CN104790049B - A kind of portable electrostatic spinning equipment and using method thereof - Google Patents
A kind of portable electrostatic spinning equipment and using method thereof Download PDFInfo
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- CN104790049B CN104790049B CN201510214221.3A CN201510214221A CN104790049B CN 104790049 B CN104790049 B CN 104790049B CN 201510214221 A CN201510214221 A CN 201510214221A CN 104790049 B CN104790049 B CN 104790049B
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- shower nozzle
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- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D1/00—Treatment of filament-forming or like material
- D01D1/06—Feeding liquid to the spinning head
- D01D1/09—Control of pressure, temperature or feeding rate
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
- D01D5/0069—Electro-spinning characterised by the electro-spinning apparatus characterised by the spinning section, e.g. capillary tube, protrusion or pin
Abstract
The invention discloses a kind of portable electrostatic spinning equipment and using method thereof, this equipment includes dry battery power, high-voltage electrostatic generator, gas generating unit, spinning injection apparatus；This equipment is with the built-in dry cell of battery compartment as power supply, high-voltage electrostatic generator includes DC high pressure DC inverter and voltage regulating and controlling circuit, dry cell provide voltage through DC high pressure DC inverter boost after as spinning voltage, and combine air-flow auxiliary spining technology, being cased with the airflow duct being connected with gas generating unit outside spinning nozzle, the air current flow direction that gas generating unit imports airflow duct is identical with spinning jet injection direction.The light volume of this equipment quality is little easy to carry, without external power supply not by using environment to be limited during use, can accurately control to adjust spinning parameter simultaneously, easy to use has wide range of applications, and can preferably realize fiber alignment deposition.
Description
Technical field
The present invention relates to a kind of electrospinning device, be specifically related to a kind of small-sized lightweight, portable, accurately determine
To deposition, the electrospinning device of spinning in situ and using method thereof.
Background technology
Method of electrostatic spinning is to prepare one of the simplest efficient method of one-dimensional micro-nanometer fiber, with Conventional nano
Material preparation technology is compared, and has that processing unit (plant) is simple, raw material sources are extensive, spinning is with low cost, can
Scale such as prepares at the advantage, in recent years by widely studied report both domestic and external.Use electrostatic spinning technique
The micro nanometer fiber of processing preparation has high-specific surface area, bigger length/diameter ratio and the physics of uniqueness
The good characteristics such as chemical property, bioengineered tissue, wound dressing, filter protection, medicament slow release,
The fields such as flexible device show great application potential.Method of electrostatic spinning principle is very simple, sketches and is:
Under high voltage electric field effect, polymer solution at spinning nozzle or melt by electrostatic field force effect and
Ejecting, form jet, there is splitting and stretching, simultaneously solvent volatilization in jet in dropping process,
Form micro nanometer fiber curing molding and be deposited on collector.
Conventional electrostatic device for spinning mainly by high voltage power supply, with the spinning solution container of spinning head and fiber
Collecting board three part forms.Be applied at present micro nanometer fiber processing preparation electrostatic spinning apparatus research in
Reveal two kinds of trend: one is the accurate deposition location of fiber；Two is industrialization large-scale production.But,
In actual application, common electrostatic spinning equipment exists that the big quality of volume is the most portable, fiber sinks
The limitations such as long-pending non-directional, seriously constrain the popularization and application of electrostatic spinning technique.In order to solve problem above,
Correlative study worker has carried out many improvement to electrostatic spinning apparatus.Such as Chinese patent " a kind of hand-portable
Formula electrospinning device " tradition spinning nozzle is improved to hand-held and sprays by report in (201220605695.2)
Head pattern, reaches portable, light purpose with this, but this device needs for external power supply, limits
It uses environment, it is impossible to meet the needs of reality application；The reported first such as Long Yunze in 2012 are " a kind of
Portable hand-held electrostatic spinning apparatus " (201210229010.3), this device uses rectangular cell to be high pressure
Direct-flow inverter provide power supply, overcome the defect that existing equipment cannot be carried with so that portable really
It is possibly realized, but this device structure is relatively simple, it is impossible to be accurately controlled regulation spinning parameter so that it is should
With being restricted, meanwhile, this device there is also many deficiencies in terms of the orientated deposition of nanofiber.Cause
This, seek to design a kind of light weight volume little easy to carry, without external power supply, can accurately control to adjust
Joint spinning parameter, be capable of fiber alignment deposition novel electrostatic spinning equipment have a wide range of applications before
Scape and researching value.
Summary of the invention
The technical problem to be solved in the present invention is: provide a kind of portable electrostatic spinning equipment and user thereof
Method, the light volume of this equipment quality is little easy to carry, it is not necessary to external power supply is not by using environment to be limited, permissible
Accurately control to adjust spinning parameter, easy to use have wide range of applications, can preferably realize fiber simultaneously
Orientated deposition.
