CN104678115A - Multi-light-path reagent detection device of integrated quantitative sampling reagent adding device detector - Google Patents
Multi-light-path reagent detection device of integrated quantitative sampling reagent adding device detector Download PDFInfo
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- CN104678115A CN104678115A CN201510082659.0A CN201510082659A CN104678115A CN 104678115 A CN104678115 A CN 104678115A CN 201510082659 A CN201510082659 A CN 201510082659A CN 104678115 A CN104678115 A CN 104678115A
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Abstract
The invention discloses a multi-light-path reagent detection device of an integrated quantitative sampling reagent adding device detector. The detection device comprises a detection receiving circuit board, a bracket for holding an integrated quantitative sampling reagent adding device, a driving device for driving the bracket to swing around an axle, a two-dimension code scanner, light-emitting sources, and a lens path and a photoelectric converter D1 matched with the light-emitting sources, wherein the driving device comprises a blending motor; two or more light-emitting sources are arranged; the light-emitting sources, the driving device and the lens path are arranged on a stand; the output shaft of the blending motor is fixedly connected to the bracket; trunnions are arranged on two sides of the bracket; the trunnions are connected to the output shaft of the blending motor; the bracket is located between the light-emitting sources and the lens path; light from the light-emitting sources is transmitted to the input end of the photoelectric converter D1 by virtue of the lens path; and the output end of the photoelectric converter D1 corresponds to the input end of the detection receiving circuit board. The detection device disclosed by the invention has the advantages of being convenient for use and precise in detection, and being capable of achieving multi-light-path detection inside an integrated machine.
Description
Technical field
The present invention relates to multi-pass and detect reagent device, be specially the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector.
Background technology
Present stage, the stage that single machine completes single type test is rested on more to the test of reagent, one machine can not be multiplex, such as to absorbance detection, scattering turbidimetry detection, Immunofluorescence test etc., each detects the different a kind of detector of needs, when testing staff detects sampling reagent, the integrated quantitative sampling reagent adding device that sampling reagent is housed is needed to place in corresponding detector, all very inconvenient when using and carry, waste time and energy; Meanwhile, verification mechanism be there is no to put into sampling reagent, if once occur testing staff misplace detector, not only can cause testing result inaccurate, sampling reagent waste, more serious may cause the irreversible loss of important sampling reagent.In the market, for patent name for " a kind of integrated quantitative sampling reagent adding device " (its patent No. for: described in patent 201010539091.8) filling sampling reagent device, do not have realize carrying out multiple different light paths selection for its interior reagent type and the equipment detected, very big inconvenience is brought to use, in practical operation, each for different reagent, all need to change detector, greatly reduce the efficiency of testing inspection, present stage, often need the operation of multi-step repeatedly, this also increases the probability that reagent goes bad or pollutes.
Summary of the invention
Technical matters to be solved by this invention be to provide a kind of easy to use, detect precisely, the multi-pass agent detection devices for integrated quantitative sampling reagent adding device detector of a tractor serves several purposes.
The present invention adopts following technical scheme:
The multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector, it comprises and detects circuit board for receiving, for placing the bracket of integrated quantitative sampling reagent adding device, the drive unit swung around axle for driven bracket, Quick Response Code scanner, transmitting illuminant, and the lens passage that matches of transmitting illuminant and photoelectric commutator D1; Described drive unit comprises mixing motor; The quantity of described transmitting illuminant is more than or equal to 2, and the quantity of described lens passage is identical with the quantity of transmitting illuminant; Described transmitting illuminant, drive unit and lens passage are all arranged in frame;
The output shaft of described mixing motor is fixedly connected with described bracket, and described bracket both sides are provided with gudgeon, and described gudgeon is connected with the output shaft of mixing motor; The output shaft direction of described mixing motor is consistent with the radiation direction of transmitting illuminant; Described bracket is between transmitting illuminant and lens passage, and the light of described transmitting illuminant reaches the input end of photoelectric commutator D1 through lens passage, and the output termination correspondence of described photoelectric commutator D1 detects the input end of circuit board for receiving; Described integrated quantitative sampling reagent adding device is provided with the Quick Response Code for the tested reagent of unique identification, and described Quick Response Code scanner and integrated quantitative Quick Response Code position on reagent adding device of sampling is corresponding.
Lens are provided with before the scanning lens of described Quick Response Code scanner.The model of described Quick Response Code scanner can make Keyemce two-dimensional code reader R-610.
