and part lymph node reduces a lot.After reducing 1 course for the treatment of of use, cervical region is without keenly feeling, without all untoward reaction during medication.
embodiment 3the externally dressing for the treatment of lymphadenitis, takes off and states primary raw material and be prepared from (getting 50g for every part): Herba Taraxaci 13 parts; Radix Ampelopsis 9 parts; Herba Crotalariae Ferrugineae 10 parts; Rhizoma Tupistrae Wattii 12 parts; Radix Bupleuri 14 parts; Herba Erigerontis Annui 11 parts; Radix Stephaniae Cepharanthae 9 parts; Folium Hibisci Rosae-Sinensis 11 parts; Radix Angelicae Sinensis 15 parts; Lepidogrammitis drymoglossoides (Bak.) Ching 12 parts; Folium et Caulis Indigoferae Tinctoriae 10 parts; Spend very sweet 11 parts in vain; Herba Portulacae 10 parts.
The externally dressing preparation process for the treatment of lymphadenitis is as follows:
(1) Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae are smashed, be placed in crock, add white vinegar, stir evenly, sealing, put shady and cool place 11 days, dry, pulverize, cross 116 mesh sieves;
(2) fresh Herba Portulacae is smashed to pieces, be squeezed into juice;
(3) by Herba Taraxaci, Lepidogrammitis drymoglossoides (Bak.) Ching with spend very sweet oven dry in vain, grind as smalls, cross 110 mesh sieves;
(4) by Radix Bupleuri and Chinese angelica slicing, be placed in marmite, decoct with water 43 minutes, add Herba Crotalariae Ferrugineae, Herba Erigerontis Annui, Folium Hibisci Rosae-Sinensis and Folium et Caulis Indigoferae Tinctoriae, continue decoction twice, each to decoct 33 minutes, merging filtrate, being condensed into relative density is 1.13(25 DEG C) thick paste;
(5) join in step (4) gained thick paste by step (2) gains, mix homogeneously, add step (1) and step (3) gained powder, mixing, makes externally dressing.
Using method: this externally dressing, by affected part wiped clean, is applied to affected part by the ethanol with 80%, every day is coated with 2-3 time, within 3 days, is a course for the treatment of.
embodiment 4the externally dressing for the treatment of lymphadenitis, takes off and states primary raw material and be prepared from (getting 20g for every part): Herba Taraxaci 15 parts; Radix Ampelopsis 11 parts; Herba Crotalariae Ferrugineae 12 parts; Rhizoma Tupistrae Wattii 14 parts; Radix Bupleuri 16 parts; Herba Erigerontis Annui 13 parts; Radix Stephaniae Cepharanthae 11 parts; Folium Hibisci Rosae-Sinensis 12 parts; Radix Angelicae Sinensis 17 parts; Lepidogrammitis drymoglossoides (Bak.) Ching 15 parts; Folium et Caulis Indigoferae Tinctoriae 12 parts; Spend very sweet 13 parts in vain; Herba Portulacae 11 parts.
The externally dressing preparation process for the treatment of lymphadenitis is as follows:
(1) Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae are smashed, be placed in crock, add white vinegar, stir evenly, sealing, put shady and cool place 14 days, dry, pulverize, cross 124 mesh sieves;
(2) fresh Herba Portulacae is smashed to pieces, be squeezed into juice;
(3) by Herba Taraxaci, Lepidogrammitis drymoglossoides (Bak.) Ching with spend very sweet oven dry in vain, grind as smalls, cross 130 mesh sieves;
(4) by Radix Bupleuri and Chinese angelica slicing, be placed in marmite, decoct with water 47 minutes, add Herba Crotalariae Ferrugineae, Herba Erigerontis Annui, Folium Hibisci Rosae-Sinensis and Folium et Caulis Indigoferae Tinctoriae, continue decoction twice, each to decoct 37 minutes, merging filtrate, being condensed into relative density is 1.17(25 DEG C) thick paste;
(5) join in step (4) gained thick paste by step (2) gains, mix homogeneously, add step (1) and step (3) gained powder, mixing, makes externally dressing.
Using method: this externally dressing, by affected part wiped clean, is applied to affected part by the ethanol with 80%, every day is coated with 2-3 time, within 3 days, is a course for the treatment of.
model case twoyellow XX, man, 43 years old, people from Rizhao City, Shandong Province.Patient's emaciated physique, heating do not move back lasting more than 10 days.Under neck jaw, there are two lumps as large in Semen Viciae fabae on both sides, cervical region Visible lumps when swallowing, and all occur pain around the ear-lobe of right side, and difficulty in opening mouth, have a size to be about the similar lymph node of 8mm in palpation lump, matter is hard, have light tenderness, clear border, there is multiple lump differed in size at other position, through examination in hospital, examine as lymphadenitis, give anti-inflammatory agent and antitubercular agent treatment, symptom is without obvious alleviation, heating is not moved back, and diet reduces, and day by day becomes thin.
