CN104800537A - Traditional Chinese medicine composition for treating alopecia with hair-blacking function and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating alopecia with hair-blacking function and preparation method thereof Download PDF

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CN104800537A
CN104800537A CN201510240959.7A CN201510240959A CN104800537A CN 104800537 A CN104800537 A CN 104800537A CN 201510240959 A CN201510240959 A CN 201510240959A CN 104800537 A CN104800537 A CN 104800537A
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radix
medicine composition
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fructus
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CN104800537B (en
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谭树华
聂娜
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BEIJING PUSHIAN BIOTECHNOLOGY Co.,Ltd.
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Hunan University of Science and Technology
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Abstract

The invention belongs to the technical field of traditional Chinese medicine, in particular relates to a traditional Chinese medicine composition for treating alopecia with a hair-blacking function and a preparation method thereof. The traditional Chinese medicine composition comprises an orally taken traditional Chinese medicine composition and an externally used traditional Chinese medicine composition. The traditional Chinese medicine composition achieves the effects of treating the alopecia with the hair-blacking function by adoption of the combination of the oral use and the external use of the composition through carefully selecting each active pharmaceutical ingredient and the ratio based on the theory of traditional Chinese medicine and the balanced nutrition principle and proved by practice researches of many years; in addition, the traditional Chinese medicine composition can make hairs more black and bright along with remarkable effect; the traditional Chinese medicine composition has the advantages of remarkable effect, capability of treating both symptoms and root causes, good effect, quick results, low cost, convenience in use and no toxic or side effects.

Description

A kind of hair growth also has Chinese medicine composition of black hair function and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of hair growth and there is Chinese medicine composition of black hair function and preparation method thereof.
Background technology
China's alopecia and white hair symptom has increasing trend in recent years, especially more general with male pattern baldness poliosis, and has occurred the impetus that becomes younger.There is data to show, within less than 30 years old, have more than half all by the puzzlement of being alopecia in male.According to city sample survey, China's middle age (35 ~ 59 years old) poliosis, alopecia sickness rate are up to 45.7%.
Alopecia is a kind of common dermatosis, can be divided into seborrheic alopecia (also known as seborrheic alopecia, male pattern alopecia) alopecia areata, alopecia totalis etc.Common alopecia is mostly seborrheic alopecia (accounting for hair loss patient more than 95%), and its symptom is the excessive spilling of patient's scalp fat, causes the greasy humidity of hair, sometimes also the inflammation such as to scratch where it itches with scalp.Poliosis is one of physiological change of aging, and by 40 years old, later hair was bleached by black common people naturally gradually.The traditional Chinese medical science thinks blood stored in the liver, hair is the sign of blood condition, the kidney generating marrow and dominating bone, its honor is being sent out, it is strong that vim and vigour contain then kidney qi, kidney qi bone strengthening marrow is full of, and hair is black and glossy, and vim and vigour void then kidney qi is weak, vim and vigour can not be gone, send out and then withered and yellowly to come off without pool, therefore think alopecia, the formation of poliosis and deficiency of the liver and kindey, weak constitution, debility is relevant.Simultaneously, people by internal injury caused by excess of seven emotions, depressed emotion, the impairment of the spleen of working with one's mind, to affect vim and vigour running smooth and cause qi depression to blood stasis, hair loses nutrition and comes off, the organism endocrine of this and modern medicine study and immunologic derangement is lacked of proper care, the factor such as psychic trauma and hypertonicity, blood vessel and disturbance of blood circulation, cause trichotrophy obstacle and alopecia, poliosis identical of views.Alopecia, poliosis are not only relevant with the pathological changes of hair itself, also by heredity, the impact of the many factors such as healthy, nutrition is unbalanced, trace element deficiency, Bad Eating Habit and hormonal readiness, and relevant with the infection of Nervous and Mental Factors, endocrine factors, internal organs disease, medicine, various pathogens etc.
Modern medicine study is thought, poliosis is formed mainly due to hair melanin and reduces, and melanocyte synthetic dyestuff granule miopragia, caused by the reduced activity of tryrosinase.Occur that poliosis is relevant with Nervous and Mental Factors and inherited genetic factors, Nervous and Mental Factors can make the blood vessel generation contracture of supply hair, makes the hair papilla of hair root manufacture melanic function generation obstacle, though or create melanin, input the channel of hair shaft and be obstructed.Also the poliosis of a few peoples is had to cause due to Liver and kidney deficiency of both QI and blood or certain reason such as special disease and nutrient deficiency.Treat with blood circulation promoting and blood stasis dispelling, the qualcomm meridian that relaxes, nourish Rhizoma Imperatae, promote the melanic regeneration of hair follicle and utilization, and nourishing the liver and kidney is to strengthen the growth function of hair for principle.Clinical detection shows in recent years, and in alopecia, poliosis patients serum, Endothelin (ET) content is apparently higher than normal person.This local vascular can be caused strongly to send out contracting spasm and cause stem blood supply reduce material, hair exhaustion can be caused to come off or bleach.Hair blood flow detection also confirms, hair loss patient scalp not only changes with medical science in a organized way, and also there is resistance of blood flow high, blood flow total amount is few, the abnormal phenomena of effectively perfusion minimizing.