Described transmitting illuminant is full wavelength light source and/or laser tube, and the detection circuit board for receiving that described full wavelength light source is corresponding is grating receiving sensor, and the detection circuit board for receiving that described laser tube is corresponding is that adjustable gain light intensity signal receives amplifying circuit;
Described adjustable gain light intensity signal receives amplifying circuit and comprises operation amplifier chip IC 1, digital regulation resistance chip IC 2, feedback resistance R1 ~ R2, electric capacity C1 ~ C6; Described photoelectric commutator D1 is connected between 2 pin of operation amplifier chip IC 1 and ground; Be connected between 2 pin of operation amplifier chip IC 1 and 6 pin of digital regulation resistance chip IC 2 after described resistance R1 and electric capacity C3 parallel connection; Be connected between 4 pin of operation amplifier chip IC and ground after described electric capacity C1 and C2 parallel connection; 6 pin of described operation amplifier chip IC 1 and 7 pin are corresponding 7 pin and the power vd D connecing digital regulation resistance chip IC 2 respectively; Be connected between 7 pin of operation amplifier chip IC 1 and ground after described electric capacity C4 and C5 parallel connection; Described electric capacity C6 is connected in parallel between 8 pin of digital regulation resistance chip IC 2 and ground, and 8 pin of described digital regulation resistance chip IC 2 meet power supply VCC; 5 pin of described digital regulation resistance chip IC 2 are through resistance R2 ground connection; 1,2,3 pin of described digital regulation resistance chip IC 2 connect MCU control pin respectively; The model of described operation amplifier chip IC 1 is OTA121, and the model of described digital regulation resistance chip IC 2 is MCT41050.
Further, described full wavelength light source can be bulb.
When described lens passage is three, one of them needs corresponding laser tube, when two other needs corresponding full wavelength light source, transmitting illuminant is a laser tube and a full wavelength light source, two lens passages share a full wavelength light source, wherein full wavelength light source is placed in lampshade, is located to luminous by the fiber optic conduction light be connected on lampshade.
As a further improvement on the present invention, also comprise for determining that bracket swings the magnet put in place, described magnet is installed on bracket, for identifying that the magnetic inductor of magnet positions is arranged on swing and puts in place place, for identifying that each magnetic inductor of magnet positions is installed on swing and puts in place place, the described swing place of putting in place is each transmitting illuminant place corresponding on the arc track that swings along bracket.
The described magnetic inductor for identifying magnet positions is Hall element.
As a further improvement on the present invention, described frame is adjustable for height support.
Described bracket is the upper and lower open-ended tubular housing that side is provided with vertical opening, and described tubular housing is provided with the light hole of through cavity; The position of described light hole and transmitting illuminant and lens passage in the same horizontal line, and the direction of described light hole and the light of transmitting illuminant corresponding.
The invention has the beneficial effects as follows:
The present invention is rational in infrastructure, easy to use, a tractor serves several purposes can be realized, relevant position is turned to by motor driven bracket, aim at corresponding lens passage, because in integrated quantitative sampling reagent adding device, different sampling reagent needs to adopt different light paths to detect, the present invention can, when not changing instrument, realize automatically detecting in same body difference sampling reagent.
The information on the two-dimension code label on integrated quantitative sampling reagent adding device is positioned at according to the scanning of Quick Response Code scanner, required type of detection can be judged, automatic rotation is matched to respective lens passage and completes detection, and according to the information in Quick Response Code, different determination methods is taked to the signal by detecting circuit board for receiving, by integral for multi-pass reagent detected set, reduce cost, improve efficiency, save the time of testing staff and patient, avoid personal error simultaneously, also can according to 2 D code information by the testing result of patient classification process, for follow-up work is provided convenience.
In addition, before the scanning lens of described Quick Response Code scanner, be provided with lens, regulate the focal length of Quick Response Code scanner as required, easy to use, and shorten the spacing of Quick Response Code scanner and sampling thief, be conducive to the volume reducing integral device, improve over all Integration degree.
Bracket is provided with the magnet for identifying swing position, is conducive to accurate location, improves the accuracy of carriage turns.
Bracket design is the upper and lower open-ended tubular housing that side is provided with vertical opening, and the device contributing to subsequent design moves up and down along this strip-shaped vertical opening, by the sampling thief delivery in bracket to assigned address, practical, easy to use.
Be provided with the frame for fixed transmission light source, drive unit and lens passage in this device, to the equipment that it is installed, there is damping effect, and above-mentioned bracket height be adjustable, each component height level of convenient calibration.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention.
Fig. 2 is the structural representation after the present invention removes drive unit.
Fig. 3 is the position relationship schematic diagram of transmitting illuminant of the present invention and lens passage.
Fig. 4 is the structural representation of bracket in the present invention.
Fig. 5 is the circuit theory diagrams detecting circuit board for receiving embodiment in the present invention.
Fig. 6 is integral type quantitative sampling reagent adding device detector one-piece construction schematic diagram.
Fig. 7 is the structural representation that the present invention mixes structure.
Fig. 8 is the structural representation of fixed head of the present invention.
The structural representation of Fig. 9 fixed head positioning component of the present invention.
Figure 10 is notch of the present invention and protruding continuous action relation schematic diagram.
Figure 11 is the annexation schematic diagram pressing down tooth bar and horizontal carriage of the present invention.
Figure 12 is the structural representation of hatch door plate of the present invention.
Figure 13 is the view that in the present invention, bracket swings to a certain station place.
