CN104739891A - Pet dog health product with function of adjusting lipid metabolism - Google Patents
Pet dog health product with function of adjusting lipid metabolism Download PDFInfo
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- CN104739891A CN104739891A CN201510088551.2A CN201510088551A CN104739891A CN 104739891 A CN104739891 A CN 104739891A CN 201510088551 A CN201510088551 A CN 201510088551A CN 104739891 A CN104739891 A CN 104739891A
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Abstract
The invention discloses a pet dog health product with a function of adjusting lipid metabolism, and belongs to the fields of animal husbandry, veterinary medicine and breeding industry. The pet dog health product is composed of the following ingredients in percentage by weight: 40-45% of L-carnitine, 0.5-1% of chromium yeast, 14-18% of chitosan oligosaccharide, 20-25% of milk powder, 10-14% of starch, 2-4% of beef flavour and 0.5-1% of calcium stearate. The pet dog health product disclosed by the invention is used for adjusting lipid metabolism through multiple mechanisms and multiple phases, overcomes the shortages of the existing products, and is beneficial to improving the lipid metabolism of the body, thus reducing the accumulation of fats in the body; the pet dog health product has a high application value, and prevention and treatment functions on the obesity and the complication diseases thereof of pet dogs to a certain extend, thus improving the living quality of the pet dogs and reducing the financial burdens of dog keepers.
Description
Technical field
The invention belongs to animal and veterinary aquaculture field, particularly a kind of have the pet dog health product regulating lipid metabolism function.
Background technology
In recent years, the problem of obesity of dog cat was paid close attention to day by day widely, and research thinks that the pathogenesis of dog obesity and disorders of lipid metabolism have substantial connection, and main mechanism is that lipid anabolism strengthens and lipidolysis metabolism weakens.In developed country, obesity has become the modal nutritional disease of a kind of dog, there are many survey reports, although according to the difference of place and standard, but the incidence rate of dog obesity is totally 22%-44%, and most of investigation personnel unanimously think, 33% is had at least to be fat to the dog that veterinary clinic is medical, and constantly increase the same with the incidence rate of human obesity, the fat incidence rate of dog is also increasing day by day.Fat also comprise with numerous disease that the life-span reduces, osteoarthritis, respiratory distress, glucose intolerance and diabetes, hypertension, thermostability decline, have difficult labour, the cancer of some type, to increase the risk of anaesthetizing and postoperative complication etc. relevant, have a strong impact on the quality of life of pet dog, add financial burden and the emotion puzzlement of dog owner.
At present, the management of fat dog is mainly taked always to the way reducing Energy intaking (dietary management) and increase energy expenditure (motion).Although it is also very effective for implementing these ways comprehensively and early, overcome the fat impact on behavior, society, metabolism etc. of dog may be quite difficult.Also do not have the safe compounds can preventing and treating dog obesity at present, can the regulate compound of lipid metabolism or the agent of compound recipe group of therefore studying novel safety become the focus of concern.
Summary of the invention
Primary and foremost purpose of the present invention is to overcome the shortcoming that exists in prior art with not enough, provides a kind of and has the pet dog health product regulating lipid metabolism function.
Object of the present invention is achieved through the following technical solutions: a kind of have the pet dog health product regulating lipid metabolism function, is grouped into: VBT 40% ~ 45%, yeast chromium 0.5% ~ 1%, oligochitosan 14% ~ 18%, milk powder 20% ~ 25%, starch 10% ~ 14%, beef flavor 2% ~ 4% and calcium stearate 0.5% ~ 1% by the one-tenth of following percentage meter by weight.
Preferably, the described pet dog health product with adjustment lipid metabolism function are grouped into by the one-tenth of following percentage meter by weight: VBT 42%, yeast chromium 0.5%, oligochitosan 17%, milk powder 23%, starch 12.5%, beef flavor 4% and calcium stearate 1%.
The described pet dog health product regulating lipid metabolism function that have can be any dosage form, preferably oral liquid, tablet, capsule, granule or feed additive etc.
