CN104740618A - Sugar pill for acute glomerulonephritis of children and preparation method of sugar pill - Google Patents

Sugar pill for acute glomerulonephritis of children and preparation method of sugar pill Download PDF

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CN104740618A
CN104740618A CN201510139364.2A CN201510139364A CN104740618A CN 104740618 A CN104740618 A CN 104740618A CN 201510139364 A CN201510139364 A CN 201510139364A CN 104740618 A CN104740618 A CN 104740618A
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sugar pill
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CN104740618B (en
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曹燕欣
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Sun Huatang
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Abstract

The invention discloses a sugar pill for acute glomerulonephritis of children. The sugar pill is prepared from the following main raw materials in parts by weight: 5-15 parts of ginseng, 3-8 parts of liquorice, 5-10 parts of pericarpium citri reticulatae, 2-4 parts of medicated leaven, 4-11 parts of collagen, 8-16 parts of ossein, 7-15 parts of snow pears, 5-15 parts of honeysuckle, 3-7 parts of coix seeds, 6-10 parts of aussurea involucrate seeds, 3-9 parts of fritillaria cirrhosa, 6-9 parts of donkey-hide gelatin, 0.5-1.5 parts of shrimps, 4-8 parts of longan, 3-8 parts of calcium gluconate tablets and 5-10 parts of litchi. The sugar pill has the efficacies of relieving a cough and asthma and moistening the lung; the raw materials are available in medicine source, and low in cost; most of the selected raw materials are materials with mild medicine property; and the economic and physical burden is not increased for users after the sugar pill is used for a long period of time.

Description

Sugar pill of a kind of acute glomerulonephritis of baby and preparation method thereof
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to sugar pill of a kind of acute glomerulonephritis of baby and preparation method thereof.
Background technology
Acute glomerulonephritis of baby is called for short acute nephritis, and refer to that one group of cause of disease differs, clinical manifestation is Acute onset, based on hematuria, accompanies albuminuria in various degree, can have edema, hypertension, or the glomerule illness of the feature such as renal insufficiency.Can be divided into acute poststreptococcal glomerulonephritis (APSGN) and non-post-streptococcal glomerulonephritis, this section acute nephritis mainly refers to ASPGN.Although primary disease has Different types of etiopathogenises, the immune plyability glomerulonephritis caused after the case of the overwhelming majority belongs to the actute infection of A group β Hemolytic streptococcus.After hemolytic streptococcal infection, the incidence rate of nephritis is generally 0% ~ 20%.Nineteen eighty-two 105, whole nation pediatric hospital diseases of urinary system inpatient investigation, anti-" O " the rising person of levels in children with acute glomerular nephritis accounts for 61.2%.China each department all with upper respiratory tract infection or tonsillitis the most common, account for 51%, pyoderma or skin infection take second place and account for 25.8%.Acute pharyngitis (being mainly Hemolytic streptococcus 12 type to infect) afterwards nephritis incidence rate is 10% ~ 15%, after pyoderma and scarlet fever, nephritis person 1% ~ 2% occurs.Except A group β Hemolytic streptococcus, other antibacterials are as viridans streptococci, streptococcus pneumoniae, staphylococcus aureus, Bacillus typhi, hemophilus influenza etc., virus, as Coxsackie virus, echo, enteric cytopathogenic human orphan virus 9 type, Measles virus, mumps virus, hepatitis B virus, cytomegalovirus, Epstein-Barr virus, influenza virus etc., also has plasmodium, mycoplasma pneumoniae, Candida albicans filaricide, ancylostome, schistosomicide, toxoplasma, treponema pallidum, leptospira etc. also can cause acute nephritis.