Wherein, 1 lens, 2 mixing motors, 3 output shafts, 4 transmitting illuminants, 5 lens passages, 6 detect circuit board for receiving, 7 Quick Response Code scanners, 8 light holes, 9 frames, 10 gudgeons, 11 vertical openings, 12 integrated quantitative sampling reagent adding devices, 13 magnets, 14 ajutages, 15 heating plates, 16 detector housings, 17 drive motor, 18 driven wheels, 19 optical fiber, 20 full wavelength light sources, 21 lampshades, 22 grating receiving sensors, 23 trigger switches, 1-3 display, 1-5 fixed orifice, 1-6 splashproof groove, 2-1 presses down tooth bar, 2-4 guide rod, 2-6 guide rail for subsequent use, 2-7 horizontal carriage, 2-8 guide rail, 2-9 presses down linked gear, 2-10 presses down follower gear, 2-11 notch, 2-13 directive slide track, 2-15 hypodontia, 2-16 is protruding, 2-17 locator card, 2-18 pressing plate, 2-19 engaging tooth, 2-21 is from driven wheel, 2-22 shoulder hole, 3-2 bracket, 3-3 screens reed, 3-4 bracing frame, 3-8 fixed head, 3-9 positioning boss, 3-10 locating groove, 3-11 lifter rack frame, 3-12 lifter rack, 3-13 locates snap fit, 3-15 spacing preiection, 3-18 ridge is protruding, 3-21 departs from hypodontia, 4-1 hatch door, 4-2 hatch door plate, 4-3 hatch door post, 4-4 hatch door draw-in groove, 4-5 end-stopping plate, 5-2 presses lobe, 5-3 return spring, 5-4 follower gear, 5-5 upright slide rail, 5-9 pallet, 9-3 guiding arc plate.
Embodiment
Below in conjunction with accompanying drawing 1 ~ 13 and embodiment, the present invention is described in further detail.
Bracket 3-2 in the present embodiment can be called with Chinese patent name " a kind of integrated quantitative sampling reagent adding device " (patent No. is: the device 201010539091.8) recorded with the use of.
The multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector, it comprises and detects circuit board for receiving 6, for placing the bracket 3-2 of integrated quantitative sampling reagent adding device 12, drive unit, Quick Response Code scanner 7, transmitting illuminant 4, the lens passage 5 matched with transmitting illuminant 4 and photoelectric commutator D1; Described drive unit comprises mixing motor 2; The quantity of described transmitting illuminant 4 is more than or equal to 2, and the quantity of described lens passage 5 is identical with the quantity of transmitting illuminant 4; The output shaft 3 of described mixing motor 2 is fixedly connected with described bracket 3-2, and output shaft 3 direction of described mixing motor 2 is consistent with the radiation direction of transmitting illuminant 4; Described bracket 3-2 is between transmitting illuminant 4 and lens passage 5, and the light of described transmitting illuminant 4 reaches the input end of photoelectric commutator D1 through lens passage 5, and the output termination correspondence of described photoelectric commutator D1 detects the input end of circuit board for receiving 6; Described integrated quantitative sampling reagent adding device 12 posts the Quick Response Code for unique identification fluid to be measured, described Quick Response Code scanner 7 and integrated quantitative Quick Response Code position on reagent adding device 12 of sampling is corresponding.
As shown in Figure 4, described bracket 3-2 is the upper and lower open-ended tubular housing that side is provided with strip-shaped vertical opening 11, and described tubular housing is provided with the light hole 8 of through cavity; In the same horizontal line, and the direction of described light hole 8 is corresponding with the light of transmitting illuminant 4 for the position of described light hole 8 and transmitting illuminant 4 and lens passage 5.
Lens are provided with before the scanning lens of described Quick Response Code scanner 7.
Described transmitting illuminant 4 is full wavelength light source 20 and/or laser tube, and the detection circuit board for receiving 6 of described full wavelength light source 20 correspondence is grating receiving sensor 22, and the detection circuit board for receiving 6 that described laser tube is corresponding is adjustable gain light intensity signal reception amplifying circuit;
Described detection circuit board for receiving 6 is adjustable gain light intensity signal reception amplifying circuit, as prior art.
As shown in Figure 5, described adjustable gain light intensity signal reception amplifying circuit comprises operation amplifier chip IC 1, digital regulation resistance chip IC 2, feedback resistance R1 ~ R2, electric capacity C1 ~ C6; Described photoelectric commutator D1 is connected between 2 pin of operation amplifier chip IC 1 and ground; Be connected between 2 pin of operation amplifier chip IC 1 and 6 pin of digital regulation resistance chip IC 2 after described resistance R1 and electric capacity C3 parallel connection; Be connected between 4 pin of operation amplifier chip IC 1 and ground after described electric capacity C1 and C2 parallel connection; 6 pin of described operation amplifier chip IC 1 and 7 pin are corresponding 7 pin and the power vd D connecing digital regulation resistance chip IC 2 respectively; Be connected between 7 pin of operation amplifier chip IC 1 and ground after described electric capacity C4 and C5 parallel connection; Described electric capacity C6 is connected in parallel between 8 pin of digital regulation resistance chip IC 2 and ground, and 8 pin of described digital regulation resistance chip IC 2 meet power supply VCC; 5 pin of described digital regulation resistance chip IC 2 are through resistance R2 ground connection; 1,2,3 pin of described digital regulation resistance chip IC 2 connect MCU control pin respectively; The model of described operation amplifier chip IC 1 is OTA121, and the model of described digital regulation resistance chip IC 2 is MCT41050.