VBT, also known as carnitine, is a kind of amino acid derivativges, and its Main Function helps long-chain fatty acid to enter the sole support that mitochondrion carries out beta oxidation.Can beta oxidation be promoted, reduce the concentration of triglyceride in blood and tissue, improve the Power supply of lipidosis animal.In addition, VBT can be used as the free radical produced in antioxidant for clearing body, reduces over oxidative damage, and then reduces for snperoxiaized lipid quantity.
Blood Cholesterol level is mainly safeguarded in yeast chromium effect, affect the synthesis of metabolism of lipid and cholesterol in animal livers and removing, promote the code reassignment of fat and the hydrolysis of fatty tissue, improve blood high-density lipoprotein concentration, suppress cholesterol in serum level.
Oligochitosan can reduce the concentration of triglyceride and cholesterol in blood, reduces content and the gene expression amount thereof of triglyceride levels and fatty acid synthetase in liver, reduces cholesterol and fatty acid absorption, thus improve lipid metabolism.
The preparation method (for tablet) of described pet dog health product, comprise the steps: to get VBT 40% ~ 45%, yeast chromium 0.5% ~ 1%, oligochitosan 14% ~ 18%, milk powder 20% ~ 25%, starch 10% ~ 14%, beef flavor 2% ~ 4%, mix homogeneously with calcium stearate 0.5% ~ 1% after crossing 80 mesh sieves respectively, tablet machine is prepared, obtains pet dog troche of health products.
The present invention has following advantage and effect relative to prior art: pet care product of the present invention are a kind of by number of mechanisms, multiple link adjustment lipid metabolism, overcome the deficiency of existing product, be conducive to improving body lipid metabolism, thus minimizing fat is piled up in vivo, there is larger using value, to the obesity of pet dog and complication thereof, there is certain preventive and therapeutic action, thus improve the quality of life of pet dog, alleviate the financial burden of dog owner.
Accompanying drawing explanation
Fig. 1 is the preparation method flow chart with the tablet of the pet dog health product regulating lipid metabolism function of embodiment 1;
Fig. 2 is that the pet dog troche of health products of embodiment 3 affects result figure to target animals body weight.
Detailed description of the invention
Below in conjunction with embodiment and accompanying drawing, the present invention is described in further detail, but embodiments of the present invention are not limited thereto.
Embodiment 1
Get VBT 420g, yeast chromium 5g, oligochitosan 170g, milk powder 230g, starch 125g and beef flavor 40g, cross 80 mesh sieves respectively, mixing, add calcium stearate 10g, stir, automatic tableting press makes tablet according to a conventional method, is total to obtain health product 1666, the heavy 0.6g of average sheet.
Embodiment 2
Target animals safety testing
1. animal grouping and feeding and management
Grow up Beagle dog 10 (Jiangsu Province's house pet Breeding Center provides), male and female half and half, 3 years old ~ 5 years old age, body weight 9kg ~ 15kg, Animal Lab. room temperature (22 ± 5) DEG C, humidity 60% ~ 80%.10 Beagle dogs are divided into 2 groups at random according to body weight: matched group and test group.Control group fed basal diet; Test group is fed basal diet, and supplements pet dog health product 2 slices/day.Testing the full phase only adopts single cage to feed to all tested dogs, at regular time and quantity, freely drinks water.Feed period 60 days, each group feeding and management method is identical.
2. sign Index measures
Duration of test, observes every day such as situation of searching for food, the mental status, clinical three number (temperature pulse respiration numbers) change and defecation situations etc., and does itemized record, and experiment terminates to carry out Mathematical Statistics Analysis to experimental result afterwards.
3. hematological indices measures
Taking a blood sample respectively in test end, adopts full-automatic blood cell analysis machine to measure the indexs such as RBC number, leukocyte count, platelet count and hemoglobin content.
4. blood parameters measures
Taking a blood sample respectively in test end, uses M149928-fully-automatic dry type biochemistry analyzer to measure total serum protein, albumin, total bilirubin, serum alanine aminotransferase, aspartate amino transferase, alkali phosphatase, blood urea nitrogen and creatinine equal size.
5. date processing SPSS17.0, single factor test variance carries out statistical analysis, and each group data all represent with mean+SD.
