CN104758350A - Refreshing and cool patch and preparation method thereof - Google Patents
Refreshing and cool patch and preparation method thereof Download PDFInfo
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- CN104758350A CN104758350A CN201510108282.1A CN201510108282A CN104758350A CN 104758350 A CN104758350 A CN 104758350A CN 201510108282 A CN201510108282 A CN 201510108282A CN 104758350 A CN104758350 A CN 104758350A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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Abstract
A refreshing and cool patch and a preparation method thereof. The invention discloses the refreshing and cool patch which includes a refreshing and cool patch body. The refreshing and cool patch body is composed of a back lining layer, a high-molecular gel layer and an anti-binding layer. The anti-binding layer is arranged at an upper layer of the high-molecular gel layer. The back lining layer is arranged at a lower layer of the high-molecular gel layer. The high-molecular gel layer includes following components, by weight: 30-32% of a high-molecular gel material, 1-2% of medicinal alcohol being 75% in mass concentration, 1-2% of mint essential oil, 1-1.5% of rosemary essential oil and 1.1-1.2% of chemical additives, wherein the components are added with pure water to 100%. The invention also discloses the preparation method of the refreshing and cool patch. The mint essential oil has a high-efficient temperature-reducing effect and has a mint fragrance which is cool and refreshing and can excite spirit. The rosemary essential oil has a strong shrinkage effect, can tightening loosened skin, and can reduce hyperemia and swelling. The refreshing and cool patch has effects of exciting spirit and refreshing head, alleviating fatigue and improving attention and is long in refreshing durability.
Description
Technical field
The present invention relates to a kind of refreshment Cooling plaster for releasing swelling pain & itch.
The invention still further relates to a kind of preparation method of refreshment Cooling plaster for releasing swelling pain & itch.
Background technology
At present, in daily life, along with the cold and Warm Changes in Northern of solar term throughout the year, forced labour appropriateness, easy heatstroke in summer, youngster operating pressure is large, usually causes headache, dizzy phenomenon, general employing smears menthocamphorate on skin, but menthocamphorate spreads upon on skin, volatile, taste stimulates, particularly for child, hands goes touching, and effect is just so not good.Therefore, the technology being badly in need of a kind of improvement solves this problem existing in prior art.
Summary of the invention
The technical issues that need to address of the present invention are to provide a kind of refreshment Cooling plaster for releasing swelling pain & itch.
The present invention also technical issues that need to address is to provide a kind of preparation method of refreshment Cooling plaster for releasing swelling pain & itch.
The technical solution used in the present invention is:
Refreshment Cooling plaster for releasing swelling pain & itch, comprise refreshment Cooling plaster for releasing swelling pain & itch body, described refreshment Cooling plaster for releasing swelling pain & itch body is made up of backing layer, Macromolecule glue-line and adherent layer, described adherent layer is positioned at the upper strata of Macromolecule glue-line, described backing layer is positioned at the lower floor of Macromolecule glue-line, and the composition of described Macromolecule glue-line is by weight percentage:
Macromolecule glue material 30-32%;
Mass concentration is the medical ethanol 1-2% of 75%;
Peppermint essential oil 1-2%;
Rosemary ethereal oil 1-1.5%;
Chemical addition agent 1.1-1.2%;
Pure water complements to 100%.
Described backing layer is made up of non-woven fabrics, and described adherent layer is made up of polyethylene film.
Described Macromolecule glue material comprises dispersant, binder, wetting agent, emulsifying agent and thickening agent, described dispersant is sorbitol, and described binder is polyvinylpyrrolidone, and described wetting agent is glycerol, emulsifying agent is tween 80, and described thickening agent is sodium polyacrylate.
Described chemical addition agent comprises antiseptic, penetrating agent, pH adjusting agent, first cross-linking agent and multiple cross-linking agent, described antiseptic is that Gloriosa saperba L. is red, and described penetrating agent is azone, and described pH adjusting agent is tartaric acid, described just cross-linking agent is polyvinylpolypyrrolidone, and described multiple cross-linking agent is dihydroxyaluminum aminoacetate.
