CN104689301A - Medicine for removing striae gravidarum and preparing method for medicine for removing striae gravidarum - Google Patents
Medicine for removing striae gravidarum and preparing method for medicine for removing striae gravidarum Download PDFInfo
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- CN104689301A CN104689301A CN201510138263.3A CN201510138263A CN104689301A CN 104689301 A CN104689301 A CN 104689301A CN 201510138263 A CN201510138263 A CN 201510138263A CN 104689301 A CN104689301 A CN 104689301A
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Abstract
The invention provides a medicine for removing striae gravidarum and a preparing method for the medicine for removing the striae gravidarum. The medicine for removing the striae gravidarum comprises, by volume, 10-30 parts of autoblood and 1-5 parts of rh-Bfgf, wherein the concentration of the rh-Bfgf ranges from 7000 IU/mL to 35000 IU/mL. The preparing method includes the following steps: (A) the rh-Bfgf is diluted by normal saline into 7000 IU/mL-35000 IU/mLof solution so as to obtain the rh-Bfgf solution; (B) the autoblood and the rh-Bfgf solution are mixed, centrifugation is then carried out, red sediment on the bottom layer is removed, and the medicine is obtained. The medicine has the multiple pharmacological functions of treating the striae gravidarum, wrinkles and face sinking, humping the nose and the like; in addition, the disease treatment effective rate can reach 100%, and the treatment effect on the striae gravidarum is best.
Description
Technical field
The present invention relates to drug world, in particular to a kind of medicine of dispelling striae gravidarum and preparation method thereof.
Background technology
The formation of striae gravidarum is mainly due to trimester of pregnancy hormonal impact, in addition abdominal tympanites makes the elastic fibers of skin and collagen fiber damage or rupture, skin of abdomen is thinning to attenuate, and occurs some width difference, pink different in size or mauve wavy decorative patterns.Divide the puerperium, these decorative patterns can fade away, and leave white or argenteous glossiness cicatrix strain line, i.e. striae gravidarum.Striae gravidarum mainly appears on stomach wall, and also may appear at the places such as the interior outside of thigh, buttocks, chest, back lumbar part and arm, primipara is the most obvious.Once occur that striae gravidarum would not disappear, and striae gravidarum is difficult to prevention.But also do not have the medicine effectively can dispelling striae gravidarum at present, this badly influences figure and the physical and mental health in women puerperal.
In view of this, special proposition the present invention.
Summary of the invention
The first object of the present invention is to provide a kind of medicine of dispelling striae gravidarum, described medicine effectively can dispel striae gravidarum, its effective percentage is 100%, cures area up to more than 90%, and described medicine also can be used for augmentation rhinoplasty, wrinkle reduction and treatment Facial Depression.
The second object of the present invention is to provide a kind of described preparation method dispelling the medicine of striae gravidarum, and described preparation method is simple to operation, and obtained drug quality is homogeneous, and bioavailability is high.
In order to realize above-mentioned purpose of the present invention, the following technology therapeutic scheme of special employing:
Dispel a medicine for striae gravidarum, comprise following composition:
By volume, autoblood 10-30 part, holding up the multiple 1-5 part of Ji, and described in hold up the multiple concentration of Ji to be 7000-35000IU/mL.
Said medicine formula is simple, and raw material easily obtains, and it not only has significant curative effect to striae gravidarum, and for postpartum women brings new vitality, and this medicine also has significant curative effect to wrinkle, Facial Depression, can also be used for augmentation rhinoplasty, for painless face-lifting provides new technique.In addition, because the blood that said medicine is used is autoblood, therefore rejection can not occur, safety is high, has no side effect.In actual applications, external application for curing is advised.
In addition, prove through test, said medicine is 100% to the effective percentage of striae gravidarum, and dispels area and all can reach more than 90%; Be 100% to the effective percentage of wrinkle, dispelling area up to more than 75%, is 100% to the effective percentage of Facial Depression, and repaired area is up to more than 80%, and in three months, augmentation rhinoplasty height can reach more than 0.1cm.