Further, described full wavelength light source 20 can be bulb.
As a further improvement on the present invention, also comprise for determining that bracket 3-2 swings the magnet 13 put in place, described magnet 13 is installed on bracket 3-2, for identifying that the magnetic inductor of magnet 13 position is arranged on swing and puts in place place, described for identifying that the magnetic inductor of magnet 13 position is Hall element.
As a further improvement on the present invention, frame 9 comprises the transmitting illuminant support for fixed transmission light source 4, the drive unit support for fixed drive device and/or the lens channel bracket for fixed lens passage 5.This three can have, and also can selectivity install, mainly for by light path adjustment point-blank.
As a further improvement on the present invention, described frame 9 is adjustable for height support.
As shown in Figure 3, when described lens passage 5 is three, one of them needs corresponding laser tube, when two other needs corresponding full wavelength light source 20, transmitting illuminant 4 is a laser tube and a full wavelength light source 20, two lens passages 5 share a full wavelength light source 20, and wherein full wavelength light source 20 is placed in lampshade 21, are located to luminous by optical fiber 19 conducting light be connected on lampshade 21.As Fig. 1 ~ 3 and Figure 13 shows that mixing motor 2 output shaft 3 drive bracket 3-2 to turn to the schematic diagram of respective lens passage 5 position, three lens passages, 5, three the lens passages 5 devising three transmitting illuminants 4 and correspondence in the present embodiment are absorbance detection passage, scattering turbidimetry passage and immunofluorescence passage respectively; Absorbance detection passage adopts optical fiber light-guiding technology that light intensity is conducted to grating module; Scattering turbidimetry passage, light is received by three lens device D1 that is photoelectrically converted; Immunofluorescence passage, light is after optical filter filters, and the device D1 that is photoelectrically converted receives.Described detection circuit board for receiving 6 is adjustable gain light intensity signal reception amplifying circuit; Described detection circuit board for receiving 6, according to the difference of corresponding transmitting illuminant 4, can make the circuit with similar function of current amplification circuit or integrating amplification circuit or other correspondences, belong to the circuit that those skilled in the art are general, state no longer to the greatest extent herein.
In the present embodiment, all current amplification circuit is connect through photoelectric commutator D1 after described absorbance detection passage and scattering turbidimetry passage, as shown in Figure 5, described current amplification circuit is that adjustable gain light intensity signal receives amplifying circuit, namely comprises operation amplifier chip IC 1, digital regulation resistance chip IC 2, feedback resistance R1 ~ R2, electric capacity C1 ~ C6; Described photoelectric commutator D1 is connected between 2 pin of operation amplifier chip IC 1 and ground; Be connected between 2 pin of operation amplifier chip IC 1 and 6 pin of digital regulation resistance chip IC 2 after described resistance R1 and electric capacity C3 parallel connection; Be connected between 4 pin of operation amplifier chip IC 1 and ground after described electric capacity C1 and C2 parallel connection; 6 pin of described operation amplifier chip IC 1 and 7 pin are corresponding 7 pin and the power vd D connecing digital regulation resistance chip IC 2 respectively; Be connected between 7 pin of operation amplifier chip IC 1 and ground after described electric capacity C4 and C5 parallel connection; Described electric capacity C6 is connected in parallel between 8 pin of digital regulation resistance chip IC 2 and ground, and 8 pin of described digital regulation resistance chip IC 2 meet power supply VCC; 5 pin of described digital regulation resistance chip IC 2 are through resistance R2 ground connection; 1,2,3 pin of described digital regulation resistance chip IC 2 connect MCU control pin respectively; The model of described operation amplifier chip IC 1 is OTA121, and the model of described digital regulation resistance chip IC 2 is MCT41050.Connect integrating amplification circuit through photoelectric commutator D1 after described immunofluorescence passage, described integrating amplification circuit is announce in the patent of ZL200820077266.6 in the patent No..
The course of work of the present invention is as follows:
First, the integrated quantitative sampling reagent adding device 12 that sampling reagent is housed is put into bracket 3-2, according to the different tested reagent held in integrated quantitative sampling reagent adding device 12, manual control drive motor 17 rotates, thus drive the sampling of the integrated quantitative in bracket 3-2 reagent adding device 12 to swing to corresponding lens passage 5 place, select corresponding light signal receiving detection device, namely selecting in the present embodiment is absorbance detection passage, scattering turbidimetry passage or immunofluorescence passage, after determining passage, automatic startup mixing motor 2, the output shaft 3 of mixing motor 2 rotarily drives bracket 3-2 and rotates to an angle, make the light hole 8 on transmitting illuminant 4 aligning bracket 3-2, at each transmitting illuminant 4 place or its opposite, magnetic inductor is installed, when the magnet 13 sensed on bracket 3-2 puts in place, because each lens passage 5 has corresponding transmitting illuminant 4, the emission of light that will start transmitting illuminant 4 penetrates the sampling reagent in integrated quantitative sampling reagent adding device 12, its light coaxially runs through with corresponding lens passage 5 through over-sampling reagent, light intensity signal will be received through photoelectric commutator D1 and convert electric signal to, this electric signal is sent to and detects circuit board for receiving 6, size according to light intensity signal produces corresponding electric current, electric current is via operation amplifier chip IC 1, R1, C3, digital regulation resistance chip IC 2, the amplifying circuit of R2 composition amplifies and is converted to the 6 pin outputs of voltage signal by IC1, described digital regulation resistance chip IC 2 is tunable digital potentiometer, it acts in the feedback circuit of amplifying circuit, the enlargement factor of circuit is changed to reach the function of adjustment gain by the tap position of MCU control signal adjustment digital regulation resistance chip IC 2, testing result is obtained after process, the course of work is simple and convenient, accuracy is high.
