CN104740011A - Essential oil for calming nerves and promoting sleep and preparation method thereof - Google Patents

Essential oil for calming nerves and promoting sleep and preparation method thereof Download PDF

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Publication number
CN104740011A
CN104740011A CN201510159565.9A CN201510159565A CN104740011A CN 104740011 A CN104740011 A CN 104740011A CN 201510159565 A CN201510159565 A CN 201510159565A CN 104740011 A CN104740011 A CN 104740011A
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quintessence oil
calming
fructus citri
oil
citri limoniae
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马瑞君
刘晓生
吴清韩
朱慧
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Hanshan Normal University
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Hanshan Normal University
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Abstract

The invention discloses an essential oil for calming nerves and promoting sleep and a preparation method thereof. The essential oil is prepared from the following raw materials in parts by weight: 30-80 parts of lemon essential oil, 0-50 parts of lavender essential oil, 0-30 parts of flores anthemidis essential oil, and 0-30 parts of benzoin essential oil. The preparation method comprises the following steps: uniformly mixing the lemon essential oil, the lavender essential oil, the flores anthemidis essential oil, and the benzoin essential oil. The essential oil of the embodiment provided by the invention is suitable for different people, has a wide application scope, has the functions of calming the nerves and reducing the pressure, easing the emotional tension, promoting the sleep and calming the mind and has the effect of prolonging the sleeping time.

Description

A kind of for short quintessence oil of sleeping and preparation method thereof of calming the nerves
Technical field
The present invention relates to essential oil and make field, in particular to a kind of for short quintessence oil of sleeping and preparation method thereof of calming the nerves.
Background technology
Nowadays, along with allegro life, the life stress of people is also generally larger, insomnia or sleep quality is not good brings greatly painful and psychological burden, have difficulty in going to sleep, do not sleep heavy or the length of one's sleep short be its cardinal symptom.Patient all has from the scholar of youth, elderly population and successful personage, and students even have and to cause because chronic insomnia is agonizing committing suiside.In currently available technology, mainly take to take as stable Western medicine or the reinforcing the heart class Chinese medicine of calming the nerves of waiting carries out effective relief of symptoms, also have and carry out auxiliary treatment by methods such as quintessence oil champignon, fragrant pillow.
But long-term taking Western medicine always allows the popular feeling have doubt, worry whether side effect causes more greatly other diseases; Chinese medicine relatively easily accepts, but decocting herb trouble, particularly concerning students, more difficult realization, and take effect slowly.Quintessence oil champignon needs power supply, the power-off but school can regularly turn off the light usually, and effect is still needed and will be confirmed not say, it also can bring certain potential safety hazard owing to needing electricity consumption; In addition, fragrant pillow effect is used to be difficult to lasting and cost compare is high.
In view of this, special proposition the present invention.
Summary of the invention
The first object of the present invention is to provide a kind of short quintessence oil of sleeping of calming the nerves, described quintessence oil overcomes above-mentioned technical problem, this quintessence oil is applicable to different crowd, applied widely, there is decompression of calming the nerves, keeping tensions down emotion, hypnotic and curative effect with all worries set aside, also have and extend the advantage such as length of one's sleep.
The second object of the present invention is to provide a kind of preparation method of described short quintessence oil of sleeping of calming the nerves, and the method has and makes simple, easy to operate and cost of manufacture is low, the advantage such as active ingredient of each component in can completely retention of oil.
In order to realize above-mentioned purpose of the present invention, spy by the following technical solutions:
The short quintessence oil of sleeping of calming the nerves of the embodiment of the present invention, makes primarily of following raw material: in volume parts, Fructus Citri Limoniae quintessence oil 30-80 part, Herba Lysimachiae foenum-graeci quintessence oil 0-50 part, Roman Herba Cancriniae Discoideae quintessence oil 0-30 part, Benzoinum quintessence oil 0-30 part.
