CN104814721A - Triangular wave frequency coding high spectral imaging measurement system applied to mammary gland - Google Patents

Abstract

The invention discloses a triangular wave frequency coding high spectral imaging measurement system applied to a mammary gland. A group of monochromatic light sources are distributed on one side of a mammary tissue sample, cameras are distributed on the other side of the mammary tissue sample, all the monochromatic light sources in the group of monochromatic light sources are densely arranged on one hemispherical surface and collected into a beam of light by a lens to form a light source, a light source receiving device comprises the cameras, triangular waves with different frequencies and a two-time ratio relationship respectively drive all the monochromatic light sources in the group of monochromatic light sources, each pixel point in an image received by the cameras is a monochromatic light combination with each monochromatic light source penetrating the mammary gland, and a computer separates the monochromatic light combination to obtain the contribution of each monochromatic light source in the monochromatic light combination, so that transmission high spectral imaging for the mammary gland is realized. The system realizes high-speed and high-information mammary gland transmission high spectral imaging high-precision measurement, has the advantages of low cost, convenience on application and the like, and is suitable for regular family self-inspection.

Description

Be applied to the high-spectrum imaging measurement system of the triangular wave frequency coding of mammary gland

Technical field

The present invention relates to imaging measurement system field, particularly relate to a kind of high-spectrum imaging measurement system being applied to the triangular wave frequency coding of mammary gland.

Background technology

By light, imaging is carried out to interior of articles in prior art, particularly imaging is carried out to inside of human body, there is the outstanding advantages that harmless noinvasive is radiationless, but not yet there is the mammary gland transmission imaging light measurement system that can enter family's use so far for regular tumor self-inspection, its reason is that the cost of existing breast imaging measuring system is high, computing is complicated, limited precision, cannot meet the breast self-exams needs in practical application.

Summary of the invention

The invention provides a kind of high-spectrum imaging measurement system being applied to the triangular wave frequency coding of mammary gland, present invention achieves the high-acruracy survey of high speed, the mammary gland transillumination imaging of information greatly, meet the needs in practical application, described below:

Be applied to a high-spectrum imaging measurement system for the triangular wave frequency coding of mammary gland, described imaging measurement system comprises: one group of monochromater, photographic head, and the computer external with photographic head; One group of monochromater is distributed in the side of mammary gland tissue sample, and photographic head is distributed in the opposite side of mammary gland tissue sample;

Wherein, each monochromater dense arrangement in one group of monochromater, on a set hemisphere face, adopts lens to pool light beam, forms light source; Photographic head forms light source receiver part;

Adopt different frequency and become the triangular wave of 2 times of ratio to drive each monochromater in one group of monochromater respectively, in the image that photographic head receives, to be each monochromater combine through the monochromatic light of mammary gland each pixel;

Computer is separated the contribution of each monochromater obtained in monochromatic light combination to monochromatic light combination, realize the transmission high-spectrum imaging to mammary gland accordingly.

Wherein, described monochromater, described photographic head are symmetrical arranged on described mammary gland tissue sample two sides.

Wherein, described monochromater is laser diode.

Another embodiment, described monochromater is monochrome photodiode.

Another embodiment, described photographic head is mobile phone camera.

The beneficial effect of technical scheme provided by the invention is: the present invention adopts different frequency and becomes the triangular wave of 2 times of ratio to drive monochromater, the contribution that separation can obtain each monochromater in monochromatic light combination is carried out to the photosignal that photographic head detects, and then the imaging realized mammary gland tissue sample, present invention achieves the high-acruracy survey of high speed, greatly the linear array imaging light of information, and the present invention has the advantages such as cost is low, application is convenient, is suitable for family's self-inspection.

Accompanying drawing explanation

Fig. 1 is a kind of structural representation being applied to the high-spectrum imaging measurement system of the triangular wave frequency coding of mammary gland;

Fig. 2 is monochromater provided by the invention, mammary gland tissue sample and photographic head relative position schematic diagram;

Fig. 3 is the schematic diagram of triangular wave.

In accompanying drawing, the list of parts representated by each label is as follows:

1: one group of monochromater; 2: lens;

3: mammary gland tissue sample; 4: photographic head.

