CN104713614A - Device and method for detecting liquid level - Google Patents
Device and method for detecting liquid level Download PDFInfo
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- CN104713614A CN104713614A CN201510124234.1A CN201510124234A CN104713614A CN 104713614 A CN104713614 A CN 104713614A CN 201510124234 A CN201510124234 A CN 201510124234A CN 104713614 A CN104713614 A CN 104713614A
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Abstract
The invention discloses a device and method for detecting the liquid level. The device comprises a liquid level detecting mechanism used for detecting the liquid level, a liquid circuit cleaning mechanism used for maintaining gas in a gas cavity to be constant and a control system used for controlling the liquid level detecting mechanism and the liquid circuit cleaning mechanism. The liquid level detecting mechanism and the liquid circuit cleaning mechanism are connected with the control system. According to the method for detecting the liquid level by analyzing changes in the pressure in a liquid sucking pipe, the method and device for detecting the liquid level are simple and stable in structure and high in accuracy and reliability, the liquid level detection sensitivity is improved, and convenience is brought to a user.
Description
Technical field
The present invention relates to liquid level field of sensing technologies, particularly relate to a kind of liquid level sensor and detection method.
Background technology
Chemical illumination immunity analysis instrument is the self-reacting device measuring some chemical composition in blood, reagent and sample are filled in reaction cup make it react to each other, carry out automatic analysis to its reacted reactant liquor, device has liquid filling device reagent and sample are filled in reaction cup.
Filling apparatus most at present all adopts reusable stainless pin or other conductor to be detected liquid level by the mode of capacitance detecting, realize the filling to reagent and sample, annotated rear it is cleaned after reuse, there is certain cross pollution.But in the immunization program test that test concentrations scope is wide, the cross pollution between reagent and sample is particularly important.
Therefore, prior art has yet to be improved and developed.
Summary of the invention
The technical problem to be solved in the present invention is, for the above-mentioned defect of prior art, adopt disposable pipette, by carrying out the method for level detection to the analysis of pressure change in pipette, there is provided that a structure is simple, stable, accuracy and the high liquid level checking method of reliability and device, improve the sensitivity of level detection.
The technical scheme that technical solution problem of the present invention adopts is as follows:
A kind of liquid level sensor, wherein, comprise: for detecting the detecting liquid level mechanism of liquid level, for maintaining the constant fluid path wiper mechanism of gas in air cavity, for controlling the control system of detecting liquid level mechanism and fluid path wiper mechanism, described detecting liquid level mechanism, described fluid path wiper mechanism are connected with described control system respectively;
Described detecting liquid level mechanism comprises the pipette for imbitition, for installing the probe of described pipette, for the gas circuit pipe of gas circulation, for the pressure transducer of detected pressures, and the parameter of pressure transducer is carried out the pressure detection circuit that processes, described pipette connects described probe, and described probe is connected with described pressure transducer by described gas circuit pipe, described pressure transducer is connected with described pressure detection circuit, described pressure transducer also connection control system;
Described fluid path wiper mechanism comprises the water system for providing water for cleaning, for the solenoid valve whether water for cleaning controlling water system circulates, for supplying the ram pump of engine pressure for liquid carrying, for the influidic pipe of water for cleaning circulation, and the water for cleaning in influidic pipe is entered the fluid path pin of probe, described water system connects described control system and described solenoid valve respectively, described ram pump connects described control system, described solenoid valve and described influidic pipe respectively, and described influidic pipe connects fluid path pin.
Described liquid level sensor, wherein, described solenoid valve is 2/2-way solenoid valve.
Described liquid level sensor, wherein, described fluid path pin one end with between described influidic pipe by being with the joint of pipe collar to be connected, the other end is positioned at described probe.
Described liquid level sensor, wherein, described gas circuit pin one end with between described gas circuit pipe by being with the joint of pipe collar to be connected, the other end is positioned at described probe.
Described liquid level sensor, wherein, described gas circuit pipe is connected by flexible pipe with between described pressure transducer.
Described liquid level sensor, wherein, the length of described fluid path pin is longer than the length of described gas circuit pin, and described gas circuit pin is in the housing of described probe, and described fluid path pin is in the outside of the housing of probe.
Described liquid level sensor, wherein, the voltage signal that described pressure detection circuit also comprises for being obtained by pressure transducer carries out amplifying signal amplifier.
Described liquid level sensor, wherein, described control system also comprises storer, for storing voltage signal values corresponding to pressure that pressure detection circuit detects.
