CN104721475B - A kind of health care product used for relieving physical fatigue and preparation method thereof - Google Patents
A kind of health care product used for relieving physical fatigue and preparation method thereof Download PDFInfo
- Publication number
- CN104721475B CN104721475B CN201510182615.5A CN201510182615A CN104721475B CN 104721475 B CN104721475 B CN 104721475B CN 201510182615 A CN201510182615 A CN 201510182615A CN 104721475 B CN104721475 B CN 104721475B
- Authority
- CN
- China
- Prior art keywords
- parts
- chrysanthemum
- chinese
- medicinal extract
- fruit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention discloses a kind of health care product used for relieving physical fatigue and preparation method thereof, by carrying out alcohol extracting to the fruit of Chinese wolfberry, chrysanthemum, rhodiola root and matrimony vine residue progress water are carried again, concentrate drying gets dry extract, it is crushed after mixing with Chinese yam again, obtain mixed powder, the health products of the canned physical fatigue that is eased at capsule.Compared with prior art, the preparation of the present invention is prepared using traditional Chinese medicine, especially formula is simple, composition is reasonable, its product has tonifying spleen nourishing the stomach, engender liquid and benefic lung, antifatigue effect effective percentage is played close to 100%, gained preparation, which is prepared, especially by the method for the present invention is very beneficial for absorption of human body, it is found by mouse experiment, in the case of the sheet lead for 5% weight of bearing a heavy burden, swimming power exhausts the time and is considerably longer than blank control group, and the difference of high dose and middle dose group and blank control group equal highly significant experiment mice.It is obtained by blood lactase acid measurement, the present invention can play antifatigue effect by accelerating the elimination of blood lactase acid.
Description
Technical field
The present invention relates to the health-care preparation of the field of Chinese medicines more particularly to a kind of health products for being exclusively used in alleviating physical fatigue
And preparation method thereof.
Background technology
Physical fatigue refer to it is lasting or overworked after caused by uncomfortable and working efficiency the phenomenon that declining, be modern
An outstanding problem present in society.With the development of society, the raising of life prime number, people's rhythm of life is accelerated increasingly,
Work, study intensity are increasingly reinforced；And high protein, high fat diet chance increase, amount of exercise is fewer and fewer.Cause to be chronically at
Fatigue state crowd's ratio increases, so that seriously affecting people's health, society and expanding economy.The energy of people is limited,
Life, the working and learning of this fast pace and high intensity can often make one to feel fatigue, and be chronically at sub-health state, seriously
Influence work, learning efficiency and quality of life.Chinese medicine thinks " long internal lesion caused by overexertion gas ", and excessively lasting fatigue can lead to gas
Void shows as easily tired, mood is irritated, decrease of memory, thought slowness, fatigue resistance decline etc., will appear in the course of time
It has a delicate constitution, the deficient disease such as resistance declines, but does not reach pathogenic degree also.Nowadays, more and more people want through various sides
Formula relieves fatigue symptom to reach, and wherein rational diet, antifatigue drug and food have become a kind of society need, using Chinese medicine at
The health products made are divided not have any injury for human body, the constituent also forbidden without any country, therefore, antifatigue
The research of product and functional health-care food is of great significance and wide social foreground.
The health products of present market sale relieved fatigue some can achieve the effect that really it is certain relieve fatigue, but
Be the monarch due to formulation selection, minister, help composition cost it is higher, selling price is also higher, and ordinary people can not consume, unfavorable
In marketing.As Chinese patent CN200910152234.7 discloses a kind of health food for relieving fatigue preparation and its preparation
Method selects American Ginseng for assistant, expensive, so selecting low cost, efficient traditional Chinese medicine health care product is art technology
Personnel wish the technical issues of solving and never solving.
Invention content
In view of this, a kind of health care product used for relieving physical fatigue of present invention offer and preparation method thereof, in low cost
Under conditions of synthesize the ideal health products for alleviating physical fatigue.
Health care product used for relieving physical fatigue of the present invention, constituent include：Rhodiola root, the fruit of Chinese wolfberry, chrysanthemum
And Chinese yam.
Rhodiola Rosea L of Xinjiang system Crassulaceae Rhodida plant is traditional Chinese medicine, and root and rhizome are medicinal, and pharmacological action is ground
Study carefully and shows that rhodiola root has the pharmacological actions such as antitumor, anti-oxidant, antifatigue, radioresistance, delaying senility.Especially it is anti-tired
Work with more apparent, some researches show that：Rhodiola root can be such that the fatigue for largely moving formation is improved, and dominant mechanism is to make
Body more saves ground and utilizes glycogen and atriphos, and more fully energy (Chen Yadong etc., 2002) is provided for muscle activity.It is right
Diaphragmatic fatigue and diaphragmatic muscle damage have protective effect, are the preferable auxiliary of one kind of endurance exercise and the movement of resistance to speed
Drug can also be used as health treatment and improve Healthy People aerobic capacity and anti-fatigue ability.