From threpsology's theory, the main cause of alopecia and white hair has be staple food and fruit and vegetable Deficiency of Intake cause deficiency of qi and blood, deficiency of kidney-QI at two: one.Successive dynasties expert in health preserving advocates healthy dietary requirement " for filling, five fruits are foster to grain rice " always.Namely human body must take in a certain amount of staple food and fruit and vegetable every day, but nearest portion investigation shows, the staple food consumption figure of modern city people is fewer and feweri, and the gesture of existing deficiency, easily causes deficiency of qi and blood, deficiency of kidney-QI; Two is carnivorous absorptions too much, makes kidney qi impaired, easily cause seborrheic alopecia and poliosis because nutrition is unbalanced.More than can find out, the traditional Chinese medical science is consistent with the alopecia reason of the theoretical explanation of threpsology.
At present, medicine for preventing and treating alopecia and poliosis on market is a lot, but there is the weak points such as onset is slow, the course for the treatment of long, easy recurrence, limited efficiency more, and major part only has certain curative effect to pathologic alopecia, function ratio is more single, rarely has both the product of anticreep and black hair function.In addition, due to poliosis treatment product limited efficiency, most people adopts chemical hair dye to cover poliosis phenomenon, and the p-phenylenediamine (PPD) in chemical hair dye is carcinogen, there is very strong sensitization, contact scalp can enter in human body by hair follicle, causes the condition of illness such as skin allergy, contact dermatitis eczema, leukemia, bronchial asthma.
As can be seen here, a kind of efficient hair growth can be invented and there is the Chinese medicine composition of black hair function, becoming the technical barrier that those skilled in the art receive solution.
Summary of the invention
The present invention is in order to solve the problems of the technologies described above, according to theory of Chinese medical science and principle balanced in nutrition, through practical studies for many years, invent a kind for the treatment of both the principal and secondary aspects of a disease, effective, instant effect, cost is low, easy to use, the oral administration and externally Chinese medicine composition that has no side effect, possesses control alopecia and blackening hair effect simultaneously.
In order to reach above-mentioned technique effect, technical scheme of the present invention comprises:
A kind of hair growth also has the Chinese medicine composition of black hair function, described Chinese medicine composition comprises oral preparations Chinese medicine composition and external medicine composition, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 10 ~ 30 parts, Folium Pini, Herba Ecliptae 10 ~ 30 parts, 10 ~ 30 parts, Fructus Mori, Herba Taraxaci 10 ~ 20 parts, Semen Sesami Nigrum 20 ~ 40 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Radix Salviae Miltiorrhizae 5 ~ 15 parts, 10 ~ 20 parts, Folium Mori, Semen Cassiae 20 ~ 30 parts, Herba Hedyotidis Diffusae 15 ~ 25 parts, Fructus Psoraleae 10 ~ 30 parts, the Radix Astragali 10 ~ 25 parts, Radix Puerariae 10 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 20 parts, 10 ~ 25 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 20 ~ 40 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, 8 ~ 15 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 10 ~ 20 parts, Cacumen Platycladi 15 ~ 25 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 10 ~ 30 parts, Radix Et Rhizoma Rhei 15 ~ 25 parts, 20 ~ 40 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 20 ~ 30 parts, the raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 50 ~ 80 parts, 30 ~ 60 parts, Semen sojae atricolor, Semen Sesami Nigrum 20 ~ 40 parts, the Radix Astragali 10 ~ 30 parts, Ganoderma 10 ~ 20 parts, 20 ~ 30 parts, Fructus Mori, Herba Ecliptae 15 ~ 30 parts, Fructus Psoraleae 10 ~ 30 parts, Cacumen Platycladi 15 ~ 35 parts, 20 ~ 40 parts, Folium Pini, Fructus Gleditsia 10 ~ 20 parts, 20 ~ 30 parts, the Radix Rehmanniae, Herba Menthae 10 ~ 15 parts, Fructus Tribuli 20 ~ 30 parts.
Preferably, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 20 parts, Folium Pini, Herba Ecliptae 20 parts, 20 parts, Fructus Mori, Herba Taraxaci 15 parts, Semen Sesami Nigrum 30 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Salviae Miltiorrhizae 10 parts, 12 parts, Folium Mori, Semen Cassiae 25 parts, Herba Hedyotidis Diffusae 20 parts, Fructus Psoraleae 20 parts, the Radix Astragali 15 parts, Radix Puerariae 15 parts, Fructus Ligustri Lucidi 15 parts, 15 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 30 parts, Radix Sophorae Flavescentis 15 parts, 12 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 15 parts, Cacumen Platycladi 20 parts, 12 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 parts, Radix Et Rhizoma Rhei 20 parts, 30 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 25 parts; The raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 65 parts, 45 parts, Semen sojae atricolor, Semen Sesami Nigrum 30 parts, the Radix Astragali 20 parts, Ganoderma 15 parts, 25 parts, Fructus Mori, Herba Ecliptae 25 parts, Fructus Psoraleae 20 parts, Cacumen Platycladi 22 parts, 30 parts, Folium Pini, Fructus Gleditsia 15 parts, 25 parts, the Radix Rehmanniae, Herba Menthae 12 parts, Fructus Tribuli 25 parts.