Clinical manifestation acute nephritis clinical manifestation weight great disparity, the lighter only finds microscopic hematuria completely without clinical symptoms, and severe one can be radical property process, occurs renal insufficiency in a short time.1. forerunner infects 90% case has streptococcic forerunner to infect, based on respiratory tract and skin infection.Forerunner infect after through 1 ~ 3 week asymptomatic intermission Acute onset.Pharyngitis has heating, lymphonodi cervicales large and pharyngeally to ooze out for 6 ~ 12 days (average 10 days) before inducement person's disease more.Skin infection sees disease first 14 ~ 28 days (average 20 days).2. typical performance: often there are general malaise, weak, inappetence, heating, headache, dizziness, cough, out of breath, Nausea and vomiting, stomachache and epistaxis etc. acute stage.(1) case of edema 70% has edema, generally only involves Eyelid and perieyelid, severe one 2 ~ 3 days throughout whole body, in non-pitting.(2) hematuria 50% ~ 70% patient has gross hematuria, continues namely to turn microscopic hematuria in 1 ~ 2 week.(3) albuminuria varying degree.Have 20% can reach nephropathy level.Normal in serious mesangial matrix * on albuminuria patient pathology.(4) hypertension 30% ~ 80% case has blood pressure to increase.(5) hypourocrinia gross hematuria severe patient can with dysuria.3. seriously show: minority infant can occur following serious symptoms in disease early stage (within 2 weeks): (1) serious circulating congestion often occurs in onset one week, and due to water, sodium retention, plasma volume increases and occurs circulating congestion.When nephritis infant occurs that moist rales appears in rapid breathing and pulmonary, the probability of circulating congestion should be watched out for, severe patient can occur dyspnea, orthopnea, distension of jugular vein, hacking cough, tells pink foam expectorant, two fullness of the lung cloth moist rales, cardiac dilatation, even occur gallop rhythm, hepatomegaly and hard, edema aggravation.Minority can occur suddenly, and the state of an illness sharply worsens.(2) hypertensive encephalopathy is due to cerebral vasospasm, causes ischemia, anoxia, vascular permeability increase and cerebral edema occurs.Also someone thinks caused by cerebral vasodilators in recent years.Often occur in disease early stage, after blood pressure rises suddenly, blood pressure is often at 150 ~ 160/100 ~ more than 110mmHg.Annual wool yield meeting main suit severe headache, vomiting, diplopia or transient blind, fainting from fear, going into a coma appears suddenly in severe patient.(3) acute renal insufficiency often betides the disease initial stage, occurs the symptom such as oliguria, urine retention, causes temporary azotemia, electrolyte disturbance and metabolic acidosis, generally continues 3 ~ 5, is no more than 10 days.4. atypical presentation: (1) silent acute nephritis is Subclinical Cases, infant only has microscopic hematuria or only has change of serum C 3 to reduce and without other clinical manifestations.(2) the infant edema, the hypertension that have of the outer symptomatic acute nephritis of kidney is obvious, even has serious circulating congestion and hypertensive encephalopathy, and now urine changes slight or routine urianlysis is normal, but has streptococcus forerunner to infect and blood C3 level obviously reduces.(3) with the acute nephritis minority sick child of nephrotic syndrome performance with acute nephritis onset, but edema and albuminuria are given prominence to, and accompany slight hypercholesterolemia and hypoalbuminemia, and clinical manifestation is like nephrotic syndrome.
Acute glomerulonephritis of baby common on market be mostly hormone medicine, easily stimulation is caused to the brain of new child and stomach, brings misery to children's.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide a kind of sugar pill of acute glomerulonephritis of baby, there is effect of relieving cough and asthma, lung moistening, crude drug source of the present invention is easy to get, with low cost, selected raw material mostly be mild in medicine property and thing, life-time service also can not increase the burden on economy and health to user.
Another object of the present invention is just to provide the preparation method of the sugar pill of above-mentioned acute glomerulonephritis of baby.
Technical scheme of the present invention is:
A sugar pill for acute glomerulonephritis of baby, takes off the primary raw material stating weight proportion and is prepared from: Radix Ginseng 5-15 part, Radix Glycyrrhizae 3-8 part, Pericarpium Citri Reticulatae 5-10 part, Massa Medicata Fermentata 2-4 part, collagen protein 4-11 part, ossein 8-16 part, pear 7-15 part, Flos Lonicerae 5-15 part, Semen Coicis 3-7 part, saponin rice 6-10 part, Bulbus Fritillariae Cirrhosae 3-9 part, Colla Corii Asini 6-9 part, shrimp 0.5-1.5 part, Arillus Longan 4-8 part, calcium gluconate tablet 3-8 part, Fructus Litchi 5-10 part.
A sugar pill for acute glomerulonephritis of baby, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Radix Ginseng 8-13 part, Radix Glycyrrhizae 4-7 part, Pericarpium Citri Reticulatae 6-9 part, Massa Medicata Fermentata 2.5-3.5 part, collagen protein 6-9 part, ossein 10-14 part, pear 9-13 part, Flos Lonicerae 8-13 part, Semen Coicis 4-6 part, saponin rice 7-9 part, Bulbus Fritillariae Cirrhosae 5-7 part, Colla Corii Asini 7-8 part, shrimp 0.8-1.3 part, Arillus Longan 5-7 part, calcium gluconate tablet 4-7 part, Fructus Litchi 6-9 part.
A sugar pill for acute glomerulonephritis of baby, more preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Radix Ginseng 10 parts, 5 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 7 parts, Massa Medicata Fermentata 3 parts, collagen protein 8 parts, ossein 12 parts, pear 11 parts, Flos Lonicerae 10 parts, Semen Coicis 5 parts, saponin rice 8 parts, Bulbus Fritillariae Cirrhosae 6 parts, 7.5 parts, Colla Corii Asini, shrimp 1 part, Arillus Longan 6 parts, calcium gluconate tablet 5.5 parts, Fructus Litchi 7.5 parts.