The fruit of Chinese wolfberry is matrimony vine of solanaceae plant dry mature fruit, and matrimony vine is Xinjiang superior resources, is that the tradition in China is rare
Chinese medicine is the medical and edible dual purpose plant for enjoying great prestige China and foreign countries.Matrimony vine is also the good merchantable brand of medicine-food two-purpose, and the fruit of Chinese wolfberry has excited brain and property
The effect of nerve reduces the danger that the carry-on somatic tissue of the elderly degenerates and suffer from senile macular degeneration；And there is protection
The effect of liver can inhibit fat in intrahepatic deposition and promote liver cell newborn.Meanwhile also there is antifatigue, immunological regulation, resist
The various biologicals such as tumour, anti-aging act on, and especially antifatigue effect is one of more apparent effect of polysaccharides.Li Guoli etc. with
Oxidative Ability of Sport Training Mouse is animal model, has investigated influence of the polysaccharides to Endurance and internal activities of antioxidant enzymes.As a result
Show that LBP can be obviously prolonged mouse and exhaust swimming time, improves the endurance of exercised rats, while mouse blood can be significantly improved
The activity of slurry, muscular tissue, hepatic tissue SOD and GSH-Px, to be conducive to the removing of active oxygen, delayed motion fatigue and movement
The generation of damage.Luo Qiong etc. is fed purified lycium barbarum polysaccharide (LBP-X) by 5,10,20,50 and 100mg/ (kgd) small respectively
Mouse, carries out anti-fatigue test, which finds that polysaccharides has apparent antifatigue effect.Peng Xiaodong uses river pulse-type current
The directly stimulation in vitro gastrocnemius of toad is as Tiredness model, the results showed that, 6.4~25.6mg/ml polysaccharides can be such that muscle receives
The contracting duration declines：Sarcolactic acid fowl amount declines；On contraction of muscle amplitude without influence.
Chrysanthemum is feverfew chrysanthemum dry capitulum.Chrysanthemum is sweet, bitter, is slightly cold；Return lung, Liver Channel；With relieve heat heat-clearing,
Flat liver improving eyesight, heat-clearing toxin-expelling functions.Chinese yam is the dry rhizome of Dioscoreaceae plant, and with tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying is puckery
Effect of essence.
Preferably, the weight quota of health care product used for relieving physical fatigue constituent is：10-60 parts of rhodiola root, Chinese holly
5-30 parts of 10-35 parts of matrimony vine, 10-35 parts of chrysanthemum and Chinese yam.
Above-mentioned preferred weight is：45-55 parts of rhodiola root, 25-35 parts of the fruit of Chinese wolfberry, 20-30 parts of chrysanthemum and Chinese yam
8-12 parts, most preferably：10 parts of 50 parts of rhodiola root, 30 parts of the fruit of Chinese wolfberry, 25 parts of chrysanthemum and Chinese yam.
The preparation method of above-mentioned health care product used for relieving physical fatigue, in turn includes the following steps：
A, the fruit of Chinese wolfberry is carried 1~2 time with 50%~70% ethyl alcohol, 5~10 times of amounts, and each reflux extracting time 1~3 hour carries
It takes liquid to concentrate, obtains medicinal extract, residue is spare.
B, residue mixes in chrysanthemum, rhodiola root and above-mentioned steps A, with 5~10 times of amount water refluxing extractions 2~3 times, every time 1
~3 hours, merges extracting solution, be concentrated to give medicinal extract；Slag recovering in step A is utilized, cost of manufacture is reduced.
C, the medicinal extract for producing above-mentioned steps A and B merges, and is dried to dry cream at 50 DEG C~70 DEG C, is uniformly mixed with Chinese yam
After crush, obtain mixed powder, it is canned at capsule, you can.
Extracting solution thickening temperature described in step step A is consistent with the extracting solution thickening temperature described in step B；It is preferred that temperature
Ranging from 50 DEG C~70 DEG C of degree, the concentration preferably carries out under negative pressure, and the negative pressure is generally in 0.04MPa or less.
The medicinal extract relative density that the medicinal extract that step A is produced is produced with step B is consistent；It is preferred that relative density is 1.30
~1.35.
The dry cream moisture that step C is dried to is preferably lower than 9%, the mixed powder after crushing, and most well 80~120 mesh sieve is protected
The particle for holding mixed powder is uniform, convenient follow-up canned.