6. results and analysis
The mensuration of 6.1 sign Indexes
Matched group and prescription grain group before the test after sign Index without significant change, all normally.Honey stomach, search for food very fast, the mental status is active, and clinical three numbers are normal, and feces is normal without diarrhoea and constipation, smooth submissive by hair.
The mensuration of 6.2 hematological indices
Result shows, the erythrocyte of test group and hemoglobin content are all micro-higher than matched group, but no significant difference (P>0.05), and the leukocyte count of test group and neutrophil number are higher than matched group (P<0.05), show that this prescription grain can improve its Abwehrkraft des Koepers.
The measurement result of table 1 hematological indices
Note: * represents and compares P<0.05 with matched group.
6.3 blood parameters measurement results
The measurement result of table 2 blood parameters
Result shows, the liver function biochemical indicator of test group and matched group and renal function biochemical indicator no significant difference, shows the vitals not damaged effect such as liver, kidney of these pet dog health product to target animals.
The safety testing of these pet dog health product shows, obvious malaise symptoms does not appear in target animals, and to Liver and kidney without obvious damaging action, therefore, these pet dog health product are products of safety non-toxic, can life-time service.
Embodiment 3
The pet dog health product of embodiment 1 are to the effect test of target animals
1. laboratory animal and test method
Grow up Beagle dog 10 (Jiangsu Province's house pet Breeding Center provides), male and female half and half, 3 ~ 5 years old age, Animal Lab. room temperature (22 ± 5) DEG C, humidity 60% ~ 80%.Feed 90 days with autogamy high lipid food (15g duck oil+80g normal feedstuff+5g yolk powder), a dog body weight 14kg ~ 21kg, sets up obesity models.10 Beagle dogs are divided into 2 groups at random according to body weight: matched group and test group.Control group fed basal diet; Test group is fed basal diet, and supplements health product 2 slices/day.Testing the full phase only adopts single cage to feed to all tested dogs, at regular time and quantity, freely drinks water.Feed period 60 days, feeding and management method is identical.
2. body weight determination
L days before testing, after test, 7d, 15d, 30d, 60d measure body weight respectively, and calculate its increment size changed relative to original body mass (body weight of the front 1d of test), increment size=(measuring body weight/original body mass) × 100%.
3. on the impact of blood fat metabolism
Take a blood sample respectively in before test and test end, separation of serum, measures correlation values.Serum triglycerides (TG), T-CHOL (Chol), high density lipoprotein (HDL), low density lipoprotein, LDL (LDL) content automatic clinical chemistry analyzer measure.Serum glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) and malonaldehyde (MDA) content, measure with 722 grating spectrophotometers.Measuring test kit is that Bioengineering Research Institute's product is built up in Nanjing.
4. all data SPSS17.0 software one factor analysis of variance method (ANOVA) carry out the statistical analysis of group difference, and each group data all represent with mean+SD.
5. results and analysis
5.1 pet dog health product are on the impact of target animals body weight
As shown in Figure 2, a dog body weight for test group is reduction trend, after experiment 15d ~ 30d to result, underspeeds the fastest, with matched group significant difference (P<0.05).Show, these pet dog health product have the effect of fat-reducing.
5.2 impacts on blood fat metabolism
Result is as shown in table 3, as can be seen from Table 3, this pet dog health product can reduce the content (P<0.05) of serum triglycerides in blood (TG), T-CHOL (Chol) and low density lipoprotein, LDL (LDL), improve high density lipoprotein (HDL) content (P<0.05), promote the metabolism of blood fat, reduce blood lipid level; The activity of blood Glutathione Peroxidase (GSH-Px) and superoxide dismutase (SOD) can be promoted simultaneously, reduce malonaldehyde (MDA) content (P<0.05) in blood, the oxidation resistance of intensifier target animal, reduces lipid peroxidation.
This test shows, these pet dog health product can promote the blood lipid metabolism of dog, improves antioxidant ability of organism and resistance, improves the symptom of obesity and complication thereof.Therefore the lipid metabolism of this pet dog health product to dog has immunoregulation function, improves its quality of life.
