CN104814992A - Medicine for treating onychomycosis and manufacturing method thereof - Google Patents

Abstract

The invention discloses medicine for treating onychomycosis and a manufacturing method thereof. The manufacturing method includes that firstly, taking bitter gourd leaves, removing leaf stalks, cleaning, drying, adding cold water, taking out after boiling, mashing, pressing, filtering and cooling for latter use; secondly, taking henna leaves, removing leaf stalks, cleaning, drying, adding cold water, taking out after boiling, mashing, pressing, filtering and cooling for latter use; thirdly, mixing the two kinds of filtered medicine, heating and stirring to form mixed medicine, and cooling for latter use; fourthly, adding glacial acetic acid to the cooled mixed medicine to regulate the PH to 3 to 4; finally, precipitating and filtering the prepared medicine, and filling to obtain a finished product. The medicine for treating onychomycosis is featured with short treatment period, easiness in treatment operation, obvious curative effect and no relapse, and a patient does not to have an operation so that the patient is not painful.

Description

A kind of medicine for the treatment of tinea unguium and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of tinea unguium.

Background technology

Tinea unguium is one is the class disease referring to (toe) first by dermatophytes infringement and cause.Show as finger (toe) nail discoloration (the greyish white or dirty Huang of color, severe patient becomes taupe) more, deck tarnishes, thicken, surface is uneven, dunghill is piled up or deck is destroyed, disappearance.Excessive keratinization, refer to that (toe) first easily ruptures, first matter is crisp becomes a large amount of chips of accumulation, and severe patient deck departs from base portion completely.In tinea unguium, fungus can produce about 150 kinds of different toxin, and wherein many toxin can be carcinogenic and toxicity is extremely strong, and drugs potassium cyanide as huge in the toxicity ratio of aflatoxin B1 in mycete is poison tens times also, is strong carcinogen.It is attractive in appearance that tinea unguium affects trick, health risk, infringement self-image; Mental pressure is produced to patient; As: introversive, be reluctant to shake hands with people, be reluctant to transmit article.Tinea unguium easily has infectiousness, and often and family and friends, kith and kin together, infect Chang Yin and change footwear, trick contact and share the articles for daily use, very easily cause household's fungal infection, formed tinea manus and pedis, tinea corporis, tinea cruris, etc. severe skin disease.Tinea unguium not only infects, endanger skin histology, invades human internal organs too, even causes death.

The method of present clinical treatment tinea unguium generally has following three classes:

1, first is pulled out in operation: under local anesthesia, trouble first pulled out.This method wound surface is hemorrhage, easily causes infection.Post operation generally can feel comparatively pain, general because the fingernail probability that makes new advances of regrowing after extracting is very small, and because the reason of operation and afterwards nurse the easy re-infection recurrence of reason.The patient of heart disease, hypertension, diabetes etc., unsuitable operative treatment.

2, endo-medicine: take merely antifungal drug as griseofulvin, fluconazol, health azoles (itraconazole) etc., have certain curative effect, and convenient.But because this kind of medicine must reach parasitic deck place competence exertion antibacterial action, and dissolubility in water is low waits a moment, and Absorption And Metabolism is very fast again, so dosage is large, administration time is long.In addition, oral medicine all has side effect, and easily recurs after drug withdrawal, therefore should not as the conventional treatment drug of tinea unguium.

3, Topical therapy: Topical therapy generally should be selected to treat tinea unguium, different according to medicine, mainly contain immersion, local application and package and cut methods such as controlling.But these method therapeutic processes are loaded down with trivial details, high cost, be kind of a burden to consumer; And the fungus in tinea unguium is eliminated not thorough, cause often because therapeutic process is long and the long-term maintenance of consumer to this product is loaded down with trivial details, self abandons, and makes disease first can not obtain the chance of healing.

Summary of the invention

In order to overcome existing clinical treatment tinea unguium method above shortcomings, object of the present invention is improved mainly for some above shortcomings and enforcement treatment operation, there is provided a kind for the treatment of cycle short, treat simple to operate, patient is without the need to operation, not painful, therapeutic effect is obvious, the treatment tinea unguium medicine do not recurred and manufacture method.

In order to achieve the above object, the present invention is achieved through the following technical solutions: a kind of medicine for the treatment of tinea unguium, is made up of following percentage by weight raw material; Folium Momordicae Charantiae 1-8, Folium Lawsoniae 1-8, glacial acetic acid 1-90.

A kind of production method of medicament for the treatment of tinea unguium described in such scheme::

A) get Fructus Momordicae charantiae leaf and remove petiole, clean and dry, add cold water and boil and continue to take out after 5-8 minute to 100 degree, mash, squeeze, with 200 order drainage screen filterings, cool for subsequent use;

B) fetching first Paphio-pedilum micranthum Tang et Wang removes petiole, cleans and dries, and adds cold water and boils and continue to take out after 5-8 minute to 100 degree, mash, squeeze, with 200 order drainage screen filterings, cool for subsequent use;

C) by above two kinds of filtered drug mixing, heat, stir, boil to 60-65 degree, constant temperature 20 minutes, makes hybrid medicine, cools for subsequent use;

D) hybrid medicine after cooling is added glacial acetic acid and be adjusted to PH3 ~ 4;

E) by the drug precipitation 24 hours after configuration, with 300 order drainage screen filterings, fill is finished product.