Compared with prior art, preparation of the invention is prepared using traditional Chinese medicine, and especially formula is simple, and composition closes
There is tonifying spleen nourishing the stomach, engender liquid and benefic lung to play antifatigue effect effective percentage close to 100%, especially by the present invention for reason, product
Method prepare gained preparation and be very beneficial for absorption of human body, found by mouse experiment, experiment mice is in 5% weight of bearing a heavy burden
In the case of sheet lead, swimming power exhausts the time and is considerably longer than blank control group, and high dose and middle dose group and blank control group
The equal highly significant of difference.It is obtained by blood lactase acid measurement, the present invention can be played anti-tired by accelerating the elimination of blood lactase acid
The effect of labor.
Description of the drawings
Influence diagram of Fig. 1 Qis chrysanthemum capsule to the mice burden swimming time；
Influence diagram of Fig. 2 Qis chrysanthemum capsule to mice serum urea nitrogen content；
Influence diagram of Fig. 3 Qis chrysanthemum capsule to mouse Serum lactic acid content.
Specific implementation mode
In order to make those skilled in the art more fully understand technical scheme of the present invention, with reference to specific embodiment pair
The present invention is described in further detail.
The following examples are only intended to illustrate the technical solution of the present invention more clearly, and cannot limit the present invention with this
Protection domain.
Embodiment 1：Its Chinese medicine composition weight quota be：15 parts of rhodiola root, 10 parts of the fruit of Chinese wolfberry, 10 parts of chrysanthemum and Chinese yam
5 parts.
A, the fruit of Chinese wolfberry is carried 1 time with 50% ethyl alcohol, 5 times of amounts, each reflux extracting time 1 hour, and 50 DEG C of extracting solution concentrations obtain
Medicinal extract, until relative density 1.30, residue is spare.
B, residue mixes in chrysanthemum, rhodiola root and above-mentioned steps A, measures water refluxing extraction 2 times with 5 times, 1 hour every time, closes
And extracting solution, 50 DEG C are concentrated to give medicinal extract, until relative density 1.30.
C, the medicinal extract for producing above-mentioned steps A and B merges, and dry cream is dried at 50 DEG C or so, and moisture is less than 9%,
It is crushed after mixing with Chinese yam, obtains mixed powder, cross 80 mesh sieve, it is canned at capsule, you can.
Embodiment 2：Its Chinese medicine composition weight quota be：50 parts of rhodiola root, 30 parts of the fruit of Chinese wolfberry, 25 parts of chrysanthemum and Chinese yam
10 parts.
A, the fruit of Chinese wolfberry is carried 2 times with 60% ethyl alcohol, 8 times of amounts, each reflux extracting time 2 hours, and 60 DEG C of extracting solution concentrations obtain
Medicinal extract, until relative density 1.33, residue is spare.
B, residue mixes in chrysanthemum, rhodiola root and above-mentioned steps A, measures water refluxing extraction 2 times with 8 times, 2 hours every time, closes
And extracting solution, 60 DEG C are concentrated to give medicinal extract, until relative density 1.33.
C, the medicinal extract for producing above-mentioned steps A and B merges, and dry cream is dried at 60 DEG C or so, and moisture is less than 4%,
It is crushed after mixing with Chinese yam, obtains mixed powder, sieve with 100 mesh sieve, it is canned at capsule, you can.
With reference to experiment, the health care product used for relieving physical fatigue produced to the present embodiment (i.e. Qi chrysanthemum capsule) is beneficial
Effect illustrates.
2.1 experimental method
(1) 88 mouse of animal feeding are randomly divided into two batches, every batch of 44 after SPF animal houses adaptable fed 2 days.
Every batch of divides blank control group, Qi chrysanthemum capsule high dose group, middle dose group and low dose group, every group 11.Each dosage of Qi chrysanthemum capsule
The drug (ig.0.2ml/10g) of group gavage various concentration is normal to organize gavage equivalent pure water, once a day, continuous 30 days.First
It criticizes mouse and exhausts experiment for power of swimming, second batch is detected for serum urea nitrogen and blood lactase acid detection is tested.
(2) overview observes each group mouse situation daily, weighs mouse weight weekly.
(3) after swimming power exhausts experiment last gavage 30min, in mouse tail proximal part 1/3-2/3 intersections, with by pre-
The galvanized wire for testing 5% determining weight weight bears a heavy burden.By mouse be placed in depth of water 30cm, 25.0 ± 1.0 DEG C of water temperature water tank in, note
Record mouse is to sink under the water time that 10s cannot be floated on the surface of the water of head being the mice burden swimming time swimming.