Based on the detection method of liquid level sensor described above, wherein, comprise the following steps:
The pressure change of S1, collection pipette interior;
S2, pipette slowly decline, and gather force value simultaneously, export corresponding voltage signal values according to the change of pressure every a schedule time;
S3, the voltage signal values of sampled point collection come in real time and the voltage signal values of the first sample point compare, and calculate the changing value of voltage signal, compare with first threshold again, if when being greater than first threshold, then output detections is to liquid level signal, if be less than first threshold, performs step S4;
S4, the air pressure change value judging before the 3rd sampled point and the second sampled point, then compare with first threshold, if when being greater than threshold value first threshold, then output detections is to liquid level signal, is then less than first threshold and then performs step S5;
Whether S5, the ratio of pressure differential judged before sampling time and the first sampled point to current sampling point are less than Second Threshold, if error within the specific limits, then output detections is to liquid level signal.
Described liquid level checking method, wherein, when liquid level sensor suspends in atmosphere, the magnitude of voltage that the pressure that liquid level detection circuit detects is corresponding, is designated as P1, and the pressure produced after setting pipette enters into liquid is designated as P2, first threshold is set to L1, first threshold L1=P2-P1;
The pressure differential that if △ v1 is pipette when entering into liquid level from air between neighbouring 2, pressure differential is designated as △ P, △ P=P2-P1, and △ t is sampling time interval, and Second Threshold is set to L2, L2=△ v1/ △ t.
The invention provides a kind of liquid level sensor and detection method, described device comprises the detecting liquid level mechanism for detecting liquid level, for maintaining the constant fluid path wiper mechanism of gas in air cavity, for controlling the control system of detecting liquid level mechanism and fluid path wiper mechanism, described detecting liquid level mechanism, described fluid path wiper mechanism are connected with described control system respectively.The present invention, by carrying out the method for level detection to the analysis of pressure change in pipette, provides that a structure is simple, stable, accuracy and the high liquid level checking method of reliability and device, improves the sensitivity of level detection.
Accompanying drawing explanation
Fig. 1 is the structural representation of the preferred embodiment of a kind of liquid level sensor of the present invention.
Fig. 2 is the level detection analogue signal amplitude-displacement waveform schematic diagram of a kind of embodiment of a kind of liquid level checking method of the present invention.
Fig. 3 is the process flow diagram of the Application Example of a kind of liquid level checking method of the present invention.
1, water system 2,2/2-way solenoid valve 3, ram pump 4, reaction cup 5, pipette 6, probe 7, pressure transducer 8, flexible pipe 9, gas circuit pipe 10, joint 11, pipe collar 12, influidic pipe 13, fluid path pin 14, gas circuit pin 15, pressure detection circuit 16, control system.
Embodiment
For making object of the present invention, technical scheme and advantage clearly, clearly, developing simultaneously referring to accompanying drawing, the present invention is described in more detail for embodiment.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
The invention provides a kind of liquid level sensor, wherein, comprise: for detecting the detecting liquid level mechanism of liquid level, for maintaining the constant fluid path wiper mechanism of gas in air cavity, for controlling the control system of detecting liquid level mechanism and fluid path wiper mechanism, described detecting liquid level mechanism, described fluid path wiper mechanism are connected with described control system respectively.
Particularly, as shown in Figure 1, described detecting liquid level mechanism comprises the pipette 5 for imbitition, for installing the probe 6 of described pipette, for the gas circuit pipe 9 of gas circulation, for the pressure transducer 7 of detected pressures, and the parameter of pressure transducer 7 is carried out the pressure detection circuit 15 that processes, described pipette 5 connects described probe 6, described probe 6 is connected with described pressure transducer 7 by described gas circuit pipe 9, described pressure transducer 7 is connected with described pressure detection circuit 15, and described pressure transducer 7 is connection control system 16 also.
Described fluid path wiper mechanism comprises the water system 1 for providing water for cleaning, for the solenoid valve 2 whether water for cleaning controlling water system circulates, for supplying the ram pump 3 of engine pressure for liquid carrying, for the influidic pipe 12 of water for cleaning circulation, and the water for cleaning in influidic pipe is entered the fluid path pin 13 of probe, described water system 1 connects described control system 16 and described solenoid valve 2 respectively, described ram pump 3 connects described control system 16, described solenoid valve 2 and described influidic pipe 12 respectively, and described influidic pipe 12 also connects fluid path pin 13.
During concrete enforcement, described solenoid valve 2 is 2/2-way solenoid valve.
