CN104815004A - Ointment for treating alopecia areata and application thereof - Google Patents

Ointment for treating alopecia areata and application thereof Download PDF

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Publication number
CN104815004A
CN104815004A CN201510275644.6A CN201510275644A CN104815004A CN 104815004 A CN104815004 A CN 104815004A CN 201510275644 A CN201510275644 A CN 201510275644A CN 104815004 A CN104815004 A CN 104815004A
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parts
ointment
alopecia areata
treat
herba
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CN201510275644.6A
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徐艳
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Individual
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Abstract

The invention belongs to the field of traditional Chinese medicine preparations, and in particular discloses an ointment for treating alopecia areata. The ointment is extracted and prepared from the following traditional Chinese medicines in parts by weight: 10-18 parts of zehneria, 14-16 parts of akebia fruit, 12-14 parts of leaf of common aeschynomene, 8-12 parts of herb of sessile alternanthera, 15-20 parts of leaf and twig of kazinoki papermulberry and 12-16 parts of herb of wight parnassia. The ointment disclosed by the invention has a good treatment effect on alopecia areata.

Description

A kind of ointment and application thereof for the treatment of alopecia areata
Technical field
The present invention relates to field of traditional Chinese, be specifically related to a kind of ointment and application thereof for the treatment of alopecia areata.
Background technology
Alopecia areata is the patchy alopecia trichopathy of a kind of limitation suddenly occurred, and product effect is all not so good in the market, is therefore badly in need of a kind of Chinese medicine for the treatment of alopecia areata.
Summary of the invention
Goal of the invention: the object of the present invention is to provide a kind of ointment and application thereof for the treatment of alopecia areata.
Technical scheme:
Treat an ointment for alopecia areata, be prepared from by the Chinese medicine extraction of following weight portion: horse friendship youngster 10-18 part, August explode 14-16 part, Folium Aeschynomenes indicae 12-14 part, Herba clinopodii confinis dish 8-12 part, paddy skin tree 15-20 part, Herba Parnassiae Wightianae 12-16 part.
The ointment of described treatment alopecia areata, is prepared from by the Chinese medicine extraction of following weight portion: horse hands over youngster 14 parts, fried 15 parts of August, Folium Aeschynomenes indicae 13 parts, Herba clinopodii confinis dish 10 parts, paddy skin to set 18 parts, Herba Parnassiae Wightianae 14 parts.
The ointment of described treatment alopecia areata, preparation method is: above Six-element, decocts with water 2 times, add the soak by water 2 hours of medical material weight 10 times amount, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2 at every turn, extractum, get 10 parts, vaseline, lanoline 2 parts, liquid Paraffin 2 parts be mixed with substrate, be heated to 150 DEG C, well is incubated 1.5 hours, filter, in time being chilled to about 60 DEG C, add above-mentioned extractum, mixing, obtains faint yellow to yellow ointment.
The application of ointment in preparation alopecia areata medicine of described treatment alopecia areata.
Horse hands over youngster, and Classification system Melothria ndica Lour.Zehneria indica (Lour.) C.Y., Herb is used as medicine, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For laryngopharynx swelling and pain, conjunctivitis; Sore swollen toxin is controlled in external, tuberculous lymphadenitis, orchitis, skin eczema.
August explodes, Classification system Holboellia fargesii Reaub., is fallen leaves woody climber, high 10m.Bark has obvious point-like protruding, the brown or brown of branch; Minor matters place has place to deposit perula, and bottom person is slightly with wooden, top papery, all without hair.Trifoliolate leaf, cluster in branch end, petiole is thin and delicate, long 6 ~ 8cm, vanelets oval, width egg shape or long oval etc., length and width change greatly, the blunt circle of tip, central nick or the short point of tool, basal circular or wide wedge shape, sometimes in micro-heart, full edge or in wavy, lateral vein is usual 5 ~ 6 right.Flower unisexuality, hermaphroditism, aubergine, raceme axil is raw, and be about 8cm, male flower is less, and most, and be born in inflorescence top, tool squamella, perianth 3, stamen 6, filigree is flat; Female flower 1 ~ 3, and is born in inflorescence bottom, bract wire lanceolar, perianth 3, stamen 6, and filigree is flat; Female flower 1 ~ 3, and is born in inflorescence bottom, bract wire lanceolar, perianth 3, and wide ellipse is blunt nosed, tool staminodium 6, carpel 3 ~ 12, and from life, stigma head, ovary cylindrical shape or slightly bending, upper Room 1, parietal placenta, ovule is most.Follicle radish sarcocarp matter, oblong, aubergine time ripe, ftractures along ventral suture.Seed sealene triangle, slightly flat, rufous, it is fine and closely woven and glossy that tool indulges wrinkle, and be embedded in canescence fruit flesh, hilum is slightly partial to, the spongy strophiole of its other visible white.4 ~ May of florescence, really 8 ~ October of phase.Soothing the liver, the kidney invigorating, pain relieving, diuresis, parasite killing.Cure mainly: stomachache, colic, painful and swollen testis, lumbago, seminal emission, menoxenia, leucorrhea, uterine prolapse.For gastral cavity side of body distending pain, amenorrhea dysmenorrhea, dysuria, snake bite and insect sting.
Folium Aeschynomenes indicae is the leaf of leguminous plant Herba Aeschynonenes Indicae, can treat carbuncle, the diseases such as wound hemorrhage.
Herba clinopodii confinis dish Latin is called Clinopodium confine (Hance) O.Ktze., Labiatae Clinopodium plant.With all herbal medicine.Spring and summer is gathered, and cleans, using fresh herb or dry.Heat-clearing and toxic substances removing, hemostasis.Carbuncle furuncle is controlled in external, mastitis, innominate toxic swelling, knife injury.Urticaria, allergic dermatitis.