(4) after serum urea nitrogen detection last gavage 30min, the not swimming with a load attached to the body 90min in 30 DEG C of water, rest
60min posterior orbits blood sampling 0.1ml or so.4 DEG C of standing 3h, low temperature 3500 leave heart 15min, take serum 20ul, detects.
(5) take a blood sample 0.05ml after blood lactase acid detection last gavage 30min；It bears a heavy burden in 30 DEG C of water 3% weight weight
Take a blood sample 0.05ml immediately after galvanized wire swimming 6min；Take a blood sample 0.05ml again after rest 20min.It is prepared by supernatant：Take sample to be tested
Protein precipitant 0.3ml mixings are added in 0.05ml, and 3500 leave heart 10min, and supernatant is taken to be measured.
(6) all data of statistical method are shown with X ± S, and comparison among groups are examined using t, p value<0.05 is significant difference, there is system
Meter learns meaning.
2.2 experimental result
(1) influence of the Qi chrysanthemum capsule to mouse weight
The action of each group mouse, appearance are without exception in experimentation.Compared with blank control group, each dosage group of Qi chrysanthemum capsule
The weight of mouse is just decreased obviously after being administered 1 week, difference significance, shows that Qi chrysanthemum capsule has one to mouse weight growth
Fixing is rung.It the results are shown in Table 1 and table 2
Influence of the 1 Qi chrysanthemum capsule of table to first mouse weight
Compared with blank control group, * P<0.05, * * P<0.01, * * * P<0.001
Influence of the 2 Qi chrysanthemum capsule of table to second batch mouse weight
Compared with blank control group, * P<0.05, * * P<0.01, * * * P<0.001
(2) influence of the Qi chrysanthemum capsule to the mice burden swimming time
The result shows that each dosage group mouse of Qi chrysanthemum capsule bears a heavy burden, the average swim time under the conditions of 5% is considerably longer than sky
White control group, and the significant meaning of the difference of high dose and middle dose group and blank control group.It the results are shown in Table 3 and Fig. 1.
Influence (X ± S, second) of the 3 Qi chrysanthemum capsule of table to the mice burden swimming time
Compared with blank control group, * P<0.05, * * P<0.01
(3) influence of the Qi chrysanthemum capsule to mice serum urea nitrogen content
The experimental results showed that each dosage group mouse of Qi chrysanthemum capsule serum after not swimming with a load attached to the body 90min, rest 60min is urinated
Plain nitrogen relatively decreases with blank control group, but no significant difference, is shown in Table 4 and Fig. 2.
Influence (X ± S, mmol/l) of the 4 Qi chrysanthemum capsule of table to mice serum urea nitrogen content
(4) influence of the Qi chrysanthemum capsule to mouse Serum lactic acid content
The surveyed blood lactase acid value that will immediately take a blood sample after swimming makes the difference with the surveyed blood lactase acid value of blood sampling before swimming, for blood breast after swimming
Sour lift-off value (lactic acid lift-off value) reflects lactic acid ramp-up rate；Stop after the surveyed blood lactase acid value of blood sampling and swimming immediately after swimming
The surveyed blood lactase acid value of breath 20min blood samplings makes the difference, for rest 20min blood lactase acids drop-out value (lactic acid drop-out value) after swimming, reflection breast
Sour release rate.The result shows that after each dosage group mouse swimming of Qi chrysanthemum capsule blood lactase acid lift-off value with blank control group without apparent
Difference, and rest 20min blood lactase acids drop-out value and the obvious increase of blank control group after each dosage group swimming of Qi chrysanthemum capsule,
The significant meaning of the difference of middle high dose group and blank control group.It the results are shown in Table 5 and Fig. 3.
Influence (X ± S, mmol/l) of the 5 Qi chrysanthemum capsule of table to mouse Serum lactic acid content
Compared with blank control group, * P<0.05
2.3 conclusion
(1) swimming power exhausts experiment
The results show that each dosage group mouse of Qi chrysanthemum capsule is in the case of the sheet lead for 5% weight of bearing a heavy burden, swimming power exhausts the time
It is considerably longer than blank control group, and the significant meaning of the difference of high dose and middle dose group and blank control group.Explanation
Qi chrysanthemum capsule can be obviously prolonged the walking weight load of mouse, there is apparent antifatigue effect.During experiment, have it is following because
Element significantly affects test result.
Exercise intensity:Some mouse keep afloat and do not swim, and swimming time can be made significantly to extend, and therefore, reliably to be tied
Fruit, it is necessary to make each mouse persistently swim, can be gently agitated for around mouse with waddy.And sufficient instruction should be done before experiment
Practice swimming test.