Further, also comprise: by volume, triamcinolone acetonide 1-2 part.
Add triamcinolone acetonide and can prevent scar hyperplasia, suppress cicatrix growth, prevention of inflammation, and triamcinolone acetonide can form synergism occurs with other two kinds, raising curative effect, shortening treatment cycle.
Further, by volume, autoblood 10-30 part, holding up the multiple 2-3 part of Ji, and described in hold up the multiple concentration of Ji to be 11600-17500IU/mL.
This formula to striae gravidarum to dispel efficiency higher, treatment cycle is shorter.
Further, by volume, autoblood 10-30 part, holding up the multiple 3-5 part of Ji, and described in hold up the multiple concentration of Ji to be 7000-11600IU/mL.
This formula to wrinkle to dispel efficiency higher, treatment cycle is shorter.
Further, by volume, autoblood 10-30 part, holding up the multiple 1-2 part of Ji, and described in hold up the multiple concentration of Ji to be 17500-35000IU/mL.
This formula is better to the repairing effect of Facial Depression, and augmentation rhinoplasty effect is more outstanding, and treatment cycle is shorter.
Dispel a preparation method for the medicine of striae gravidarum, comprise the following steps:
Steps A: with normal saline by the described solution holding up Ji to dilute 7000-35000IU/mL again, obtains holding up Ji redissolution liquid;
Step B: by described autoblood with described hold up help redissolve liquid and mix, more centrifugal, the red precipitate of removing bottom, obtains medicine.
Above-mentioned preparation method is simple to operation, and obtained drug quality is homogeneous, and bioavailability is high.
Further, in described step B, after the red precipitate of removing bottom, also add 1-2 part triamcinolone acetonide.
Equally, adding triamcinolone acetonide can prevent scar hyperplasia, suppresses cicatrix growth, prevention of inflammation, and triamcinolone acetonide can form synergism occurs with other two kinds, raising curative effect, shortening treatment cycle.
Further, described centrifugal method is: centrifugal 6-15min under 2100-2300r/min.
Adopt above centrifugal condition both effectively can remove lipid composition in blood in non-functional erythrocyte and blood, medicine can be avoided again to solidify and affect the treatment, serum can also be made and hold up Ji multiple fully compatible, heighten the effect of a treatment mutually.
Further, after the red precipitate of the removing bottom in described step B, also comprise: at 20-30 DEG C, constant temperature places 13-17min.Can prevent medicine from solidifying like this.
Further, the method mixed in described step B is: the 0.4-0.6 first adding total amount in described autoblood Ji of holding up doubly redissolves liquid, then mix successively, centrifugal, remove the red precipitate of bottom afterwards, then the Ji of holding up adding surplus redissolves liquid.
Mixing can make to hold up Ji effectively to reside in serum again at twice, improves active constituent content.
Further, by weight percentage, the concentration of normal saline used is 0.85-0.95%.
This concentration can not produce zest to skin, and has certain bactericidal effect.
Compared with prior art, beneficial effect of the present invention is:
(1) there is the multiple drug effects such as treatment striae gravidarum, wrinkle, Facial Depression and augmentation rhinoplasty, and all can reach 100% to the effective percentage of these diseases, best to the therapeutic effect of striae gravidarum.
(2) ingredient is simple and easy to obtain, and cost is low.
(3) drug safety is high, has no side effect.
(4) preparation method of medicine is simple.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but it will be understood to those of skill in the art that the following example only for illustration of the present invention, and should not be considered as limiting the scope of the invention.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, be and can buy by commercially available the conventional products obtained.
Embodiment 1
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 1 part of Ji, and described in hold up the multiple concentration of Ji to be 7000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 2
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 5 parts of Ji, and described in hold up the multiple concentration of Ji to be 7000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 3
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 2 parts of Ji, and described in hold up the multiple concentration of Ji to be 7000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 4
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10-30 part, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 7000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 5
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 4 parts of Ji, and described in hold up the multiple concentration of Ji to be 7000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 6
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 12000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 7
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 17000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 8
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 22000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 9
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 27000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 10
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 32000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 12 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 11
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 2 parts of Ji, and described in hold up the multiple concentration of Ji to be 35000IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 6 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 12
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 11600IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 13
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 2 parts of Ji, and described in hold up the multiple concentration of Ji to be 11600IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 14
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 1.5 parts of Ji, and described in hold up the multiple concentration of Ji to be 17500IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, and added in blood by the solution after dilution, then carry out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
Embodiment 15
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 11600IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, is added in blood by the solution after dilution, then carries out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, then add 1 part of triamcinolone acetonide, can use.