In order to solve the problems referred to above, the invention provides a kind of portable electrostatic spinning equipment, including dry electricity
Pond power supply, high-voltage electrostatic generator, charging gear, gas generating unit, spinning injection apparatus and absolutely
Edge shell；Described dry battery power electrical connection high-voltage electrostatic generator, charging gear and gas fill
Put；Described high-voltage electrostatic generator includes DC-high pressure DC inverter and voltage regulating and controlling circuit, DC-
The voltage input end electrical connection dry battery power of high pressure DC inverter, the voltage of DC-high pressure DC inverter
Output connects the voltage regulating and controlling circuit controlling high-voltage electrostatic generator output voltage size；Regulating and controlling voltage
The voltage output end of circuit is the voltage output end of high-voltage electrostatic generator, high-voltage electrostatic generator
The minus earth of voltage output end, positive pole connects the metal capillary shower nozzle of spinning injection apparatus, described
Metal capillary shower nozzle connection charging gear；Described spinning injection apparatus also includes and metal capillary shower nozzle
Coaxial airflow duct, described airflow duct is placed on outside metal capillary shower nozzle, and described airflow duct is even
Connect gas generating unit；Described dry battery power, high-voltage electrostatic generator, gas generating unit are placed in
In insulation crust, insulation crust being provided with the opening matched with airflow duct port bore, air-flow is led
Pipe is directed at insulation crust opening part with the injection tip of metal capillary shower nozzle or stretches out from opening part.
This equipment, with conventional DC dry cell as power supply, combines DC-high pressure DC with dry cell inverse simultaneously
Become device and high-pressure electrostatic needed for spinning is provided, it is not necessary to external power supply, solve conventional electrostatic spinning equipment by electricity
Source limits defect, by the output voltage of voltage regulating and controlling circuit regulation DC-high pressure DC inverter, and can be accurate
Controlling high-voltage electrostatic generator and provide the spinning voltage of output, flexible modulation spinning parameter, by introducing
Air-flow auxiliary spinning, can make fiber fixed point orientation accurate deposition.
Further, described gas generating unit includes the gentle pump control circuit of micro air pump；Described miniature
Air pump electrical connection dry battery power and the air pump control circuit of regulation micro air pump gas output size；Described micro-
The outtake tube of type air pump is connected with the airflow duct of spinning injection apparatus, the outtake tube of micro air pump
The flow direction of the air-flow of puff prot ejection is consistent with the spinning jet direction that metal capillary shower nozzle sprays.
The gentle pump control circuit of micro air pump is used to provide the auxiliary of flow velocity controllable precise to guide for spinning process
Air-flow, the air-flow of generation is accelerating jet stretching splitting, while improving spinning efficiency, moreover it is possible to guide electricity
Spin fiber pinpoint at target, orient, accurate deposition in situ, overcome existing portable equipment heavy in orientation
Defect in terms of long-pending, location spinning in situ.
Further, described micro air pump has the outtake tube of multiple connection gas outlet, described in go out conductance
Guan Junyu airflow duct is connected, and the puff prot of outtake tube is symmetrical equal around the axis of metal capillary shower nozzle
Even distribution.
The puff prot of outtake tube is distributed symmetrically and evenly around the axis of metal capillary shower nozzle, its ejection
Air-flow is also uniformly distributed around spinning jet, and the auxiliary produced compared to single puff prot guides air-flow, this
Air flow method evenly, can preferably guide electrospinning fibre to pinpoint at target, orient, the most accurately
Deposition.
Further, described charging gear includes storing the injector syringe of Electrospun precursor liquid, micro wire
Property motor and circuit for controlling motor；The push rod of described micro linear motor and the piston push rod of injector syringe
Coaxial connected, micro linear motor electrical connection dry battery power and the circuit for controlling motor of its rotating speed of control；
The metal capillary shower nozzle of described spinning injection apparatus is the syringe needle matched with injector syringe, described gold
Belong to capillary shower nozzle to be connected on injector syringe.
Use micro linear motor and circuit for controlling motor accurately to control spinning precursor liquid and advance speed, overcome
Mancarried device simple in construction, the uncontrollable defect of spinning parameter so that spinning more controllable precise in the past.
Further, described voltage regulating and controlling circuit, air pump control circuit and circuit for controlling motor are integrated in control
On panel processed, described control panel is provided with DC-high pressure DC inverter power supply switch, regulation DC-
The voltage-regulation knob of high pressure DC inverter output voltage size, micro linear electric power switch, regulation
The propelling rate adaptation knob of micro linear motor speed, micro air pump power switch, regulation micro air pump
The air-flow adjusting knob of gas output and electronic display, described electronic display shows DC-high pressure DC in real time
Inverter output voltage size, micro air pump gas output size and micro linear electric machine rotation drive push rod to push away
The propelling speed size entered, convenient regulation.
