CN104666792A - Traditional Chinese medicine composition for treating endometrial hyperplasia caused by cold coagulation and blood stasis - Google Patents
Traditional Chinese medicine composition for treating endometrial hyperplasia caused by cold coagulation and blood stasis Download PDFInfo
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- CN104666792A CN104666792A CN201510053921.9A CN201510053921A CN104666792A CN 104666792 A CN104666792 A CN 104666792A CN 201510053921 A CN201510053921 A CN 201510053921A CN 104666792 A CN104666792 A CN 104666792A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating endometrial hyperplasia caused by cold coagulation and blood stasis. The traditional Chinese medicine composition is characterized by being prepared from the following medicinal materials in parts by weight: 15-20 parts of desmodium triflorum, 1-3 parts of asarum wulingense, 1-3 parts of heartleaf saussurea root, 9-12 parts of sida szechuensis, 20-25 parts of christia constricta, 15-20 parts of rubus alceaefolius poir, 6-9 parts of paraquilegia, 12-15 parts of pratia nummularia, 10-20 parts of chelonopsis odontochila diels var.smithii(Kudo)C.Y.Wu,12-15 parts of common euscaphis fruit seeds, 6-10 parts of piper thomsonii, 10-15 parts of rubus pirifolicus smith, 5-10 parts of lethariella zahlbruckneria and 6-12 parts of allium splendens willd. The traditional Chinese medicine composition disclosed by the invention is used for treating endometrial hyperplasia caused by cold coagulation and blood stasis, and is high in effective rate, reliable in curative effect and free of recur after healing.
Description
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine composition being used for the treatment of cold blood stasis type endometrial hyperplasia.
Background technology
Endometrial hyperplasia belongs to " metrorrhagia " category of the traditional Chinese medical science.Its Etiological is that the strongly fragrant resistance of damp-heat in lower-JIAO, congestion, QI and blood are obstructed, and blood circulating out of vessels is excessive.The symptom of endometrial thickness is irregular menses, menostaxis and excessive menstruation.Endometrial hyperplasia has certain cAMP content, therefore is listed in precancerous lesion.Endometrial hyperplasia all has a great impact for the healthy of women and fertility, and therefore Therapeutic Method is also of crucial importance.At present, treat endometrial hyperplasia method to mainly contain: western medical treatment, Chinese traditional treatment, operative treatment.What doctor trained in Western medicine mainly adopted is promoting ovulation drug or hormone medicine, and the induced ovulation that Drug therapy is simple or the endometrial hyperplasia suppressing estrogen to cause, though can improve symptom, cannot remove old complaint; Operative treatment refers generally to dilatation and curettage of uterine or hysterectomy, and dilatation and curettage of uterine can scrape off the inner membrance thickened, and cannot remove focus, though and hysterectomy thoroughly can treat endometrial thickness, but very large to patient's injury, postoperative also would not be conceived; Chinese medicine can be good at the various symptoms eliminating patient, and anti-proliferate, fibrosis and calcification can eliminate again the pathological changes of gynecological's tissue simultaneously, thoroughly remove focus, so can play the effect for the treatment of both the principal and secondary aspects of a disease from root.The endometrial hyperplasia that the traditional Chinese medical science causes according to different reason, carries out Coryza Treated by Syndrome Differentiation in conjunction with clinical practice, is divided into by primary disease: qi stagnation and blood stasis type, cold blood stasis type, Qi deficiency blood stasis type, heat stagnation blood stasis type, kidney deficiency blood stasis type.At present, the Chinese medicine for the treatment of endometrial hyperplasia has multiple, but the Chinese patent medicine being directed to cold blood stasis type endometrial hyperplasia is actually rare, but also there is the defects such as cure rate is lower.
Summary of the invention
Object of the present invention aims to provide a kind of Chinese medicine for the treatment of cold blood stasis type endometrial hyperplasia, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing cold blood stasis type endometrial hyperplasia.
For achieving the above object, the present invention by the following technical solutions: a kind of Chinese medicine for the treatment of cold blood stasis type endometrial hyperplasia, is characterized in that being made up of the medical material of following weight proportion:
3 gold careless 15-20 parts, Herba seu Radix Metaplexis hemsleyanae 1-3 part, Herba Colei Pumili 1-3 part, Herba Sidae Szechuensis 9-12 part, long tube Vespertilio grass 20-25 part, Radix seu Folium Rubi alceaefolii 15-20 part, Folium Paraquilegiae microphyllae 6-9 part, Herba pratiae begonifoliae 12-15 part, the fragrant 10-20 part of cognate bell, Fructus seu semen euscaphis japonicae 12-15 part, carefully Caulis Piperis Boehmeriaefolii 6-10 part, Radix Rubi pirifolii 10-15 part, Alectoria virens Tayl. 5-10 part, brightness Herba Alii fistulosi 6-12 part.
