CN104721569A - Preparation for clearing away heart fire and relieving restlessness of insomniacs and preparation method of preparation - Google Patents
Preparation for clearing away heart fire and relieving restlessness of insomniacs and preparation method of preparation Download PDFInfo
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Abstract
The invention discloses a preparation for clearing away heart fire and relieving restlessness of insomniacs. The preparation is prepared from the following main raw materials in parts by mass: 10-15 parts of tuber fleeceflower stem, 8-13 parts of licorice root, 12-16 parts of herb of javan waterdropwort, 13-18 parts of clematis filamentosa dunn, 12-16 parts of Indian buead, 10-14 parts of common aeschynomene herb, 11-15 parts of herb of hairystalk loosestrife, 18-23 parts of lily, 16-20 parts of salvia miltiorrhiza, 14-16 parts of motherwort fruit, 11-16 parts of orchid, 12-15 parts of aizoon stonecrop herb, 8-17 parts of all-grass of repent pellionia, 12-16 parts of all-grass of smallleaf ziziphora, 9-13 parts of root or stem of curious kadsura and 13-18 parts of root of Chinese winterhazel. The preparation has the effects of nourishing the brain to soothe the nerves, reducing internal heat to relieve intestinal stasis, soothing the liver to regulate qi, removing meridian obstruction to promote blood circulation and calming for peaceful sleeping, and can effectively eliminate symptoms of insomnia, depression, dysphoria, mental disorders and the like.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly a kind of insomniac clears away heart-fire relieving restlessness preparation and preparation method.
Background technology
Insomnia refers to fall asleep and maybe cannot keep sleep state, causes not having enough sleep.Also known as DIMS (DlMS), it is modal disease in sleep disorder.Insomnia for a variety of causes cause that difficulty falling asleep, Depth of sleep or frequency are too short, early awakening and the length of one's sleep deficiency or of poor quality etc.Clinical can not sleep again after easily waking up after not easily falling asleep, sleeping, waking up, sometimes sleeping and sometimes waking, easily waken up with a start, to sound or light sensitivity, or be insomnia for feature all night, and often with lassitude, bradykinesia, fatigue and asthenia, vexed annoyance in the daytime, have a strong impact on physical and mental health and work, studying and living.Have a sleepless night mainly spiritual to the injury of human body, generally can not be fatal.But chronic insomnia can make people short-tempered, aggressivity is strong, and hypomnesis is absent minded, mental fatigue.Insomnia easily causes organic disease to the spiritual impact of people, also can make people's immunity degradation, the health consumption making people is comparatively large because the secretion of auxin mainly sleeping at night after, therefore the insomnia of children can reduce the secretion of auxin, is unfavorable for the growth promoter of health.Insomnia can cause the feeling of fatigue of people, uneasiness, general malaise, listless, delay of response, headache, memory not to concentrate, and seriously a bit can cause schizophrenia.
The traditional Chinese medical science is thought because temperament and interest hindered, depression of liver-QI, and heart-fire is partially high, and qi depression to blood stasis is disturbed in phlegm-fire, and disorder of stomach-QI causes zang-fu organs qi movement lifting imbalance, negative and positive Bu Xunqi road, and yang-energy must not enter the moon, person caused by malaise, mostly is excess syndrome insomnia.If asthenia with age, deficiency of both QI and blood after insufficiency of vital energy and blood or prolonged illness, imbalance of YIN and YANG or excessive thinking, impairment caused by overstrain heart spleen, cause that to make the heart become homeless foster, body without live or blood deficiency timid, the liver failing to be nourished, god without lead or blood deficiency timid, the liver failing to be nourished or disarmony between the heart and kidney, person caused by asthenic fire rising, the insomnia of meaning deficiency syndrome.In a word, function is disorderly, and pathogen blocks, negative and positive of qi and blood dysequilibrium, and mind is not rather the basic pathogenesis that insomnia occurs.Insomnia, Chinese medicine claims " being insomnia ", and it has dividing of deficiency and excess.Deficiency syndrome as seen dreaming often and waking easily, palpitation and amnesia, Mental fatigue poor appetite, lustreless complexion (insufficiency of blood color), thready and weak pulse, belong to deficiency of both the heart and spleen; If dysphoria and insomnia, dry pharynx dryness of the tongue, or see emission, red tongue, thready and rapid pulse person, belong to hyperactivity of fire caused by deficiency of YIN; See malaise if double, cardiopalmus shies cautious, easily wake up with a start after sleep, stringy and thready pulse person, belong to liver and gall discord; Lack of appetite is uncomfortable in chest as seen for excess syndrome, distension and fullness in the abdomen, stool are smooth, greasy fur, rolling pulse person, belong to the intestines and stomach discord.Sleep can regard the process that wane and wax of yin and yang balances as.