When posting two-dimension code label on the integrated quantitative sampling reagent adding device 12 of this device, need to arrange Quick Response Code scanner 7 in this device, described two-dimension code label aimed at by Quick Response Code scanner 7, after Quick Response Code scanner 7 scans, read institute's information, determine lens passage 5 type that will select accordingly, subsequent process is the same.
Also temperature regulating device is provided with in this detector, described temperature regulating device comprises radiating block and is arranged on radiator fan, heating plate 15 and the temperature sensor on radiating block, described radiator fan is arranged on radiating block side, described heating plate 15 contacts with radiating block, and described temperature sensor is arranged on radiating block or in detector housing.Described radiating block is also provided with ajutage 14, and described ajutage 14 is socketed on radiating block.
As shown in accompanying drawing 1 ~ 13, the course of work of whole detection instrument is as follows:
First be the start detection of the detector for integrated quantitative sampling reagent adding device 12:
After this detector switches on power, temperature sensor work, obtains real time temperature in cabin, and when temperature is equal to or higher than default minimum setting examination criteria temperature, temperature regulating device enters holding state; When temperature is lower than when presetting minimum setting examination criteria temperature, temperature regulating device work, after energising, heating plate 15 works, and improves the temperature of detector housing 16 inside, when temperature be equal to or higher than preset the highest numerical value time heating plate 15 quit work; Temperature sensor guarantees that detector housing 16 internal temperature is not less than preset temperature range.
Be designed with the sniffer of integrated quantitative sampling reagent adding device 12, integrated quantitative sampling reagent adding device 12 whether has been put into for detecting in bracket 3-2, if drawn integrated quantitative sampling reagent adding device 12 after receiving the feedback signal of described sniffer, so alarm, starts the flow process preparing to enter follow-up mixing, detection; When the signal not having integrated quantitative sampling reagent adding device 12 to put into, this detector enters holding state.Described sniffer can be trigger switch 23 or other inductors, such as infrared sensing switch or proximity switch.
When needs detect reagent in integrated quantitative sampling reagent adding device 12, drive motor 17 in body starts, driven wheel 18 drives and presses down from driven wheel 2-10 with from driven wheel 2-21 action, pressing down linked gear 2-9 from driven wheel 2-10 drive pushes to away from driven wheel 18 by protruding 2-16 by horizontal carriage 2-7, the hatch door plate 4-2 of body upper end is pushed aside by hatch door draw-in groove 4-4 by the hatch door post 4-3 on horizontal carriage 2-7 top, open the hatch door 4-1 above detector housing 16, meanwhile, from the lifter rack 3-12 lifting that driven wheel 2-21 will engage with it, lifter rack frame 3-11 increases precalculated position, in now integrated quantitative sampling reagent adding device 12, the pallet 5-9 of reagent rises to most significant digit, now this detector waits for putting in place of integrated quantitative sampling reagent adding device 12.
Next is that Reagent Tube information reads:
Integrated quantitative to be detected sampling reagent adding device 12 is put into by hatch door 4-1 by operating personnel, described detector housing 16 times Founders are provided with guiding arc plate 9-3 to hatch door 4-1 place, reagent adding device 12 of being sampled by integrated quantitative under the guiding of described guiding arc plate 9-3 is inserted in above-mentioned bracket 3-2, integrated quantitative sampling reagent adding device 12 is printed with information code, described information code and information read device are just right, after integrated quantitative sampling reagent adding device 12 puts in place, described sniffer senses, then judge that integrated quantitative sampling reagent adding device 12 puts in place, Quick Response Code scanner 7 reads the information code on integrated quantitative sampling reagent adding device 12, according to the transmitting illuminant 4 that the information in information code judges the angle that mixing motor 2 should rotate and should enable, which kind of namely judge to select bracket 3-2 to rotate corresponding transmitting illuminant 4 according to the detected types of agents information that information code represents, namely which kind of selects detect light path.
Information code on integrated quantitative sampling reagent adding device 12 can be bar code, and also can be Quick Response Code, corresponding information read device be apparatus for reading of bar code or Quick Response Code scanner 7.