A kind of preparation method of above-mentioned refreshment Cooling plaster for releasing swelling pain & itch, comprise the following steps: by the dispersant in Macromolecule glue material, binder, wetting agent, emulsifying agent and thickening agent, according to mass percent 0.45%:3-4.5%:25%:0.05%:1.5-2% mix homogeneously, the antiseptic that mass percentage is 0.12% is added again in Macromolecule glue material, the penetrating agent of 0.5-0.6%, the pH adjusting agent of 0.3%, the material of above-mentioned mixing is carried out cross-linked polymeric, control temperature 50-70 DEG C, first cross-linking agent and 0.08% multiple cross-linking agent that mass percentage is 0.1% is added in cross-linked polymeric process, the Peppermint essential oil that mass percentage is 1-2% is added again in cross-linking polymerization process, the rosemary ethereal oil of 1-2%, the mass concentration of 1-2% is the medical ethanol of 75% and the purified water of interpolation surplus, at stirrer for mixing 8-10 minute, the dispersed novel high polymer slow-release material be mixed into containing active component of last above-mentioned material, novel high polymer slow-release material is coated on polyethylene film, make attached preparation, again attached preparation is affixed on non-woven fabrics, refreshment Cooling plaster for releasing swelling pain & itch.
Advantage of the present invention is: Peppermint essential oil has the effect of temperature with high efficiency, mint flavored is clearly cooled off oneself, the mind rouses oneself, rosemary ethereal oil has very strong contraction, tighten lax skin, also can alleviate the situation of hyperemia, swelling, refreshment, fatigue alleviating, raising attention, continue the refrigerant time long.
Detailed description of the invention
Embodiment 1
Refreshment Cooling plaster for releasing swelling pain & itch, comprise refreshment Cooling plaster for releasing swelling pain & itch body, refreshment Cooling plaster for releasing swelling pain & itch body is made up of backing layer, Macromolecule glue-line and adherent layer, and adherent layer is positioned at the upper strata of Macromolecule glue-line, backing layer is positioned at the lower floor of Macromolecule glue-line, and the composition of Macromolecule glue-line is by weight percentage:
Macromolecule glue material 30%;
Mass concentration is the medical ethanol 1% of 75%;
Peppermint essential oil 1%;
Rosemary ethereal oil 1%;
Chemical addition agent 1.1%;
Pure water complements to 100%.
Backing layer is made up of non-woven fabrics, and adherent layer is made up of polyethylene film.
Macromolecule glue material comprises dispersant, binder, wetting agent, emulsifying agent and thickening agent, and dispersant is sorbitol, and binder is polyvinylpyrrolidone, and wetting agent is glycerol, and emulsifying agent is tween 80, and thickening agent is sodium polyacrylate.
Chemical addition agent comprises antiseptic, penetrating agent, pH adjusting agent, first cross-linking agent and multiple cross-linking agent, and antiseptic is that Gloriosa saperba L. is red, and penetrating agent is azone, and described pH adjusting agent is tartaric acid, and first cross-linking agent is polyvinylpolypyrrolidone, and multiple cross-linking agent is dihydroxyaluminum aminoacetate.
A kind of preparation method of above-mentioned refreshment Cooling plaster for releasing swelling pain & itch, comprise the following steps: by the dispersant in Macromolecule glue material, binder, wetting agent, emulsifying agent and thickening agent, according to mass percent 0.45%:3%:25%:0.05%:1.5% mix homogeneously, the antiseptic that mass percentage is 0.12% is added again in Macromolecule glue material, the penetrating agent of 0.5%, the pH adjusting agent of 0.3%, the material of above-mentioned mixing is carried out cross-linked polymeric, control temperature 50 DEG C, first cross-linking agent and 0.08% multiple cross-linking agent that mass percentage is 0.1% is added in cross-linked polymeric process, the Peppermint essential oil that mass percentage is 1% is added again in cross-linking polymerization process, the rosemary ethereal oil of 1%, the mass concentration of 1% is the medical ethanol of 75% and the purified water of interpolation surplus, stirrer for mixing 8 minutes, the dispersed novel high polymer slow-release material be mixed into containing active component of last above-mentioned material, novel high polymer slow-release material is coated on polyethylene film, make attached preparation, again attached preparation is affixed on non-woven fabrics, refreshment Cooling plaster for releasing swelling pain & itch.