Detailed description of the invention

For making the object, technical solutions and advantages of the present invention clearly, below embodiment of the present invention is described further in detail.

Embodiment 1

A kind of high-spectrum imaging measurement system being applied to the triangular wave frequency coding of mammary gland, see Fig. 1 and Fig. 2, imaging measurement system comprises: one group of n monochromater 1 (represents with LD, the wavelength of monochromater is between 600 ~ 1200nm, this wave band is " optical window ", and penetration depth is deep) and a photographic head 4, (wherein, the sensitivity of concrete value and mammary gland tissue sample 3 pairs of different wave lengths of n is relevant, and the embodiment of the present invention does not limit this); One group of monochromater 1 is distributed in the side of mammary gland tissue sample 3, and a photographic head 4 is distributed in the opposite side of mammary gland tissue sample 3;

Wherein, each monochromater LD in one group of monochromater 1 ₁lD _ndense arrangement, on a set hemisphere face, adopts lens 2 to pool light beam, forms array light source; Photographic head 4 forms multi wave length illuminating source receiving device, and photographic head 4 is CMOS or CCD, and existing photographic head 4 can gather the light of near infrared band.This imaging measurement system also comprises the computer (not shown) external with photographic head 4.

See Fig. 3, adopt different frequency and become the triangular wave of 2 times of ratio to drive each monochromater LD in one group of monochromater 1 respectively _i, photographic head 4 gathers, and in the image collected, each pixel is each monochromater LD _ithrough the monochromatic light combination I of mammary gland tissue sample 3 _ij; Computer combines I to monochromatic light _ijcarry out separation and can obtain monochromatic light combination I _ijin each monochromater LD _icontribution, form the transmission image under each wavelength.Different according to the optical characteristics of normal structure, tumor tissues etc. in mammary gland tissue under each wavelength, carry out the transillumination imaging measurement of mammary gland, realize the earlier detection of tumor.

Wherein, computer combines I to monochromatic light _ijcarry out separation and can obtain monochromatic light combination I _ijin each monochromater LD _ithe step of contribution be specially:

1) LD to drive monochromater is supposed _jhighest frequency f _max4M speed sampling f is carried out to photosignal _s=4M × f _max, obtain sampled signal x (m), wherein M be more than or equal to 1 positive integer;

$x\left(m\right)=\underset{i=0}{\overset{M-1}{\mathrm{\Σ}}}x(4\mathrm{lm}-i),l=\mathrm{0,1,2},......---\left(1\right)$

2) computer will add up to the sampled signal in the positive and negative half period in each triangular wave cycle corresponding to each wavelength respectively, and accumulation result carries out asking difference operation;

That is, obtain cumulative sum by cumulative for the sampled value of the positive half period of each triangular wave in certain hour (an integer triangular wave cycle), the sampled value of the negative half period of each triangular wave is cumulative obtains cumulative sum, and these two cumulative sums are subtracted each other.

3) difference of each wavelength above-mentioned is carried out k cycle or an integral multiple k periodic accumulation, wherein:

$k=\frac{a\frac{1}{f_{\min }}}{\frac{1}{f_n}}---\left(2\right)$

In formula: f _minfor the low-limit frequency in excitation triangular wave; A is preset constant, value be more than or equal to 1 positive integer, a/f _minfor the cycle of lower sampling; f _nfor the triangular wave driving frequency of handled wavelength.

To amplitude be x be sampled value, if uniform sampling N (>>1) puts and is averaged within the regular hour, the meansigma methods obtained is

$\stackrel{\‾}{x}=\frac{1}{N}\underset{i=1}{\overset{N}{\mathrm{\Σ}}}\left[x_i\right]=\frac{1}{N}N\left(\right[x]+{\mathrm{\Δx}}_i)=\left[x\right]+{\mathrm{\Δx}}_i---\left(3\right)$

Wherein, [x] is that analog-digital converter quantizes x, is also the positive integer that round off rounding obtains.X _ithe amplitude of i-th, [x _i] be that analog-digital converter is to x _iquantizing, is also the positive integer that round off rounding obtains.