Voltage regulating and controlling circuit, air pump control circuit and circuit for controlling motor are integrated on control panel, can
Directly to regulate spinning parameter by the electronic display on control panel and each switching knob, use more square
Just.
Further, described insulation crust includes handle, interior bin and outer bin；Described handle is arranged at
The top of interior bin, interior bin is connected with outer bin；Described dry battery power, high-voltage electrostatic generator,
The micro linear motor of gas generating unit and charging gear is placed in interior bin, the syringe of charging gear
Syringe and spinning injection apparatus are positioned in outer bin, and injector syringe is solid by the draw-in groove arranged in outer bin
It is scheduled in outer bin；The push rod of micro linear motor, the escape pipe of micro air pump and high-pressure electrostatic fill
The voltage output end put stretches out from interior bin, with piston push rod and the spinning of the injector syringe in outer bin
Injection apparatus is connected；Be connected with the interior bin corresponding surface in face of outer bin is provided with and airflow duct port bore
The opening matched, the port of airflow duct and the side edge of this opening, the top of outer bin is provided with
The transparent windows of amount of liquid in observation charging gear.
The design of inside and outside two bins is by the high-voltage electrostatic generator with high-tension electricity, and flimsy gas
Body generating means and charging gear are placed in interior bin, and more safe ready uses and can protect equipment, outward
Bin top is provided with observes the openable transparent windows of amount of liquid in syringe, need to be replaced as often as possible
Or outside the metal capillary shower nozzle of the syringe needle tube and spinning injection apparatus adding Electrospun precursor liquid is placed in
In bin, the Electrospun forerunner's liquid measure in convenient replacement and at any time observation syringe, timely annex solution
Body.
Further, the injection tip of the metal capillary shower nozzle of described spinning injection apparatus is positioned at air-flow and leads
In pipe, the port of described airflow duct is provided with protection cap.
Protection cap can fasten no time, and preferably protection metal capillary shower nozzle, prevents shower nozzle
Pollute.
Further, the output voltage of described high-voltage electrostatic generator is 0～30 kilovolt.
High-voltage electrostatic generator can accurately control to export the spinning voltage of 0～30 kilovolt, this voltage model
Enclose and can meet most of macromolecular material raw materials such as polycaprolactone (PCL), polyvinylpyrrolidone
(PVP), polyurethane (PU), PLA (PLA), polyvinyl alcohol (PVA), polypropylene (PP),
Polyethylene (PE), polyethylene glycol oxide (PEO), gelatin, hyaluronic acid, fibroin albumen, collagen egg
In vain, the spinning electricity of the mixture of one or more materials in the macromolecular material such as sodium alginate, shitosan
Pressure needs, the charging gear guiding in conjunction with air-flow auxiliary and accurately controlling so that the equipment of the present invention has
The scope of application widely.
Present invention also offers the using method of described portable electrostatic spinning equipment: first will prepare
Electrospun precursor liquid add in charging gear, open charging gear, spinning precursor liquid is slowly pushed into be spun
In the metal capillary shower nozzle of silk injection apparatus；Being then turned on gas generating unit switch, gas fills
The gas buying property raw is formed and spinning jet direction air-flow in the same direction after entering airflow duct；Finally confirm height
The minus earth of the voltage output end of pressure electrostatic generator, the power supply opening DC-high pressure DC inverter is opened
Close, by the output voltage of voltage regulating and controlling circuit regulation high-voltage electrostatic generator, metal capillary shower nozzle
The Electrospun precursor liquid drop of ejection end is forming jet under electric field force effect, and jet is made in air-flow auxiliary
Under with, orientated deposition, on target spraying position, i.e. forms micro nanometer fiber film on target spraying position.
The invention has the beneficial effects as follows: the invention provides a kind of portable electrostatic spinning equipment and use thereof
Method, the light volume of this equipment quality is little easy to carry, it is not necessary to external power supply, can not by using environment to be limited
Accurately to control to adjust spinning parameter, easy to use have wide range of applications, can preferably realize fibre simultaneously
Dimension orientated deposition.Specifically:
(1) the DC-high pressure DC inverter that general dry battery is powered replaces conventional electrostatic spinning equipment to use
220 volts of high-voltage DC power supplies powered, have the little light weight of volume, cheap, be easy to carry
Advantage, can carry out spinning whenever and wherever possible in first aid of battle field, the scene of the accident, the most limited by the field, and high
Pressure electrostatic generator can accurately control to export the spinning voltage of 0～30 kilovolt, and this voltage range is permissible
Meet most of macromolecular material raw materials such as polycaprolactone (PCL), polyvinylpyrrolidone (PVP),
Polyurethane (PU), PLA (PLA), polyvinyl alcohol (PVA), polypropylene (PP), poly-second
Alkene (PE), polyethylene glycol oxide (PEO), gelatin, hyaluronic acid, fibroin albumen, collagen,
The spinning voltage of the mixture of one or more materials in the macromolecular material such as sodium alginate, shitosan needs
Want, applied widely.
