CN104718453B - 酸性条件下分析物测定用方法和试剂盒 - Google Patents

酸性条件下分析物测定用方法和试剂盒 Download PDF

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Publication number
CN104718453B
CN104718453B CN201380051645.1A CN201380051645A CN104718453B CN 104718453 B CN104718453 B CN 104718453B CN 201380051645 A CN201380051645 A CN 201380051645A CN 104718453 B CN104718453 B CN 104718453B
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analyte
protein
acid
sample
complex
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CN104718453A (zh
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M·因加纳斯
P·莱赫托宁
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Gyros Patent AB
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Gyros Patent AB
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
CN201380051645.1A 2012-10-03 2013-10-03 酸性条件下分析物测定用方法和试剂盒 Active CN104718453B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE1251116-8 2012-10-03
SE1251116 2012-10-03
SE1350373 2013-03-25
SE1350373-5 2013-03-25
PCT/SE2013/051161 WO2014055025A1 (en) 2012-10-03 2013-10-03 Method and kit for analyte determination at acidic conditions

Publications (2)

Publication Number Publication Date
CN104718453A CN104718453A (zh) 2015-06-17
CN104718453B true CN104718453B (zh) 2017-03-08

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US (1) US10036745B2 (https=)
EP (1) EP2904393B1 (https=)
JP (1) JP6279590B2 (https=)
CN (1) CN104718453B (https=)
WO (1) WO2014055025A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118443922A (zh) * 2016-09-06 2024-08-06 富士瑞必欧株式会社 肿瘤标记物的测定方法及测定试剂
CN117054645A (zh) * 2016-09-06 2023-11-14 富士瑞必欧株式会社 甲状腺球蛋白的测定方法及测定试剂
EP3514539B1 (en) * 2016-09-13 2024-11-20 Fujirebio Inc. Cardiac troponin assay method and assay reagent
AU2018374469B2 (en) * 2017-11-29 2022-06-16 F. Hoffmann-La Roche Ag Target interference suppressed anti-drug antibody assay
US12385913B2 (en) 2018-08-03 2025-08-12 Bristol-Myers Squibb Company Methods for detecting anti-drug antibodies
CN113960318A (zh) * 2021-09-28 2022-01-21 苏州赛分科技股份有限公司 一种基于酶联免疫的重组蛋白a测定方法及试剂盒
JP2025523802A (ja) * 2022-07-13 2025-07-25 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 分析物を検出するための弱酸性免疫アッセイ