The preparation method of the sugar pill of above-mentioned acute glomerulonephritis of baby, step is as follows:
(1) fresh Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri Reticulatae and Massa Medicata Fermentata are picked clean impurity, clean and run through, be cut into filament and put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 3-7 day, Cheng Gan, it is stand-by to grind to form smalls;
(2) shrimp is cleaned removal palpus, be layered on uniformly in container, even with cooking wine spray, the stewing 2-4 hour of sealing, dryouied by pot, put into edible oil, the consumption of edible oil is 2-4 times of shrimp consumption, the shrimp of having boiled in a covered pot over a slow fire is dropped into after oily heat, fried 5-15 minute, take out, dry in the air 3-8 minute, grind to form fine powder, cross 80-120 mesh sieve stand-by;
(3) fresh Arillus Longan and Fructus Litchi to be shelled enucleation, be placed in baking box by Arillus Longan and Fructus Litchi, roasting 4-9 minute, it is stand-by to grind to form smalls;
(4) by pear clean, peeling, stripping and slicing, be placed on steaming tray, steam 5-15 minute, be pounded thick paste thing with battle of making dough, be placed in fried dry in hot pot stand-by;
(5) saponin rice and Semen Coicis are added water, big fire decocts to boiling, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 30-50 minute slowly, must stirring repeatedly in the process decocted, and filter, filtrate is for subsequent use;
(6) collagen protein, ossein, Colla Corii Asini and calcium gluconate tablet are dropped in step (5) gained filtrate, intense fire is fried open rear continuous stirring 3-8 minute, turns slow fire boiling, and when filtrate is concentrated into 1/2 of original volume, cease fire, filter, filtrate is for subsequent use;
(7) step (1)-(4) gained smalls and step (6) gained filtrate are mixed, heating, when being heated to 30-40 DEG C, adds Mel, after Mel melts completely, repeatedly rubs, and evenly, be twisted into medicated strip, cutting in bulk, is kneaded into sugar pill, bottles and get final product.。
Above-mentioned preparation method, step (1) is cut into filament puts in food steamer and sprays rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and dries in the air 4-6 day (preferred, to be cut into filament and to put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 5).
Above-mentioned preparation method, step (2) shrimp is cleaned and removes palpus, is layered on uniformly in container, even with cooking wine spray, seals stewing 2.5-3.5 hour (preferred, shrimp is clean removes palpus, is layered on uniformly in container, and even with cooking wine spray, sealing is boiled in a covered pot over a slow fire 3 hours).
Above-mentioned preparation method, the consumption of step (2) edible oil is 2.5-3.5 times of shrimp consumption, drops into the shrimp of having boiled in a covered pot over a slow fire after oily heat, fried 8-13 minute (preferred, the consumption of edible oil is 3 times of shrimp consumption, drops into the shrimp of having boiled in a covered pot over a slow fire after oily heat, explodes 10 minutes).
Above-mentioned preparation method, Arillus Longan and Fructus Litchi are placed in baking box by step (3), roasting 5-8 minute (preferred, Arillus Longan and Fructus Litchi are placed in baking box, roasting 7 minutes).
Above-mentioned preparation method, step (5) drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmer slowly 35-45 minute (preferred, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 40 minutes slowly).
Above-mentioned preparation method, step (6) intense fire is fried open rear continuous stirring 5-7 minute (preferred, intense fire is fried open rear continuous stirring 6 minutes).
Best using method: for making this medicine reach optimum therapeuticing effect, get sugar pill 2-4 grain of the present invention, the morning, noon and afternoon respectively once, 10 days are a course for the treatment of at every turn.
The pharmacological effect of each crude drug is respectively:
Radix Ginseng: weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.For dyspnea with shortness of breath, palpitation and amnesia, thirsty hyperhidrosis, lack of appetite is unable, all acute and chronic diseases and the shock caused after losing blood, collapse.Strongly invigorating primordial QI, promotes the production of body fluid Gu de-, calms the nerves.Control impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, stool lingering diarrhea, and empty cough with asthma is urged, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, and frequent micturition, quenches one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion, and prolonged deficiency is not multiple, the card of all qi-blood-body fluid deficiencies.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, relieving cough, eliminates the phlegm, treatment pharyngalgia laryngitis; Radix Glycyrrhizae or enoxolone have the effect of desoxycortone class, have good effects to chronic adrenocortical hypofunction; Glycyrrhiza preparation can promote stomach mucus to be formed and secretion, extends the epithelial cell life-span, has anti-inflammatory activity, be usually used in the treatment of chronic ulcer and duodenal ulcer; The flavone of Radix Glycyrrhizae has antiinflammatory, spasmolytic and antiacid effect; Radix Glycyrrhizae is also one of primary raw material of rendan mini-pills.
Pericarpium Citri Reticulatae: nature and flavor: bitter in the mouth, pungent, warm in nature.Gui Jing: return lung, spleen channel.Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly for distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Massa Medicata Fermentata: Massa Medicata Fermentata is warm in nature, returns taste warp, has effect of promoting digestion and removing stagnation, invigorating the spleen and regulating the stomach.Be mainly used in retention of food and drink, dyspepsia, distension and fullness in the abdomen, inappetence, vomiting dysentery, and married woman's abdominalgia with blood stasis in puerperal, the diseases such as children's's enlarged abdomen heavily fortified point is long-pending.Massa Medicata Fermentata contains the compositions such as yeast, amylase, ergosterol, volatile oil, fat, protein and vitamin B.Therefore have fabulous dyspepsia and intestinal stasis relieving, stomach function regulating preventing or arresting vomiting, separate and swollenly control dysentery, increase appetite, promote the effects such as metabolism.Can be used for clinically treating chronic gastritis, atrophic gastritis, acute gastroenteritis, amebic dysentery, the various diseases such as abdominal distention, stomachache, diarrhoea and infantile simple dyspepsia, anorexia, food stagnation.