Paddy skin tree belongs to moraceae plants little Broussonetia papyrifera Broussonetia kazinoki Sieb.et Zucc. for structure, is used as medicine with root, root bark, bark and leaf.The present invention is used as medicine with root.Root, root bark: eliminating stasis to stop pain.For traumatic injury, lumbago.Leaf, bark juice: removing toxic substances, parasite killing.Neurodermatitis is controlled in external, stubborn dermatitis.
Herba Parnassiae Wightianae is that brave otology Parnassia plant clavus Herba parnassiae Parnassia wightiana Wall. is with all herbal medicine.Xia Qiu gathers herb, cleans and dries.Clearing away lung-heat to relieve cough, diuretic damp eliminating.For chronic cough spitting of blood, malaria, renal calculus, cholelithiasis, leucorrhea, traumatic injury; Damp and hot sore is controlled in external.
Beneficial effect: in the present invention, horse hands over youngster's heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, and August explodes soothing the liver, the kidney invigorating, pain relieving, diuresis, parasite killing, both are monarch drug altogether, Folium Aeschynomenes indicae, Herba clinopodii confinis dish heat-clearing and toxic substances removing are ministerial drug, and Gu Pishu, Herba Parnassiae Wightianae eliminating stasis to stop pain are adjuvant, and alopecia areata is treated by full side, respond well.
Detailed description of the invention
Embodiment 1: get that horse hands over youngster 10g, August explodes 16g, Folium Aeschynomenes indicae 12g, Herba clinopodii confinis dish 12g, paddy skin tree 15g, Herba Parnassiae Wightianae 16g, above Six-element, decoct with water 2 times, add the soak by water 2 hours of medical material weight 10 times amount at every turn, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2, extractum, get vaseline 10g, lanoline 2g, liquid Paraffin 2g be mixed with substrate, be heated to 150 DEG C, well is incubated 1.5 hours, filter, in time being chilled to about 60 DEG C, add above-mentioned extractum, mixing, obtains faint yellow to yellow ointment.
Embodiment 2: get that horse hands over youngster 14g, August explodes 15g, Folium Aeschynomenes indicae 13g, Herba clinopodii confinis dish 10g, paddy skin tree 18g, Herba Parnassiae Wightianae 14g, above Six-element, decoct with water 2 times, add the soak by water 2 hours of medical material weight 10 times amount at every turn, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2, extractum, get vaseline 10g, lanoline 2g, liquid Paraffin 2g be mixed with substrate, be heated to 150 DEG C, well is incubated 1.5 hours, filter, in time being chilled to about 60 DEG C, add above-mentioned extractum, mixing, obtains faint yellow to yellow ointment.
Embodiment 3: get that horse hands over youngster 18g, August explodes 14g, Folium Aeschynomenes indicae 14g, Herba clinopodii confinis dish 8g, paddy skin tree 20g, Herba Parnassiae Wightianae 12g, above Six-element, decoct with water 2 times, add the soak by water 2 hours of medical material weight 10 times amount at every turn, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2, extractum, get vaseline 10g, lanoline 2g, liquid Paraffin 2g be mixed with substrate, be heated to 150 DEG C, well is incubated 1.5 hours, filter, in time being chilled to about 60 DEG C, add above-mentioned extractum, mixing, obtains faint yellow to yellow ointment.
Embodiment 4: the present invention treats the clinical research of alopecia areata
Clinical medicine: by the ointment of above-mentioned enforcement 2 method preparation treatment alopecia areata, external, 2 times on the one, external, is applied to affected part by ointment.
The routine patient of clinical observation 50, man 26 example, female 24 example, age 35-58 year, the course of disease is the shortest 2 months, the longest 1 year, external ointment of the present invention six months.
Diagnostic criteria: 1, can be sent out in any age, common with person between twenty and fifty.2, be everlasting overworked, do not have enough sleep or occur after being subject to direct stimulation.3, onset is unexpected, and patient is many inadvertently finds alopecia, rounded or irregular shape, little of fingernail, and greatly as coin or more greatly, number is not etc.4, skin smooth and bright, NIP, boundary is clear, and follicular orifice is clearly visible, or has very thin bob to exist.5, the hair of alopecia area edge often loosens and easily pulls out, and the hair extracted is upper-wide lower-thin state.6, small number of patients hair all can take off light, is alopecia totalis.Severe patient eyebrow, beard, internal organs hair, pubes also come off completely, and fine hair on birds or animals hair is also tear-away, claim alopecia universalis.7, general no conscious sympton, or have pruritus, also can with dizzy, dizzy, vexed, insomnia, dreaminess etc.8, the course of disease is slow, alopecia spot can long inactivity constant, also can increase the weight of gradually.There is spontaneous recovery to be inclined to, but be easy to go again come off, so that the course of disease sustainable several months or more of a specified duration.When recovering, affected part is newly sent out and is grown, from the beginning of thin and soft, in yellowish or canescence, thicker, hardening, blackening with the passing of time gradually, finally identical with healthy hair.
Efficacy evaluation: 1. clinical recovery: treat alopecia district in later six months and bear new sending out, and new alopecia areata district no longer occurs.2. take a turn for the better: after controlling half a year, 50% alopecia areata district generates new sending out, though You Xin alopecia areata district occurs, scope reduces than before treatment.3. invalid: to treat half a year more than, alopecia district is without kainogenesis length or only have sparse hair, still sees that new alopecia areata district is formed.
Table 1. the present invention treats the observation of curative effect of alopecia areata patient
The present invention is through clinical practice, and treatment alopecia areata has obvious effect, is 92% by finding out that the present invention treats alopecia areata total effective rate in table, and has no adverse reaction in using.

