CN104645205A - Traditional Chinese medicine effective part composition for treating hyperlipidemia and preparation method of composition - Google Patents
Traditional Chinese medicine effective part composition for treating hyperlipidemia and preparation method of composition Download PDFInfo
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- CN104645205A CN104645205A CN201510105745.9A CN201510105745A CN104645205A CN 104645205 A CN104645205 A CN 104645205A CN 201510105745 A CN201510105745 A CN 201510105745A CN 104645205 A CN104645205 A CN 104645205A
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Abstract
The invention discloses a traditional Chinese medicine effective part composition for treating hyperlipidemia and a preparation method of the composition. The traditional Chinese medicine effective part composition disclosed by the invention is prepared from American ginseng, radix ophiopogonis, schisandra chinensis, dendrobium, hawthorn fruit, amomum cardamomum, cowherb seed, pulp of cornus and panax notoginseng powder. The traditional Chinese medicine effective part composition can be applied to treatment of hyperlipidemia and other secondary symptoms such as fatty liver, has the advantages of significant curative effect and no toxic or side effect, and is suitable for application and popularization.
Description
Technical field
The present invention relates to Chinese medicine manufacture field, be specifically related to a kind of Chinese medicinal effective-part composition for the treatment of hyperlipemia and preparation method thereof.
Background technology
Hyperlipemia refers to the disease of a series of serious harm healths caused because blood lipid level is too high, as atherosclerosis, coronary heart disease, pancreatitis, diabetes, hypertension etc.
Treatment majority at present for hyperlipemia is all that Diet Therapy and Drug therapy combine.Wherein, mostly the medicine used in Drug therapy is the Western medicine to reduce cholesterol.But the side effect of Western medicine ubiquity is large, occurring heart-burn, vomiting after the lighter's patient medication, feel sick etc., there is shock in severe one.There is again the undesirable problem of therapeutic effect in the Chinese patent medicine of minority treatment hyperlipemia.
Summary of the invention
The object of the invention is the problems referred to above existed in the numerous medicines according to existing treatment hyperlipemia, provides the Chinese medicinal effective-part composition of the treatment hyperlipemia that a kind of therapeutic effect is good, toxic and side effects is low.
Another object of the present invention is to provide the preparation method of the Chinese medicinal effective-part composition of above-mentioned treatment hyperlipemia.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
Treat a Chinese medicinal effective-part composition for hyperlipemia, every part heavy 140g, is made up of following component:
Radix Panacis Quinquefolii 22 ~ 30g, Radix Ophiopogonis 20 ~ 26g, Chinese Magnoliavine 10 ~ 15g, Herba Dendrobii 15 ~ 20g, Fructus Crataegi 15 ~ 18g, Fructus Amomi Rotundus 6 ~ 12g, Semen Vaccariae 10 ~ 15g, Fructus Corni 15 ~ 18g and Radix Notoginseng powder 10 ~ 12g.
As a kind of preferred version, the heavy 140g of Chinese medicinal effective-part composition every part of above-mentioned treatment hyperlipemia, is made up of following component:
Radix Panacis Quinquefolii 24g, Radix Ophiopogonis 24g, Chinese Magnoliavine 12g, Herba Dendrobii 18g, Fructus Crataegi 17g, Fructus Amomi Rotundus 8g, Semen Vaccariae 11g, Fructus Corni 15g and Radix Notoginseng powder 11g.
Radix Notoginseng powder used herein Radix Notoginseng is directly worn into the fine powder of less than 20 microns, also can substitute with commercially available any brand Radix Notoginseng powder.
The preparation method of the Chinese medicinal effective-part composition for the treatment of hyperlipemia of the present invention is by each crude drug according to proportioning combination drying, and gained powder is medicine.
Compared with prior art, the present invention has following beneficial effect:
(1) Chinese medicinal effective-part composition for the treatment of hyperlipemia of the present invention has the fat that purifies the blood, QI invigorating, the effect such as to protect the liver;
(2) Chinese medicinal effective-part composition for the treatment of hyperlipemia of the present invention can fast treating hyperlipemia and other diseases of causing because of hyperlipemia, and therapeutic effect is good and have no side effect;
(3) raw material of the Chinese medicinal effective-part composition for the treatment of hyperlipemia of the present invention is easy to get, and preparation method is simple.