Collagen protein: biopolymer, the main component in animal connective tissue, is also the functional protein that mammal in-vivo content is maximum, distribution is the widest, accounts for 25% ~ 30% of total protein.With the transmission of the formation organized, maturation, cell-tocell, and joint lubrication, wound healing, calcification, blood coagulation and aging etc. have close relationship.Collagen protein is also one of critical raw material of biotech industry most, in all extensive application such as medical material, cosmetics, food industry.
Ossein: the lumbar muscle strain that the work such as the wrist that rheumatoid arthritis, osteoarthritis, dyschondroplasia, sore waist and aching in the waist and the back, prolapse of lumbar intervertebral disc, bursitis of shoulder, tennis elbow, soft tissue injury due to sport, life-time service computer and wrist cause/elbow infringement, clothing factory/restaurant/transport cause; The cramp of osteoporosis, legs and feet, hyperosteogeny, bone are perverse, the dysplasia of teenager skeleton, female menstrual period/puerperal/climacteric bone-loss, carpal bone/femur/ridge vertebra/fracture of the sternum, stature stunt and bow-backed; Pachylosis, fingernail cracking, hair bifurcated, cardiac blood tube wall fragility.
Pear: sweet in the mouth is cold in nature, containing malic acid, citric acid, vitamin B1, B2, C, carotene etc.Effect of pear removing heat-phlegm, is particularly suitable for eating autumn.It is medicinal can control wind heat, lung moistening, the cool heart, expectorant, pathogenic fire reducing, removing toxic substances.
Flos Lonicerae: Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Semen Coicis: nature and flavor: sweet in the mouth, light, cool in nature.Gui Jing: return spleen, stomach, lung meridian.Function: favourable water permeation wets, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, the effect of detoxicating and resolving stagnation of pathogens.Cure mainly: for edema, beriberi, dysuria, diarrhea due to hypofunction of the spleen, arthralgia chiefly caused by damp pathogen contracture, lung abscess, intestinal carbuncle; Wart, cancerous protuberance.
Saponin rice: saponin rice is commonly called as Semen Saussureae Involueratae, saponin rice, Fructus Gleditsia core, Fructus Gleditsia essence, is the fruit of Fructus Gleditsia.Belong to high-energy, Hi CHO, low albumen, low fat food.The effects such as having nourishes heart promotes blood circulation, liver heat removing and eyesight improving, looks improving and the skin nourishing.Having discharges water adds thermal expansion, and colloid is translucent, fragrant glutinous profit mouth, is the precious fully natural green nourishing food of mediation human-body viscera function.
Bulbus Fritillariae Cirrhosae: Bulbus Fritillariae Cirrhosae bitter in the mouth, sweet, cold nature; Return lung, heart channel; Matter profit is let out loose, falls and microlitre; There is removing heat-phlegm, nourishing the lung to arrest cough, effect of mass dissipating and swelling eliminating; Cure mainly asthenia chronic cough, lung-heat type cough, lung abscess vomiting pus, scrofula tuberculosis, acute mastitis, skin ulcer swells.
Colla Corii Asini: Colla Corii Asini, YIN nourishing of enriching blood, moisturizes, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
Shrimp: fresh water shrimp sweet in the mouth warm in nature, tepor, enter liver, kidney channel.The effects such as Macrobrachium nipponensis has kidney invigorating and YANG supporting, and lactogenesis is antitoxin, the controlling nocturnal emission with astringent drugs that nourishes blood, dissolving blood stasis and detoxication, QI invigorating grow sun, removing obstruction in the collateral to relieve pain, appetizing are reduced phlegm.Be suitable for the patients such as impotence due to deficiency of the kidney, seminal emission premature ejaculation, galactostasis, bones and muscles pain, tetany, whole body pruritus, skin ulcer, physical weakness and neurasthenia.Modern medicine study confirms, the high nutritive value of shrimp, can strengthen immunity and the sexual function of human body, kidney invigorating and YANG supporting, premature senescence resistance.
Arillus Longan: Arillus Longan is containing abundant glucose, sucrose and protein etc., and iron-holder is also higher, can promote hemoglobin regeneration, thus reach the effect of enriching blood while raising heat energy, extra-nutrition.Research finds, Arillus Longan is except having benefiting action to whole body, effective especially to brain cell, energy hypermnesis, allaying tiredness.
Calcium gluconate tablet: calcium gluconate tablet, indication is for prevention and therapy calcium deficiency, as osteoporosis, tetany disease, dysosteogenesis, rickets and child, gestation and women breast-feeding their children, menopausal women, the supplementing of old people's calcium.
Fructus Litchi: Fructus Litchi sweet in the mouth, acid, warm in nature, enters the heart, spleen, Liver Channel; Can stop singultus, only diarrhoea, is the dietetic therapy good merchantable brand of intractable singultus and diarrhea before dawn person, has supplementing the brain body-building simultaneously, and appetizing strengthening the spleen, has the effect promoting appetite.