During concrete enforcement, the present invention, in order to be convenient to unloading after sample liquid of having annotated, avoids cross pollution.Described pipette adopts disposable pipette.Probe 6 one end by fluid path pin 13 and gas circuit pin 14 fixing and airtight, it is outer and form an air cavity with disposable pipette 5 that fluid path pin 13 and gas circuit pin 14 are exposed mouth by the other end, when 2/2-way solenoid valve 2 cuts out, after being full of liquid in ram pump 3 and fluid path pin 13, pressure transducer 7 and disposable pipette 5 form the air cavity of a path.When disposable pipette 5 enters liquid level from air, the pressure that liquid level is produced passes to pressure transducer 7 by air cavity.Disposable pipette 5 is installed on probe 6, is convenient to unloading, avoids cross pollution after sample of having annotated.Control system 16, water system 1,2/2-way solenoid valve 2, ram pump 3, influidic pipe 12 and fluid path pin 13 constitute fluid path wiper mechanism.Wherein the residual gas in fluid path pin 13 is discharged, ensure that the gas of air cavity during each detecting liquid level is constant, be conducive to the stability of detecting liquid level.
Particularly, described fluid path pin 13 one end with between described influidic pipe 12 by being with the joint 10 of pipe collar 11 to be connected, the other end is positioned at described probe 6.
Particularly, described gas circuit pin 14 one end with between described gas circuit pipe 9 by being with the joint 10 of pipe collar 11 to be connected, the other end is positioned at described probe 6.
During concrete enforcement, be connected by flexible pipe 8 between described gas circuit pipe 9 with described pressure transducer 7.
The length of described fluid path pin 13 is longer than the length of described gas circuit pin 14, and described gas circuit pin 14 is in the housing of described probe 6, and described fluid path pin 13 is in the outside of the housing of probe 6.
The voltage signal that described pressure detection circuit 15 also comprises for being obtained by pressure transducer 7 carries out amplifying signal amplifier.
Particularly, described control system 16 also comprises storer, for storing voltage signal values corresponding to pressure that pressure detection circuit detects.
Present invention also offers a kind of detection method based on liquid level sensor described above, wherein, comprise the following steps:
The pressure change of S1, collection pipette interior;
S2, pipette slowly decline, and gather force value simultaneously, export corresponding voltage signal values according to the change of pressure every a schedule time;
S3, the voltage signal values of sampled point collection come in real time and the voltage signal values of the first sample point compare, and calculate the changing value of voltage signal, compare with first threshold again, if when being greater than first threshold, then output detections is to liquid level signal, if be less than first threshold, performs step S4;
S4, the air pressure change value judging before the 3rd sampled point and the second sampled point, then compare with first threshold, if when being greater than threshold value first threshold, then output detections is to liquid level signal, is then less than first threshold and then performs step S5;
Whether S5, the ratio of pressure differential judged before sampling time and the first sampled point to current sampling point are less than Second Threshold, if error within the specific limits, then output detections is to liquid level signal.
Described liquid level checking method, wherein, when liquid level sensor suspends in atmosphere, the magnitude of voltage that the pressure that liquid level detection circuit detects is corresponding, is designated as P1, and the pressure produced after setting pipette enters into liquid is designated as P2, first threshold is set to L1, first threshold L1=P2-P1;
The pressure differential that if △ v1 is pipette when entering into liquid level from air between neighbouring 2, pressure differential is designated as △ P, △ P=P2-P1, and △ t is sampling time interval, and Second Threshold is set to L2, L2=△ v1/ △ t.
Sampling interval duration in the present invention is adjustable, preferential adopted 100ms.
Sampled point in often inventing particularly can be sampled by the sampling time, also can sample according to sampled distance.
The present invention also provides a kind of level detection analogue signal amplitude-displacement oscillogram of embody rule embodiment of liquid level checking method, as shown in Figure 2, comprise start zero point be s0, the first sampling point position s1, the second sampling point position s2, interval sampling distance △ s1, sampled point s1 place air pressure V1, sampled point s2 place air pressure V2, unit interval displacement △ t, the draught head △ v1 of unit interval; The atmospheric pressure value that Real-time Collection comes and sampled point s1 place air pressure V1 compare, and calculate air pressure change value, then compare with threshold value 1, when being greater than threshold value 1, representing and liquid level detected.Namely the distance that the distance that △ s1 equals V2 to V1 equals V2 ˊ to V1 ˊ equals the parallel distance at equal intervals between 2 slided backward, the force value of wherein getting △ s1 point-to-point transmission compares, if the difference of the force value of 2 is greater than threshold value 1, then represents and liquid level detected.△ v1 is the pressure differential between adjacent 2 that also move in parallel backward from s1 point, △ t is the mistiming between adjacent 2, when entering liquid from gas, because air pressure has a sudden change, by calculating the rate of change △ v1/ △ t of air pressure, thus judge whether liquid level to be detected, when rate of change is greater than threshold value 2, represents and liquid level detected.
