CN104800808A - Medicine for treating gastric ulcer and preparation method thereof - Google Patents

Abstract

The invention provides a medicine for treating gastric ulcer. The medicine comprises ginger processed pinellia, coptis chinensis, scutellaria baicalensis, rhizoma corydalis processed with rice vinegar, codonopsis pilosula, roasted radix aucklandiae, rhizoma zingiberis, cuttlebone, bulbus fritillariae thunbergii, bran-processed rhizoma atractylodis and liquorice. The medicine provided by the invention is capable of regulating chills and fever and eliminating dampness and complies to the traditional Chinese medicine treating rule for strengthening the body resistance to eliminate pathogenic factors; a harmonization method is mainly taken as a treating method; the flexible application of warming, clearing, eliminating and complementing in eight therapeutic methods is reflected; through a smart composition, the neutralizing curative effect is achieved; the method, formula and prescription of the medicine can fully reflect the integrality and dialectical property of the traditional Chinese medicine treating rule; the prescription is unique; the curative effect is accurate; no obvious toxic side effect exists.

Description

A kind of medicine for the treatment of gastric ulcer and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition, especially a kind of medicine for the treatment of gastric ulcer and preparation method thereof.

Background technology

Gastric ulcer (Gastric ulcer, GU) is that ulcer occurs in gastric mucosa surface, the defect pathological changes of festering that the local organization caused due to a variety of causes is formed because necrosis comes off, and is the acute and chronic digestive system disease of one common clinically.The pathogenesis of gastric ulcer is very complicated.Chinese medicine thinks that gastric ulcer belongs to motherland's medical science " gastric abscess ", " acid regurgitation ", " feeling of fullness " category, and main clinical manifestation is stomachache, vomiting, feel sick and the symptom such as pantothenic acid.Theory of Chinese medical science is to the understanding of its etiology and pathogenesis: generation and liver that " Ling Shu Miraculous Pivot or Divine Axis pathogen cacosplanchnia shape " first proposes to have a stomachache, spleen are relevant.As " the hexa-atomic large opinion of just recording of Plain Questions " is said: " strongly fragrant the sending out of wood, the sick epigastralgia right below the heart of the people." " Plain Questions lift pain opinion " says: " cold is objective between the intestines and stomach.Blood can not fall apart, and little network is anxious to be drawn, therefore pain." " medical science main story gastric abscess " say: " and cause a disease by, how by self-indulgent food, it is sad to like, and throws off restraint the hot wine of drink and to eat again cold and cool raw food, damage dusk towards wound, amasss the moon dark therefore gastralgia day." generation of primary disease being described primarily of many factors as exopathogen violates stomach, diet injures one's stomach, the smooth and emptiness of spleen and stomach of feelings will etc., all can cause stagnation of stomach-QI, stomach-QI being unable to descend normally, transporting is unable, with the passing of time spleen and stomach function disorder, and QI-blood circulation is not normal, the stagnant stagnation of QI and blood may bring about pain of the stomach network stasis of blood.

Modern medicine is thought: under normal circumstances; the defense factor of the attack factor of gastric ulcer and protection gastric mucosa is caused to be in poised state; when a variety of causes causes attack factor enhancing or mucosal defense miopragia, this balance is broken, and gastric ulcer just can occur.

Current is chemical drugs treatment to the Therapeutic Method that gastric ulcer is main, can adopt omeprazole, motilium, amoxycillin with clavulanate potassium etc., or take operative therapy according to the state of an illness.But above-mentioned treatment generally can cause certain toxic and side effects, and relapse rate is high.Chinese medicine aspect, generally takes the tcm characteristic of organic conception and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.The traditional Chinese medical science is thought: gastric ulcer mainly by being invaded by exogenous pathogen, feelings will internal injury, diet without joint etc., thus the taste caused are injured, stomach-QI being unable to descend normally, the liver failing to maintain the normal flow of QI; Or because Deficiency and coldness of spleen and stomach and dysfunction of the spleen in transportation etc. cause.Method for the treatment of adopts stomach function regulating relieving stuffiness in the epigastrium, regulating QI to relieve pain, conciliation cold and heat.Belong to " and method " category in tcm treatment method.