When using the present invention to treat 2 courses for the treatment of of externally dressing of lymphadenitis, the lump of patient's cervical region obviously reduces, and pain obviously alleviates, and spirit takes a favorable turn.Use 2 courses for the treatment of again, sense of swelling and ache disappears, and the basic cancellation of lump, reaches clinical recovery.Without all untoward reaction during medication.
embodiment 5the externally dressing for the treatment of lymphadenitis, takes off and states primary raw material and be prepared from (getting 10g for every part): Herba Taraxaci 14 parts; Radix Ampelopsis 10 parts; Herba Crotalariae Ferrugineae 11 parts; Rhizoma Tupistrae Wattii 13 parts; Radix Bupleuri 15 parts; Herba Erigerontis Annui 12 parts; Radix Stephaniae Cepharanthae 10 parts; Folium Hibisci Rosae-Sinensis 11.5 parts; Radix Angelicae Sinensis 16 parts; Lepidogrammitis drymoglossoides (Bak.) Ching 13 parts; Folium et Caulis Indigoferae Tinctoriae 11 parts; Spend very sweet 12 parts in vain; Herba Portulacae 10.5 parts.
The externally dressing preparation process for the treatment of lymphadenitis is as follows:
(1) Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae are smashed, be placed in crock, add white vinegar, stir evenly, sealing, put shady and cool place 13 days, dry, pulverize, cross 120 mesh sieves;
(2) fresh Herba Portulacae is smashed to pieces, be squeezed into juice;
(3) by Herba Taraxaci, Lepidogrammitis drymoglossoides (Bak.) Ching with spend very sweet oven dry in vain, grind as smalls, cross 120 mesh sieves;
(4) by Radix Bupleuri and Chinese angelica slicing, be placed in marmite, decoct with water 45 minutes, add Herba Crotalariae Ferrugineae, Herba Erigerontis Annui, Folium Hibisci Rosae-Sinensis and Folium et Caulis Indigoferae Tinctoriae, continue decoction twice, each to decoct 35 minutes, merging filtrate, being condensed into relative density is 1.15(25 DEG C) thick paste;
(5) join in step (4) gained thick paste by step (2) gains, mix homogeneously, add step (1) and step (3) gained powder, mixing, makes externally dressing.
Using method: this externally dressing, by affected part wiped clean, is applied to affected part by the ethanol with 80%, every day is coated with 2-3 time, within 3 days, is a course for the treatment of.
test example: the clinical practice of the externally dressing (embodiment 5) of gained treatment lymphadenitis of the present invention: in March ,-2011 in May, 2010, screening 250 routine patients, wherein women 123 example, male 127 example; Max age 68 years old, minimal ages 9 years old; 9-20 year 38 people, 20-35 year 65 people, 36-50 year 68 people, 51-68 year 79 people.Be divided into experimental group and matched group two groups (wherein experimental group has 150 people, and matched group has 100 people) at random.Experimental group uses the present invention to treat the externally dressing of lymphadenitis, and using method is: this externally dressing, by affected part wiped clean, is applied to affected part by the ethanol with 80%, and every day is coated with 2-3 time, within 3 days, is a course for the treatment of.Matched group uses other medicine (as giant silkworm sheet, Wuhaiyingliu ball etc.), and wherein, giant silkworm sheet: oral, a 0.6-1.5g, a secondary amounts must not more than 3g, 3 times on the one.Wuhaiyingliu ball: oral, 1 ball, 2 times on the one.Curative effect situation criterion: cure: the malaise symptoms such as pain disappear, lymph node cancellation.Effective: the malaise symptoms such as pain are obviously alleviated, lymph node obviously reduces.Invalid: the various malaise symptoms such as pain is unchanged, lymph node is even more serious without reduction.Result is as shown in the table:
Table 1
therapeutic effect: use the present invention to treat healing 121 people of the externally dressing of lymphadenitis, cure rate is up to 80.67%, and effective 26 people, obvious effective rate 17.33%, invalid 3 people, effective percentage reaches 98 %.And using healing 37 people of other products, cure rate only reaches 37%, effective 46 people, and obvious effective rate is 46%, and invalid number is but up to 17 people, and inefficiency reaches 17%, effective percentage only 83%.Can find out: the successful using the present invention to treat the externally dressing of lymphadenitis is better than the effect of other products.The externally dressing that the present invention treats lymphadenitis has significant curative effect to lymphadenitis, by the local penetration of medicine, thus the effective ingredient of medicine is directly sent to lesions position, avoids the drug effect of oral medicine faint and cause larger side effect to health.Compared with the medicine for the treatment of lymphadenitis with other, side effect is little, and batching is all choose more common medical material, cheap, and ordinary people can life-time service, and the pain not only decreased on health also reduces pecuniary burden.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. treat the externally dressing of lymphadenitis, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Herba Taraxaci 12-16 part; Radix Ampelopsis 8-12 part; Herba Crotalariae Ferrugineae 9-13 part; Rhizoma Tupistrae Wattii 11-15 part; Radix Bupleuri 12-17 part; Herba Erigerontis Annui 10-14 part; Radix Stephaniae Cepharanthae 8-12 part; Folium Hibisci Rosae-Sinensis 10-13 part; Radix Angelicae Sinensis 14-18 part; Lepidogrammitis drymoglossoides (Bak.) Ching 11-16 part; Folium et Caulis Indigoferae Tinctoriae 8-14 part; Spend very sweet 10-14 part in vain; Herba Portulacae 9-12 part.