Next be the fixing of integrated quantitative sampling reagent adding device 12:
After information reads, drive motor 17 startup rotates backward and drives driven wheel 18 to move, driven wheel 18 drives and presses down from driven wheel 2-10 with from driven wheel 2-21 action, drive from driven wheel 2-10 and press down linked gear 2-9, and press down this mode in notch 2-11 that linked gear 2-9 and the protruding 2-16 pressed down on follower gear 2-10 be plugged on horizontal carriage 2-7 horizontal component by being arranged on, horizontal carriage 2-7 is stirred near driven wheel 18, horizontal carriage 2-7 top is provided with hatch door post 4-3, the hatch door plate 4-2 that body upper end is used for covering hatch door 4-1 by hatch door draw-in groove 4-4 by described hatch door post 4-3 reverses, close the hatch door 4-1 above body, detector inside is made to form dark situation, the pressing plate 2-18 being arranged on horizontal carriage 2-7 upper end also moves to directly over integrated quantitative sampling reagent adding device 12 thereupon, close from driven wheel 2-21 at horizontal carriage 2-7, simultaneously, be fixed on and horizontal carriage 2-7 presses down tooth bar 2-1 to pressing down follower gear 2-10 and to press down linked gear 2-9 close, and press down engaging tooth 2-19 on tooth bar 2-1 respectively with follower gear 2-10 with press down linked gear 2-9 and engage,
Meanwhile, from driven wheel 2-21 also reverse rotation, the lifter rack 3-12 engaged with it declines, drive lifter rack frame 3-11 to decline thereupon, the pallet 5-9 lifting integrated quantitative sampling reagent adding device 12 also declines, therefore integrated quantitative sampling reagent adding device 12 declines with pallet 5-9 by self gravitation under the constraint of bracket 3-2, integrated quantitative sampling reagent adding device 12 entirety enters in bracket 3-2, when the integrated quantitative sampling flange of reagent adding device 12 and screens reed 3-3 conflict, integrated quantitative reagent adding device 12 of sampling no longer declines with pallet 5-9, now the chute of bracket 3-2 in lifter rack frame 3-11 side is corresponding with the spacing preiection 3-15 position on lifter rack frame 3-11, suitable in order to ensure that the position of chute and spacing preiection 3-15 matches, in the locating groove 3-10 of now ridge snap fit head 3-20 holding positioning boss 3-9 on fixed head 3-8 of the location snap fit 3-13 of lifter rack frame 3-11, bracket 3-2 now drives gliding groove can swing along spacing preiection 3-15 at mixing motor 2, working position is now mixing position.In mixing position, mixing motor 2 drives bracket 3-2 to swing, and the chute spacing preiection 3-15 arcuately of arc slides, and spacing preiection 3-15 can be interrupted setting.
Now, the track that described bracket 3-2 swings is corresponding with the radian of the spacing preiection 3-15 on lifter rack frame 3-11, suitable in order to ensure that track that bracket 10 swings and the radian of spacing preiection 3-15 match mutually, in the locating groove 3-10 of now ridge snap fit head 3-20 holding positioning boss 3-9 on fixed head 3-8 of the location snap fit 3-13 of lifter rack frame 3-11, bracket 10 now can swing along the radian of spacing preiection 3-15 under the driving of mixing motor 3-1, and working position is now mixing position.
In mixing position, mixing motor 3-1 drives bracket 10 to swing, and bracket 10 spacing preiection 3-15 arcuately slides, and spacing preiection 3-15 can be interrupted setting.
Described mixing motor 2 continues to rotate backward drive driven wheel 18 and moves, be separated from driven wheel 2-21 with lifter rack 3-12, lifter rack frame 3-11 moves down, spacing preiection 3-15 moves down thereupon and misplaces with chute, and discontinuous spacing preiection 3-15 is stuck in card holder 3-2 both sides and is used for fixing bracket 3-2; Working position is now depressed position.
Although be separated from driven wheel 2-21 with lifter rack 3-12, but can lifter rack frame 3-11 pressure be put at lowest order from the pressure lobe 5-2 on driven wheel 2-21 top, now, with press down linked gear 2-9 and press down that follower gear 2-10 engages press down tooth bar 2-1 dynamic pressure plate 2-18 can be with to move down, sample integrated quantitative the flange press-in screens reed 3-3 of reagent adding device 12, the formula that is fixed as one quantitative sampling reagent adding device 12.
In depressed position, described bracket 3-2 and integrated quantitative sampling reagent adding device 12 are fixed, described pressing plate 2-18 is applying pressure to integrated quantitative sampling reagent adding device 15, and described screens reed 3-3 is used for misplacing when preventing integrated quantitative sampling reagent adding device 15 pressurized.
Described follower gear 5-4 and/or driven wheel 2-21 is provided with pressure lobe 5-2, described pressure lobe 5-2 one end is corresponding with lifter rack 3-12 top.When pressing lobe 5-2 to be arranged on follower gear 5-4, be hinged in the middle part of described pressure lobe 5-2 with follower gear 5-4, the other end is connected with follower gear 5-4 by return spring 5-3.When pressing lobe 5-2 to be arranged on from driven wheel 2-21 in like manner.Because pressure lobe 5-2 makes pressing plate 2-18 press down under the drive of driven wheel 16, the follower gear 2-21 now engaged and lifter rack 3-12 can hinder pressing plate 2-18 to press down, when therefore pressing down, follower gear 2-21 and lifter rack 3-12 must depart from, lifter rack frame 3-11 after disengaging is not restricted, and therefore arranging pressure lobe 5-2 will press all the time and put in bottom by lifter rack frame 3-11 freely.