Therefore, effectively gastric ulcer can be treated and the medicine had no side effect in the urgent need to a kind of.

Summary of the invention

Be applicable to medicine for the treatment of gastric ulcer and preparation method thereof easily to obtain effective and safe, the present inventor through clinical and studies of pharmacy a large amount of for a long time, after having carried out the interaction between sufficient clinical verification and Chinese medicine, has completed the present invention to this.

Chinese medical theory is thought: gastric ulcer is being invaded by exogenous pathogen mainly, feelings will internal injury, improper diet and overtiredness, and taste are injured, the liver failing to maintain the normal flow of QI, and perverse and unreasonable manner violates stomach, and gastric qi blocks, stomach-QI being unable to descend normally, stagnation of QI and blood may bring about pain; Or because of Deficiency and coldness of spleen and stomach, stomach-Yin virtual loss, dysfunction of the spleen in transportation, channels loses supports, and Rong Ze pain not caused.Therefore weakness of the spleen and stomach is the basic reason of Mechanism of Gastric Ulcer and recurrence.

For the understanding of the traditional Chinese medical science to gastric ulcer etiology and pathogenesis, in conjunction with modern medical theory, the invention provides a kind of medicine for the treatment of gastric ulcer.

The invention provides a kind of medicine for the treatment of gastric ulcer, comprise Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Coptidis, Radix Scutellariae, vinegar Rhizoma Corydalis, Radix Codonopsis, Radix Aucklandiae (roasted), Rhizoma Zingiberis, Endoconcha Sepiae, Bulbus Fritillariae Thunbergii, parched with bran Rhizoma Atractylodis, Radix Glycyrrhizae.

Exemplify as one is exemplary, in described pharmaceutical composition, with parts by weight, its concrete constituent content is as follows:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 6-20 part, Rhizoma Coptidis 3-20 part, Radix Scutellariae 6-20 part, vinegar Rhizoma Corydalis 6-30 part, Radix Codonopsis 10-50 part, Radix Aucklandiae (roasted) 6-30 part, Rhizoma Zingiberis 3-15 part, Endoconcha Sepiae 10-60 part, Bulbus Fritillariae Thunbergii 10-20 part, parched with bran Rhizoma Atractylodis 6-20 part, Radix Glycyrrhizae 3-20 part.

Further, medicine of the present invention has optimum ratio to be:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 12 parts, Rhizoma Coptidis 9 parts, Radix Scutellariae 12 parts, vinegar Rhizoma Corydalis 15 parts, Radix Codonopsis 12 parts, Radix Aucklandiae (roasted) 9 parts, Rhizoma Zingiberis 9 parts, Endoconcha Sepiae 15 parts, Bulbus Fritillariae Thunbergii 12 parts, parched with bran Rhizoma Atractylodis 9 parts, 12 parts, Radix Glycyrrhizae.

Treat a medicine for gastric ulcer as above, its preparation method is: 1), according to described weight portion take Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Coptidis, Radix Scutellariae, vinegar Rhizoma Corydalis, Radix Codonopsis, Radix Aucklandiae (roasted), Rhizoma Zingiberis, Endoconcha Sepiae, Bulbus Fritillariae Thunbergii, parched with bran Rhizoma Atractylodis, Radix Glycyrrhizae; 2), wherein Radix Aucklandiae (roasted), Rhizoma Zingiberis, parched with bran Rhizoma Atractylodis are pressed all the other 8 taste medicines in extraction by steam distillation volatile component, medicinal residues and prescription, add the water extraction 2 times of 10 ~ 20 times of weight, first time extracts 1 ~ 2 hour, second time 0.5 ~ 1.5 hour, merge extractive liquid, filters, centrifugal, leave standstill, get supernatant, concentrating under reduced pressure becomes relative density 1.19 ~ 1.50 clear paste; 3), by step 2) gained volatile component adds in clear paste, and mix homogeneously, obtains described medicine.

Preferably, step 1) in add the water of 15 times of weight, first time extracts 1.5 hours, and second time is extracted 1 hour.