Claims (4)

1. treat an ointment for alopecia areata, it is characterized in that, be prepared from by the Chinese medicine extraction of following weight portion: horse friendship youngster 10-18 part, August explode 14-16 part, Folium Aeschynomenes indicae 12-14 part, Herba clinopodii confinis dish 8-12 part, paddy skin tree 15-20 part, Herba Parnassiae Wightianae 12-16 part.
2. treat the ointment of alopecia areata as claimed in claim 1, it is characterized in that, be prepared from by the Chinese medicine extraction of following weight portion: horse hands over youngster 14 parts, fried 15 parts of August, Folium Aeschynomenes indicae 13 parts, Herba clinopodii confinis dish 10 parts, paddy skin to set 18 parts, Herba Parnassiae Wightianae 14 parts.
3. treat the ointment of alopecia areata as claimed in claim 1, it is characterized in that, preparation method is: above Six-element, decoct with water 2 times, add the soak by water 2 hours of medical material weight 10 times amount, collecting decoction at every turn, when being concentrated into 65 DEG C, relative density is 1.2, obtains extractum, gets 10 parts, vaseline, lanoline 2 parts, liquid Paraffin 2 parts be mixed with substrate, be heated to 150 DEG C, well is incubated 1.5 hours, filters, in time being chilled to about 60 DEG C, add above-mentioned extractum, mixing, obtain faint yellow to yellow ointment.
4. described in, treat the application of ointment in treatment alopecia areata medicine of alopecia areata.
CN201510275644.6A 2015-05-26 2015-05-26 Ointment for treating alopecia areata and application thereof Pending CN104815004A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105147928A (en) * 2015-09-22 2015-12-16 淄博齐鼎立专利信息咨询有限公司 Traditional Chinese medicine ointment treating alopecia areata

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102362873A (en) * 2011-11-28 2012-02-29 卞毓平 Use of Xiaomeng oculentum in preparation of medicines for treating alopecia areata

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102362873A (en) * 2011-11-28 2012-02-29 卞毓平 Use of Xiaomeng oculentum in preparation of medicines for treating alopecia areata

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105147928A (en) * 2015-09-22 2015-12-16 淄博齐鼎立专利信息咨询有限公司 Traditional Chinese medicine ointment treating alopecia areata

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Application publication date: 20150805