Detailed description of the invention
Explain the present invention further below in conjunction with specific embodiment, but embodiment does not limit in any form to the present invention.
Embodiment 1
The raw materials used medicine of Chinese medicinal effective-part composition of preparation a treatment hyperlipemia: Radix Panacis Quinquefolii 22g, Radix Ophiopogonis 20g, Chinese Magnoliavine 10g, Herba Dendrobii 17g, Fructus Crataegi 17g, Fructus Amomi Rotundus 9g, Semen Vaccariae 15g, Fructus Corni 18g and Radix Notoginseng powder (life) 12g.
Preparation method: by abundant for above-mentioned raw materials medicine combination drying, obtain mixed-powder, for subsequent use.
Embodiment 2
The raw materials used medicine of Chinese medicinal effective-part composition of preparation a treatment hyperlipemia: Radix Panacis Quinquefolii 30g, Radix Ophiopogonis 24g, Chinese Magnoliavine 15g, Herba Dendrobii 15g, Fructus Crataegi 15g, Fructus Amomi Rotundus 6g, Semen Vaccariae 10g, Fructus Corni 15g and Radix Notoginseng powder (life) 10g.
Preparation method: by abundant for above-mentioned raw materials medicine combination drying, obtain mixed-powder, for subsequent use.
Embodiment 3
The raw materials used medicine of Chinese medicinal effective-part composition of preparation a treatment hyperlipemia: Radix Panacis Quinquefolii 24g, Radix Ophiopogonis 24g, Chinese Magnoliavine 12g, Herba Dendrobii 18g, Fructus Crataegi 17g, Fructus Amomi Rotundus 8g, Semen Vaccariae 11g, Fructus Corni 15g and Radix Notoginseng powder (life) 11g.
Preparation method: by abundant for above-mentioned raw materials medicine combination drying, obtain mixed-powder, for subsequent use.
Experimental example 1
There is hyperlipemia in clinical definite, and through doctor, the measurement result of its T-CHOL (TC), triglyceride (TG) and HDL-cholesterol all determines that patient 400 example belonging to same level is treatment target, be divided into four groups, often organize 100 people.Experimental group is the powder of embodiment 1 gained, and instructions of taking is every day 2 times, and each 2g 20 days is a course for the treatment of.Matched group 1 is blank group, and matched group 2 is XUEZHIKANG JIAONANG (production of Wei Xin bio tech ltd of Beijing University) medicine groups, and matched group 3 is patent No. medicine groups for the treatment hyperlipemia disclosed in 201010178929.5.Matched group 2 and 3 dosage is all abided by medicine and is illustrated or follow the doctor's advice.
Diagnostic criteria: T-CHOL >=6.5mmol/L, triglyceride >=1.86mmol/L, high density lipoprotein sterin (HDL-C)≤2mmol/L, and get rid of Secondary Hyperlipidemia and drug induccd hyperlipemia.
Observation index: take a blood sample respectively for before and after medication 3 weeks and carry out lipid determination, blood sampling is forbidden drinking and high fat diet the previous day, adopts venous blood on an empty stomach after 12h.
Curative effect determinate standard: with reference to " new Chinese medicine guideline of clinical investigations ", effective refer to TC decline 20% or TG decline 40%; Effectively refer to TC decline 10 ~ 19% or TG decline 20 ~ 39%, HDL-C rising 0.104 ~ 0.26mmol/L; Invalid referring to does not reach above-mentioned standard or index rising.
Experimental result is as shown in table 1.In table 1, medication 20 days front and back blood lipid levels compare (mmol/L).
Table 1
| Group | TC | TG | HDL-C |
| Matched group 1 | 7.02 | 4.11 | 1.17 |
| Experimental group | 4.3 | 1.78 | 2.09 |
| Matched group 2 | 5.69 | 3.74 | 1.36 |
| Matched group 3 | 5.03 | 2.65 | 1.34 |
The overall efficiency of active component composition of the present invention is 98%, far above matched group 2 and 3.