Described process for preparing medicine can add medicine acceptable carrier conveniently technique, makes tablet, capsule, powder, pill, granule, soft capsule, drop pill, unguentum or oral liquid.

Wherein, the action and efficacy of major pharmaceutical component is:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens): pungent, warm; Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, is used for stopping nausea and vomiting by lowering the adverse flow of QI, regulates gastrointestinal function, the effect of anti-gastric-ulcer.

Rhizoma Coptidis: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle, antiinflammatory, antibacterial, antiulcer action.

Radix Scutellariae is bitter, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.

Vinegar Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.For costa sternales, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.There is the effects such as analgesia, calmness, antiulcer, gastric acid secretion inhibiting.

Radix Codonopsis: sweet is flat.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.Antiulcer, has protective effect to the damage of gastric mucosa.

Radix Aucklandiae (roasted): pungent, bitter, temperature.Return spleen, stomach, large intestine, three burnt, gallbladder meridians.Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, real intestinal antidiarrheal.For heavy after breast gastral cavity distending pain, dysentery, stomachache of having loose bowels, food stagnation does not disappear.Regulate the secretion of gastric mucosa, facilitating digestion.

Rhizoma Zingiberis: pungent, heat.Return spleen, stomach, kidney, the heart, lung meridian.Warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.Stomach-tonifying and pain alleviating effect.

Endoconcha Sepiae: salty, puckery, temperature.Return spleen, kidney channel.Astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore.For acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge: Peptic Ulcers, gastric acid secretion inhibiting.

Bulbus Fritillariae Thunbergii: bitter, cold.Return lung, heart channel.Heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing.For wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore, antibacterial, antiulcer action.

Parched with bran Rhizoma Atractylodis: pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi Wei lame, rheumatic arthralgia, anemofrigid cold, nyctalopia, antiulcer, Gastrointestinal motility adjustment function.

Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

Wherein, the present invention is directed to the understanding of the traditional Chinese medical science to gastric ulcer mechanism, described medicine cures mainly heresy and violates in stomach, stomach-QI being unable to descend normally, the diseases such as cold and heat are tied mutually, epigastric oppression and rigidity, gastralgia acid regurgitation.Described medicine enters stomach based on the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of acrid in the mouth hardship, pungently opens eliminating stagnation, and hardship falls preventing or arresting vomiting with the card except feeling of fullness vomiting; Be aided with the pungent temperature cold relieving of Rhizoma Zingiberis, Radix Scutellariae, Rhizoma Coptidis clearing up internal heat by using drugs of bitter in taste and cold in nature; Help with Radix Codonopsis strengthening QI of middle-JIAO, parched with bran Rhizoma Atractylodis the spleen strengthening and damp drying, burnt mechanism of qi in Radix Aucklandiae (roasted) fortune, the antacid of Bulbus Fritillariae Thunbergii clearing up internal heat by using drugs of bitter in taste and cold in nature eliminating stagnation, vinegar Rhizoma Corydalis, Endoconcha Sepiae relieving gastric hyperacidity to alleviate stomachache; Make with Radix Glycyrrhizae tonifying the spleen and stomach and adjust all medicines.All medicines match simultaneously using both cold and hot drugs, arduously go forward side by side, and reinforcing and reducing, with executing, become removing pathogen in the heart to disappear painful abdominal mass, invigorating middle warmer righting, the merit of cold and heat of being in harmonious proportion altogether.

Beneficial effect of the present invention:

A kind of medicine for the treatment of gastric ulcer of the present invention, coordination of cold and heat, dryness and dampness coordinating each other, follows the double therapeutic principle of traditional Chinese medicine executed of strengthening vital QI to eliminate pathogenic factors.In method for the treatment of based on method, also to embody in eight therapeutic methods temperature, clear, disappear, applying in a flexible way of mending, ingenious prescription reach with in curative effect.Globality and the dialectical nature of hepatopathy are fully experienced in the legislation of we, prescription, square medicine, and formula is unique, and determined curative effect, without obvious toxic-side effects.