(2) this equipment combines air-flow auxiliary spinning with electrostatic spinning technique, and the air-flow of generation is accelerating jet
Stretching splitting, improves while spinning efficiency, moreover it is possible to guide electrospinning fibre to pinpoint at target, orient,
Accurate deposition in situ, overcomes existing portable equipment defect in terms of the spinning in situ of orientated deposition, location.
(3) this equipment is easy to operate, and disposable syringe and metal capillary shower nozzle are the most detachable,
Controllability is strong, and spinning parameter (such as the air-flow velocity controlled by micro air pump gas output, is sent out by high-pressure electrostatic
The spinning voltage of generating apparatus output, the Electrospun precursor liquid controlled by micro linear motor push rod propelling speed
Liquid inlet volume) all it is accurately controlled regulation, overcoming existing portable unit simple in construction cannot accurately control to spin
The shortcoming of silk parameter, the performances such as spinning equipment performance is more stable, the shape characteristic of electrospinning fibre are more stable.
In preferred version, voltage regulating and controlling circuit, air pump control circuit and circuit for controlling motor are integrated in chain of command
On plate, can directly regulate spinning parameter by the electronic display on control panel and each switching knob,
Use more convenient.
(4) this device also acts as the electrostatic spraying apparatus of bio-medical material, and air-flow may be guided to be sprayed
Liquid moves along airflow direction, plays orientating function, it is also possible to by weakening ring bag effect and faraday cup
Effect plays constraint effect, thus realizes the accurate spraying of medicine.
Accompanying drawing explanation
The installation diagram of the portable electrostatic spinning equipment of Fig. 1: the present invention；
The top view of the portable electrostatic spinning equipment of Fig. 2: the present invention；
The rearview of the portable electrostatic spinning equipment of Fig. 3: the present invention；
The electrical schematic diagram of the portable electrostatic spinning equipment of Fig. 4: the present invention；
In figure: bin in 1,2 outer bins, 3 transparent windows, 4 injector syringes, 5 metal kernels
Tubule shower nozzle, 6 airflow ducts, 7 micro air pumps, 8 battery compartments, 9DC-high pressure DC inverter, 10 is micro-
Linear motor, 11 control panels, 12 handles, 13 electronic displays, 14 micro linear motor electricity
Source switch, 15 propelling rate adaptation knobs, 16 air-flow adjusting knobs, 17 micro air pump power switches,
18DC-high pressure DC inverter power supply switchs, 19 voltage-regulation knobs.
Detailed description of the invention
For the technical characterstic of this programme can be clearly described, below by embodiment, this programme is illustrated.
Embodiment 1:
As shown in Figures 1 to 3, a kind of portable electrostatic spinning equipment, send out including battery compartment 8, high-pressure electrostatic
Generating apparatus, charging gear, gas generating unit, spinning injection apparatus and insulation crust；Described battery compartment 8
Built-in dry cell electrically connects high-voltage electrostatic generator, charging gear and gas generating unit as power supply；
Described high-voltage electrostatic generator includes DC-high pressure DC inverter 9 and voltage regulating and controlling circuit, DC-high pressure
The voltage input end electrical connection battery compartment 8 of DC inverter 9, the voltage of DC-high pressure DC inverter 9 is defeated
Go out end and connect the voltage regulating and controlling circuit controlling high-voltage electrostatic generator output voltage size；Regulating and controlling voltage electricity
The voltage output end on road is the voltage output end of high-voltage electrostatic generator, high-voltage electrostatic generator
The minus earth of voltage output end, positive pole connects the metal capillary shower nozzle 5 of spinning injection apparatus, described gold
Belong to capillary shower nozzle 5 and connect charging gear；Described spinning injection apparatus also includes and metal capillary shower nozzle 5
Coaxial airflow duct 6, it is outside that described airflow duct 6 is placed on metal capillary shower nozzle 5, and described air-flow is led
Pipe 6 connects gas generating unit；Described battery compartment 8, high-voltage electrostatic generator, gas generating unit are put
In insulation crust, insulation crust is provided with the opening matched with airflow duct 6 port bore, gas
Conduit 6 is directed at insulation crust opening part with the injection tip of metal capillary shower nozzle 5.