The short quintessence oil of sleeping of calming the nerves of the embodiment of the present invention, can directly be made up of a kind of composition of Fructus Citri Limoniae quintessence oil, Fructus Citri Limoniae quintessence oil mainly extracts its essence substance gained by any one method in steam distillation, milling process, extraction, carbon dioxide critical extraction from Fructus Citri Limoniae peel.Fructus Citri Limoniae quintessence oil has the pure and fresh fragrance of Fructus Citri Limoniae, can spirit of refreshing oneself be helped, alleviate irritated, also have much positive opsonic action for skin and health, wherein be rich in abundant vitamin C, be particularly useful for the oily skin symptoms such as whitening, convergence, Bergamot Mint Extract, treatment comedo.There is happy nice and cool and fresh sense, pure and fresh impression can be brought to people, thus reach the emotion of releive anxiety or anxiety.The Fructus Citri Limoniae quintessence oil that the present invention selects preferably is made up of following several Main Ingredients and Appearance: with volume percentage, limonene 50-60%, γ-terpinene 10-20%, nopinene 10-20%.The percent by volume of this composition of limonene on the market in general Fructus Citri Limoniae quintessence oil does not reach 50%, if but this component content in Fructus Citri Limoniae quintessence oil is too low, the quintessence oil finished product so prepared does not reach yet of the present inventionly has short dormancy of calming the nerves, extend the effect of the length of one's sleep, if certain contrary constituent content is too high, reverse effect can be played again, use rear whole people to become to have dizzy spells, there is no spirit, therefore when specifically selecting this raw material of Fructus Citri Limoniae quintessence oil, need to detect Main Ingredients and Appearance contained by it whether in suitable scope, thus make curative effect best, it also can be able to take the mode of foregoing description to prepare voluntarily by commercially available acquisition, but no matter take the content of which kind of its active ingredient of mode preferably in suitable scope.
In addition, be in the consideration of Financial cost and the consideration of people's oneself's impression in use, people can also be made when using quintessence oil in order to reduce costs, its soft aroma and delicate fragrance, can accept by many people, it preferably also comprises other three kinds of raw materials, Herba Lysimachiae foenum-graeci quintessence oil, Roman Herba Cancriniae Discoideae quintessence oil, Benzoinum quintessence oil, and Fructus Citri Limoniae quintessence oil is also larger as its dosage of a kind of raw material evident in efficacy, volume parts is 30-80 part, be preferably 50-80 part, more excellent is 60-70 part, can also choose 35 parts, 40 parts and 45 parts etc.
The general addition of Herba Lysimachiae foenum-graeci quintessence oil is 0-50 part, is preferably 10-30 part, and more excellent is 15-35 part, can also select 20 parts, 25 parts and 38 parts etc.; The abnormal smells from the patient of Herba Lysimachiae foenum-graeci quintessence oil very pure and fresh simple and elegant own, can match with Fructus Citri Limoniae quintessence oil and mix softer quintessence oil abnormal smells from the patient, have nervous gently, decompression is calm, equilibrium nerve and changeable in mood effect, especially to nervus centralis, there is good sedation, therefore preferably take suitable volume parts and prepare quintessence oil as raw material.Same, described Herba Lysimachiae foenum-graeci quintessence oil is preferably containing following several Main Ingredients and Appearance: with volume percentage, linalool 35-45%, acetic acid linalool 20-30%, acetic acid lavandula angustifolia ester 10-25%, alpha-terpineol 4-15%.Preferably detecting contained Main Ingredients and Appearance when selecting, only having often kind of composition in suitable indication range, its effect of quintessence oil prepared as raw material is just best.Herba Lysimachiae foenum-graeci quintessence oil, by commercially available acquisition, also can adopt following extracting method: from lavandula angustifolia herb, adopt the material that skims the cream off milk of any one method in steam distillation, milling process, extraction, carbon dioxide critical extraction to obtain.
The general addition of Roman Herba Cancriniae Discoideae quintessence oil is 0-30 part, is preferably 5-10 part, and more excellent is 8-10 part, can also select 15 parts, 20 parts and 25 parts etc.; Roman Herba Cancriniae Discoideae quintessence oil itself has that balance is calm, emotion is pacified, alleviate skin aches and the effect of swollen joint, strengthening digestive system and the intestines and stomach coordinating, especially the effect of pacifying is not equipped with to insomnia, anxiety and melancholy, anxiety can be alleviated, calm mood, therefore its better effects if of the quintessence oil making to prepare that cooperatively interacts as raw material and other raw materials; The Main Ingredients and Appearance of Roman Herba Cancriniae Discoideae quintessence oil is isopropyl naphthalene, the content of this composition preferably accounts for more than 20%, so that the requirement of the curative effect that will reach can be met, Roman Herba Cancriniae Discoideae quintessence oil, by commercially available acquisition, also can adopt following extracting method: the extracting method of described Roman Herba Cancriniae Discoideae quintessence oil is from Flos Chrysanthemi, adopt any one method in steam distillation, milling process, extraction, carbon dioxide critical extraction to skim the cream off milk material gained.