The present invention is by above formula combination and strict technology, and the various fungus of curing the disease of a kind of applicable treatment of making causes effective liquid medicine of tinea unguium, uses simple, shortens treatment cycle, improve therapeutic effect.

Folium Momordicae Charantiae and Folium Lawsoniae and glacial acetic acid is have employed in formula of the present invention;

Folium Momordicae Charantiae: containing number of chemical composition, as Charantin, have heat-clearing toxin-expelling functions, to Antifungi, streptococcus living environment, plays and eliminates fungus effect.

Flos Impatientis: containing lawsone, there is heat clearing away and the effect for the treatment of wound, the effect of protection skin is played to tinea unguium treatments period.

Glacial acetic acid: low concentration, permeability are strong, destroys fungus living environment, plays and eliminates fungus effect.

In Folium Momordicae Charantiae and Folium Lawsoniae containing natural can effect of Antifungi, add the permeability of glacial acetic acid, by strict preparation and practical application, the efficacy of a drug is gone directly focus, the growth of elimination and Antifungi, make new first have resistance fungus tinea unguium is extruded always, reach the object shortening treatment cycle and improve therapeutic effect.

Detailed description of the invention

Embodiment 1:

A) get 200 grams, Fructus Momordicae charantiae leaf and remove petiole, clean and dry, add 500 grams, cold water and boil and continue to take out after 6 minutes to 100 degree, mash, squeeze, with 200 order drainage screen filterings, cool for subsequent use;

B) fetching first Paphio-pedilum micranthum Tang et Wang 200 grams removes petiole, cleans and dries, and adds 500 grams, cold water and boils and continue to take out after 6 minutes to 100 degree, mash, squeeze, with 200 order drainage screen filterings, cool for subsequent use;

C) by above two kinds of filtered drug mixing, heat, stir, boil to 60 degree, constant temperature 20 minutes, makes hybrid medicine, cools for subsequent use;

D) hybrid medicine after cooling is added glacial acetic acid, be adjusted to PH3;

E) by the drug precipitation 24 hours after configuration, with 300 order drainage screen filterings, fill is finished product.

Embodiment 2:

C) get 500 grams, Fructus Momordicae charantiae leaf and remove petiole, clean and dry, add 1250 grams, cold water and boil and continue to take out after 7 minutes to 100 degree, mash, squeeze, with 200 order drainage screen filterings, cool for subsequent use;

D) fetching first Paphio-pedilum micranthum Tang et Wang 500 grams removes petiole, cleans and dries, and adds 1250 grams, cold water and boils and continue to take out after 7 minutes to 100 degree, mash, squeeze, with 200 order drainage screen filterings, cool for subsequent use;

C) by above two kinds of filtered drug mixing, heat, stir, boil to 65 degree, constant temperature 20 minutes, makes hybrid medicine, cools for subsequent use;

D) hybrid medicine after cooling is added glacial acetic acid, be adjusted to PH4;

E) by the drug precipitation 24 hours after configuration, with 300 order drainage screen filterings, fill is finished product.

This product is my invention, and I infects tinea unguium by the left hand third finger, does not take notice of for the first time, thinks that bad fingernail will come off naturally along with new fingernail grows.As time goes on, find that new fingernail is longer, bad fingernail does not only come off, but every new fingernail grows to disease fingernail position, and will to become disease fingernail the same; And start to occur extending inwards.I am worried seeks medical advice and medicine everywhere, eat and be coated with many medicines, until the sick first of the one-year age not only left hand third finger is more and more serious, also there is the symptom of tinea unguium in the right hand, some knowledge of the tinea unguium that now begins one's study in person and reason, after continuous trial uses this formula, tinea unguium has come off, and has grown brand-new fingernail after 3 months.My fingernail is always healthy until now.Found that many people have the situation of this tinea unguium as me, this medicine is just promoted the use of in them by I simultaneously, in the 30-40 people through using, substantially all fully recovers.

Above a kind of medicine for the treatment of tinea unguium provided by the present invention is described in detail, apply instantiation herein to set forth pharmacology of the present invention and embodiment, the explanation of above embodiment just understands the technical program and core concept thereof for helping; Meanwhile, for one of ordinary skill in the art, according to summary of the invention, all will change in specific embodiments and applications, in sum, this description should not be construed as limitation of the present invention.

Claims (2)

1. treat a medicine for tinea unguium, it is characterized in that being made up of following percentage by weight raw material; Folium Momordicae Charantiae 1-8, Folium Lawsoniae 1-8, glacial acetic acid 1-90.

2. a kind of production method of medicament for the treatment of tinea unguium according to claim 1, is characterized in that:

A) get Fructus Momordicae charantiae leaf and remove petiole, clean and dry, add cold water and boil and continue to take out after 5-8 minute to 100 degree, mash, squeeze, with 200 order drainage screen filterings, cool for subsequent use;

B) fetching first Paphio-pedilum micranthum Tang et Wang removes petiole, cleans and dries, and adds cold water and boils and continue to take out after 5-8 minute to 100 degree, mash, squeeze, with 200 order drainage screen filterings, cool for subsequent use;

C) by above two kinds of filtered drug mixing, heat, stir, boil to 60-65 degree, constant temperature 20 minutes, makes hybrid medicine, cools for subsequent use;

D) hybrid medicine after cooling is added glacial acetic acid and be adjusted to PH3-4;

E) by the drug precipitation 24 hours after configuration, with 300 order drainage screen filterings, fill is finished product.