Described external medicine composition also comprises solvent and mantoquita.
Described solvent is second alcohol and water.
In described external medicine composition, the concentration of mantoquita is 0.02 ~ 0.06g/L.
Hair growth also has the preparation method of the Chinese medicine composition of black hair function, comprises the following steps:
Step one: prepare oral preparations Chinese medicine composition: the raw material components taking following parts by weight: 10 ~ 30 parts, Folium Pini, Herba Ecliptae 10 ~ 30 parts, 10 ~ 30 parts, Fructus Mori, Herba Taraxaci 10 ~ 20 parts, Semen Sesami Nigrum 20 ~ 40 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Radix Salviae Miltiorrhizae 5 ~ 15 parts, 10 ~ 20 parts, Folium Mori, Semen Cassiae 20 ~ 30 parts, Herba Hedyotidis Diffusae 15 ~ 25 parts, Fructus Psoraleae 10 ~ 30 parts, the Radix Astragali 10 ~ 25 parts, Radix Puerariae 10 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 20 parts, 10 ~ 25 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 20 ~ 40 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, 8 ~ 15 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 10 ~ 20 parts, Cacumen Platycladi 15 ~ 25 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 10 ~ 30 parts, Radix Et Rhizoma Rhei 15 ~ 25 parts, 20 ~ 40 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 20 ~ 30 parts, each component is dry, pulverized 10 ~ 30 mesh sieves, obtain coarse powder, by the described coarse powder mix homogeneously obtained, dry heat sterilization, pack, specification is 8 ~ 10g/ bag,
Step 2: prepare external medicine composition: the raw material components taking following parts by weight: Radix Polygoni Multiflori 50 ~ 80 parts, 30 ~ 60 parts, Semen sojae atricolor, Semen Sesami Nigrum 20 ~ 40 parts, the Radix Astragali 10 ~ 30 parts, Ganoderma 10 ~ 20 parts, 20 ~ 30 parts, Fructus Mori, Herba Ecliptae 15 ~ 30 parts, Fructus Psoraleae 10 ~ 30 parts, Cacumen Platycladi 15 ~ 35 parts, 20 ~ 40 parts, Folium Pini, Fructus Gleditsia 10 ~ 20 parts, 20 ~ 30 parts, the Radix Rehmanniae, Herba Menthae 10 ~ 15 parts, Fructus Tribuli 20 ~ 30 parts, coarse powder is ground into by after above-mentioned each component mixing, the ethanol that mass fraction is 50 ~ 75% is added according to described coarse powder and ethanol 1:8 (W/V) ratio, soak after 7 days, filter, leave filtrate and medicinal residues respectively, to add distilled water immersion in described medicinal residues after 12 ~ 24 hours, the volume ratio of described medicinal residues and described distilled water is 1:2 ~ 1:4, and temperature fire heating 15 minutes, is cooled to room temperature, filters, obtain filtrate, the filtrate obtained twice is mixed into solution, adjust 5 times that described overall solution volume is described coarse powder volume, and the mass percent making ethanol account for described solution is 10 ~ 20%, then add mantoquita in above-mentioned filtrate, make the concentration of mantoquita in described external medicine composition be 0.02 ~ 0.06g/L.
A kind of hair growth also has the application method of the Chinese medicine composition of black hair function, described oral preparations Chinese medicine composition is brewed 10 ~ 15min through boiling boiled water, brew 8 ~ 10g at every turn, one day twice, after hair washing, described external medicine composition uniform application is also massaged gently in alopecia position and absorb completely to medicine for 5 ~ 10 minutes, each medication 4 ~ 7ml, every day 1 ~ 2 time.
Beneficial effect of the present invention comprises: the present invention is according to theory of Chinese medical science and principle balanced in nutrition, through practical studies for many years, choose each crude drug and proportioning thereof, and the medicining mode adopting oral administration and externally to combine, reach hair growth and there is black hair functional effect, and make hair more pitch-black glossy, Be very effective, has treating both the principal and secondary aspects of a disease, effective, instant effect, cost is low, easy to use, the advantage that has no side effect.
Detailed description of the invention
Hereafter specifically will describe the specific embodiment of the invention in detail.It should be noted that the combination of technical characteristic or the technical characteristic described in following embodiment should not be considered to isolated, they can mutually be combined thus be reached better technique effect.
