CN104797240A - 用于立即和延长释放的组合物 - Google Patents

用于立即和延长释放的组合物 Download PDF

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Publication number
CN104797240A
CN104797240A CN201380060349.8A CN201380060349A CN104797240A CN 104797240 A CN104797240 A CN 104797240A CN 201380060349 A CN201380060349 A CN 201380060349A CN 104797240 A CN104797240 A CN 104797240A
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CN
China
Prior art keywords
tolterodine
pharmaceutical composition
active component
compositions according
granule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380060349.8A
Other languages
English (en)
Chinese (zh)
Inventor
瓦林德·阿胡贾
拉詹·维尔马
乌梅什·维纳亚克劳·巴拉巴德
阿尔内·哈格斯滕
克里斯廷·万纳贝里
兰巴布·布鲁谷
阿莫·维拉斯劳·索姆万希
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferring BV
Original Assignee
Ferring BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring BV filed Critical Ferring BV
Publication of CN104797240A publication Critical patent/CN104797240A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201380060349.8A 2012-11-21 2013-11-21 用于立即和延长释放的组合物 Pending CN104797240A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN3575/DEL/2012 2012-11-21
IN3575DE2012 2012-11-21
IN3947/DEL/2012 2012-12-20
IN3947DE2012 2012-12-20
PCT/EP2013/074373 WO2014079922A1 (en) 2012-11-21 2013-11-21 Composition for immediate and extended release

Publications (1)

Publication Number Publication Date
CN104797240A true CN104797240A (zh) 2015-07-22

Family

ID=49619947

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380060349.8A Pending CN104797240A (zh) 2012-11-21 2013-11-21 用于立即和延长释放的组合物

Country Status (18)

Country Link
EP (1) EP2922525A1 (enrdf_load_stackoverflow)
JP (1) JP2016500088A (enrdf_load_stackoverflow)
KR (1) KR20150085826A (enrdf_load_stackoverflow)
CN (1) CN104797240A (enrdf_load_stackoverflow)
AR (1) AR093585A1 (enrdf_load_stackoverflow)
AU (1) AU2013349682A1 (enrdf_load_stackoverflow)
BR (1) BR112015011430A2 (enrdf_load_stackoverflow)
CA (1) CA2891365A1 (enrdf_load_stackoverflow)
EA (1) EA201590805A1 (enrdf_load_stackoverflow)
HK (1) HK1213779A1 (enrdf_load_stackoverflow)
IL (1) IL238648A0 (enrdf_load_stackoverflow)
IN (1) IN2015DN03984A (enrdf_load_stackoverflow)
MX (1) MX2015006399A (enrdf_load_stackoverflow)
PH (1) PH12015501096A1 (enrdf_load_stackoverflow)
SG (2) SG10201703388TA (enrdf_load_stackoverflow)
TW (1) TW201422254A (enrdf_load_stackoverflow)
WO (1) WO2014079922A1 (enrdf_load_stackoverflow)
ZA (1) ZA201503603B (enrdf_load_stackoverflow)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135870A (zh) * 2015-09-01 2018-06-08 韦尔斯利医药有限公司 延缓、延迟和立即释放型制剂及其制造方法和用途
CN108289891A (zh) * 2015-11-23 2018-07-17 韦尔斯利医药有限公司 缓解尿频的组合物,其制造方法和应用
CN108391420A (zh) * 2015-09-30 2018-08-10 韦尔斯利医药有限公司 用于减少排尿频率的组合物及其制备方法和应用
CN108430465A (zh) * 2015-09-30 2018-08-21 韦尔斯利医药有限公司 用于缓解尿频的组合物、其制造方法和用途
CN108601782A (zh) * 2015-12-18 2018-09-28 韦尔斯利医药有限公司 用于缓解尿频的组合物,其制备方法和用途
CN110049757A (zh) * 2017-01-11 2019-07-23 辉凌公司 快速崩解的药物组合物

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AU2014293141A1 (en) 2013-07-23 2016-02-18 Serenity Pharmaceuticals Llc Methods and compositions comprising desmopressin in combination with a beta-3 adrenergic receptor agonist
KR20150144209A (ko) * 2014-06-16 2015-12-24 훼링 비.브이. 안정화된 데스모프레신 또는 이의 약학적으로 허용가능한 염을 함유 약학 조성물
MX2017006655A (es) * 2014-11-20 2018-03-12 Allergan Inc Metodos y composiciones que comprenden desmopresina en combinacion con un antagonista del receptor alfa-adrenergico.
CA2978593A1 (en) 2015-01-12 2016-07-21 Nano Pharmaceutical Laboratories Llc Layered sustained-release microbeads and methods of making the same
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
WO2017182611A1 (en) 2016-04-21 2017-10-26 Valcuria Ab Composition and method for pretreating cancer
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
KR20190021180A (ko) * 2017-08-22 2019-03-05 아주대학교산학협력단 퇴행성 신경질환 치료용 복합 제형 조성물
US12389928B1 (en) * 2024-10-25 2025-08-19 Mccormick & Company, Inc. Flavor-changing product

