CN104721728A - Gel for treating acne and preparation method thereof - Google Patents
Gel for treating acne and preparation method thereof Download PDFInfo
- Publication number
- CN104721728A CN104721728A CN201310718334.8A CN201310718334A CN104721728A CN 104721728 A CN104721728 A CN 104721728A CN 201310718334 A CN201310718334 A CN 201310718334A CN 104721728 A CN104721728 A CN 104721728A
- Authority
- CN
- China
- Prior art keywords
- preparation
- acne
- emulsifiable paste
- acne treatment
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a gel for treating acne and a preparation method thereof. The preparation comprises the following raw materials in parts by weight: 30% of dried rehamnnia root, 6% of cortex moutan, 8% of root of common peony, 15% of dandelion, 7% of manyleaf paris rhizome, 8% of selfheal, 6% of sea-tangle, 6% of seaweed, 6% of fried rhizoma sparganii, and 8% of fried curcuma zedoary. The gel for treating the acne is simple and available in the components, simple in preparation method operation, and scientific and reasonable in formula and various Chinese herbal medicinal ingredients supplement each other; the preparation is low in production cost, large in drug-loading rate, good in drug release degree, non-toxic and non-stimulation, good in curative effect, short in course of treatment, convenient to use and wide in application future.
Description
Technical field
The invention belongs to field of medicine preparations, be specifically related to gel of a kind of Acne treatment and preparation method thereof.
Background technology
Sense of loving to make up and wearing beautiful clothes, everybody has it, and particularly at life's full flowering teenager is advocated especially and chased after U.S., can wilfully this age has many juvenile men and women all to overgrow with worried acne, the body and mind of the vast teenager men and women that frustrates.Acne is that the chronic inflammatory skin of a kind of hair follicle and sebaceous gland is sick, frequently-occurring disease is in adolescence, modern medicine study thinks that acne is under the condition of inherited genetic factors, and effect two the aspect factors increasing the microorganisms such as the corynebacterium acnes in (dihydrotestosterone especially in skin histology is increased) and follicular orifice due to androgen secretion cause.The traditional Chinese medical science thinks face nose and thoracic dorsal subordinate lung, causes the reason of acne to be hinder caused by the skin by wind and heat in the lung meridian; Or because of surfeit delicious food, greasy, maror, taste intrinsic heat, damp and hot interior life, fumigates and forms in face.Medically effective Therapeutic Method be there is no to acne at present, the defects such as mainly use the western medicines such as tetracycline, metronidazole, dimension A acid, there is uncertain therapeutic efficacy cuts, and the course for the treatment of is long, large, the easy recurrence of side effect.
Current China medical science, beauty treatment release the product much controlling acne, but curative effect is remarkable, and a lot of medicine can only mitigate the disease and lack effective treatment means, and medical expense is high and easily recur.Present inventor through reading over and study a series of Chinese medicine and pharmacy data, by formula repeatedly, draws gel of a kind of Acne treatment of the present invention and preparation method thereof.
Summary of the invention
The present invention aims to provide that a kind of medical expense is low, good effect, non-stimulated, gel of Acne treatment of having no side effect and preparation method thereof.
For achieving the above object, gel of a kind of Acne treatment of the present invention and preparation method thereof, its specific embodiments is:
Emulsifiable paste of a kind of Acne treatment of the present invention and preparation method thereof, it is characterized in that, said preparation parts by weight percentages is: Radix Rehmanniae 1-50%, Cortex Moutan 1-10%, Radix Paeoniae Rubra 1-10%, Herba Taraxaci 1-20%, Rhizoma Paridis 1-10%, Spica Prunellae 1-10%, Thallus Laminariae (Thallus Eckloniae) 1-10%, Sargassum 1-10%, fries Rhizoma Sparganii 1-10%, fries Rhizoma Curcumae 1-10%.