Specifically, described gas generating unit includes the gentle pump control circuit of micro air pump 7；Described micro-
Type air pump 7 electrically connects the battery compartment 8 as power supply and the air pump control of regulation micro air pump 7 gas output size
Circuit processed；The outtake tube of described micro air pump 7 is connected with the airflow duct 6 of spinning injection apparatus, micro-
The flow direction of the air-flow of the puff prot ejection of the outtake tube of type air pump 7 sprays with metal capillary shower nozzle 5
The spinning jet direction penetrated is consistent.Described charging gear includes the injector syringe storing Electrospun precursor liquid
4, micro linear motor 10 and circuit for controlling motor；The push rod of described micro linear motor 10 and syringe
The piston push rod of syringe 4 is coaxially connected, and micro linear motor 10 electrically connects battery compartment 8 He as power supply
Control the circuit for controlling motor of its rotating speed；The metal capillary shower nozzle 5 of described spinning injection apparatus is and note
The syringe needle that emitter syringe 4 matches, described metal capillary shower nozzle 5 is connected on injector syringe 4.
Described voltage regulating and controlling circuit, air pump control circuit and circuit for controlling motor are integrated on control panel 11, institute
State and on control panel 11, be provided with DC-high pressure DC inverter power supply switch 18, regulation DC-high pressure DC
The voltage-regulation knob 19 of inverter 9 output voltage size, micro linear electric power switch 14, regulation
The propelling rate adaptation knob 15 of micro linear motor 10 rotating speed, micro air pump power switch 17, regulation
The air-flow adjusting knob 16 of micro air pump 7 gas output and electronic display 13, described electronic display 13
In real time display DC-high pressure DC inverter 9 output voltage size, micro air pump 7 gas output size and miniature
Linear electric machine 10 rotates the propelling speed size driving push rod to advance.Described insulation crust include handle 12,
Interior bin 1 and outer bin 2；Described handle 12 is arranged at the top of interior bin 1, interior bin 1 and Wai Cang
Room 2 is connected；Described battery compartment 8, high-voltage electrostatic generator, gas generating unit and charging gear micro-
Linear motor 10 is placed in interior bin, and injector syringe 4 and the spinning injection apparatus of charging gear are positioned at
In outer bin, injector syringe 4 is fixed in outer bin 2 by the draw-in groove arranged in outer bin 2；Micro-
The voltage output of the push rod of Linear motor 10, the escape pipe of micro air pump 7 and high-voltage electrostatic generator
End stretches out from interior bin 1, with piston push rod and the spinning injection apparatus of the injector syringe 4 in outer bin
It is connected；Be connected with interior bin 1 corresponding surface in face of outer bin 2 is provided with and airflow duct 6 port bore phase
The opening of coupling, the port of airflow duct 6 and the side edge of this opening, the top of outer bin 2 is arranged
Have and observe the openable transparent windows 3 of amount of liquid in charging gear.
In addition, airflow duct 6 can be directed at outside insulation with the injection tip of metal capillary shower nozzle 5
Stretch out from opening part at shell opener.What described micro air pump 7 can have multiple connection gas outlet goes out conductance
Pipe, described outtake tube is all connected with airflow duct 6, and the puff prot of outtake tube sprays around metal capillary
The axis of 5 is symmetrical.The injection tip of the metal capillary shower nozzle 5 of described spinning injection apparatus
May be located in airflow duct 6, the port of airflow duct 6 is provided with protection cap.Described high-pressure electrostatic
The output voltage of generating means is 0～30 kilovolt.
Fig. 4 is the electrical schematic diagram of the portable electrostatic spinning equipment of the present invention, in figure, dry battery power
The electrical connection voltage input end of DC-high pressure DC inverter 9, the voltage input end of micro air pump 7 and micro-
The voltage input end of Linear motor 10 (LINMOT linear electric motors P01-23x80)；DC-high pressure DC
Inverter 9 electrical connection regulates the voltage regulating and controlling circuit of its output voltage size, and (Nidec is straight for micro air pump 7
Flow brushless diaphragm air pump 00H220H020/21/22) electrically connect the air pump control regulating its gas output size
Circuit, micro linear motor 10 electrical connection regulates its push rod and advances the circuit for controlling motor of speed；Described electricity
Pressure circuit for regulating and controlling, air pump control circuit and circuit for controlling motor collectively form control panel 11, regulating and controlling voltage
The voltage output end minus earth of circuit, positive pole connects Metallic Nozzle At The Ingot by wire.
The using method of this novel portable electrospinning device: the Electrospun precursor liquid that first will prepare
Join in the injector syringe 4 of charging gear, open transparent windows 3, injector syringe 4 is fixed
In draw-in groove in the outer bin 2 of insulation crust, open micro linear electric power switch 14, rotate and advance
Rate adaptation knob 15 arranges spinning solution and advances speed, and spinning precursor liquid is slowly pushed into spinning injection apparatus
Metal capillary shower nozzle 5 in；Then opening micro air pump power switch 17, micro air pump 7 produces
Gas is formed and spinning jet direction air-flow in the same direction after the outtake tube of air pump enters airflow duct 6,
Swirling eddy adjusting knob 16 is by regulation micro air pump 7 gas output, the gas stream of regulation airflow duct 6
Speed；Finally confirm the minus earth of the voltage output end of high-voltage electrostatic generator, open DC-high pressure DC
Inverter power supply switch 18, slow rotational voltage adjusting knob 19 arranges the output of high-voltage electrostatic generator
Voltage, the Electrospun precursor liquid drop of metal capillary shower nozzle 5 ejection end is being formed under electric field force effect
Jet, jet is under air-flow booster action, and orientated deposition, on target spraying position, i.e. sprays in target
Micro nanometer fiber film is formed on position.In spinning process, electronic display 13 in real time show propelling speed,
The spinning parameter such as spinning voltage, wind speed, convenient regulation.