Most preferred embodiment of the present invention strangles 9-12 part, Cortex Trematis Cannabinae Radicis 15-20 part for adding to break by a fall in above-mentioned formula again, to increase the effect of blood circulation promoting and blood stasis dispelling further.
Source and the function of medical material involved in formula cure mainly as follows:
3 gold grass [source] pulse family Desmodium genus plant 3 gold careless Desmodium triflorum (L.) DC., with all herbal medicine.Xia Qiu gathers, and cleans and dries or using fresh herb.[nature and flavor] are bitter, micro-pungent, temperature.[function cures mainly] promoting the circulation of QI to relieve pain, dispelling cold by warming the meridian, removing toxic substances.For heatstroke stomachache, colicky, menoxenia, dysmenorrhea, puerperal arthralgia, rabies.
Herba seu Radix Metaplexis hemsleyanae [source] medical material Ji Yuan: be the root of aristolochiaceae plant Five Ridges Herba Asari, rhizome or herb.[nature and flavor] are pungent; Temperature [return through] lung; Stomach is through [function cures mainly] dispelling cold by warming the meridian; Relieving cough and resolving phlegm; Reducing swelling and alleviating pain.Main stomachache; Cough with asthma; Traumatic injury; Scald; Venom; Toothache is controlled containing coughing.
Herba Colei Pumili [source] medical material Ji Yuan: be the herb of aristolochiaceae plant Herba Colei Pumili and Asarum longerhizomatosum.[nature and flavor] are pungent; Bitter; Temperature; Mild toxicity [return through] lung; Liver; Spleen; Stomach is through [function cures mainly] dispelling cold by warming the meridian; Expelling phlegm for arresting cough; Dissipating blood stasis for subsidence of swelling; Promoting the circulation of QI to relieve pain.Main cough due to wind and cold; Anemofrigid cold; Chronic bronchitis; Asthma; Chronic gastritis; Wind and cold arthralgia pain; Caries pain; Traumatic injury; Venom.
Herba Sidae Szechuensis [source] medical material Ji Yuan: be the branch and leaf of Malvaceae plant Herba Sidae Szechuensis.[nature and flavor] are bitter; Cold [return through] lung; Liver Channel [function cures mainly] stimulating milk secretion; Invigorate blood circulation; Dampness removing; Removing toxic substances.Main agalactia; Acute mastitis; Carbuncle; Urine leaching is puckery; Have loose bowels; Dysentery; Amenorrhea; Injury and bone fracture.
Long tube Vespertilio grass [source] pulse family Vespertilio grass platymiscium long tube Vespertilio grass, is used as medicine with Herb.[nature and flavor] are pungent, cool.[function cures mainly] blood circulation promoting and blood stasis dispelling, removing toxic substances and promoting subsidence of swelling, pain relieving.For traumatic injury congestive edema, rheumatic ostalgia, pulmonary tuberculosis is coughed, snake bite and insect sting, carbuncle skin ulcer etc.
Radix seu Folium Rubi alceaefolii [source] medical material Ji Yuan: be root, the leaf of rosaceous plant Radix seu Folium Rubi alceaefolii.[nature and flavor] are sweet light; Flat [return through] stomach; Liver Channel [function cures mainly] clearing away heat-damp and promoting diuresis, hemostasis, dissipating blood stasis.Main hepatitis, dysentery, enteritis, mastitis, stomatitis, march hemoglobinuria, traumatic hemorrhage, hepatosplenomegaly, traumatic injury, rheumatic ostalgia.
Break by a fall and strangle [source] medical material Ji Yuan: be the leaf of Flacourtiaceae plant longleaf xylosma, thorn and seed.[nature and flavor] bitter in the mouth; Puckery; [function cures mainly] cold in nature clearing away heat-damp and promoting diuresis; Blood circulation promoting and blood stasis dispelling; Reducing swelling and alleviating pain; Lactogenic.Main jaundice; Edema; Traumatic injury; Fracture; Amenorrhea; Carbuncle sore tumefacting virus; Galactostasis; Skin ulcer tinea; Scrofula.