At present, the medicine of Cure for insomnia is a lot, publication number CN 103479961 A(application number 201210195810.8) the Chinese medicine that patent document discloses a kind of Cure for insomnia, it is made up of the raw material of following weight grams: Poria cum Radix Pini 10-14 gram, Rhizoma Coptidis 10-14 gram, Radix Bupleuri 13-17 gram, Caulis Bambusae In Taenia 13-17 gram, Radix Curcumae 13-17 gram, Rhizoma Cyperi 13-17 gram, Pericarpium Citri Reticulatae 10-14 gram, Rhizoma Anemones Altaicae 13-17 gram, Rhizoma Pinelliae 10-14 gram, Arisaema Cum Bile 10-14 gram, Concretio Silicea Bambusae 10-14 gram, Radix Polygalae 12-16 gram.Publication number CN 103961574 A(application number 201410185854.1) the medicine that patent document discloses a kind of Cure for insomnia, form by the weight of following raw material: Sorghum vulgare Pers. 20g, each 35g of dried lily, Rhizoma Pinelliae Preparatum 15g, Poria 20g, Semen Tritici aestivi 30g, Radix Glycyrrhizae 25g, Semen Ziziphi Spinosae 25g, Plumula Nelumbinis 30g, Fructus Lycii 15g, lavandula angustifolia 30g, Caulis Polygoni Multiflori 18g, Semen Sesami Nigrum 30g and Arillus Longan 13g.Publication number CN 104338020 A(application number 201310346026.7) the medicine that patent document discloses a kind of Cure for insomnia, be that prepared by raw material: Bulbus Lilii 5-10g by the Chinese medicine of following parts by weight, Fructus Crataegi 5-10g, raw Semen Ziziphi Spinosae 5-10g, Rhizoma Gastrodiae 10-15g, Radix Angelicae Sinensis 15-20g, Flos Albiziae 10-15g, Radix Glycyrrhizae 10-15g, Concha Ostreae 5-10g, Radix Notoginseng 10-15g, Arillus Longan 10-15g.
At present, Cure for insomnia, mainly based on oral sleeping pill, is often taken and can be brought drug resistance, dependency, the adverse consequencess such as memory impairment, and physical function even can be caused to degenerate, and makes health produce untoward reaction.Although some medicines have appearred in traditional Chinese medical science aspect, curative effect is also indefinite.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide a kind of insomniac and clears away heart-fire relieving restlessness preparation, and have foster brain and calm the nerves, fiery intestinal stasis relieving of dispelling, depressed liver-energy dispersing and QI regulating, dredging collateral is invigorated blood circulation, effect of calming soporific.Another object of the present invention is just to provide above-mentioned insomniac and clears away heart-fire the preparation method of relieving restlessness preparation.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Insomniac clears away heart-fire relieving restlessness preparation, takes off the primary raw material stating quality proportioning and is prepared from: Caulis Polygoni Multiflori 10-15 part; Radix Glycyrrhizae 8-13 part; Herba Oenanthes Javanicae 12-16 part; Clematis filamentosa Dunn 13-18 part; Poria 12-16 part; Herba Aeschynonenes Indicae 10-14 part; Herba lysimachiae capillipedis 11-15 part; Bulbus Lilii 18-23 part; Radix Salviae Miltiorrhizae 16-20 part; Fructus Leonuri 14-16 part; Cymbidium ensifolium (L.) Sw. 11-16 part; Herba Sedi Aizoon 12-15 part; Herba Pellioniae repentis 8-17 part; Lip Rhizoma et radix valerianae 12-16 part; Caulis Piperis Kadsurae 9-13 part; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 13-18 part.
Insomniac clears away heart-fire relieving restlessness preparation, and preferred scheme is, takes off the primary raw material stating quality proportioning and is prepared from: Caulis Polygoni Multiflori 11-14 part; Radix Glycyrrhizae 9-12 part; Herba Oenanthes Javanicae 13-15 part; Clematis filamentosa Dunn 14-17 part; Poria 13-15 part; Herba Aeschynonenes Indicae 11-13 part; Herba lysimachiae capillipedis 12-14 part; Bulbus Lilii 19-22 part; Radix Salviae Miltiorrhizae 17-19 part; Fructus Leonuri 14.5-15.5 part; Cymbidium ensifolium (L.) Sw. 12-15 part; Herba Sedi Aizoon 13-14 part; Herba Pellioniae repentis 11-14 part; Lip Rhizoma et radix valerianae 13-15 part; Caulis Piperis Kadsurae 10-12 part; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 14-17 part.
Insomniac clears away heart-fire relieving restlessness preparation, and the scheme be more preferably is, takes off the primary raw material stating quality proportioning and is prepared from
:caulis Polygoni Multiflori 12 parts; 11 parts, Radix Glycyrrhizae; Herba Oenanthes Javanicae 14 parts; Clematis filamentosa Dunn 15 parts; 14 parts, Poria; Herba Aeschynonenes Indicae 12 parts; Herba lysimachiae capillipedis 13 parts; Bulbus Lilii 21 parts; Radix Salviae Miltiorrhizae 18 parts; Fructus Leonuri 15 parts; 13 parts, Cymbidium ensifolium (L.) Sw.; Herba Sedi Aizoon 13.5 parts; Herba Pellioniae repentis 12 parts; Lip Rhizoma et radix valerianae 14 parts; Caulis Piperis Kadsurae 11 parts; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 15 parts.