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0213093A1 (en) * 1985-06-03 1987-03-04 Pharmacia Ab Immunoassay method for the determination of Fc-part binding bacterial polypeptides and/or corresponding antibodies
WO1991010911A1 (en) * 1990-01-19 1991-07-25 Repligen Corporation Immunoassay of protein a under acidic conditions
CN101097217A (zh) * 2006-06-29 2008-01-02 王珊珊 一种提高血清特异性生长因子免疫学测定灵敏度的技术
WO2009022001A1 (en) * 2007-08-16 2009-02-19 Novartis Ag Improvement of drug tolerance in immunogenicity testing
CN101583872A (zh) * 2006-09-14 2009-11-18 通用电气健康护理生物科学股份公司 测定待分析物浓度的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703001A (en) * 1985-10-23 1987-10-27 Synbiotics, Corporation Immunoassay for the detection of serum analytes using pH dependent chastropic acids
US5314804A (en) * 1992-03-24 1994-05-24 Serim Research Corporation Test for Helicobacter pylori
GB9809943D0 (en) 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
EP1390144A2 (en) * 2001-03-19 2004-02-25 Gyros AB Structural units that define fluidic functions
CA2441206A1 (en) 2001-03-19 2002-09-26 Gyros Ab Characterization of reaction variables
EP2281633A1 (en) 2001-08-28 2011-02-09 Gyros Patent Ab Retaining microfluidic microcavity and other microfluidic structures
JP2006503547A (ja) * 2002-02-11 2006-02-02 アレクシオン ファーマシューティカルズ， インコーポレイテッド 生物兵器防衛のための免疫療法
SE0200943D0 (sv) 2002-03-25 2002-03-25 Amersham Biosciences Ab Mutant protein
JP4115728B2 (ja) * 2002-03-26 2008-07-09 デンカ生研株式会社 フロースルー式検査法用組成物、これを用いたキット及び検査法
EP1509760A1 (en) * 2002-05-31 2005-03-02 Gyros AB Detector arrangement based on surface plasmon resonance
SE0300822D0 (sv) 2003-03-23 2003-03-23 Gyros Ab A collection of Micro Scale Devices
JP5171034B2 (ja) 2003-03-23 2013-03-27 ユィロス・パテント・アクチボラグ 充填済みのマイクロスケール装置
US8263415B2 (en) * 2006-09-14 2012-09-11 Ge Healthcare Bio-Sciences Ab Method of determining analyte concentration
WO2008043075A2 (en) * 2006-10-05 2008-04-10 Wyeth Compositions for the treatment of scleritis
EP2274624B1 (en) * 2008-04-03 2011-11-09 F. Hoffmann-La Roche AG Pegylated insulin-like-growth-factor assay
DK2329266T3 (en) * 2008-09-11 2016-07-18 Pasteur Institut MONITORING AND INHIBITING INFECTION WITH HUMAN IMMUNE DEFECT VIRUS BY MODULATING HMGB1-DEPENDENT TRACTOR OF HIV-1 REPLICATION AND PERSISTENCE
US8546149B2 (en) 2010-08-27 2013-10-01 Intervet Inc. Potency test for vaccine formulations
DK2676137T3 (en) 2011-02-17 2015-01-19 Nestec Sa TESTS TO DETECT AUTO ANTIBODIES FOR ANTI-TNF PHARMACEUTICALS
AU2013219968B2 (en) 2012-02-15 2018-11-08 Biocon Limited A process for detection and optional quantification of an analyte

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0213093A1 (en) * 1985-06-03 1987-03-04 Pharmacia Ab Immunoassay method for the determination of Fc-part binding bacterial polypeptides and/or corresponding antibodies
WO1991010911A1 (en) * 1990-01-19 1991-07-25 Repligen Corporation Immunoassay of protein a under acidic conditions
CN101097217A (zh) * 2006-06-29 2008-01-02 王珊珊 一种提高血清特异性生长因子免疫学测定灵敏度的技术
CN101583872A (zh) * 2006-09-14 2009-11-18 通用电气健康护理生物科学股份公司 测定待分析物浓度的方法
WO2009022001A1 (en) * 2007-08-16 2009-02-19 Novartis Ag Improvement of drug tolerance in immunogenicity testing

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
An acid dissociation bridging ELISA for detection of antibodies directed against therapeutic proteins in the presence of antigen;Aaron Patton 等;《Journal of Immunological Methods 》;20050725;第304卷;189-195 *
An Affinity Capture Elution (ACE) assay for detection of anti-drug antibody to monoclonal antibody therapeutics in the presence of high levels of drug;James S. Bourdage 等;《Journal of Immunological Methods》;20070727;第327卷;10-17 *
Detection of antibodies against therapeutic proteins in the presence of residual therapeutic protein using a solid-phase extraction with acid dissociation (SPEAD) sample treatment prior to ELISA;Holly W. Smith 等;《Regulatory Toxicology and Pharmacology》;20070807;第49卷;230-237 *
Improvement of drug tolerance in immunogenicity testing by acid treatment on Biacore;Denise Sickert 等;《Journal of Immunological Methods》;20080214;第334卷;29-36 *

Also Published As

Publication number Publication date
US20150268238A1 (en) 2015-09-24
JP2015531487A (ja) 2015-11-02
EP2904393A1 (en) 2015-08-12
WO2014055025A1 (en) 2014-04-10
JP6279590B2 (ja) 2018-02-14
EP2904393A4 (en) 2016-05-04
CN104718453A (zh) 2015-06-17
US10036745B2 (en) 2018-07-31
EP2904393B1 (en) 2018-11-28

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