Detailed description of the invention

Below by specific embodiment, the present invention is described in detail; but the purposes of these exemplary embodiments and object are only used for exemplifying the present invention; not any type of any restriction is formed to real protection scope of the present invention, more non-protection scope of the present invention is confined to this.

Embodiment 1

Treat a medicine for gastric ulcer, with parts by weight, its concrete constituent content is as follows:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 12 parts, Rhizoma Coptidis 15 parts, Radix Scutellariae 10 parts, vinegar Rhizoma Corydalis 15 parts, Radix Codonopsis 15 parts, Radix Aucklandiae (roasted) 20 parts, Rhizoma Zingiberis 6 parts, Endoconcha Sepiae 30 parts, Bulbus Fritillariae Thunbergii 15 parts, parched with bran Rhizoma Atractylodis 10 parts, 20 parts, Radix Glycyrrhizae.

Concrete preparation method is as follows:

1), Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Coptidis, Radix Scutellariae, vinegar Rhizoma Corydalis, Radix Codonopsis, Radix Aucklandiae (roasted), Rhizoma Zingiberis, Endoconcha Sepiae, Bulbus Fritillariae Thunbergii, parched with bran Rhizoma Atractylodis, Radix Glycyrrhizae is taken according to described weight portion; 2), wherein Radix Aucklandiae (roasted), Rhizoma Zingiberis, parched with bran Rhizoma Atractylodis are pressed all the other 8 taste medicines in extraction by steam distillation volatile component, medicinal residues and prescription, add the water extraction 2 times of 10 ~ 20 times of weight, first time extracts 1 ~ 2 hour, second time 0.5 ~ 1.5 hour, merge extractive liquid, filters, centrifugal, leave standstill, get supernatant, concentrating under reduced pressure becomes relative density 1.19 ~ 1.50 clear paste; 3), by step 2) gained volatile component adds in clear paste, and mix homogeneously, adds that medicine acceptable carrier makes any pharmaceutically useful preparation.

Described medicine is prepared as capsule.

Embodiment 2

Treat a medicine for gastric ulcer, in described pharmaceutical composition, with parts by weight, its concrete constituent content is as follows:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15 parts, Rhizoma Coptidis 20 parts, Radix Scutellariae 15 parts, vinegar Rhizoma Corydalis 10 parts, Radix Codonopsis 10 parts, Radix Aucklandiae (roasted) 25 parts, Rhizoma Zingiberis 15 parts, Endoconcha Sepiae 20 parts, Bulbus Fritillariae Thunbergii 20 parts, parched with bran Rhizoma Atractylodis 15 parts, 15 parts, Radix Glycyrrhizae.

Concrete preparation method is with embodiment 1.

Described medicine is prepared as oral liquid.

Embodiment 3

Treat a medicine for gastric ulcer, in described pharmaceutical composition, with parts by weight, its concrete constituent content is as follows:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 parts, Rhizoma Coptidis 22 parts, Radix Scutellariae 12 parts, vinegar Rhizoma Corydalis 13 parts, Radix Codonopsis 20 parts, Radix Aucklandiae (roasted) 25 parts, Rhizoma Zingiberis 14 parts, Endoconcha Sepiae 15 parts, Bulbus Fritillariae Thunbergii 15 parts, parched with bran Rhizoma Atractylodis 20 parts, 6 parts, Radix Glycyrrhizae.

Concrete preparation method is with embodiment 1.

Described medicine is prepared as slow releasing tablet.

Embodiment 4:

Treat a medicine for gastric ulcer, in described pharmaceutical composition, with parts by weight, its concrete constituent content is as follows:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18 parts, Rhizoma Coptidis 18 parts, Radix Scutellariae 10 parts, vinegar Rhizoma Corydalis 11 parts, Radix Codonopsis 13 parts, Radix Aucklandiae (roasted) 22 parts, Rhizoma Zingiberis 12 parts, Endoconcha Sepiae 20 parts, Bulbus Fritillariae Thunbergii 15 parts, parched with bran Rhizoma Atractylodis 10 parts, 9 parts, Radix Glycyrrhizae.

Concrete preparation method is with embodiment 1.

Described medicine is prepared as granule.