Embodiment 2
Refreshment Cooling plaster for releasing swelling pain & itch, comprise refreshment Cooling plaster for releasing swelling pain & itch body, refreshment Cooling plaster for releasing swelling pain & itch body is made up of backing layer, Macromolecule glue-line and adherent layer, and adherent layer is positioned at the upper strata of Macromolecule glue-line, backing layer is positioned at the lower floor of Macromolecule glue-line, and the composition of Macromolecule glue-line is by weight percentage:
Macromolecule glue material 30.5%;
Mass concentration is the medical ethanol 1.2% of 75%;
Peppermint essential oil 1.2%;
Rosemary ethereal oil 1.1%;
Chemical addition agent 1.12%;
Pure water complements to 100%.
Backing layer is made up of non-woven fabrics, and adherent layer is made up of polyethylene film.
Macromolecule glue material comprises dispersant, binder, wetting agent, emulsifying agent and thickening agent, and dispersant is sorbitol, and binder is polyvinylpyrrolidone, and wetting agent is glycerol, and emulsifying agent is tween 80, and described thickening agent is sodium polyacrylate.
Chemical addition agent comprises antiseptic, penetrating agent, pH adjusting agent, first cross-linking agent and multiple cross-linking agent, and antiseptic is that Gloriosa saperba L. is red, and penetrating agent is azone, and pH adjusting agent is tartaric acid, and first cross-linking agent is polyvinylpolypyrrolidone, and multiple cross-linking agent is dihydroxyaluminum aminoacetate.
A kind of preparation method of above-mentioned refreshment Cooling plaster for releasing swelling pain & itch, comprise the following steps: by the dispersant in Macromolecule glue material, binder, wetting agent, emulsifying agent and thickening agent, according to mass percent 0.45%:3.5%:25%:0.05%:1.5% mix homogeneously, the antiseptic that mass percentage is 0.12% is added again in Macromolecule glue material, the penetrating agent of 0.52%, the pH adjusting agent of 0.3%, the material of above-mentioned mixing is carried out cross-linked polymeric, control temperature 55 DEG C, first cross-linking agent and 0.08% multiple cross-linking agent that mass percentage is 0.1% is added in cross-linked polymeric process, the Peppermint essential oil that mass percentage is 1.2% is added again in cross-linking polymerization process, the rosemary ethereal oil of 1.1%, the mass concentration of 1.2% is the medical ethanol of 75% and the purified water of interpolation surplus, stirrer for mixing 8 minutes, the dispersed novel high polymer slow-release material be mixed into containing active component of last above-mentioned material, novel high polymer slow-release material is coated on polyethylene film, make attached preparation, again attached preparation is affixed on non-woven fabrics, refreshment Cooling plaster for releasing swelling pain & itch.
Embodiment 3
Refreshment Cooling plaster for releasing swelling pain & itch, comprise refreshment Cooling plaster for releasing swelling pain & itch body, refreshment Cooling plaster for releasing swelling pain & itch body is made up of backing layer, Macromolecule glue-line and adherent layer, and adherent layer is positioned at the upper strata of Macromolecule glue-line, backing layer is positioned at the lower floor of Macromolecule glue-line, and the composition of Macromolecule glue-line is by weight percentage:
Macromolecule glue material 31%;
Mass concentration is the medical ethanol 1.4% of 75%;
Peppermint essential oil 1.4%;
Rosemary ethereal oil 1.2%;
Chemical addition agent 1.15%;
Pure water complements to 100%.
Backing layer is made up of non-woven fabrics, and adherent layer is made up of polyethylene film.