Symmetrically arranged follower gear 5-4 can be fixedly connected with by connecting rod with from driven wheel 2-21, increases the stability of follower gear 5-4.
Then be blending process:
After integrated quantitative sampling reagent adding device 12 clicks into place, drive motor 17 starts makes body get back to mixing position, mixing motor 2 starts makes bracket 3-2 swing, first time mixing is carried out to integrated quantitative sampling reagent adding device 12, the blood sample of reagent and collection is mixed, first time mixing time (number of times) arrives the startup of setting-up time (number of times) rear drive motor 17 makes body turn back to depressed position, pressing plate 2-18 second time presses integrated quantitative sampling reagent adding device 12, the reservoir film storing detection agent is pierced through, a small amount of air is made to enter reservoir, now detect liquid not excessive, drive motor 17 starts makes body return mixing position, motor 2 again starts and carries out second time mixing, second time mixing time (number of times) arrives the startup of setting-up time (number of times) rear drive motor 17 makes body turn back to depressed position, pressing plate 2-18 third time presses Reagent Tube, detection agent is all extruded, body gets back to mixing position again, carry out third time mixing, third time mixing time (number of times) arrives setting-up time (number of times) mixing and terminates.When depression repeatedly, horizontal carriage 2-7 moves forward and backward repeatedly, and now hatch door post 4-3 is free to slide in hatch door draw-in groove 4-4, and hatch door plate 4-2 is unaffected.
Further improvement is, next be that integrated quantitative is sampled in reagent adding device 12 fixation procedure and blending process, radial magnetizing magnet is fixedly installed from one end of the rotation axis of driven wheel 2-21, frame 9 is provided with the magnetometric sensor corresponding with radial magnetizing magnet, is controlled by the stopping of information to drive motor 17 of magnetometric sensor.
Or be modified into, the oscillation end of described bracket 3-2 is provided with magnet 13, for identifying that the magnetic inductor of magnet 13 position is arranged on swing and puts in place place, for identifying that each magnetic inductor of magnet 13 position is installed on swing and puts in place place, the described swing place of putting in place is along each transmitting illuminant 4 place corresponding on the arc track of bracket 3-2 swing, in a word need bracket 3-2 drive the integrated quantitative in it sample reagent adding device 12 swing to where stop, just wherein magnetic inductor is installed, make bracket 3-2 swing to magnetic inductor induction on position time, give mixing motor 2 one signals, stop operating and lock this position, guarantee that the light hole 8 on bracket 3-2 this moment aims at transmitting illuminant 4, what the opposite side of light hole 8 was aimed at is corresponding lens passage 5, form unimpeded light path, prepare for light path detects.
Described fixed head 3-8 is provided with positioning boss 3-9, described positioning boss 3-9 is placed in the slot to make way of lifter rack frame 3-11, described positioning boss 3-9 both sides are provided with locating groove 3-10, in described slot to make way, two side is provided with the location snap fit 3-13 suitable with locating groove 3-10, and described locating groove 3-10 is between the protruding 3-18 of two adjacent ridges.
Described horizontal carriage 2-7 is door type structure, described horizontal carriage 2-7 is provided with and presses down rack frame 2-1; The described rack frame 2-1 that presses down is frame-type structure, is provided with pressing plate 2-18 at an upper portion thereof, described in press down rack frame 2-1 side and be provided with engaging tooth 2-19, its opposite side is provided with the directive slide track 2-13 for leading; The side of described horizontal carriage 2-7 is provided with the convex edge of matching with described directive slide track 2-13, and make to press down rack frame 2-1 and directive slide track 2-13 can be relied on to move up and down along horizontal carriage 2-7, the bottom of described horizontal carriage 2-7 is frame 9.
Next be testing process:
Integrated quantitative sampling reagent adding device 12 after having mixed gets back to the vertical position before mixing, this time transmitting illuminant 4 of inspection sends detection light, circuit board for receiving 6 is detected through arriving after reagent to be detected, optical information is converted to electric signal and is back to signal processing circuit by detection circuit board for receiving 6, analysis result is delivered to control module by signal processing circuit, and control module is delivered to display 1-3, wireless transmitter module and printer by after testing result and the Reagent Tube information integration that stores for future use.
Finally that drive motor 17 rotates backward, open body hatch door 4-1, reagent adding device 12 of being sampled by integrated quantitative sends back to deliver from vault position, deliver from vault position is that pallet 5-9 reagent adding device 12 of being sampled by integrated quantitative is lifted to extreme higher position, instrument provides the prompting of test ending, operating personnel take integrated quantitative sampling reagent adding device 12 away, and control module detects in instrument does not have integrated quantitative sampling reagent adding device 12, and holding state got back to by instrument.