Embodiment 5:

Treat a medicine for gastric ulcer, in described pharmaceutical composition, with parts by weight, its concrete constituent content is as follows:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 parts, Rhizoma Coptidis 20 parts, Radix Scutellariae 10 parts, vinegar Rhizoma Corydalis 10 parts, Radix Codonopsis 10 parts, Radix Aucklandiae (roasted) 20 parts, Rhizoma Zingiberis 10 parts, Endoconcha Sepiae 20 parts, Bulbus Fritillariae Thunbergii 15 parts, parched with bran Rhizoma Atractylodis 10 parts, 20 parts, Radix Glycyrrhizae.

Concrete preparation method is with embodiment 1.

Described medicine is prepared as drop pill.

Clinical research and case:

Clinical research:

1. clinical data 1:

1.1 physical data: 58 routine gastric ulcer patients, wherein male 38 example, women 20 example; In age 22-78 year, all derive from the department of Chinese medicine outpatient service of 2009.04 ~ 2013.12 the courts, the course of disease-3 years on the 1st.

1.2 diagnostic criterias: " the gastric ulcer clinical criteria that Chinese Medical Association formulates ".

1.3 inclusive criterias: 1. gastroscopy shows clear and definite ulcer focus appearance; 2.. gastric ulcer sick time is within 20 years; 3.. the state of an illness is defined as gastric ulcer after diagnosing; 4. patient age is in 20-80 year; 5. add this research voluntarily.

1.4 exclusion standards: 1. pathological biopsy is malignant ulcer dubiety pathological changes patient; 2. gastric operation history is got rid of more than 6 months persons; 3. get rid of important organ (brain, the heart, liver, kidney) and have seriously former or secondary disease patient.

2. method:

2.1 Therapeutic Method:

According to embodiment 3, conveniently technique, make slow releasing tablet.Prescription is as follows:

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 parts, Rhizoma Coptidis 22 parts, Radix Scutellariae 12 parts, vinegar Rhizoma Corydalis 13 parts, Radix Codonopsis 20 parts, Radix Aucklandiae (roasted) 25 parts, Rhizoma Zingiberis 14 parts, Endoconcha Sepiae 15 parts, Bulbus Fritillariae Thunbergii 15 parts, parched with bran Rhizoma Atractylodis 20 parts, 6 parts, Radix Glycyrrhizae.

2.2 usings method:

Use medicine of the present invention, consumption is equivalent to potion on the one, divides and takes for 2 times.Within 7 days, be a course for the treatment of, statistics therapeutic effect, in table 1.

2.3 curative effect index:

Recovery from illness: gastroscopy result display gastric ulcer focus heals completely, and clinical symptoms performance disappears completely.

Effective: stomach pain frequency and number of times alleviate more than 2/3, gastroscopy result display gastric ulcer face reduces more than 2/3, treats in latter 1 year and does not recur.

Effective: stomach pain frequency and number of times alleviate more than 1/3, gastroscopy result display ulcer area reduce 1/3, treatment later six months in do not recur, gastric ulcer clinical symptoms performance take a turn for the better to some extent.

Invalid: not reach above-mentioned standard.Gastroscopy result display ulcer area without any change, or expands further, and the clinical needle-like performance of gastric ulcer is without any improvement, or the state of an illness increases the weight of further.

3. result:

Table 1. gastric ulcer patient treatment outcome 58 example (%)

Conclusion: courses of pharmaceuticals of the present invention is short, instant effect, treats 3 courses for the treatment of, both 21 days time, cure rate reaches 24.14%, and obvious effective rate then reaches 25.86%.

Clinical research 2

With omeprazole clinical evaluation:

Physical data: by qualified patients w ith peptic ulcer disease 116 example, be divided into observation group and matched group at random, often organizes 58 examples, observation group's mean age (40.5 ± 6.0) year, man 45 example, female 13 example.The matched group mean age (41.5 ± 6.0) year, man 36 example, female 22 example.Two groups of patients are unanimous on the whole in sex, age, the course of disease and ulcer etc.