Embodiment 1
A kind of hair growth also has the Chinese medicine composition of black hair function, described Chinese medicine composition comprises oral preparations Chinese medicine composition and external medicine composition, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 10 parts, Folium Pini, Herba Ecliptae 10 parts, 30 parts, Fructus Mori, Herba Taraxaci 10 parts, Semen Sesami Nigrum 40 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Salviae Miltiorrhizae 15 parts, 10 parts, Folium Mori, Semen Cassiae 30 parts, Herba Hedyotidis Diffusae 15 parts, Fructus Psoraleae 30 parts, the Radix Astragali 10 parts, Radix Puerariae 25 parts, Fructus Ligustri Lucidi 10 parts, 25 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 20 parts, Radix Sophorae Flavescentis 20 parts, 8 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 20 parts, Cacumen Platycladi 15 parts, 15 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 10 parts, Radix Et Rhizoma Rhei 25 parts, 20 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 30 parts, the raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 50 parts, 60 parts, Semen sojae atricolor, Semen Sesami Nigrum 20 parts, the Radix Astragali 30 parts, Ganoderma 10 parts, 30 parts, Fructus Mori, Herba Ecliptae 15 parts, Fructus Psoraleae 30 parts, Cacumen Platycladi 15 parts, 40 parts, Folium Pini, Fructus Gleditsia 10 parts, 30 parts, the Radix Rehmanniae, Herba Menthae 10 parts, Fructus Tribuli 30 parts.
Described external medicine composition also comprises solvent and mantoquita, and described solvent is second alcohol and water.In described external medicine composition, the concentration of mantoquita is 0.02 ~ 0.06g/L.
Hair growth also has the preparation method of the Chinese medicine composition of black hair function, and described preparation method, comprises the following steps:
Step one: prepare oral preparations Chinese medicine composition: the raw material components taking following parts by weight: 10 parts, Folium Pini, Herba Ecliptae 10 parts, 30 parts, Fructus Mori, Herba Taraxaci 10 parts, Semen Sesami Nigrum 40 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Salviae Miltiorrhizae 15 parts, 10 parts, Folium Mori, Semen Cassiae 30 parts, Herba Hedyotidis Diffusae 15 parts, Fructus Psoraleae 30 parts, the Radix Astragali 10 parts, Radix Puerariae 25 parts, Fructus Ligustri Lucidi 10 parts, 25 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 20 parts, Radix Sophorae Flavescentis 20 parts, 8 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 20 parts, Cacumen Platycladi 15 parts, 15 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 10 parts, Radix Et Rhizoma Rhei 25 parts, 20 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 30 parts, each component is dry, pulverized 10 ~ 30 mesh sieves, obtain coarse powder, by the described coarse powder mix homogeneously obtained, dry heat sterilization, pack, specification is 8 ~ 10g/ bag,
Step 2: prepare external medicine composition: the raw material components taking following parts by weight: Radix Polygoni Multiflori 50 parts, 60 parts, Semen sojae atricolor, Semen Sesami Nigrum 20 parts, the Radix Astragali 30 parts, Ganoderma 10 parts, 30 parts, Fructus Mori, Herba Ecliptae 15 parts, Fructus Psoraleae 30 parts, Cacumen Platycladi 15 parts, 40 parts, Folium Pini, Fructus Gleditsia 10 parts, 30 parts, the Radix Rehmanniae, Herba Menthae 10 parts, Fructus Tribuli 30 parts, is ground into coarse powder by after above-mentioned each component mixing, the ethanol that mass fraction is 50 ~ 75% is added according to described coarse powder and ethanol 1:8 (W/V) ratio, soak after 7 days, filter, leave filtrate and medicinal residues respectively; To add distilled water immersion in described medicinal residues after 12 ~ 24 hours, the volume ratio of described medicinal residues and described distilled water is 1:2 ~ 1:4, and temperature fire heating 15 minutes, is cooled to room temperature, filters, obtain filtrate; The filtrate obtained twice is mixed into solution, adjust 5 times that described overall solution volume is described coarse powder volume, and the mass percent making ethanol account for described solution is 10 ~ 20%, then add mantoquita in above-mentioned filtrate, make the concentration of mantoquita in described external medicine composition be 0.02 ~ 0.06g/L.
A kind of hair growth also has the application method of the Chinese medicine composition of black hair function, described oral preparations Chinese medicine composition is brewed 10 ~ 15min through boiling boiled water, brew 8 ~ 10g at every turn, one day twice, after hair washing, described external medicine composition uniform application is also massaged gently in alopecia position and absorb completely to medicine for 5 ~ 10 minutes, each medication 4 ~ 7ml, every day 1 ~ 2 time.Above oral and external application medicine is taken simultaneously, and within 7 days, can control the fuel-displaced and pruritus of scalp, within 10 days, depilation phenomenon obviously reduces, and within 30 days, is a course for the treatment of, hair growth promoting general 1 ~ 3 course for the treatment of, 3 ~ 6 courses for the treatment of of blackening hair.