The general addition of Benzoinum quintessence oil is 0-30 part, it is preferably 5-10 part, more excellent is 8-10 part, 6 parts, 7 parts and 9 parts etc. can also be selected, Benzoinum quintessence oil itself has fragrant and sweet abnormal smells from the patient, good smell can well be in harmonious proportion the abnormal smells from the patient of quintessence oil, and have calm the nerves, effect of keeping tensions down emotion, Main Ingredients and Appearance and consumption is preferably selected to be following several Benzoinum quintessence oil when selecting: with volume percentage, 3-phenyl-2-acrylic aldehyde 40-50%, benzyl cinnamate 40-50%, Benzyl Benzoate fat 8-15%; Often kind of composition and consumption are preferably in suitable scope, select the Benzoinum quintessence oil with this specific composition as raw material, the quality of finished prepared can be made higher, and evident in efficacy, and people also can play short effect of sleeping of calming the nerves in use very soon.Therefore inventor is all by having done a large amount of experiments after detecting its each index when specifically selecting often kind of raw material, just obtains optimum composition and optimum consumption.Benzoinum quintessence oil also can be obtained by following extracting method by commercially available acquisition: from fragrant flower of resting in peace, adopt any one method in steam distillation, milling process, extraction, carbon dioxide critical extraction to skim the cream off milk material gained.
The embodiment of the present invention additionally provides a kind of preparation method of short quintessence oil of sleeping of calming the nerves, and comprises the steps:, by described Fructus Citri Limoniae quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Roman Herba Cancriniae Discoideae quintessence oil and described Benzoinum quintessence oil mix homogeneously, to obtain final product.This preparation method operation is upper fairly simple, but curative effect is but very remarkable, it uses with the state of oily liquids after can mixing, also the mode continuing again to process can be selected, be prepared into gel solids dosage form, when specifically using, put one piece of diameter and be about the slow release colloidal solid ball of 1cm in the left and right sides of medicated pillow, using method is very simple.
The concrete grammar being prepared into gel solids dosage form is as follows:
First get 500ml distilled water and be heated to 80-90 DEG C, add sodium stearate 9-11g, sodium alginate 6-8g, agar 5-6g, tween 0.01ml, use constant temperature blender with magnetic force, rotating speed is 200-250r/min, 2-3h is stirred under the constant temperature of 80-90 DEG C, obtained coagulant liquid, preserves stand-by in 50-60 DEG C of water bath with thermostatic control.Then the compound essential Oil mixed and coagulant liquid are added in high pressure homogenize equipment, at temperature 75-85 DEG C, homogenizing four times under the condition of pressure 30MPa, each 7min, mould poured into by mixed liquor after homogenizing, to be cooled solidifying can be packed, and obtains finished product, is named gel type air freshener.
Champignon therapy principle is applied in the preparation of gel type air freshener by the present invention, and various combination is devised to 4 kinds of fragrant Chinese herbal medicine quintessence oils, can hear fragrant hobby according to the person's of taking good care of health and each one and carry out compatibility, being applied to calms the nerves takes good care of, and improves IAQ (indoor air quality).In addition, the processing technology of freshener of originally calming the nerves product is comparatively simple, Product Safety is high, volatility is low, practical, and being applicable to the place such as household, company, is the product of a environmental protection.
Compared with prior art, beneficial effect of the present invention is:
(1) good drug efficacy, evident in efficacy, Fructus Citri Limoniae quintessence oil has happiness, feeling nice and cool has clever clearly fresh sense, makes people's mental relaxation; Herba Lysimachiae foenum-graeci quintessence oil has sedation to central nervous system; Roman Herba Cancriniae Discoideae quintessence oil fragrance wet dissipation, is not equipped with the effect of pacifying to insomnia, anxiety and melancholy, can alleviates anxiety, calm mood thread; Benzoinum quintessence oil can removing dampness by means of aromatics, keeping tensions down emotion be calmed the nerves;
(2) quintessence oil of the embodiment of the present invention plays decompression of calming the nerves, keeping tensions down emotion, hypnotic and with all worries set aside, and there is obvious effect prolongation length of one's sleep;
(3) property of medicine is good, and medication is convenient, and dosage form is changeable, can meet the demand of different crowd, and patient is easy to accept, and does not need electricity consumption, exists, especially facilitate students to use without potential safety hazard; Cost of material is low, the cost of one week consumption only about 10 yuan.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but it will be understood to those of skill in the art that the following example only for illustration of the present invention, and should not be considered as limiting the scope of the invention.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, be and can buy by commercially available the conventional products obtained.