Group is arranged: matched group: each dosage 20mg of Omeprazole Enteric-coated Tablets (the how precious Pharmaceutical in Jiangsu), every day 2 times, early morning and (medicine) being taken before meal use before sleeping.

Observation group: medicine of the present invention is as embodiment 3, and every day 1 dose, point 2 clothes, take 3 weeks continuously.

Result:

Two groups of patient's comparitive study (routine %)

Group	Number of cases	Recovery from illness	Effective	Effectively	Invalid	Total effective rate
							Observation group	58	14(24.14)	15(25.86)	22(37.93)	7(12.07)	51(87.93)
Matched group	58	13(22.41)	23(39.65)	11(18.97)	11(18.97)	47(81.03)

Case:

Case 1:

Grandson, man, 43 years old.First visit on April 12 in 2009.

Patient is because distention and fullness in the abdomen is uncomfortable over nearly more than 20 days, and the companion body is weak, loss of appetite, loses weight, and light red tongue tongue is white, stringy pulse.Gastroscopy: the slight ulcer of stomach, HP (+), through the oral motilium of western medical treatment, omeprazole 2 weeks, has no positive effect.Be diagnosed as: gastric ulcer.

Dialectical: incoordination between the liver and stomach, stagnation of QI due to depression of the liver.

Method for the treatment of: depressed liver-energy dispersing and QI regulating, promoting the circulation of QI to relieve pain.

Prescription: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20g Rhizoma Coptidis 20g Radix Scutellariae 10g vinegar Rhizoma Corydalis 10g Radix Codonopsis 10g Radix Aucklandiae (roasted) 20g Rhizoma Zingiberis 9g Endoconcha Sepiae 20g Bulbus Fritillariae Thunbergii 15g parched with bran Rhizoma Atractylodis 10g Radix Glycyrrhizae 20g.

Above-mentioned prescription conveniently technique adds customary adjuvant and makes oral liquid.Be more than every daily dose, every day 2 times.

Two examine: April 20, after medicine, abdominal distention obviously alleviates, red tongue, white and thin fur, stringy pulse, and top following the service 7 pairs takes 2 courses for the treatment of altogether, and May 21 followed up a case by regular visits to: patients symptomatic disappears substantially, clinical cure.

Case 2

Fourth so-and-so, man, 40 years old.First visit in February 26 in 20013.

Pinprick sample pain under xiphoid-process after drinking before patient's first quarter moon, without radiating pain, continues about 30 minutes, can alleviate after feed, sense is felt sick, without vomitting; Sense acid regurgitation is heartburn, without heating shiver with cold, without dizziness headache, without hemoptysis, without cough and expectoration, without chest distress, without chest pain, without abdominal pain and distension, without hematemesis, stops without passage of gas by anus defecation.Body weight is without obviously alleviating.Carry out my Out-patient Department to go to a doctor, gastroscope shows: stomach ulcer.Pathology shows: HP (++).Be diagnosed as: gastric ulcer.

Dialectical: incoordination between the liver and stomach, obstruction of collaterals by blood stasis.

Method for the treatment of: removing obstruction in the collateral to relieve pain.

Prescription: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 9g Rhizoma Coptidis 3g Radix Scutellariae 9g vinegar Rhizoma Corydalis 15g Radix Codonopsis 15g Radix Aucklandiae (roasted) 20g Rhizoma Zingiberis 10g Endoconcha Sepiae 30g Bulbus Fritillariae Thunbergii 12g parched with bran Rhizoma Atractylodis 15g Radix Glycyrrhizae 9g.

Above-mentioned prescription conveniently technique adds customary adjuvant and makes granule.Be more than oral dose every day, every day 2 times.Through the treatment of 30 days, recovery from illness.

Case 3

Zhao so-and-so, female, 63 years old, May 8 in 2012 order go to a doctor

Patient's gastralgia catch cropping more than 1 year, Chang Yu increases the weight of before the meal, companion pantothenic acid, belch, pain pain relieved by pressing, and distention and fullness in the abdomen is uncomfortable, because causing gastral cavilty portion pain to connect after housework dispute anger and two side of body flanks before 3 days, dry mouth with bitter taste, distension and fullness in the abdomen, poor appetite, be convenient to greatly tongue dark red, tongue is white, wiry and frequent pulse.Gastroscope: gastric ulcer.Pathology shows HP (-).Be diagnosed as: gastric ulcer.