Embodiment 16
Dispel a medicine for striae gravidarum, comprise following composition: by volume, autoblood 10 parts, holding up multiple 3 parts of Ji, and described in hold up the multiple concentration of Ji to be 11600IU/mL.
This medicine adopts following methods to obtain:
Normal saline dilution with 0.9% holds up Ji multiple, adding in blood of the solution after half being diluted, then carries out centrifugal, centrifuge is set as 2200 turns, and the time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, what add residue half again holds up Ji redissolution liquid, then carries out centrifugal, and centrifuge is set as 2200 turns, time is 10 minutes, rear taking-up, after removing the lipid composition in non-functional erythrocyte and blood, can use.
It is below clinical practice of the present invention example.
Dispel the case of striae gravidarum
1, Huang, female, 33 years old, 6 months medical striae gravidarum after secondary cesarean.
The first visit time: in June, 2012
Patient's readme: have pruritus during abdominal part, especially obvious with scar after the operation place.
Symptom: have a medical check-up and see, there is irregular striae gravidarum in hypogastric region, every bar striae gravidarum lines diameter about 2.5mm, hypogastric region has an obvious scar after the operation about 5 centimetres.
Therapeutic Method: extract patient's self-blood 20ml, add 1:1000 somatomedin (normal saline dilution with 0.9% holds up Ji again), after high speed centrifugation, obtain and be rich in high concentration growth factor serum liquid, inject striae gravidarum mesoderm and hypodermic layer, epidermis is being subtracted with the color of dot matrix laser lift-off striae gravidarum epidermal area, after add triamcinolone acetonide liquid (volume ratio) by 2:1 being rich in high concentration growth factor serum liquid, after mix homogeneously, outer wiping wound surface, wound surface sterilization in every 3 days is changed dressings once.Within every 3 months, repeat once by this method, did 5 times altogether, effect reaches more than 85%.0.8-1.2ml triamcinolone acetonide liquid is injected at scar after the operation place, patient is advised to press cicatrix place every day 50 times, after 60 days, outstanding cicatrix place is almost smooth, the out-of-flatness at cicatrix place is peeled off again with dot matrix, afterwards be rich in add triamcinolone acetonide liquid mix homogeneously by 1:1 in high concentration growth factor serum liquid after wipe wound surface outward, sterilization in every 3 days is changed dressings once.
2, Zhang, female, 36 years old, 5 years medical striae gravidarum after natural labor 2 tire.
The first visit time: in October, 2012
Patient's readme: abdominal pregnancy stricture of vagina is obvious, almost without diseases such as prurituss, affects attractive in appearance.
Symptom: have a medical check-up and see: irregular striae gravidarum appears in hypogastric region, and color subtracts obviously, every bar striae gravidarum lines diameter about 2mm.
Therapeutic scheme: extract patient's self-blood 20ml, add 1:1000 somatomedin (normal saline dilution with 0.9% holds up Ji again), after high speed centrifugation, obtain and be rich in high concentration growth factor serum liquid, inject striae gravidarum mesoderm and hypodermic layer, epidermis is subtracted at the color peeling off striae gravidarum epidermal area with dot matrix laser or surgical blade, after after being rich in and adding triamcinolone acetonide liquid mix homogeneously by 2:1 (volume ratio) in high concentration growth factor serum liquid, outer wiping wound surface, wound surface sterilization in every 3 days is changed dressings once.This method repeats once in every 3 months, and did 5 times altogether, effect reaches more than 90%.
3, shut out so-and-so, female, 39 years old, after natural labor 1 tire 15 years go to a doctor.