Embodiment 2
A kind of hair growth also has the Chinese medicine composition of black hair function, described Chinese medicine composition comprises oral preparations Chinese medicine composition and external medicine composition, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 20 parts, Folium Pini, Herba Ecliptae 20 parts, 20 parts, Fructus Mori, Herba Taraxaci 15 parts, Semen Sesami Nigrum 30 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Salviae Miltiorrhizae 10 parts, 12 parts, Folium Mori, Semen Cassiae 25 parts, Herba Hedyotidis Diffusae 20 parts, Fructus Psoraleae 20 parts, the Radix Astragali 15 parts, Radix Puerariae 15 parts, Fructus Ligustri Lucidi 15 parts, 15 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 30 parts, Radix Sophorae Flavescentis 15 parts, 12 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 15 parts, Cacumen Platycladi 20 parts, 12 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 parts, Radix Et Rhizoma Rhei 20 parts, 30 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 25 parts, the raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 65 parts, 45 parts, Semen sojae atricolor, Semen Sesami Nigrum 30 parts, the Radix Astragali 20 parts, Ganoderma 15 parts, 25 parts, Fructus Mori, Herba Ecliptae 25 parts, Fructus Psoraleae 20 parts, Cacumen Platycladi 22 parts, 30 parts, Folium Pini, Fructus Gleditsia 15 parts, 25 parts, the Radix Rehmanniae, Herba Menthae 12 parts, Fructus Tribuli 25 parts.
Described external medicine composition also comprises solvent and mantoquita, and described solvent is second alcohol and water.In described external medicine composition, the concentration of mantoquita is 0.02 ~ 0.06g/L.
Hair growth also has the preparation method of the Chinese medicine composition of black hair function, and described preparation method, comprises the following steps:
Step one: prepare oral preparations Chinese medicine composition: the raw material components taking following parts by weight: 20 parts, Folium Pini, Herba Ecliptae 20 parts, 20 parts, Fructus Mori, Herba Taraxaci 15 parts, Semen Sesami Nigrum 30 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Salviae Miltiorrhizae 10 parts, 12 parts, Folium Mori, Semen Cassiae 25 parts, Herba Hedyotidis Diffusae 20 parts, Fructus Psoraleae 20 parts, the Radix Astragali 15 parts, Radix Puerariae 15 parts, Fructus Ligustri Lucidi 15 parts, 15 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 30 parts, Radix Sophorae Flavescentis 15 parts, 12 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 15 parts, Cacumen Platycladi 20 parts, 12 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 parts, Radix Et Rhizoma Rhei 20 parts, 30 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 25 parts, each component is dry, pulverized 10 ~ 30 mesh sieves, obtain coarse powder, by the described coarse powder mix homogeneously obtained, dry heat sterilization, pack, specification is 8 ~ 10g/ bag,
Step 2: prepare external medicine composition: the raw material components taking following parts by weight:: Radix Polygoni Multiflori 65 parts, 45 parts, Semen sojae atricolor, Semen Sesami Nigrum 30 parts, the Radix Astragali 20 parts, Ganoderma 15 parts, 25 parts, Fructus Mori, Herba Ecliptae 25 parts, Fructus Psoraleae 20 parts, Cacumen Platycladi 22 parts, 30 parts, Folium Pini, Fructus Gleditsia 15 parts, 25 parts, the Radix Rehmanniae, Herba Menthae 12 parts, Fructus Tribuli 25 parts, is ground into coarse powder by after above-mentioned each component mixing, the ethanol that mass fraction is 50 ~ 75% is added according to described coarse powder and ethanol 1:8 (W/V) ratio, soak after 7 days, filter, leave filtrate and medicinal residues respectively; To add distilled water immersion in described medicinal residues after 12 ~ 24 hours, the volume ratio of described medicinal residues and described distilled water is 1:2 ~ 1:4, and temperature fire heating 15 minutes, is cooled to room temperature, filters, obtain filtrate; The filtrate obtained twice is mixed into solution, adjust 5 times that described overall solution volume is described coarse powder volume, and the mass percent making ethanol account for described solution is 10 ~ 20%, then add mantoquita in above-mentioned filtrate, make the concentration of mantoquita in described external medicine composition be 0.02 ~ 0.06g/L.
A kind of hair growth also has the application method of the Chinese medicine composition of black hair function, described oral preparations Chinese medicine composition is brewed 10 ~ 15min through boiling boiled water, brew 8 ~ 10g at every turn, one day twice, after hair washing, described external medicine composition uniform application is also massaged gently in alopecia position and absorb completely to medicine for 5 ~ 10 minutes, each medication 4 ~ 7ml, every day 1 ~ 2 time.Above oral and external application medicine is taken simultaneously, and within 7 days, can control the fuel-displaced and pruritus of scalp, within 10 days, depilation phenomenon obviously reduces, and within 30 days, is a course for the treatment of, hair growth promoting general 1 ~ 3 course for the treatment of, 3 ~ 6 courses for the treatment of of blackening hair.