Embodiment 2:
Weigh 1.3 grams of polyvinylpyrrolidonepowder powder (PVP, molecular weight 1,300,000), be all dissolved in 8.7
In gram absolute ethyl alcohol, under room temperature, within 2 hours, to being completely dissolved, obtain Solute mass fraction is 13% to magnetic agitation
Uniform PVP Electrospun precursor liquid.
First the PVP Electrospun precursor liquid prepared is joined in injector syringe 4, open transparent sight
Examine window 3, injector syringe 4 is fixed in the draw-in groove in the outer bin 2 of insulation crust, opens micro linear
Electric power switch 14, rotate advance rate adaptation knob 15 arrange spinning solution advance speed be 80 microlitres/
Minute, volume injected is 5 milliliters, and spinning precursor liquid is slowly pushed into the metal capillary of spinning injection apparatus
In pipe shower nozzle 5；Then opening micro air pump power switch 17, the gas that micro air pump 7 produces is through air pump
Outtake tube enter and formed and spinning jet direction air-flow in the same direction after airflow duct 6, swirling eddy is adjusted
Joint knob 16 is 8 liters/min by regulation micro air pump 7 gas output, the gas stream of regulation airflow duct 6
Speed；Finally confirm the minus earth of the voltage output end of high-voltage electrostatic generator, open DC-high pressure DC
Inverter power supply switch 18, slow rotational voltage adjusting knob 19 arranges the output of high-voltage electrostatic generator
Voltage 10 kilovolts, spinning is highly set as 15 centimetres, the Electrospun of metal capillary shower nozzle 5 ejection end
Precursor liquid drop under electric field force effect formed jet, jet under air-flow booster action, orientated deposition
On target spraying position, i.e. forming micro nanometer fiber film on target spraying position, gained fiber is average
A diameter of 556 ± 228 nanometers.
Embodiment 3:
Weigh 2 grams of polycaprolactones (PCL, molecular weight is 45000), be all dissolved in 8 grams of acetone,
Under room temperature, magnetic agitation obtains the uniform PCL that Solute mass fraction is 20% spin to being completely dissolved for 2 hours
Silk precursor liquid.
First the PCL Electrospun precursor liquid prepared is joined in injector syringe 4, open transparent sight
Examine window 3, injector syringe 4 is fixed in the draw-in groove in the outer bin 2 of insulation crust, opens micro linear
Electric power switch 14, rotate propelling rate adaptation knob 15 arranging spinning solution propelling speed is 100 microlitres
/ minute, volume injected is 5 milliliters, and spinning precursor liquid is slowly pushed into the metal capillary of spinning injection apparatus
In pipe shower nozzle 5；Then opening micro air pump power switch 17, the gas that micro air pump 7 produces is through air pump
Outtake tube enter and formed and spinning jet direction air-flow in the same direction after airflow duct 6, swirling eddy is adjusted
Joint knob 16 is 8 liters/min by regulation micro air pump 7 gas output, the gas stream of regulation airflow duct 6
Speed；Finally confirm the minus earth of the voltage output end of high-voltage electrostatic generator, open DC-high pressure DC
Inverter power supply switch 18, slow rotational voltage adjusting knob 19 arranges the output of high-voltage electrostatic generator
Voltage 8 kilovolts, spinning is highly set as 10 centimetres, before the Electrospun of metal capillary shower nozzle 5 ejection end
Driving liquid drop and forming jet under electric field force effect, jet is under air-flow booster action, and orientated deposition exists
On target spraying position, i.e. forming micro nanometer fiber film on target spraying position, gained fiber is the most straight
Footpath is 765 ± 194 nanometers.
The present embodiment uses portable hand-held electrostatic spinning apparatus, prepares nanometer in wound surface electrospinning in situ
Fibre antibacterial dressing, all within the spirit and principles in the present invention, any amendment of being made, equivalent,
Improvement etc. should be included within the scope of the present invention.