Embodiment 1
The concrete preparation method of short quintessence oil of sleeping of calming the nerves is as follows:
1) first following raw material is obtained respectively by the mode of preparation or purchase: Fructus Citri Limoniae quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Roman Herba Cancriniae Discoideae quintessence oil and Benzoinum quintessence oil, Fructus Citri Limoniae quintessence oil adopts extraction by steam distillation out from Fructus Citri Limoniae peel, its Main Ingredients and Appearance is after testing: by volume percentage ratio, limonene 50%, γ-terpinene 10%, nopinene 10%, other compositions account for 30%.Other three kinds of quintessence oils obtain by buying, and the Main Ingredients and Appearance of Herba Lysimachiae foenum-graeci quintessence oil is: linalool 35%, acetic acid linalool 30%, acetic acid lavandula angustifolia ester 25%, alpha-terpineol 4%, and other compositions account for 6%; The Main Ingredients and Appearance of Roman Herba Cancriniae Discoideae quintessence oil is that isopropyl naphthalene occupies 20%; The Main Ingredients and Appearance of Benzoinum quintessence oil is as follows: 3-phenyl-2-acrylic aldehyde 40%, benzyl cinnamate 50%, Benzyl Benzoate fat 8%, other compositions 2%;
2) four kinds of folk prescription quintessence oils are carried out mixing preparation according to following ratio: in volume parts, 70 parts of Fructus Citri Limoniae quintessence oil, 15 parts of Herba Lysimachiae foenum-graeci quintessence oil, 10 parts of Roman Herba Cancriniae Discoideae quintessence oils, 5 parts of Benzoinum quintessence oils, obtain mixed essential oil after being uniformly mixed;
3) subpackage, labeling and after adding outer package, get product.
Embodiment 2
The concrete preparation method of short quintessence oil of sleeping of calming the nerves is as follows:
1) first following raw material is obtained respectively by the mode of preparation or purchase: Fructus Citri Limoniae quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Roman Herba Cancriniae Discoideae quintessence oil and Benzoinum quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil is the essence substance gained adopting chemical solvent extraction to extract from lavandula angustifolia herb, its Main Ingredients and Appearance is after testing: by volume percentage ratio, linalool 45%, acetic acid linalool 20%, acetic acid lavandula angustifolia ester 10%, alpha-terpineol 15%, other compositions account for 10%; Other three kinds of quintessence oils obtain by buying, and the composition of Fructus Citri Limoniae quintessence oil is: limonene 60%, γ-terpinene 20%, nopinene 20%; The Main Ingredients and Appearance of Roman Herba Cancriniae Discoideae quintessence oil is that isopropyl naphthalene occupies 30%; The Main Ingredients and Appearance of Benzoinum quintessence oil is as follows: 3-phenyl-2-acrylic aldehyde 50%, benzyl cinnamate 40%, Benzyl Benzoate fat 10%;
2) four kinds of folk prescription quintessence oils are carried out mixing preparation according to following ratio: in volume parts, 80 parts of Fructus Citri Limoniae quintessence oil, 10 parts of Herba Lysimachiae foenum-graeci quintessence oil, 5 parts of Roman Herba Cancriniae Discoideae quintessence oils, 5 parts of Benzoinum quintessence oils, obtain mixed essential oil after being uniformly mixed;
3) subpackage, labeling and after adding outer package, get product.
