CN104758646A - Traditional Chinese medicine composition for treating glaucoma and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating glaucoma and preparation method thereof Download PDFInfo
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- CN104758646A CN104758646A CN201510117107.9A CN201510117107A CN104758646A CN 104758646 A CN104758646 A CN 104758646A CN 201510117107 A CN201510117107 A CN 201510117107A CN 104758646 A CN104758646 A CN 104758646A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating glaucoma and a preparation method thereof, wherein the traditional Chinese medicine composition consists of following components, by mass: 47-58 parts of tribulus terrestris, 5-12 parts of rhizoma anemarrhenae, 3-16 parts of black sesame, 7-16 parts of salviae miltiorrhizae, 26-38 parts of semen cassiae, 8-15 parts of polygala tenuifolia, 19-34 parts of prunella vulgaris, 1-8 parts of radix angelicae, 8-20 parts of gastrodia elata and 25-39 parts of xanthium sibiricum. The preparation method includes following steps: (1) crushing the tribulus terrestris, the rhizoma anemarrhenae, the black sesame, the salviae miltiorrhizae, the semen cassiae, the polygala tenuifolia, the prunella vulgaris, the radix angelicae, the gastrodia elata and the xanthium sibiricum; (2) sieving the crushed components through a sieve in 80-90 meshes; (3) adding water by 5-6 times of the total amount for soaking the crushed components; (4) steam-boiling the soaked components for 60-65 min; and (5) removing the impurities and performing sterilization to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition is good in curative effect, is free of side effect and is free of relapse.
Description
Technical field
The present invention relates to technical field of Chinese medicine, particularly one treats glaucomatous Chinese medicine composition and preparation method thereof.
Background technology
Glaucoma is one of three large diseases causing blindnesses causing the mankind blind, and total crowd's sickness rate is 1%, within 45 years old, is 2% later.Glaucoma causes excavation of optic disc, defect of visual field because intraocular pressure increases, finally can cause blind Severe ophthalmopathy.The intraocular pressure of normal person is 10 ~ 21mmHg (Schitz tonometer), is pathological phenomenon more than 24mmHg.Intraocular pressure increases and can cause visual function damage, and large and dark depression appears in optic disc, and the visual field visible Glaucomatous typical case change.It is more of a specified duration that intraocular pressure increases the persistent period, and visual function damage is more serious.The reason that glaucoma intraocular pressure increases is that the dynamic equilibrium of aqueous humor circulation receives destruction.Minority due to secretion of aqueous humor too much, but most or aqueous humor flows out and there occurs obstacle, as narrow in angle of anterior chamber even closedown, trabecular sclerosis etc.
The main remedy measures of current glaucoma is injection vitamin B, laser therapy, extra-nutrition element, operative treatment, but curative effect is not obvious, can cause damage simultaneously, and easily recur, not easily effect a radical cure liver and heart.
Summary of the invention
The invention provides one and treat glaucomatous Chinese medicine composition and preparation method thereof, said composition, by the synergism of component, enhances therapeutic effect, and has no side effect and also can not recur.
In order to solve the problems of the technologies described above, the technical solution used in the present invention is: one treats glaucomatous Chinese medicine composition, is made up of each component of following mass parts: Fructus Tribuli 47-58 part, Rhizoma Anemarrhenae 5-12 part, Semen Sesami Nigrum 3-16 part, Radix Salviae Miltiorrhizae 7-16 part, Semen Cassiae 26-38 part, Radix Polygalae 8-15 part, Spica Prunellae 19-34 part, Radix Angelicae Dahuricae 1-8 part, Rhizoma Gastrodiae 8-20 part, Herba Xanthii 25-39 part.
Preferably, one treats glaucomatous Chinese medicine composition, is made up of each component of following mass parts: Fructus Tribuli 49-55 part, Rhizoma Anemarrhenae 7-11 part, Semen Sesami Nigrum 5-13 part, Radix Salviae Miltiorrhizae 9-13 part, Semen Cassiae 29-34 part, Radix Polygalae 9-13 part, Spica Prunellae 22-31 part, Radix Angelicae Dahuricae 3-7 part, Rhizoma Gastrodiae 12-18 part, Herba Xanthii 27-32 part.
Preferred, one treats glaucomatous Chinese medicine composition, is made up of each component of following mass parts: Fructus Tribuli 52 parts, the Rhizoma Anemarrhenae 9 parts, Semen Sesami Nigrum 12 parts, Radix Salviae Miltiorrhizae 10 parts, Semen Cassiae 33 parts, Radix Polygalae 12 parts, Spica Prunellae 28 parts, the Radix Angelicae Dahuricae 5 parts, 16 parts, Rhizoma Gastrodiae, Herba Xanthii 29 parts.
A kind of preparation method for the treatment of glaucomatous Chinese medicine composition: according to above-mentioned mass parts, Fructus Tribuli, the Rhizoma Anemarrhenae, Semen Sesami Nigrum, Radix Salviae Miltiorrhizae, Semen Cassiae, Radix Polygalae, Spica Prunellae, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae and Herba Xanthii are pulverized, cross 80-90 mesh sieve, add water to the 5-6 of total amount doubly, steaming and decocting 60-65 minute after soaking, remove impurity, after sterilization, namely obtain described Chinese medicine composition.
Preferably, above-mentioned soak time is 2-3 hour.
Preferably, above-mentioned boiling temperature controls at 90-95 DEG C.
Form each components description of the present invention as follows:
Fructus Tribuli: loose wind, improving eyesight, the therapeutic method to keep the adverse QI flowing downwards, promoting the circulation of blood, controls headache, itching over the body, conjunctival congestion swells nebula, fullness in the chest, cough with dyspnea, lump in the abdomen, newborn difficulty, carbuncle, scrofula.
The Rhizoma Anemarrhenae: gunpowder under genus heat clearing away, cures mainly: epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst, has dividing of " RHIZOMA ANEMARRHENAE with peet " and " unpeeled RHIZOMA ANEMARRHENAE ".
Semen Sesami Nigrum: there is health-care effecies such as " invigorating the liver and kidney, grow the five internal organs, benefiting essence-blood, intestine moistening is dry ", be regarded as nourishing holy product.
Radix Salviae Miltiorrhizae: have stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire, swell and ache for menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.
Semen Cassiae: bitter in the mouth, sweet and cool in nature, have the effects such as clearing away liver-fire, wind-damp dispelling, tonifying kidney and improving eyesight, loosening bowel to relieve constipation, Semen Cassiae is classified as top grade by " legendary god of farming's herbal classic ", and " main optic atrohic blindness, order are excessive, skin is red, tunica albuginea, eye red logical, lacrimation to call it.Clothes benefit of a specified duration is with nothing left, makes light of one's life by commiting suicide ".
Radix Polygalae: the function of have Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, subsiding a swelling, the insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Spica Prunellae: the effect of improving eyesight of relieving inflammation or internal heat, can control conjunctival congestion and swelling pain, headache etc.
The Radix Angelicae Dahuricae: the functions such as the dehumidifying that gets rid of illness, evacuation of pus granulation promoting, promoting blood circulation and stopping pain, cures mainly the diseases such as anemofrigid cold, headache, rhinitis, toothache, leucorrhea with red and white discharge, pain furuncle and phyma poison, also can make spice.
Rhizoma Gastrodiae: endogenous wind stopping, arresting convulsion, controls dizzy pupil, wind syndrome of head headache, numb limbs and tense tendons, hemiplegia, aphasia, pediatric epilepsy scared wind symptom.
Herba Xanthii: " property of medicine opinion " is recorded: " main liver man heat, improving eyesight.”
Beneficial effect: the present invention is by the synergism between component, and make the Chinese medicine composition obtained have good therapeutic effect, total effective rate at 95%-98%, and has no side effect, drug withdrawal also without recurrence, can well be used for clinical treatment after one month.
Detailed description of the invention
Embodiment 1
One treats glaucomatous Chinese medicine composition, is made up of each component of following mass parts: Fructus Tribuli 47 parts, the Rhizoma Anemarrhenae 5 parts, Semen Sesami Nigrum 3 parts, Radix Salviae Miltiorrhizae 7 parts, Semen Cassiae 26 parts, Radix Polygalae 8 parts, Spica Prunellae 19 parts, the Radix Angelicae Dahuricae 1 part, 8 parts, Rhizoma Gastrodiae, Herba Xanthii 25 parts.
Preparation method: according to above-mentioned mass parts, Fructus Tribuli, the Rhizoma Anemarrhenae, Semen Sesami Nigrum, Radix Salviae Miltiorrhizae, Semen Cassiae, Radix Polygalae, Spica Prunellae, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae and Herba Xanthii are pulverized, cross 80-90 mesh sieve, add water to the 5-6 of total amount doubly, soak after 2-3 hour, steaming and decocting 60-65 minute at 90-95 DEG C of temperature, removes impurity, namely obtains described Chinese medicine composition after sterilization.
Embodiment 2
One treats glaucomatous Chinese medicine composition, is made up of each component of following mass parts: Fructus Tribuli 58 parts, the Rhizoma Anemarrhenae 12 parts, Semen Sesami Nigrum 16 parts, Radix Salviae Miltiorrhizae 16 parts, Semen Cassiae 38 parts, Radix Polygalae 15 parts, Spica Prunellae 34 parts, the Radix Angelicae Dahuricae 8 parts, 20 parts, Rhizoma Gastrodiae, Herba Xanthii 39 parts.
Preparation method: according to above-mentioned mass parts, Fructus Tribuli, the Rhizoma Anemarrhenae, Semen Sesami Nigrum, Radix Salviae Miltiorrhizae, Semen Cassiae, Radix Polygalae, Spica Prunellae, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae and Herba Xanthii are pulverized, cross 80-90 mesh sieve, add water to the 5-6 of total amount doubly, soak after 2-3 hour, steaming and decocting 60-65 minute at 90-95 DEG C of temperature, removes impurity, namely obtains described Chinese medicine composition after sterilization.
Embodiment 3
One treats glaucomatous Chinese medicine composition, is made up of each component of following mass parts: Fructus Tribuli 49 parts, the Rhizoma Anemarrhenae 7 parts, Semen Sesami Nigrum 5 parts, Radix Salviae Miltiorrhizae 9 parts, Semen Cassiae 29 parts, Radix Polygalae 9 parts, Spica Prunellae 22 parts, the Radix Angelicae Dahuricae 3 parts, 12 parts, Rhizoma Gastrodiae, Herba Xanthii 27 parts.
Preparation method: according to above-mentioned mass parts, Fructus Tribuli, the Rhizoma Anemarrhenae, Semen Sesami Nigrum, Radix Salviae Miltiorrhizae, Semen Cassiae, Radix Polygalae, Spica Prunellae, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae and Herba Xanthii are pulverized, cross 80-90 mesh sieve, add water to the 5-6 of total amount doubly, soak after 2-3 hour, steaming and decocting 60-65 minute at 90-95 DEG C of temperature, removes impurity, namely obtains described Chinese medicine composition after sterilization.
Embodiment 4
One treats glaucomatous Chinese medicine composition, is made up of each component of following mass parts: Fructus Tribuli 55 parts, the Rhizoma Anemarrhenae 11 parts, Semen Sesami Nigrum 13 parts, Radix Salviae Miltiorrhizae 13 parts, Semen Cassiae 34 parts, Radix Polygalae 13 parts, Spica Prunellae 31 parts, the Radix Angelicae Dahuricae 7 parts, 18 parts, Rhizoma Gastrodiae, Herba Xanthii 32 parts.
Preparation method: according to above-mentioned mass parts, Fructus Tribuli, the Rhizoma Anemarrhenae, Semen Sesami Nigrum, Radix Salviae Miltiorrhizae, Semen Cassiae, Radix Polygalae, Spica Prunellae, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae and Herba Xanthii are pulverized, cross 80-90 mesh sieve, add water to the 5-6 of total amount doubly, soak after 2-3 hour, steaming and decocting 60-65 minute at 90-95 DEG C of temperature, removes impurity, namely obtains described Chinese medicine composition after sterilization.
Embodiment 5
One treats glaucomatous Chinese medicine composition, is made up of each component of following mass parts: Fructus Tribuli 52 parts, the Rhizoma Anemarrhenae 9 parts, Semen Sesami Nigrum 12 parts, Radix Salviae Miltiorrhizae 10 parts, Semen Cassiae 33 parts, Radix Polygalae 12 parts, Spica Prunellae 28 parts, the Radix Angelicae Dahuricae 5 parts, 16 parts, Rhizoma Gastrodiae, Herba Xanthii 29 parts.
Preparation method: according to above-mentioned mass parts, Fructus Tribuli, the Rhizoma Anemarrhenae, Semen Sesami Nigrum, Radix Salviae Miltiorrhizae, Semen Cassiae, Radix Polygalae, Spica Prunellae, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae and Herba Xanthii are pulverized, cross 80-90 mesh sieve, add water to the 5-6 of total amount doubly, soak after 2-3 hour, steaming and decocting 60-65 minute at 90-95 DEG C of temperature, removes impurity, namely obtains described Chinese medicine composition after sterilization.
Clinical effectiveness:
Clinical Stochastic choice 500 glaucoma patients, are divided into 5 groups at random, often organize 100 people, take the Traditional Chinese drug mixture that embodiment 1-5 is obtained, and morning and evening every day is each once, each 15g, and within 10 days, be a course for the treatment of, after two courses for the treatment of, therapeutic effect sees the following form:
| Cure | Symptom alleviates | Invalid | Side effect | Total effective rate % | |
| Embodiment 1 | 89 | 6 | 5 | 0 | 95 |
| Embodiment 2 | 92 | 4 | 4 | 0 | 96 |
| Embodiment 3 | 91 | 5 | 4 | 0 | 96 |
| Embodiment 4 | 93 | 4 | 3 | 0 | 97 |
| Embodiment 5 | 95 | 3 | 2 | 0 | 98 |
The patient cured and symptom alleviates is paid a return visit after one month in drug withdrawal, all without recurrence.
This shows that the Chinese medicine composition that the present invention obtains has good therapeutic effect, total effective rate is at 95%-98%, and all patients are all without finding that there is side effect phenomenon, and drug withdrawal also without recurrence, can well be used for clinical treatment after one month.
Claims (6)
1. the glaucomatous Chinese medicine composition for the treatment of, it is characterized in that, be made up of the component of following mass parts: Fructus Tribuli 47-58 part, Rhizoma Anemarrhenae 5-12 part, Semen Sesami Nigrum 3-16 part, Radix Salviae Miltiorrhizae 7-16 part, Semen Cassiae 26-38 part, Radix Polygalae 8-15 part, Spica Prunellae 19-34 part, Radix Angelicae Dahuricae 1-8 part, Rhizoma Gastrodiae 8-20 part, Herba Xanthii 25-39 part.
2. one according to claim 1 treats glaucomatous Chinese medicine composition, it is characterized in that, be made up of the component of following mass parts: Fructus Tribuli 49-55 part, Rhizoma Anemarrhenae 7-11 part, Semen Sesami Nigrum 5-13 part, Radix Salviae Miltiorrhizae 9-13 part, Semen Cassiae 29-34 part, Radix Polygalae 9-13 part, Spica Prunellae 22-31 part, Radix Angelicae Dahuricae 3-7 part, Rhizoma Gastrodiae 12-18 part, Herba Xanthii 27-32 part.
3. one according to claim 1 treats glaucomatous Chinese medicine composition, it is characterized in that, be made up of the component of following mass parts: Fructus Tribuli 52 parts, the Rhizoma Anemarrhenae 9 parts, Semen Sesami Nigrum 12 parts, Radix Salviae Miltiorrhizae 10 parts, Semen Cassiae 33 parts, Radix Polygalae 12 parts, Spica Prunellae 28 parts, the Radix Angelicae Dahuricae 5 parts, 16 parts, Rhizoma Gastrodiae, Herba Xanthii 29 parts.
4. a kind of preparation method for the treatment of glaucomatous Chinese medicine composition of claims 1 to 3 described in any one, it is characterized in that: according to above-mentioned mass parts, Fructus Tribuli, the Rhizoma Anemarrhenae, Semen Sesami Nigrum, Radix Salviae Miltiorrhizae, Semen Cassiae, Radix Polygalae, Spica Prunellae, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae and Herba Xanthii are pulverized, cross 80-90 mesh sieve, add water to the 5-6 of total amount doubly, steaming and decocting 60-65 minute after soaking, removes impurity, namely obtains described Chinese medicine composition after sterilization.
5. according to a kind of preparation method for the treatment of glaucomatous Chinese medicine composition described in claim 4, it is characterized in that: described soak time is 2-3 hour.
6., according to a kind of preparation method for the treatment of glaucomatous Chinese medicine composition described in claim 4, it is characterized in that: described boiling temperature controls at 90-95 DEG C.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105343580A (en) * | 2015-12-04 | 2016-02-24 | 吴申龙 | Traditional Chinese medicine composition for curing glaucoma and preparation method as well as use thereof |
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| KR20090084439A (en) * | 2008-02-01 | 2009-08-05 | 부경대학교 산학협력단 | A composition comprising extract of sophora flavescens or prenylated flavonoids compounds isolated therefrom preventing or treating diabetic complication |
| CN101648015A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Chinese medicinal composition for treating glaucoma and application thereof |
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- 2015-03-18 CN CN201510117107.9A patent/CN104758646A/en active Pending
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| KR20090084439A (en) * | 2008-02-01 | 2009-08-05 | 부경대학교 산학협력단 | A composition comprising extract of sophora flavescens or prenylated flavonoids compounds isolated therefrom preventing or treating diabetic complication |
| CN101648015A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Chinese medicinal composition for treating glaucoma and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105343580A (en) * | 2015-12-04 | 2016-02-24 | 吴申龙 | Traditional Chinese medicine composition for curing glaucoma and preparation method as well as use thereof |
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