Embodiment 3
A kind of hair growth also has the Chinese medicine composition of black hair function, described Chinese medicine composition comprises oral preparations Chinese medicine composition and external medicine composition, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 30 parts, Folium Pini, Herba Ecliptae 30 parts, 10 parts, Fructus Mori, Herba Taraxaci 20 parts, Semen Sesami Nigrum 20 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Radix Salviae Miltiorrhizae 5 parts, 20 parts, Folium Mori, Semen Cassiae 20 parts, Herba Hedyotidis Diffusae 25 parts, Fructus Psoraleae 10 parts, the Radix Astragali 25 parts, Radix Puerariae 10 parts, Fructus Ligustri Lucidi 20 parts, 10 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 40 parts, Radix Sophorae Flavescentis 30 parts, 15 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 10 parts, Cacumen Platycladi 25 parts, 10 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 30 parts, Radix Et Rhizoma Rhei 15 parts, 40 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 20 parts, the raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 80 parts, 30 parts, Semen sojae atricolor, Semen Sesami Nigrum 40 parts, the Radix Astragali 10 parts, Ganoderma 20 parts, 20 parts, Fructus Mori, Herba Ecliptae 30 parts, Fructus Psoraleae 10 parts, Cacumen Platycladi 35 parts, 20 parts, Folium Pini, Fructus Gleditsia 20 parts, 20 parts, the Radix Rehmanniae, Herba Menthae 15 parts, Fructus Tribuli 20 parts.
Described external medicine composition also comprises solvent and mantoquita, and described solvent is second alcohol and water.In described external medicine composition, the concentration of mantoquita is 0.02 ~ 0.06g/L.
Hair growth also has the preparation method of the Chinese medicine composition of black hair function, and described preparation method, comprises the following steps:
Step one: prepare oral preparations Chinese medicine composition: the raw material components taking following parts by weight: 30 parts, Folium Pini, Herba Ecliptae 30 parts, 10 parts, Fructus Mori, Herba Taraxaci 20 parts, Semen Sesami Nigrum 20 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Radix Salviae Miltiorrhizae 5 parts, 20 parts, Folium Mori, Semen Cassiae 20 parts, Herba Hedyotidis Diffusae 25 parts, Fructus Psoraleae 10 parts, the Radix Astragali 25 parts, Radix Puerariae 10 parts, Fructus Ligustri Lucidi 20 parts, 10 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 40 parts, Radix Sophorae Flavescentis 30 parts, 15 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 10 parts, Cacumen Platycladi 25 parts, 10 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 30 parts, Radix Et Rhizoma Rhei 15 parts, 40 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 20 parts, each component is dry, pulverized 10 ~ 30 mesh sieves, obtain coarse powder, by the described coarse powder mix homogeneously obtained, dry heat sterilization, pack, specification is 8 ~ 10g/ bag,
Step 2: prepare external medicine composition: the raw material components taking following parts by weight: Radix Polygoni Multiflori 80 parts, 30 parts, Semen sojae atricolor, Semen Sesami Nigrum 40 parts, the Radix Astragali 10 parts, Ganoderma 20 parts, 20 parts, Fructus Mori, Herba Ecliptae 30 parts, Fructus Psoraleae 10 parts, Cacumen Platycladi 35 parts, 20 parts, Folium Pini, Fructus Gleditsia 20 parts, 20 parts, the Radix Rehmanniae, Herba Menthae 15 parts, Fructus Tribuli 20 parts, is ground into coarse powder by after above-mentioned each component mixing, the ethanol that mass fraction is 50 ~ 75% is added according to described coarse powder and ethanol 1:8 (W/V) ratio, soak after 7 days, filter, leave filtrate and medicinal residues respectively; To add distilled water immersion in described medicinal residues after 12 ~ 24 hours, the volume ratio of described medicinal residues and described distilled water is 1:2 ~ 1:4, and temperature fire heating 15 minutes, is cooled to room temperature, filters, obtain filtrate; The filtrate obtained twice is mixed into solution, adjust 5 times that described overall solution volume is described coarse powder volume, and the mass percent making ethanol account for described solution is 10 ~ 20%, then add mantoquita in above-mentioned filtrate, make the concentration of mantoquita in described external medicine composition be 0.02 ~ 0.06g/L.
A kind of hair growth also has the application method of the Chinese medicine composition of black hair function, described oral preparations Chinese medicine composition is brewed 10 ~ 15min through boiling boiled water, brew 8 ~ 10g at every turn, one day twice, after hair washing, described external medicine composition uniform application is also massaged gently in alopecia position and absorb completely to medicine for 5 ~ 10 minutes, each medication 4 ~ 7ml, every day 1 ~ 2 time.Above oral and external application medicine is taken simultaneously, and within 7 days, can control the fuel-displaced and pruritus of scalp, within 10 days, depilation phenomenon obviously reduces, and within 30 days, is a course for the treatment of, hair growth promoting general 1 ~ 3 course for the treatment of, 3 ~ 6 courses for the treatment of of blackening hair.
The clinical experiment of embodiment 4 Chinese medicine composition drug effect of the present invention
The report of typical clinical experiment effect is described below:
Clinical data: the present invention's altogether hair growth with a large amount of poliosis patient 60 example, and with poliosis, man 32 example, female 28 example, the age is 20 ~ 50 years old.
Therapeutic Method: Chinese medicine composition of the present invention is divided into oral preparations and external preparation, oral preparations Chinese medicine composition brews 10 ~ 15min through boiling boiled water, brew 8 ~ 10g at every turn, one day twice, after hair washing, external medicine composition uniform application is also massaged gently in alopecia position and absorb completely to medicine for 5 ~ 10 minutes, each medication 4 ~ 7ml, every day 1 ~ 2 time.
The standard of curative effect evaluation:
Cure: alopecia district natural on-off cycles of hair growth rate reaches more than 80%, and poliosis exists quantity lower than 10%.
Take a turn for the better: alopecia district natural on-off cycles of hair growth rate reaches 20 ~ 80%, and poliosis to there is quantity be 10 ~ 60%.
Do not heal: alopecia district natural on-off cycles of hair growth rate reaches lower than 20%, and poliosis exists quantity higher than 60%.
Therapeutic effect: the common hair growth of the present invention is also routine with a large amount of poliosis patient 60, through 1 ~ 3 course for the treatment of, alopecia district hair hair growth promoting rate all reach more than 80% have 52 example, account for 86.67%, alopecia district natural on-off cycles of hair growth rate reaches 20 ~ 80% 7 examples, account for 11.67%, alopecia district natural on-off cycles of hair growth rate reach lower than 20% only have 1 example, have no any side effect, when through 3 ~ 6 courses for the treatment of, again add up, the blackening hair of patient is obvious, cure 54 examples, take a turn for the better 5 examples, more only there is not 1 example, for seeing any side effect in treatment, cure and followed up a case by regular visits to by 1 year later six months, be showed no recurrence, result shows, therapeutic effect of the present invention is stablized, have no side effect, while hair growth, obviously can reduce poliosis.
Model case:
1, Lee, female, 28 years old, work upward pressure was comparatively large, regularly stayed up late, and cause the serious poliosis of alopecia to increase, use Chinese medicine composition of the present invention after 4 months, cure, poliosis almost be cannot see, and it is glossy that color development recovers black, more than dense.
2, Wang, man, 35 years old, life psychentonia at ordinary times, alopecia was serious, and poliosis is more, and use Chinese medicine composition of the present invention after 5 months, cure, poliosis almost be cannot see, and it is glossy that color development recovers black, more than dense.
3, Zhang, man, 45 years old, alopecia symptom lasting for years, exiguous human hair, presents bareheaded state, abnormal worried, use Chinese medicine composition of the present invention after 3 months, without depilation phenomenon, and start to grow new hair, poliosis reduces, continue to use after 6 months, image is greatly taken on a new look, cure, more than dense, and black has glossy.
Above-mentioned detailed description is the illustrating of possible embodiments for invention, and this embodiment is also not used to limit the scope of the claims of the present invention, does not allly depart from equivalence of the present invention and implements or change, and all should be contained in the scope of the claims of the present invention.
In addition, those skilled in the art also can make various amendments in other form and details, interpolation and replacement in the claims in the present invention scope of disclosure and spirit.Certainly, the changes such as these various amendments made according to the present invention's spirit, interpolation and replacement, all should be included within the present invention's scope required for protection.

Claims (7)

1. a hair growth there is the Chinese medicine composition of black hair function, it is characterized in that, described Chinese medicine composition comprises oral preparations Chinese medicine composition and external medicine composition, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 10 ~ 30 parts, Folium Pini, Herba Ecliptae 10 ~ 30 parts, 10 ~ 30 parts, Fructus Mori, Herba Taraxaci 10 ~ 20 parts, Semen Sesami Nigrum 20 ~ 40 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Radix Salviae Miltiorrhizae 5 ~ 15 parts, 10 ~ 20 parts, Folium Mori, Semen Cassiae 20 ~ 30 parts, Herba Hedyotidis Diffusae 15 ~ 25 parts, Fructus Psoraleae 10 ~ 30 parts, the Radix Astragali 10 ~ 25 parts, Radix Puerariae 10 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 20 parts, 10 ~ 25 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 20 ~ 40 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, 8 ~ 15 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 10 ~ 20 parts, Cacumen Platycladi 15 ~ 25 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 10 ~ 30 parts, Radix Et Rhizoma Rhei 15 ~ 25 parts, 20 ~ 40 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 20 ~ 30 parts, the raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 50 ~ 80 parts, 30 ~ 60 parts, Semen sojae atricolor, Semen Sesami Nigrum 20 ~ 40 parts, the Radix Astragali 10 ~ 30 parts, Ganoderma 10 ~ 20 parts, 20 ~ 30 parts, Fructus Mori, Herba Ecliptae 15 ~ 30 parts, Fructus Psoraleae 10 ~ 30 parts, Cacumen Platycladi 15 ~ 35 parts, 20 ~ 40 parts, Folium Pini, Fructus Gleditsia 10 ~ 20 parts, 20 ~ 30 parts, the Radix Rehmanniae, Herba Menthae 10 ~ 15 parts, Fructus Tribuli 20 ~ 30 parts.
2. a kind of hair growth according to claim 1 there is the Chinese medicine composition of black hair function, it is characterized in that, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 20 parts, Folium Pini, Herba Ecliptae 20 parts, 20 parts, Fructus Mori, Herba Taraxaci 15 parts, Semen Sesami Nigrum 30 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Salviae Miltiorrhizae 10 parts, 12 parts, Folium Mori, Semen Cassiae 25 parts, Herba Hedyotidis Diffusae 20 parts, Fructus Psoraleae 20 parts, the Radix Astragali 15 parts, Radix Puerariae 15 parts, Fructus Ligustri Lucidi 15 parts, 15 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 30 parts, Radix Sophorae Flavescentis 15 parts, 12 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 15 parts, Cacumen Platycladi 20 parts, 12 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 parts, Radix Et Rhizoma Rhei 20 parts, 30 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 25 parts, the raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 65 parts, 45 parts, Semen sojae atricolor, Semen Sesami Nigrum 30 parts, the Radix Astragali 20 parts, Ganoderma 15 parts, 25 parts, Fructus Mori, Herba Ecliptae 25 parts, Fructus Psoraleae 20 parts, Cacumen Platycladi 22 parts, 30 parts, Folium Pini, Fructus Gleditsia 15 parts, 25 parts, the Radix Rehmanniae, Herba Menthae 12 parts, Fructus Tribuli 25 parts.
3. a kind of hair growth according to any one of claim 1 ~ 2 also has the Chinese medicine composition of black hair function, and it is characterized in that, described external medicine composition also comprises solvent and mantoquita.
4. a kind of hair growth according to claim 3 have the Chinese medicine composition of black hair function, it is characterized in that, described solvent is second alcohol and water.
5. a kind of hair growth according to claim 3 have the Chinese medicine composition of black hair function, it is characterized in that, in described external medicine composition, the concentration of mantoquita is 0.02 ~ 0.06g/L.
6. the hair growth described in any one of Claims 1 to 5 also has the preparation method of the Chinese medicine composition of black hair function, it is characterized in that, comprises the following steps:
Step one: prepare oral preparations Chinese medicine composition: the raw material components taking following parts by weight: 10 ~ 30 parts, Folium Pini, Herba Ecliptae 10 ~ 30 parts, 10 ~ 30 parts, Fructus Mori, Herba Taraxaci 10 ~ 20 parts, Semen Sesami Nigrum 20 ~ 40 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Radix Salviae Miltiorrhizae 5 ~ 15 parts, 10 ~ 20 parts, Folium Mori, Semen Cassiae 20 ~ 30 parts, Herba Hedyotidis Diffusae 15 ~ 25 parts, Fructus Psoraleae 10 ~ 30 parts, the Radix Astragali 10 ~ 25 parts, Radix Puerariae 10 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 20 parts, 10 ~ 25 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 20 ~ 40 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, 8 ~ 15 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 10 ~ 20 parts, Cacumen Platycladi 15 ~ 25 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 10 ~ 30 parts, Radix Et Rhizoma Rhei 15 ~ 25 parts, 20 ~ 40 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 20 ~ 30 parts, each component is dry, pulverized 10 ~ 30 mesh sieves, obtain coarse powder, by the described coarse powder mix homogeneously obtained, dry heat sterilization, pack, specification is 8 ~ 10g/ bag,
Step 2: prepare external medicine composition: the raw material components taking following parts by weight: Radix Polygoni Multiflori 50 ~ 80 parts, 30 ~ 60 parts, Semen sojae atricolor, Semen Sesami Nigrum 20 ~ 40 parts, the Radix Astragali 10 ~ 30 parts, Ganoderma 10 ~ 20 parts, 20 ~ 30 parts, Fructus Mori, Herba Ecliptae 15 ~ 30 parts, Fructus Psoraleae 10 ~ 30 parts, Cacumen Platycladi 15 ~ 35 parts, 20 ~ 40 parts, Folium Pini, Fructus Gleditsia 10 ~ 20 parts, 20 ~ 30 parts, the Radix Rehmanniae, Herba Menthae 10 ~ 15 parts, Fructus Tribuli 20 ~ 30 parts, coarse powder is ground into by after above-mentioned each component mixing, the ethanol that mass fraction is 50 ~ 75% is added in=described coarse powder and ethanol 1:8 (W/V) ratio, soak after 7 days, filter, leave filtrate and medicinal residues respectively, to add distilled water immersion in described medicinal residues after 12 ~ 24 hours, temperature fire heating 15 minutes, the volume ratio of described medicinal residues and described distilled water is 1:2 ~ 1:4, is cooled to room temperature, filters, obtains filtrate, the filtrate obtained twice is mixed into solution, adjust 5 times that described overall solution volume is described coarse powder volume, and the mass percent making ethanol account for described solution is 10 ~ 20%, then add mantoquita in above-mentioned filtrate, make the concentration of mantoquita in described external medicine composition be 0.02 ~ 0.06g/L.
7. the hair growth described in an any one of claim 1 ~ 6 also has the application method of the Chinese medicine composition of black hair function, it is characterized in that, described oral preparations Chinese medicine composition is brewed 10 ~ 15min through boiling boiled water, brew 8 ~ 10g at every turn, one day twice, after hair washing, described external medicine composition uniform application is also massaged gently in alopecia position and absorb completely to medicine for 5 ~ 10 minutes, each medication 4 ~ 7ml, every day 1 ~ 2 time.
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