The first visit time: in November, 2012
Patient's readme: abdominal pregnancy stricture of vagina is obvious, time have the diseases such as pruritus, affect attractive in appearance.
Symptom: have a medical check-up and see: irregular striae gravidarum appears in hypogastric region, and color subtracts obviously, every bar striae gravidarum lines diameter about 2.5mm.
Therapeutic scheme: extract patient's self-blood 20ml, add 1:1000 somatomedin (normal saline dilution with 0.9% holds up Ji again), after high speed centrifugation, obtain and be rich in high concentration growth factor serum liquid, inject striae gravidarum mesoderm and hypodermic layer, epidermis is subtracted at the color peeling off striae gravidarum epidermal area with dot matrix laser or surgical blade, after after being rich in and adding triamcinolone acetonide liquid mix homogeneously by 2:1 (volume ratio) in high concentration growth factor serum liquid, outer wiping wound surface, wound surface sterilization in every 3 days is changed dressings once.This method repeats once in every 3 months, and did 5 times altogether, effect reaches more than 75%.
4, Yang, female, 45 years old, after natural labor 20 years go to a doctor, did liposuction cosmetic surgery in beauty and shaping hospital before 10 years.
The first visit time: in November, 2012
Patient's readme: a little striae gravidarum of abdominal part, almost without diseases such as prurituss, abdominal part out-of-flatness (liposuction is caused), softness is not good enough, affects attractive in appearance.
Symptom: have a medical check-up and see: irregular striae gravidarum appears in hypogastric region, and color subtracts obviously, every bar striae gravidarum lines diameter about 2.5mm.
Therapeutic scheme: extract patient's self-blood 20ml, add 1:1000 somatomedin (normal saline dilution with 0.9% holds up Ji again), after high speed centrifugation, obtain and be rich in high concentration growth factor serum liquid, inject striae gravidarum mesoderm and hypodermic layer, epidermis is subtracted at the color peeling off striae gravidarum epidermal area with dot matrix laser or surgical blade, after after being rich in and adding triamcinolone acetonide liquid mix homogeneously by 2:1 (volume ratio) in high concentration growth factor serum liquid, outer wiping wound surface, wound surface sterilization in every 3 days is changed dressings once.This method repeats once in every 3 months, and did 5 times altogether, striae gravidarum effect reaches more than 90%.By radio-frequency (RF) therapy, to improve abdominal part pliability, satisfaction 80%.
5, Wu so-and-so, female, 40 years old, after natural labor 19 years go to a doctor.
The first visit time: in November, 2012
Patient's readme: a little striae gravidarum of abdominal part, almost without diseases such as prurituss, abdominal part out-of-flatness (liposuction is caused), softness is not good enough, affects attractive in appearance.
Symptom: have a medical check-up and see: irregular striae gravidarum appears in hypogastric region, every bar striae gravidarum lines diameter about 3mm.
Therapeutic scheme: extract patient's self-blood 20ml, add 1:1000 somatomedin (normal saline dilution with 0.9% holds up Ji again), after high speed centrifugation, obtain and be rich in high concentration growth factor serum liquid, inject striae gravidarum mesoderm and hypodermic layer, epidermis is subtracted at the color peeling off striae gravidarum epidermal area with dot matrix laser or surgical blade, after after being rich in and adding triamcinolone acetonide liquid mix homogeneously by 2:1 (volume ratio) in high concentration growth factor serum liquid, outer wiping wound surface, wound surface sterilization in every 3 days is changed dressings once.This method repeats once in every 3 months, and did 5 times altogether, striae gravidarum effect reaches more than 90%.
Wrinkle case (medicine of following case institute external application is the medicine of embodiment 12)
1, Cao, female, 59 years old, go to a doctor in JIUYUE, 2011, forehead many places (about 8-9 root size is uneven) wrinkle, site of disease liniment 3 months, further consultation, face was almost without wrinkle, and effective percentage reaches more than 95%.