Emulsifiable paste of a kind of Acne treatment of the present invention and preparation method thereof, is characterized in that, said preparation parts by weight percentages is: Radix Rehmanniae 30%, Cortex Moutan 6%, Radix Paeoniae Rubra 8%, Herba Taraxaci 15%, Rhizoma Paridis 7%, Spica Prunellae 8%, Thallus Laminariae (Thallus Eckloniae) 6%, Sargassum 6%, fries Rhizoma Sparganii 6%, fries Rhizoma Curcumae 8%.
Emulsifiable paste of a kind of Acne treatment of the present invention and preparation method thereof, is characterized in that, the preparation method of this Chinese medicine preparation is:
(1) extraction process: the 10 taste medical materials such as Radix Rehmanniae are decocted with water, decocting time 0.5-3h, add water multiple 6-15 doubly, decoct number of times 1-4 time;
(2) process for refining: decoction liquor is concentrated into solid-liquid ratio 0.5-2, regulate determining alcohol to 60-85% after adding ethanol, dark place leaves standstill 10-36h, filters, and reclaims ethanol, is concentrated into thick paste, density 1.05(40-60 DEG C), dry, pulverize 80 mesh sieves, for subsequent use;
(3) be dispersed in 500-1000ml water by Carbomer-940 5-20g, swelling, placement is spent the night, and adjusts pH to 4-7, obtain water white bare substrate with triethanolamine;
(4) extractum is pulverized 200 mesh sieves, be dissolved in 20-50g ethanol, then add propylene glycol 20-60g mix homogeneously;
(5) under 100-300r/min condition, by 2) slowly add 1) in stir, to obtain final product.
Emulsifiable paste of a kind of Acne treatment of the present invention and preparation method thereof, is characterized in that said preparation preparation process (1) decocting time 2h, the multiple 10 times that adds water, decocts number of times 3 times.
Emulsifiable paste of a kind of Acne treatment of the present invention and preparation method thereof, is characterized in that said preparation preparation process (2) solid-liquid ratio 1:1.5, determining alcohol 80%, leaves standstill 30h.
Emulsifiable paste of a kind of Acne treatment of the present invention and preparation method thereof, is characterized in that said preparation substrate used is one or more in carbomer, propylene glycol, triethanolamine, sodium hydroxide, ethanol, glycerol, sodium carboxymethyl cellulose.
Key component pharmacology analysis of the present invention:
Radix Rehmanniae, nature and flavor: sweetness and bitterness are cool.Enter the heart, liver, kidney channel.Clearing away heat and promoting production of body fluid YIN nourishing, nourishes blood.
Cortex Moutan, arduous; Cool; Be slightly cold, the heart; Liver; Kidney; Lung meridian, heat clearing away; Promoting blood circulation to remove blood stasis.
Radix Paeoniae Rubra, bitter, be slightly cold.Return Liver Channel.Clearing away heat and cooling blood; Blood circulation promoting and blood stasis dispelling.
Herba Taraxaci, bitter, sweet, cold.Return Liver Channel, stomach warp.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.
Rhizoma Paridis, toil, cold, poisonous.Enter the heart, Liver Channel.Heat-clearing and toxic substances removing, antiasthmatic-antitussive, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.
Spica Prunellae, bitter, acrid, cold.Enter liver, gallbladder meridian.There is purging liver-fire, resolving depression eliminating stagnation, subduing swelling and detoxicating effect.
Thallus Laminariae (Thallus Eckloniae) is salty; Cold; Nontoxic.Return liver, stomach, kidney channel.Eliminating phlegm and softening indurated mass; Diuretic detumescent.
Sargassum is bitter in the mouth, salty, cold in nature, nontoxic.Return lung; Spleen; Kidney; Liver stomach warp.Effect: softening the hard mass; Expectorant; Diuretic; Detumescent.
Fry Rhizoma Sparganii, toil, flat, enter liver, spleen channel.Removing blood stasis, circulation of qi promoting, removing food stagnancy, pain relieving.
Fry Rhizoma Curcumae, pungent, bitter, temperature.Return liver, spleen channel.There is circulation of qi promoting removing blood stasis, removing food stagnancy analgesic efficacy.
For investigating clinical efficacy and the safety of medicine of the present invention further, 100 routine patients with acne are selected to carry out clinical observation to the curative effect of medicine of the present invention.
All cases with the diagnostic criteria of " modern dermatological ", " Surgery of Chinese Medicine " and People's Republic of China's industry standard " TCM Dermatology disease Standardization of diagnosis and curative effect " acne vulgaris and syndrome for foundation:
1. be more common in person between twenty and fifty, be apt to occur in seborrhea position.Skin lesion is hoary hair or blackhead, inflamed papules, pus head, and severe patient can nodosity, cyst.
2. have eating and drinking without temperance more, the pungent delicious food savoury of surfeit and bringing out.
3. women increases with menoxenia or premenstrual skin lesion and increases the weight of.
Therapeutic Method:
Treatment group: use medicine of the present invention, 1-2 time on the one, after first being dried by affected part warm water cleaning, is evenly coated with and puts one deck on the skin, cleaned in affected part after using 0.5-1h.
Acne curative effect determinate standard: with reference to People's Republic of China's industry standard " TCM Dermatology disease Standardization of diagnosis and curative effect ":
Clinical recovery: skin lesion all disappears, only leaves pigmentation and scar scar person.
Effective: skin lesion disappears more than 70%, or the order of severity lowers more than 2 degree.
Effective: skin lesion disappears 30 ~ 70%, or the order of severity lowers more than 1 degree, still has the new skin lesion person of appearance.
Invalid: skin lesion disappears below 30%, or add severe one.
Therapeutic outcome: recovery from illness 88 example, effective 8 examples, effective 4 examples, invalid 0 example.
Clinical trial results proves, instant effect of the present invention, effective percentage reaches 100%.
Chinese medicine preparation of the present invention has the following advantages compared to other prescription preparation:
1. component is simple and easy to get, and preparation method is easy and simple to handle.
2. compatibility is rigorous, scientific and reasonable, and plurality of Chinese composition complements each other, and can regulate organism endocrine, maintains hormone in vivo balance, promotes sebum metabolism.
3. said preparation cost is low, drug loading large, good, the nontoxic nonirritant of release, and good effect, short treating period, easy to use, application prospect is extensive.
Detailed description of the invention
Embodiment is only for further illustrating the present invention below, does not limit the present invention in any form.
embodiment 1
Prescription: Radix Rehmanniae 30%, Cortex Moutan 6%, Radix Paeoniae Rubra 8%, Herba Taraxaci 15%, Rhizoma Paridis 7%, Spica Prunellae 8%, Thallus Laminariae (Thallus Eckloniae) 6%, Sargassum 6%, fries Rhizoma Sparganii 6%, fries Rhizoma Curcumae 8%.
Preparation method:
(1) extraction process: the 10 taste medical materials such as Radix Rehmanniae are decocted with water, decocting time 0.5-3h, add water multiple 6-15 doubly, decoct number of times 1-4 time;
(2) process for refining: decoction liquor is concentrated into solid-liquid ratio 0.5-2, regulate determining alcohol to 60-85% after adding ethanol, dark place leaves standstill 10-36h, filters, and reclaims ethanol, is concentrated into thick paste, density 1.05(40-60 DEG C), dry, pulverize 80 mesh sieves, for subsequent use;
(3) be dispersed in 500-1000ml water by Carbomer-940 5-20g, swelling, placement is spent the night, and adjusts pH to 4-7, obtain water white bare substrate with triethanolamine;
(4) extractum is pulverized 200 mesh sieves, be dissolved in 20-50g ethanol, then add propylene glycol 20-60g mix homogeneously;
(5) under 100-300r/min condition, by 2) slowly add 1) in stir, to obtain final product.
embodiment 2
Prescription: Radix Rehmanniae 30%, Cortex Moutan 6%, Radix Paeoniae Rubra 8%, Herba Taraxaci 15%, Rhizoma Paridis 7%, Spica Prunellae 8%, Thallus Laminariae (Thallus Eckloniae) 6%, Sargassum 6%, fries Rhizoma Sparganii 6%, fries Rhizoma Curcumae 8%.
Preparation method:
(1) extraction process: the 10 taste medical materials such as Radix Rehmanniae are decocted with water, decocting time 2h, the multiple 10 times that adds water, decoction number of times 3 times;
(2) process for refining: decoction liquor is concentrated into solid-liquid ratio 1:1.5, regulate determining alcohol to 80% after adding ethanol, dark place leaves standstill 30h, filters, and reclaims ethanol, is concentrated into thick paste, density 1.05(40-60 DEG C), dry, pulverize 80 mesh sieves, for subsequent use;
(3) be dispersed in 500-1000ml water by Carbomer-940 5-20g, swelling, placement is spent the night, and adjusts pH to 4-7, obtain water white bare substrate with triethanolamine;
(4) extractum is pulverized 200 mesh sieves, be dissolved in 20-50g ethanol, then add propylene glycol 20-60g mix homogeneously;
(5) under 100-300r/min condition, by 2) slowly add 1) in stir, to obtain final product.
Claims (6)
1. the emulsifiable paste and preparation method thereof of an Acne treatment, it is characterized in that, said preparation parts by weight percentages is: Radix Rehmanniae 1-50%, Cortex Moutan 1-10%, Radix Paeoniae Rubra 1-10%, Herba Taraxaci 1-20%, Rhizoma Paridis 1-10%, Spica Prunellae 1-10%, Thallus Laminariae (Thallus Eckloniae) 1-10%, Sargassum 1-10%, fries Rhizoma Sparganii 1-10%, fries Rhizoma Curcumae 1-10%.
2. the emulsifiable paste and preparation method thereof of 1 one kinds of Acne treatments according to claim, it is characterized in that, said preparation parts by weight percentages is: Radix Rehmanniae 30%, Cortex Moutan 6%, Radix Paeoniae Rubra 8%, Herba Taraxaci 15%, Rhizoma Paridis 7%, Spica Prunellae 8%, Thallus Laminariae (Thallus Eckloniae) 6%, Sargassum 6%, fries Rhizoma Sparganii 6%, fries Rhizoma Curcumae 8%.
3. the emulsifiable paste and preparation method thereof of a kind of Acne treatment according to claim 1, it is characterized in that, the preparation method of this Chinese medicine preparation is:
(1) extraction process: the 10 taste medical materials such as Radix Rehmanniae are decocted with water, decocting time 0.5-3h, add water multiple 6-15 doubly, decoct number of times 1-4 time;
(2) process for refining: decoction liquor is concentrated into solid-liquid ratio 0.5-2, regulate determining alcohol to 60-85% after adding ethanol, dark place leaves standstill 10-36h, filters, and reclaims ethanol, is concentrated into thick paste, density 1.05(40-60 DEG C), dry, pulverize 80 mesh sieves, for subsequent use;
(3) be dispersed in 500-1000ml water by Carbomer-940 5-20g, swelling, placement is spent the night, and adjusts pH to 4-7, obtain water white bare substrate with triethanolamine;
(4) extractum is pulverized 200 mesh sieves, be dissolved in 20-50g ethanol, then add propylene glycol 20-60g mix homogeneously;
(5) under 100-300r/min condition, by 2) slowly add 1) in stir, to obtain final product.
4. the emulsifiable paste and preparation method thereof of a kind of Acne treatment according to claim 3, is characterized in that said preparation preparation process (1) decocting time 2h, the multiple 10 times that adds water, decocts number of times 3 times.
5. the emulsifiable paste and preparation method thereof of a kind of Acne treatment according to claim 3, is characterized in that said preparation preparation process (2) solid-liquid ratio 1:1.5, determining alcohol 80%, leaves standstill 30h.
6. the emulsifiable paste and preparation method thereof of a kind of Acne treatment according to claim 3, is characterized in that said preparation substrate used is one or more in carbomer, propylene glycol, triethanolamine, sodium hydroxide, ethanol, glycerol, sodium carboxymethyl cellulose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310718334.8A CN104721728A (en) | 2013-12-24 | 2013-12-24 | Gel for treating acne and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310718334.8A CN104721728A (en) | 2013-12-24 | 2013-12-24 | Gel for treating acne and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104721728A true CN104721728A (en) | 2015-06-24 |
Family
ID=53446524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310718334.8A Pending CN104721728A (en) | 2013-12-24 | 2013-12-24 | Gel for treating acne and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104721728A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107334713A (en) * | 2017-06-22 | 2017-11-10 | 芜湖福民生物药业股份有限公司 | Phosphocholine modified acne eliminating cream and preparation method thereof |
-
2013
- 2013-12-24 CN CN201310718334.8A patent/CN104721728A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107334713A (en) * | 2017-06-22 | 2017-11-10 | 芜湖福民生物药业股份有限公司 | Phosphocholine modified acne eliminating cream and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108969642A (en) | A kind of Chinese medicine compound prescription external preparation that treating chronic prostatitis and its preparation process | |
| CN105030620A (en) | Moisturizing and acne removing facial cleanser and preparing method thereof | |
| CN103893613B (en) | A kind of medicine treating oral ulcer and preparation method | |
| CN103919966B (en) | A kind of medicine treating acne | |
| CN102349976A (en) | Traditional Chinese medicine for treating insomnia | |
| CN104042981A (en) | Medicament for treating postnatal constipation and preparation method thereof | |
| CN104721728A (en) | Gel for treating acne and preparation method thereof | |
| CN102302655B (en) | Loquat acne removing capsules | |
| CN106822300B (en) | Traditional Chinese medicine preparation for removing acne and beautifying face | |
| CN104055959A (en) | Traditional Chinese medicine lotion and nursing method for treating gastrointestinal dampness-heat type seborrhoeic dermatitis | |
| CN104840507A (en) | Chinese medicinal ointment for treating face acne or comedo and preparation method | |
| CN108888660A (en) | A kind of low irritant drug and preparation method thereof for treating acne or acne rosacea | |
| CN107412686A (en) | A kind for the treatment of whelk Chinese medicine preparation containing motherwort | |
| CN104721727A (en) | Emulsifiable paste for treating acne and preparation method thereof | |
| CN105770848A (en) | Chilblain ointment containing extract from bitter gourd vines and leaves and preparation method thereof | |
| CN103330669A (en) | Traditional Chinese medicine acne-removing mask and preparation method thereof | |
| CN109793827A (en) | A kind of pharmaceutical composition that treating psoriasis, its preparation and preparation method | |
| CN104435153A (en) | Traditional Chinese medicine composition for treating hypertension and preparation method | |
| CN107551222A (en) | A kind for the treatment of whelk Chinese medicine preparation containing peppermint | |
| CN113577137A (en) | Traditional Chinese medicine composition for treating acne and preparation method and application thereof | |
| CN101376015B (en) | Sperm-stopping formulation for treating spermatorrhea and preparation method thereof | |
| CN102512608A (en) | Traditional Chinese medicinal preparation for treating repeated and intermittent light epistaxis and preparation method | |
| CN103381240A (en) | Wind-dispelling coolant and application of same in drug for treating contact dermatitis | |
| CN108514632A (en) | A kind of Chinese medicine composition and preparation method thereof for treating chloasma | |
| CN109876077A (en) | A kind of powdered medicine for coaptation and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150624 |