Claims (10)
1. a portable electrostatic spinning equipment, it is characterised in that include that dry battery power, high-pressure electrostatic are sent out
Generating apparatus, charging gear, gas generating unit, spinning injection apparatus and insulation crust；Described dry cell electricity
Source electrical connection high-voltage electrostatic generator, charging gear and gas generating unit；Described high-pressure electrostatic fills
Put and include DC-high pressure DC inverter (9) and voltage regulating and controlling circuit, DC-'s high pressure DC inverter (9)
Voltage input end electrical connection dry battery power, the voltage output end of DC-high pressure DC inverter (9) connects control
The voltage regulating and controlling circuit of high-voltage electrostatic generator output voltage size processed；The voltage output of voltage regulating and controlling circuit
End is the voltage output end of high-voltage electrostatic generator, bearing of the voltage output end of high-voltage electrostatic generator
Pole ground connection, positive pole connects the metal capillary shower nozzle (5) of spinning injection apparatus, described metal capillary shower nozzle
(5) connection charging gear；Described spinning injection apparatus also includes coaxial with metal capillary shower nozzle (5)
Airflow duct (6), it is outside that described airflow duct (6) is placed on metal capillary shower nozzle (5), described air-flow
Conduit (6) connects gas generating unit；Described dry battery power, high-voltage electrostatic generator, gas occur
Device is placed in insulation crust, insulation crust is provided with and opening that airflow duct (6) port bore matches
Mouthful, airflow duct (6) be directed at the injection tip of metal capillary shower nozzle (5) insulation crust opening part or
Stretch out from opening part.
2. a kind of portable electrostatic spinning equipment as claimed in claim 1, it is characterised in that described gas
Generating means includes micro air pump (7) gentle pump control circuit；The dry electricity of described micro air pump (7) electrical connection
Pond power supply and the air pump control circuit of regulation micro air pump (7) gas output size；Described micro air pump (7)
Outtake tube be connected with the airflow duct (6) of spinning injection apparatus, the outtake tube of micro air pump (7)
The spinning jet direction one sprayed of flow direction and the metal capillary shower nozzle (5) of air-flow of puff prot ejection
Cause.
3. a kind of portable electrostatic spinning equipment as claimed in claim 2, it is characterised in that described miniature
Air pump (7) has the outtake tube of multiple connection gas outlet, described outtake tube all with airflow duct (6)
Being connected, the puff prot of outtake tube is symmetrical around the axis of metal capillary shower nozzle (5).
4. a kind of portable electrostatic spinning equipment as claimed in claim 2, it is characterised in that described feed
Device includes storing the injector syringe (4) of Electrospun precursor liquid, micro linear motor (10) and motor control
Circuit processed；The push rod of described micro linear motor (10) and the coaxial phase of piston push rod of injector syringe (4)
Even, micro linear motor (10) electrical connection dry battery power and the circuit for controlling motor of its rotating speed of control；Institute
The metal capillary shower nozzle (5) stating spinning injection apparatus is the syringe needle matched with injector syringe (4),
Described metal capillary shower nozzle (5) is connected on injector syringe (4).
5. a kind of portable electrostatic spinning equipment as claimed in claim 4, it is characterised in that described voltage
Circuit for regulating and controlling, air pump control circuit and circuit for controlling motor are integrated on control panel (11), described control
Be provided with DC-high pressure DC inverter power supply switch (18) on panel (11), DC-high pressure DC is inverse in regulation
Become the voltage-regulation knob (19) of device (9) output voltage size, micro linear electric power switch (14),
Regulation propelling rate adaptation knob (15) of micro linear motor (10) rotating speed, micro air pump power switch (17),
The air-flow adjusting knob (16) of regulation micro air pump (7) gas output and electronic display (13), described electricity
Sub-display screen (13) display DC-high pressure DC inverter (9) output voltage size, micro air pump (7) in real time
Gas output size and micro linear motor (10) rotate the propelling speed size driving push rod to advance.
6. a kind of portable electrostatic spinning equipment as claimed in claim 5, it is characterised in that described insulation
Shell includes handle (12), interior bin (1) and outer bin (2)；Described handle (12) is arranged at interior storehouse
The top of room (1), interior bin (1) is connected with outer bin (2)；Described dry battery power, high-pressure electrostatic
The micro linear motor (10) of generating means, gas generating unit and charging gear is placed in interior bin, gives
Injector syringe (4) and the spinning injection apparatus of material device are positioned in outer bin, and injector syringe (4) leads to
The draw-in groove arranged in crossing outer bin (2) is fixed in outer bin (2)；Pushing away of micro linear motor (10)
The voltage output end of bar, the escape pipe of micro air pump (7) and high-voltage electrostatic generator is from interior bin (1)
Stretch out, be connected with piston push rod and the spinning injection apparatus of the injector syringe (4) in outer bin；Outer bin
(2) corresponding surface in face of being connected with interior bin (1) is provided with and matches with airflow duct (6) port bore
Opening, the port of airflow duct (6) and the side edge of this opening, the top of outer bin (2) is provided with
The openable transparent windows (3) of amount of liquid in observation charging gear.