2, history so-and-so, female, 69 years old, in May, 2012 go to a doctor, face has many places wrinkle to be mainly distributed in the places such as forehead, eye, buccal, and in the further consultation after 3 months of site of disease liniment, there is a little microgroove (2-3 root) at the place of acceptance, and effective percentage reaches 75%.
3, Lee so-and-so, female, 40 years old, in first visit in June, 2012, forehead, the space between the eyebrows (two brows are shown in, i.e. river word stricture of vagina) obviously wrinkle, in the further consultation after 3 months of site of disease liniment, almost without wrinkle, effective percentage reaches more than 95%.
Augmentation rhinoplasty case (medicine of following case institute external application is the medicine of embodiment 11)
1, thank so-and-so, female, 37 years old, go to a doctor in March, 2011, nose subsides (bridge of the nose and the nasion), in the further consultation after 3 months of site of disease liniment, the bridge of the nose and the nasion increase the moon 0.1 centimetre, again accept treatment once, further consultation after 3 months, the bridge of the nose and the nasion increase remaining sum 0.3-0.4 cm, substantially reach the expection of 80%.
2, Lin, female, 32 years old, go to a doctor in May, 2011, nose subsides (bridge of the nose and the nasion), in the further consultation after 3 months of site of disease liniment, the bridge of the nose and the nasion increase the moon 0.15 centimetre, again accept treatment once, further consultation after 3 months, the bridge of the nose and the nasion increase remaining sum 0.4-0.5 cm, substantially reach the expection of 90%.
3, model so-and-so, female, 35 years old, go to a doctor in June, 2011, nose subsides (nasion), in the further consultation after 3 months of site of disease liniment, the nasion increases the moon 0.2 centimetre, again accepts treatment once, further consultation after 3 months, the bridge of the nose and the nasion increase remaining sum 0.25 cm, reach the expection of 85%.
Facial Depression case (medicine of following case institute external application is the medicine of embodiment 11)
1, so-and-so, female of Liu, first visit in March, 2011, pit (on the right of the place of the left side 23 places) is lost after bilateral temple place 5 place's acne, about diameter is 0.2-0.6 cm, and the degree of depth is about 0.1-0.2 cm, in the further consultation after 3 months of site of disease liniment, two-side recess is almost smooth, further consultation again after 3 months, before the moon 3, further consultation is the same, and effective percentage reaches 90%.
2, poplar, female, first visit in 2011, the sun caves in, at site of disease liniment, obvious improvement is seen after 3 months, accept second time and treat further consultation after latter 3 months, recess increases the moon 0.15 centimetre, accepts third time treatment, further consultation after 3 months, recess increases about 0.25 cm, recess be improved significantly, effective percentage reaches more than 80%.
3, Zhao, year in June, 2011 first visit, temple cave in, at site of disease liniment, obvious improvement is seen after 3 months, accept second time and treat further consultation after latter 3 months, recess increases the moon 0.15 centimetre, accepts third time treatment, further consultation after 3 months, recess increases about 0.3 cm, recess be improved significantly, effective percentage reaches more than 90%.
4, so-and-so, female of Korea Spro, first visit in July, 2011, facial nasolabial fold (decree stricture of vagina) dark or relative elsewhere depression, at site of disease liniment, after 3 months, see obvious improvement, about increase 0.15 centimetre, again accept treatment and increase about 0.2 centimetre after 3 months, effective percentage reaches more than 90%.
Although illustrate and describe the present invention with specific embodiment, however it will be appreciated that can to make when not deviating from the spirit and scope of the present invention many other change and amendment.Therefore, this means to comprise all such changes and modifications belonged in the scope of the invention in the following claims.
Claims (10)
1. dispel a medicine for striae gravidarum, it is characterized in that, comprise following composition:
By volume, autoblood 10-30 part, holding up the multiple 1-5 part of Ji, and described in hold up the multiple concentration of Ji to be 7000-35000IU/mL.
2. medicine of dispelling striae gravidarum according to claim 1, is characterized in that, also comprise: by volume, triamcinolone acetonide 1-2 part.