It bears a heavy burden:It bears a heavy burden smaller, buoyancy is bigger, and mouse swimming time is longer.This experiment determines heavy burden object by preliminary experiment
Galvanized wire weight is the 5% of mouse weight, and ensures the consistent of mouse tail binding position as far as possible during the experiment.
The number of mice being once put into swimming trunk:The number of mice being put into simultaneously in one water tank cannot be too many, otherwise mutually
It bears against, step on and touch, be easy to choke water and shorten swimming time.Therefore, this number of mice for testing in a water tank while entering water is 2
Only, it ensure that the accurate of experimental result.
(2) serum urea nitrogen determination is tested
When run duration is less than 30min, the less participation energy supply of protein, blood urea nitrogen changes unobvious, larger load fortune
After dynamic, blood urea nitrogen just obviously increases, and protein catabolism reinforcement can be extended to post exercise rest period, blood urea nitrogen
Can after exercise the long period persistently increase.Therefore, the run duration-swimming 90min for selecting larger load is tested in this experiment；Choosing
Select 30 DEG C of suitable temperature, at this temperature mouse can swim as defined in the time died without lethal.Rest 60min takes a blood sample after swimming,
Blood urea nitrogen level is still higher at this time.
The experimental results showed that each dosage group mouse of Qi chrysanthemum capsule serum after not swimming with a load attached to the body 90min, rest 60min is urinated
Plain nitrogen relatively decreases with blank control group, but no significant difference.It is certain by subtracting to illustrate that Qi chrysanthemum capsule has
Few protein depletion acts on not notable to antifatigue effect.
(3) blood lactase acid measures experiment
Only strenuous exercise, lactic acid yield just increase in short-term, and marathon movement can not make blood lactase acid horizontal
It increases.Therefore this experiment selection short time strenuous exercise measures experiment to carry out blood lactase acid.After mice burden swimming 6min immediately
Take a blood sample the blood lactase acid value that measures, and before swimming blood lactase acid value difference, can reflect blood lactase acid ramp-up rate；It rests with after swimming
The difference for the blood lactase acid value that 20min is measured, can reflect blood lactate removal speed.
Test result shows after each dosage group mouse swimming of Qi chrysanthemum capsule blood lactase acid ramp-up rate with blank control group without bright
Significant difference is different, and rest 20min blood lactate removals speed and the obvious increasing of blank control group after each dosage group swimming of Qi chrysanthemum capsule
Add, the significant meaning of difference of wherein high dose group and blank control group.Illustrate that Qi chrysanthemum capsule can be by accelerating blood breast
Acid elimination and play antifatigue effect.
Embodiment 3：Its Chinese medicine composition weight quota be：25 parts of rhodiola root, 25 parts of the fruit of Chinese wolfberry, 20 parts of chrysanthemum and Chinese yam
20 parts.
A, the fruit of Chinese wolfberry is carried 2 times with 70% ethyl alcohol, 10 times of amounts, each reflux extracting time 3 hours, and 70 DEG C of extracting solution concentrations obtain
Medicinal extract, until relative density 1.35, residue is spare.
B, residue mixes in chrysanthemum, rhodiola root and above-mentioned steps A, measures water refluxing extraction 3 times with 10 times, 3 hours every time, closes
And extracting solution, 70 DEG C are concentrated to give medicinal extract, until relative density 1.35.
C, the medicinal extract for producing above-mentioned steps A and B merges, and dry cream is dried at 70 DEG C or so, and moisture is less than 3%,
It is crushed after mixing with Chinese yam, obtains mixed powder, cross 120 mesh sieve, it is canned at capsule, you can.
Embodiment 4：Its Chinese medicine composition weight quota be：60 parts of rhodiola root, 35 parts of the fruit of Chinese wolfberry, 35 parts of chrysanthemum and Chinese yam
30 parts.
A, the fruit of Chinese wolfberry is carried 2 times with 65% ethyl alcohol, 7 times of amounts, each reflux extracting time 2.5 hours, 65 DEG C of extracting solution concentrations,
Medicinal extract is obtained to relative density 1.32, residue is spare.
B, residue mixes in chrysanthemum, rhodiola root and above-mentioned steps A, and water refluxing extraction is measured 3 times with 9 times, 2.5 hours every time,
Merge extracting solution, 65 DEG C are concentrated to give medicinal extract to relative density 1.32.
C, the medicinal extract for producing above-mentioned steps A and B merges, and is dried to dry cream at 70 DEG C or so, after mixing with Chinese yam
It crushes, obtains mixed powder, cross 120 mesh sieve, it is canned at capsule, you can.
Embodiment 5：Its Chinese medicine composition weight quota be：45 parts of rhodiola root, 25 parts of the fruit of Chinese wolfberry, 20 parts of chrysanthemum and Chinese yam
30 parts.