The sugar pill " more holistic " of acute glomerulonephritis of baby of the present invention, both can cure the disease, and can keep fit again to prevent disease, and this is the large feature being different from Drug therapy.And the sugar pill of this acute glomerulonephritis of baby is prepared from according to Chinese medicine principle completely, more safe and reliable, without any side effects.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1a sugar pill for acute glomerulonephritis of baby, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): take off the primary raw material stating weight proportion and be prepared from: Radix Ginseng 5 parts, 3 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 5 parts, Massa Medicata Fermentata 2 parts, collagen protein 4 parts, ossein 8 parts, pear 7 parts, Flos Lonicerae 5 parts, Semen Coicis 3-7 part, saponin rice 6 parts, Bulbus Fritillariae Cirrhosae 3 parts, 6 parts, Colla Corii Asini, shrimp 0.5 part, Arillus Longan 4 parts, calcium gluconate tablet 3 parts, Fructus Litchi 5 parts.
The preparation method of the sugar pill of above-mentioned acute glomerulonephritis of baby, step is as follows:
(1) fresh Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri Reticulatae and Massa Medicata Fermentata are picked clean impurity, clean and run through, be cut into filament and put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 3, Cheng Gan, it is stand-by to grind to form smalls;
(2) shrimp is cleaned removal palpus, be layered on uniformly in container, even with cooking wine spray, stewing 2 hours of sealing, dryouies pot, put into edible oil, the consumption of edible oil is 2 times of shrimp consumption, drops into the shrimp of having boiled in a covered pot over a slow fire, deep fry for five minutes after oily heat, take out, dry in the air 3 minutes, grind to form fine powder, cross 80 mesh sieves stand-by;
(3) fresh Arillus Longan and Fructus Litchi to be shelled enucleation, be placed in baking box by Arillus Longan and Fructus Litchi, roasting 4 minutes, it is stand-by to grind to form smalls;
(4) by pear clean, peeling, stripping and slicing, be placed on steaming tray, steam 5 minutes, be pounded thick paste thing with battle of making dough, be placed in fried dry in hot pot stand-by;
(5) saponin rice and Semen Coicis are added water, big fire decocts to boiling, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 30 minutes slowly, must stirring repeatedly in the process decocted, and filter, filtrate is for subsequent use;
(6) collagen protein, ossein, Colla Corii Asini and calcium gluconate tablet are dropped in step (5) gained filtrate, intense fire is fried open rear continuous stirring 3 minutes, turns slow fire boiling, and when filtrate is concentrated into 1/2 of original volume, cease fire, filter, filtrate is for subsequent use;
(7) step (1)-(4) gained smalls and step (6) gained filtrate are mixed, heating, when being heated to 30 DEG C, adds Mel, after Mel melts completely, repeatedly rubs, and evenly, be twisted into medicated strip, cutting in bulk, is kneaded into sugar pill, bottles and get final product.。
embodiment 2a sugar pill for acute glomerulonephritis of baby, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): take off the primary raw material stating weight proportion and be prepared from: Radix Ginseng 15 parts, 8 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 10 parts, Massa Medicata Fermentata 4 parts, collagen protein 11 parts, ossein 16 parts, pear 15 parts, Flos Lonicerae 15 parts, Semen Coicis 7 parts, saponin rice 10 parts, Bulbus Fritillariae Cirrhosae 9 parts, 9 parts, Colla Corii Asini, shrimp 1.5 parts, Arillus Longan 8 parts, calcium gluconate tablet 8 parts, Fructus Litchi 10 parts.
The preparation method of the sugar pill of above-mentioned acute glomerulonephritis of baby, step is as follows:
(1) fresh Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri Reticulatae and Massa Medicata Fermentata are picked clean impurity, clean and run through, be cut into filament and put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 7, Cheng Gan, it is stand-by to grind to form smalls;
(2) shrimp is cleaned removal palpus, be layered on uniformly in container, even with cooking wine spray, stewing 4 hours of sealing, dryouies pot, put into edible oil, the consumption of edible oil is 4 times of shrimp consumption, drops into the shrimp of having boiled in a covered pot over a slow fire after oily heat, fried 15 minutes, take out, dry in the air 3-8 minute, grinds to form fine powder, crosses 120 mesh sieves stand-by;
(3) fresh Arillus Longan and Fructus Litchi to be shelled enucleation, be placed in baking box by Arillus Longan and Fructus Litchi, roasting 9 minutes, it is stand-by to grind to form smalls;
(4) by pear clean, peeling, stripping and slicing, be placed on steaming tray, steam 15 minutes, be pounded thick paste thing with battle of making dough, be placed in fried dry in hot pot stand-by;
(5) saponin rice and Semen Coicis are added water, big fire decocts to boiling, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 50 minutes slowly, must stirring repeatedly in the process decocted, and filter, filtrate is for subsequent use;
(6) collagen protein, ossein, Colla Corii Asini and calcium gluconate tablet are dropped in step (5) gained filtrate, intense fire is fried open rear continuous stirring 8 minutes, turns slow fire boiling, and when filtrate is concentrated into 1/2 of original volume, cease fire, filter, filtrate is for subsequent use;
(7) step (1)-(4) gained smalls and step (6) gained filtrate are mixed, heating, when being heated to 40 DEG C, adds Mel, after Mel melts completely, repeatedly rubs, and evenly, be twisted into medicated strip, cutting in bulk, is kneaded into sugar pill, bottles and get final product.。
embodiment 3a sugar pill for acute glomerulonephritis of baby, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Ginseng 8 parts, 4 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 6 parts, Massa Medicata Fermentata 2.5 parts, collagen protein 6 parts, ossein 10 parts, pear 9 parts, Flos Lonicerae 8 parts, Semen Coicis 4 parts, saponin rice 7 parts, Bulbus Fritillariae Cirrhosae 5 parts, 7 parts, Colla Corii Asini, shrimp 0.8 part, Arillus Longan 5 parts, calcium gluconate tablet 4 parts, Fructus Litchi 6 parts.
The preparation method of the sugar pill of above-mentioned acute glomerulonephritis of baby, step is as follows:
(1) fresh Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri Reticulatae and Massa Medicata Fermentata are picked clean impurity, clean and run through, be cut into filament and put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 4, Cheng Gan, it is stand-by to grind to form smalls;
(2) shrimp is cleaned removal palpus, be layered on uniformly in container, even with cooking wine spray, stewing 2.5 hours of sealing, dryouies pot, put into edible oil, the consumption of edible oil is 2.5 times of shrimp consumption, drops into the shrimp of having boiled in a covered pot over a slow fire after oily heat, fried 8 minutes, take out, dry in the air 4 minutes, grind to form fine powder, cross 90 mesh sieves stand-by;
(3) fresh Arillus Longan and Fructus Litchi to be shelled enucleation, be placed in baking box by Arillus Longan and Fructus Litchi, roasting 5 minutes, it is stand-by to grind to form smalls;
(4) by pear clean, peeling, stripping and slicing, be placed on steaming tray, steam 8 minutes, be pounded thick paste thing with battle of making dough, be placed in fried dry in hot pot stand-by;
(5) saponin rice and Semen Coicis are added water, big fire decocts to boiling, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 35 minutes slowly, must stirring repeatedly in the process decocted, and filter, filtrate is for subsequent use;
(6) collagen protein, ossein, Colla Corii Asini and calcium gluconate tablet are dropped in step (5) gained filtrate, intense fire is fried open rear continuous stirring 5 minutes, turns slow fire boiling, and when filtrate is concentrated into 1/2 of original volume, cease fire, filter, filtrate is for subsequent use;
(7) step (1)-(4) gained smalls and step (6) gained filtrate are mixed, heating, when being heated to 33 DEG C, adds Mel, after Mel melts completely, repeatedly rubs, and evenly, be twisted into medicated strip, cutting in bulk, is kneaded into sugar pill, bottles and get final product.。
embodiment 4a sugar pill for acute glomerulonephritis of baby, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Ginseng 13 parts, 7 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 9 parts, Massa Medicata Fermentata 3.5 parts, collagen protein 9 parts, ossein 14 parts, pear 13 parts, Flos Lonicerae 13 parts, Semen Coicis 6 parts, saponin rice 9 parts, Bulbus Fritillariae Cirrhosae 7 parts, 8 parts, Colla Corii Asini, shrimp 1.3 parts, Arillus Longan 7 parts, calcium gluconate tablet 7 parts, Fructus Litchi 9 parts.
The preparation method of the sugar pill of above-mentioned acute glomerulonephritis of baby, step is as follows:
(1) fresh Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri Reticulatae and Massa Medicata Fermentata are picked clean impurity, clean and run through, be cut into filament and put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 6, Cheng Gan, it is stand-by to grind to form smalls;
(2) shrimp is cleaned removal palpus, be layered on uniformly in container, even with cooking wine spray, stewing 3.5 hours of sealing, dryouies pot, put into edible oil, the consumption of edible oil is 3.5 times of shrimp consumption, drops into the shrimp of having boiled in a covered pot over a slow fire after oily heat, fried 13 minutes, take out, dry in the air 7 minutes, grind to form fine powder, cross 110 mesh sieves stand-by;
(3) fresh Arillus Longan and Fructus Litchi to be shelled enucleation, be placed in baking box by Arillus Longan and Fructus Litchi, roasting 8 minutes, it is stand-by to grind to form smalls;
(4) by pear clean, peeling, stripping and slicing, be placed on steaming tray, steam 13 minutes, be pounded thick paste thing with battle of making dough, be placed in fried dry in hot pot stand-by;
(5) saponin rice and Semen Coicis are added water, big fire decocts to boiling, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 45 minutes slowly, must stirring repeatedly in the process decocted, and filter, filtrate is for subsequent use;
(6) collagen protein, ossein, Colla Corii Asini and calcium gluconate tablet are dropped in step (5) gained filtrate, intense fire is fried open rear continuous stirring 7 minutes, turns slow fire boiling, and when filtrate is concentrated into 1/2 of original volume, cease fire, filter, filtrate is for subsequent use;
(7) step (1)-(4) gained smalls and step (6) gained filtrate are mixed, heating, when being heated to 38 DEG C, adds Mel, after Mel melts completely, repeatedly rubs, and evenly, be twisted into medicated strip, cutting in bulk, is kneaded into sugar pill, bottles and get final product.。
embodiment 5a sugar pill for acute glomerulonephritis of baby, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Ginseng 10 parts, 5 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 7 parts, Massa Medicata Fermentata 3 parts, collagen protein 8 parts, ossein 12 parts, pear 11 parts, Flos Lonicerae 10 parts, Semen Coicis 5 parts, saponin rice 8 parts, Bulbus Fritillariae Cirrhosae 6 parts, 7.5 parts, Colla Corii Asini, shrimp 1 part, Arillus Longan 6 parts, calcium gluconate tablet 5.5 parts, Fructus Litchi 7.5 parts.