Present invention also offers the preparation method that the relieving restlessness preparation that above-mentioned insomniac to be cleared away heart-fire makes pharmaceutically acceptable powder, decoction, pill, tablet and granule.
Described insomniac clears away heart-fire the preparation method of relieving restlessness preparation powder, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools, and is ground into fine powder altogether, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, dry, pulverize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);
(5) by step (1)-(4) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.
Instructions of taking: at every turn get 8-10g, is placed in tea bag, soaks, every day 2-3 time, 4 days courses for the treatment of by the warm waters of about 50 DEG C.
Described insomniac clears away heart-fire the preparation method of relieving restlessness preparation decoction, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 30-40 minute, add step (1) gains and step (3) gains, decoct twice, each decoction (preferably decocts 33-37 minute in 30-40 minute at every turn, be more preferably each decoction 35 minutes), merging filtrate, is concentrated into 1/2 of original volume, obtains decoction.
Above-mentioned insomniac clears away heart-fire the preparation method of relieving restlessness preparation decoction, and the consumption of the preferred rice vinegar of step (1) is the 15%-20% of Poria and Fructus Leonuri gross mass, and the consumption being more preferably rice vinegar is 18% of Poria and Fructus Leonuri gross mass.
Instructions of taking: each 50-80ml, with the warm water delivery service of about 35 DEG C, every day 2-3 time, 4 days courses for the treatment of.
Described insomniac clears away heart-fire the preparation method of relieving restlessness preparation pill, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 30-40 minute, add step (1) gains and step (3) gains, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), merging filtrate, being condensed into relative density is 1.10-1.30(40 DEG C) thick paste, make pill (preferably make the pill that diameter is 3mm-5mm, be more preferably and make the pill that diameter is 4mm).
Instructions of taking: each 10-15 ball, every day 3 times, 4 days courses for the treatment of.
Described insomniac clears away heart-fire the preparation method of relieving restlessness formulation tablet, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 30-40 minute, add step (1) gains and step (3) gains, decoct twice, each decoction (preferably decocts 33-37 minute in 30-40 minute at every turn, be more preferably each decoction 35 minutes), merging filtrate, being condensed into relative density is 1.10-1.30(40 DEG C) thick paste, make tablet.
Instructions of taking: each 2-3 sheet, every day 3 times, 4 days courses for the treatment of.
Described insomniac clears away heart-fire the preparation method of relieving restlessness preparation granules agent, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) by Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 30-40 minute, add step (1) gains and step (3) gains, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), merging filtrate, being concentrated into relative density is 1.10.-1.20(40 DEG C) thick paste, add simple syrup, mixing, make uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
Above-mentioned insomniac clears away heart-fire the preparation method of relieving restlessness preparation granules agent, and the consumption of the preferred simple syrup of step (4) is the 5%-7% of thick paste quality, and the consumption being more preferably simple syrup is 6% of thick paste quality.
Instructions of taking: each 1 bag, every day 3 times, 4 days courses for the treatment of.
Technical advantage of the present invention is mainly reflected in:
1, each raw material effect of the present invention is worked in coordination with, and all medicine compatibilities, have foster brain and calm the nerves, fiery intestinal stasis relieving of dispelling, depressed liver-energy dispersing and QI regulating, and dredging collateral is invigorated blood circulation, effect of calming soporific, has obvious curative effect to insomnia.
2, the present invention can effectively correct function of brain cell disorder, strengthens the modulation function of nervus centralis, makes corticocerebral excitement and suppression be in poised state, thus the symptom of successive elimination insomnia, depression, anxiety, mental disorder.
3, selected materials great majority of the present invention are Chinese medicine material, and not containing any hormone, no dependence, has no side effect and untoward reaction, all harmless to organs such as the heart, liver, kidneys.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1insomniac clears away heart-fire relieving restlessness preparation, takes off the primary raw material stating weight proportion and is prepared from (getting 40g for every part): Caulis Polygoni Multiflori 10 parts; 8 parts, Radix Glycyrrhizae; Herba Oenanthes Javanicae 12 parts; Clematis filamentosa Dunn 13 parts; 12 parts, Poria; Herba Aeschynonenes Indicae 10 parts; Herba lysimachiae capillipedis 11 parts; Bulbus Lilii 18 parts; Radix Salviae Miltiorrhizae 16 parts; Fructus Leonuri 14 parts; 11 parts, Cymbidium ensifolium (L.) Sw.; Herba Sedi Aizoon 12 parts; Herba Pellioniae repentis 8 parts; Lip Rhizoma et radix valerianae 12 parts; Caulis Piperis Kadsurae 9 parts; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 13 parts.
Above-mentioned insomniac clears away heart-fire the preparation method of relieving restlessness preparation powder, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 35 minutes, put in parch container, slow fire heats, and fried dry, cools, and is ground into fine powder altogether, crosses 140 mesh sieves;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 25 minutes, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 35 minutes, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, dry, and porphyrize, crosses 140 mesh sieves;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, dry, pulverize, cross 140 mesh sieves;
(5) by step (1)-(4) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.