Cortex Trematis Cannabinae Radicis [source] medical material Ji Yuan: be the root bark Herb of Ulmaceae Cortex Trematis Cannabinae Radicis.[nature and flavor] are sweet; Light; Cold nature; [function cures mainly] diuretic; Removing toxic substances; Blood circulation promoting and blood stasis dispelling.Main watery diarrhea; Influenza; Venom; Injured bone.
Folium Paraquilegiae microphyllae [source] medical material Ji Yuan: be leaf or the aerial parts of ranunculaceae plant Folium Paraquilegiae microphyllae.[nature and flavor] bitter in the mouth; Puckery; [return through] cold in nature liver; Kidney; Spleen channel [function cures mainly] blood circulation promoting and blood stasis dispelling; Sore is stopped blooding.Main traumatic injury; Amenorrhea; Dysmenorrhea; Traumatic hemorrhage; Incised wound; Wound disunion of a specified duration; Metrostaxis.
Herba pratiae begonifoliae [source] medical material Ji Yuan: be the herb of Campanulaceae Herba pratiae begonifoliae.[nature and flavor] acrid in the mouth; Bitter; Property flat [function cures mainly] expelling wind and removing dampness; Invigorate blood circulation; Removing toxic substances.Main rheumatalgia; Traumatic injury; Menoxenia; Conjunctival congestion and swelling pain; Acute mastitis; Innominate toxic swelling.
Fragrant [source] medical material Ji Yuan of cognate bell: be the whole herb with root that lip section plant cognate bell is fragrant.[nature and flavor] acrid in the mouth; [function cures mainly] warm in nature dispelling wind; Cold expelling; Dredging collateral.Main anemofrigid cold; Anemofrigid-damp arthralgia.
Fructus seu semen euscaphis japonicae [source] medical material Ji Yuan: be the fruits and seeds of the wild crow Chinese toon of Staphyleaceae plant.[nature and flavor] are pungent; Bitter; Temperature [return through] liver; Stomach; Kidney channel [function cures mainly] expelling wind and cold; Promoting the circulation of QI to relieve pain; Dispersing swelling and dissipating binds.Main stomachache; Colic of cold type pain; Have loose bowels; Dysentery; Proctoptosis; Have through uncomfortable; Uterine prolapse; Painful and swollen testis.
Thin Caulis Piperis Boehmeriaefolii [source] medical material Ji Yuan: for Piperaceae plants the Herb of the short Betel of thing.[nature and flavor] are pungent; Temperature [function cures mainly] expelling wind and cold; Eliminating stasis to stop pain; Subduing swelling and detoxicating.Main air pain of dampness syndrome; Numb limbs and tense tendons; Affection of exogenous wind-cold; Breath with cough; Coldness and pain in the epigastrium; Traumatic injury; Menoxenia; Dysmenorrhea; Puerperal abdonimal pain; Toothache; Furuncle swells and ache; Scald; Snake bite and insect sting.
Radix Rubi pirifolii [source] medical material Ji Yuan: be the root of rosaceous plant Folium pyri Fructus Rubi corchorifolii Immaturus.[nature and flavor] acid; Puckery; Cool [return through] lung; Liver Channel [function cures mainly] clearing away lung-heat to relieve cough; Promoting QI circulation for relieving depression.Main cough due to lung-heat, stagnation of QI hypochondriac pain, abdominal distention.
The filamentous that Alectoria virens Tayl. [source] is sent out for Usneaceae plant greenery.Filamentous can be adopted the whole year, removes impurity, dries.[nature and flavor] sweetness and bitterness, flat.[function cures mainly] except rheumatism, hemostasis and pain-relieving, regulating menstruation and activating blood, tranquillizing and allaying excitement, strengthening the spleen and stomach.Control impairment caused by overstrain lumbago and skelalgia, traumatic hemorrhage, menoxenia, uterine prolapse, leucorrhea, psychosis, epilepsy, hemiplegia, sexual impotence, have a dizzy spell.
Brightness Herba Alii fistulosi [source] medical material Ji Yuan: be herb and the seed of liliaceous plant Allium strictum schrader.[nature and flavor] acrid in the mouth; [function cures mainly] warm in nature relieving the exterior syndrome by diaphoresis; Warming middle-JIAO to dispel cold.Main cold; Cold and heat are lossless; Invasion by pathogenic cold is suffered from abdominal pain; Have loose bowels.