2. externally dressing according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Herba Taraxaci 13-15 part; Radix Ampelopsis 9-11 part; Herba Crotalariae Ferrugineae 10-12 part; Rhizoma Tupistrae Wattii 12-14 part; Radix Bupleuri 14-16 part; Herba Erigerontis Annui 11-13 part; Radix Stephaniae Cepharanthae 9-11 part; Folium Hibisci Rosae-Sinensis 11-12 part; Radix Angelicae Sinensis 15-17 part; Lepidogrammitis drymoglossoides (Bak.) Ching 12-15 part; Folium et Caulis Indigoferae Tinctoriae 10-12 part; Spend very sweet 11-13 part in vain; Herba Portulacae 10-11 part.
3. externally dressing according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Herba Taraxaci 14 parts; Radix Ampelopsis 10 parts; Herba Crotalariae Ferrugineae 11 parts; Rhizoma Tupistrae Wattii 13 parts; Radix Bupleuri 15 parts; Herba Erigerontis Annui 12 parts; Radix Stephaniae Cepharanthae 10 parts; Folium Hibisci Rosae-Sinensis 11.5 parts; Radix Angelicae Sinensis 16 parts; Lepidogrammitis drymoglossoides (Bak.) Ching 13 parts; Folium et Caulis Indigoferae Tinctoriae 11 parts; Spend very sweet 12 parts in vain; Herba Portulacae 10.5 parts.
4., according to the preparation method of the arbitrary described externally dressing of claim 1-3, it is characterized in that, step is as follows:
(1) Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae are smashed, be placed in crock, add white vinegar, stir evenly, sealing, put shady and cool place 10-15 days, dry, pulverize, cross 110-130 mesh sieve;
(2) fresh Herba Portulacae is smashed to pieces, be squeezed into juice;
(3) by Herba Taraxaci, Lepidogrammitis drymoglossoides (Bak.) Ching with spend very sweet oven dry in vain, grind as smalls, cross 100-140 mesh sieve;
(4) by Radix Bupleuri and Chinese angelica slicing, be placed in marmite, decoct with water 40-50 minute, add Herba Crotalariae Ferrugineae, Herba Erigerontis Annui, Folium Hibisci Rosae-Sinensis and Folium et Caulis Indigoferae Tinctoriae, continue decoction twice, each decoction 30-40 minute, merging filtrate, being condensed into relative density is 1.10-1.20(25 DEG C) thick paste;
(5) join in step (4) gained thick paste by step (2) gains, mix homogeneously, add step (1) and step (3) gained powder, mixing, makes externally dressing.
5. preparation method according to claim 4, is characterized in that: the consumption of the preferred white vinegar of step (1) is the 40%-50% of Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae gross mass, the consumption being more preferably white vinegar be Radix Ampelopsis, Rhizoma Tupistrae Wattii and Radix Stephaniae Cepharanthae gross mass 45%.
6. preparation method according to claim 4, is characterized in that: step (1) is preferred crosses 116-124 mesh sieve, is more preferably 120 mesh sieves.
7. preparation method according to claim 4, is characterized in that: step (3) is preferred crosses 110-130 mesh sieve, is more preferably 120 mesh sieves.
8. preparation method according to claim 4, is characterized in that: step (4) preferably decocts with water 43-47 minute, is more preferably and decocts with water 45 minutes.
9. preparation method according to claim 4, is characterized in that: step (4) is preferably each decocts 33-37 minute, is more preferably each decoction 35 minutes.
10. preparation method according to claim 4, is characterized in that: it is 1.13-1.17(25 DEG C that step (4) is preferably condensed into relative density) thick paste, being more preferably and being condensed into relative density is 1.15(25 DEG C) thick paste.
CN201510239317.5A 2015-05-13 2015-05-13 Externally applied preparation for treating lymphnoditis and preparation method thereof Pending CN104815127A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102836227A (en) * 2011-06-22 2012-12-26 惠振明 Traditional Chinese medicine preparations used for treating lymphadenitis
CN102920867A (en) * 2011-08-11 2013-02-13 张仲辉 Traditional Chinese medicinal formula for treating acute lymphnoditis caused by accumulated toxic heat hepatic veins
CN103432455A (en) * 2013-08-22 2013-12-11 刘长河 Preparation method of traditional Chinese medicine for treating heat toxin-type acute cervical lymphnoditis

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Publication number Priority date Publication date Assignee Title
CN102836227A (en) * 2011-06-22 2012-12-26 惠振明 Traditional Chinese medicine preparations used for treating lymphadenitis
CN102920867A (en) * 2011-08-11 2013-02-13 张仲辉 Traditional Chinese medicinal formula for treating acute lymphnoditis caused by accumulated toxic heat hepatic veins
CN103432455A (en) * 2013-08-22 2013-12-11 刘长河 Preparation method of traditional Chinese medicine for treating heat toxin-type acute cervical lymphnoditis

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