Instructions of taking: at every turn get 10g, is placed in tea bag, soaks, every day 3 times, 4 days courses for the treatment of by the warm waters of about 50 DEG C.
embodiment 2insomniac clears away heart-fire relieving restlessness preparation, takes off the primary raw material stating weight proportion and is prepared from (every part of 20g): Caulis Polygoni Multiflori 15 parts; 13 parts, Radix Glycyrrhizae; Herba Oenanthes Javanicae 16 parts; Clematis filamentosa Dunn 18 parts; 16 parts, Poria; Herba Aeschynonenes Indicae 14 parts; Herba lysimachiae capillipedis 15 parts; Bulbus Lilii 23 parts; Radix Salviae Miltiorrhizae 20 parts; Fructus Leonuri 16 parts; 16 parts, Cymbidium ensifolium (L.) Sw.; Herba Sedi Aizoon 15 parts; Herba Pellioniae repentis 17 parts; Lip Rhizoma et radix valerianae 16 parts; Caulis Piperis Kadsurae 13 parts; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 18 parts.
Above-mentioned insomniac clears away heart-fire the preparation method of relieving restlessness preparation decoction, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 35 minutes, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 25 minutes, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 35 minutes, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 35 minutes, add step (1) gains and step (3) gains, decoct twice, each decoction 35 minutes, merging filtrate, be concentrated into 1/2 of original volume, obtain decoction.
Instructions of taking: each 70ml, every day 3 times, 4 days courses for the treatment of.
model case onewhat XX, female, 27 years old, people from Linyi.Mrs He is relatively painstaking from little study, due to the undue concern of father and mother and people around, Mrs He is often had a sleepless night, especially rises up into after senior middle school.Usually there is the symptoms such as insomnia, agitation, tinnitus, lassitude of the limbs and weakness.Worked afterwards, pressure of one's work still pressure Mrs get He is out of breath, and usually occurs difficulty falling asleep, headache, giddy, tinnitus, sleepy unable, stable class sleeping pill can only be relied on every day to fall asleep, and Long-term taking medicine is formed and relies on, strengthen dose gradually, sleeper effect is not but got better.
Taking gained insomniac of the present invention afterwards clears away heart-fire after 2 courses for the treatment of of relieving restlessness preparation decoction (embodiment 2), and can sleep substantially every night five or six hours, symptom obviously alleviates, and daytime, conscious spirit obviously took a turn for the better.Fully recovering after continuing to take 1 course for the treatment of, with preventing so far, having no recurrence.
embodiment 3insomniac clears away heart-fire relieving restlessness preparation, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Caulis Polygoni Multiflori 11 parts; 9 parts, Radix Glycyrrhizae; Herba Oenanthes Javanicae 13 parts; Clematis filamentosa Dunn 14 parts; 13 parts, Poria; Herba Aeschynonenes Indicae 11 parts; Herba lysimachiae capillipedis 12 parts; Bulbus Lilii 19 parts; Radix Salviae Miltiorrhizae 17 parts; Fructus Leonuri 14.5 parts; 12 parts, Cymbidium ensifolium (L.) Sw.; Herba Sedi Aizoon 13 parts; Herba Pellioniae repentis 11 parts; Lip Rhizoma et radix valerianae 13 parts; Caulis Piperis Kadsurae 10 parts; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 14 parts.
Above-mentioned insomniac clears away heart-fire the preparation method of relieving restlessness preparation pill, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 35 minutes, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 25 minutes, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 35 minutes, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 35 minutes, add step (1) gains and step (3) gains, decoct twice, each decoction 35 minutes, merging filtrate, being condensed into relative density is 1.20(40 DEG C) thick paste, make the pill that diameter is 4mm.
Instructions of taking: each 10 balls, every day 3 times, 4 days courses for the treatment of.
embodiment 4insomniac clears away heart-fire relieving restlessness preparation, takes off the primary raw material stating weight proportion and is prepared from (getting 25g for every part): Caulis Polygoni Multiflori 14 parts; 12 parts, Radix Glycyrrhizae; Herba Oenanthes Javanicae 15 parts; Clematis filamentosa Dunn 17 parts; 15 parts, Poria; Herba Aeschynonenes Indicae 13 parts; Herba lysimachiae capillipedis 14 parts; Bulbus Lilii 22 parts; Radix Salviae Miltiorrhizae 19 parts; Fructus Leonuri 15.5 parts; 15 parts, Cymbidium ensifolium (L.) Sw.; Herba Sedi Aizoon 14 parts; Herba Pellioniae repentis 14 parts; Lip Rhizoma et radix valerianae 15 parts; Caulis Piperis Kadsurae 12 parts; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 17 parts.
Above-mentioned insomniac clears away heart-fire the preparation method of relieving restlessness formulation tablet, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 35 minutes, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 25 minutes, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 35 minutes, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 35 minutes, add step (1) gains and step (3) gains, decoct twice, each decoction 35 minutes, merging filtrate, being condensed into relative density is 1.20(40 DEG C) thick paste, make tablet.
Instructions of taking: each 2-3 sheet, every day 3 times, 4 days courses for the treatment of.
model case twoxu XX, female, 19 years old, people from From Shijiazhuang City of Hebei Province.Mrs Xu is a student of high two, and learning pressure is large especially, and it is also high especially to add the hope that father and mother express her, and oneself belongs to that personality is eager to excel very much, so Mrs Xu feels the stress especially large.Start to occur insomnia in high two second half year, toss and turn at night, in brain, always appear some things topsy-turvy in one's mind.Just started to be insomnia in evening, starting after several days to occur to attend class daytime, spirit is not enough, absent minded, emotion is impatient, school grade decline.Start not take notice of especially, find that temper becomes irascible especially afterwards, be weary of study, also do not like speaking with classmate, to school work and future despair.
Taking gained insomniac of the present invention clears away heart-fire after 2 courses for the treatment of of relieving restlessness formulation tablet (embodiment 4), and symptom obviously alleviates, and insomnia number of times obviously reduces, and sleep quality improves a lot, also spiritedness of attending class daytime, more can focus one's attention on and have learned.After continuing to take 2 courses for the treatment of, insomnia disappears, and do not worry to have can't fall asleep before sleep in the evening yet, and the mental status is also good especially.Later stage visits and learns always keep fine, and school grade is greatly improved.
embodiment 5insomniac clears away heart-fire relieving restlessness preparation, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Caulis Polygoni Multiflori 12 parts; 11 parts, Radix Glycyrrhizae; Herba Oenanthes Javanicae 14 parts; Clematis filamentosa Dunn 15 parts; 14 parts, Poria; Herba Aeschynonenes Indicae 12 parts; Herba lysimachiae capillipedis 13 parts; Bulbus Lilii 21 parts; Radix Salviae Miltiorrhizae 18 parts; Fructus Leonuri 15 parts; 13 parts, Cymbidium ensifolium (L.) Sw.; Herba Sedi Aizoon 13.5 parts; Herba Pellioniae repentis 12 parts; Lip Rhizoma et radix valerianae 14 parts; Caulis Piperis Kadsurae 11 parts; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 15 parts.
Above-mentioned insomniac clears away heart-fire the preparation method of relieving restlessness preparation granules agent, and step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 35 minutes, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 25 minutes, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 35 minutes, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 35 minutes, add step (1) gains and step (3) gains, decoct twice, each decoction 35 minutes, merging filtrate, being concentrated into relative density is 1.15(40 DEG C) thick paste, add simple syrup, mixing, makes uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
Instructions of taking: each 1 bag, every day 3 times, 4 days courses for the treatment of.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Caulis Polygoni Multiflori: sweet in the mouth, property is put down.GUIXIN, Liver Channel.For the dry rattan of polygonum multiflorum thunb.There is nourishing blood to tranquillize the mind, effect of dispelling wind and removing obstruction in the collateral.For insomnia and dreamful sleep. blood deficiency general pain, rheumatic arthralgia; External treatment skin pruritus.
Radix Glycyrrhizae: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.For the dry root and rhizome of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, effect of relieving spasm to stop pain.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of institute's abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity.
Herba Oenanthes Javanicae: sweet in the mouth, pungent, cool in nature.Attach to the lung and stomach meridians.For the stem and leaf of samphire Herba Apii graveolentis.Contained energy 54kj in every 100g, protein 1.4g, fatty 0.2g, dietary fiber 0.9g, carbohydrate 1. 3g, carotene 380 μ g, retinol equivalent 63 μ g, thiamine 0.01mg, riboflavin 0.19mg, nicotinic acid 1mg, vitamin C 5mg, vitamin E 0.32mg, potassium 212mg, sodium 40.9mg, calcium 38mg, magnesium 16mg, ferrum 6.9mg, manganese 0.79mg, zinc 0.38mg, copper 0.1mg, phosphorus 38mg, selenium 0.81 μ g.There is clearing away heat-damp and promoting diuresis, effect of suppressing the hyperactive liver stomach invigorating.For hypertension, dizziness, sudden high fever excessive thirst, jaundice, edema, urine heat puckery unfavorable, menoxenia, leucorrhea with red and white discharge, scrofula, mumps.
Clematis filamentosa Dunn: bitter in the mouth, cool in nature.GUIXIN, Liver Channel.For the leaf of Ranunculaceae Clematis filamentosa Dunn.Containing flavonoid, reducing sugar, polysaccharide, steroidal, phenolic substance, tannin, aminoacid etc.There is clearing away liver-fire, mind calming god, blood pressure lowering, effect of removing obstruction in the collateral to relieve pain.For hypertension, insomnia, headache, numb limbs and tense tendons, wind-heat of liver channel, conjunctival congestion and swelling pain, acute toothache, rheumatic arthralgia.
Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.For the dry sclerotia of On Polyporaceae Poria.Have promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, relieve internal heat anticancer effect.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia, dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, and malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.
Herba Aeschynonenes Indicae: sweet in the mouth, light, cold in nature.Attach to the lung and stomach meridians.For the herb of bean kind of plant Herba Aeschynonenes Indicae.There is clearing away heat-damp and promoting diuresis, dispelling pathogenic wind for improving eyesight, effect of lactogenesis.For pyretic stranguria, stranguria with blood, edema, has loose bowels, furuncle and phyma, skin ulcer scabies, conjunctival congestion and swelling pain, and look unfamiliar nebula, nyctalopia, arthralgia, and puerpera's breast is few.
Herba lysimachiae capillipedis: acrid in the mouth, warm in nature.For the root and rhizome of labiate Herba lysimachiae capillipedis.Containing a small amount of apigenin and luteolin.Having removing dampness keeps away turbid, effect of inducing diuresis to remove edema.Vomit and diarrhoea for summer-heat is aobvious, edema, dysuria.
Bulbus Lilii: sweet in the mouth, cold in nature.GUIXIN, lung meridian.For the dry meat scale leaf of liliaceous plant tiger lily, Bulbus Lilii or Lilium tenuifolium.There is nourishing YIN and moistening the lung, effect of clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold in nature, nontoxic.GUIXIN, Liver Channel.For the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.
Fructus Leonuri: acrid in the mouth, hardship, cold nature.GUIXIN bag, Liver Channel.For the dry mature fruit of labiate Herba Leonuri.There is promoting blood flow to regulate menstruation, effect of liver heat removing and eyesight improving.For menoxenia, amenorrhea, dysmenorrhea, cataract, dizzy distending pain.
Cymbidium ensifolium (L.) Sw.: acrid in the mouth, sweet, property is put down.For the flower of the orchid family epidendrum sword-leaved cymbidium, Herba Cymbidii Goeringii, orchid etc.There is nourishing YIN and moistening the lung, promoting diuresis to eliminate damp pathogen, effect of heat-clearing and toxic substances removing.For uncomfortable in chest, diarrhoea, dry cough chronic cough, hemoptysis, optic atrophy.
Herba Sedi Aizoon: sweet in the mouth, property are flat.Return liver, kidney two warp.For the herb of crassulaceae plants Herba Sedi Aizoon.Containing alkaloid, oleanolic acid, sitosterol, sedoheptose, sucrose, fructose, protein, flavonoid and organic acid.There is detumescence, analgesic therapy, hemostasis, effect of blood stasis dispelling.For spitting blood, epistaxis, has blood in stool, hematuria, metrorrhagia, acute mastitis, traumatic injury.
Herba Pellioniae repentis: sweet in the mouth, micro-puckery, cool in nature.Return liver, the heart, spleen channel.For the herb of contrayerva Herba Pellioniae repentis.There is clearing away heat-damp and promoting diuresis, effect of mind tranquilizing and the heart calming.For damp and hot yellow cellulitis, ascites, insomnia, forgetful, allergic dermatitis, ulcer of the lower limb, furuncle toxic swelling.
Lip Rhizoma et radix valerianae: acrid in the mouth, cool in nature.For the Herb of labiate lip Rhizoma et radix valerianae.Containing flavone: gloomy rhinoceros grass element, obscure flower glycoside, 7-methyl 5,7,4'-trihydroxy-6,8,3'-trimethoxyflavone, chrysin-7-O-rutinoside and caffeic acid, 4-hydroxyl-3,5-dimethoxy p-methyl, oleanolic acid, daflon.There is mind tranquilizing and the heart calming, effect of diuretic heat clearing away.For cardiopalmus, insomnia, edema, cold, fever, conjunctival congestion and swelling pain, sore swollen toxin.
Caulis Piperis Kadsurae: acrid in the mouth, slightly warm in nature.For root and the old rattan of Magnoliaceae Kadsura abnormity Fructus Schisandrae Sphenantherae.There is expelling wind and removing dampness, regulating QI to relieve pain, effect of promoting blood circulation to remove blood stasis.For rheumatism bones and muscles pain, lumbar muscle strain, sciatica, acute gastroenteritis, chronic gastritis, taste-blindness rate, dysmenorrhea, puerperal abdonimal pain, traumatic injury.
Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root: sweet in the mouth, property is put down.Return stomach, heart channel.For root or the root bark of Hamamelidaceae Plants China Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．).Containing Bergeninum, quercitrin.There is dispelling wind stomach function regulating, effect of mind tranquilizing and the heart calming.For diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, headache, nausea and vomiting, cardiopalmus, dysphoria.
test examplein order to verify that gained insomniac of the present invention clears away heart-fire the curative effect of relieving restlessness preparation (embodiment 5), has done contrast test in JIUYUE, 2008 in July ,-2010:
General data: the patient of screening 200 example insomnia, wherein minimal ages 17 years old, max age 65 years old, 37.9 years old mean age; 17-30 year 49 people, 31-40 year 47 people, 41-50 year 53 people, 51-65 year 51 people.Be divided into experimental group and matched group two groups (wherein experimental group 150 people, matched group 50 people) at random, two groups are compared there was no significant difference (P > 0.05), have comparability in sex, age, the course of disease, state of an illness scoring etc.
Diagnostic criteria: 1. main suit or difficulty falling asleep, or be difficult to maintain sleep, or poor sleeping quality.2. this sleep disordered at least generation weekly also continues more than 1 month 3 times.3. day and night insomnia is absorbed in, the consequence of excessive worry insomnia.4. amount of sleep and/or the dissatisfied of matter cause obvious worries or have impact on society and occupational function.
Usage and dosage: experimental group is taken gained insomniac of the present invention and to be cleared away heart-fire the agent of relieving restlessness preparation granules, each 1 bag, every day 3 times, 4 days courses for the treatment of; Matched group takes other medicine (as Yang Yin Zhen Jing Tablet, beneficial peace pill etc.), wherein, and Yang Yin Zhen Jing Tablet: oral, a 4-6 sheet, 3 times on the one.Benefit peace pill: oral, every day 1 to 2 time, each 12 to 18 balls.
Criterion of therapeutical effect: recovery from illness: sleep is normal, more than the 6 hours length of one's sleep, simultaneous phenomenon disappears.Effective: total sleep time extends more than 2 hours, but less than 6 hours, simultaneous phenomenon improved.Invalid: before sleeping as taking medicine, or extend the length of one's sleep less than 2 hours, symptom is without improvement.
4 courses for the treatment of of medication treatment, observe latter 6 months for the treatment of.Take the matched group of other drug and take gained insomniac of the present invention and to clear away heart-fire the Comparison of therapeutic of experimental group of relieving restlessness preparation, result is as shown in table 1:
Table 1
As can be seen from Table 1, take gained insomniac of the present invention and clear away heart-fire the cure rate of relieving restlessness preparation up to 76.67%, effective percentage is up to 97.33%; And the cure rate taking other drug only 42%, effective percentage also only has 78%, and inefficiency is up to 22%.So gained insomniac of the present invention clears away heart-fire, the successful of relieving restlessness preparation is better than the effect of other drug.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or obtain undoubtedly according to the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. insomniac clears away heart-fire relieving restlessness preparation, it is characterized in that, takes off the primary raw material stating quality proportioning and be prepared from: Caulis Polygoni Multiflori 10-15 part; Radix Glycyrrhizae 8-13 part; Herba Oenanthes Javanicae 12-16 part; Clematis filamentosa Dunn 13-18 part; Poria 12-16 part; Herba Aeschynonenes Indicae 10-14 part; Herba lysimachiae capillipedis 11-15 part; Bulbus Lilii 18-23 part; Radix Salviae Miltiorrhizae 16-20 part; Fructus Leonuri 14-16 part; Cymbidium ensifolium (L.) Sw. 11-16 part; Herba Sedi Aizoon 12-15 part; Herba Pellioniae repentis 8-17 part; Lip Rhizoma et radix valerianae 12-16 part; Caulis Piperis Kadsurae 9-13 part; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 13-18 part.
2. insomniac according to claim 1 clears away heart-fire relieving restlessness preparation, it is characterized in that, takes off the primary raw material stating quality proportioning and be prepared from: Caulis Polygoni Multiflori 11-14 part; Radix Glycyrrhizae 9-12 part; Herba Oenanthes Javanicae 13-15 part; Clematis filamentosa Dunn 14-17 part; Poria 13-15 part; Herba Aeschynonenes Indicae 11-13 part; Herba lysimachiae capillipedis 12-14 part; Bulbus Lilii 19-22 part; Radix Salviae Miltiorrhizae 17-19 part; Fructus Leonuri 14.5-15.5 part; Cymbidium ensifolium (L.) Sw. 12-15 part; Herba Sedi Aizoon 13-14 part; Herba Pellioniae repentis 11-14 part; Lip Rhizoma et radix valerianae 13-15 part; Caulis Piperis Kadsurae 10-12 part; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 14-17 part.
3. insomniac according to claim 1 clears away heart-fire relieving restlessness preparation, it is characterized in that, takes off the primary raw material stating quality proportioning and be prepared from: Caulis Polygoni Multiflori 12 parts; 11 parts, Radix Glycyrrhizae; Herba Oenanthes Javanicae 14 parts; Clematis filamentosa Dunn 15 parts; 14 parts, Poria; Herba Aeschynonenes Indicae 12 parts; Herba lysimachiae capillipedis 13 parts; Bulbus Lilii 21 parts; Radix Salviae Miltiorrhizae 18 parts; Fructus Leonuri 15 parts; 13 parts, Cymbidium ensifolium (L.) Sw.; Herba Sedi Aizoon 13.5 parts; Herba Pellioniae repentis 12 parts; Lip Rhizoma et radix valerianae 14 parts; Caulis Piperis Kadsurae 11 parts; Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 15 parts.