Embodiment 3
The concrete preparation method of short quintessence oil of sleeping of calming the nerves is as follows:
1) first following raw material is obtained respectively by the mode of preparation or purchase: Fructus Citri Limoniae quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Roman Herba Cancriniae Discoideae quintessence oil and Benzoinum quintessence oil, Roman Herba Cancriniae Discoideae quintessence oil is from Flos Chrysanthemi, adopt carbon dioxide critical extraction to extract, and its Main Ingredients and Appearance is that isopropyl naphthalene occupies 20% after testing; Other three kinds of quintessence oils obtain by buying, and Fructus Citri Limoniae quintessence oil is percentage ratio by volume, and limonene 50%, γ-terpinene 10%, nopinene 10%, other compositions account for 30%.The Main Ingredients and Appearance of Herba Lysimachiae foenum-graeci quintessence oil is: linalool 35%, acetic acid linalool 30%, acetic acid lavandula angustifolia ester 25%, alpha-terpineol 4%, and other compositions account for 6%; The Main Ingredients and Appearance of Benzoinum quintessence oil is as follows: 3-phenyl-2-acrylic aldehyde 40%, benzyl cinnamate 40%, Benzyl Benzoate fat 15%, other compositions 5%;
2) four kinds of folk prescription quintessence oils are carried out mixing preparation according to following ratio: in volume parts, 50 parts of Fructus Citri Limoniae quintessence oil, 35 parts of Herba Lysimachiae foenum-graeci quintessence oil, 10 parts of Roman Herba Cancriniae Discoideae quintessence oils, 5 parts of Benzoinum quintessence oils; Mixed essential oil is obtained after being uniformly mixed;
3) subpackage, labeling and after adding outer package, get product.
Embodiment 4
1) Fructus Citri Limoniae quintessence oil is obtained by commercially available purchase, for subsequent use;
2) get 500ml distilled water and be heated to 80-90 DEG C, add sodium stearate 9-11g, sodium alginate 6-8g, agar 5-6g, tween 0.01ml, use constant temperature blender with magnetic force, rotating speed is 200-250r/min, 2-3h is stirred under the constant temperature of 80-90 DEG C, obtained coagulant liquid, preserves stand-by in 50-60 DEG C of water bath with thermostatic control;
3) Fructus Citri Limoniae quintessence oil and coagulant liquid are mixed according to the volume ratio of 1:1 add in high pressure homogenize equipment, at temperature 75-85 DEG C, homogenizing four times under the condition of pressure 30MPa, each 7min, mould poured into by the mixed liquor after homogenizing, to be cooled solidifying can be packed, and obtains finished product.
Embodiment 5
1) obtain Fructus Citri Limoniae quintessence oil and Herba Lysimachiae foenum-graeci quintessence oil by commercially available purchase, detecting its effective ingredient of Fructus Citri Limoniae quintessence oil is: limonene 55%, γ-terpinene 15%, nopinene 20%, and other compositions account for 10%; It is as follows that Herba Lysimachiae foenum-graeci quintessence oil detects its effective ingredient: linalool 35%, acetic acid linalool 30%, acetic acid lavandula angustifolia ester 25%, alpha-terpineol 4%, and other compositions account for 6%;
2) two kinds of folk prescription quintessence oils are carried out mixing preparation according to following ratio: in volume parts, 30 parts of Fructus Citri Limoniae quintessence oil, 50 parts of Herba Lysimachiae foenum-graeci quintessence oil obtain mixed essential oil after being uniformly mixed;
3) subpackage, labeling and after adding outer package, get product.
Embodiment 6
1) preparation method of this step is identical with embodiment 1;
2) four kinds of folk prescription quintessence oils are carried out mixing preparation according to following ratio: in volume parts, 60 parts of Fructus Citri Limoniae quintessence oil, 30 parts of Herba Lysimachiae foenum-graeci quintessence oil, 30 parts of Roman Herba Cancriniae Discoideae quintessence oils, 10 parts of Benzoinum quintessence oils, obtain mixed essential oil after being uniformly mixed;
3) subpackage, labeling and after adding outer package, get product.
Embodiment 7
1) preparation method of this step is identical with embodiment 2;
2) four kinds of folk prescription quintessence oils are carried out mixing preparation according to following ratio: in volume parts, 60 parts of Fructus Citri Limoniae quintessence oil, 30 parts of Herba Lysimachiae foenum-graeci quintessence oil, 8 parts of Roman Herba Cancriniae Discoideae quintessence oils, 30 parts of Benzoinum quintessence oils, obtain mixed essential oil after being uniformly mixed;
3) subpackage, labeling and after adding outer package, get product.
Embodiment 8
1) preparation method of this step is identical with embodiment 3;
2) four kinds of folk prescription quintessence oils are carried out mixing preparation according to following ratio: in volume parts, 30 parts of Fructus Citri Limoniae quintessence oil, 30 parts of Herba Lysimachiae foenum-graeci quintessence oil, 8 parts of Roman Herba Cancriniae Discoideae quintessence oils, 8 parts of Benzoinum quintessence oils, obtain mixed essential oil after being uniformly mixed;
3) subpackage, labeling and after adding outer package, get product.