(3) formula shows, the signal sampling one being compared to " totally " is repeatedly averaged, and can not improve its precision, and the error of the meansigma methods obtained is identical with the error of unitary sampling, is Δ x _i.

If to amplitude be x be sampled sawtooth waveforms, within the regular hour, uniform sampling N (>>1) puts and is averaged equally, and the meansigma methods obtained is

$\stackrel{\‾}{x}=\frac{1}{N}\underset{i=1}{\overset{N}{\mathrm{\Σ}}}\left[x_i\right]=\frac{1}{N}\underset{i=1}{\overset{N}{\mathrm{\Σ}}}[m_i+{\mathrm{\Δx}}_i]---\left(4\right)$

Wherein, x _i=m _i+ Δ x _i, m _i=[x _i].Also be m _ithat rounding obtains positive integer, and Δ x _iit is " at random " error of losing after being rounded.

(4) formula can utilize arithmetic series sum formula to obtain further:

$\begin{array}{c}\stackrel{\‾}{x}=\frac{1}{N}\underset{i=1}{\overset{N}{\mathrm{\Σ}}}{m}_i+\frac{1}{N}\underset{i=1}{\overset{N}{\mathrm{\Σ}}}{\mathrm{\Δx}}_i=\frac{1}{N}\frac{1}{2}(0+[x\left]\right)N+\frac{1}{N}\underset{i=1}{\overset{N}{\mathrm{\Σ}}}{\mathrm{\Δx}}_i\\ =\frac{1}{2}\left[x\right]+\frac{1}{N}\underset{i=1}{\overset{N}{\mathrm{\Σ}}}{\mathrm{\Δx}}_i\end{array}---\left(5\right)$

(5) the last item in formula is the value after quantizing, although less than the result of (3) formula half, according to error theory, the precision of data does not change because being multiplied by a fixing non-zero constant.But be the random number of zero-mean in one next, compare will reduce in (3) formula doubly, therefore, the effect of the precision that can be improved equally after over-sampling is carried out to sawtooth waveforms or triangular wave pumping signal, and do not need another external high-frequency disturbing signal.

The embodiment of the present invention is to the model of each device except doing specified otherwise, and the model of other devices does not limit, as long as can complete the device of above-mentioned functions.

Embodiment 2

Be applied to a high-spectrum imaging measurement system for the triangular wave frequency coding of mammary gland, see Fig. 1 and Fig. 2, this embodiment is using laser diode as monochromater LD ₁lD _nfor example is described.

Adopt different frequency and become the triangular wave of 2 times of ratio to drive each laser diode LD in one group of monochromater 1 respectively _i, in photographic head 4, each pixel receives each laser diode LD _ithrough the monochromatic light combination I of mammary gland tissue sample 3 _ij; Computer combines I to monochromatic light _ijcarry out separation and can obtain monochromatic light combination I _ijin each laser diode LD _icontribution, the imaging of transmission high-spectrum can be carried out to mammary gland tissue sample 3 accordingly.

Computer disposal step in the present embodiment is all identical with embodiment 1, and the present embodiment does not repeat them here.

The embodiment of the present invention is to the model of each device except doing specified otherwise, and the model of other devices does not limit, as long as can complete the device of above-mentioned functions.

Embodiment 3

Be applied to a high-spectrum imaging measurement system for the triangular wave frequency coding of mammary gland, see Fig. 1 and Fig. 2, this embodiment is using monochrome photodiode as monochromater LD ₁lD _nfor example is described.

Adopt different frequency and become the triangular wave of 2 times of ratio to drive each monochrome photodiode LD in one group of monochromater 1 respectively _i, in photographic head 4, each pixel receives each monochrome photodiode LD _ithrough the monochromatic light combination I of mammary gland tissue sample 3 _ij; Computer combines I to monochromatic light _ijcarry out separation and can obtain monochromatic light combination I _ijin each monochrome photodiode LD _icontribution, the imaging of transmission high-spectrum can be carried out to mammary gland tissue sample 3 accordingly.

Computer disposal step in the present embodiment is all identical with embodiment 1, and the present embodiment does not repeat them here.