Table 2
| Group | Effective | Effectively | Invalid |
| Matched group 1 | -- | -- | -- |
| Experimental group | 93 | 5 | 2 |
| Matched group 2 | 69 | 20 | 11 |
| Matched group 3 | 72 | 18 | 10 |
Claims (3)
1. treat a Chinese medicinal effective-part composition for hyperlipemia, it is characterized in that, every part of heavy 140g of described Chinese medicinal effective-part composition, is made up of following component:
Radix Panacis Quinquefolii 22 ~ 30g, Radix Ophiopogonis 20 ~ 26g, Chinese Magnoliavine 10 ~ 15g, Herba Dendrobii 15 ~ 20g, Fructus Crataegi 15 ~ 18g, Fructus Amomi Rotundus 6 ~ 12g, Semen Vaccariae 10 ~ 15g, Fructus Corni 15 ~ 18g and Radix Notoginseng powder 10 ~ 12g.
2. treat the Chinese medicinal effective-part composition of hyperlipemia according to claim 1, it is characterized in that, every part of heavy 140g of described Chinese medicinal effective-part composition, is made up of following component:
Radix Panacis Quinquefolii 24g, Radix Ophiopogonis 24g, Chinese Magnoliavine 12g, Herba Dendrobii 18g, Fructus Crataegi 17g, Fructus Amomi Rotundus 8g, Semen Vaccariae 11g, Fructus Corni 15g and Radix Notoginseng powder 11g.
3. treat the preparation method of the Chinese medicinal effective-part composition of hyperlipemia described in claim 1 or 2, to it is characterized in that each crude drug, according to proportioning combination drying, obtaining final product.
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| CN201510105745.9A CN104645205A (en) | 2015-03-11 | 2015-03-11 | Traditional Chinese medicine effective part composition for treating hyperlipidemia and preparation method of composition |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107158304A (en) * | 2017-05-28 | 2017-09-15 | 成都风靡生物科技有限公司 | It is a kind of to be used to treat Chinese medicine composition of hyperlipidemia and preparation method thereof |
Citations (4)
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|---|---|---|---|---|
| CN101229312A (en) * | 2007-01-23 | 2008-07-30 | 凌泰祥 | Medicine compounds capable of regulating hypertension, hyperlipemia and angina |
| CN101461896A (en) * | 2009-01-12 | 2009-06-24 | 东方药林药业有限公司 | Chinese medicinal composition assistant for reducing blood fat and preparation method thereof |
| CN101530209A (en) * | 2009-04-17 | 2009-09-16 | 同溢堂药业有限公司 | A health-care food capable of adjusting blood fat and protecting liver and preparation method thereof |
| CN101757499A (en) * | 2010-01-21 | 2010-06-30 | 浙江中医药大学 | Traditional Chinese medicine composite for treating impaired glucose tolerance |
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2015
- 2015-03-11 CN CN201510105745.9A patent/CN104645205A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229312A (en) * | 2007-01-23 | 2008-07-30 | 凌泰祥 | Medicine compounds capable of regulating hypertension, hyperlipemia and angina |
| CN101461896A (en) * | 2009-01-12 | 2009-06-24 | 东方药林药业有限公司 | Chinese medicinal composition assistant for reducing blood fat and preparation method thereof |
| CN101530209A (en) * | 2009-04-17 | 2009-09-16 | 同溢堂药业有限公司 | A health-care food capable of adjusting blood fat and protecting liver and preparation method thereof |
| CN101757499A (en) * | 2010-01-21 | 2010-06-30 | 浙江中医药大学 | Traditional Chinese medicine composite for treating impaired glucose tolerance |
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| 张保伟等: "糖尿血管舒治疗糖尿病血管病变30 例", 《光明中医》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107158304A (en) * | 2017-05-28 | 2017-09-15 | 成都风靡生物科技有限公司 | It is a kind of to be used to treat Chinese medicine composition of hyperlipidemia and preparation method thereof |
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