Experimental example 1
Method of testing ND-97 digitized electroencephalograph test (high-tech company, Shanghai)
Principle: brain wave derives from the dendron electrical activity of cortex pyramidal cell, generally believe be many neuronal cell extrinsic currents produce the summation of electric field, become one of important indicator of evaluation central nervous system change.Current people under study for action, according to the frequency finding each species rhythm in brain wave, brain wave is divided into following 4 types: the β ripple that the α ripple that the θ ripple that the δ ripple that frequency is 0.5-3.5Hz, frequency are 4-7.5Hz, frequency are 8-13.5Hz, frequency are 14-30Hz.Though do not verify the mechanism of Chu's brain wave completely, but there are some researches show that the Nervous and Mental Factors of people has a great impact brain electrical acti, and when the mental status of people changes, we can go the information in electrical activity source in inverting brain with the current potential observed from scalp.Wherein, when psychentonia or excited time, beta response is obviously strengthened, and β ripple can as an index of being emotionally stable to reflect the emotion changes of people; When mood is loosened and realized concentrated, electroencephalogram is based on alpha rhythm, and alpha rhythm is the basilic rhythm of normal adult human electroencephalogramafter after running; When human brain be in hypoarouse or daydream, psycheism, in the subconscious activity such as to doze off, θ ripple can significantly strengthen; When adult is in sleep period, its ratio regular meeting significantly improves.Therefore, the mental status and some mental activity of indirectly appraiser can be come by brain wave analysis, the short dormancy effect of calming the nerves evaluating plants essential oil by analyzing θ ripple proportion in brain wave is mainly want in this kind of research, and this evaluation methodology has been commonly used to medicine and has calmed the nerves the evaluation of effect.
60 volunteers recruited in university students, according to the electrode tip that the standard method of instrumentation is laid at volunteer's head, student is allowed to inhale the compound essential Oil of bromine single quintessence oil and different ratio concentration respectively, instrument records the change of electroencephalogram automatically, by analyzing θ ripple proportion in brain wave, the most preferred embodiment formula having filtered out the quintessence oil with short dormancy effect of obviously calming the nerves has 3 kinds:
Embodiment 1:70 part Fructus Citri Limoniae quintessence oil, 15 parts of Herba Lysimachiae foenum-graeci quintessence oil, 10 parts of Roman Herba Cancriniae Discoideae quintessence oils, 5 parts of Benzoinum quintessence oils;
Embodiment 2:80 part Fructus Citri Limoniae quintessence oil, 10 parts of Herba Lysimachiae foenum-graeci quintessence oil, 5 parts of Roman Herba Cancriniae Discoideae quintessence oils, 5 parts of Benzoinum quintessence oils;
Embodiment 3:50 part Fructus Citri Limoniae quintessence oil, 35 parts of Herba Lysimachiae foenum-graeci quintessence oil, 10 parts of Roman Herba Cancriniae Discoideae quintessence oils, 5 parts of Benzoinum quintessence oils;
Experimental example 2
Not good or be difficult to the university students 20 that falls asleep to readme sleep quality, first every student length of one's sleep at ordinary times of nearly 3 days is added up, drip at bedside the quintessence oil executing embodiment of the present invention 1-2 before allowing them sleep again, the university students of 1-10 position adopts the quintessence oil of the embodiment of the present invention 1, the university students of 11-20 position adopts the quintessence oil of the embodiment of the present invention 2, repeat 3 days, add up the length of one's sleep of every day, average as test after data, then by the method that the paired sample T-in SPSS statistical software checks, carry out the relative analysis before and after with oil, see that it has there was no significant difference.
Table 1 uses the statistics (unit: hour) of the length of one's sleep before and after quintessence oil of the present invention
1 2 3 4 5 6 7 8 9 10
Before oil 4.0 5.0 3. 5.0 4.0 4.5 2.0 4.0 5.0 5.5
After oil 6.0 5.0 6.5 6.0 6.5 5.0 4.0 4.0 5.5 7.0
Numbering 11 12 13 14 15 16 17 18 19 20
Before oil 4.0 4.0 5.5 3.0 3.5 3.5 4.0 4.5 5.0 5.0
After oil 4.0 6.0 8.0 6.0 4.0 4.0 4.0 7.5 6.0 5.0
As can be seen from Table 1, after using the quintessence oil of the embodiment of the present invention, have the effect of the significant prolongation length of one's sleep, therefore the quintessence oil good drug efficacy prepared of the present invention, evident in efficacy; The quintessence oil of the embodiment of the present invention plays decompression of calming the nerves, keeping tensions down emotion, hypnotic and with all worries set aside, and there is obvious effect prolongation length of one's sleep.