The embodiment of the present invention is to the model of each device except doing specified otherwise, and the model of other devices does not limit, as long as can complete the device of above-mentioned functions.

Embodiment 4

Be applied to a high-spectrum imaging measurement system for the triangular wave frequency coding of mammary gland, see Fig. 1 and Fig. 2, this embodiment is using laser diode as monochromater LD ₁lD _n, mobile phone camera is that example is described as photographic head.

Adopt different frequency and become the triangular wave of 2 times of ratio to drive each laser diode LD in one group of monochromater 1 respectively _i, in cell-phone camera 4, each pixel receives each laser diode LD _ithrough the monochromatic light combination I of mammary gland tissue sample 3 _ij; Computer combines I to monochromatic light _ijcarry out separation and can obtain monochromatic light combination I _ijin each laser diode LD _icontribution, the imaging of transmission high-spectrum can be carried out to mammary gland tissue sample 3 accordingly.

Computer disposal step in the present embodiment is all identical with embodiment 1, and the present embodiment does not repeat them here.

The embodiment of the present invention is to the model of each device except doing specified otherwise, and the model of other devices does not limit, as long as can complete the device of above-mentioned functions.

Embodiment 5

Be applied to a high-spectrum imaging measurement system for the triangular wave frequency coding of mammary gland, see Fig. 1 and Fig. 2, this embodiment is using monochrome photodiode as monochromater LD ₁lD _n, mobile phone camera is that example is described as photographic head.

Adopt different frequency and become the triangular wave of 2 times of ratio to drive each monochrome photodiode LD in one group of monochromater 1 respectively _i, in cell-phone camera 4, each pixel receives each monochrome photodiode LD _ithrough the monochromatic light combination I of mammary gland tissue sample 3 _ij; Computer combines I to monochromatic light _ijcarry out separation and can obtain monochromatic light combination I _ijin each laser diode LD _icontribution, the imaging of transmission high-spectrum can be carried out to mammary gland tissue sample 3 accordingly.

Computer disposal step in the present embodiment is all identical with embodiment 1, and the present embodiment does not repeat them here.

The embodiment of the present invention is to the model of each device except doing specified otherwise, and the model of other devices does not limit, as long as can complete the device of above-mentioned functions.

It will be appreciated by those skilled in the art that accompanying drawing is the schematic diagram of a preferred embodiment, the invention described above embodiment sequence number, just to describing, does not represent the quality of embodiment.

The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (5)

1. be applied to a high-spectrum imaging measurement system for the triangular wave frequency coding of mammary gland, described imaging measurement system comprises: one group of monochromater, photographic head, and the computer external with photographic head; It is characterized in that, one group of monochromater is distributed in the side of mammary gland tissue sample, and photographic head is distributed in the opposite side of mammary gland tissue sample;

Wherein, each monochromater dense arrangement in one group of monochromater, on a set hemisphere face, adopts lens to pool light beam, forms light source; Photographic head forms light source receiver part;

Adopt different frequency and become the triangular wave of 2 times of ratio to drive each monochromater in one group of monochromater respectively, in the image that photographic head receives, to be each monochromater combine through the monochromatic light of mammary gland each pixel;

Computer is separated the contribution of each monochromater obtained in monochromatic light combination to monochromatic light combination, realize the transmission high-spectrum imaging to mammary gland accordingly.

2. a kind of high-spectrum imaging measurement system being applied to the triangular wave frequency coding of mammary gland according to claim 1, it is characterized in that, described monochromater, described photographic head are symmetrical arranged on described mammary gland tissue sample two sides.

3. a kind of high-spectrum imaging measurement system being applied to the triangular wave frequency coding of mammary gland according to claim 1 and 2, it is characterized in that, described monochromater is laser diode.

4. a kind of high-spectrum imaging measurement system being applied to the triangular wave frequency coding of mammary gland according to claim 1 and 2, it is characterized in that, described monochromater is monochrome photodiode.

5. a kind of high-spectrum imaging measurement system being applied to the triangular wave frequency coding of mammary gland according to claim 1 and 2, it is characterized in that, described photographic head is mobile phone camera.