The preparation method of the sugar pill of above-mentioned acute glomerulonephritis of baby, step is as follows:
(1) fresh Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri Reticulatae and Massa Medicata Fermentata are picked clean impurity, clean and run through, be cut into filament and put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 5, Cheng Gan, it is stand-by to grind to form smalls;
(2) shrimp is cleaned removal palpus, be layered on uniformly in container, even with cooking wine spray, stewing 3 hours of sealing, dryouies pot, put into edible oil, the consumption of edible oil is 3 times of shrimp consumption, drops into the shrimp of having boiled in a covered pot over a slow fire after oily heat, fried 10 minutes, take out, dry in the air 6 minutes, grind to form fine powder, cross 100 mesh sieves stand-by;
(3) fresh Arillus Longan and Fructus Litchi to be shelled enucleation, be placed in baking box by Arillus Longan and Fructus Litchi, roasting 7 minutes, it is stand-by to grind to form smalls;
(4) by pear clean, peeling, stripping and slicing, be placed on steaming tray, steam 10 minutes, be pounded thick paste thing with battle of making dough, be placed in fried dry in hot pot stand-by;
(5) saponin rice and Semen Coicis are added water, big fire decocts to boiling, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 40 minutes slowly, must stirring repeatedly in the process decocted, and filter, filtrate is for subsequent use;
(6) collagen protein, ossein, Colla Corii Asini and calcium gluconate tablet are dropped in step (5) gained filtrate, intense fire is fried open rear continuous stirring 6 minutes, turns slow fire boiling, and when filtrate is concentrated into 1/2 of original volume, cease fire, filter, filtrate is for subsequent use;
(7) step (1)-(4) gained smalls and step (6) gained filtrate are mixed, heating, when being heated to 35 DEG C, adds Mel, after Mel melts completely, repeatedly rubs, and evenly, be twisted into medicated strip, cutting in bulk, is kneaded into sugar pill, bottles and get final product.。
test example 1the clinical practice of the sugar pill of embodiment 5 gained acute glomerulonephritis of baby: we have randomly drawed 400 patients and have tested (400 patients have acute glomerulonephritis of baby in various degree), be divided into experimental group and matched group, wherein girl 200 example, boy 200 example.Before test 1 week, carry out Continuous Observation to this crowd, record symptom and change, be divided into two groups, experimental group and matched group at random, and experimental group uses embodiment 5 products obtained therefrom, and matched group only uses the medicine of acute glomerulonephritis of baby.
Using method: for making this medicine reach optimum therapeuticing effect, gets sugar pill 2-4 grain of the present invention at every turn, and the morning, noon and afternoon respectively once, 10 days are a course for the treatment of.Curative effect situation criterion: 1, cure: use after this product, malaise symptoms all disappears, 2, effectively, after using this product, malaise symptoms alleviates or partial disappearance; 3, invalid, after using this product, malaise symptoms is unchanged.We have carried out accurate statistics and mathematical analysis to experimental data.Specific experiment result is as following table:
Table 1: two groups of Clinical efficacy comparison [example] tables 1
Table 1
Interpretation of result: experimental group and matched group all can reach acute glomerulonephritis of baby effect within the observation period, but the obvious effective rate of experimental group and total effective rate are apparently higher than matched group, and in matched group, have also appeared the case of untoward reaction, so the embodiment of the present invention 5 gained sugar pill has significant curative effect in acute glomerulonephritis of baby, and all select pure natural Raw through the suitable process of preparing Chinese medicine due to this product, easy to use, and it is without any side effects, also can not cause burden to nervous system, can not dependence and addiction be caused.

Claims (10)

1. treat a sugar pill for acute glomerulonephritis of baby, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Ginseng 5-15 part, Radix Glycyrrhizae 3-8 part, Pericarpium Citri Reticulatae 5-10 part, Massa Medicata Fermentata 2-4 part, collagen protein 4-11 part, ossein 8-16 part, pear 7-15 part, Flos Lonicerae 5-15 part, Semen Coicis 3-7 part, saponin rice 6-10 part, Bulbus Fritillariae Cirrhosae 3-9 part, Colla Corii Asini 6-9 part, shrimp 0.5-1.5 part, Arillus Longan 4-8 part, calcium gluconate tablet 3-8 part, Fructus Litchi 5-10 part.