The method adopting the paired sample T-in SPSS statistical software to check below, carry out the relative analysis before and after with oil, see that it has there was no significant difference:
Table 2 matches the inspection of T-assay-paired sample
Two-tailed test probability P=0.000<0.001, therefore can think the pole significant prolongation length of one's sleep inhaled after bromine composite essential oil
As can be seen from Table 2, after verified, the pole significant prolongation length of one's sleep inhaled after bromine composite essential oil can be thought, and the quintessence oil of the embodiment of the present invention is applicable to difficulty falling asleep, dreaminess, Yi Xing, uses in the environment that daytime, listless person lived.
Although illustrate and describe the present invention with specific embodiment, however it will be appreciated that can to make when not deviating from the spirit and scope of the present invention many other change and amendment.Therefore, this means to comprise all such changes and modifications belonged in the scope of the invention in the following claims.

Claims (10)

1. calm the nerves and urge a quintessence oil for dormancy, it is characterized in that, make primarily of following raw material: in volume parts, Fructus Citri Limoniae quintessence oil 30-80 part, Herba Lysimachiae foenum-graeci quintessence oil 0-50 part, Roman Herba Cancriniae Discoideae quintessence oil 0-30 part, Benzoinum quintessence oil 0-30 part.
2. a kind of short quintessence oil of sleeping of calming the nerves according to claim 1, is characterized in that, make: in volume parts primarily of following raw material, Fructus Citri Limoniae quintessence oil 50-80 part, Herba Lysimachiae foenum-graeci quintessence oil 10-30 part, Roman Herba Cancriniae Discoideae quintessence oil 5-10 part, Benzoinum quintessence oil 5-10 part.
3. a kind of short quintessence oil of sleeping of calming the nerves according to claim 1, is characterized in that, make: in volume parts primarily of following raw material, Fructus Citri Limoniae quintessence oil 60-70 part, Herba Lysimachiae foenum-graeci quintessence oil 15-35 part, Roman Herba Cancriniae Discoideae quintessence oil 8-10 part, Benzoinum quintessence oil 8-10 part.
4. a kind of short quintessence oil of sleeping of calming the nerves according to claim 1, it is characterized in that, the Main Ingredients and Appearance of described Fructus Citri Limoniae quintessence oil is as follows: with volume percentage, limonene 50-60%, γ-terpinene 10-20%, nopinene 10-20%.
5. a kind of short quintessence oil of sleeping of calming the nerves according to claim 1, it is characterized in that, the Main Ingredients and Appearance of described Herba Lysimachiae foenum-graeci quintessence oil is as follows: with volume percentage, linalool 35-45%, acetic acid linalool 20-30%, acetic acid lavandula angustifolia ester 10-25%, alpha-terpineol 4-15%.
6. a kind of short quintessence oil of sleeping of calming the nerves according to claim 1, it is characterized in that, the Main Ingredients and Appearance of described Roman Herba Cancriniae Discoideae quintessence oil is isopropyl naphthalene.
7. a kind of short quintessence oil of sleeping of calming the nerves according to claim 1, it is characterized in that, the Main Ingredients and Appearance of described Benzoinum quintessence oil is as follows: with volume percentage, 3-phenyl-2-acrylic aldehyde 40-50%, benzyl cinnamate 40-50%, Benzyl Benzoate fat 8-15%.
8. the short quintessence oil of sleeping of calming the nerves according to any one of claim 1-7, it is characterized in that, the extracting method of described Fructus Citri Limoniae quintessence oil is from Fructus Citri Limoniae peel, adopt any one method in steam distillation, milling process, extraction, carbon dioxide critical extraction to skim the cream off milk material gained;
The extracting method of preferred described Herba Lysimachiae foenum-graeci quintessence oil is from lavandula angustifolia herb, adopt any one method in steam distillation, milling process, extraction, carbon dioxide critical extraction to skim the cream off milk material gained;
The extracting method of preferred described Roman Herba Cancriniae Discoideae quintessence oil is from Flos Chrysanthemi, adopt any one method in steam distillation, milling process, extraction, carbon dioxide critical extraction to skim the cream off milk material gained;
The extracting method of preferred described Benzoinum quintessence oil is from fragrant flower of resting in peace, adopt any one method in steam distillation, milling process, extraction, carbon dioxide critical extraction to skim the cream off milk material gained.