The pet dog health product of the present invention's development are applied to 41 routine fat dogs, and through the clinical observation of feeding of 1 year, result showed that the dog of 87.8% is only respond well, and lose weight, blood lipid metabolism improves, and has certain health-care effect.
The testing result of table 3 blood fat metabolism
Note: different lower case represents that colleague compares P<0.05.
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from spirit of the present invention and principle, substitute, combine, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.
Claims (3)
1. one kind has the pet dog health product regulating lipid metabolism function, it is characterized in that, be grouped into by the one-tenth of following percentage meter by weight: VBT 40% ~ 45%, yeast chromium 0.5% ~ 1%, oligochitosan 14% ~ 18%, milk powder 20% ~ 25%, starch 10% ~ 14%, beef flavor 2% ~ 4% and calcium stearate 0.5% ~ 1%.
2. according to claim 1 have the pet dog health product regulating lipid metabolism function, it is characterized in that, described having regulates the pet dog health product of lipid metabolism function to be grouped into by the one-tenth of following percentage meter by weight: VBT 42%, yeast chromium 0.5%, oligochitosan 17%, milk powder 23%, starch 12.5%, beef flavor 4% and calcium stearate 1%.
3. the pet dog health product with adjustment lipid metabolism function described in claim 1 or 2 are oral liquid, tablet, capsule, granule or feed additive.
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| CN201510088551.2A CN104739891A (en) | 2015-02-26 | 2015-02-26 | Pet dog health product with function of adjusting lipid metabolism |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107242376A (en) * | 2017-05-31 | 2017-10-13 | 江苏农牧科技职业学院 | It is a kind of to prevent and treat the fat feed of pet and preparation method |
| CN107581382A (en) * | 2017-10-13 | 2018-01-16 | 湖北聚注通用技术研究有限公司 | A kind of feed for pet filler with effect of weight reducing |
| CN108260731A (en) * | 2017-01-03 | 2018-07-10 | 江苏益力达生物科技有限公司 | A kind of nutritive cream for controlling pet dog cat weight |
| CN110720550A (en) * | 2018-12-27 | 2020-01-24 | 瑞普（天津）生物药业有限公司 | Snack capable of reducing blood fat of pets and preparation method of snack |
| CN111165676A (en) * | 2020-01-13 | 2020-05-19 | 青岛博隆实验动物有限公司 | Additive for colostrum substitute of puppy, preparation method and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103238732A (en) * | 2013-04-30 | 2013-08-14 | 江苏畜牧职业技术学院 | Pet dog food used for health care of adult sterilized female dogs and preparation method of pet dog food |
-
2015
- 2015-02-26 CN CN201510088551.2A patent/CN104739891A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103238732A (en) * | 2013-04-30 | 2013-08-14 | 江苏畜牧职业技术学院 | Pet dog food used for health care of adult sterilized female dogs and preparation method of pet dog food |
Non-Patent Citations (2)
| Title |
|---|
| 王俊东等: "《畜禽营养代谢与中毒病》", 31 October 2001, 中国林业出版社 * |
| 谷继承等: "《饲料添加剂研究与应用进展》", 31 December 2008, 中国农业科学技术出版社 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108260731A (en) * | 2017-01-03 | 2018-07-10 | 江苏益力达生物科技有限公司 | A kind of nutritive cream for controlling pet dog cat weight |
| CN107242376A (en) * | 2017-05-31 | 2017-10-13 | 江苏农牧科技职业学院 | It is a kind of to prevent and treat the fat feed of pet and preparation method |
| CN107581382A (en) * | 2017-10-13 | 2018-01-16 | 湖北聚注通用技术研究有限公司 | A kind of feed for pet filler with effect of weight reducing |
| CN110720550A (en) * | 2018-12-27 | 2020-01-24 | 瑞普（天津）生物药业有限公司 | Snack capable of reducing blood fat of pets and preparation method of snack |
| CN111165676A (en) * | 2020-01-13 | 2020-05-19 | 青岛博隆实验动物有限公司 | Additive for colostrum substitute of puppy, preparation method and application |
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Application publication date: 20150701 |