The present invention identifies multi-pass agent detection devices automatically in order to protect, and other explanations are to embody its working method and process, do not belong to protection content of the present invention.
Above embodiment only in order to technical scheme of the present invention to be described, is not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in previous embodiment, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of embodiment of the present invention technical scheme.
Claims (10)
1. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector, is characterized in that: it comprises bracket (3-2) for placing integrated quantitative sampling reagent adding device (12), the drive unit that swings around axle for driven bracket (3-2), transmitting illuminant (4) and the light signal receiving detection device that matches with transmitting illuminant (4); The quantity of described transmitting illuminant (4) is more than or equal to 2, and described transmitting illuminant (4) and corresponding light signal receiving detection device lay respectively at the both sides of described bracket (3-2) swinging plane.
2. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 1, it is characterized in that: it also comprises Quick Response Code scanner (7), described integrated quantitative sampling reagent adding device (12) is provided with the Quick Response Code for the tested reagent of unique identification, and described Quick Response Code scanner (7) and integrated quantitative are sampled, and above Quick Response Code position is corresponding for reagent adding device (12).
3. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 1 and 2, it is characterized in that: described light signal receiving detection device comprises photoelectric commutator D1 and detects circuit board for receiving (6), lens passage (5) is provided with between described transmitting illuminant (4) and photoelectric commutator D1, the reagent of light successively in integrated quantitative sampling reagent adding device (12) of described transmitting illuminant (4), lens passage (5) reaches the input end of photoelectric commutator D1, the output termination correspondence of described photoelectric commutator D1 detects the input end of circuit board for receiving (6).
4. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 1 and 2, is characterized in that: described drive unit comprises mixing motor (2); The output shaft (3) of described mixing motor (2) is fixedly connected with described bracket (3-2), and output shaft (3) direction of described mixing motor (2) is consistent with the radiation direction of transmitting illuminant (4); Described bracket (3-2) is positioned between transmitting illuminant (4) and corresponding light signal receiving detection device.
5. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 3, is characterized in that: described detection circuit board for receiving (6) is adjustable gain light intensity signal reception amplifying circuit.
6. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 5, is characterized in that: described adjustable gain light intensity signal receives amplifying circuit and comprises operation amplifier chip IC 1, digital regulation resistance chip IC 2, feedback resistance R1 ~ R2, electric capacity C1 ~ C6; Described photoelectric commutator D1 is connected between 2 pin of operation amplifier chip IC 1 and ground; Be connected between 2 pin of operation amplifier chip IC 1 and 6 pin of digital regulation resistance chip IC 2 after described resistance R1 and electric capacity C3 parallel connection; Be connected between 4 pin of operation amplifier chip IC 1 and ground after described electric capacity C1 and C2 parallel connection; 6 pin of described operation amplifier chip IC 1 and 7 pin are corresponding 7 pin and the power vd D connecing digital regulation resistance chip IC 2 respectively; Be connected between 7 pin of operation amplifier chip IC 1 and ground after described electric capacity C4 and C5 parallel connection; Described electric capacity C6 is connected in parallel between 8 pin of digital regulation resistance chip IC 2 and ground, and 8 pin of described digital regulation resistance chip IC 2 meet power supply VCC; 5 pin of described digital regulation resistance chip IC 2 are through resistance R2 ground connection; 1,2,3 pin of described digital regulation resistance chip IC 2 connect MCU control pin respectively; The model of described operation amplifier chip IC 1 is OTA121, and the model of described digital regulation resistance chip IC 2 is MCT41050.
7. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 1 and 2, it is characterized in that: it also comprises for determining that bracket (3-2) swings the magnet (13) put in place, described magnet (13) is installed on bracket (3-2), for identifying that each magnetic inductor of magnet (13) position is installed on swing and puts in place place, the described swing place of putting in place is each transmitting illuminant (4) place corresponding on the arc track that swings along bracket (3-2).
8. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 7, is characterized in that: for identifying that the magnetic inductor of described magnet (13) position is Hall element.
9. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 1 and 2, it is characterized in that: described bracket (3-2) is provided with the tubular housing of vertical opening (11) for side, and described tubular housing is provided with the light hole (8) of through cavity; The position of described light hole (8) is corresponding with transmitting illuminant (4).
10. the multi-pass agent detection devices of integrated quantitative sampling reagent adding device detector according to claim 2, is characterized in that: be provided with lens (1) before the scanning lens of described Quick Response Code scanner (7).
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| CN109377844A (en) * | 2018-12-29 | 2019-02-22 | 庞博 | A kind of physical lens experimental provision being conveniently replaceable adjusting |
| WO2020155314A1 (en) * | 2019-02-01 | 2020-08-06 | 深圳市金准生物医学工程有限公司 | Optical sampling module having balanced sampling width and precision, and immunofluorescence assay equipment |
| CN111721763A (en) * | 2020-07-28 | 2020-09-29 | 杭州启创生物技术有限公司 | Multipurpose rapid detection device |
| WO2022078132A1 (en) * | 2020-10-16 | 2022-04-21 | 石家庄禾柏生物技术股份有限公司 | Multi-methodology combined optical path |
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