4. to clear away heart-fire relieving restlessness preparation according to the arbitrary described insomniac of claim 1-3, it is characterized in that, the preparation method of described powder, step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools, and is ground into fine powder altogether, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, dry, pulverize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);
(5) by step (1)-(4) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.
5. to clear away heart-fire relieving restlessness preparation according to the arbitrary described insomniac of claim 1-3, it is characterized in that, the preparation method of described decoction, step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 30-40 minute, add step (1) gains and step (3) gains, decoct twice, each decoction (preferably decocts 33-37 minute in 30-40 minute at every turn, be more preferably each decoction 35 minutes), merging filtrate, is concentrated into 1/2 of original volume, obtains decoction.
6. insomniac according to claim 5 clears away heart-fire the preparation method of relieving restlessness preparation decoction, it is characterized in that: the consumption of the preferred rice vinegar of step (1) is the 15%-20% of Poria and Fructus Leonuri gross mass, and the consumption being more preferably rice vinegar is 18% of Poria and Fructus Leonuri gross mass.
7. to clear away heart-fire relieving restlessness preparation according to the arbitrary described insomniac of claim 1-3, it is characterized in that, the preparation method of described pill, step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 30-40 minute, add step (1) gains and step (3) gains, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), merging filtrate, being condensed into relative density is 1.10-1.30(40 DEG C) thick paste, make pill (preferably make the pill that diameter is 3mm-5mm, be more preferably and make the pill that diameter is 4mm).
8. to clear away heart-fire relieving restlessness preparation according to the arbitrary described insomniac of claim 1-3, it is characterized in that, the preparation method of described tablet, step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 30-40 minute, add step (1) gains and step (3) gains, decoct twice, each decoction (preferably decocts 33-37 minute in 30-40 minute at every turn, be more preferably each decoction 35 minutes), merging filtrate, being condensed into relative density is 1.10-1.30(40 DEG C) thick paste, make tablet.
9. to clear away heart-fire relieving restlessness preparation according to the arbitrary described insomniac of claim 1-3, it is characterized in that, the preparation method of described granule, step is as follows:
(1) be placed in container by Poria and Fructus Leonuri, add rice vinegar and mix thoroughly, moistening 30-40 minute, put in parch container, slow fire heats, and fried dry, cools;
(2) smashed to pieces by Radix Glycyrrhizae, decoct with water 2 times, each decoction 20-30 minute, filters, merging filtrate;
(3) Herba lysimachiae capillipedis, Radix Salviae Miltiorrhizae, Caulis Piperis Kadsurae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are cut into slices, be placed in marmite, add step (2) gained filtrate, soak 30-40 minute, slow fire is heated to cease fire when liquorice liquid is boiled dry substantially, takes out, cools;
(4) by Caulis Polygoni Multiflori, Herba Oenanthes Javanicae, Clematis filamentosa Dunn, Herba Aeschynonenes Indicae, Bulbus Lilii, Cymbidium ensifolium (L.) Sw., Herba Sedi Aizoon, Herba Pellioniae repentis and lip Rhizoma et radix valerianae are cleaned, be placed in marmite, soak 30-40 minute, add step (1) gains and step (3) gains, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), merging filtrate, being concentrated into relative density is 1.10.-1.20(40 DEG C) thick paste, add simple syrup, mixing, make uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
10. insomniac according to claim 9 clears away heart-fire the preparation method of relieving restlessness preparation granules agent, it is characterized in that: the consumption of the preferred simple syrup of step (4) is the 5%-7% of thick paste quality, and the consumption being more preferably simple syrup is 6% of thick paste quality.
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| CN201510153272.XA CN104721569A (en) | 2015-04-02 | 2015-04-02 | Preparation for clearing away heart fire and relieving restlessness of insomniacs and preparation method of preparation |
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|---|---|---|---|---|
| CN1701683A (en) * | 2005-06-14 | 2005-11-30 | 王浩贵 | Health caring noodles with wild or spiny jujuba seeds |
| CN101032560A (en) * | 2006-07-15 | 2007-09-12 | 广西玉林制药有限责任公司 | Chinese medicine composition for treating somnipathy and preparing method thereof |
| KR101242596B1 (en) * | 2010-11-30 | 2013-03-19 | 건국대학교 산학협력단 | Composition comprising an extact of cordyceps militaris and cordycepin isolated thereform for the improvement and remedial of insomnia |
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|---|---|---|---|---|
| CN1701683A (en) * | 2005-06-14 | 2005-11-30 | 王浩贵 | Health caring noodles with wild or spiny jujuba seeds |
| CN101032560A (en) * | 2006-07-15 | 2007-09-12 | 广西玉林制药有限责任公司 | Chinese medicine composition for treating somnipathy and preparing method thereof |
| KR101242596B1 (en) * | 2010-11-30 | 2013-03-19 | 건국대학교 산학협력단 | Composition comprising an extact of cordyceps militaris and cordycepin isolated thereform for the improvement and remedial of insomnia |
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| 宋任婴: "自拟安眠汤治疗顽固性失眠52例临床观察", 《中医药导报》 * |
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