In the process of tcm syndrome differentiation and treatment, we can make a definite diagnosis in conjunction with B ultrasonic, hysteroscopy usually further.The clinical manifestation of cold blood stasis type endometrial hyperplasia is premenstrual or cold-type pain in the lower abdomen during menstruation, pain alleviated while getting warmth, and hypomenorrhea color is black dull block, alleviation of pain under block, and cold physique fear is cold, pale complexion, pain very then vomiting and nausea, or infertile, and tongue is dark, and tongue is white, stringy and tense pulse.Therapeutic Principle is dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling.The present invention adopts formula and the proportioning of science, and 3 the golden grass adopted in formula have effect of promoting the circulation of QI to relieve pain, dispelling cold by warming the meridian, removing toxic substances; Herba seu Radix Metaplexis hemsleyanae has effect of dispelling cold by warming the meridian, relieving cough and resolving phlegm, reducing swelling and alleviating pain; Herba Colei Pumili has effect of dispelling cold by warming the meridian, expelling phlegm for arresting cough, dissipating blood stasis for subsidence of swelling, promoting the circulation of QI to relieve pain; Herba Sidae Szechuensis has stimulating milk secretion, invigorates blood circulation, dampness removing, removing toxic substances effect; Long tube Vespertilio grass has effect of blood circulation promoting and blood stasis dispelling, removing toxic substances and promoting subsidence of swelling, pain relieving; Radix seu Folium Rubi alceaefolii has effect of clearing away heat-damp and promoting diuresis, hemostasis, dissipating blood stasis; Break the effect of strangling and there is clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, lactogenic by a fall; Cortex Trematis Cannabinae Radicis has effect of diuretic, removing toxic substances, blood circulation promoting and blood stasis dispelling; Folium Paraquilegiae microphyllae has effect of blood circulation promoting and blood stasis dispelling, sore hemostasis; Effect that Herba pratiae begonifoliae has expelling wind and removing dampness, invigorates blood circulation, detoxifies; Cognate bell perfume (or spice) has effect of dispelling wind, cold expelling, dredging collateral; Fructus seu semen euscaphis japonicae has effect of expelling wind and cold, promoting the circulation of QI to relieve pain, dispersing swelling and dissipating binds; Thin Caulis Piperis Boehmeriaefolii has effect of expelling wind and cold, eliminating stasis to stop pain, subduing swelling and detoxicating; Radix Rubi pirifolii has effect of clearing away lung-heat to relieve cough, promoting QI circulation for relieving depression; Alectoria virens Tayl. has the effect except rheumatism, hemostasis and pain-relieving, regulating menstruation and activating blood, tranquillizing and allaying excitement, strengthening the spleen and stomach; Brightness Herba Alii fistulosi has effect of relieving the exterior syndrome by diaphoresis, warming middle-JIAO to dispel cold.Cooperatively interact between each medicine in formula, synergism, made Chinese medicine has effect of dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, can effectively treat cold blood stasis type endometrial hyperplasia, for many years, by the follow-up investigation statistics to 90 these type of patients of example, show that this prescription effective percentage reaches 95.5%.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, sampling approach
Be diagnosed as the patient of cold blood stasis type endometrial hyperplasia from my unit over nearly 5 years, the routine patient of random selecting 90, in age 30-60 year, be divided into matched group and treatment group at random, often organize each 45 people.The data there was no significant differences such as two groups of ages, have comparability.
2, test method
2.1 matched group patients use Shao Fu Zu Yu Wan, and by specification is taken, 6 weeks courses for the treatment of.
The oral the present invention of 2.2 treatment group according to the obtained Chinese medicinal granule of specific embodiment 1, early, middle and late each once.6 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect:
Clinical cure: clinical symptoms, the sign of cold blood stasis type endometrial hyperplasia disappear or substantially disappear; Effective: clinical symptoms, the sign of cold blood stasis type endometrial hyperplasia are obviously improved; Effective: clinical symptoms, the sign of cold blood stasis type endometrial hyperplasia all take a favorable turn; Invalid: clinical symptoms, the sign of cold blood stasis type endometrial hyperplasia are all not improved or increase the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
As can be seen here, the medicine adopting prescription of the present invention obtained can safe and effective treatment cold blood stasis type endometrial hyperplasia.
Detailed description of the invention
Below in conjunction with the concrete example implemented, further detailed description is done to the present invention.