A, the fruit of Chinese wolfberry 65% ethyl alcohol, 6 times of amounts are carried 2 times, each reflux extracting time keeps negative at 2.5 hours, 70 DEG C
0.04MPa concentrations are pressed, obtain medicinal extract to relative density 1.32, residue is spare.
B, residue mixes in chrysanthemum, rhodiola root and above-mentioned steps A, and water refluxing extraction is measured 2 times with 6 times, 2.5 hours every time,
Merge extracting solution, at 70 DEG C, negative pressure 0.04MPa is kept to be concentrated into relative density 1.32.
C, the medicinal extract for producing above-mentioned steps A and B merges, and is dried to moisture at 70 DEG C and is less than 10% one-tenth dry cream,
It is crushed after mixing with Chinese yam, obtains mixed powder, cross 120 mesh sieve, it is canned at capsule, you can.
Embodiment 6：The weight quota of the Chinese medicine constituent is：35 parts of rhodiola root, 35 parts of the fruit of Chinese wolfberry, 10 parts of chrysanthemum
With 10 parts of Chinese yam, it is spare that rhodiola root, the fruit of Chinese wolfberry, chrysanthemum are first crushed to 20 mesh or less respectively.
A, the fruit of Chinese wolfberry is taken to be carried 2 times at 60% ethyl alcohol, 10 times of 60 DEG C of amounts, each reflux extracting time 3 hours, by extracting solution
It is 1.30 that relative density is concentrated at 0.35MPa60 DEG C, obtains medicinal extract, and residue is spare.
B, residue in chrysanthemum, rhodiola root and above-mentioned steps A is mixed, water refluxing extraction is measured 2 times with 8 times, 2 hours every time,
Merge extracting solution, it is 1.30 to be concentrated to give medicinal extract that relative density is concentrated at 0.35MPa60 DEG C.
C, the medicinal extract for producing above-mentioned steps A and B merges, and the dry cream that water content is less than or equal to 8% is dried at 65 DEG C,
It is crushed after mixing with Chinese yam, crosses 80~120 mesh sieve, obtain mixed powder, it is canned at capsule, you can.
Embodiment 7：The weight quota of the Chinese medicine constituent is：50 parts of rhodiola root, 30 parts of the fruit of Chinese wolfberry, 25 parts of chrysanthemum
With 10 parts of Chinese yam, it is spare that rhodiola root, the fruit of Chinese wolfberry, chrysanthemum are first crushed to 40 mesh or less respectively.
A, the fruit of Chinese wolfberry is taken to be carried 3 hours with 50% ethyl alcohol, 10 times of amounts, extracting solution is dense under 0.035MPa negative pressure temperature 70 Cs
It is reduced to relative density 1.34 and obtains medicinal extract, residue is spare.
B, residue in chrysanthemum, rhodiola root and above-mentioned steps A is mixed, measures water refluxing extraction 3 times at 60 DEG C with 5 times, often
Secondary 2 hours, merge extracting solution, relative density 1.33 is concentrated at 65 DEG C of 0.035MPa negative pressure and obtains medicinal extract.
C, the medicinal extract for producing above-mentioned steps A and B merges, and is dried to moisture at 65 DEG C and is less than 7% one-tenth dry cream, mixed with Chinese yam
It is crushed after closing uniformly, sieves with 100 mesh sieve, obtain mixed powder, it is canned at capsule, you can.
Embodiment 8：The weight quota of the Chinese medicine constituent is：50 parts of rhodiola root, 20 parts of the fruit of Chinese wolfberry, 20 parts of chrysanthemum
With 20 parts of Chinese yam, it is spare that rhodiola root, the fruit of Chinese wolfberry, chrysanthemum are first crushed to 60 mesh or less respectively.
A, the fruit of Chinese wolfberry is taken to be carried 2 times with 55% ethyl alcohol, 6 times of amounts, each reflux extracting time 3 hours, extracting solution is in 0.04MPa
It is concentrated into relative density 1.35 at a temperature of 70 DEG C of negative pressure and obtains medicinal extract, residue is spare.
B, residue in chrysanthemum, rhodiola root and above-mentioned steps A is mixed, measures water refluxing extraction 2 times at 55 DEG C with 10 times, often
Secondary 2 hours, merge extracting solution, be concentrated at 70 DEG C of 0.04MPa negative pressure relative density 1.35 medicinal extract.
C, the medicinal extract for producing above-mentioned steps A and B merges, and is dried to moisture at 70 DEG C and is less than 6% one-tenth dry cream, mixed with Chinese yam
It is crushed after closing uniformly, crosses 120 mesh sieve, obtain mixed powder, it is canned at capsule, you can.