9. the preparation method of the short quintessence oil of sleeping of calming the nerves described in any one of claim 1-8, is characterized in that, comprise the steps:, by described Fructus Citri Limoniae quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Roman Herba Cancriniae Discoideae quintessence oil and described Benzoinum quintessence oil mix homogeneously, to obtain final product.
10. the preparation method of short quintessence oil of sleeping of calming the nerves according to claim 9, it is characterized in that, after described Fructus Citri Limoniae quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Roman Herba Cancriniae Discoideae quintessence oil and described Benzoinum quintessence oil mixing and stirring, also comprise the step being prepared into solid gel shape.
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CN105213541A (en) * 2015-09-29 2016-01-06 宗欣生态科技(上海)有限公司 Rose compound essential oil improving insomnia due to pressure and preparation method thereof
CN106880709A (en) * 2017-03-30 2017-06-23 厦门正合意生物科技有限公司 A kind of relieving insomnia for improving brain wave helps the composite essential oil of sleep
CN107144685A (en) * 2017-05-27 2017-09-08 无限极(中国)有限公司 A kind of screening technique with refreshing effect essential oil or its product
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CN110292573A (en) * 2019-06-12 2019-10-01 颇黎芳香医药科技(上海)有限公司 A kind of relieve stagnation sleeping compound essential oil
CN111317753A (en) * 2020-03-11 2020-06-23 北京茂思商贸有限公司 Plant essential oil composition with effects of calming and helping sleep and preparation method thereof
CN111973672A (en) * 2020-09-11 2020-11-24 杜浩 Sleep-aiding composition and preparation method thereof
CN112121095A (en) * 2020-08-19 2020-12-25 歌曼丽(苏州)大健康产业发展有限公司 Hypnotic essential oil composition with quick response and preparation method thereof
CN113604280A (en) * 2021-07-19 2021-11-05 上海应用技术大学 Lavender compound essential oil, preparation method and evaluation method thereof
CN114129630A (en) * 2021-11-22 2022-03-04 河北泰城农业科技发展有限公司 Preparation method and application of essential oil composition for soothing nerves, helping sleep and recovering memory

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CN105213541A (en) * 2015-09-29 2016-01-06 宗欣生态科技(上海)有限公司 Rose compound essential oil improving insomnia due to pressure and preparation method thereof
CN105213541B (en) * 2015-09-29 2019-03-19 宗欣生态科技(上海)有限公司 Improve the Rose compound essential oil and preparation method thereof of insomnia due to pressure
CN106880709A (en) * 2017-03-30 2017-06-23 厦门正合意生物科技有限公司 A kind of relieving insomnia for improving brain wave helps the composite essential oil of sleep
CN107144685A (en) * 2017-05-27 2017-09-08 无限极(中国)有限公司 A kind of screening technique with refreshing effect essential oil or its product
CN107144685B (en) * 2017-05-27 2018-11-09 无限极(中国)有限公司 A kind of screening technique with refreshing effect essential oil or its product
EP3485894A1 (en) * 2017-11-20 2019-05-22 Italfarmaco SpA Combination of officinal plants and their use in the treatment and/or prevention of sleep disorders
CN110292573A (en) * 2019-06-12 2019-10-01 颇黎芳香医药科技(上海)有限公司 A kind of relieve stagnation sleeping compound essential oil
CN110292573B (en) * 2019-06-12 2022-07-22 颇黎芳香医药科技(上海)有限公司 Depression-relieving and sleep-aiding compound essential oil
CN111317753A (en) * 2020-03-11 2020-06-23 北京茂思商贸有限公司 Plant essential oil composition with effects of calming and helping sleep and preparation method thereof
CN112121095A (en) * 2020-08-19 2020-12-25 歌曼丽(苏州)大健康产业发展有限公司 Hypnotic essential oil composition with quick response and preparation method thereof
CN111973672A (en) * 2020-09-11 2020-11-24 杜浩 Sleep-aiding composition and preparation method thereof
CN113604280A (en) * 2021-07-19 2021-11-05 上海应用技术大学 Lavender compound essential oil, preparation method and evaluation method thereof
CN114129630A (en) * 2021-11-22 2022-03-04 河北泰城农业科技发展有限公司 Preparation method and application of essential oil composition for soothing nerves, helping sleep and recovering memory

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