Embodiment 1
Take 3 gold grass 15 grams, Herba seu Radix Metaplexis hemsleyanae 1 gram, Herba Colei Pumili 1 gram, Herba Sidae Szechuensis 9 grams, long tube Vespertilio grass 20 grams, Radix seu Folium Rubi alceaefolii 15 grams, Folium Paraquilegiae microphyllae 6 grams, Herba pratiae begonifoliae 12 grams, break by a fall strangle 9 grams, Cortex Trematis Cannabinae Radicis 15 grams, fragrant 10 grams of cognate bell, Fructus seu semen euscaphis japonicae 12 grams, carefully Caulis Piperis Boehmeriaefolii 6 grams of, Radix Rubi pirifolii 10 grams, Alectoria virens Tayl. 5 grams, brightness Herba Alii fistulosi 6 grams.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.
Be used for the treatment of cold blood stasis type endometrial hyperplasia.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 2
Take 3 gold grass 20 grams, Herba seu Radix Metaplexis hemsleyanae 3 grams, Herba Colei Pumili 3 grams, Herba Sidae Szechuensis 12 grams, long tube Vespertilio grass 25 grams, Radix seu Folium Rubi alceaefolii 20 grams, Folium Paraquilegiae microphyllae 9 grams, Herba pratiae begonifoliae 15 grams, break by a fall strangle 12 grams, Cortex Trematis Cannabinae Radicis 20 grams, fragrant 20 grams of cognate bell, Fructus seu semen euscaphis japonicae 15 grams, carefully Caulis Piperis Boehmeriaefolii 10 grams of, Radix Rubi pirifolii 15 grams, Alectoria virens Tayl. 10 grams, brightness Herba Alii fistulosi 12 grams.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.
Be used for the treatment of cold blood stasis type endometrial hyperplasia.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 3
Take 3 gold grass 18 grams, Herba seu Radix Metaplexis hemsleyanae 2 grams, Herba Colei Pumili 2 grams, Herba Sidae Szechuensis 10 grams, long tube Vespertilio grass 22 grams, Radix seu Folium Rubi alceaefolii 18 grams, Folium Paraquilegiae microphyllae 8 grams, Herba pratiae begonifoliae 14 grams, break by a fall strangle 10 grams, Cortex Trematis Cannabinae Radicis 17 grams, fragrant 15 grams of cognate bell, Fructus seu semen euscaphis japonicae 13 grams, carefully Caulis Piperis Boehmeriaefolii 8 grams of, Radix Rubi pirifolii 12 grams, Alectoria virens Tayl. 8 grams, brightness Herba Alii fistulosi 10 grams.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.
Be used for the treatment of cold blood stasis type endometrial hyperplasia.Oral, every bu is taken for early, middle and late three times.
Claims (2)
1. treat a Chinese medicine composition for cold blood stasis type endometrial hyperplasia, it is characterized in that being made up of the medical material of following weight proportion:
3 gold careless 15-20 parts, Herba seu Radix Metaplexis hemsleyanae 1-3 part, Herba Colei Pumili 1-3 part, Herba Sidae Szechuensis 9-12 part, long tube Vespertilio grass 20-25 part, Radix seu Folium Rubi alceaefolii 15-20 part, Folium Paraquilegiae microphyllae 6-9 part, Herba pratiae begonifoliae 12-15 part, the fragrant 10-20 part of cognate bell, Fructus seu semen euscaphis japonicae 12-15 part, carefully Caulis Piperis Boehmeriaefolii 6-10 part, Radix Rubi pirifolii 10-15 part, Alectoria virens Tayl. 5-10 part, brightness Herba Alii fistulosi 6-12 part.
2., according to the Chinese medicine composition for the treatment of cold blood stasis type endometrial hyperplasia according to claim 1, it is characterized in that adding breaking by a fall and strangle 9-12 part, Cortex Trematis Cannabinae Radicis 15-20 part.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102343019A (en) * | 2011-10-14 | 2012-02-08 | 孙丰卿 | Chinese medicinal composition for treating amenorrhea and preparation method of preparation thereof |
| CN104127848A (en) * | 2014-08-07 | 2014-11-05 | 冯苏涛 | Traditional Chinese medicine composition for treating uterine diseases and application thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102343019A (en) * | 2011-10-14 | 2012-02-08 | 孙丰卿 | Chinese medicinal composition for treating amenorrhea and preparation method of preparation thereof |
| CN104127848A (en) * | 2014-08-07 | 2014-11-05 | 冯苏涛 | Traditional Chinese medicine composition for treating uterine diseases and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 董秋梅等: "《朱宗元教授临症精要》", 31 January 2015, 中医古籍出版社 * |
| 马秀丽等: "子宫内膜病变的寒热辩证分析", 《师姐中西医结合杂志》 * |
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Application publication date: 20150603 |