3. medicine of dispelling striae gravidarum according to claim 1, is characterized in that, by volume, autoblood 10-30 part, holding up the multiple 2-3 part of Ji, and described in hold up the multiple concentration of Ji to be 11600-17500IU/mL.
4. medicine of dispelling striae gravidarum according to claim 1, is characterized in that, by volume, autoblood 10-30 part, holding up the multiple 3-5 part of Ji, and described in hold up the multiple concentration of Ji to be 7000-11600IU/mL.
5. medicine of dispelling striae gravidarum according to claim 1, is characterized in that, by volume, autoblood 10-30 part, holding up the multiple 1-2 part of Ji, and described in hold up the multiple concentration of Ji to be 17500-35000IU/mL.
6. the preparation method dispelling the medicine of striae gravidarum according to claim 1, is characterized in that, comprise the following steps:
Steps A: with normal saline by the described solution holding up Ji to dilute 7000-35000IU/mL again, obtains holding up Ji redissolution liquid;
Step B: by described autoblood with described hold up help redissolve liquid and mix, more centrifugal, the red precipitate of removing bottom, obtains medicine.
7. the preparation method dispelling the medicine of striae gravidarum according to claim 6, is characterized in that, in described step B, after the red precipitate of removing bottom, also adds 1-2 part triamcinolone acetonide.
8. the preparation method dispelling the medicine of striae gravidarum according to claim 6, is characterized in that, described centrifugal method is: centrifugal 6-15min under 2100-2300r/min; Preferably, after the red precipitate of the removing bottom in described step B, also comprise: at 20-30 DEG C, constant temperature places 13-17min.
9. the preparation method dispelling the medicine of striae gravidarum according to claim 6, it is characterized in that, the method mixed in described step B is: what in described autoblood, first add 0.4-0.6 times of total amount holds up Ji redissolution liquid, remix, centrifugal, remove the red precipitate of bottom afterwards, then add surplus hold up Ji redissolve liquid.
10. the preparation method dispelling the medicine of striae gravidarum according to claim 6, is characterized in that, by weight percentage, the concentration of normal saline used is 0.85-0.95%.
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| CN201510138263.3A CN104689301A (en) | 2015-03-27 | 2015-03-27 | Medicine for removing striae gravidarum and preparing method for medicine for removing striae gravidarum |
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| CN201510138263.3A Pending CN104689301A (en) | 2015-03-27 | 2015-03-27 | Medicine for removing striae gravidarum and preparing method for medicine for removing striae gravidarum |
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| CN1814279A (en) * | 2005-01-31 | 2006-08-09 | 北京双鹭立生医药科技有限公司 | Regenerated human alkali fiber-cell growth factor gel former and preparing method |
| CN101379182A (en) * | 2005-12-14 | 2009-03-04 | 器官发生有限公司 | Skin care compositions and treatments |
| CN102188362A (en) * | 2011-05-09 | 2011-09-21 | 董萍 | Autologous whole blood homogenate compound for reconstruction of autologous skin epidermis protective screen |
| US20130096064A1 (en) * | 2011-10-07 | 2013-04-18 | Tissue Repair Company | Flowable formulations for tissue repair and regeneration |
| US20140072613A1 (en) * | 2012-09-10 | 2014-03-13 | Cynthia Lander | Compositions and Methods for Treating Cutaneous Scarring |
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| CN1814279A (en) * | 2005-01-31 | 2006-08-09 | 北京双鹭立生医药科技有限公司 | Regenerated human alkali fiber-cell growth factor gel former and preparing method |
| CN101379182A (en) * | 2005-12-14 | 2009-03-04 | 器官发生有限公司 | Skin care compositions and treatments |
| CN102188362A (en) * | 2011-05-09 | 2011-09-21 | 董萍 | Autologous whole blood homogenate compound for reconstruction of autologous skin epidermis protective screen |
| US20130096064A1 (en) * | 2011-10-07 | 2013-04-18 | Tissue Repair Company | Flowable formulations for tissue repair and regeneration |
| CN104254341A (en) * | 2012-04-25 | 2014-12-31 | 日立化成株式会社 | Sustained release carrier for drugs |
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