Citations (3)

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WO2011013082A1 (en) * 2009-07-31 2011-02-03 Ranbaxy Laboratories Limited Multi-layered, multiple unit pharmaceutical compositions
WO2011120903A2 (en) * 2010-03-29 2011-10-06 Ferring B.V. A fast dissolving pharmaceutical composition
CN102245171A (zh) * 2008-11-10 2011-11-16 株式会社爱茉莉太平洋 缓释微粒及其制备方法

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AU4052997A (en) 1996-07-19 1998-02-10 Clarke-Garegg, Margaret A. Levan derivatives, their preparation, composition and applications including medical and food applications
SE9803871D0 (sv) * 1998-11-11 1998-11-11 Pharmacia & Upjohn Ab Therapeutic method and formulation
GB9908014D0 (en) 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
EP1064938A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmaceutical dosage forms for controlled release producing at least a timed pulse
US6509040B1 (en) 2001-06-22 2003-01-21 R.P. Scherer Corporation Fast dispersing dosage forms essentially free of mammalian gelatin
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
BR0309819A (pt) * 2002-05-07 2005-03-01 Ferring Bv Formulações farmacêuticas
US8012505B2 (en) 2003-02-28 2011-09-06 Alk-Abello A/S Dosage form having a saccharide matrix
CN100366294C (zh) 2004-04-30 2008-02-06 量子高科(北京)研究院有限公司 一种口腔速溶制剂及其生产方法
EP1629834A1 (en) 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Sustained release pharmaceutical composition of tolterodine
WO2007029087A2 (en) 2005-09-05 2007-03-15 Ranbaxy Laboratories Limited Controlled release multiple unit formulations
US20090192228A1 (en) 2008-01-28 2009-07-30 Actavis Group Ptc Ehf Controlled-Release Tolterodine Compositions and Methods
EP2552418B1 (en) * 2010-03-29 2017-08-09 Ferring B.V. A fast dissolving pharmaceutical composition
MX356601B (es) * 2010-03-30 2018-05-29 Productos Maver S A De C V Combinación farmacéutica con efecto antimigrañoso, en presentación sólida de liberación diferenciada.
US20120135050A1 (en) * 2010-07-08 2012-05-31 Wellesley Pharmaceuticals, Llc Extended-release formulation for reducing the frequency of urination and method of use thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102245171A (zh) * 2008-11-10 2011-11-16 株式会社爱茉莉太平洋 缓释微粒及其制备方法
WO2011013082A1 (en) * 2009-07-31 2011-02-03 Ranbaxy Laboratories Limited Multi-layered, multiple unit pharmaceutical compositions
WO2011120903A2 (en) * 2010-03-29 2011-10-06 Ferring B.V. A fast dissolving pharmaceutical composition

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135870A (zh) * 2015-09-01 2018-06-08 韦尔斯利医药有限公司 延缓、延迟和立即释放型制剂及其制造方法和用途
CN108391420A (zh) * 2015-09-30 2018-08-10 韦尔斯利医药有限公司 用于减少排尿频率的组合物及其制备方法和应用
CN108430465A (zh) * 2015-09-30 2018-08-21 韦尔斯利医药有限公司 用于缓解尿频的组合物、其制造方法和用途
CN108289891A (zh) * 2015-11-23 2018-07-17 韦尔斯利医药有限公司 缓解尿频的组合物,其制造方法和应用
CN108601782A (zh) * 2015-12-18 2018-09-28 韦尔斯利医药有限公司 用于缓解尿频的组合物,其制备方法和用途
CN110049757A (zh) * 2017-01-11 2019-07-23 辉凌公司 快速崩解的药物组合物

Also Published As

Publication number Publication date
MX2015006399A (es) 2015-07-21
JP2016500088A (ja) 2016-01-07
CA2891365A1 (en) 2014-05-30
WO2014079922A1 (en) 2014-05-30
KR20150085826A (ko) 2015-07-24
PH12015501096A1 (en) 2015-07-27
SG11201503913TA (en) 2015-06-29
EA201590805A1 (ru) 2015-11-30
SG10201703388TA (en) 2017-05-30
EP2922525A1 (en) 2015-09-30
ZA201503603B (en) 2016-01-27
TW201422254A (zh) 2014-06-16
AU2013349682A1 (en) 2015-06-04
AR093585A1 (es) 2015-06-10
BR112015011430A2 (pt) 2017-07-11
IN2015DN03984A (enrdf_load_stackoverflow) 2015-10-02
HK1213779A1 (zh) 2016-07-15
IL238648A0 (en) 2015-06-30

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WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20150722

WD01 Invention patent application deemed withdrawn after publication