Dialectical: stagnation of QI due to depression of the liver.

Method for the treatment of: dispersing the stagnated live-QI to relieve the stagnation of QI, regulating QI to relieve pain.

Prescription: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15g Rhizoma Coptidis 9g Radix Scutellariae 15g vinegar Rhizoma Corydalis 15g Radix Codonopsis 15g Radix Aucklandiae (roasted) 30g Rhizoma Zingiberis 6g Endoconcha Sepiae 30g Bulbus Fritillariae Thunbergii 20g parched with bran Rhizoma Atractylodis 15g Radix Glycyrrhizae 15g.

Above-mentioned prescription conveniently technique adds customary adjuvant and makes pill.Be more than oral dose every day, every day 2 times.Take medicine clinical symptom disappearance after 3 courses for the treatment of, sign is clearly better, and does not recur again.

Claims (5)

1. treat a medicine for gastric ulcer, it is characterized in that: described medicine comprises Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Coptidis, Radix Scutellariae, vinegar Rhizoma Corydalis, Radix Codonopsis, Radix Aucklandiae (roasted), Rhizoma Zingiberis, Endoconcha Sepiae, Bulbus Fritillariae Thunbergii, parched with bran Rhizoma Atractylodis, Radix Glycyrrhizae.

2. a kind of medicine for the treatment of gastric ulcer according to claim 1, it is characterized in that, each component of described medicine according to parts by weight is: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 6-20 part, Rhizoma Coptidis 3-20 part, Radix Scutellariae 6-20 part, vinegar Rhizoma Corydalis 6-30 part, Radix Codonopsis 10-50 part, Radix Aucklandiae (roasted) 6-30 part, Rhizoma Zingiberis 3-15 part, Endoconcha Sepiae 10-60 part, Bulbus Fritillariae Thunbergii 10-20 part, parched with bran Rhizoma Atractylodis 6-20 part, Radix Glycyrrhizae 3-20 part.

3. a kind of medicine for the treatment of gastric ulcer as claimed in claim 1 or 2, it is characterized in that, each component of described medicine according to parts by weight is: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 12 parts, Rhizoma Coptidis 9 parts, Radix Scutellariae 12 parts, vinegar Rhizoma Corydalis 15 parts, Radix Codonopsis 12 parts, Radix Aucklandiae (roasted) 9 parts, Rhizoma Zingiberis 9 parts, Endoconcha Sepiae 15 parts, Bulbus Fritillariae Thunbergii 12 parts, parched with bran Rhizoma Atractylodis 9 parts, 12 parts, Radix Glycyrrhizae.

4. a kind of medicine for the treatment of gastric ulcer as claimed in claim 1, its preparation method is: 1), according to described weight portion take Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Coptidis, Radix Scutellariae, vinegar Rhizoma Corydalis, Radix Codonopsis, Radix Aucklandiae (roasted), Rhizoma Zingiberis, Endoconcha Sepiae, Bulbus Fritillariae Thunbergii, parched with bran Rhizoma Atractylodis, Radix Glycyrrhizae; 2), wherein Radix Aucklandiae (roasted), Rhizoma Zingiberis, parched with bran Rhizoma Atractylodis are pressed all the other 8 taste medicines in extraction by steam distillation volatile component, medicinal residues and prescription, add the water extraction 2 times of 10 ~ 20 times of weight, first time extracts 1 ~ 2 hour, second time 0.5 ~ 1.5 hour, merge extractive liquid, filters, centrifugal, leave standstill, get supernatant, concentrating under reduced pressure becomes relative density 1.19 ~ 1.50 clear paste; 3), by step 2) gained volatile component adds in clear paste, and mix homogeneously, obtains described medicine.

5. a kind of medicine for the treatment of gastric ulcer as claimed in claim 1, is characterized in that: described medicine is the one in tablet, capsule, powder, pill, granule, soft capsule, drop pill, unguentum, oral liquid.