The first force value in described computing unit judges from the S1 of position, second force value judges from the S2 of position, and the first force value and the second force value slide backward sampling compare, if two comparing voltage value are greater than threshold value 1 output detections to liquid level signal so that △ s1 are parallel; Particularly, described Pressure Analysis position, from S1, because s0 to the s1 firm setting in motion district that is mechanism, belongs to unstable region.
Wherein, when detecting liquid level mechanism suspends in atmosphere, pressure transducer pressure is standard atmospheric pressure, is designated as P1, and the pressure that set mechanism produces after entering into liquid is designated as P2, threshold value 1=P2-P1.
The pressure differential that if △ v1 is pipette when entering into liquid level from air between neighbouring 2, △ t is the mistiming between adjacent 2, threshold value 2=△ v1/ △ t.
Concrete enforcement, described sampling interval preferably 100ms, sampled distance can be set as 0.1mm, and pipette at the uniform velocity moves downward.And concrete sampling time interval also can be determined according to actual conditions, the distance of sampling also can be determined according to the distance of pipette movement.
Particularly, described threshold value 1 is adjustable, and threshold value 2 is adjustable, and threshold value can be two or more, and this detection method only uses two threshold values.
Present invention also offers a kind of process flow diagram of Application Example of liquid level checking method, as shown in Figure 3, described method comprises:
Step S10, beginning, perform step S20 afterwards;
Step S20, disposable pipette get a force value Vi stored in array every △ t, and particularly, control system controls to carry out pressure acquisition while disposable pipette moves down, and △ s samples 1 time, by the force value Vi of collection stored in array.Perform step S30 afterwards;
Step S30, disposable pipette move to s1 place and record force value V1 herein, move to s2 place and record force value V2 herein, perform step S40 afterwards;
Step S40, judge whether Vi-V1 is greater than threshold value 1, if so, then perform step S70; If not, then step S20 is performed;
Step S50, judge whether V2-V1 is greater than threshold value 1, if it is perform step S70, if not, then perform step S20;
Step S60, judge whether △ v1/ △ t is greater than threshold value 2, particularly, △ v1/ △ t is the rate of change of air pressure, and when pipette enters liquid from air, air pressure has a sudden change, when the rate of change △ v1/ △ t of air pressure is greater than threshold value 2, then represents and liquid level detected.If so, then perform step S70 if not, then perform step S20;
Step S70, output detections, to liquid level signal, perform step S70 afterwards;
Step S80, end.
In sum, the invention provides a kind of liquid level sensor and detection method, described device comprises the detecting liquid level mechanism for detecting liquid level, for maintaining the constant fluid path wiper mechanism of gas in air cavity, for controlling the control system of detecting liquid level mechanism and fluid path wiper mechanism, described detecting liquid level mechanism, described fluid path wiper mechanism are connected with described control system respectively.The present invention, by carrying out the method for level detection to the analysis of pressure change in pipette, provides that a structure is simple, stable, accuracy and the high liquid level checking method of reliability and device, improves the sensitivity of level detection.
Should be understood that, application of the present invention is not limited to above-mentioned citing, for those of ordinary skills, can be improved according to the above description or convert, and all these improve and convert the protection domain that all should belong to claims of the present invention.
Claims (10)
1. a liquid level sensor, it is characterized in that, comprise: for detecting the detecting liquid level mechanism of liquid level, for maintaining the constant fluid path wiper mechanism of gas in air cavity, for controlling the control system of detecting liquid level mechanism and fluid path wiper mechanism, described detecting liquid level mechanism, described fluid path wiper mechanism are connected with described control system respectively;
Described detecting liquid level mechanism comprises the pipette for imbitition, for installing the probe of described pipette, for the gas circuit pipe of gas circulation, for the pressure transducer of detected pressures, and the parameter of pressure transducer is carried out the pressure detection circuit that processes, described pipette connects described probe, and described probe is connected with described pressure transducer by described gas circuit pipe, described pressure transducer is connected with described pressure detection circuit, described pressure transducer also connection control system;
Described fluid path wiper mechanism comprises the water system for providing water for cleaning, for the solenoid valve whether water for cleaning controlling water system circulates, for supplying the ram pump of engine pressure for liquid carrying, for the influidic pipe of water for cleaning circulation, and the water for cleaning in influidic pipe is entered the fluid path pin of probe, described water system connects described control system and described solenoid valve respectively, described ram pump connects described control system, described solenoid valve and described influidic pipe respectively, and described influidic pipe connects fluid path pin.