7. a kind of portable electrostatic spinning equipment as claimed in claim 1, it is characterised in that described spinning
The injection tip of the metal capillary shower nozzle (5) of injection apparatus is positioned at airflow duct (6), described air-flow
It is provided with protection cap on the port of conduit (6).
8. a kind of portable electrostatic spinning equipment as claimed in claim 1, it is characterised in that described high pressure
The output voltage of electrostatic generator is 0～30 kilovolt.
The using method of a kind of portable electrostatic spinning equipment the most as claimed in claim 1, it is characterised in that
First the Electrospun precursor liquid prepared is added in charging gear, open charging gear, spinning precursor liquid quilt
It is slowly pushed in the metal capillary shower nozzle (5) of spinning injection apparatus；It is then turned on gas generating unit switch,
The gas that gas generating unit produces enters airflow duct (6) and is formed afterwards and metal capillary shower nozzle (5) spray
The spinning jet direction gone out air-flow in the same direction；Finally confirm voltage output end negative of high-voltage electrostatic generator
Pole ground connection, opens the power switch of DC-high pressure DC inverter (9), by voltage regulating and controlling circuit regulation height
The output voltage of pressure electrostatic generator, the Electrospun precursor liquid drop of metal capillary shower nozzle (5) ejection end
Forming jet under electric field force effect, jet is under air-flow booster action, and orientated deposition is in target spraying portion
On position, i.e. on target spraying position, form micro nanometer fiber film.
The using method of a kind of portable electrostatic spinning equipment the most as claimed in claim 6, it is characterised in that
First the Electrospun precursor liquid prepared is joined in the injector syringe (4) of charging gear, open transparent
Observation window (3), is fixed on injector syringe (4) in the draw-in groove in the outer bin (2) of insulation crust, opens
Open micro linear electric power switch (14), rotate and advance rate adaptation knob (15) that spinning solution propelling is set
Speed, spinning precursor liquid is by the metal capillary shower nozzle (5) being slowly pushed into spinning injection apparatus；Then beat
Opening micro air pump power switch (17), the gas that micro air pump (7) produces enters through the outtake tube of air pump
Airflow duct (6) is formed and spinning jet direction air-flow in the same direction afterwards, and swirling eddy adjusting knob (16) leads to
Overregulate micro air pump (7) gas output, the gas flow rate of regulation airflow duct (6)；Finally confirm high pressure
The minus earth of the voltage output end of electrostatic generator, opens DC-high pressure DC inverter power supply switch
(18), slow rotational voltage adjusting knob (19) arranges the output voltage of high-voltage electrostatic generator, metal
The Electrospun precursor liquid drop of capillary shower nozzle (5) ejection end is forming jet, jet under electric field force effect
Under air-flow booster action, orientated deposition, on target spraying position, is i.e. formed micro-on target spraying position
Nano fibrous membrane.
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010112564A1 (en) * | 2009-04-01 | 2010-10-07 | Centro De Estudios E Investigaciones Técnicas De Gipuzkoa | Template-supported method of forming patterns of nanofibers in the electrospinning process and uses of said nanofibers |
| CN102776583A (en) * | 2012-07-04 | 2012-11-14 | 青岛大学 | Portable handheld electrostatic spinning device |
| CN202968788U (en) * | 2012-11-15 | 2013-06-05 | 西安理工大学 | Handheld portable electrostatic spinning equipment |
| CN203754859U (en) * | 2014-03-21 | 2014-08-06 | 厦门大学 | Handheld type electrostatic spinning device |
| CN104372423A (en) * | 2014-11-28 | 2015-02-25 | 安徽理工大学 | Portable atmosphere glow discharge plasma jet and electrostatic spinning integrated device |
| CN204738056U (en) * | 2015-04-29 | 2015-11-04 | 青岛新智源健康科技有限公司 | Portable electrostatic spinning equipment |
-
2015
- 2015-04-29 CN CN201510214221.3A patent/CN104790049B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010112564A1 (en) * | 2009-04-01 | 2010-10-07 | Centro De Estudios E Investigaciones Técnicas De Gipuzkoa | Template-supported method of forming patterns of nanofibers in the electrospinning process and uses of said nanofibers |
| CN102776583A (en) * | 2012-07-04 | 2012-11-14 | 青岛大学 | Portable handheld electrostatic spinning device |
| CN202968788U (en) * | 2012-11-15 | 2013-06-05 | 西安理工大学 | Handheld portable electrostatic spinning equipment |
| CN203754859U (en) * | 2014-03-21 | 2014-08-06 | 厦门大学 | Handheld type electrostatic spinning device |
| CN104372423A (en) * | 2014-11-28 | 2015-02-25 | 安徽理工大学 | Portable atmosphere glow discharge plasma jet and electrostatic spinning integrated device |
| CN204738056U (en) * | 2015-04-29 | 2015-11-04 | 青岛新智源健康科技有限公司 | Portable electrostatic spinning equipment |
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