CN104800383A - Traditional Chinese medicine capsule for treating dawn diarrhea and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine capsule for treating dawn diarrhea. The traditional Chinese medicine capsule is prepared from the following raw herbal materials in parts by weight: 10-12 parts of desmodium triquetrum, 12-15 parts of glossogyne tenuifolia, 15-18 parts of blastus cochinchinensis lour, 19-21 parts of eryngium foetidum, 22-25 parts of witchweeds, 15-18 parts of seeds of Chinese dodder, 15-18 parts of gentiana sarcorrhiza, 15-18 parts of snow lotus herbs and 18-22 parts of medicated leaven. A preparation method for the traditional Chinese medicine capsule for treating dawn diarrhea comprises the following steps: a, getting the desmodium triquetrum, the glossogyne tenuifolia, the blastus cochinchinensis lour, the eryngium foetidum, and the witchweeds in parts by weight, and preparing into 400-600-emshed powder to be uniformly mixed; b, getting the seeds of Chinese dodder, the gentiana sarcorrhiza, the snow lotus herbs and the medicated leaven in parts by weight, and preparing into 400-600-meshed powder to be uniformly mixed; c, adding the powder obtained in the step a into a medicinal material dryer, and drying for 30-35 minutes at 110-120 DEG C, and then, cooling; uniformly mixing the powder obtained in the step a with the powder obtained in the step b to obtain a mixture, and filling the mixture into a capsule.

Description

A kind of Chinese medicinal capsule for the treatment of morning diarrhea and preparation method thereof

Technical field

The invention belongs to pharmaceutical formulating art, be specially a kind of Chinese medicinal capsule for the treatment of morning diarrhea and preparation method thereof.

Background technology

" morning diarrhea ", as the term suggests just refer to occur in dawn before, the diarrhoea in division of day and night just before dawn, having another name called morning diarrhea, crow rushes down, is one of common complaint among the elderly.This disease is more common in and is proceeded to period on cool autumn days by the hot summer, and male is more than women.Its cardinal symptom is, when every dawn, around umbilicus, abdominal part pain will occur, and namely borborygmus rush down, and then pacifies after rushing down.This kind of diarrhoea is often for years on end, brings very large worry to patient.

The traditional Chinese medical science is thought, mostly this chronic diarrhea is the one performance of insufficiency of kidney-YANG, so there is the title of " kidney rushes down ".People is to old, and kidney yang deficiency, fire from the gater of life can not warm spleen soil, and namely can not help taste digesting food, digest and assimilate, dysfunction of the spleen in transportation and transformation just there will be has loose bowels.Just before dawn the time-division contain most just when cloudy gas, yang-energy multiple when, under this specific environment, empty person is more empty, thus defines " diarrhea before dawn ".This kind of patient except removing lavatory defecation with being unable to hold oneself back before dawn, the performance of also normal, a series of kidney yang deficiency such as soreness of the waist and knees, spiritlessness and weakness not warm with abdominal part fear of cold, extremity usually.Chinese traditional treatment diarrhea before dawn takes the method for the kidney warming activating the spleen, relieving diarrhea with astringents more, and prescription is commonly used SISHEN WAN and closed cling conditions plus-minus, prescription: Fructus Psoraleae 9 grams, Fructus Schisandrae Chinensis 9 grams, Semen Myristicae (stewing) 9 grams, Fructus Evodiae 5 grams, Radix Aconiti Lateralis Preparata 9 grams, Radix Codonopsis 15 grams, Rhizoma Atractylodis Macrocephalae (parched) 12 grams, the Radix Aucklandiae 6 grams, Halloysitum Rubrum 15 grams, Pericarpium Granati 12 grams, Rhizoma Zingiberis 9 grams, Radix Glycyrrhizae Preparata 6 grams.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicinal capsule for the treatment of morning diarrhea and preparation method thereof.

The present invention treats the Chinese medicinal capsule of morning diarrhea; Be made up of the crude drug of following parts by weight: Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 10 ~ 12 parts, Herba bidentis parviflorae 12 ~ 15 parts, 15 ~ 18 parts, landslide sand, thorn coriander 19 ~ 21 parts, Herba Lobeliae Chinensis 22 ~ 25 parts, Semen Cuscutae 15 ~ 18 parts, money ginseng 15 ~ 18 parts, Herba Saussureae Involueratae 15 ~ 18 parts, six song 18 ~ 22 parts.

As optimization, the Chinese medicinal capsule of this treatment morning diarrhea, be made up of the crude drug of following parts by weight: Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 11 parts, Herba bidentis parviflorae 13 parts, 16 parts, landslide sand, thorn coriander 20 parts, Herba Lobeliae Chinensis 23 parts, Semen Cuscutae 17 parts, money join 17 parts, Herba Saussureae Involueratae 17 parts, six bent 20 parts.

The preparation method of the Chinese medicinal capsule of this treatment morning diarrhea, comprises the following steps:

A, the Herba Desmodii Triquetri (Herba Tadehagi Triquetri) getting described parts by weight, Herba bidentis parviflorae, landslide sand, thorn coriander, Herba Lobeliae Chinensis make 400 ~ 600 object powder mix homogeneously;

B, the Semen Cuscutae getting described parts by weight, money ginseng, Herba Saussureae Involueratae, six songs make 400 ~ 600 object powder mix homogeneously;

C, by the powder in step a, add in medical material dehydrator, dry 30 ~ 35 minutes at 110 ~ 120 DEG C, after cooling; In incapsulating with the powder mix homogeneously in step b.

The present invention treats in the Chinese medicinal capsule prescription of morning diarrhea, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) heat-clearing and toxic substances removing, removing food stagnancy dampness removing, and parasite killing is anticorrosion; For preventing heatstroke, cold, fever, laryngopharynx swelling and pain, nephritis, icterohepatitis, enteritis, bacillary dysentery, infantile malnutrition, vomiting during pregnancy, children's's scleroderma.Herba bidentis parviflorae heat-clearing and toxic substances removing, inducing diuresis and reducing edema, promoting blood circulation by removing blood stasis; For acute tonsillitis, gingivitis, bronchitis, enteritis, urethritis, edema; Herpes zoster is controlled in external, traumatic injury.Landslide sand astringing to arrest bleeding, subduing swelling and detoxicating; Cure mainly puerperal hemorrhage more than, menorrhagia, enteritis, diarrhea.Traumatic injury is controlled in external, traumatic hemorrhage, and skin infection festers.Thorn coriander dispelling wind is antipyretic, stomach invigorating; For flu, measles is caved in, tracheitis, enteritis, diarrhoea, acute infectious hepatitis; Treating swelling and pain by traumatic injury is controlled in external.

Herba Lobeliae Chinensis heat clearing away, removing food stagnancy, for infantile malnutrition, Infantile Summer Fever, infantile diarrhea, icterohepatitis.Semen Cuscutae nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal; For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down.The invigorating the spleen and benefiting QI of money ginseng, tonifying the kidney to consolidate the essence; For body is empty after being ill, infantile malnutrition, cough due to deficiency of the lung, seminal emission, the enuresis, deficiency-heat is not moved back, children's's chronic diarrhea.Herba Saussureae Involueratae kidney invigorating and YANG supporting, regulating menstruation, hemostasis; For snow blindness, toothache, rheumatic arthritis, sexual impotence, menoxenia, metrorrhagia, leucorrhea; Wound hemorrhage is controlled in external.Six songs help digestion, stomach invigorating; For dyspepsia, dyspeptic abdominal distention, diarrhoea.

The present invention treats the Chinese medicinal capsule of morning diarrhea, has effect of heat-clearing and toxic substances removing, promoting blood circulation by removing blood stasis, nourishing the liver and kidney, invigorating the spleen and benefiting QI; Energy enhancing body function, improves intestinal environment; The present invention is made by special process, and multicomponent synergism is obvious, and drug effect is especially outstanding, treats and improves morning diarrhea patients symptomatic successful.

Pertinent clinical data is as follows: physical data: total case 324 example, wherein man 199 example, female 125 example; The oldest 73 years old, minimum 44 years old, average 59 years old; The course of disease is the longest 9 years, the shortest 0.5 year, average 3.7 years.Stochastic averagina is divided into two groups.Two groups of case there was no significant differences (P > 0.05), have comparability.

Diagnostic criteria.To have loose bowels relevant criterion evaluation curative effect in (diarrhea before dawn) diagnostic criteria and " new Chinese medicine guideline of clinical investigations " with reference to kidney yang deficiency syndrome in " Chinese medical disease Standardization of diagnosis and curative effect ".1. had loose bowels before dawn, companion's umbilicus abdomen is had a pain, and namely borborygmus rush down, and rush down lower complete paddy, then pacify after rushing down.2. the course of disease is more than half a year.3., with coldness of the body with chills, soreness of the waist and knees, poor appetite is weak.4. pale tongue with white fur, deep-thready pulse.Exclusion standard 1. auxiliary examination prompts for the diseases such as bacillary dysentery, amebic dysentery, tuberculosis of intestine, colon cancer.2. diabetics, have adverse cardiac patient, scar diathesis person.3. age of sucking or pregnancy women.

Therapeutic Method: two groups of each 162 examples, matched group, adopts Beijing Tongrentang SISHEN WAN, oral, one time 9 grams, 1-2 times on the one, 30 days courses for the treatment of.Treatment group, adopts the capsule in the embodiment of the present invention 1, each serving with 4, and three times on the one, 30 days courses for the treatment of.

Criterion of therapeutical effect: cure: stool is shaped, had a pain in umbilicus week before dawn, borborygmus, the transference cure such as morning diarrhea.Effective: stool is shaped or paste, had a pain in umbilicus week before dawn, borborygmus disappear, occasionally have morning diarrhea.Invalid: to defecate shapeless, before dawn, umbilicus week has a pain, and namely has and rush down meaning, morning diarrhea before borborygmus, and two groups of case efficacy results are in table 1.

Detailed description of the invention

The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; those skilled in the art to nonessential improvement and adjustment more of the present invention, still belong to protection scope of the present invention according to content of the present invention.

Embodiment 1, a, get Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 110 grams, Herba bidentis parviflorae 130 grams, 160 grams, landslide sand, thorn coriander 200 grams, Herba Lobeliae Chinensis 230 restrain into 400 ~ 600 object powder mix homogeneously;

B, get Semen Cuscutae 170 grams, money joins 170 grams, Herba Saussureae Involueratae 170 grams, six songs 200 restrain into 400 ~ 600 object powder mix homogeneously;

C, by the powder in step a, add and permanent step in CT-CI type medical material dehydrator, dry 30 ~ 35 minutes at 110 ~ 120 DEG C, after cooling; With the powder mix homogeneously in step b, in incapsulating according to 0.55 gram one.

Embodiment 2, a, get Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 100 grams, Herba bidentis parviflorae 120 grams, 150 grams, landslide sand, thorn coriander 190 grams, Herba Lobeliae Chinensis 220 restrain into 400 ~ 600 object powder mix homogeneously;

B, get Semen Cuscutae 150 grams, money joins 150 grams, Herba Saussureae Involueratae 150 grams, six songs 180 restrain into 400 ~ 600 object powder mix homogeneously;

C, by the powder in step a, add and permanent step in CT-CI type medical material dehydrator, dry 30 ~ 35 minutes at 110 ~ 120 DEG C, after cooling; With the powder mix homogeneously in step b, in incapsulating according to 0.55 gram one.

Embodiment 3, a, get Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 120 grams, Herba bidentis parviflorae 150 grams, 180 grams, landslide sand, thorn coriander 210 grams, Herba Lobeliae Chinensis 250 restrain into 400 ~ 600 object powder mix homogeneously;

B, get Semen Cuscutae 180 grams, money joins 180 grams, Herba Saussureae Involueratae 180 grams, six songs 220 restrain into 400 ~ 600 object powder mix homogeneously;

C, by the powder in step a, add and permanent step in CT-CI type medical material dehydrator, dry 30 ~ 35 minutes at 110 ~ 120 DEG C, after cooling; With the powder mix homogeneously in step b, in incapsulating according to 0.55 gram one.

Claims (3)

1. treat the Chinese medicinal capsule of morning diarrhea for one kind; It is characterized in that being made up of the crude drug of following weight fraction: Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 10 ~ 12 parts, Herba bidentis parviflorae 12 ~ 15 parts, 15 ~ 18 parts, landslide sand, thorn coriander 19 ~ 21 parts, Herba Lobeliae Chinensis 22 ~ 25 parts, Semen Cuscutae 15 ~ 18 parts, money ginseng 15 ~ 18 parts, Herba Saussureae Involueratae 15 ~ 18 parts, six song 18 ~ 22 parts.

2. the Chinese medicinal capsule for the treatment of morning diarrhea according to claim 1, is characterized in that being made up of the crude drug of following parts by weight: Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 11 parts, Herba bidentis parviflorae 13 parts, 16 parts, landslide sand, thorn coriander 20 parts, Herba Lobeliae Chinensis 23 parts, Semen Cuscutae 17 parts, money join 17 parts, Herba Saussureae Involueratae 17 parts, six bent 20 parts.

3. treat a preparation method for the Chinese medicinal capsule of morning diarrhea described in claim 1, it is characterized in that comprising the following steps:

A, the Herba Desmodii Triquetri (Herba Tadehagi Triquetri) getting described parts by weight, Herba bidentis parviflorae, landslide sand, thorn coriander, Herba Lobeliae Chinensis make 400 ~ 600 object powder mix homogeneously;

B, the Semen Cuscutae getting described parts by weight, money ginseng, Herba Saussureae Involueratae, six songs make 400 ~ 600 object powder mix homogeneously;

C, by the powder in step a, add in medical material dehydrator, dry 30 ~ 35 minutes at 120 ~ 130 DEG C, after cooling; In incapsulating with the powder mix homogeneously in step b.