2. liquid level sensor according to claim 1, is characterized in that, described solenoid valve is 2/2-way solenoid valve.
3. liquid level sensor according to claim 1, is characterized in that, described fluid path pin one end with between described influidic pipe by being with the joint of pipe collar to be connected, the other end is positioned at described probe.
4. liquid level sensor according to claim 1, is characterized in that, described gas circuit pin one end with between described gas circuit pipe by being with the joint of pipe collar to be connected, the other end is positioned at described probe.
5. liquid level sensor according to claim 1, is characterized in that, described gas circuit pipe is connected by flexible pipe with between described pressure transducer.
6. liquid level sensor according to claim 1, is characterized in that, the length of described fluid path pin is longer than the length of described gas circuit pin, and described gas circuit pin is in the housing of described probe, and described fluid path pin is in the outside of the housing of probe.
7. liquid level sensor according to claim 1, is characterized in that, the voltage signal that described pressure detection circuit also comprises for being obtained by pressure transducer carries out amplifying signal amplifier.
8. liquid level sensor according to claim 1, is characterized in that, described control system also comprises storer, for storing voltage signal values corresponding to pressure that pressure detection circuit detects.
9., based on a detection method for liquid level sensor described in any one of claim 1-8, it is characterized in that, comprise the following steps:
The pressure change of S1, collection pipette interior;
S2, pipette slowly decline, and gather force value simultaneously, export corresponding voltage signal values according to the change of pressure every a schedule time;
S3, the voltage signal values of sampled point collection come in real time and the voltage signal values of the first sample point compare, and calculate the changing value of voltage signal, compare with first threshold again, if when being greater than first threshold, then output detections is to liquid level signal, if be less than first threshold, performs step S4;
S4, the air pressure change value judging before the 3rd sampled point and the second sampled point, then compare with first threshold, if when being greater than threshold value first threshold, then output detections is to liquid level signal, is then less than first threshold and then performs step S5;
Whether S5, the ratio of pressure differential judged before sampling time and the first sampled point to current sampling point are less than Second Threshold, if error within the specific limits, then output detections is to liquid level signal.
10. liquid level checking method according to claim 9, it is characterized in that, when liquid level sensor suspends in atmosphere, the magnitude of voltage that the pressure that liquid level detection circuit detects is corresponding, be designated as P1, the pressure produced after setting pipette enters into liquid is designated as P2, and first threshold is set to L1, first threshold L1=P2-P1;
The pressure differential that if △ v1 is pipette when entering into liquid level from air between neighbouring 2, pressure differential is designated as △ P, △ P=P2-P1, and △ t is sampling time interval, and Second Threshold is set to L2, L2=△ v1/ △ t.
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CN105004401A (en) * | 2015-08-07 | 2015-10-28 | 四川迈克生物医疗电子有限公司 | Liquid level detection device and method |
CN105067080A (en) * | 2015-08-06 | 2015-11-18 | 四川迈克生物医疗电子有限公司 | Capacitive liquid level detection device, method and system |
CN106391606A (en) * | 2016-10-17 | 2017-02-15 | 深圳开立生物医疗科技股份有限公司 | Detection instrument and reaction container cleaning method thereof |
CN109718883A (en) * | 2018-12-25 | 2019-05-07 | 迪瑞医疗科技股份有限公司 | A kind of liquid-transfering device and liquid relief method |
CN114812739A (en) * | 2022-05-07 | 2022-07-29 | 成都开图医疗系统科技有限公司 | Method for accelerating liquid level detection of pneumatic pipettor and pneumatic pipettor |
CN116989868A (en) * | 2023-06-08 | 2023-11-03 | 中元汇吉生物技术股份有限公司 | Multi-parameter fusion liquid level detection device and method |
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CN116989868A (en) * | 2023-06-08 | 2023-11-03 | 中元汇吉生物技术股份有限公司 | Multi-parameter fusion liquid level detection device and method |
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