Embodiment 9：The weight quota of the Chinese medicine constituent is：50 parts of rhodiola root, 25 parts of the fruit of Chinese wolfberry, 20 parts of chrysanthemum
With 10 parts of Chinese yam, it is spare that rhodiola root, the fruit of Chinese wolfberry, chrysanthemum are first crushed to 40 mesh or less respectively.
A, the fruit of Chinese wolfberry is taken to be carried 2 times with 70% ethyl alcohol, 5 times of amounts, extracting solution is concentrated in by each reflux extracting time 3 hours
It is concentrated into relative density 1.30 at 70 DEG C of 0.042MPa negative pressure and obtains medicinal extract, residue is spare.
B, residue in chrysanthemum, rhodiola root and above-mentioned steps A is mixed, measures water refluxing extraction 3 times at 65 DEG C with 5 times, often
Secondary 1 hour, merge extracting solution, relative density 1.30 is concentrated at 70 DEG C of 0.045MPa negative pressure and obtains medicinal extract.
C, the medicinal extract for producing above-mentioned steps A and B merges, and is dried to moisture at 65 DEG C and is less than 8% one-tenth dry cream, mixed with Chinese yam
It is crushed after closing uniformly, crosses 80 mesh sieve, obtain mixed powder, it is canned at capsule, you can.
Embodiment 10：The weight quota of the Chinese medicine constituent is：45 parts of rhodiola root, 30 parts of the fruit of Chinese wolfberry, chrysanthemum 15
10 parts of part and Chinese yam, it is spare to be first crushed to 15 mesh or less respectively by rhodiola root, the fruit of Chinese wolfberry, chrysanthemum.
A, the fruit of Chinese wolfberry is taken to be carried 2 times with 60% ethyl alcohol, 8 times of amounts, each reflux extracting time 3 hours, extracting solution is in 0.04MPa
It is concentrated into relative density 1.35 at 70 DEG C of negative pressure and obtains medicinal extract, residue is spare.
B, residue in chrysanthemum, rhodiola root and above-mentioned steps A is mixed, returns the extraction 2 times that flows down at 70 DEG C with 10 times of amount water, often
Secondary 2 hours, merge extracting solution, relative density 1.3 is concentrated at 70 DEG C of 0.04MPa negative pressure and obtains medicinal extract.
C, the medicinal extract for producing above-mentioned steps A and B merges, and is dried to moisture at 70 DEG C and is less than 6% one-tenth dry cream, mixed with Chinese yam
It is crushed after closing uniformly, sieves with 100 mesh sieve, obtain mixed powder, it is canned at capsule, you can.
It the above is only the preferred embodiment of the present invention, it is noted that above-mentioned preferred embodiment is not construed as pair
The limitation of the present invention, protection scope of the present invention should be subject to claim limited range.For the art
For those of ordinary skill, without departing from the spirit and scope of the present invention, can also make several improvements and modifications should also regard
For protection scope of the present invention.
Claims (3)
1. a kind of preparation method of health care product used for relieving physical fatigue, which is characterized in that using Chinese medicine rhodiola root, matrimony vine
Prepared by son, chrysanthemum and Chinese yam, in turn include the following steps：
A, the fruit of Chinese wolfberry is taken to be carried 1~2 time with 50%~70% ethyl alcohol, 5~10 times of amounts, each reflux extracting time 1~3 hour, extraction
Liquid concentrates, and obtains medicinal extract, residue is spare；
B, residue in chrysanthemum, rhodiola root and above-mentioned steps A is mixed, with 5~10 times of amount water refluxing extractions 2~3 times, every time 1~3
Hour, merge extracting solution, is concentrated to give medicinal extract；
C, the medicinal extract for producing above-mentioned steps A and B merges, and the dry cream that moisture is less than 9% is dried at 50 DEG C~70 DEG C, with Chinese yam
It crushes after mixing, crosses 80~120 mesh and sieve to obtain mixed powder, it is canned at capsule, you can；
The weight quota of the Chinese medicine constituent is：45-55 parts of rhodiola root, 25-35 parts of the fruit of Chinese wolfberry, 20-30 parts of chrysanthemum and
8-12 parts of Chinese yam；
Extracting solution thickening temperature described in step A is 50 DEG C~70 DEG C with the extracting solution thickening temperature described in step B；
The medicinal extract relative density that medicinal extract that step A is produced, step B are produced is 1.30~1.35.
2. the preparation method of health care product used for relieving physical fatigue as described in claim 1, which is characterized in that the Chinese medicine
The weight quota of material constituent is：10 parts of 50 parts of rhodiola root, 30 parts of the fruit of Chinese wolfberry, 25 parts of chrysanthemum and Chinese yam.