2. the sugar pill for the treatment of acute glomerulonephritis of baby according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Ginseng 8-13 part, Radix Glycyrrhizae 4-7 part, Pericarpium Citri Reticulatae 6-9 part, Massa Medicata Fermentata 2.5-3.5 part, collagen protein 6-9 part, ossein 10-14 part, pear 9-13 part, Flos Lonicerae 8-13 part, Semen Coicis 4-6 part, saponin rice 7-9 part, Bulbus Fritillariae Cirrhosae 5-7 part, Colla Corii Asini 7-8 part, shrimp 0.8-1.3 part, Arillus Longan 5-7 part, calcium gluconate tablet 4-7 part, Fructus Litchi 6-9 part.
3. the sugar pill for the treatment of acute glomerulonephritis of baby according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Ginseng 10 parts, 5 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 7 parts, Massa Medicata Fermentata 3 parts, collagen protein 8 parts, ossein 12 parts, pear 11 parts, Flos Lonicerae 10 parts, Semen Coicis 5 parts, saponin rice 8 parts, Bulbus Fritillariae Cirrhosae 6 parts, 7.5 parts, Colla Corii Asini, shrimp 1 part, Arillus Longan 6 parts, calcium gluconate tablet 5.5 parts, Fructus Litchi 7.5 parts.
4. the preparation method of the sugar pill of the treatment acute glomerulonephritis of baby according to any one of claim 1-3, is characterized in that: step is as follows:
(1) fresh Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri Reticulatae and Massa Medicata Fermentata are picked clean impurity, clean and run through, be cut into filament and put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 3-7 day, Cheng Gan, it is stand-by to grind to form smalls;
(2) shrimp is cleaned removal palpus, be layered on uniformly in container, even with cooking wine spray, the stewing 2-4 hour of sealing, dryouied by pot, put into edible oil, the consumption of edible oil is 2-4 times of shrimp consumption, the shrimp of having boiled in a covered pot over a slow fire is dropped into after oily heat, fried 5-15 minute, take out, dry in the air 3-8 minute, grind to form fine powder, cross 80-120 mesh sieve stand-by;
(3) fresh Arillus Longan and Fructus Litchi to be shelled enucleation, be placed in baking box by Arillus Longan and Fructus Litchi, roasting 4-9 minute, it is stand-by to grind to form smalls;
(4) by pear clean, peeling, stripping and slicing, be placed on steaming tray, steam 5-15 minute, be pounded thick paste thing with battle of making dough, be placed in fried dry in hot pot stand-by;
(5) saponin rice and Semen Coicis are added water, big fire decocts to boiling, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 30-50 minute slowly, must stirring repeatedly in the process decocted, and filter, filtrate is for subsequent use;
(6) collagen protein, ossein, Colla Corii Asini and calcium gluconate tablet are dropped in step (5) gained filtrate, intense fire is fried open rear continuous stirring 3-8 minute, turns slow fire boiling, and when filtrate is concentrated into 1/2 of original volume, cease fire, filter, filtrate is for subsequent use;
(7) step (1)-(4) gained smalls and step (6) gained filtrate are mixed, heating, when being heated to 30-40 DEG C, adds Mel, after Mel melts completely, repeatedly rubs, and evenly, be twisted into medicated strip, cutting in bulk, is kneaded into sugar pill, bottles and get final product.
5. preparation method according to claim 4, it is characterized in that: step (1) is cut into filament puts in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, it is (preferred that taking-up is dried in the air 4-6 day, be cut into filament to put in food steamer and spray rice wine big fire and boil rapidly, until all steaming thoroughly, taking out and drying in the air 5).
6. preparation method according to claim 4, is characterized in that: step (2) shrimp is cleaned and removes palpus, is layered on uniformly in container, even with cooking wine spray, within stewing 2.5-3.5 hour, (preferred, the clean removal of shrimp must in sealing, be layered on uniformly in container, even with cooking wine spray, stewing 3 hours of sealing).
7. preparation method according to claim 4, it is characterized in that: the consumption of step (2) edible oil is 2.5-3.5 times of shrimp consumption, the shrimp of having boiled in a covered pot over a slow fire is dropped into after oily heat, fried 8-13 minute (preferred, the consumption of edible oil is 3 times of shrimp consumption, the shrimp of having boiled in a covered pot over a slow fire is dropped into, fried 10 minutes) after oily heat.
8. preparation method according to claim 4, is characterized in that: Arillus Longan and Fructus Litchi are placed in baking box by step (3), roasting 5-8 minute (preferred, Arillus Longan and Fructus Litchi are placed in baking box, roasting 7 minutes).
9. preparation method according to claim 4, it is characterized in that: step (5) drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmer slowly 35-45 minute (preferred, drop into clean drain away the water Flos Lonicerae, Bulbus Fritillariae Cirrhosae, little fire simmers 40 minutes slowly).
10. preparation method according to claim 4, is characterized in that: step (6) intense fire is fried open rear continuous stirring 5-7 minute (preferred, intense fire is fried open rear continuous stirring 6 minutes).
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