Macromolecule glue material comprises dispersant, binder, wetting agent, emulsifying agent and thickening agent, and dispersant is sorbitol, and binder is polyvinylpyrrolidone, and wetting agent is glycerol, and emulsifying agent is tween 80, and described thickening agent is sodium polyacrylate.
Chemical addition agent comprises antiseptic, penetrating agent, pH adjusting agent, first cross-linking agent and multiple cross-linking agent, and antiseptic is that Gloriosa saperba L. is red, and penetrating agent is azone, and pH adjusting agent is tartaric acid, and first cross-linking agent is polyvinylpolypyrrolidone, and multiple cross-linking agent is dihydroxyaluminum aminoacetate.
A kind of preparation method of above-mentioned refreshment Cooling plaster for releasing swelling pain & itch, comprise the following steps: by the dispersant in Macromolecule glue material, binder, wetting agent, emulsifying agent and thickening agent, according to mass percent 0.45%:4%:25%:0.05%:1.5% mix homogeneously, the antiseptic that mass percentage is 0.12% is added again in Macromolecule glue material, the penetrating agent of 0.55%, the pH adjusting agent of 0.3%, the material of above-mentioned mixing is carried out cross-linked polymeric, control temperature 60 DEG C, first cross-linking agent and 0.08% multiple cross-linking agent that mass percentage is 0.1% is added in cross-linked polymeric process, the Peppermint essential oil that mass percentage is 1.4% is added again in cross-linking polymerization process, the rosemary ethereal oil of 1.2%, the mass concentration of 1.4% is the medical ethanol of 75% and the purified water of interpolation surplus, stirrer for mixing 9 minutes, the dispersed novel high polymer slow-release material be mixed into containing active component of last above-mentioned material, novel high polymer slow-release material is coated on polyethylene film, make attached preparation, again attached preparation is affixed on non-woven fabrics, refreshment Cooling plaster for releasing swelling pain & itch.
Embodiment 4
Refreshment Cooling plaster for releasing swelling pain & itch, comprise refreshment Cooling plaster for releasing swelling pain & itch body, refreshment Cooling plaster for releasing swelling pain & itch body is made up of backing layer, Macromolecule glue-line and adherent layer, and adherent layer is positioned at the upper strata of Macromolecule glue-line, backing layer is positioned at the lower floor of Macromolecule glue-line, and the composition of Macromolecule glue-line is by weight percentage:
Macromolecule glue material 31.5%;
Mass concentration is the medical ethanol 1.6% of 75%;
Peppermint essential oil 1.6%;
Rosemary ethereal oil 1.3%;
Chemical addition agent 1.18%;
Pure water complements to 100%.
Backing layer is made up of non-woven fabrics, and described adherent layer is made up of polyethylene film.
Macromolecule glue material comprises dispersant, binder, wetting agent, emulsifying agent and thickening agent, and dispersant is sorbitol, and binder is polyvinylpyrrolidone, and wetting agent is glycerol, and emulsifying agent is tween 80, and thickening agent is sodium polyacrylate.
Chemical addition agent comprises antiseptic, penetrating agent, pH adjusting agent, first cross-linking agent and multiple cross-linking agent, and antiseptic is that Gloriosa saperba L. is red, and penetrating agent is azone, and pH adjusting agent is tartaric acid, and first cross-linking agent is polyvinylpolypyrrolidone, and multiple cross-linking agent is dihydroxyaluminum aminoacetate.
A kind of preparation method of above-mentioned refreshment Cooling plaster for releasing swelling pain & itch, comprise the following steps: by the dispersant in Macromolecule glue material, binder, wetting agent, emulsifying agent and thickening agent, according to mass percent 0.45%:4%:25%:0.05%:2% mix homogeneously, the antiseptic that mass percentage is 0.12% is added again in Macromolecule glue material, the penetrating agent of 0.58%, the pH adjusting agent of 0.3%, the material of above-mentioned mixing is carried out cross-linked polymeric, control temperature 56 DEG C, first cross-linking agent and 0.08% multiple cross-linking agent that mass percentage is 0.1% is added in cross-linked polymeric process, the Peppermint essential oil that mass percentage is 1.6% is added again in cross-linking polymerization process, the rosemary ethereal oil of 1.3%, the mass concentration of 1.6% is the medical ethanol of 75% and the purified water of interpolation surplus, stirrer for mixing 9 minutes, the dispersed novel high polymer slow-release material be mixed into containing active component of last above-mentioned material, novel high polymer slow-release material is coated on polyethylene film, make attached preparation, again attached preparation is affixed on non-woven fabrics, refreshment Cooling plaster for releasing swelling pain & itch.
Embodiment 5
Refreshment Cooling plaster for releasing swelling pain & itch, comprise refreshment Cooling plaster for releasing swelling pain & itch body, refreshment Cooling plaster for releasing swelling pain & itch body is made up of backing layer, Macromolecule glue-line and adherent layer, and adherent layer is positioned at the upper strata of Macromolecule glue-line, backing layer is positioned at the lower floor of Macromolecule glue-line, and the composition of Macromolecule glue-line is by weight percentage:
Macromolecule glue material 32%;
Mass concentration is the medical ethanol 1.8% of 75%;
Peppermint essential oil 1.8%;
Rosemary ethereal oil 1.4%;
Chemical addition agent 1.2%;
Pure water complements to 100%.
Backing layer is made up of non-woven fabrics, and described adherent layer is made up of polyethylene film.
Macromolecule glue material comprises dispersant, binder, wetting agent, emulsifying agent and thickening agent, and dispersant is sorbitol, and binder is polyvinylpyrrolidone, and wetting agent is glycerol, and emulsifying agent is tween 80, and thickening agent is polyacrylate.
Chemical addition agent comprises antiseptic, penetrating agent, pH adjusting agent, first cross-linking agent and multiple cross-linking agent, and antiseptic is that Gloriosa saperba L. is red, and penetrating agent is azone, and pH adjusting agent is tartaric acid, and first cross-linking agent is polyvinylpolypyrrolidone, and multiple cross-linking agent is dihydroxyaluminum aminoacetate.
A kind of preparation method of above-mentioned refreshment Cooling plaster for releasing swelling pain & itch, comprise the following steps: by the dispersant in Macromolecule glue material, binder, wetting agent, emulsifying agent and thickening agent, according to mass percent 0.45%:4.5%:25%:0.05%:2% mix homogeneously, the antiseptic that mass percentage is 0.12% is added again in Macromolecule glue material, the penetrating agent of 0.6%, the pH adjusting agent of 0.3%, the material of above-mentioned mixing is carried out cross-linked polymeric, control temperature 68 DEG C, first cross-linking agent and 0.08% multiple cross-linking agent that mass percentage is 0.1% is added in cross-linked polymeric process, the Peppermint essential oil that mass percentage is 1.8% is added again in cross-linking polymerization process, the rosemary ethereal oil of 1.4%, the mass concentration of 1.8% is the medical ethanol of 75% and the purified water of interpolation surplus, stirrer for mixing 10 minutes, the dispersed novel high polymer slow-release material be mixed into containing active component of last above-mentioned material, novel high polymer slow-release material is coated on polyethylene film, make attached preparation, again attached preparation is affixed on non-woven fabrics, refreshment Cooling plaster for releasing swelling pain & itch.
Embodiment 6
Refreshment Cooling plaster for releasing swelling pain & itch, comprise refreshment Cooling plaster for releasing swelling pain & itch body, refreshment Cooling plaster for releasing swelling pain & itch body is made up of backing layer, Macromolecule glue-line and adherent layer, and adherent layer is positioned at the upper strata of Macromolecule glue-line, backing layer is positioned at the lower floor of Macromolecule glue-line, and the composition of Macromolecule glue-line is by weight percentage:
Macromolecule glue material 32%;
Mass concentration is the medical ethanol 2% of 75%;
Peppermint essential oil 2%;
Rosemary ethereal oil 1.5%;
Chemical addition agent 1.2%;
Pure water complements to 100%.
Backing layer is made up of non-woven fabrics, and adherent layer is made up of polyethylene film.
Macromolecule glue material comprises dispersant, binder, wetting agent, emulsifying agent and thickening agent, and dispersant is sorbitol, and binder is polyvinylpyrrolidone, and wetting agent is glycerol, and emulsifying agent is tween 80, and described thickening agent is sodium polyacrylate.
Chemical addition agent comprises antiseptic, penetrating agent, pH adjusting agent, first cross-linking agent and multiple cross-linking agent, and antiseptic is that Gloriosa saperba L. is red, and penetrating agent is azone, and pH adjusting agent is tartaric acid, and first cross-linking agent is polyvinylpolypyrrolidone, and multiple cross-linking agent is dihydroxyaluminum aminoacetate.
A kind of preparation method of above-mentioned refreshment Cooling plaster for releasing swelling pain & itch, comprise the following steps: by the dispersant in Macromolecule glue material, binder, wetting agent, emulsifying agent and thickening agent, according to mass percent 0.45%:4.5%:25%:0.05%:2% mix homogeneously, the antiseptic that mass percentage is 0.12% is added again in Macromolecule glue material, the penetrating agent of 0.6%, the pH adjusting agent of 0.3%, the material of above-mentioned mixing is carried out cross-linked polymeric, control temperature 70 DEG C, first cross-linking agent and 0.08% multiple cross-linking agent that mass percentage is 0.1% is added in cross-linked polymeric process, the Peppermint essential oil that mass percentage is 2% is added again in cross-linking polymerization process, the rosemary ethereal oil of 2%, the mass concentration of 2% is the medical ethanol of 75% and the purified water of interpolation surplus, stirrer for mixing 10 minutes, the dispersed novel high polymer slow-release material be mixed into containing active component of last above-mentioned material, novel high polymer slow-release material is coated on polyethylene film, make attached preparation, again attached preparation is affixed on non-woven fabrics, refreshment Cooling plaster for releasing swelling pain & itch.
Peppermint essential oil has the effect of temperature with high efficiency, and mint flavored is clearly cooled off oneself, and the mind rouses oneself, rosemary ethereal oil has very strong contraction, tightens lax skin, also can alleviate the situation of hyperemia, swelling, refreshment, fatigue alleviating, raising attention, continue the refrigerant time long.
Claims (5)
1. refreshment Cooling plaster for releasing swelling pain & itch, comprise refreshment Cooling plaster for releasing swelling pain & itch body, it is characterized in that: described refreshment Cooling plaster for releasing swelling pain & itch body is made up of backing layer, Macromolecule glue-line and adherent layer, described adherent layer is positioned at the upper strata of Macromolecule glue-line, described backing layer is positioned at the lower floor of Macromolecule glue-line, and the composition of described Macromolecule glue-line is by weight percentage:
Macromolecule glue material 30-32%;
Mass concentration is the medical ethanol 1-2% of 75%;
Peppermint essential oil 1-2%;
Rosemary ethereal oil 1-1.5%;
Chemical addition agent 1.1-1.2%;
Pure water complements to 100%.
2. refreshment Cooling plaster for releasing swelling pain & itch according to claim 1, it is characterized in that: described backing layer is made up of non-woven fabrics, described adherent layer is made up of polyethylene film.
3. refreshment Cooling plaster for releasing swelling pain & itch according to claim 1, it is characterized in that: described Macromolecule glue material comprises dispersant, binder, wetting agent, emulsifying agent and thickening agent, described dispersant is sorbitol, described binder is polyvinylpyrrolidone, described wetting agent is glycerol, emulsifying agent is tween 80, and described thickening agent is sodium polyacrylate.
4. refreshment Cooling plaster for releasing swelling pain & itch according to claim 1, it is characterized in that: described chemical addition agent comprises antiseptic, penetrating agent, pH adjusting agent, first cross-linking agent and multiple cross-linking agent, described antiseptic is that Gloriosa saperba L. is red, described penetrating agent is azone, described pH adjusting agent is tartaric acid, described just cross-linking agent is polyvinylpolypyrrolidone, and described multiple cross-linking agent is dihydroxyaluminum aminoacetate.
5. the preparation method of a refreshment Cooling plaster for releasing swelling pain & itch as claimed in claim 1, it is characterized in that, comprise the following steps: by the dispersant in Macromolecule glue material, binder, wetting agent, emulsifying agent and thickening agent, according to mass percent 0.45%:3-4.5%:25%:0.05%:1.5-2% mix homogeneously, the antiseptic that mass percentage is 0.12% is added again in Macromolecule glue material, the penetrating agent of 0.5-0.6%, the pH adjusting agent of 0.3%, the material of above-mentioned mixing is carried out cross-linked polymeric, control temperature 50-70 DEG C, first cross-linking agent and 0.08% multiple cross-linking agent that mass percentage is 0.1% is added in cross-linked polymeric process, the Peppermint essential oil that mass percentage is 1-2% is added again in cross-linking polymerization process, the rosemary ethereal oil of 1-2%, the mass concentration of 1-2% is the medical ethanol of 75% and the purified water of interpolation surplus, at stirrer for mixing 8-10 minute, the dispersed novel high polymer slow-release material be mixed into containing active component of last above-mentioned material, novel high polymer slow-release material is coated on polyethylene film, make attached preparation, again attached preparation is affixed on non-woven fabrics, refreshment Cooling plaster for releasing swelling pain & itch.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510108282.1A CN104758350A (en) | 2015-03-12 | 2015-03-12 | Refreshing and cool patch and preparation method thereof |
| PCT/CN2015/099077 WO2016141758A1 (en) | 2015-03-12 | 2015-12-25 | Refreshing and cooling patch and preparation method therefor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510108282.1A CN104758350A (en) | 2015-03-12 | 2015-03-12 | Refreshing and cool patch and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN104758350A true CN104758350A (en) | 2015-07-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510108282.1A Pending CN104758350A (en) | 2015-03-12 | 2015-03-12 | Refreshing and cool patch and preparation method thereof |
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| CN (1) | CN104758350A (en) |
| WO (1) | WO2016141758A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016141758A1 (en) * | 2015-03-12 | 2016-09-15 | 施敬东 | Refreshing and cooling patch and preparation method therefor |
| CN111184764A (en) * | 2020-01-14 | 2020-05-22 | 河南农业大学 | Walnut leaf-based essential balm, preparation method thereof and mosquito-repellent incense |
| CN111407799A (en) * | 2020-03-30 | 2020-07-14 | 广东顺德芳香世家天然产品制造有限公司 | Multifunctional essential oil and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113456581B (en) * | 2021-08-09 | 2024-02-02 | 信阳农林学院 | Rosemary essential oil nasal in-situ gel and preparation method and application thereof |
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| CN101843685A (en) * | 2010-05-14 | 2010-09-29 | 东华大学 | BC febrifugal refreshment paste for auxiliary treatment of fever and emergent physical hypothermia and preparation thereof |
| CN103239428A (en) * | 2013-05-27 | 2013-08-14 | 施敬东 | Contraceptive patch and preparation method thereof |
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- 2015-12-25 WO PCT/CN2015/099077 patent/WO2016141758A1/en active Application Filing
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016141758A1 (en) * | 2015-03-12 | 2016-09-15 | 施敬东 | Refreshing and cooling patch and preparation method therefor |
| CN111184764A (en) * | 2020-01-14 | 2020-05-22 | 河南农业大学 | Walnut leaf-based essential balm, preparation method thereof and mosquito-repellent incense |
| CN111407799A (en) * | 2020-03-30 | 2020-07-14 | 广东顺德芳香世家天然产品制造有限公司 | Multifunctional essential oil and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016141758A1 (en) | 2016-09-15 |
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