3. a kind of health care product used for relieving physical fatigue, which is characterized in that prepared by method as claimed in claim 1 or 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510182615.5A CN104721475B (en) | 2015-04-16 | 2015-04-16 | A kind of health care product used for relieving physical fatigue and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510182615.5A CN104721475B (en) | 2015-04-16 | 2015-04-16 | A kind of health care product used for relieving physical fatigue and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104721475A CN104721475A (en) | 2015-06-24 |
| CN104721475B true CN104721475B (en) | 2018-09-25 |
Family
ID=53446271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510182615.5A Active CN104721475B (en) | 2015-04-16 | 2015-04-16 | A kind of health care product used for relieving physical fatigue and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104721475B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108034556B (en) * | 2018-01-02 | 2021-07-13 | 云南七都酒业有限公司 | Pseudo-ginseng health-care wine and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893549A (en) * | 2014-04-21 | 2014-07-02 | 上海创隆生物技术有限公司 | Traditional Chinese medicine composition for relieving fatigue as well as preparation method and application of composition |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0873369A (en) * | 1994-09-01 | 1996-03-19 | Fuairudo:Kk | Tea for health |
-
2015
- 2015-04-16 CN CN201510182615.5A patent/CN104721475B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893549A (en) * | 2014-04-21 | 2014-07-02 | 上海创隆生物技术有限公司 | Traditional Chinese medicine composition for relieving fatigue as well as preparation method and application of composition |
Non-Patent Citations (1)
| Title |
|---|
| 红景天缓解体力疲劳作用的实验研究;张桂霞等;《医药论坛杂志》;20051231;第26卷(第23期);第48-49页，尤其是第49页3讨论 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104721475A (en) | 2015-06-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102429066B (en) | Physical strength-enhancing anti-fatigue compound Maca coffee product | |
| CN104107217B (en) | The composition that prevention or treatment are still drank after a night | |
| CN101669629B (en) | Natural plant type functional health-care sports drink and manufacturing method thereof | |
| CN107929420A (en) | Improve energy and blood of human body function and improve the Chinese medicine composition and detection method of immunity | |
| CN102907604A (en) | Health-care product having effects of reducing blood sugar and pressure, losing weight, relaxing bowels, maintaining beauty and resisting fatigue and production process thereof | |
| CN107874183A (en) | A kind of improvement male's sexual, antifatigue composition and preparation method thereof | |
| CN101248880A (en) | Fatigue resistant sport drink and method of preparing the same | |
| CN104336174A (en) | Rhodiola rosea and milk vinegar contained green tea health beverage | |
| CN101327015A (en) | Bone-tonifying growth-encouraging rice flour and formulating method thereof | |
| CN101703296A (en) | Pleurotus citrinopileatus drink and preparation method thereof | |
| CN103155985B (en) | Rhizoma polygonati nutrition powder and preparation method thereof | |
| CN106942578A (en) | A kind of natural meals for controlling purine intake and promoting uric acid excretion | |
| CN106616183A (en) | Solid beverage composition with Maca and dandelion as main agents and preparation method of solid beverage composition | |
| CN113907349A (en) | Food for nourishing heart, regulating liver, clearing heart and helping sleep and preparation method thereof | |
| CN104721475B (en) | A kind of health care product used for relieving physical fatigue and preparation method thereof | |
| CN102229877B (en) | Brewing method for pine pollen wine | |
| CN102090637A (en) | Collagen-containing compound nutritious powder | |
| CN114848727B (en) | Preparation method and application of American ginseng paste | |
| CN112076292A (en) | Powder with functions of enhancing immunity and regulating kidney yin deficiency and preparation method thereof | |
| CN103478703A (en) | Health food with fatigue resistance function and preparation method thereof | |
| CN102715609A (en) | High-energy nutrient composition | |
| CN113229431A (en) | White-meat lucid ganoderma sports beverage and preparation method thereof | |
| CN105925447B (en) | Compound health wine containing abelmoschus manihot and preparation method and application thereof | |
| CN108524850A (en) | A kind of liquor preparation for enhancing immune prevention cardiovascular and cerebrovascular disease | |
| CN109157548A (en) | It is a kind of with antifatigue and Yang strengthening function composition and preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhu Guoqiang Inventor after: Qiu Yuanjin Inventor before: Zhu Guoqiang Inventor before: Qiu Yuanjin Inventor before: Dai Xusheng |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: ZHU GUOQIANG QIU YUANJIN DAI XUSHENG TO: ZHU GUOQIANG QIU YUANJIN |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |